Form 8-K
8-K — RAPID MICRO BIOSYSTEMS, INC.
Accession: 0001104659-26-063936
Filed: 2026-05-19
Period: 2026-05-18
CIK: 0001380106
SIC: 3826 (LABORATORY ANALYTICAL INSTRUMENTS)
Item: Entry into a Material Definitive Agreement
Item: Financial Statements and Exhibits
Documents
8-K — tm2614922d1_8k.htm (Primary)
EX-1.1 — EXHIBIT 1.1 (tm2614922d1_ex1-1.htm)
EX-4.1 — EXHIBIT 4.1 (tm2614922d1_ex4-1.htm)
EX-4.2 — EXHIBIT 4.2 (tm2614922d1_ex4-2.htm)
EX-4.3 — EXHIBIT 4.3 (tm2614922d1_ex4-3.htm)
EX-5.1 — EXHIBIT 5.1 (tm2614922d1_ex5-1.htm)
EX-5.2 — EXHIBIT 5.2 (tm2614922d1_ex5-2.htm)
EX-10.1 — EXHIBIT 10.1 (tm2614922d1_ex10-1.htm)
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934
Date of report (Date of earliest event reported):
May 18, 2026
RAPID
MICRO BIOSYSTEMS, INC.
(Exact name of registrant as specified in its
charter)
Delaware
001-40592
20-8121647
(State or other jurisdiction
of incorporation or organization)
(Commission
File Number)
(I.R.S. Employer
Identification No.)
25 Hartwell Avenue, Lexington, MA
02421
(Address of principal executive offices)
(Zip Code)
978-349-3200
(Registrant’s telephone number, including
area code)
Not Applicable
(Former Name or Former Address, if Changed Since
Last Report)
Check the appropriate box below if the Form 8-K
filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
¨
Written
communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
¨
Soliciting
material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
¨
Pre-commencement
communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
¨
Pre-commencement
communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of
the Act:
Title of each class
Trading
Symbols
Name of each exchange on which
registered
Class A Common Stock, $0.01 par value per share
RPID
The Nasdaq Capital Market
Indicate by check mark whether the registrant
is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2
of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging
growth company x
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨
Item 1.01
Entry into a Material Definitive Agreement.
Underwriting Agreement
On May 18, 2026, Rapid Micro Biosystems, Inc. (the “Company”)
entered into an underwriting agreement (the “Underwriting Agreement”) with TD Securities (USA) LLC and Lake Street Capital
Markets LLC, as representatives of the several underwriters named therein (the “Underwriters”) relating to an underwritten
offering (the “Offering”) of (i) 3,581,000 shares (the “Shares”) of the Company’s Class A common
stock, $0.01 par value per share (the “Common Stock”) and accompanying Series A warrants (“Series A Common
Stock Warrants”) to purchase an aggregate of 3,581,000 shares of Class A common stock (or pre-funded warrants in lieu thereof)
and Series B warrants (“Series B Common Stock Warrants”) to purchase an aggregate of 3,581,000 shares of Class A
common stock (or pre-funded warrants in lieu thereof), and, (ii) in lieu of Common Stock to certain investors, pre-funded warrants
to purchase an aggregate of up to 1,463,000 shares of Common Stock (the “Pre-Funded Warrants” and together with the Series A
Common Stock Warrants, and Series B Common Stock Warrants, the “Warrants” and the shares of Common Stock issuable upon
exercise of the warrants, the “Warrant Shares”) and accompanying Series A Common Stock Warrants to purchase an aggregate
of 1,463,000 shares of Class A common stock (or pre-funded warrants in lieu thereof) at an exercise price of $1.955 per share and
Series B Common Stock Warrants to purchase an aggregate of 1,463,000 shares of Class A common stock (or pre-funded warrants
in lieu thereof) at an exercise price of $2.340 per share. Each Share was offered and sold together with an accompanying Series A
Common Stock Warrant and a Series B Common Stock Warrant at a combined offering price of $1.955, and each Pre-Funded Warrant was
offered and sold together with an accompanying Series A Common Stock Warrant and a Series B Common Stock Warrant at a combined
offering price of $1.945, which is equal to the combined offering price per share of Common Stock and accompanying Series A Common
Stock Warrant and Series B Common Stock Warrant less the $0.01 exercise price of each Pre-Funded Warrant. The Offering is expected
to close on May 20, 2026, subject to customary closing conditions.
Each Pre-Funded Warrant has an initial exercise price per share of
$0.01, subject to certain adjustments. The Pre-Funded Warrants are exercisable immediately and may be exercised at any time until all
of the Pre-Funded Warrants are exercised in full. Each Series A Common Stock Warrant has an initial exercise price per share of $1.955,
subject to certain adjustments and each Series B Common Stock Warrant has an initial exercise price per share of $2.340, subject
to certain adjustments. The Series A Common Stock Warrants are exercisable 6 months from the date of issuance and will expire one
year from the date of issuance. The Series B Common Stock Warrants are exercisable 6 months from the date of issuance and will expire
five years from the date of issuance.
Under the Warrants, the Company
may not effect the exercise of any Warrant, and a holder will not be entitled to exercise any portion of any Warrant (i) if immediately
prior to the exercise, holder (together with its affiliates), beneficially own an aggregate number of shares of Common Stock greater than
4.5% or 4.99% or 9.99%, as applicable (the “Maximum Percentage”) of the total number of issued and outstanding shares of Common
Stock of the Company without taking into account any Warrant Shares, or (ii) to the extent that immediately following the exercise,
the holder (together with its affiliates) would beneficially own in excess of the Maximum Percentage of the number of shares of Common
Stock outstanding immediately after giving effect to the issuance of such shares of Common Stock, which such percentage may be changed
at the holder’s election to a higher or lower percentage not in excess of 19.99% upon 61 days’ notice to the Company.
The Series A Common Stock
Warrants include certain rights upon “fundamental transactions” as described therein, including the right of the holders thereof
to receive, upon exercise of the Series A Common Stock Warrants following such fundamental transaction, the same amount and kind
of securities, cash or property as the holder would have been entitled to receive upon the occurrence of such fundamental transaction
if it had been, immediately prior to such fundamental transaction, the holder of the number of Warrant Shares issuable upon exercise of
the Series A Common Stock Warrants.
The Series
A Common Stock Warrants also contain a forced exercise provision granting the Company the right, upon the satisfaction of specified conditions,
to require holders to exercise all or any portion of their Series A Common Stock Warrants.
The Series B Common Stock
Warrants include certain rights upon “fundamental transactions” as described therein, including the right of the holders thereof
to receive from the Company or a successor entity the same type or form of consideration (and in the same proportion) that is being offered
and paid to the holders of Common Stock in such fundamental transaction in the amount of the Black Scholes Value (as described in such
Series A Common Stock Warrants) of the unexercised portion of the applicable Series B Common Stock Warrants on the date of the
consummation of such fundamental transaction.
The Series B Common Stock
Warrants also include a participation rights whereby for a period of twelve months from the original issue date, holders of the Series
B Common Stock Warrants have the right to participate in future issuances of the Company’s Class A common stock or Common Stock
equivalents on pro rata basis, up to an aggregate of 25% of such offering, subject to certain conditions.
The Company estimates that
the net proceeds from the Offering will be approximately $8.9 million, after deducting underwriting discounts and commissions and estimated
offering expenses payable by the Company. The Company intends to use the net proceeds from the Offering to fund working capital and other
general corporate purposes.
The Shares and the Warrants were issued pursuant to a shelf registration
statement on Form S-3 (File No. 333-276081), as filed with the U.S. Securities and Exchange Commission (“SEC”) on
December 15, 2023 and declared effective on December 26, 2023 (the “Registration Statement”), and a related prospectus
included in the Registration Statement, as supplemented by a prospectus supplement dated May 18, 2026.
The Underwriting Agreement
contains customary representations, warranties, covenants, indemnification obligations of the Company and the Underwriters, including
for liabilities under the Securities Act of 1933, as amended, and other obligations of the parties. The representations, warranties and
covenants contained in the Underwriting Agreement were made only for purposes of such agreement and as of specific dates, were solely
for the benefit of the parties to such agreement, and may be subject to limitations agreed upon by the contracting parties. The foregoing
is only a brief description of the terms of the Underwriting Agreement, does not purport to be a complete statement of the rights and
obligations of the parties under the Underwriting Agreement and the transactions contemplated thereby, and is qualified in its entirety
by reference to the Underwriting Agreement, which is filed as Exhibit 1.1 to this Current Report on Form 8-K and is incorporated
herein by reference.
The foregoing is only a brief
description of the terms of the form of Warrants, does not purport to be a complete statement of the rights and obligations of the parties
thereto and the transactions contemplated thereby, and is qualified in its entirety by reference to the form of Pre-Funded Warrant, the
form of Series A Common Stock Warrant and form of Series B Common Stock Warrant that are filed as Exhibit 4.1, Exhibit 4.2
and Exhibit 4.3, respectively, to this Current Report on Form 8-K and are incorporated herein by reference.
A copy of the legal opinion
of Goodwin Procter LLP, relating to the validity of the shares issued in the Offering is filed as Exhibit 5.1 to this Current Report
on Form 8-K and is filed with reference to, and is hereby incorporated by reference into, the Registration Statement.
Securities Purchase Agreement
On May 18, 2026,
the Company also entered into a Securities Purchase Agreement (the “Purchase Agreement”) with certain of the
Company’s directors and officers (the “D&Os”). Pursuant to the Purchase Agreement, the Company agreed to issue
and sell to the D&Os in a registered direct offering 71,607 shares of Common Stock and accompanying Series A Common Stock
Warrants to purchase an aggregate of 71,607 shares of Common Stock (or Pre-Funded Warrants in lieu thereof) with an exercise price
of $1.955 per share and Series B Common Stock warrants to purchase an aggregate of 71,607 shares of Common Stock (or Pre-Funded
Warrants in lieu thereof) with an exercise price of $2.34 per share (the “Concurrent Offering”) for gross proceeds of
approximately $140,000. Each Share was offered and sold together with an accompanying Series A Common Stock Warrant and a
Series B Common Stock Warrant at a combined offering price of $1.955. The terms of the Series A Common Stock Warrants and
Series B Common Stock Warrants sold to investors in the Concurrent Offering are identical to those sold to investors in the
Offering. The Concurrent Offering was made without an underwriter or placement agent. The Company intends to use the net proceeds of
the Concurrent Offering to fund working capital and other general corporate purposes. The Concurrent Offering is anticipated to
close on or about May 20, 2026, and is contingent and conditioned upon consummation of, the Offering, as well as certain other
customary closing conditions in the Purchase Agreement.
The Purchase Agreement contains
customary representations, warranties, and agreements by the Company. The foregoing summary of the Purchase Agreement is qualified in
its entirety by the full text of the Purchase Agreement, which is filed herewith as Exhibit 10.1 and incorporated herein by reference.
The securities in the Concurrent Offering were offered and sold by
the Company pursuant to the Registration Statement, and a related prospectus included in the Registration Statement, as supplemented by
a prospectus supplement dated May 18, 2026.
A copy of the legal opinion
of Goodwin Procter LLP, relating to the validity of the shares issued in the Concurrent Offering, is filed as Exhibit 5.2 to this
Current Report on Form 8-K and is filed with reference to, and is hereby incorporated by reference into, the Registration Statement.
Item 9.01
Financial Statements and Exhibits.
(d) Exhibits.
Exhibit
No.
Description
1.1
Underwriting Agreement, dated as of May 18, 2026, by and among the Company, TD Securities (USA) LLC and Lake Street Capital Markets LLC, as representatives of the several underwriters named therein.
4.1
Form of Pre-Funded Warrant
4.2
Form of Series A Common Stock Warrant
4.3
Form of Series B Common Stock Warrant
5.1
Opinion of Goodwin Procter LLP
5.2
Opinion of Goodwin Procter LLP
10.1
Securities Purchase Agreement, dated as of May 18, 2026, by and between the Company and the purchasers named therein.
23.1
Consent of Goodwin Procter LLP (included in Exhibit 5.1)
23.2
Consent of Goodwin Procter LLP (included in Exhibit 5.2)
104
Cover Page Interactive Data File (formatted as inline XBRL)
SIGNATURES
Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
RAPID MICRO BIOSYSTEMS, INC.
Date: May 19, 2026
By:
/s/ Sean Wirtjes
Sean Wirtjes
Chief Financial Officer
EX-1.1 — EXHIBIT 1.1
EX-1.1
Filename: tm2614922d1_ex1-1.htm · Sequence: 2
Exhibit 1.1
3,581,000 Shares of Common Stock
Pre-Funded Warrants to Purchase 1,463,000 Shares
of Common Stock
Series A Warrants to Purchase 5,044,000
Shares of Common Stock (or Pre-Funded Warrants in lieu thereof)
Series B Warrants to Purchase 5,044,000
Shares of Common Stock (or Pre-Funded Warrants in lieu thereof)
Rapid Micro Biosystems, Inc.
UNDERWRITING AGREEMENT
May 18, 2026
TD Securities
(USA) LLC
Lake Street
Capital Markets, LLC
As Representatives of the several Underwriters
c/o TD Securities (USA) LLC
1 Vanderbilt Avenue
New York, New York 10017
c/o Lake Street Capital Markets, LLC
121 South 8th Street, Suite 1000
Minneapolis, Minnesota 55402
Dear Sirs:
1. Introductory.
Rapid Micro Biosystems, Inc., a Delaware corporation (the “Company”), proposes to sell, pursuant to the
terms of this Underwriting Agreement (this “Agreement”), to the several underwriters named in Schedule A
hereto (the “Underwriters,” or, each, an “Underwriter”), an aggregate of (a) 3,581,000
shares of Class A common stock, $0.01 par value (the “Common Stock”) of the Company (the “Firm
Stock”), (b) pre-funded warrants of the Company to purchase up to 1,463,000 shares of Common Stock (the “Pre-Funded
Warrants”), (c) accompanying Series A Common Stock warrants to purchase up to 5,044,000 shares of Common Stock
(or pre-funded warrants of the Company to purchase one share of Common Stock in lieu thereof (the “Series A Pre-Funded
Warrants”)) at an exercise price of $1.955 per share (the “Series A Common Warrants”), and
(c) accompanying Series B Common Stock warrants to purchase up to 5,044,000 shares of Common Stock (or pre-funded warrants of
the Company to purchase one share of Common Stock in lieu thereof (together with the “Series B Pre-Funded Warrants”))
at an exercise price of $2.340 per share (the “Series B Common Warrants,” together with Series A Common
Warrants, the “Common Warrants”). The shares of Common Stock issuable upon exercise of the Common Warrants are
herein referred to as the “Common Warrant Shares.” The shares of Common Stock issuable upon exercise of the
Pre-Funded Warrants (including the Series A Pre-Funded Warrants and Series B Pre-Funded Warrants) are herein referred to as
the “Pre-Funded Warrant Shares.” The Firm Stock, Common Warrants, Pre-Funded Warrants, Series A Pre-Funded
Warrants, Series B Pre-Funded Warrants, Common Warrant Shares and Pre-Funded Warrant Shares are hereinafter collectively referred
to as the “Securities.” Each share of the Firm Stock and Pre-Funded Warrant is being sold with one Series A
Common Warrant to purchase one share of Common Stock and one Series B Common Warrant to purchase one share of Common Stock or, in
each case, Pre-Funded Warrants in lieu thereof. TD Securities (USA) LLC (“TD Cowen”) and Lake Street Capital
Markets, LLC (“Lake Street”) are acting as representatives of the several Underwriters and in such capacity
are hereinafter referred to as the “Representatives.”
2
2. Representations
and Warranties of the Company. The Company represents and warrants to the several Underwriters, as of the date hereof and as
of each Closing Date (as defined below), and agrees with the several Underwriters, that:
(a) Registration
Statement. A registration statement of the Company on Form S-3 (File No. 333-276081) (including all amendments thereto,
the “Initial Registration Statement”) registering the offer and sale of the Securities has been filed with the
Securities and Exchange Commission (the “Commission”). The Initial Registration Statement and any post-effective
amendment thereto, each in the form heretofore delivered to you, and, excluding exhibits thereto, to you for each of the other Underwriters,
have been declared effective by the Commission in such form and meet the requirements of the Securities Act of 1933, as amended (the “Securities
Act”), and the rules and regulations of the Commission thereunder (the “Rules and Regulations”).
Other than (i) the Initial Registration Statement, (ii) a registration statement, if any, increasing the size of the offering
filed pursuant to Rule 462(b) under the Securities Act and the Rules and Regulations (a “Rule 462(b) Registration
Statement”), (iii) the Prospectus (as defined below) contemplated by this Agreement to be filed pursuant to Rule 424(b) of
the Rules and Regulations in accordance with Section 4(a) hereof and (iv) any Issuer Free Writing Prospectus (as defined
below), no other document with respect to the offer or sale of the Securities has heretofore been filed with the Commission. No stop order
suspending the effectiveness of the Initial Registration Statement, any post-effective amendment thereto or the Rule 462(b) Registration
Statement, if any, has been issued and no proceeding for that purpose or pursuant to Section 8A of the Securities Act has been initiated
or threatened by the Commission. The Initial Registration Statement including all exhibits thereto and including the information contained
in the Prospectus filed with the Commission pursuant to Rule 424(b) of the Rules and Regulations and deemed by virtue of
Rules 430A or 430B under the Securities Act to be part of the Initial Registration Statement at the time it became effective is hereinafter
collectively called the “Registration Statement.” If the Company has filed a Rule 462(b) Registration
Statement, then any reference herein to the term “Registration Statement” shall be deemed to include such Rule 462 Registration
Statement. The base prospectus included in the Initial Registration Statement at the time of effectiveness thereof, as supplemented by
the final prospectus supplement relating to the offer and sale of the Securities, in the form filed pursuant to and within the time limits
described in Rule 424(b) under the Rules and Regulations, is hereinafter called the “Prospectus.”
Any reference herein to the Registration Statement or the Prospectus shall be deemed to refer to and include the documents incorporated
by reference therein. Any reference to any amendment or supplement to the Prospectus shall be deemed to refer to and include any documents
filed after the date of the Prospectus under the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
and incorporated by reference in such Prospectus, as the case may be. Any reference to (i) the Registration Statement shall be deemed
to refer to and include the annual report of the last completed fiscal year of the Company on Form 10-K filed under Section 13(a) or
15(d) of the Exchange Act prior to the date hereof and (ii) the effective date of such Registration Statement shall be deemed
to refer to and include the date such Registration Statement became effective and, if later, the date such Form 10-K was so filed.
Any reference to any amendment to the Registration Statement shall be deemed to refer to and include any annual report of the Company
filed pursuant to Section 13(a) or 15(d) of the Exchange Act after the date of this Agreement that is incorporated by reference
in the Registration Statement.
3
(b) General
Disclosure Package. As of the Applicable Time (as defined below) and as of the Closing Date or the Option Closing Date (as defined
below), as the case may be, neither (i) the General Use Free Writing Prospectus(es) (as defined below) issued at or prior to the
Applicable Time, the Pricing Prospectus (as defined below), and the information included on Schedule C hereto, all considered together
(collectively, the “General Disclosure Package”), (ii) any individual Limited Use Free Writing Prospectus
(as defined below), (iii) the bona fide electronic roadshow (as defined in Rule 433(h)(5) of the Rules and Regulations);
nor (iv) any individual Written Testing-the-Waters Communication (as defined below), when considered together with the General Disclosure
Package, included or will include any untrue statement of a material fact or omitted or will omit to state a material fact necessary in
order to make the statements therein, in the light of the circumstances under which they were made, not misleading; provided, however,
that the Company makes no representations or warranties as to information contained in or omitted from the Pricing Prospectus or any Issuer
Free Writing Prospectus (as defined below), in reliance upon, and in conformity with, written information furnished to the Company through
the Representatives by or on behalf of any Underwriter specifically for inclusion therein, which information the parties hereto agree
is limited to the Underwriters’ Information (as defined in Section 18). As used in this paragraph (b) and elsewhere in
this Agreement:
“Applicable Time”
means 9:00 pm, New York time, on the date of this Agreement or such other time as agreed to by the Company and the Representatives.
“Pricing Prospectus”
means the base prospectus filed as part of the Registration Statement in the form in which it has most recently been filed with the Commission
on or prior to the date of this Agreement, as amended and supplemented immediately prior to the Applicable Time, including any document
incorporated by reference therein and any prospectus supplement deemed to be a part thereof.
“Issuer Free Writing
Prospectus” means any “issuer free writing prospectus,” as defined in Rule 433 of the Rules and Regulations
relating to the Securities in the form filed or required to be filed with the Commission or, if not required to be filed, in the form
retained in the Company’s records pursuant to Rule 433(g) of the Rules and Regulations.
“General Use Free
Writing Prospectus” means any Issuer Free Writing Prospectus that is identified on Schedule B to this Agreement.
“Limited Use Free
Writing Prospectus” means any Issuer Free Writing Prospectus that is not a General Use Free Writing Prospectus.
“Written Testing-the-Waters
Communication” means any Testing-the-Waters Communication (as defined below) that is a written communication within the
meaning of Rule 405 of the Rules and Regulations.
(c) No
Stop Orders; No Material Misstatements. No order preventing or suspending the use of any Issuer Free Writing Prospectus or the Prospectus
relating to the proposed offering of the Securities has been issued by the Commission, and no proceeding for that purpose or pursuant
to Section 8A of the Securities Act has been instituted or threatened by the Commission.
(d) Registration
Statement and Prospectus Contents. At the respective times, the Registration Statement and any amendments thereto became or become
effective as to the Underwriters and at each Closing Date, the Registration Statement and any amendments thereto conformed and will conform
in all material respects to the requirements of the Securities Act and the Rules and Regulations and did not and will not contain
any untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary to make the statements
therein not misleading; and the Prospectus and any amendments or supplements thereto, at the time the Prospectus or any amendment or supplement
thereto was issued and at each Closing Date, conformed and will conform in all material respects to the requirements of the Securities
Act and the Rules and Regulations and did not and will not contain an untrue statement of a material fact or omit to state a material
fact necessary in order to make the statements therein, in the light of the circumstances under which they were made, not misleading;
provided, however, that the foregoing representations and warranties in this paragraph (d) shall not apply to information
contained in or omitted from the Registration Statement or the Prospectus, or any amendment or supplement thereto, in reliance upon, and
in conformity with, written information furnished to the Company through the Representatives by or on behalf of any Underwriter specifically
for inclusion therein, which information the parties hereto agree is limited to the Underwriters’ Information.
4
(e) Issuer
Free Writing Prospectus. Each Issuer Free Writing Prospectus, as of its issue date and at all subsequent times through the completion
of the public offer and sale of the Securities or until any earlier date that the Company notified or notifies the Representatives as
described in Section 4(f), did not, does not and will not include any information that conflicted, conflicts or will conflict with
the information contained in the Registration Statement, Pricing Prospectus or the Prospectus, including any document incorporated by
reference therein and any prospectus supplement deemed to be a part thereof that has not been superseded or modified, or included or would
include an untrue statement of a material fact or omitted or would omit to state a material fact required to be stated therein or necessary
in order to make the statements therein, in the light of the circumstances under which they were made, not misleading, provided,
however, that the foregoing representations and warranties in this paragraph (e) shall not apply to information contained
in or omitted from such Issuer Free Writing Prospectus, the Registration Statement or the Prospectus, or any amendment or supplement thereto,
in reliance upon, and in conformity with, written information furnished to the Company through the Representatives by or on behalf of
any Underwriter specifically for inclusion therein, which information the parties hereto agree is limited to the Underwriters’ Information.
(f) Documents
Incorporated by Reference. The documents incorporated, or deemed to be incorporated, by reference in the Prospectus, when they were
filed with the Commission, conformed in all material respects to the requirements of the Securities Act or the Exchange Act, as applicable,
and the rules and regulations of the Commission thereunder and none of such documents contained any untrue statement of a material
fact or omitted to state any material fact required to be stated therein, or necessary to make the statements therein, in the light of
the circumstances under which they were made, not misleading; and any further documents so filed and incorporated by reference in the
Prospectus, when such documents are filed with Commission will conform in all material respects to the requirements of the Securities
Act or the Exchange Act, as applicable, and the rules and regulations of the Commission thereunder and will not contain any untrue
statement of a material fact or omit to state any material fact required to be stated therein or necessary to make the statements therein,
in the light of the circumstances under which they were made, not misleading.
(g) Distribution
of Offering Materials. The Company has not distributed and will not distribute any offering material in connection with the offering
and sale of the Securities other than the Prospectus and other materials, if any, permitted under the Securities Act and consistent with
Section 4(c) below. The Company will file with the Commission all Issuer Free Writing Prospectuses (other than a “road
show” as described in Rule 433(d)(8) of the Rules and Regulations) in the time and manner required under Rules 163(b)(2) and
433(d) of the Rules and Regulations.
(h) Emerging
Growth Company. From the first date on which the Company engaged directly or through any person authorized to act on its behalf in
any Testing-the-Waters Communications in reliance on Section 5(d) of the Securities Act through the date hereof, the Company
has been and is an “emerging growth company,” as defined in Section 2(a) of the Securities Act (an “Emerging
Growth Company”).
5
(i) Not
an Ineligible Issuer. At the time of filing the Initial Registration Statement, any Rule 462(b) Registration Statement and
any post-effective amendments thereto, and at the date hereof, the Company was not, and the Company currently is not, an “ineligible
issuer,” as defined in Rule 405 of the Rules and Regulations.
(j) Testing
the Waters Communications. The Company (a) has not alone engaged in any Testing-the-Waters Communication other than Testing-the-Waters
Communications with the consent of the Representatives with entities that are qualified institutional buyers within the meaning of Rule 144A
under the Securities Act or institutions that are accredited investors within the meaning of Rule 501 under the Securities Act and
(b) has not authorized anyone other than the Representatives to engage in Testing-the-Waters Communications. The Company reconfirms
that the Representatives have been authorized to act on its behalf in undertaking Testing-the-Waters Communications. The Company has not
distributed any Written Testing-the-Waters Communications. “Testing-the-Waters Communication” means any oral
or written communication with potential investors undertaken in reliance on Section 5(d) of the Securities Act or Rule 163B
of the Rules and Regulations.
(k) Organization
and Good Standing. The Company and each of its subsidiaries have been duly organized and are validly existing and in good standing
under the laws of their respective jurisdictions of organization, are duly qualified to do business and are in good standing in each jurisdiction
in which their respective ownership or lease of property or the conduct of their respective businesses requires such qualification, and
have all power and authority necessary to own or hold their respective properties and to conduct the businesses in which they are engaged,
except where the failure to be so qualified or in good standing or have such power or authority would not, individually or in the aggregate,
have a material adverse effect on the business, properties, management, financial position, stockholders’ equity, results of operations
or prospects of the Company and its subsidiaries taken as a whole or on the performance by the Company of its obligations under this Agreement
(a “Material Adverse Effect”). The Company does not own or control, directly or indirectly, any corporation,
association or other entity other than the subsidiaries listed in Exhibit 21 to the Company’s Annual Report on Form 10-K
for the year ended December 31, 2025.
(l) Underwriting
Agreement. This Agreement has been duly authorized, executed and delivered by the Company.
(m) The
Securities. The Firm Stock to be issued and sold by the Company to the Underwriters hereunder has been duly and validly authorized
and, when issued and delivered against payment therefor as provided herein, will be duly and validly issued, fully paid and non-assessable
and will conform in all material respects to the descriptions thereof in the Registration Statement, the General Disclosure Package and
the Prospectus; and the issuance of the Firm Stock is not subject to any preemptive or similar rights. The Common Warrants and Pre-Funded
Warrants have been duly and validly authorized by the Company, and when executed and delivered by the Company, including in the case of
the Series A Pre-Funded Warrants and Series B Pre-Funded Warrants, upon the exercise of the Common Warrants, will be valid and
binding agreements of the Company, enforceable against the Company in accordance with their terms, except as the enforcement thereof may
be limited by bankruptcy, insolvency, reorganization, moratorium or other similar laws relating to or affecting the rights and remedies
of creditors or by general equitable principles, and will conform in all material respects to the descriptions thereof in the Registration
Statement, the General Disclosure Package and the Prospectus. The Common Warrant Shares and Pre-Funded Warrant Shares have been duly and
validly authorized and reserved for issuance upon exercise of the Common Warrants and Pre-Funded Warrants, respectively, in a number sufficient
to meet the current exercise requirements. The Common Warrant Shares and Pre-Funded Warrant Shares, when issued and delivered upon exercise
of the Common Warrants and Pre-Funded Warrants, respectively, and in accordance therewith, will be duly and validly issued, fully paid
and non-assessable and will conform in all material respects to the descriptions thereof in the Registration Statement, the General Disclosure
Package and the Prospectus; and the issuance of the Common Warrant Shares and Pre-Funded Warrant Shares is not subject to any preemptive
or similar rights.
6
(n) Capitalization.
The Company has an authorized capitalization as is set forth in the Registration Statement, the General Disclosure Package and the Prospectus
under the heading “Capitalization.” All the outstanding shares of capital stock of the Company have been duly and validly
authorized and issued and are fully paid and non-assessable and are not subject to any pre-emptive or similar rights that have not been
duly waived or satisfied; except as described in or expressly contemplated by the Registration Statement, the General Disclosure Package
and the Prospectus, there are no outstanding rights (including, without limitation, pre-emptive rights that have not been duly waived
or satisfied), warrants or options to acquire, or instruments convertible into or exchangeable for, any shares of capital stock or other
equity interest in the Company or any of its subsidiaries, or any contract, commitment, agreement, understanding or arrangement of any
kind relating to the issuance of any capital stock of the Company or any such subsidiary, any such convertible or exchangeable securities
or any such rights, warrants or options; all outstanding shares of capital stock of the Company conform, and the Securities, when they
have been delivered and paid for in accordance with this Agreement, will conform, in all material respects to the description thereof
contained in the Registration Statement, the General Disclosure Package and the Prospectus; and all the outstanding shares of capital
stock or other equity interests of each subsidiary owned, directly or indirectly, by the Company have been duly and validly authorized
and issued, are fully paid and non-assessable and are owned directly or indirectly by the Company, free and clear of any lien, charge,
encumbrance, security interest, restriction on voting or transfer or any other claim of any third party.
(o) No
Registration Rights. No person has the right to require the Company or any of its subsidiaries to register any securities for sale
under the Securities Act by reason of the filing of the Registration Statement with the Commission or the issuance and sale of the Securities,
except for such rights as have been duly waived.
(p) No
Restrictions on Subsidiaries. No subsidiary of the Company is currently prohibited, directly or indirectly, under any agreement or
other instrument to which it is a party or is subject, from paying any dividends to the Company, from making any other distribution on
such subsidiary’s capital stock or similar ownership interest, from repaying to the Company any loans or advances to such subsidiary
from the Company or from transferring any of such subsidiary’s properties or assets to the Company or any other subsidiary of the
Company.
(q) No
Material Adverse Change. Subsequent to the respective dates as of which information
is given in the Registration Statement, the General Disclosure Package and the Prospectus, (i) there has not been any change
in the capital stock (other than the issuance of shares of Common Stock upon exercise of stock options and warrants described as outstanding
in, and the grant of options and awards, including restricted stock, under existing equity incentive plans described in, the Registration
Statement, the General Disclosure Package and the Prospectus), short-term debt or long-term debt of the Company or any of its subsidiaries,
or any dividend or distribution of any kind declared, set aside for payment, paid or made by the Company on any class of capital stock,
or any material adverse change, or any development involving a prospective material adverse change, in or affecting the business, properties,
management, financial position, stockholders’ equity, results of operations or prospects of the Company and its subsidiaries taken
as a whole; (ii) neither the Company nor any of its subsidiaries has entered into any transaction or agreement (whether or not in
the ordinary course of business) that is material to the Company and its subsidiaries taken as a whole or incurred any liability or obligation,
direct or contingent, that is material to the Company and its subsidiaries taken as a whole; and (iii) neither the Company nor any
of its subsidiaries has sustained any loss or interference with its business that is material to the Company and its subsidiaries taken
as a whole and that is either from fire, explosion, flood or other calamity, whether or not covered by insurance, or from any labor disturbance
or dispute or any action, order or decree of any court or arbitrator or governmental or regulatory authority, except in each case as otherwise
disclosed in the Registration Statement, the General Disclosure Package and the Prospectus.
7
(r) Independent
Accountants. PricewaterhouseCoopers LLP, who has certified certain financial statements of the Company and its subsidiaries, is an
independent registered public accounting firm with respect to the Company and its subsidiaries within the applicable rules and regulations
adopted by the Commission and the Public Company Accounting Oversight Board (United States) and as required by the Securities Act.
(s) Financial
Statements. The financial statements (including the related notes thereto) of the Company and its consolidated subsidiaries
included in or incorporated by reference in the Registration Statement, the General Disclosure Package and the Prospectus comply in all
material respects with the applicable requirements of the Securities Act and present fairly in all material respects the financial position
of the Company and its consolidated subsidiaries as of the dates indicated and the results of their operations and the changes in their
cash flows for the periods specified; such financial statements have been prepared in conformity with generally accepted accounting principles
(“GAAP”) in the United States applied on a consistent basis throughout the periods covered thereby, except in
the case of unaudited financial statements, which are subject to normal year-end adjustments and do not contain certain footnotes permitted
by applicable rules of the Commission; and any supporting schedules included in or incorporated by reference in the Registration
Statement, the General Disclosure Package and the Prospectus present fairly in all material respects the information required to be stated
therein; and the other financial information included in or incorporated by reference in the Registration Statement, the General Disclosure
Package and the Prospectus has been derived from the accounting records of the Company and its consolidated subsidiaries and presents
fairly in all material respects, on the basis stated therein, the information shown thereby. There are no “non-GAAP financial measures”
(as such term is defined by the rules and regulations of the Commission) required to comply with Regulation G of the Exchange Act
and Item 10 of Regulation S-K of the Securities Act, to the extent applicable in the Registration Statement, the General Disclosure Package
and the Prospectus.
(t) XBRL.
The interactive data in eXtensible Business Reporting Language included or incorporated by reference in the Registration Statement fairly
presents the information called for in all material respects and has been prepared in accordance with the Commission’s rules and
guidelines applicable thereto.
(u) Stock
Options. With respect to the stock options (the “Stock Options”) granted pursuant to the stock-based
compensation plans of the Company and its subsidiaries (the “Company Stock Plans”), (i) each Stock Option
intended to qualify as an “incentive stock option” under Section 422 of the Code so qualifies, (ii) each grant of
a Stock Option was duly authorized no later than the date on which the grant of such Stock Option was by its terms to be effective by
all necessary corporate action, including, as applicable, approval by the board of directors of the Company (or a duly constituted and
authorized committee thereof) and any required stockholder approval by the necessary number of votes or written consents, and the award
agreement governing such grant (if any) was duly executed and delivered by each party thereto, (iii) each such grant was made in
accordance with the terms of the Company Stock Plans and all applicable laws and regulatory rules or requirements, and (iv) each
such grant was properly accounted for in accordance with GAAP in the financial statements (including the related notes) of the Company.
8
(v) No
Violation or Default. Neither the Company nor any of its subsidiaries is (i) in violation of its charter or by-laws
or similar organizational documents; (ii) in default, and no event has occurred that, with notice or lapse of time or both, would
constitute such a default, in the due performance or observance of any term, covenant or condition contained in any indenture, mortgage,
deed of trust, loan agreement or other agreement or instrument to which the Company or any of its subsidiaries is a party or by which
the Company or any of its subsidiaries is bound or to which any property or asset of the Company or any of its subsidiaries is subject;
or (iii) in violation of any law or statute or any judgment, order, rule or regulation of any court or arbitrator or governmental
or regulatory authority having jurisdiction over the Company and its subsidiaries, except, in the case of clauses (ii) and (iii) above,
for any such default or violation that would not, individually or in the aggregate, reasonably be expected to have a Material Adverse
Effect.
(w) No
Conflicts. The execution, delivery and performance of this Agreement, the Common Warrants and the Pre-Funded Warrants
by the Company, the issuance and sale of the Securities and the consummation of the transactions contemplated by this Agreement and the
Prospectus will not (i) conflict with or result in a breach or violation of any of the terms or provisions of, or constitute a default
under, result in the termination, modification or acceleration of, or result in the creation or imposition of any lien, charge or encumbrance
upon any property, right or asset of the Company or any of its subsidiaries pursuant to, any indenture, mortgage, deed of trust, loan
agreement or other agreement or instrument to which the Company or any of its subsidiaries is a party or by which the Company or any of
its subsidiaries is bound or to which any property, right or asset of the Company or any of its subsidiaries is subject, (ii) result
in any violation of the provisions of the charter or by-laws or similar organizational documents of the Company or any of its subsidiaries
or (iii) result in the violation of any law or statute or any judgment, order, rule or regulation of any court or arbitrator
or governmental or regulatory authority having jurisdiction over the Company, except, in the case of clauses (i) and (iii) above,
for any such conflict, breach, violation, default, lien, charge or encumbrance that would not, individually or in the aggregate, reasonably
be expected to have a Material Adverse Effect.
(x) No
Consents Required. No consent, approval, authorization, order, registration or qualification of or with any court or arbitrator
or governmental or regulatory authority is required for the execution, delivery and performance by the Company of this Agreement, the
Common Warrants or the Pre-Funded Warrants, the issuance and sale of the Securities and the consummation of the transactions contemplated
by this Agreement, except for the registration of the Securities under the Securities Act and such consents, approvals, authorizations,
orders and registrations or qualifications as may be required by the Financial Industry Regulatory Authority, Inc. (“FINRA”)
and under applicable state securities laws in connection with the purchase and distribution of the Securities by the Underwriters.
(y) Legal
Proceedings. Except as described in the Registration Statement, the General Disclosure Package and the Prospectus, there
are no legal, governmental or regulatory investigations, actions, demands, claims, suits, arbitrations, inquiries or proceedings (“Actions”)
pending to which the Company or any of its subsidiaries is or may be a party or to which any property of the Company or any of its subsidiaries
is or may be the subject that, individually or in the aggregate, if determined adversely to the Company or any of its subsidiaries, could
reasonably be expected to have a Material Adverse Effect; no such Actions are threatened or, to the knowledge of the Company, contemplated
by any governmental or regulatory authority or threatened by others; and (i) there are no current or pending Actions that are required
under the Securities Act to be described in the Registration Statement, the General Disclosure Package or the Prospectus that are not
so described in the Registration Statement, the General Disclosure Package and the Prospectus and (ii) there are no statutes, regulations
or contracts or other documents that are required under the Securities Act to be filed as exhibits to the Registration Statement or described
in the Registration Statement, the General Disclosure Package or the Prospectus that are not so filed as exhibits to the Registration
Statement or described in the Registration Statement, the General Disclosure Package and the Prospectus.
9
(z) Title
to Real and Personal Property. The Company and its subsidiaries have good and marketable title in fee simple (in the case of real
property) to, or have valid rights to lease or otherwise use, all items of real and personal property that are material to the respective
businesses of the Company and its subsidiaries, in each case free and clear of all liens, encumbrances, claims and defects and imperfections
of title except those that (i) do not materially interfere with the use made and proposed to be made of such property by the Company
and its subsidiaries or (ii) could not reasonably be expected, individually or in the aggregate, to have a Material Adverse Effect.
(aa) Licenses
and Permits. The Company and its subsidiaries possess all licenses, sub-licenses, certificates, certifications, permits
and other authorizations issued by, and have made all declarations and filings with, the appropriate federal, state, local or foreign
governmental or regulatory authorities or national standards bodies that are necessary for the ownership or lease of their respective
properties or the conduct of their respective businesses as described in each of the Registration Statement, the General Disclosure Package
and the Prospectus, except where the failure to possess or make the same would not, whether individually or in the aggregate, reasonably
be expected to have a Material Adverse Effect; and except as described in each of the Registration Statement, the General Disclosure Package
and the Prospectus, neither the Company nor any of its subsidiaries has received notice of any revocation or modification of any such
license, sub-license, certificate, certification, permit or authorization or has any reason to believe that any such license, sub-license,
certificate, permit or authorization will not be renewed in the ordinary course except where such revocation or modifications would not,
whether individually or in the aggregate, reasonably be expected to have a Material Adverse Effect.
(bb) No
Labor Disputes. No labor disturbance by or dispute with employees of the Company or any of its subsidiaries exists or,
to the knowledge of the Company, is contemplated or threatened, and the Company is not aware of any existing or imminent labor disturbance
by, or dispute with, the employees of any of its or its subsidiaries’ principal suppliers, contractors or customers, in each case,
except as would not reasonably be expected to have a Material Adverse Effect.
(cc) Taxes. The
Company and its subsidiaries have paid all federal, state, local and foreign taxes and filed all tax returns required to be paid or filed
through the date hereof except where such failure to pay taxes or file such returns would not, individually or in the aggregate, have
a Material Adverse Effect; and except as otherwise disclosed in the Registration Statement, the General Disclosure Package or the Prospectus,
there is no tax deficiency that has been, or could reasonably be expected to be, asserted by a governmental authority against the Company
or any of its subsidiaries or any of their respective properties or assets except as would not, individually or in the aggregate, have
a Material Adverse Effect.
(dd) Investment
Company Act. The Company is not and, after giving effect to the offering and sale of the Securities and the application of the proceeds
thereof as described in the Registration Statement, the General Disclosure Package and the Prospectus, will not be required to register
as an “investment company” or an entity “controlled” by an “investment company” within the meaning
of the Investment Company Act of 1940, as amended, and the rules and regulations of the Commission thereunder (collectively, the
“Investment Company Act”).
(ee) Insurance. The
Company and its subsidiaries have insurance covering their respective properties, operations, personnel and businesses, including business
interruption insurance, which insurance is in amounts and insures against such losses and risks as are generally maintained by companies
engaged in the same or similar business and which the Company believes are adequate to protect the Company and its subsidiaries and their
respective businesses; and neither the Company nor any of its subsidiaries has (i) received notice from any insurer or agent of such
insurer that capital improvements or other expenditures are required or necessary to be made in order to continue such insurance or (ii) any
reason to believe that it will not be able to renew its existing insurance coverage as and when such coverage expires or to obtain similar
coverage at comparable cost from similar insurers as may be necessary to continue its business.
10
(ff) No
Stabilization. Neither the Company nor any of its subsidiaries or, to the knowledge of the Company, affiliates has taken,
directly or indirectly, any action designed to or that could reasonably be expected to cause or result in any stabilization or manipulation
of the price of any security of the Company.
(gg) Margin
Rules. Neither the issuance, sale and delivery of the Securities nor the application of the proceeds thereof by the Company as described
in each of the Registration Statement, the General Disclosure Package and the Prospectus will violate Regulation T, U or X of the Board
of Governors of the Federal Reserve System or any other regulation of such Board of Governors.
(hh) No
Undisclosed Relationships. No relationship, direct or indirect, exists between or among the Company or any of its subsidiaries, on
the one hand, and the directors, officers, stockholders, customers, suppliers or other affiliates of the Company or any of its subsidiaries,
on the other, that is required by the Securities Act to be described in each of the Registration Statement, the General Disclosure Package
and the Prospectus and that is not so described in such documents.
(ii) Forward-Looking
Statements. No forward-looking statement (within the meaning of Section 27A of the Securities Act and Section 21E
of the Exchange Act) included or incorporated by reference in any of the Registration Statement, the General Disclosure Package or the
Prospectus has been made or reaffirmed without a reasonable basis or has been disclosed other than in good faith.
(jj) Statistical
and Market Data. Nothing has come to the attention of the Company that has caused the Company to believe that the statistical
and market-related data included in each of the Registration Statement, the General Disclosure Package and the Prospectus is not based
on or derived from sources that are reliable and accurate in all material respects.
(kk) Sarbanes-Oxley
Act. There is and, since the effectiveness of the Registration Statement, there has been no failure on the part of the Company or,
to the knowledge of the Company, any of the Company’s directors or officers, in their capacities as such, to comply in all material
respects with any provision of the Sarbanes-Oxley Act of 2002, as amended and the rules and regulations promulgated in connection
therewith, including Section 402 related to loans.
(ll) No
Unlawful Payments. Neither the Company nor any of its subsidiaries or affiliates nor any director, officer or employee
of the Company or any of its subsidiaries nor, to the knowledge of the Company, any agent, affiliate, representative or other person associated
with or acting on behalf of the Company or any of its subsidiaries or affiliates has (i) used any corporate funds for any unlawful
contribution, gift, entertainment or other unlawful expense relating to political activity; (ii) made or taken an act in furtherance
of an offer, promise or authorization of any direct or indirect unlawful payment or benefit, including the giving or receipt of money,
property, gifts or anything else of value, to any foreign or domestic government official or employee, including of any government-owned
or controlled entity or of a public international organization, or any person acting in an official capacity for or on behalf of any of
the foregoing, or any political party or party official or candidate for political office; (iii) violated or is in violation of any
provision of the Foreign Corrupt Practices Act of 1977, as amended, or any applicable law or regulation implementing the OECD Convention
on Combating Bribery of Foreign Public Officials in International Business Transactions, or committed an offence under the Bribery Act
2010 of the United Kingdom or any other applicable anti-bribery or anti-corruption law; or (iv) made, offered, agreed, requested
or taken an act in furtherance of any unlawful bribe or other unlawful benefit, including, without limitation, any rebate, payoff, influence
payment, kickback or other unlawful or improper payment or benefit. The Company and its subsidiaries and affiliates have conducted their
businesses in compliance with applicable anti-corruption laws and have instituted, maintain and enforce, and will continue to maintain
and enforce policies and procedures reasonably designed to promote and ensure compliance with all applicable anti-bribery and anti-corruption
laws and with the representations and warranties contained herein. Neither the Company nor any of its subsidiaries will use, directly
or indirectly, the proceeds of the offering in furtherance of an offer, payment, promise to pay, or authorization of the payment or giving
of money, or anything else of value, to any person in violation of any applicable anti-corruption laws.
11
(mm) Compliance
with Anti-Money Laundering Laws. The operations of the Company and its subsidiaries are and have been conducted at all times in compliance
with applicable financial recordkeeping and reporting requirements, including those of the Currency and Foreign Transactions Reporting
Act of 1970, as amended, the Bank Secrecy Act, as amended by Title III of the Uniting and Strengthening America by Providing Appropriate
Tools Required to Intercept and Obstruct Terrorism Act of 2001 (USA PATRIOT Act), the applicable money laundering statutes of all jurisdictions
where the Company or any of its subsidiaries conducts business, the rules and regulations thereunder and any related or similar rules,
regulations or guidelines issued, administered or enforced by any governmental agency (collectively, the “Anti-Money Laundering
Laws”) and no action, suit or proceeding by or before any court or governmental agency, authority or body or any arbitrator
involving the Company or any of its subsidiaries with respect to the Anti-Money Laundering Laws is pending or, to the knowledge of the
Company, threatened.
(nn) No
Conflicts with Sanctions Laws. Neither the Company nor any of its subsidiaries, directors, officers or employees, nor,
to the knowledge of the Company, any agent, affiliate or other person associated with or acting on behalf of the Company or any of its
subsidiaries is, or is owned or controlled by one or more persons that are, currently the subject or the target of any sanctions administered
or enforced by the U.S. government, (including, without limitation, the Office of Foreign Assets Control of the U.S. Department of the
Treasury or the U.S. Department of State and including, without limitation, the designation as a “specially designated national”
or “blocked person”), the United Nations Security Council, the European Union, His Majesty’s Treasury or other relevant
sanctions authority (collectively, “Sanctions”). Neither the Company nor any of its subsidiaries, directors,
officers or employees, nor, to the knowledge of the Company, any agent, affiliate or other person associated with or acting on behalf
of the Company or any of its subsidiaries is, nor is owned or controlled by one or more persons that are, located, organized or resident
in a country or territory that is the subject or target of Sanctions, including, without limitation, the so-called Donetsk People’s
Republic, so-called Luhansk People’s Republic or any other Covered Region of Ukraine identified pursuant to Executive Order 14065,
the Crimea region of Ukraine, the non-government controlled areas of the Zaporizhzhia and Kherson Regions, Cuba, Iran, North Korea
and Syria (each, a “Sanctioned Country”). The Company will not directly or indirectly use the proceeds of the
offering of the Securities hereunder, or lend, contribute or otherwise make available such proceeds to any subsidiary, joint venture partner
or other person or entity (i) to fund or facilitate any activities of or business with any person or in any country or territory
that, at the time of such funding or facilitation, is the subject or target of Sanctions, (ii) to fund or facilitate any activities
of or business in any Sanctioned Country or (iii) in any other manner that will result in a violation by any person (including any
person participating in the transaction, whether as underwriter, advisor, investor or otherwise) of Sanctions. For the past five years,
the Company and its subsidiaries have not knowingly engaged in and are not now knowingly engaged in, and will not engage in, any dealings
or transactions with any person that at the time of the dealing or transaction is or was the subject or the target of Sanctions or with
any Sanctioned Country.
12
(oo) Accounting
Controls. The Company and its subsidiaries maintain systems of “internal control over financial reporting”
(as defined in Rule 13a-15(f) of the Exchange Act) that have been designed to comply with the requirements of the Exchange Act
applicable to the Company and have been designed by, or under the supervision of, their respective principal executive and principal financial
officers, or persons performing similar functions, to provide reasonable assurance regarding the reliability of financial reporting and
the preparation of financial statements for external purposes in accordance with GAAP. The Company and its subsidiaries maintain internal
accounting controls sufficient to provide reasonable assurance that (i) transactions are executed in accordance with management’s
general or specific authorizations; (ii) transactions are recorded as necessary to permit preparation of financial statements in
conformity with GAAP and to maintain asset accountability; (iii) access to assets is permitted only in accordance with management’s
general or specific authorization; and (iv) the recorded accountability for assets is compared with the existing assets at reasonable
intervals and appropriate action is taken with respect to any differences. Based on the Company’s most recent evaluation of its
internal controls over financial reporting, there are no material weaknesses in the Company’s internal controls. The Company’s
auditors and the Audit Committee of the Board of Directors of the Company have been advised of: (i) all significant deficiencies
and material weaknesses in the design or operation of internal controls over financial reporting which have adversely affected or are
reasonably likely to adversely affect the Company’s ability to record, process, summarize and report financial information; and
(ii) any fraud, whether or not material, that involves management or other employees who have a significant role in the Company’s
internal controls over financial reporting.
(pp) Disclosure
Controls. The Company and its subsidiaries maintain an effective system of “disclosure controls and procedures” (as defined
in Rule 13a-15(e) of the Exchange Act) that complies with the requirements of the Exchange Act and that has been designed to
ensure that information required to be disclosed by the Company in reports that it files or submits under the Exchange Act is recorded,
processed, summarized and reported within the time periods specified in the Commission’s rules and forms, including controls
and procedures designed to ensure that such information is accumulated and communicated to the Company’s management as appropriate
to allow timely decisions regarding required disclosure.
(qq) Certain
Environmental Matters. (i) The Company and its subsidiaries (x) are in compliance with all, and have not violated any, applicable
federal, state, local and foreign laws (including common law), rules, regulations, requirements, decisions, judgments, decrees, orders
and other legally enforceable requirements relating to pollution or the protection of human health or safety, the environment, natural
resources, hazardous or toxic substances or wastes, pollutants or contaminants (collectively, “Environmental Laws”);
(y) have received and are in compliance with all, and have not violated any, permits, licenses, certificates or other authorizations
or approvals required of them under any Environmental Laws to conduct their respective businesses; and (z) have not received notice
of any actual or potential liability or obligation under or relating to, or any actual or potential violation of, applicable Environmental
Laws, including for the investigation or remediation of any disposal or release of hazardous or toxic substances or wastes, pollutants
or contaminants, and have no knowledge of any event or condition that would reasonably be expected to result in any such notice; (ii) there
are no costs or liabilities associated with Environmental Laws of or relating to the Company or its subsidiaries, except in the case of
each of (i) and (ii) above, for any such matter as would not, individually or in the aggregate, reasonably be expected to have
a Material Adverse Effect; and (iii) except as described in the Registration Statement, the General Disclosure Package and the Prospectus,
(x) there is no proceeding that is pending, or that is known to be contemplated, against the Company or any of its subsidiaries under
any Environmental Laws in which a governmental entity is also a party, other than such proceeding regarding which it is reasonably believed
no monetary sanctions of $100,000 or more will be imposed, (y) the Company and its subsidiaries are not aware of any facts or issues
regarding compliance with Environmental Laws, or liabilities or other obligations under Environmental Laws or concerning hazardous or
toxic substances or wastes, pollutants or contaminants, that could reasonably be expected to have a Material Adverse Effect, and (z) none
of the Company or its subsidiaries anticipates material capital expenditures relating to any Environmental Laws.
13
(rr) Intellectual
Property. (i) The Company and its subsidiaries own, or have obtained valid and enforceable licenses for, all inventions
(including any “subject inventions” developed with government funding as described in clause (ii) below), patents, patent
applications, trademarks, service marks, trade names, trademark registrations, service mark registrations, domain names and other source
indicators, copyrights and copyrightable works, know-how, trade secrets, systems, procedures, proprietary or confidential information
and all other worldwide intellectual property, industrial property and proprietary rights (collectively, “Intellectual Property”)
used or proposed to be used in the current and proposed conduct of their respective businesses; (ii) as contemplated under the Bayh
Dole Act and its implementing regulations, the Company has timely submitted notices of election to retain title to any material subject
invention the Company developed using government funding; (iii) to the knowledge of the Company, the Company’s and its subsidiaries’
conduct of their respective businesses does not infringe, misappropriate or otherwise violate any intellectual property of any person
except those that would not reasonably be expected, individually or in the aggregate, to have a Material Adverse Effect; (iv) the
Company and its subsidiaries have not received any written notice of any claim relating to Intellectual Property and, to the knowledge
of the Company, no such claims have been threatened, except any such notice of claim or threatened claim that would not reasonably be
expected, individually or in the aggregate, to have a Material Adverse Effect; (v) to the knowledge of the Company, the Intellectual
Property of the Company and its subsidiaries is valid and enforceable and is not being infringed, misappropriated or otherwise violated
by any person in any respect that would reasonably be expected, individually or in the aggregate, to have a Material Adverse Effect; (vi) the
Company and its subsidiaries have complied in all material respects with the terms of each agreement pursuant to which Intellectual Property
has been licensed to the Company or any subsidiary, and all such agreements are in full force and effect; and (vii) the Company and
its subsidiaries have taken commercially reasonable steps to protect, maintain and safeguard the Intellectual Property owned by them,
including the execution of appropriate nondisclosure, confidentiality agreements and invention assignment agreements by their employees
and contractors, and, to the Company’s knowledge, no employee or contractor of the Company is in or has been in violation in a material
respect of any term of any employment contract, patent disclosure agreement, invention assignment agreement, non-competition agreement,
non-solicitation agreement, nondisclosure agreement, or any restrictive covenant to or with a former employer where the basis of such
violation relates to such employee’s employment with the Company.
(ss) Listing.
The Company is subject to and in compliance in all material respects with the reporting requirements of Section 13 or Section 15(d) of
the Exchange Act. The Common Stock is registered pursuant to Section 12(b) or Section 12(g) of the Exchange Act and
is listed on the Nasdaq, and the Company has taken no action designed to, or reasonably likely to have the effect of, terminating the
registration of the Common Stock under the Exchange Act or delisting the Common Stock from Nasdaq, nor has the Company received any notification
that the Commission or Nasdaq is contemplating terminating such registration or listing. All of the Firm Stock, the Common Warrant Shares
and Pre-Funded Warrant Shares that have been or may be sold under this Agreement have been approved for listing on the Nasdaq, subject
to official notice of issuance; the Company has taken all necessary actions to ensure that, upon and at all times after the Nasdaq shall
have approved the Firm Stock, the Common Warrant Shares and Pre-Funded Warrant Shares for listing, it will be in compliance with all applicable
corporate governance requirements set forth in the Nasdaq’s listing rules that are then in effect.
(tt) No
Broker’s Fees. Except pursuant to this Agreement, neither the Company nor any of its subsidiaries is a party to
any contract, agreement or understanding with any person (other than this Agreement) that would give rise to a valid claim against any
of them or any Underwriter for a brokerage commission, finder’s fee or like payment in connection with the offering and sale of
the Securities.
14
(uu) Cybersecurity;
Data Protection.
(i) Except,
in each case, as would not, individually or in the aggregate, reasonably be expected to have a Material Adverse Effect, the Company and
its subsidiaries comply and have at all times complied with applicable privacy, data security and data protection laws and regulations,
contractual obligations, applicable industry guidelines and codes of conduct including, to the extent applicable, the Payment Card Industry
Data Security Standard and Company policies applicable to the Company’s and its subsidiaries’ collection, handling, usage,
disclosure and storage of all personally identifiable data (“Personal Data”) (collectively, the “Privacy
Requirements”).
(ii) The
Company and its subsidiaries have policies and procedures in place in accordance in all material respects with applicable Privacy Requirements
and takes appropriate steps which are reasonably designed to comply in all material respects with such policies and procedures.
(iii) To
the extent required under applicable Privacy Requirements, the Company and its subsidiaries have required and do require third parties
to which they provide any Personal Data to maintain the privacy and security of such Personal Data, including by contractually requiring
such third parties to protect such Personal Data from unauthorized access by and/or disclosure to any unauthorized third parties, except
where a failure to do so would not, singly or in the aggregate, reasonably be expected to result in a Material Adverse Effect. Except
as would not, singly or in the aggregate, reasonably be expected to result in a Material Adverse Effect, neither the Company nor any of
its subsidiaries has experienced any security incident breaches, violations, or outages that has compromised the privacy and/or security
of any Personal Data and/or the information technology assets and equipment, computers, systems, networks, hardware, software, websites,
applications, and databases (collectively, “IT Systems”) through which any such Personal Data is collected or
processed or on which the Personal Data is stored, nor has there been any unauthorized uses of the same, except for those that have been
remedied without material costs or liability or the duty to notify any other person, nor any incidents under internal review or investigations
relating to the same.
(iv) Neither
the Company nor any of its subsidiaries has received written notice asserting a violation by the Company or any of its subsidiaries of
any of the Privacy Requirements. Neither the Company nor any of its subsidiaries is (i) currently conducting or paying for, in whole
or in part, any investigation, remediation, or other corrective action pursuant to any Privacy Requirements; or (ii) a party to any
order, decree, or agreement that imposes any obligation or liability by any governmental or regulatory authority under any Privacy Requirements.
(v) Except
as would not, singly or in the aggregate, reasonably be expected to result in a Material Adverse Effect, the Company’s and its subsidiaries’
IT Systems are adequate for, and operate and perform in all respects as required in connection with, the operation of the business of
the Company and its subsidiaries as currently conducted, free and clear of all material bugs, errors, defects, Trojan horses, time bombs,
malware and other corruptants. The Company has implemented and maintained commercially reasonable controls, policies, procedures, and
safeguards to maintain and protect its material confidential information and the integrity, continuous operation, redundancy and security
of all IT Systems and Personal Data used in connection with its businesses.
15
(vv) Compliance
with ERISA. (i) Each employee benefit plan, within the meaning of Section 3(3) of the Employee Retirement Income Security
Act of 1974, as amended (“ERISA”), for which the Company or any member of its “Controlled Group”
(defined as any entity, whether or not incorporated, that is under common control with the Company within the meaning of Section 4001(a)(14)
of ERISA or any entity that would be regarded as a single employer with the Company under Section 414(b),(c),(m) or (o) of
the Internal Revenue Code of 1986, as amended (the “Code”)) would have any liability (each, a “Plan”)
has been maintained in compliance with its terms and the requirements of any applicable statutes, orders, rules and regulations,
including but not limited to ERISA and the Code; (ii) no prohibited transaction, within the meaning of Section 406 of ERISA
or Section 4975 of the Code, has occurred with respect to any Plan, excluding transactions effected pursuant to a statutory or administrative
exemption; (iii) for each Plan that is subject to the funding rules of Section 412 of the Code or Section 302 of ERISA,
no Plan has failed (whether or not waived), or is reasonably expected to fail, to satisfy the minimum funding standards (within the meaning
of Section 302 of ERISA or Section 412 of the Code) applicable to such Plan; (iv) no Plan is, or is reasonably expected
to be, in “at risk status” (within the meaning of Section 303(i) of ERISA) and no Plan that is a “multiemployer
plan” within the meaning of Section 4001(a)(3) of ERISA is in “endangered status” or “critical status”
(within the meaning of Sections 304 and 305 of ERISA); (v) the fair market value of the assets of each Plan exceeds the present value
of all benefits accrued under such Plan (determined based on those assumptions used to fund such Plan); (vi) no “reportable
event” (within the meaning of Section 4043(c) of ERISA and the regulations promulgated thereunder) has occurred or is
reasonably expected to occur; (vii) each Plan that is intended to be qualified under Section 401(a) of the Code has received
a favorable determination letter, or is entitled to rely on an opinion letter, from the Internal Revenue Service, and to the knowledge
of the Company, nothing has occurred, whether by action or by failure to act, which would reasonably be expected to cause the loss of
such qualification; (viii) neither the Company nor any member of the Controlled Group has incurred, nor reasonably expects to incur,
any liability under Title IV of ERISA (other than contributions to the Plan or premiums to the Pension Benefit Guarantee Corporation,
in the ordinary course and without default) in respect of a Plan (including a “multiemployer plan” within the meaning of Section 4001(a)(3) of
ERISA); and (ix) none of the following events has occurred or is reasonably expected to occur: (A) a material increase in the
aggregate amount of contributions required to be made to all Plans by the Company or its Controlled Group affiliates in the current fiscal
year of the Company and its Controlled Group affiliates compared to the amount of such contributions made in the Company’s and its
Controlled Group affiliates’ most recently completed fiscal year; or (B) a material increase in the Company and its subsidiaries’
“accumulated post-retirement benefit obligations” (within the meaning of Accounting Standards Codification Topic 715-60) compared
to the amount of such obligations in the Company and its subsidiaries’ most recently completed fiscal year, except in each case
with respect to the events or conditions set forth in (i) through (ix) hereof, as would not, individually or in the aggregate,
reasonably be expected to have a Material Adverse Effect.
(ww) Regulatory
Compliance. Except as would not, singly or in the aggregate, reasonably be expected to have a Material Adverse Effect, the Company
has not received any U.S. Food and Drug Administration Form 483, written notice of adverse finding, warning letter, untitled letter
or other written correspondence or written notice from any court or arbitrator or governmental or regulatory authority alleging or asserting
non-compliance with the Federal Food, Drug, and Cosmetic Act or comparable foreign laws. Neither the Company, nor any of its subsidiaries
nor, to the Company’s knowledge, any of their respective employees, officers, directors, or agents has been excluded, suspended,
debarred or disqualified from participation in any U.S. federal health care program or human clinical research or, to the knowledge of
the Company, is subject to a governmental inquiry, investigation, proceeding, or other similar action that would reasonably be expected
to result in debarment, disqualification, suspension, or exclusion.
(xx) Export
and Import Laws. For the past five (5) years, each of the Company and its subsidiaries, and, to the Company’s knowledge,
each of their affiliates and any director, officer, agent or employee of, or other person, while acting on behalf of the Company, has
acted in compliance in all material respects with applicable Export and Import Laws (as defined below). There are no claims, complaints,
charges, investigations or proceedings pending or expected or, to the knowledge of the Company, threatened between the Company or any
of its subsidiaries and any governmental authority under any Export or Import Laws. The term “Export and Import Laws”
means the Arms Export Control Act, the International Traffic in Arms Regulations, the Export Administration Act of 1979, as amended, the
Export Administration Regulations, and all other laws and regulations of the United States government regulating the provision of services
to non-U.S. parties or the export and import of articles or information from and to the United States of America, and all similar laws
and regulations of any foreign government regulating the provision of services to parties not of the foreign country or the export and
import of articles and information from and to the foreign country to parties not of the foreign country.
16
(yy) No
Associated Persons; FINRA Matters. Neither the Company nor, to the knowledge of the Company, any of its affiliates (within the meaning
of FINRA Rule 5121(f)(1)) directly or indirectly controls, is controlled by, or is under common control with, or is an associated
person (within the meaning of Article I, Section 1(ee) of the By-laws of FINRA) of, any member firm of FINRA.
(zz) No
Acquisitions or Dispositions. Except as are described in the Registration Statement, the General Disclosure Package and the Prospectus,
there are no contracts, letters of intent, term sheets, agreement, arrangements or understandings with respect to the direct or indirect
acquisition or disposition by the Company of material interests in real or personal property.
(aaa) Outbound
Investments. Neither the Company nor any of its subsidiaries is a “covered foreign person”, as that term is defined in
31 C.F.R. § 850.209. Neither the Company nor any of its subsidiaries currently engages, or has plans to engage, directly or indirectly,
in a “covered activity”, as that term is defined in 31 C.F.R. § 850.208 (“Covered Activity”).
The Company does not have any joint ventures that engages in or plans to engage in any Covered Activity. The Company also does not, directly
or indirectly, hold a board seat on, have a voting or equity interest in, or have any contractual power to direct or cause the direction
of the management or policies of any person or persons that engages or plans to engage in any Covered Activity.
Any certificate signed by or on behalf of the
Company and delivered to the Representatives or to counsel for the Underwriters shall be deemed to be a representation and warranty by
the Company to each Underwriter as to the matters covered thereby.
3. Purchase,
Sale and Delivery of Offered Securities. On the basis of the representations, warranties and agreements herein contained, but
subject to the terms and conditions herein set forth, the Company agrees to sell to the Underwriters, and the Underwriters agree, severally
and not jointly, to purchase from the Company the respective numbers of shares of Firm Stock, Common Warrants and Pre-Funded Warrants
set forth opposite the names of the Underwriters in Schedule A hereto.
The purchase price to be paid
by the Underwriters to the Company for (i) the Firm Stock and accompanying Common Warrants will be $1.8377 per share and accompanying
Common Warrant (the “Common Stock Purchase Price”) and (ii) Pre-Funded Warrants and the accompanying Common
Warrants will be $1.8377 per Pre-Funded Warrant and accompanying Common Warrant (the “Pre-Funded Warrant Purchase Price”).
The Company will deliver the
Firm Stock to the Representatives for the respective accounts of the several Underwriters, through the facilities of The Depository Trust
Company, in each such case, issued in such names and in such denominations as the Representatives may direct by notice in writing to the
Company given at or prior to 12:00 Noon, New York time, on the first (1st) full business day preceding the Closing Date against payment
of the aggregate Common Stock Purchase Price therefor by wire transfer in federal (same day) funds to an account at a bank specified by
the Company payable to the order of the Company. Time shall be of the essence, and delivery at the time and place specified pursuant to
this Agreement is a further condition of the obligations of each Underwriter hereunder. The time and date of the delivery and closing
shall be at 10:00 A.M., New York time, on May 20, 2026, in accordance with Rule 15c6-1 of the Exchange Act. The time and date
of such payment and delivery are herein referred to as the “Closing Date.” The Closing Date and the location
of delivery of, and the form of payment for, the Firm Stock may be varied by agreement between the Company and the Representatives.
17
The Company will deliver,
or cause to be delivered, to the purchasers thereof the Common Warrants and Pre-Funded Warrants in accordance with the Underwriters’
instructions to be sold by them, in each case at the Closing Date, against payment of the aggregate Common Stock Purchase Price and Pre-Funded
Warrant Purchase Price, as applicable, by wire transfer in federal (same day) funds to an account at a bank specified by the Company payable
to the order of the Company. The Common Warrants and Pre-Funded Warrants will be made available for inspection by the Representatives
on the business day prior to the Closing Date.
Notwithstanding the foregoing,
the Company and the Representatives shall instruct the purchasers of the Pre-Funded Warrants and accompanying Common Warrants to make
payment for such Pre-Funded Warrants and accompanying Common Warrants on the Closing Date to the Company by wire transfer in immediately
available funds to the account specified by the Company for the aggregate Pre-Funded Warrant Purchase Price, in lieu of payment by the
Underwriters for such Pre-Funded Warrants and accompanying Common Warrants, and the Company shall deliver the Pre-Funded Warrants and
accompanying Common Warrants to such purchasers on such date in definitive paper form against such payment, in lieu of the Company’s
obligation to deliver such Pre-Funded Warrants and accompanying Common Warrants to the Representatives; provided that, the Underwriters
shall withhold $0.11730 per Pre-Funded Warrant and accompanying Common Warrant as an offset against the payment owed by the Underwriters
to the Company for the Firm Stock as payment for the underwriting discounts and commissions in respect of the Pre-Funded Warrants and
accompanying Common Warrants. In the event that any purchaser of the Pre-Funded Warrants and accompanying Common Warrants fails to make
payment to the Company for all or part of the Pre-Funded Warrants and accompanying Common Warrants on the Closing Date, the Representatives
shall either (i) make payment to the Company for such Pre-Funded Warrants and accompanying Common Warrants specified in this Section 3
or (ii) elect, by written notice to the Company, to receive shares of Common Stock at the Common Stock Purchase Price specified in
this Section 3 in lieu of all or a portion of such Pre-Funded Warrants and accompanying Common Warrants contemplated to be sold under
this Agreement.
The several Underwriters propose
to offer the Securities for sale upon the terms and conditions set forth in the Prospectus. The Company acknowledges and agrees that the
Underwriters may offer and sell Securities to or through any affiliate of an Underwriter.
4. Further
Agreements Of The Company. The Company agrees with the several Underwriters:
(a) Required
Filings; Amendments or Supplements; Notice to the Representative. To prepare the Rule 462(b) Registration Statement, if
necessary, in a form approved by the Representatives and file such Rule 462(b) Registration Statement with the Commission by
10:00 P.M., New York time, on the date hereof, and the Company shall at the time of filing either pay to the Commission the filing fee
for the Rule 462(b) Registration Statement or give irrevocable instructions for the payment of such fee pursuant to Rule 111(b) under
the Rules and Regulations; to prepare the Prospectus in a form approved by the Representatives containing information previously
omitted at the time of effectiveness of the Registration Statement in reliance on Rules 430A or 430B of the Rules and Regulations
and to file such Prospectus pursuant to Rule 424(b) of the Rules and Regulations not later than the second business (2nd)
day following the execution and delivery of this Agreement or, if applicable, such earlier time as may be required by the Securities Act;
to notify the Representatives immediately of the Company’s intention to file or prepare any supplement or amendment to the Registration
Statement or to the Prospectus and to make no amendment or supplement to the Registration Statement, the General Disclosure Package or
to the Prospectus to which the Representatives shall reasonably object by notice to the Company after a reasonable period to review; to
advise the Representatives, promptly after it receives notice thereof, of the time when any amendment to the Registration Statement has
been filed or becomes effective or any supplement to the General Disclosure Package or the Prospectus or any amended Prospectus or any
Issuer Free Writing Prospectus or any Written Testing-the-Waters Communication has been filed and to furnish the Underwriters with copies
thereof; to file promptly all material required to be filed by the Company with the Commission pursuant to Rules 433(d) or 163(b)(2) of
the Rules and Regulations, as the case may be; to file promptly all reports and any definitive proxy or information statements required
to be filed by the Company with the Commission pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act subsequent
to the date of the Prospectus and for so long as the delivery of a prospectus (or in lieu thereof, the notice referred to in Rule 173(a) of
the Rules and Regulations) is required in connection with the offering or sale of the Securities; to advise the Representatives,
promptly after it receives notice thereof, of the issuance by the Commission of any stop order or of any order preventing or suspending
the use of any Issuer Free Writing Prospectus, the Prospectus or any Written Testing-the-Waters Communication, of the suspension of the
qualification of the Securities for offering or sale in any jurisdiction, of the initiation or threatening of any proceeding for any such
purpose, or of any request by the Commission for the amending or supplementing of the Registration Statement, the General Disclosure Package
or the Prospectus or for additional information including, but not limited to, any request for information concerning any Testing-the-Waters
Communication; and, in the event of the issuance of any stop order or of any order preventing or suspending the use of any Issuer Free
Writing Prospectus or the Prospectus or suspending any such qualification, and promptly to use its best efforts to obtain the withdrawal
of such order.
18
(b) Emerging
Growth Company. The Company will promptly notify the Representatives if the Company ceases to be an Emerging Growth Company at any
time prior to the later of (a) the completion of the distribution of the Firm Stock, Common Warrants and Pre-Funded Warrants within
the meaning of the Securities Act and (b) completion of the Lock-Up Period (as defined below). If at any time following the distribution
of any Written Testing-the-Waters Communication there occurred or occurs an event or development as a result of which such Written Testing-the-Waters
Communication included or would include an untrue statement of a material fact or omitted or would omit to state a material fact necessary
in order to make the statements therein, in the light of the circumstances existing at that subsequent time, not misleading, the Company
will promptly notify the Representatives and will promptly amend or supplement, at its own expense, such Written Testing-the-Waters Communication
to eliminate or correct such untrue statement or omission.
(c) Permitted
Free Writing Prospectus. The Company represents and agrees that, unless it obtains the prior consent of the Representatives, and each
Underwriter represents and agrees that, unless it obtains the prior consent of the Company and the Representatives, it has not made and
will not make any offer relating to the Securities that would constitute a “free writing prospectus” as defined in Rule 405
of the Rules and Regulations unless the prior written consent of the Representatives has been received (each, a “Permitted
Free Writing Prospectus”); provided that the prior written consent of the Representatives hereto shall be deemed to have
been given in respect of the Issuer Free Writing Prospectuses included in Schedule B hereto. The Company represents that it has treated
and agrees that it will treat each Permitted Free Writing Prospectus as an Issuer Free Writing Prospectus, comply with the requirements
of Rules 164 and 433 of the Rules and Regulations applicable to any Issuer Free Writing Prospectus, including the requirements
relating to timely filing with the Commission, legending and record keeping and will not take any action that would result in an Underwriter
or the Company being required to file with the Commission pursuant to Rule 433(d) of the Rules and Regulations a free writing
prospectus prepared by or on behalf of such Underwriter that such Underwriter otherwise would not have been required to file thereunder.
19
(d) Ongoing
Compliance. If at any time prior to the date when a prospectus relating to the Securities is required to be delivered (or in lieu
thereof, the notice referred to in Rule 173(a) under the Securities Act) any event occurs or condition exists as a result of
which the Prospectus as then amended or supplemented would include any untrue statement of a material fact, or omit to state any material
fact necessary to make the statements therein, in the light of the circumstances under which they were made when the Prospectus is delivered
(or in lieu thereof, the notice referred to in Rule 173(a) of the Rules and Regulations), not misleading, or if it is necessary
at any time to amend or supplement the Registration Statement or the Prospectus or to file under the Exchange Act any document incorporated
by reference in the Prospectus to comply with the Securities Act or the Exchange Act, that the Company will promptly notify the Representatives
thereof and upon their request will prepare an appropriate amendment or supplement or upon their request make an appropriate filing pursuant
to Section 13 or 14 of the Exchange Act in form and substance satisfactory to the Representatives which will correct such statement
or omission or effect such compliance and will use its reasonable best efforts to have any amendment to the Registration Statement declared
effective as soon as possible. The Company will furnish without charge to each Underwriter and to any dealer in securities as many copies
as the Representatives may from time to time reasonably request of such amendment or supplement. In case any Underwriter is required to
deliver a prospectus (or in lieu thereof, the notice referred to in Rule 173(a) of the Rules and Regulations) relating
to the Securities, the Company upon the request of the Representatives will prepare promptly an amended or supplemented Prospectus as
may be necessary to permit compliance with the requirements of Section 10(a)(3) of the Securities Act and deliver to such Underwriter
as many copies as such Underwriter may request of such amended or supplemented Prospectus complying with Section 10(a)(3) of
the Securities Act.
(e) Amendment
to General Disclosure Package. If the General Disclosure Package is being used to solicit offers to buy the Securities at a time when
the Prospectus is not yet available to prospective purchasers and any event shall occur as a result of which, in the judgment of the Company
or in the reasonable opinion of the Underwriters, it becomes necessary to amend or supplement the General Disclosure Package in order
to make the statements therein, in the light of the circumstances then prevailing, not misleading, or to make the statements therein not
conflict with the information contained or incorporated by reference in the Registration Statement then on file and not superseded or
modified, or if it is necessary at any time to amend or supplement the General Disclosure Package to comply with any law, the Company
promptly will either (i) prepare, file with the Commission (if required) and furnish to the Underwriters and any dealers an appropriate
amendment or supplement to the General Disclosure Package or (ii) prepare and file with the Commission an appropriate filing under
the Exchange Act which shall be incorporated by reference in the General Disclosure Package so that the General Disclosure Package as
so amended or supplemented will not, in the light of the circumstances then prevailing, be misleading or conflict with the Registration
Statement then on file, or so that the General Disclosure Package will comply with law.
(f) Amendment
to Issuer Free Writing Prospectus. If at any time following issuance of an Issuer Free Writing Prospectus there occurred or occurs
an event or development as a result of which such Issuer Free Writing Prospectus conflicted or will conflict with the information contained
in the Registration Statement, Pricing Prospectus or Prospectus, including any document incorporated by reference therein and any prospectus
supplement deemed to be a part thereof, and not superseded or modified or included or would include an untrue statement of a material
fact or omitted or would omit to state a material fact required to be stated therein or necessary in order to make the statements therein,
in the light of the circumstances prevailing at the subsequent time, not misleading, the Company has promptly notified or will promptly
notify the Representatives so that any use of the Issuer Free Writing Prospectus may cease until it is amended or supplemented and the
Company has promptly amended or will promptly amend or supplement, at its own expense, such Issuer Free Writing Prospectus to eliminate
or correct such conflict, untrue statement or omission. The foregoing sentence does not apply to statements in or omissions from any Issuer
Free Writing Prospectus in reliance upon, and in conformity with, written information furnished to the Company through the Representatives
by or on behalf of any Underwriter specifically for inclusion therein, which information the parties hereto agree is limited to the Underwriters’
Information.
20
(g) Delivery
of Registration Statement. To the extent not available on the Commission’s Electronic Data Gathering, Analysis and Retrieval
system or any successor system (“EDGAR”), upon the request of the Representatives, to furnish promptly to the
Representatives and to counsel for the Underwriters a signed copy of the Registration Statement as originally filed with the Commission,
and of each amendment thereto filed with the Commission, including all consents and exhibits filed therewith.
(h) Delivery
of Copies. Upon request of the Representatives, to the extent not available on EDGAR, to deliver promptly to the Representatives in
New York City such number of the following documents as the Representatives shall reasonably request: (i) conformed copies of the
Registration Statement as originally filed with the Commission (in each case excluding exhibits), (ii) any Issuer Free Writing Prospectus,
(iii) the Prospectus (the delivery of the documents referred to in clauses (i), (ii) and (iii) of this paragraph (h) to
be made not later than 10:00 A.M., New York time, on the business day following the execution and delivery of this Agreement), (iv) conformed
copies of any amendment to the Registration Statement (excluding exhibits), (v) any amendment or supplement to the General Disclosure
Package or the Prospectus, and (vi) any document incorporated by reference in the General Disclosure Package or the Prospectus (excluding
exhibits thereto) (the delivery of the documents referred to in clauses (iv), (v) and (vi) of this paragraph (h) to be
made not later than 10:00 A.M., New York City time, on the business day following the date of such document, amendment or supplement).
(i) Earnings
Statement. To make generally available to the Company’s stockholders as soon as practicable, but in any event not later than
sixteen (16) months after the effective date of the Registration Statement (as defined in Rule 158(c) of the Rules and
Regulations), an earnings statement of the Company and its consolidated subsidiaries (which need not be audited) complying with Section 11(a) of
the Securities Act (including, at the option of the Company, Rule 158).
(j) Blue
Sky Compliance. To take promptly from time to time such actions as the Representatives may reasonably request to qualify the Securities
for offering and sale under the securities or Blue Sky laws of such jurisdictions (domestic or foreign) as the Representatives may reasonably
designate and to continue such qualifications in effect, and to comply with such laws, for so long as required to permit the offer and
sale of the Securities in such jurisdictions; provided that the Company and its subsidiaries shall not be obligated to (i) qualify
as foreign corporations in any jurisdiction in which they are not so qualified, (ii) file a general consent to service of process
in any jurisdiction or (iii) subject itself to taxation in any such jurisdiction if it is not otherwise so subject.
(k) Reports.
Upon request, during the period of five (5) years from the date hereof, to deliver to each of the Underwriters, (i) as soon
as they are available, copies of all reports or other communications (financial or other) furnished to the Company’s stockholders,
and (ii) as soon as they are available, copies of any reports and financial statements furnished or filed with the Commission or
any national securities exchange on which the Firm Stock, the Common Warrant Shares and Pre-Funded Warrant Shares are listed. However,
so long as the Company is subject to the reporting requirements of either Section 13 or Section 15(d) of the Exchange Act
and is timely filing reports on EDGAR, it is not required to furnish such reports or statements to the Underwriters.
21
(l) Lock-Up.
During the period commencing on and including the date hereof and ending on and including the 60th day following the date of
this Agreement, (the “Lock-Up Period”) the Company will not, without the prior written consent of the Representatives
(which consent may be withheld at the sole discretion of the Representatives), directly or indirectly offer, sell (including, without
limitation, any short sale), assign, transfer, pledge, contract to sell, establish an open “put equivalent position” within
the meaning of Rule 16a-1(h) under the Exchange Act, or otherwise dispose of, or announce the offering of, or submit or file
any registration statement under the Securities Act in respect of, any Common Stock, options, rights or warrants to acquire Common Stock
or securities exchangeable or exercisable for or convertible into Common Stock (other than is contemplated by this Agreement with respect
to the Securities) or publicly announce any intention to do any of the foregoing; provided, however, that the Company may (i) issue
Common Stock, restricted stock unit and options to purchase Common Stock, shares of Common Stock underlying restricted stock units and
options granted and other securities, each pursuant to any director or employee incentive award plan, stock ownership plan or dividend
reinvestment plan of the Company in effect on the date hereof and described in the General Disclosure Package; (ii) issue Common
Stock pursuant to the conversion of securities or the exercise of warrants, which securities or warrants are outstanding on the date hereof
and described in the General Disclosure Package or the Common Warrants or Pre-Funded Warrants; (iii) issue shares of Common Stock
pursuant to the Sales Agreement, dated December 15, 2023 (the “ATM”), by and between the Company and Cowen and
Company, LLC after forty-five (45) days following the date of this Agreement, provided further, that in the event the closing price of
the Company’s Common Stock the Exchange exceeds $3.85, the Company may issue shares of Common Stock in the ATM; (iv) adopt
a new equity incentive plan, and file a registration statement on Form S-8 under the Securities Act to register the offer and sale
of securities to be issued pursuant to such new equity incentive plan, and issue securities pursuant to such new equity incentive plan
(including, without limitation, the issuance of shares of Common Stock upon the exercise of options or other securities issued pursuant
to such new equity incentive plan), provided that (A) such new equity incentive plan satisfies the transaction requirements
of General Instruction A.1 of Form S-8 under the Securities Act and (B) this clause (iv) shall not be available unless
each recipient if such person is an officer or director of the Company, of shares of Common Stock, or securities exchangeable or exercisable
for or convertible into Common Stock, pursuant to such new equity incentive plan shall be contractually prohibited from selling, offering,
disposing of or otherwise transferring any such shares or securities during the remainder of the Lock-Up Period; (v) facilitate the
transfer of shares of Common Stock under a trading plan pursuant to Rule 10b5-1 under the Exchange Act (a “Trading Plan”)
that is existing on the date hereof which has been provided to the Representatives or their legal counsel, (vi) facilitate the establishment
of a trading plan on behalf of a shareholder, officer or director of the Company pursuant to Rule 10b5-1 under the Exchange Act for
the transfer of Common Stock, provided that (A) such plan does not provide for the transfer of Common Stock during the Lock-Up Period
and (B) to the extent a public announcement or filing under the Exchange Act, if any, is required of or voluntarily made by the Company
regarding the establishment of such plan, such announcement or filing shall include a statement to the effect that no transfer of Common
Stock may be made under such plan during the Lock-Up Period and (vii) effect the offering and sale of common stock pursuant to the
concurrent registered direct offering described in each of the Registration Statement, the General Disclosure Package and the Prospectus.
The Company will cause each person and entity listed in Schedule D to furnish to the Representatives, prior to the Closing Date,
a “lock-up” agreement, substantially in the form of Exhibit I hereto. In addition, the Company will direct the
transfer agent to place stop transfer restrictions upon any such securities of the Company that are bound by such “lock-up”
agreements. During the period commencing on and including the date hereof and ending on and including the earlier of (x) 180th
day following the date of this Agreement and (y) the date that none of the Common Warrants are outstanding, the Company shall be
prohibited from effecting or entering into an agreement to effect any “Variable Rate Transaction.” The term “Variable
Rate Transaction” shall mean a transaction in which the Company (i) issues or sells any debt or equity securities that are
convertible into, exchangeable or exercisable for, or include the right to receive additional shares of Common Stock either (A) at
a conversion, exercise or exchange rate or other price that is based upon and/or varies with the trading prices of or quotations for the
shares of Common Stock at any time after the initial issuance of such debt or equity securities, or (B) with a conversion, exercise
or exchange price that is subject to being reset at some future date after the initial issuance of such debt or equity security or upon
the occurrence of specified or contingent events directly or indirectly related to the business of the Company or the market for the Common
Stock or (ii) enters into any agreement, including, but not limited to, an equity line of credit, whereby the Company may sell securities
at a future determined price. For the avoidance of doubt, the issuance of a security which is subject to customary anti-dilution protections,
including where the conversion, exercise or exchange price is subject to adjustment as a result of stock splits, reverse stock splits
and other similar recapitalization or reclassification events, shall not be deemed to be a “Variable Rate Transaction.” For
the further avoidance of doubt, “Variable Rate Transaction” does not include the issuance of revenue bonds or other straight
debt instruments with no equity or equity-linked components, traditional term loans or credit facilities that do not include equity or
equity-linked conversion features, or the ATM.
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(m) Delivery
of SEC Correspondence. To supply the Underwriters with copies of all correspondence to and from, and all documents issued to and by,
the Commission in connection with the registration of the Securities under the Securities Act or any of the Registration Statement, or
the Prospectus, or any amendment or supplement thereto or document incorporated by reference therein.
(n) Press
Releases. Prior to the Closing Date, not to issue any press release or other communication directly or indirectly or hold any press
conference with respect to the Company, its condition, financial or otherwise, or earnings, business affairs or business prospects (except
for routine oral marketing communications in the ordinary course of business and consistent with the past practices of the Company and
of which the Representatives are notified), without the prior consent of the Representatives, unless in the judgment of the Company and
its counsel, and after notification to the Representatives, such press release or communication is required by law.
(o) Compliance
with Regulation M. Until the Underwriters shall have notified the Company of the completion of the resale of the Securities, that
the Company will not, and will use its reasonable best efforts to cause its affiliated purchasers (as defined in Regulation M under the
Exchange Act) not to, either alone or with one or more other persons, bid for or purchase, for any account in which it or any of its affiliated
purchasers has a beneficial interest, any Securities, or attempt to induce any person to purchase any Securities; and not to, and to use
its reasonable best efforts to cause its affiliated purchasers not to, make bids or purchase for the purpose of creating actual, or apparent,
active trading in or of raising the price of the Securities.
(p) Registrar,
Transfer Agent and Warrant Agent. To maintain, at its expense, a registrar and transfer agent for the Firm Stock, Common Warrant Shares
and Pre-Funded Warrant Shares, and a warrant agent, which shall initially be the Company, for the Common Warrants and Pre-Funded Warrants.
(q) Use
of Proceeds. To apply the net proceeds from the sale of the Securities as set forth in the Registration Statement, the General Disclosure
Package and the Prospectus under the heading “Use of Proceeds,” and except as disclosed in the General Disclosure Package,
the Company does not intend to use any of the proceeds from the sale of the Securities hereunder to repay any outstanding debt owed to
any affiliate of any Underwriter.
(r) Exchange
Listing. To use its reasonable best efforts to list, subject to notice of issuance, the Firm Stock, the Common Warrant Shares and
Pre-Funded Warrant Shares on the Nasdaq Capital Market (the “Exchange”).
(s) Performance
of Covenants and Satisfaction of Conditions. To use its reasonable best efforts to do and perform all things required to be done or
performed under this Agreement by the Company prior to each Closing Date and to satisfy all conditions precedent to the delivery of the
Firm Stock, Common Warrants and the Pre-Funded Warrants.
(t) Reservation
of Pre-Funded Warrant Shares and Common Warrant Shares. The Company shall, at all times while any Pre-Funded Warrants or Common Warrants
are outstanding, reserve and keep available out of the aggregate of its authorized but unissued and otherwise unreserved Common Shares,
solely for the purpose of enabling it to issue Pre-Funded Warrant Shares and Common Warrant Shares upon exercise of such warrants, the
number of Pre-Funded Warrant Shares and Common Warrant Shares that are initially issuable and deliverable upon the exercise of the then-outstanding
Pre-Funded Warrants and Common Warrants.
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5. Payment
of Expenses. The Company agrees to pay, or reimburse if paid by any Underwriter, whether or not the transactions contemplated
hereby are consummated or this Agreement is terminated: (a) the costs incident to the authorization, issuance, sale, preparation
and delivery of the Securities and any taxes payable in that connection; (b) the costs incident to the registration of the Securities
under the Securities Act; (c) the costs incident to the preparation, printing and distribution of the Registration Statement, any
Issuer Free Writing Prospectus, the General Disclosure Package, the Prospectus, any amendments, supplements and exhibits thereto or any
document incorporated by reference therein and the costs of printing, reproducing and distributing the “Agreement Among Underwriters”
between the Representatives and the Underwriters, the Master Selected Dealers’ Agreement, the Underwriters’ Questionnaire,
this Agreement and any closing documents by mail, telex or other means of communications; (d) the fees and expenses (including related
fees and expenses of counsel for the Underwriters) incurred in connection with determining the compliance of this offering with FINRA’s
rules and securing any required review by FINRA of the terms of the sale of the Securities and any filings made with FINRA (the “FINRA
Expenses”); (e) any applicable listing or other fees; (f) the fees and expenses (including the reasonable and documented
fees and expenses of counsel to the Underwriters related thereto) of qualifying the Securities under the securities laws of the several
jurisdictions as provided in Section 4(j) and of preparing, printing and distributing wrappers, Blue Sky Memoranda and Legal
Investment Surveys; (g) the cost of preparing and printing stock certificates; (h) all fees and expenses of the registrar and
transfer agent of the Firm Stock, Common Warrant Shares and Pre-Funded Warrant Shares; (i) the fees, disbursements and expenses of
counsel to the Underwriters(inclusive of the FINRA Expenses) up to an aggregate of $100,000; (j) costs and expenses of the Company
relating to investor presentations on any “road show” undertaken in connection with the marketing of the offering of the Securities,
including, without limitation, expenses associated with the preparation or dissemination of any electronic road show, expenses associated
with the production of road show slides and graphics, fees and expenses of any consultants engaged in connection with the road show presentations
with the prior approval of the Company, travel and lodging expenses of the officers of the Company and such consultants, including the
cost of any aircraft chartered in connection with the road show; (k) the costs of reproducing and distributing each of the Common
Warrants and Pre-Funded Warrants; and (l) all other costs and expenses incident to the offering of the Securities or the performance
of the obligations of the Company under this Agreement (including, without limitation, the fees and expenses of the Company’s counsel
and the Company’s independent accountants); provided that, except to the extent otherwise provided in this Section 5
and in Sections 9 and 10, the Underwriters shall pay their own costs and expenses, including the fees and expenses of their counsel not
contemplated herein, any transfer taxes on the resale of any Securities by them and the expenses of advertising any offering of the Securities
made by the Underwriters.
6. Conditions
of Underwriters’ Obligations. The respective obligations of the several Underwriters hereunder are subject to the accuracy,
when made and as of the Applicable Time and on each Closing Date, of the representations and warranties of the Company contained herein,
to the accuracy of the statements of the Company made in any certificates pursuant to the provisions hereof, to the performance by the
Company of its obligations hereunder, and to each of the following additional terms and conditions:
(a) Registration
Compliance; No Stop Orders. The Registration Statement has become effective under the Securities Act, and no stop order suspending
the effectiveness of the Registration Statement or any part thereof, preventing or suspending the use of the Prospectus or any Permitted
Free Writing Prospectus or any part thereof shall have been issued and no proceedings for that purpose or pursuant to Section 8A
under the Securities Act shall have been initiated or threatened by the Commission, and all requests for additional information on the
part of the Commission (to be included or incorporated by reference in the Registration Statement or the Prospectus or otherwise) shall
have been complied with to the reasonable satisfaction of the Representatives; the Rule 462(b) Registration Statement, if any,
each Issuer Free Writing Prospectus and the Prospectus shall have been filed with, the Commission within the applicable time period prescribed
for such filing by, and in compliance with, the Rules and Regulations and in accordance with Section 4(a), and the Rule 462(b) Registration
Statement, if any, shall have become effective immediately upon its filing with the Commission; and FINRA shall have raised no unresolved
objection to the fairness and reasonableness of the terms of this Agreement or the transactions contemplated hereby.
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(b) No
Material Misstatements. None of the Underwriters shall have discovered and disclosed to the Company on or prior to such Closing Date
that the Registration Statement or any amendment or supplement thereto contains an untrue statement of a fact which, in the opinion of
counsel for the Underwriters, is material or omits to state any fact which, in the opinion of such counsel, is material and is required
to be stated therein or is necessary to make the statements therein not misleading, or that the General Disclosure Package, any Issuer
Free Writing Prospectus or the Prospectus or any amendment or supplement thereto contains an untrue statement of fact which, in the opinion
of such counsel, is material or omits to state any fact which, in the opinion of such counsel, is material and is necessary in order to
make the statements, in the light of the circumstances in which they were made, not misleading.
(c) Corporate
Proceedings. All corporate proceedings incident to the authorization, form and validity of each of this Agreement, the Securities,
the Registration Statement, the General Disclosure Package, each Issuer Free Writing Prospectus and the Prospectus and the transactions
contemplated hereby shall be reasonably satisfactory in all material respects to counsel for the Underwriters and the Company shall have
furnished to such counsel all documents and information that they may reasonably request to enable them to pass upon such matters.
(d) Opinion
and 10b-5 Statement of Counsel for the Company. Goodwin Procter LLP shall have furnished to the Representatives such counsel’s
written opinion and 10b-5 statement, as counsel to the Company, addressed to the Underwriters and dated such Closing Date, in form and
substance reasonably satisfactory to the Representatives.
(e) Opinion
of Intellectual Property Counsel for the Company. Goodwin Procter LLP shall have furnished to the Representatives such counsel’s
written opinion, as intellectual property counsel to the Company, addressed to the Underwriters and dated such Closing Date, in form and
substance reasonably satisfactory to the Representatives.
(f) Opinion
and 10b-5 Statement of Counsel for the Underwriters. The Representatives shall have received from Covington & Burling LLP,
counsel for the Underwriters, such opinion or opinions and 10b-5 statement, dated such Closing Date, with respect to such matters as the
Underwriters may reasonably require, and the Company shall have furnished to such counsel such documents as they request for enabling
them to pass upon such matters.
(g) Comfort
Letter. At the time of the execution of this Agreement, the Representatives shall have received from PricewaterhouseCoopers LLP a
letter, addressed to the Underwriters, executed and dated such date, in form and substance satisfactory to the Representatives (i) confirming
that they are an independent registered accounting firm with respect to the Company and its subsidiaries within the meaning of the Securities
Act and the Rules and Regulations and PCAOB and (ii) stating the conclusions and findings of such firm, of the type ordinarily
included in accountants’ “comfort letters” to underwriters, with respect to the financial statements and certain financial
information contained or incorporated by reference in the Registration Statement, the General Disclosure Package and the Prospectus.
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(h) Bring
Down Comfort. On the effective date of any post-effective amendment to the Registration Statement and on such Closing Date, the Representatives
shall have received a letter (the “bring-down letter”) from PricewaterhouseCoopers LLP addressed to the Underwriters
and dated such Closing Date confirming, as of the date of such bring-down letter (or, with respect to matters involving changes or developments
since the respective dates as of which specified financial information is given in the General Disclosure Package and the Prospectus,
as the case may be, as of a date not more than three (3) business days prior to the date of the bring-down letter), the conclusions
and findings of such firm, of the type ordinarily included in accountants’ “comfort letters” to underwriters, with respect
to the financial information and other matters covered by its letter delivered to the Representatives concurrently with the execution
of this Agreement pursuant to paragraph (g) of this Section 6.
(i) Officers’
Certificate. The Company shall have furnished to the Representatives a certificate, dated such Closing Date, of the President and
Chief Executive Officer and Chief Financial Officer of the Company stating in their respective capacities as officers of the Company on
behalf of the Company that (i) no stop order suspending the effectiveness of the Registration Statement (including, for avoidance
of doubt, any Rule 462(b) Registration Statement), or any post-effective amendment thereto, shall be in effect and no proceedings
for such purpose shall have been instituted or, to their knowledge, threatened by the Commission, (ii) for the period from and including
the date of this Agreement through and including such Closing Date, there has not occurred any Material Adverse Effect, (iii) to
their knowledge, after reasonable investigation, as of such Closing Date, the representations and warranties of the Company in this Agreement
are true and correct and the Company has complied with all agreements and satisfied all conditions on its part to be performed or satisfied
hereunder at or prior to such Closing Date, and (iv) there has not been, subsequent to the date of the most recent audited financial
statements included or incorporated by reference in the General Disclosure Package, any Material Adverse Effect in the financial position
or results of operations of the Company, or any change or development that would, singularly or in the aggregate, reasonably be expected
to have a Material Adverse Effect, except as set forth in the General Disclosure Package and the Prospectus.
(j) No
Material Adverse Effect. Since the date of the latest audited financial statements included in the General Disclosure Package or incorporated
by reference in the General Disclosure Package as of the date hereof, (i) neither the Company nor any of its subsidiaries shall have
sustained any loss or interference with its business from fire, explosion, flood or other calamity, whether or not covered by insurance,
or from any labor dispute or court or governmental action, order or decree, otherwise than as set forth in the General Disclosure Package,
and (ii) there shall not have been any change in the capital stock or long-term debt of the Company or any of its subsidiaries, or
any change, or any development involving a prospective change, in or affecting the business, general affairs, management, financial position,
stockholders’ equity or results of operations of the Company and its subsidiaries, otherwise than as set forth in the General Disclosure
Package, the effect of which, in any such case described in clause (i) or (ii) of this paragraph (j), is, in the judgment of
the Representatives, so material and adverse as to make it impracticable or inadvisable to proceed with the sale or delivery of the Securities
on the terms and in the manner contemplated in the General Disclosure Package.
(k) No
Legal Impediment to Issuance. No action shall have been taken and no law, statute, rule, regulation or order shall have been enacted,
adopted or issued by any governmental or regulatory agency or body which would prevent the issuance or sale of the Securities; and no
injunction, restraining order or order of any other nature by any federal or state court of competent jurisdiction shall have been issued
which would prevent the issuance or sale of the Securities or materially and adversely affect or potentially materially and adversely
affect the business or operations of the Company.
26
(l) Market
Conditions. Subsequent to the execution and delivery of this Agreement there shall not have occurred any of the following: (i) other
than in connection with the offering and sale of the Securities, trading in any of the securities of the Company shall have been suspended
or materially limited by the Commission or the Exchange, or trading in securities generally on the New York Stock Exchange, Nasdaq Global
Select Market, Nasdaq Global Market, the Exchange, or the NYSE MKT LLC, or in the over-the-counter market, or trading in any securities
of the Company on any exchange or in the over-the-counter market, shall have been suspended or materially limited, or minimum or maximum
prices or maximum range for prices shall have been established on any such exchange or such market by the Commission, by such exchange
or market or by any other regulatory body or governmental authority having jurisdiction, (ii) a banking moratorium shall have been
declared by Federal or state authorities or a material disruption has occurred in commercial banking or securities settlement or clearance
services in the United States, (iii) the United States shall have become engaged in hostilities, or the subject of an act of terrorism,
or there shall have been an outbreak of or escalation in hostilities involving the United States, or there shall have been a declaration
of a national emergency or war by the United States or (iv) there shall have occurred such a material adverse change in general economic,
political or financial conditions (or the effect of international conditions on the financial markets in the United States shall be such)
as to make it, in the judgment of the Representatives, impracticable or inadvisable to proceed with the sale or delivery of the Securities
on the terms and in the manner contemplated in the General Disclosure Package and the Prospectus.
(m) Exchange
Listing. The Company shall have filed a Notification: Listing of Additional Shares with the Exchange in respect of the Firm Stock,
the Common Warrant Shares and the Pre-Funded Warrant Shares and shall have received no objection thereto from the Exchange.
(n) Good
Standing. The Representatives shall have received on and as of such Closing Date satisfactory evidence of the good standing of the
Company and its subsidiaries in their respective jurisdictions of organization and their good standing as foreign entities in such other
jurisdictions as the Representatives may reasonably request, in each case in writing or any standard form of telecommunication from the
appropriate governmental authorities of such jurisdictions.
(o) Lock
Up Agreements. The Representatives shall have received the written agreements, substantially in the form of Exhibit I
hereto, of the persons listed in Schedule D to this Agreement.
(p) Secretary’s
Certificate. The Company shall have furnished to the Representatives a Secretary’s Certificate of the Company, in form and substance
reasonably satisfactory to counsel for the Underwriters and customary for the type of offering contemplated by this Agreement.
(q) Chief
Financial Officer Certificate. The Company shall have furnished to the Representatives a certificate, dated such Closing Date, of
its Chief Financial Officer, substantially in the form of Exhibit II hereto.
(r) Additional
Documents. On or prior to such Closing Date, the Company shall have furnished to the Representatives such further certificates and
documents as the Representatives may reasonably request.
(s) Form of
Pre-Funded Warrants and Common Warrants. On or prior to such Closing Date, evidence of the Pre-Funded Warrants and Common Warrants
shall be delivered to those persons and entities as directed by the Representatives in the form and substance reasonably acceptable the
Representatives, including to reflect such names and in such denomination as the Representatives directed pursuant to Section 3.
All opinions, letters, evidence
and certificates mentioned above or elsewhere in this Agreement shall be deemed to be in compliance with the provisions hereof only if
they are in form and substance reasonably satisfactory to counsel for the Underwriters.
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7. Indemnification
and Contribution.
(a) Indemnification
of Underwriters by the Company. The Company shall indemnify and hold harmless: each Underwriter, its affiliates, directors, officers,
managers, members, employees, representatives and agents and each person, if any, who controls any Underwriter within the meaning of Section 15
of the Securities Act or Section 20 of the Exchange Act (collectively the “Underwriter Indemnified Parties,”
and each an “Underwriter Indemnified Party”) against any loss, claim, damage, expense or liability whatsoever
(or any action, investigation or proceeding in respect thereof), joint or several, to which such Underwriter Indemnified Party may become
subject, under the Securities Act or otherwise, insofar as such loss, claim, damage, expense, liability, action, investigation or proceeding
arises out of or is based upon (A) any untrue statement or alleged untrue statement of a material fact contained in any Written Testing-the-Waters
Communication, any Issuer Free Writing Prospectus, any “issuer information” filed or required to be filed pursuant to Rule 433(d) of
the Rules and Regulations, the Registration Statement, the Prospectus, or in any amendment or supplement thereto, in any document
incorporated by reference therein, or in any materials or information provided to investors by, or with the approval of, the Company in
connection with the marketing of the offering of the Securities, including any roadshow or investor presentations made to investors by
the Company (whether in person or electronically) (“Marketing Materials”), or (B) the omission or alleged
omission to state in any Issuer Free Writing Prospectus, any “issuer information” filed or required to be filed pursuant to
Rule 433(d) of the Rules and Regulations, the Registration Statement or the Prospectus, or in any amendment or supplement
thereto or document incorporated by reference therein, or in any Marketing Materials, a material fact required to be stated therein or
necessary to make the statements therein not misleading; and shall reimburse each Underwriter Indemnified Party promptly upon demand for
any reasonable and documented legal fees or other expenses reasonably incurred by that Underwriter Indemnified Party in connection with
investigating, or preparing to defend, or defending against, or appearing as a third party witness in respect of, or otherwise incurred
in connection with, any such loss, claim, damage, expense, liability, action, investigation or proceeding, as such fees and expenses are
incurred; provided, however, that the Company shall not be liable in any such case to the extent that any such loss, claim,
damage, expense or liability arises out of or is based upon an untrue statement or alleged untrue statement in, or omission or alleged
omission from the Registration Statement or the Prospectus, or any such amendment or supplement thereto, any Issuer Free Writing Prospectus
or any Marketing Materials made in reliance upon and in conformity with written information furnished to the Company through the Representatives
by or on behalf of any Underwriter specifically for use therein, which information the parties hereto agree is limited to the Underwriters’
Information.
The indemnity agreement in this Section 7(a) is
not exclusive and is in addition to each other liability which the Company might have under this Agreement or otherwise, and shall not
limit any rights or remedies which may otherwise be available under this Agreement, at law or in equity to any Underwriter Indemnified
Party.
(b) Indemnification
of Company by the Underwriters. Each Underwriter, severally and not jointly, shall indemnify and hold harmless the Company and its
directors, its officers who signed the Registration Statement and each person, if any, who controls the Company within the meaning of
Section 15 of the Securities Act or Section 20 of the Exchange Act (collectively the “Company Indemnified Parties”
and each a “Company Indemnified Party”) against any loss, claim, damage, expense or liability whatsoever (or
any action, investigation or proceeding in respect thereof), joint or several, to which such Company Indemnified Party may become subject,
under the Securities Act or otherwise, insofar as such loss, claim, damage, expense, liability, action, investigation or proceeding arises
out of or is based upon (i) any untrue statement or alleged untrue statement of a material fact contained in any Issuer Free Writing
Prospectus, any “issuer information” filed or required to be filed pursuant to Rule 433(d) of the Rules and
Regulations, the Registration Statement or the Prospectus, or in any amendment or supplement thereto, or (ii) the omission or alleged
omission to state in any Issuer Free Writing Prospectus, any “issuer information” filed or required to be filed pursuant to
Rule 433(d) of the Rules and Regulations, the Registration Statement or the Prospectus, or in any amendment or supplement
thereto, a material fact required to be stated therein or necessary to make the statements therein not misleading, but in each case only
to the extent that the untrue statement or alleged untrue statement or omission or alleged omission was made in reliance upon and in conformity
with written information furnished to the Company through the Representatives by or on behalf of that Underwriter specifically for use
therein, which information the parties hereto agree is limited to the Underwriters’ Information, and shall reimburse the Company
Indemnified Parties for any reasonable and documented legal or other expenses reasonably incurred by such party in connection with investigating
or preparing to defend or defending against or appearing as third party witness in connection with any such loss, claim, damage, liability,
action, investigation or proceeding, as such fees and expenses are incurred. This indemnity agreement is not exclusive and will be in
addition to any liability which the Underwriters might otherwise have and shall not limit any rights or remedies which may otherwise be
available under this Agreement, at law or in equity to the Company Indemnified Parties.
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(c) Promptly
after receipt by an indemnified party under this Section 7 of notice of the commencement of any action, the indemnified party shall,
if a claim in respect thereof is to be made against an indemnifying party under this Section 7, notify such indemnifying party in
writing of the commencement of that action; provided, however, that the failure to notify the indemnifying party shall not relieve
it from any liability which it may have under this Section 7 except to the extent it has been materially prejudiced by such failure;
and, provided, further, that the failure to notify an indemnifying party shall not relieve it from any liability which it may have
to an indemnified party otherwise than under this Section 7. If any such action shall be brought against an indemnified party, and
it shall notify the indemnifying party thereof, the indemnifying party shall be entitled to participate therein and, to the extent that
it wishes, jointly with any other similarly notified indemnifying party, to assume the defense of such action with counsel reasonably
satisfactory to the indemnified party (which counsel shall not, except with the written consent of the indemnified party, be counsel to
the indemnifying party). After notice from the indemnifying party to the indemnified party of its election to assume the defense of such
action, except as provided herein, the indemnifying party shall not be liable to the indemnified party under Section 7 for any legal
or other expenses subsequently incurred by the indemnified party in connection with the defense of such action other than reasonable costs
of investigation; provided, however, that any indemnified party shall have the right to employ separate counsel in any such action
and to participate in the defense of such action but the fees and expenses of such counsel (other than reasonable costs of investigation)
shall be at the expense of such indemnified party unless (i) the employment thereof has been specifically authorized in writing by
the Company in the case of a claim for indemnification under Section 7(a) or the Representatives in the case of a claim for
indemnification under Section 7(b), (ii) such indemnified party shall have been advised by its counsel that there may be one
or more legal defenses available to it which are different from or additional to those available to the indemnifying party, or (iii) the
indemnifying party has failed to assume the defense of such action and employ counsel reasonably satisfactory to the indemnified party
within a reasonable period of time after notice of the commencement of the action or the indemnifying party does not diligently defend
the action after assumption of the defense, in which case, if such indemnified party notifies the indemnifying party in writing that it
elects to employ separate counsel at the expense of the indemnifying party, the indemnifying party shall not have the right to assume
the defense of (or, in the case of a failure to diligently defend the action after assumption of the defense, to continue to defend) such
action on behalf of such indemnified party and the indemnifying party shall be responsible for legal or other expenses subsequently incurred
by such indemnified party in connection with the defense of such action; provided, however, that the indemnifying party
shall not, in connection with any one such action or separate but substantially similar or related actions in the same jurisdiction arising
out of the same general allegations or circumstances, be liable for the reasonable fees and expenses of more than one separate firm of
attorneys at any time for all such indemnified parties (in addition to any local counsel), which firm shall be designated in writing by
the Representatives if the indemnified parties under this Section 7 consist of any Underwriter Indemnified Party or by the Company
if the indemnified parties under this Section 7 consist of any Company Indemnified Parties. Subject to this Section 7(c), the
amount payable by an indemnifying party under Section 7 shall include, but not be limited to, (x) reasonable and documented
legal fees and expenses of counsel to the indemnified party and any other expenses in investigating, or preparing to defend or defending
against, or appearing as a third party witness in respect of, or otherwise incurred in connection with, any action, investigation, proceeding
or claim, and (y) all amounts paid in settlement of any of the foregoing. No indemnifying party shall, without the prior written
consent of the indemnified parties, settle or compromise or consent to the entry of judgment with respect to any pending or threatened
action or any claim whatsoever, in respect of which indemnification or contribution could be sought under this Section 7 (whether
or not the indemnified parties are actual or potential parties thereto), unless such settlement, compromise or consent (i) includes
an unconditional release of each indemnified party in form and substance reasonably satisfactory to such indemnified party from all liability
arising out of such action or claim and (ii) does not include a statement as to or an admission of fault, culpability or a failure
to act by or on behalf of any indemnified party. Subject to the provisions of the following sentence, no indemnifying party shall be liable
for settlement of any pending or threatened action or any claim whatsoever that is effected without its written consent (which consent
shall not be unreasonably withheld or delayed), but if settled with its written consent, if its consent has been unreasonably withheld
or delayed or if there be a judgment for the plaintiff in any such matter, the indemnifying party agrees to indemnify and hold harmless
any indemnified party from and against any loss or liability by reason of such settlement or judgment. In addition, if at any time an
indemnified party shall have requested that an indemnifying party reimburse the indemnified party for fees and expenses of counsel, such
indemnifying party agrees that it shall be liable for any settlement of the nature contemplated by this Section 7(c) effected
without its written consent if (i) such settlement is entered into more than forty-five (45) days after receipt by such indemnifying
party of the request for reimbursement, (ii) such indemnifying party shall have received notice of the terms of such settlement at
least thirty (30) days prior to such settlement being entered into and (iii) such indemnifying party shall not have reimbursed such
indemnified party in accordance with such request prior to the date of such settlement.
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(d) If
the indemnification provided for in this Section 7 is unavailable or insufficient to hold harmless an indemnified party under Section 7(a) or
7(b), then each indemnifying party shall, in lieu of indemnifying such indemnified party, contribute to the amount paid, payable or otherwise
incurred by such indemnified party as a result of such loss, claim, damage, expense or liability (or any action, investigation or proceeding
in respect thereof), as incurred, (i) in such proportion as shall be appropriate to reflect the relative benefits received by the
Company on the one hand and the Underwriters on the other from the offering of the Securities, or (ii) if the allocation provided
by clause (i) of this Section 7(d) is not permitted by applicable law, in such proportion as is appropriate to reflect
not only the relative benefits referred to in clause (i) of this Section 7(d) but also the relative fault of the Company
on the one hand and the Underwriters on the other with respect to the statements, omissions, acts or failures to act which resulted in
such loss, claim, damage, expense or liability (or any action, investigation or proceeding in respect thereof) as well as any other relevant
equitable considerations. The relative benefits received by the Company on the one hand and the Underwriters on the other with respect
to such offering shall be deemed to be in the same proportion as the total net proceeds from the offering of the Securities purchased
under this Agreement (before deducting expenses) received by the Company bear to the total underwriting discounts and commissions received
by the Underwriters with respect to the Securities purchased under this Agreement, in each case as set forth in the table on the cover
page of the Prospectus. The relative fault of the Company on the one hand and the Underwriters on the other shall be determined by
reference to, among other things, whether the untrue or alleged untrue statement of a material fact or the omission or alleged omission
to state a material fact relates to information supplied by the Company on the one hand or the Underwriters on the other, the intent of
the parties and their relative knowledge, access to information and opportunity to correct or prevent such untrue statement, omission,
act or failure to act; provided that the parties hereto agree that the written information furnished to the Company through the
Representatives by or on behalf of the Underwriters for use in the Registration Statement or the Prospectus, or in any amendment or supplement
thereto, consists solely of the Underwriters’ Information.
(e) The
Company and the Underwriters agree that it would not be just and equitable if contributions pursuant to Section 7(d) above were
to be determined by pro rata allocation or by any other method of allocation which does not take into account the equitable considerations
referred to Section 7(d) above. The amount paid or payable by an indemnified party as a result of the loss, claim, damage, expense,
liability, action, investigation or proceeding referred to in Section 7(d) above shall be deemed to include, subject to the
limitations set forth above, any legal or other expenses reasonably incurred by such indemnified party in connection with investigating,
preparing to defend or defending against or appearing as a third party witness in respect of, or otherwise incurred in connection with,
any such loss, claim, damage, expense, liability, action, investigation or proceeding. Notwithstanding the provisions of this Section 7,
no Underwriter shall be required to contribute any amount in excess of the amount by which the total underwriting discounts and commissions
received by such Underwriter with respect to the offering of the Securities exceeds the amount of any damages which the Underwriter has
otherwise paid or become liable to pay by reason of any untrue or alleged untrue statement, omission or alleged omission, act or alleged
act or failure to act or alleged failure to act. No person guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of
the Securities Act) shall be entitled to contribution from any person who was not guilty of such fraudulent misrepresentation. The Underwriters’
obligations to contribute as provided in this Section 7 are several in proportion to their respective underwriting obligations and
not joint.
8. Termination.
The obligations of the Underwriters hereunder may be terminated by the Representatives, in their absolute discretion by notice given to
the Company prior to delivery of and payment for the Firm Stock, the Common Warrants and the Pre-Funded Warrants if, prior to that time,
any of the events described in Sections 6(j) or 6(l) have occurred or if the Underwriters shall decline to purchase the Firm
Stock, the Common Warrants and the Pre-Funded Warrants for any reason permitted under this Agreement.
9. Reimbursement
of Underwriters’ Expenses. Notwithstanding anything to the contrary in this Agreement, if (a) this Agreement shall
have been terminated pursuant to Section 8 or 10, (b) the Company shall fail to tender the Securities for delivery to the Underwriters,
or in the case of the Pre-Funded Warrants and accompanying Common Warrants, to the purchasers thereof, if applicable, for any reason not
permitted under this Agreement, (c) the Underwriters shall decline to purchase the Securities for any reason permitted under this
Agreement or (d) the sale of the Securities is not consummated because any condition to the obligations of the Underwriters set forth
herein is not satisfied or because of the refusal, inability or failure on the part of the Company to perform any agreement herein or
to satisfy any condition or to comply with the provisions hereof, then in addition to the payment of amounts in accordance with Section 5,
the Company shall reimburse the Underwriters for the fees and expenses of Underwriters’ counsel and for such other out-of-pocket
expenses as shall have been reasonably incurred and documented by them in connection with this Agreement and the proposed purchase of
the Securities, including, without limitation, travel and lodging expenses of the Underwriters, and upon demand the Company shall pay
the full amount thereof to the Representatives; provided that if this Agreement is terminated pursuant to Section 10 by reason
of the default of one or more Underwriters, the Company shall not be obligated to reimburse any defaulting Underwriter on account of expenses
to the extent incurred by such defaulting Underwriter, provided further that the foregoing shall not limit any reimbursement obligation
of the Company to any non-defaulting Underwriter under this Section 9.
30
10. Substitution
of Underwriters. If any Underwriter or Underwriters shall default in its or their obligations to purchase Securities hereunder
on any Closing Date and the aggregate number of Securities which such defaulting Underwriter or Underwriters agreed but failed to purchase
does not exceed ten percent (10%) of the total number of Securities to be purchased by all Underwriters on such Closing Date, the other
Underwriters shall be obligated severally, in proportion to their respective commitments hereunder, to purchase the Securities which such
defaulting Underwriter or Underwriters agreed but failed to purchase on such Closing Date. If any Underwriter or Underwriters shall so
default and the aggregate number of Securities with respect to which such default or defaults occur is more than ten percent (10%) of
the total number of Securities to be purchased by all Underwriters on such Closing Date and arrangements satisfactory to the Representatives
and the Company for the purchase of such Securities by other persons are not made within forty-eight (48) hours after such default, this
Agreement shall terminate.
If the remaining Underwriters
or substituted Underwriters are required hereby or agree to take up all or part of the Securities of a defaulting Underwriter or Underwriters
on such Closing Date as provided in this Section 10, (i) the Company shall have the right to postpone such Closing Date for
a period of not more than five (5) full business days in order that the Company may effect whatever changes may thereby be made necessary
in the Registration Statement or the Prospectus, or in any other documents or arrangements, and the Company agrees promptly to file any
amendments to the Registration Statement or supplements to the Prospectus which may thereby be made necessary, and (ii) the respective
numbers of Securities to be purchased by the remaining Underwriters or substituted Underwriters shall be taken as the basis of their underwriting
obligation for all purposes of this Agreement. Nothing herein contained shall relieve any defaulting Underwriter of its liability to the
Company or the other Underwriters for damages occasioned by its default hereunder. Any termination of this Agreement pursuant to this
Section 10 shall be without liability on the part of any non-defaulting Underwriter or the Company, except that the representations,
warranties, covenants, indemnities, agreements and other statements set forth in Section 2, the obligations with respect to expenses
to be paid or reimbursed pursuant to Sections 5 and 9 and the provisions of Section 7 and Sections 11 through 21, inclusive, shall
not terminate and shall remain in full force and effect.
11. Absence
of Fiduciary Relationship. The Company acknowledges and agrees that:
(a) each
Underwriter’s responsibility to the Company is solely contractual in nature, the Representatives have been retained solely to act
as underwriters in connection with the sale of the Securities and no fiduciary, advisory or agency relationship between the Company and
the Representatives has been created in respect of any of the transactions contemplated by this Agreement, irrespective of whether any
of the Representatives has advised or is advising the Company on other matters;
(b) the
price of the Securities set forth in this Agreement was established by the Company following discussions and arms-length negotiations
with the Representatives, and the Company is capable of evaluating and understanding, and understands and accepts, the terms, risks and
conditions of the transactions contemplated by this Agreement;
(c) it
has been advised that the Representatives and their affiliates are engaged in a broad range of transactions which may involve interests
that differ from those of the Company and that the Representatives have no obligation to disclose such interests and transactions to the
Company by virtue of any fiduciary, advisory or agency relationship; and
(d) it
waives, to the fullest extent permitted by law, any claims it may have against the Representatives for breach of fiduciary duty or alleged
breach of fiduciary duty and agrees that the Representatives shall have no liability (whether direct or indirect) to the Company in respect
of such a fiduciary duty claim or to any person asserting a fiduciary duty claim on behalf of or in right of the Company, including stockholders,
employees or creditors of the Company.
31
12. Successors;
Persons Entitled to Benefit of Agreement. This Agreement shall inure to the benefit of and be binding upon the several Underwriters,
the Company and their respective successors and assigns. Nothing expressed or mentioned in this Agreement is intended or shall be construed
to give any person, other than the persons mentioned in the preceding sentence, any legal or equitable right, remedy or claim under or
in respect of this Agreement, or any provisions herein contained, this Agreement and all conditions and provisions hereof being intended
to be and being for the sole and exclusive benefit of such persons and for the benefit of no other person; except that the representations,
warranties, covenants, agreements and indemnities of the Company contained in this Agreement shall also be for the benefit of the Underwriter
Indemnified Parties, and the indemnities of the several Underwriters shall be for the benefit of the Company Indemnified Parties. It is
understood that each Underwriter’s responsibility to the Company is solely contractual in nature and the Underwriters do not owe
the Company, or any other party, any fiduciary duty as a result of this Agreement. No purchaser of any of the Securities from any Underwriter
shall be deemed to be a successor or assign by reason merely of such purchase.
13. Survival
of Indemnities, Representations, Warranties, etc. The respective indemnities, covenants, agreements, representations,
warranties and other statements of the Company and the several Underwriters, as set forth in this Agreement or made by them respectively,
pursuant to this Agreement, shall remain in full force and effect, regardless of any investigation made by or on behalf of any Underwriter,
the Company or any person controlling any of them and shall survive delivery of and payment for the Securities. Notwithstanding any termination
of this Agreement, including without limitation any termination pursuant to Section 8 or Section 10, the indemnities, covenants,
agreements, representations, warranties and other statements forth in Sections 2, 5, 7 and 9 and Sections 11 through 21, inclusive, of
this Agreement shall not terminate and shall remain in full force and effect at all times.
14. Recognition
of the U.S. Special Resolution Regimes.
(a) In
the event that any Underwriter that is a Covered Entity becomes subject to a proceeding under a U.S. Special Resolution Regime, the transfer
from such Underwriter of this Agreement, and any interest and obligation in or under this Agreement, will be effective to the same extent
as the transfer would be effective under the U.S. Special Resolution Regime if this Agreement, and any such interest and obligation, were
governed by the laws of the United States or a state of the United States.
(b) In
the event that any Underwriter that is a Covered Entity or a BHC Act Affiliate of such Underwriter becomes subject to a proceeding under
a U.S. Special Resolution Regime, Default Rights under this Agreement that may be exercised against such Underwriter are permitted to
be exercised to no greater extent than such Default Rights could be exercised under the U.S. Special Resolution Regime if this Agreement
were governed by the laws of the United States or a state of the United States.
15. Notices.
All statements, requests, notices and agreements hereunder shall be in writing, and:
(a) if
to the Underwriters, shall be delivered or sent by mail, telex, facsimile transmission or email to TD Securities (USA) LLC, 1 Vanderbilt
Avenue, New York, New York 10017, Attention: Head of Equity Capital Markets, with a copy to CIBLegal@tdsecurities.com; and Lake Street
Capital Markets, LLC, 121 South 8th Street, Suite 1000, Minneapolis, Minnesota 55402, Attention: Head of Investment Banking;
(b) if
to the Company, shall be delivered or sent by mail, telex, facsimile transmission or email to Rapid Micro Biosystems, Inc., 1001
Pawtucket Boulevard West, Suite 280, Lowell, MA 01854, Attention: Chief Financial Officer, email: ***, with
a copy to Goodwin Procter LLP, 100 Northern Avenue, Boston, MA 02210, Attention: John Egan and Katie Hand, email: jegan@goodwinlaw.com;
khand@goodwinlaw.com.
provided, however, that any notice to an
Underwriter pursuant to Section 7 shall be delivered or sent by mail, or facsimile transmission to such Underwriter at its address
set forth in its acceptance telex to the Representatives, which address will be supplied to any other party hereto by the Representatives
upon request. Any such statements, requests, notices or agreements shall take effect at the time of receipt thereof.
32
16. Definition
of Certain Terms. For purposes of this Agreement, (a) “affiliate” has the meaning set forth
in Rule 405 under the Securities Act, (b) “business day” means any day on which the Exchange is open
for trading, (c) “subsidiary” has the meaning set forth in Rule 405 of the Rules and Regulations,
(d) “BHC Act Affiliate” has the meaning assigned to the term “affiliate” in, and shall be interpreted
in accordance with, 12 U.S.C. § 1841(k), (e) “Covered Entity” means any of the following: (i) a
“covered entity” as that term is defined in, and interpreted in accordance with, 12 C.F.R. § 252.82(b); (ii) a
“covered bank” as that term is defined in, and interpreted in accordance with, 12 C.F.R. § 47.3(b); or (iii) a
“covered FSI” as that term is defined in, and interpreted in accordance with, 12 C.F.R. § 382.2(b), (f) “Default
Right” has the meaning assigned to that term in, and shall be interpreted in accordance with, 12 C.F.R. §§ 252.81,
47.2 or 382.1, as applicable, and (g) “U.S. Special Resolution Regime” means each of (i) the Federal
Deposit Insurance Act and the regulations promulgated thereunder and (ii) Title II of the Dodd-Frank Wall Street Reform and Consumer
Protection Act and the regulations promulgated thereunder.
17. Governing
Law, Jurisdiction, Waiver of Jury Trial. This Agreement shall be governed by and construed in accordance with the laws of the
State of New York, including without limitation Section 5-1401 of the New York General Obligations. The Company irrevocably (a) submits
to the exclusive jurisdiction of the Federal and state courts in the Borough of Manhattan in The City of New York for the purpose of any
suit, action or other proceeding arising out of this Agreement or the transactions contemplated by this Agreement, the Registration Statement
and the Prospectus, (b) agrees that all claims in respect of any such suit, action or proceeding may be heard and determined by any
such court, (c) waives to the fullest extent permitted by applicable law, any immunity from the jurisdiction of any such court or
from any legal process, (d) agrees not to commence any such suit, action or proceeding other than in such courts, and (e) waives,
to the fullest extent permitted by applicable law, any claim that any such suit, action or proceeding is brought in an inconvenient forum.
Each of the parties to this Agreement hereby waives any right to trial by jury in any suit or proceeding arising out of or relating
to this Agreement.
18. Underwriters’
Information. The parties hereto acknowledge and agree that, for all purposes of this Agreement, the Underwriters’
Information consists solely of the following information in the Prospectus: the statements concerning the Underwriters contained in the
second sentence of the ninth paragraph, the first sentence in the twelfth paragraph and the first sentence of the fourteenth paragraph
under the heading “Underwriting.”
19. Authority
of the Representatives. In connection with this Agreement, the Representatives will act for and on behalf of the several Underwriters,
and any action taken under this Agreement by the Representatives, will be binding on all the Underwriters.
20. Partial
Unenforceability. The invalidity or unenforceability of any section, paragraph, clause or provision of this Agreement shall
not affect the validity or enforceability of any other section, paragraph, clause or provision hereof. If any section, paragraph, clause
or provision of this Agreement is for any reason determined to be invalid or unenforceable, there shall be deemed to be made such minor
changes (and only such minor changes) as are necessary to make it valid and enforceable.
21. General.
This Agreement constitutes the entire agreement of the parties to this Agreement and supersedes all prior written or oral and all contemporaneous
oral agreements, understandings and negotiations with respect to the subject matter hereof. In this Agreement, the masculine, feminine
and neuter genders and the singular and the plural include one another. The section headings in this Agreement are for the convenience
of the parties only and will not affect the construction or interpretation of this Agreement. This Agreement may be amended or modified,
and the observance of any term of this Agreement may be waived, only by a writing signed by the Company and the Representatives.
22. Counterparts.
This Agreement may be signed in any number of counterparts, each of which shall be an original, with the same effect as if the signatures
thereto and hereto were upon the same instrument. This Agreement may be delivered via facsimile, electronic mail (including pdf or any
electronic signature complying with the U.S. federal ESIGN Act of 2000, e.g., www.docusign.com or www.echosign.com) or other transmission
method and any counterpart so delivered shall be deemed to have been duly and validly delivered and be valid and effective for all purposes.
33
If the foregoing is in accordance
with your understanding please indicate your acceptance of this Agreement by signing in the space provided for that purpose below.
Very truly yours,
RAPID MICRO BIOSYSTEMS, INC.
By:
/s/ Sean Wirtjes
Name: Sean Wirtjes
Title: Chief Financial Officer
Accepted as of
the date first above written:
TD Securities
(USA) LLC
Lake
Street Capital Markets, LLC
Acting on their own behalf
and as Representatives of several
Underwriters listed on Schedule A to this Agreement.
By:
TD SECURITIES (USA) LLC
By:
/s/ Peter Callas
Name:
Peter Callas
Title:
Managing Director
By:
Lake
Street Capital Markets, Llc
By:
/s/ Michael Townley
Name:
Michael Townley
Title:
Head of Investment Banking
34
SCHEDULE A
Name
Number of Shares
of Firm Stock to
be Purchased
Number of Pre-Funded
Warrants to be
Purchased
Number of
Accompanying Series
A Common Warrants
to be Purchased
Number of
Accompanying
Series B Common
Warrants to be
Purchased
TD Securities (USA) LLC
2,506,700
1,024,100
3,530,800
3,530,800
Lake Street Capital Markets, LLC
1,074,300
438,900
1,513,200
1,513,200
Total
3,581,000
1,463,000
5,044,000
5,044,000
35
SCHEDULE B
General Use Free Writing Prospectuses
None.
SCHEDULE C
Pricing Information
Firm Stock to be Sold: 3,581,000 shares
Pre-Funded Warrants to be Sold: 1,463,000
Series A Common Warrants to be Sold: 5,044,000
Series B Common Warrants to be Sold: 5,044,000
Exercise Price of Series A Common Warrants:
$1.955 per share
Exercise Price of Series B Common Warrants:
$2.340 per share
Offering Price per Share of Common Stock and accompanying
Series A Common Warrant and Series B Common Warrant: $1.955
Offering Price per Pre-Funded Warrant and accompanying
Series A Common Warrant and Series B Common Warrant: $1.945
Underwriting Discounts and Commissions: 6.00%
Estimated Net Proceeds to the Company (after underwriting discounts
and commissions, but before transaction expenses): $9,254,729
The number of Shares offered in the Concurrent Offering: 71,607
2
SCHEDULE D
Directors & Officers
1. Robert
Spignesi
2. Sean
Wirtjes
3. Dafni
Bika
4. Richard
Kollender
5. Melinda
Litherland
6. Inese
Lowenstein
7. Kirk
D. Malloy
8. Natale
Ricciardi
Exhibit I
Form of Lock-Up Agreement
May [●], 2026
TD Securities
(USA) LLC
Lake Street
Capital Markets, LLC
As Representatives
of the several Underwriters
c/o TD Securities (USA) LLC
1 Vanderbilt Avenue
New York, New York 10017
c/o Lake Street Capital Markets, LLC
121 South 8th Street, Suite 1000
Minneapolis, Minnesota 55402
Re: Rapid Micro Biosystems, Inc. –
Registration Statement on Form S-3 for Shares of Class A Common Stock
Dear Sirs and Madams:
This letter agreement (“Agreement”)
is being delivered to you in connection with the proposed Underwriting Agreement (the “Underwriting Agreement”) between Rapid
Micro Biosystems, Inc., a Delaware corporation (the “Company”), and TD Securities (USA) LLC (“TD Cowen”)
and Lake Street Capital Markets, LLC (“Lake Street”), as representatives (the “Representatives”) of a group of
underwriters (collectively, the “Underwriters”), to be named therein, and the other parties thereto (if any), relating to
the proposed public offering of shares of the Class A common stock, par value $0.01 per share (the “Common Stock”) of
the Company (the “Offering”).
In order to induce the Underwriters to enter into
the Underwriting Agreement, and in light of the benefits that the Offering will confer upon the undersigned in his, her or its capacity
as a securityholder and/or an officer or director of the Company, and for good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, the undersigned agrees with each Underwriter that, during the period beginning on the date hereof through
and including the date that is the 60th day after the date of the Underwriting Agreement (the “Lock-Up Period”),
the undersigned will not, and will not cause or direct any of its affiliates to, without the prior written consent of TD Cowen and Lake
Street, directly or indirectly, (i) offer, sell, assign, transfer, pledge, contract to sell, lend or otherwise dispose of, or publicly
announce the intention to otherwise dispose of, any shares of Common Stock (including, without limitation, Common Stock which may be deemed
to be beneficially owned by the undersigned in accordance with the rules and regulations promulgated under the Securities Exchange
Act of 1934, as amended (the “Exchange Act”) as the same may be amended or supplemented from time to time (such shares, the
“Beneficially Owned Shares”)) or securities convertible into or exercisable or exchangeable for Common Stock, (ii) enter
into, or publicly announce the intention to enter into, any swap, hedge or similar agreement or arrangement (including, without limitation,
the purchase or sale of, or entry into, any put or call option, or combination thereof, forward, swap or any other derivative transaction
or instrument, however described or defined) that transfers, is designed to transfer or reasonably could be expected to transfer (whether
by the undersigned or someone other than the undersigned) in whole or in part, directly or indirectly, the economic risk of ownership
of the Beneficially Owned Shares or securities convertible into or exercisable or exchangeable for Common Stock, whether now owned or
hereafter acquired by the undersigned or with respect to which the undersigned has or hereafter acquires the power of disposition (the
“Prohibited Activity”), or (iii) engage in, or publicly announce the intention to engage in, any short selling of the
Common Stock or securities convertible into or exercisable or exchangeable for Common Stock. The undersigned represents and warrants that
the undersigned is not, and has not caused or directed any of its affiliates to be or become, currently a party to any agreement or arrangement
that is designed to or which reasonably could be expected to lead to or result in any Prohibited Activity during the Lock-Up Period.
2
If the undersigned is not a natural person, the
undersigned represents and warrants that no single natural person, entity or “group” (within the meaning of Section 13(d)(3) of
the Exchange Act), other than a natural person, entity or “group” (as described above) that has executed an Agreement in substantially
the same form as this Agreement, beneficially owns, directly or indirectly, 50% or more of the common equity interests, or 50% or more
of the voting power, in the undersigned.
The restrictions set forth in the immediately
preceding paragraphs shall not apply to:
(1) if
the undersigned is a natural person, any transfers made by the undersigned (a) as a bona fide gift to any member of the immediate
family (as defined below) of the undersigned or to a trust the beneficiaries of which are exclusively the undersigned or members of the
undersigned’s immediate family, (b) by will, other testamentary document or intestate succession upon the death of the undersigned,
(c) as a bona fide gift to a charity or educational institution, or (d) transfers that occur solely by operation of law pursuant
to a qualified domestic order or in connection with a divorce settlement,
(2) if
the undersigned is a corporation, partnership, limited liability company or other business entity, any transfers or distributions to any
stockholder, partner or member of, or beneficial owner of a similar equity interest in, the undersigned, as the case may be, if, in any
such case, such transfer is not for value,
(3) if
the undersigned is a corporation, partnership, limited liability company or other business entity, any transfer made by the undersigned
(a) in connection with the sale or other bona fide transfer in a single transaction of all or substantially all of the undersigned’s
capital stock, partnership interests, membership interests or other similar equity interests, as the case may be, or all or substantially
all of the undersigned’s assets, in any such case not undertaken for the purpose of avoiding the restrictions imposed by this Agreement
or (b) to another corporation, partnership, limited liability company or other business entity so long as the transferee is an affiliate
(as defined below) of the undersigned and such transfer is not for value,
(4) transactions
relating to Common Stock or other securities convertible into or exercisable or exchangeable for Common Stock acquired in open market
transactions after completion of the Offering, provided that no such transaction is required to be, or is, publicly announced (whether
on Form 4, Form 5 or otherwise) during the Lock-Up Period,
(5) the
entry, by the undersigned, at any time on or after the date of the Underwriting Agreement, of any trading plan providing for the sale
of Common Stock by the undersigned, which trading plan meets the requirements of Rule 10b5-1(c) under the Exchange Act, provided,
however, that such plan does not provide for, or permit, the sale of any Common Stock during the Lock-up Period and, except as required
by applicable securities laws, no public announcement or filing is voluntarily made or required regarding such plan during the Lock-Up
Period,
3
(6) any
transfers or dispositions made by the undersigned to satisfy tax withholding obligations pursuant to the Company’s equity incentive
plans or arrangements disclosed in the Prospectus (as defined in the Underwriting Agreement); and
(7) the transfer of shares of Common
Stock under a trading plan pursuant to Rule 10b5-1 under the Exchange Act (a “Trading Plan”) that is existing on the
date hereof which has been provided to TD Cowen and Lake Street or its legal counsel; provided, that, to the extent a public announcement
or filing under the Exchange Act, if any, is required of or voluntarily made by or on behalf of the undersigned or the Company regarding
such transfer, such announcement or filing shall include a statement that such transfer is in accordance with an established Trading Plan.
provided, however, that in the case of any transfer
described in clause (1), (2) or (3) above, it shall be a condition to the transfer that (A) the transferee executes
and delivers to TD Cowen and Lake Street, acting on behalf of the Underwriters, not later than one business day prior to such transfer,
a written agreement, in substantially the form of this Agreement (it being understood that any references to “immediate family”
in the agreement executed by such transferee shall expressly refer only to the immediate family of the undersigned and not to the immediate
family of the transferee) and otherwise satisfactory in form and substance to TD Cowen and Lake Street, and (B) in the case of any
transfer described in clause (1), (2), (3) or (6) above, no public announcement or filing is voluntarily made regarding such
transfer during the Lock-Up Period and if the undersigned is required to file a report under Section 16(a) of the Exchange Act,
reporting a reduction in beneficial ownership of shares of Common Stock or Beneficially Owned Shares or any securities convertible into
or exercisable or exchangeable for Common Stock or Beneficially Owned Shares during the Lock-Up Period, the undersigned shall include
a statement in such report to the effect that, (A) in the case of any transfer pursuant to clause (1) above, such transfer
is being made as a gift or by will or intestate succession, (B) in the case of any transfer pursuant to clause (2) above,
such transfer is being made to a stockholder, partner or member of, or beneficial owner of a similar equity interest in, the undersigned
and is not a transfer for value, (C) in the case of any transfer pursuant to clause (3) above, such transfer is being made either
(a) in connection with the sale or other bona fide transfer in a single transaction of all or substantially all of the undersigned’s
capital stock, partnership interests, membership interests or other similar equity interests, as the case may be, or all or substantially
all of the undersigned’s assets or (b) to another corporation, partnership, limited liability company or other business entity
that is an affiliate of the undersigned and such transfer is not for value, and (D) in the case of a transfer pursuant to clause
(6) above, such transfer is being made to satisfy tax withholding obligations. For purposes of this paragraph, “immediate family”
shall mean a spouse, child, grandchild or other lineal descendant (including by adoption), father, mother, brother or sister of the undersigned;
and “affiliate” shall have the meaning set forth in Rule 405 under the Securities Act of 1933 (the “Securities
Act”).
For avoidance of doubt, nothing in this Agreement
prohibits the undersigned from exercising any options or warrants to purchase Common Stock (which exercises may be effected on a cashless
basis to the extent the instruments representing such options or warrants permit exercises on a cashless basis), it being understood that
any Common Stock issued upon such exercises will be subject to the restrictions of this Agreement and provided, however, that no public
announcement or filing is voluntarily made regarding such exercise during the Lock-Up Period and provided that if the undersigned is required
to file a report under Section 16(a) of the Exchange Act reporting a reduction in beneficial ownership of such options or warrants
during the Lock-Up Period, the undersigned shall include a statement in such report to the effect that the disposition relates to the
exercise of an option or warrant, as applicable, and that the shares of Common Stock received upon exercise are subject to the restrictions
of this Agreement.
In order to enable this covenant to be enforced,
the undersigned hereby consents to the placing of legends or stop transfer instructions with the Company’s transfer agent with respect
to any Common Stock or securities convertible into or exercisable or exchangeable for Common Stock.
4
The undersigned further agrees that it will not,
during the Lock-Up Period, make any demand or request for or exercise any right with respect to the registration under the Securities
Act, of any shares of Common Stock or other Beneficially Owned Shares or any securities convertible into or exercisable or exchangeable
for Common Stock or other Beneficially Owned Shares.
The undersigned hereby represents and warrants
that the undersigned has full power and authority to enter into this Agreement and that this Agreement has been duly authorized (if the
undersigned is not a natural person), executed and delivered by the undersigned and is a valid and binding agreement of the undersigned.
This Agreement and all authority herein conferred are irrevocable and shall survive the death or incapacity of the undersigned (if a natural
person) and shall be binding upon the heirs, personal representatives, successors and assigns of the undersigned.
The undersigned acknowledges and agrees that the
Underwriters have not provided any recommendation or investment advice nor have the Underwriters solicited any action from the undersigned
with respect to the Offering and the undersigned has consulted their own legal, accounting, financial, regulatory and tax advisors to
the extent deemed appropriate. The undersigned further acknowledges and agrees that, although the Representatives may be required or choose
to provide certain Regulation Best Interest and Form CRS disclosures to you in connection with the Offering, the Representatives
and the other Underwriters are not making a recommendation to you to enter into this Agreement and nothing set forth in such disclosures
is intended to suggest that the Representatives or any Underwriter is making such a recommendation.
This Agreement shall be governed by and construed
in accordance with the internal laws of the State of New York applicable to agreements made and to be performed in such state.
This Agreement may be delivered via facsimile,
electronic mail (including pdf or any electronic signature complying with the U.S. federal ESIGN Act of 2000, e.g., www.docusign.com or
www.echosign.com) or other transmission method and any copy so delivered shall be deemed to have been duly and validly delivered and be
valid and effective for all purposes.
If (i) the Company notifies TD Cowen and
Lake Street in writing that it does not intend to proceed with the Offering, (ii) TD Cowen and Lake Street notify the Company in
writing that they do not intend to proceed with the Offering, (iii) the Underwriting Agreement is not executed by May 29, 2026,
or (iv) the Underwriting Agreement (other than the provisions thereof which survive termination) shall terminate or be terminated
for any reason prior to payment for and delivery of any Common Stock to be sold thereunder, then this Agreement shall immediately be terminated
and the undersigned shall automatically be released from all of his, her or its obligations under this Agreement. The undersigned acknowledges
and agrees that whether or not any public offering of Common Stock actually occurs depends on a number of factors, including market conditions.
[Signature page follows]
5
Very truly yours,
(Name of Stockholder - Please Print)
(Signature)
(Name of Signatory if Stockholder is an entity
- Please Print)
(Title of Signatory if Stockholder is an entity
- Please Print)
Address:
6
Exhibit II
Form of CFO Certificate
[Attached.]
EX-4.1 — EXHIBIT 4.1
EX-4.1
Filename: tm2614922d1_ex4-1.htm · Sequence: 3
Exhibit 4.1
RAPID MICRO BIOSYSTEMS, INC.
WARRANT TO PURCHASE COMMON STOCK
Number of Shares: [_________] (subject to adjustment)
Warrant No. PFW-[ ]
Original Issue Date: May [ ], 2026
Rapid Micro Biosystems, Inc., a Delaware
corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, [___________] or its registered assigns (the “Holder”) is entitled, subject to the
terms set forth below, to purchase from the Company up to a total of [______] shares of Class A common stock, $0.01 par value per
share (the “Common Stock”), of the Company (each such share, a “Warrant Share” and all such shares,
the “Warrant Shares”) at an exercise price per share equal to $0.01 per share (as adjusted from time to time as provided
in Section 9 herein, the “Exercise Price”) upon surrender of this Warrant to Purchase Common Stock (including
any Warrants to Purchase Common Stock issued in exchange, transfer or replacement hereof, the “Warrant”) at any time
and from time to time on or after the date hereof (the “Original Issue Date”), subject to the following terms and conditions:
1. Definitions. For purposes of this Warrant,
the following terms shall have the following meanings: (a) “Affiliate” means any Person directly or indirectly
controlled by, controlling or under common control with, a Holder, as such terms are used in and construed under Rule 405 under the
Securities Act, but only for so long as such control shall continue.
(b) “Commission” means
the United States Securities and Exchange Commission.
(c) “Closing Sale Price”
means, for any security as of any date, the last trade price for such security on the Principal Trading Market for such security, as reported
by Bloomberg L.P., or, if such Principal Trading Market begins to operate on an extended hours basis and does not designate the last trade
price, then the last trade price of such security prior to 4:00 P.M., New York City time, as reported by Bloomberg L.P., or if the security
is not listed for trading on a national securities exchange or other trading market on the relevant date, the last quoted bid price for
the security in the over-the-counter market on the relevant date as reported by OTC Markets Group Inc. (or a similar organization or agency
succeeding to its functions of reporting prices). If the Closing Sale Price cannot be calculated for a security on a particular date on
any of the foregoing bases, the Closing Sale Price of such security on such date shall be the fair market value as mutually determined
by the Company and the Holder. If the Company and the Holder are unable to agree upon the fair market value of such security, then the
Board of Directors of the Company shall use its good faith judgment to determine the fair market value. The Board of Directors’
determination shall be binding upon all parties absent demonstrable error. All such determinations shall be appropriately adjusted for
any stock dividend, stock split, stock combination or other similar transaction during the applicable calculation period.
(d) “Marketable Securities”
means securities meeting all of the following requirements: (i) the issuer thereof is then subject to the reporting requirements
of Section 13 or Section 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
and is then current in its filing of all required reports and other information under the Securities Act and the Exchange Act; (ii) the
class and series of shares or other security of the issuer that would be received by Holder in connection with the Fundamental Transaction
(as defined below) were Holder to exercise this Warrant on or prior to the closing thereof is then traded or quoted on a nationally recognized
securities exchange, inter-dealer quotation system or over-the-counter market, and (iii) following the closing of such Fundamental
Transaction, the Holder would not be restricted from publicly re-selling all of the issuer’s shares and/or other securities that
would be received by the Holder in such Fundamental Transaction were the Holder to exercise or convert this Warrant in full on or prior
to the closing of such Fundamental Transaction.
(e) “Principal Trading Market”
means the national securities exchange or other trading market on which the Common Stock is primarily listed on and quoted for trading,
which, as of the Original Issue Date, shall be the Nasdaq Capital Market.
(f) “Registration Statement”
means the Company’s Registration Statement on Form S-3 (File No 333- 276081), as filed with the Commission on December 15,
2023 and declared effective on December 26, 2023.
(g) “Securities Act” means
the Securities Act of 1933, as amended.
(h) “Standard Settlement Period”
means the standard settlement period, expressed in a number of Trading Days, for the Company’s primary trading market or quotation
system with respect to the Common Stock that is in effect on the date of delivery of an applicable Exercise Notice, which as of the Original
Issue Date is “T+1”.
(h) “Trading Day” means
any weekday on which the Principal Trading Market is open for trading. If the Common Stock is not listed or admitted for trading, “Trading
Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the United States or any day on
which banking institutions in New York City are authorized or required by law or other governmental action to close.
(i) “Transfer Agent” means
Computershare Trust Company, N.A., the Company’s transfer agent and registrar for the Common Stock, and any successor appointed
in such capacity.
2. Issuance of Securities; Registration of
Warrants. The Warrant, as initially issued by the Company, is offered and sold pursuant to the Registration Statement. As of the Original
Issue Date, the Warrant Shares are issuable under the Registration Statement. Accordingly, the Warrant and, assuming issuance pursuant
to the Registration Statement or an exchange meeting the requirements of Section 3(a)(9) of the Exchange Act as in effect on
the Original Issue Date, the Warrant Shares, are not “restricted securities” under Rule 144 promulgated under the Securities
Act. The Company shall register ownership of this Warrant, upon records to be maintained by the Company for that purpose (the “Warrant
Register”), in the name of the record Holder (which shall include the initial Holder or, as the case may be, any assignee to
which this Warrant is assigned hereunder) from time to time. The Company may deem and treat the registered Holder of this Warrant as the
absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder, and for all other purposes, absent actual
notice to the contrary.
3. Registration of Transfers. Subject to
compliance with all applicable securities laws, the Company shall, or will cause its Transfer Agent to, register the transfer of all or
any portion of this Warrant in the Warrant Register, upon surrender of this Warrant, and payment for all applicable transfer taxes (if
any). Upon any such registration or transfer, a new warrant to purchase Common Stock in substantially the form of this Warrant (any such
new warrant, a “New Warrant”) evidencing the portion of this Warrant so transferred shall be issued to the transferee,
and a New Warrant evidencing the remaining portion of this Warrant not so transferred, if any, shall be issued to the transferring Holder.
The acceptance of the New Warrant by the transferee thereof shall be deemed the acceptance by such transferee of all of the rights and
obligations in respect of the New Warrant that the Holder has in respect of this Warrant. The Company shall, or will cause its Transfer
Agent to, prepare, issue and deliver at the Company’s own expense any New Warrant under this Section 3. Until due presentment
for registration of transfer, the Company may treat the registered Holder hereof as the owner and holder for all purposes, and the Company
shall not be affected by any notice to the contrary.
4. Exercise and Duration of Warrants.
(a) All or any part of this Warrant shall
be exercisable by the registered Holder in the manner set forth in Section 10 at any time and from time to time on or after the Original
Issue Date, and such rights shall not expire.
(b) The Holder may exercise this
Warrant by delivering to the Company an exercise notice, in the form attached as Schedule 1 hereto (the “Exercise
Notice”), completed and duly signed. The date on which such exercise notice is delivered to the Company (as determined in
accordance with the notice provisions hereof) is an “Exercise Date.” The Holder shall not be required to deliver
the original Warrant in order to effect an exercise hereunder. Execution and delivery of the Exercise Notice shall have the same
effect as cancellation of the original Warrant and issuance of a New Warrant evidencing the right to purchase the remaining number
of Warrant Shares, if any. The Holder and any assignee, by acceptance of this Warrant, acknowledge and agree that, by reason of
the provisions of this paragraph, following the purchase of a portion of the Warrant Shares hereunder, the number of Warrant Shares
available for purchase hereunder at any given time may be less than the amount stated on the face hereof.
5. Delivery of Warrant Shares.
(a) Upon exercise of this Warrant, the Company
shall, or shall cause the Transfer Agent to, promptly (but in no event later than the number of Trading Days comprising the Standard Settlement
Period following the Exercise Date), upon the request of the Holder, credit such aggregate number of shares of Common Stock to which the
Holder is entitled pursuant to such exercise to the Holder’s or its designee’s balance account with The Depository Trust Company
(“DTC”) through its Deposit Withdrawal Agent Commission system, or if the Transfer Agent is not participating in the
Fast Automated Securities Transfer Program or if the certificates are required to bear a legend regarding restriction on transferability,
issue and dispatch by overnight courier to the address as specified in the Exercise Notice, a certificate, registered in the Company’s
share register in the name of the Holder or its designee, for the number of shares of Common Stock to which the Holder is entitled pursuant
to such exercise. The Holder, or any natural person or legal entity (each, a “Person”) so designated by the Holder
to receive Warrant Shares, shall be deemed to have become the holder of record of such Warrant Shares as of the Exercise Date, irrespective
of the date such Warrant Shares are credited to the Holder’s DTC account or the date of delivery of the certificates evidencing
such Warrant Shares, as the case may be.
(b) If the Company fails to deliver to the
Holder a certificate representing the required number of Warrant Shares in the manner required pursuant to Section 5(a) or
fails to credit the Holder’s DTC account for such number of Warrant Shares to which the Holder is entitled within the Standard Settlement
Period following the Exercise Date, and if after such Standard Settlement Period and prior to the receipt of such Warrant Shares, the
Holder purchases (in an open market transaction or otherwise) shares of Common Stock to deliver in satisfaction of a sale by the Holder
of the Warrant Shares which the Holder anticipated receiving upon such exercise (a “Buy-In”), then the Company shall,
within three (3) Trading Days after the Holder’s request promptly honor its obligation to deliver to the Holder a certificate
or certificates representing such Warrant Shares and pay cash to the Holder in an amount equal to the excess (if any) of Holder’s
total purchase price (including brokerage commissions, if any) for the shares of Common Stock so purchased in the Buy-In less the product
of (A) the number of shares of Common Stock purchased in the Buy-In, times (B) the Closing Sale Price of a share of Common Stock
on the Exercise Date.
(c) To the extent permitted by law and subject
to Section 5(b), the Company’s obligations to issue and deliver Warrant Shares in accordance with and subject to the terms
hereof (including the limitations set forth in Section 11 below) are absolute and unconditional, irrespective of any action or inaction
by the Holder to enforce the same, any waiver or consent with respect to any provision hereof, the recovery of any judgment against any
Person or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation or termination, or any breach or alleged
breach by the Holder or any other Person of any obligation to the Company or any violation or alleged violation of law by the Holder or
any other Person, and irrespective of any other circumstance that might otherwise limit such obligation of the Company to the Holder in
connection with the issuance of Warrant Shares. Subject to Section 5(b), nothing herein shall limit the Holder’s right to pursue
any other remedies available to it hereunder, at law or in equity including, without limitation, a decree of specific performance and/or
injunctive relief with respect to the Company’s failure to timely deliver shares of Common Stock upon exercise of the Warrant as
required pursuant to the terms hereof.
6. Charges, Taxes and Expenses. Issuance
and delivery of shares of Common Stock upon exercise of this Warrant shall be made without charge to the Holder for any issue or transfer
tax, transfer agent fee or other incidental tax or expense (excluding any applicable stamp duties) in respect of the issuance of such
shares, all of which taxes and expenses shall be paid by the Company; provided, however, that the Company shall not be required
to pay any tax that may be payable in respect of any transfer involved in the registration of any Warrant Shares or the Warrants in a
name other than that of the Holder or an Affiliate thereof. The Holder shall be responsible for all other tax liability that may arise
as a result of holding or transferring this Warrant or receiving Warrant Shares upon exercise hereof.
7. Replacement of Warrant. If this Warrant
is mutilated, lost, stolen or destroyed, the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation
hereof, or in lieu of and substitution for this Warrant, a New Warrant, but only upon receipt of evidence reasonably satisfactory to the
Company of such loss, theft or destruction (in such case) and, in each case, a customary and reasonable indemnity and surety bond, if
requested by the Company. Applicants for a New Warrant under such circumstances shall also comply with such other reasonable regulations
and procedures and pay such other reasonable third-party costs as the Company may prescribe. If a New Warrant is requested as a result
of a mutilation of this Warrant, then the Holder shall deliver such mutilated Warrant to the Company as a condition precedent to the Company’s
obligation to issue the New Warrant.
8. Reservation of Warrant Shares. The Company
covenants that it will, at all times while this Warrant is outstanding, reserve and keep available out of the aggregate of its authorized
but unissued and otherwise unreserved Common Stock, solely for the purpose of enabling it to issue Warrant Shares upon exercise of this
Warrant as herein provided, the number of Warrant Shares that are initially issuable and deliverable upon the exercise of this entire
Warrant, free from preemptive rights or any other contingent purchase rights of persons other than the Holder (taking into account the
adjustments and restrictions of Section 9). The Company covenants that all Warrant Shares so issuable and deliverable shall, upon
issuance and the payment of the applicable Exercise Price in accordance with the terms hereof, be duly and validly authorized, issued
and fully paid and non-assessable. The Company will take all such action as may be reasonably necessary to assure that such shares of
Common Stock may be issued as provided herein without violation of any applicable law or regulation, or of any requirements of any securities
exchange or automated quotation system upon which the Common Stock may be listed. The Company further covenants that it will not, without
the prior written consent of the Holder, take any actions to increase the par value of the Common Stock at any time while this Warrant
is outstanding.
9. Certain Adjustments. The Exercise Price
and number of Warrant Shares issuable upon exercise of this Warrant (the “Number of Warrant Shares”) are subject to
adjustment from time to time as set forth in this Section 9.
(a) Stock Dividends and Splits. If
the Company, at any time while this Warrant is outstanding, (i) pays a stock dividend on its Common Stock that is payable in shares
of Common Stock, (ii) subdivides its outstanding shares of Common Stock into a larger number of shares of Common Stock, (iii) combines
its outstanding shares of Common Stock into a smaller number of shares of Common Stock or (iv) issues by reclassification of shares
of capital stock any additional shares of Common Stock of the Company, then in each such case the Number of Warrant Shares shall be multiplied
by a fraction, the numerator of which shall be the number of shares of Common Stock outstanding immediately after such event and the denominator
of which shall be the number of shares of Common Stock outstanding immediately before such event. Any adjustment made pursuant to clause
(i) of this paragraph shall become effective immediately after the record date for the determination of stockholders entitled to
receive such dividend or distribution, provided, however, that if such record date shall have been fixed and such dividend is not fully
paid on the date fixed therefor, the Number of Warrant Shares shall be recomputed accordingly as of the close of business on such record
date and thereafter the Number of Warrant Shares shall be adjusted pursuant to this paragraph as of the time of actual payment of such
dividends. Any adjustment pursuant to clause (ii), (iii) or (iv) of this paragraph shall become effective immediately after
the effective date of such subdivision, combination or issuance.
(b) Pro Rata Distributions. If the
Company, at any time while this Warrant is outstanding, distributes to all holders of Common Stock for no consideration (i) evidences
of its indebtedness, (ii) any security (other than a distribution of Common Stock covered by the preceding paragraph), (iii) rights
or warrants to subscribe for or purchase any security (including Common Stock), or (iv) cash or any other asset (in each case, a
“Distribution”), other than a reclassification as to which Section 9(c) applies, then in each such case,
the Holder shall be entitled to participate in such Distribution to the same extent that the Holder would have participated therein if
the Holder had held the number of shares of Common Stock acquirable upon complete exercise of this Warrant (without regard to any limitations
on exercise hereof, including without limitation, the ownership limitation set forth in Section 11(a) hereof) immediately before
the date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders of
Common Stock are to be determined for the participation in such Distribution; provided, however, to the extent that the
Holder’s right to participate in any such Distribution would result in the Holder exceeding the ownership limitation set forth in
Section 11(a) hereof, then the Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial
ownership of any Common Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance
for the benefit of the Holder until such time, if ever, as the delivery to such Holder of such portion would not result in the Holder
exceeding the ownership limitation set forth in Section 11(a) hereof.
(c) Fundamental Transactions. If,
at any time while this Warrant is outstanding (i) the Company effects any merger or consolidation of the Company with or into another
Person, in which the Company is not the surviving entity, (ii) the Company effects any sale to another Person of all or substantially
all of its assets in one transaction or a series of related transactions, (iii) pursuant to any tender offer or exchange offer (whether
by the Company or another Person), holders of capital stock tender shares representing more than 50% of the voting power of the capital
stock of the Company and the Company or such other Person, as applicable, accepts such tender for payment, (iv) the Company consummates
a stock purchase agreement or other business combination (including, without limitation, a reorganization, recapitalization, spin-off
or scheme of arrangement) with another Person whereby such other Person acquires more than the 50% of the voting power of the capital
stock of the Company (except for any such transaction in which the stockholders of the Company immediately prior to such transaction maintain,
in substantially the same proportions, the voting power of such Person immediately after the transaction) or (v) the Company effects
any reclassification of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively converted
into or exchanged for other securities, cash or property (other than as a result of a subdivision or combination of shares of Common Stock
covered by Section 9(a) above) (in any such case, a “Fundamental Transaction”), then following such Fundamental
Transaction the Holder shall have the right to receive, upon exercise of this Warrant, the same amount and kind of securities, cash or
property as it would have been entitled to receive upon the occurrence of such Fundamental Transaction if it had been, immediately prior
to such Fundamental Transaction, the holder of the Number of Warrant Shares without regard to any limitations on exercise contained herein
(in the case of clause (iii) above, assuming it had tendered, and the offeror had accepted, such Warrant Shares) (the “Alternate
Consideration”). The Company shall not effect any Fundamental Transaction in which the Company is not the surviving entity or
the Alternate Consideration includes securities of another Person unless (i) the Alternate Consideration is solely cash and the Company
provides for the simultaneous “cashless exercise” of this Warrant pursuant to Section 10 below or (ii) prior to
or simultaneously with the consummation thereof, any successor to the Company, surviving entity or other Person (including any purchaser
of assets of the Company) shall assume the obligation to deliver to the Holder such Alternate Consideration as, in accordance with the
foregoing provisions, the Holder may be entitled to receive, and the other obligations under this Warrant. The provisions of this paragraph
(c) shall similarly apply to subsequent transactions analogous of a Fundamental Transaction type. Notwithstanding the foregoing,
in the event of a Fundamental Transaction where the consideration payable to holders of Common Stock consists solely of cash, solely of
Marketable Securities or a combination of cash and Marketable Securities, then this Warrant shall automatically be deemed to be exercised
in full in a “cashless exercise” pursuant to Section 10 below effective immediately prior to and contingent upon the
consummation of such Fundamental Transaction.
(d) Exercise Price. Simultaneously
with any adjustment to the Number of Warrant Shares pursuant to Section 9 the Exercise Price shall be increased or decreased proportionately,
so that after such adjustment the aggregate Exercise Price payable hereunder for the increased or decreased Number of Warrant Shares shall
be the same as the aggregate Exercise Price in effect immediately prior to such adjustment. Notwithstanding the foregoing, in no event
may the Exercise Price be adjusted below the par value of the Common Stock then in effect.
(e) Calculations. All calculations
under this Section 9 shall be made to the nearest one-hundredth of one cent or the nearest whole share, as applicable.
(f) Notice of Adjustments. Upon the
occurrence of each adjustment pursuant to this Section 9, the Company at its expense will, at the written request of the Holder,
promptly compute such adjustment, in good faith, in accordance with the terms of this Warrant and prepare a certificate setting forth
such adjustment, including a statement of the adjusted Exercise Price and adjusted number or type of Warrant Shares or other securities
issuable upon exercise of this Warrant (as applicable), describing the transactions giving rise to such adjustments and showing in detail
the facts upon which such adjustment is based. Upon written request, the Company will promptly deliver a copy of each such certificate
to the Holder and to the Company’s transfer agent.
(g) Notice of Corporate Events. If,
while this Warrant is outstanding, the Company (i) declares a dividend or any other distribution of cash, securities or other property
in respect of its Common Stock, including, without limitation, any granting of rights or warrants to subscribe for or purchase any capital
stock of the Company or any subsidiary, (ii) authorizes or approves, enters into any agreement contemplating or solicits stockholder
approval for any Fundamental Transaction or (iii) authorizes the voluntary dissolution, liquidation or winding up of the affairs
of the Company, then, except if such notice and the contents thereof shall be deemed to constitute material non-public information, the
Company shall deliver to the Holder a notice of such transaction at least ten (10) days prior to the applicable record or effective
date on which a Person would need to hold Common Stock in order to participate in or vote with respect to such transaction; provided,
however, that the failure to deliver such notice or any defect therein shall not affect the validity of the corporate action required
to be described in such notice. In addition, if while this Warrant is outstanding, the Company authorizes or approves, enters into any
agreement contemplating or solicits stockholder approval for any Fundamental Transaction contemplated by Section 9(c), other than
a Fundamental Transaction under clause (iii) of Section 9(c), then, except if such notice and the contents thereof shall be
deemed to constitute material non-public information, the Company shall deliver to the Holder a notice of such Fundamental Transaction
at least ten (10) days prior to the date such Fundamental Transaction is consummated.
10. Cashless Exercise. Notwithstanding
anything contained herein to the contrary, this Warrant may only be exercised through a “cashless exercise.” Upon exercise,
the Company shall issue to the Holder the number of Warrant Shares in an exchange of securities effected pursuant to Section 3(a)(9) of
the Securities Act as determined as follows:
X = Y [(A-B)/A]
where:
“X” equals the number of Warrant Shares to be issued to
the Holder;
“Y” equals the total number of Warrant Shares with respect
to which this Warrant is then being exercised;
“A” equals the Closing Sale Price per share of Common Stock
as of the Trading Day on the date immediately preceding the Exercise Date; and
“B” equals the Exercise Price per Warrant Share then in
effect on the Exercise Date.
For purposes of Rule 144 promulgated under
the Securities Act, it is intended, understood and acknowledged that the Warrant Shares issued in such a “cashless exercise”
transaction shall be deemed to have been acquired by the Holder, and the holding period for the Warrant Shares shall be deemed to have
commenced, on the date this Warrant was originally issued (provided that the Commission continues to take the position that such treatment
is proper at the time of such exercise).
In no event will the exercise of this Warrant be settled in cash.
11. Limitations on Exercise.
(a) Notwithstanding anything to the contrary
contained herein, the Company shall not effect any exercise of this Warrant, and the Holder shall not be entitled to exercise this Warrant
(i) if immediately prior to the exercise, the Holder, its Affiliates and any other Persons whose beneficial ownership of Common Stock
would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act, beneficially own an aggregate
number of shares of Common Stock greater than [4.5] [4.99] [9.99] % (the “Maximum Percentage”) of the total number
of issued and outstanding shares of Common Stock of the Company without taking into account any Warrant Shares, or (ii) to the extent
that immediately following the exercise, the Holder, its Affiliates and any other Persons whose beneficial ownership of Common Stock would
be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act, would beneficially own in excess of
the Maximum Percentage of the number of shares of Common Stock outstanding immediately after giving effect to the issuance of such shares
of Common Stock. Any portion of an exercise that would result in the issuance of shares in excess of the Maximum Percentage shall be treated
as null and void ab initio. For purposes of this Warrant, in determining the number of outstanding shares of Common Stock, the Holder
may rely on the number of outstanding shares of Common Stock as reflected in (x) the Company’s most recent Form 10-Q or
Form 10-K, as the case may be, filed with the Commission prior to the date hereof, (y) a more recent public announcement by
the Company or (z) any other notice by the Company or its transfer agent setting forth the number of shares of Common Stock outstanding.
Upon the written request of the Holder, the Company shall within three (3) Trading Days confirm in writing or by electronic mail
to the Holder the number of shares of Common Stock then outstanding. In any case, the number of outstanding shares of Common Stock shall
be determined after giving effect to the conversion or exercise of securities of the Company, including this Warrant, by the Holder since
the date as of which such number of outstanding shares of Common Stock was reported. By written notice to the Company, the Holder may
from time to time increase or decrease the Maximum Percentage to any other percentage specified not in excess of 19.99% specified in such
notice; provided that any such increase will not be effective until the sixty-first (61st) day after such notice is delivered to the Company.
For purposes of this Section 11(a), the aggregate number of shares of Common Stock or voting securities beneficially owned by the
Holder and its Affiliates and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s
for purposes of Section 13(d) of the Exchange Act shall include the shares of Common Stock issuable upon the exercise of this
Warrant with respect to which such determination is being made, but shall exclude the number of shares of Common Stock which would be
issuable upon (x) exercise of the remaining unexercised and non-cancelled portion of this Warrant by the Holder and (y) exercise
or conversion of the unexercised, non-converted or non-cancelled portion of any other securities of the Company that do not have voting
power (including without limitation any securities of the Company which would entitle the holder thereof to acquire at any time Common
Stock, including without limitation any debt, preferred stock, right, option, warrant or other instrument that is at any time convertible
into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock), is subject to a limitation
on conversion or exercise analogous to the limitation contained herein and is beneficially owned by the Holder or any of its Affiliates
and other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of
the Exchange Act. For purposes of clarity, the Warrant Shares issuable pursuant to the terms of this Warrant in excess of the Maximum
Percentage shall not be deemed to be beneficially owned by the Holder for any purpose including for purposes of Section 13(d) of
the Exchange Act or Rule 16a-1(a)(1) promulgated under the Exchange Act.
(b) This Section 11 shall not restrict
the number of shares of Common Stock which a Holder may receive or beneficially own in order to determine the amount of securities or
other consideration that such Holder may receive in the event of a Fundamental Transaction as contemplated in Section 9(c) of
this Warrant.
12. No Fractional Shares. No fractional
Warrant Shares will be issued in connection with any exercise of this Warrant. In lieu of any fractional shares that would otherwise be
issuable, the number of Warrant Shares to be issued shall be rounded down to the next whole number and the Company shall pay the Holder
in cash the fair market value (based on the Closing Sale Price) for any such fractional shares.
13. Notices. Any and all notices or other
communications or deliveries hereunder (including, without limitation, any Exercise Notice) shall be in writing and shall be deemed given
and effective on the earliest of (i) the date of transmission, if such notice or communication is delivered via confirmed email prior
to 5:30 P.M., New York City time, on a Trading Day, (ii) the next Trading Day after the date of transmission, if such notice or communication
is delivered via confirmed e-mail on a day that is not a Trading Day or later than 5:30 P.M., New York City time, on any Trading Day,
(iii) the Trading Day following the date of mailing, if sent by nationally recognized overnight courier service specifying next business
day delivery, or (iv) upon actual receipt by the Person to whom such notice is required to be given, if by hand delivery. The addresses
and e-mail addresses for such communications shall be:
If to the Company:
Rapid Micro Biosystems, Inc.
25 Hartwell Avenue
Lexington, MA 02421
Attention: Chief Executive Officer
Telephone: (978) 349-3200
Email: [___]
If to the Holder, to its address or e-mail address set forth herein
or on the books and records of the Company.
Or, in each of the above instances, to such other
address or e-mail address as the recipient party has specified by written notice given to each other party at least five (5) days
prior to the effectiveness of such change.
14. Warrant Agent. The Company shall initially
serve as warrant agent under this Warrant. Upon ten (10) days’ notice to the Holder, the Company may appoint a new warrant
agent. Any corporation into which the Company or any new warrant agent may be merged or any corporation resulting from any consolidation
to which the Company or any new warrant agent shall be a party or any corporation to which the Company or any new warrant agent transfers
substantially all of its corporate trust or shareholders services business shall be a successor warrant agent under this Warrant without
any further act. Any such successor warrant agent shall promptly cause notice of its succession as warrant agent to be mailed (by first
class mail, postage prepaid) to the Holder at the Holder’s last address as shown on the Warrant Register.
15. Miscellaneous.
(a) No Rights as a Stockholder. The
Holder, solely in such Person’s capacity as a holder of this Warrant, shall not be entitled to vote or receive dividends or be deemed
the holder of share capital of the Company for any purpose, nor shall anything contained in this Warrant be construed to confer upon the
Holder, solely in such Person’s capacity as the Holder of this Warrant, any of the rights of a stockholder of the Company or any
right to vote, give or withhold consent to any corporate action (whether any reorganization, issue of stock, reclassification of stock,
consolidation, merger, amalgamation, conveyance or otherwise), receive notice of meetings, receive dividends or subscription rights, or
otherwise, prior to the issuance to the Holder of the Warrant Shares which such Person is then entitled to receive upon the due exercise
of this Warrant. In addition, nothing contained in this Warrant shall be construed as imposing any liabilities on the Holder to purchase
any securities (upon exercise of this Warrant or otherwise) or as a stockholder of the Company, whether such liabilities are asserted
by the Company or by creditors of the Company.
(b) Authorized Shares. Except and
to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending its
certificate or articles of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue
or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this
Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may
be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the generality
of the foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor upon such
exercise immediately prior to such increase in par value, (ii) take all such action as may be necessary or appropriate in order that
the Company may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant, and (iii) use
commercially reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction
thereof as may be necessary to enable the Company to perform its obligations under this Warrant.
(c) Successors and Assigns. Subject
to compliance with applicable securities laws, this Warrant may be assigned by the Holder. This Warrant may not be assigned by the Company
without the written consent of the Holder, except to a successor in the event of a Fundamental Transaction. This Warrant shall be binding
on and inure to the benefit of the Company and the Holder and their respective successors and assigns. Subject to the preceding sentence,
nothing in this Warrant shall be construed to give to any Person other than the Company and the Holder any legal or equitable right, remedy
or cause of action under this Warrant. This Warrant may be amended only in writing signed by the Company and the Holder, or their successors
and assigns.
(d) Amendment and Waiver. Except as
otherwise provided herein, this Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company
and the Holder; provided that, Section 11(a) may not be modified or amended.
(e) Acceptance. Receipt of this Warrant by the Holder shall
constitute acceptance of and agreement to all of the terms and conditions contained herein.
(f) Governing Law; Jurisdiction. ALL
QUESTIONS CONCERNING THE CONSTRUCTION, VALIDITY, ENFORCEMENT AND INTERPRETATION OF THIS WARRANT SHALL BE GOVERNED BY AND CONSTRUED AND
ENFORCED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO THE PRINCIPLES OF CONFLICTS OF LAW THEREOF. EACH OF THE
COMPANY AND THE HOLDER HEREBY IRREVOCABLY SUBMITS TO THE EXCLUSIVE JURISDICTION OF THE STATE AND FEDERAL COURTS SITTING IN THE CITY OF
NEW YORK, BOROUGH OF MANHATTAN, FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION HEREWITH OR WITH ANY TRANSACTION CONTEMPLATED
HEREBY OR DISCUSSED HEREIN (INCLUDING WITH RESPECT TO THE ENFORCEMENT OF ANY OF THE TRANSACTION DOCUMENTS), AND HEREBY IRREVOCABLY WAIVES,
AND AGREES NOT TO ASSERT IN ANY SUIT, ACTION OR PROCEEDING, ANY CLAIM THAT IT IS NOT PERSONALLY SUBJECT TO THE JURISDICTION OF ANY SUCH
COURT. EACH OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY WAIVES PERSONAL SERVICE OF PROCESS AND CONSENTS TO PROCESS BEING SERVED IN
ANY SUCH SUIT, ACTION OR PROCEEDING BY MAILING A COPY THEREOF VIA REGISTERED OR CERTIFIED MAIL OR OVERNIGHT DELIVERY (WITH EVIDENCE OF
DELIVERY) TO SUCH PERSON AT THE ADDRESS IN EFFECT FOR NOTICES TO IT AND AGREES THAT SUCH SERVICE SHALL CONSTITUTE GOOD AND SUFFICIENT
SERVICE OF PROCESS AND NOTICE THEREOF. NOTHING CONTAINED HEREIN SHALL BE DEEMED TO LIMIT IN ANY WAY ANY RIGHT TO SERVE PROCESS IN ANY
MANNER PERMITTED BY LAW. EACH OF THE COMPANY AND THE HOLDER HEREBY WAIVES ALL RIGHTS TO A TRIAL BY JURY.
(g) Headings. The headings herein
are for convenience only, do not constitute a part of this Warrant and shall not be deemed to limit or affect any of the provisions hereof.
(h) Severability. In case any one
or more of the provisions of this Warrant shall be invalid or unenforceable in any respect, the validity and enforceability of the remaining
terms and provisions of this Warrant shall not in any way be affected or impaired thereby, and the Company and the Holder will attempt
in good faith to agree upon a valid and enforceable provision which shall be a commercially reasonable substitute therefor, and upon so
agreeing, shall incorporate such substitute provision in this Warrant.
REMAINDER OF PAGE INTENTIONALLY LEFT BLANK.
IN WITNESS WHEREOF, the Company has caused this Warrant to be duly
executed by its authorized officer as of the date first indicated above.
RAPID MICRO BIOSYSTEMS, INC.
By:
Name:
Robert Spignesi
Title:
President and Chief Executive Officer
SCHEDULE 1
FORM OF EXERCISE NOTICE
[To be executed by the Holder to purchase shares
of Common Stock under the Warrant]
Ladies and Gentlemen: (1) The undersigned is the Holder of Warrant
No. ___ (the “Warrant”) issued by Rapid Micro Biosystems, Inc., a Delaware corporation (the “Company”).
Capitalized terms used herein and not otherwise defined herein have the respective meanings set forth in the Warrant.
(2)
The undersigned hereby exercises its right to purchase ___________ Warrant Shares pursuant to the Warrant.
(3)
The Holder intends that payment of the Exercise Price shall be made as a “Cashless Exercise” under Section 10 of the Warrant.
(4)
Pursuant to this Exercise Notice, the Company shall deliver to the Holder Warrant Shares determined in accordance with the terms of the Warrant. The Warrant Shares shall be delivered to the following DWAC Account Number:
(5)
By its delivery of this Exercise Notice, the undersigned represents and warrants to the Company that in giving effect to the exercise evidenced hereby the Holder will not beneficially own in excess of the number of shares of Common Stock (as determined in accordance with Section 13(d) of the Securities Exchange Act of 1934, as amended) permitted to be owned under Section 11(a) of the Warrant to which this notice relates.
Dated:
Name of Holder:
By:
Name:
Title:
(Signature must conform in all respects to name of Holder as specified
on the face of the Warrant)
EX-4.2 — EXHIBIT 4.2
EX-4.2
Filename: tm2614922d1_ex4-2.htm · Sequence: 4
Exhibit 4.2
RAPID MICRO BIOSYSTEMS, INC.
WARRANT TO PURCHASE COMMON STOCK OR PRE-FUNDED
WARRANTS
Number of Shares: [_________] (subject to adjustment)
Warrant No. CW-[___]
Original Issue Date: May [___], 2026
Rapid Micro Biosystems, Inc., a Delaware
corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, [___________] or its registered assigns (the “Holder”) is entitled, subject to the
terms set forth below, to purchase from the Company up to a total of [______] shares of Class A common stock, $0.01 par value per
share (the “Common Stock”), of the Company (each such share, a “Warrant Share” and all such shares,
the “Warrant Shares”) at an exercise price per share equal to $2.07 (the “Exercise Price”), in each
case as adjusted from time to time as provided in Section 9, upon surrender of this Warrant to Purchase Common Stock or Pre-Funded
Warrants (including any Warrants to Purchase Common Stock issued in exchange, transfer or replacement hereof, the “Warrant”)
at any time and from time to time on or after [_], 20261 (the “Initial Exercise Date”) and on or prior
to 5:00 p.m. (New York City time) on May, [_], 2027 (the “Termination Date”) but not thereafter, subject to the
following terms and conditions:
1. Definitions. For purposes of this Warrant,
the following terms shall have the following meanings: (a) “Affiliate” means any Person directly or indirectly
controlled by, controlling or under common control with, a Holder, as such terms are used in and construed under Rule 405 under the
Securities Act, but only for so long as such control shall continue.
(b) “Commission” means
the United States Securities and Exchange Commission.
(c) “Closing Sale Price”
means, for any security as of any date, the last trade price for such security on the Principal Trading Market for such security, as reported
by Bloomberg L.P., or, if such Principal Trading Market begins to operate on an extended hours basis and does not designate the last trade
price, then the last trade price of such security prior to 4:00 P.M., New York City time, as reported by Bloomberg L.P., or if the security
is not listed for trading on a national securities exchange or other trading market on the relevant date, the last quoted bid price for
the security in the over-the-counter market on the relevant date as reported by OTC Markets Group Inc. (or a similar organization or agency
succeeding to its functions of reporting prices). If the Closing Sale Price cannot be calculated for a security on a particular date on
any of the foregoing bases, the Closing Sale Price of such security on such date shall be the fair market value as mutually determined
by the Company and the Holder. If the Company and the Holder are unable to agree upon the fair market value of such security, then the
Board of Directors of the Company shall use its good faith judgment to determine the fair market value. The Board of Directors’
determination shall be binding upon all parties absent demonstrable error. All such determinations shall be appropriately adjusted for
any stock dividend, stock split, stock combination or other similar transaction during the applicable calculation period.
(d) “Equity Conditions”
will be deemed to be satisfied as of any date if all of the following conditions are satisfied as of such date: (A) the Holder is
not in possession of any material non-public information; (B) such shares will satisfy Section 8; (C) no pending, proposed
or intended Fundamental Transaction has occurred that has not been abandoned, terminated or consummated; and (D) no delisting or
suspension by the principal, in terms of volume, Principal Trading Market on which the Company is then listed or traded has been threatened
(with a reasonable prospect of delisting or suspension occurring after giving effect to all applicable notice, appeal, compliance and
hearing periods).
(e) “Forced Exercise Trigger”
means (i) the VWAP meets or exceeds $3.85 (subject to appropriate adjustment in the event of any stock dividend, stock split, combination
or other similar recapitalization, but excluding any adjustments pursuant to the provisions of this Warrant) for ten (10) consecutive
Trading Days, (ii) the average daily trading volume of the Company’s Common Stock on the Principal Trading Market meets or
exceeds 100% of the Warrant Shares subject to such exercise for ten (10) consecutive Trading Days and (iii) the Common Stock
continues to be listed on the Nasdaq Capital Market.
1 NTD: Six months from Original Issue Date.
(f) “Principal Trading Market”
means the national securities exchange or other trading market on which the Common Stock is primarily listed on and quoted for trading,
which, as of the Original Issue Date, shall be the Nasdaq Capital Market.
(g) “Registration Statement”
means the Company’s Registration Statement on Form S-3 (File No 333- 276081), as filed with the Commission on December 15,
2023 and declared effective on December 26, 2023.
(h) “Securities Act” means
the Securities Act of 1933, as amended.
(i) “Standard Settlement Period”
means the standard settlement period, expressed in a number of Trading Days, for the Company’s primary trading market or quotation
system with respect to the Common Stock that is in effect on the date of delivery of an applicable Exercise Notice, which as of the Original
Issue Date is “T+1”.
(j) “Trading Day” means
any weekday on which the Principal Trading Market is open for trading. If the Common Stock is not listed or admitted for trading, “Trading
Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the United States or any day on
which banking institutions in New York City are authorized or required by law or other governmental action to close.
(k) “Trading Market” means
any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date in question: the NYSE
American, the Nasdaq Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market or the New York Stock Exchange (or any
successors to any of the foregoing).
(l) “Transfer Agent” means
Computershare Trust Company, N.A., the Company’s transfer agent and registrar for the Common Stock, and any successor appointed
in such capacity.
(m) “VWAP” means, for
any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed or quoted
on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date) on the
Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg (based on a Trading Day from 9:30 a.m. (New
York City time) to 4:02 p.m. (New York City time)), (b) if the OTCQB Venture Market (“OTCQB”) or the OTCQX Best
Market (“OTCQX”) is not a Trading Market, the volume weighted average price of the Common Stock for such date (or the nearest
preceding date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then listed or quoted for trading on OTCQB or OTCQX
and if prices for the Common Stock are then reported on The Pink Open Market (or a similar organization or agency succeeding to its functions
of reporting prices), the most recent bid price per share of the Common Stock so reported, or (d) in all other cases, the fair market
value of a share of Common Stock as determined by an independent appraiser selected in good faith by the holders of a majority in interest
of the Warrants then outstanding and reasonably acceptable to the Company, the fees and expenses of which shall be paid by the Company.
2. Issuance of Securities; Registration of
Warrants. The Warrant, as initially issued by the Company, is offered and sold pursuant to the Registration Statement. As of the Original
Issue Date, the Warrant Shares are issuable under the Registration Statement. Accordingly, the Warrant and, assuming issuance pursuant
to the Registration Statement or an exchange meeting the requirements of Section 3(a)(9) of the Securities Act as in effect
on the Original Issue Date, the Warrant Shares, are not “restricted securities” under Rule 144 promulgated under the
Securities Act. The Company shall register ownership of this Warrant, upon records to be maintained by the Company for that purpose (the
“Warrant Register”), in the name of the record Holder (which shall include the initial Holder or, as the case may be,
any assignee to which this Warrant is assigned hereunder) from time to time. The Company may deem and treat the registered Holder of this
Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder, and for all other purposes,
absent actual notice to the contrary.
3. Registration of Transfers. Subject to
compliance with all applicable securities laws, the Company shall, or will cause its Transfer Agent to, register the transfer of all or
any portion of this Warrant in the Warrant Register, upon surrender of this Warrant, and payment for all applicable transfer taxes (if
any). Upon any such registration or transfer, a new warrant to purchase Common Stock in substantially the form of this Warrant (any such
new warrant, a “New Warrant”) evidencing the portion of this Warrant so transferred shall be issued to the transferee,
and a New Warrant evidencing the remaining portion of this Warrant not so transferred, if any, shall be issued to the transferring Holder.
The acceptance of the New Warrant by the transferee thereof shall be deemed the acceptance by such transferee of all of the rights and
obligations in respect of the New Warrant that the Holder has in respect of this Warrant. The Company shall, or will cause its Transfer
Agent to, prepare, issue and deliver at the Company’s own expense any New Warrant under this Section 3. Until due presentment
for registration of transfer, the Company may treat the registered Holder hereof as the owner and holder for all purposes, and the Company
shall not be affected by any notice to the contrary.
4. Exercise and Duration of Warrants.
(a) All or any part of this Warrant shall
be exercisable by the registered Holder in any manner permitted by this Warrant (including Section 11) at any time and from time
to time on or after the Initial Exercise Date and on or before the Termination Date.
(b) The Holder may exercise this Warrant
by delivering to the Company (i) an exercise notice, in the form attached as Schedule 1 hereto (the “Exercise Notice”),
completed and duly signed, of the Holder’s election to exercise this Warrant for, at the Holder’s sole discretion, either
(A) Warrant Shares or (B) Pre-Funded Warrants to purchase a number of shares of Common Stock equal to the number of Warrant
Shares as to which this Warrant is being exercised in substantially the same form of Pre-Funded Warrant included in the Company’s
Current Report on Form 8-K filed with the Securities and Exchange Commission on May [18], 2026 (“Pre-Funded Warrants”)
with an exercise price of $0.01 per share of Common Stock and (ii) payment of the Exercise Price for the number of Warrant Shares
as to which this Warrant is being exercised (which may take the form of a “cashless exercise” if permitted by Section 10
below and so indicated in the Exercise Notice pursuant to Section 10 below), or, if this Warrant is being exercised for Pre-Funded
Warrants, the aggregate Exercise Price, less $0.01, multiplied by the number of Warrant Shares as to which this Warrant is being exercised.
The date on which Exercise Notice is delivered to the Company (as determined in accordance with the notice provisions hereof) is an “Exercise
Date.” The Holder shall not be required to deliver the original Warrant in order to effect an exercise hereunder. Execution
and delivery of the Exercise Notice shall have the same effect as cancellation of the original Warrant and issuance of a New Warrant evidencing
the right to purchase the remaining number of Warrant Shares, if any. The Holder and any assignee, by acceptance of this Warrant, acknowledge
and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the Warrant Shares and Pre-Funded
Warrants hereunder, the number of Warrant Shares and Pre-Funded Warrants available for purchase hereunder at any given time may be less
than the amount stated on the face hereof.
(c) Forced Exercise.
(A) If the Forced Exercise Trigger occurs,
then the Company may, at its sole discretion, deliver written notice to the Holder (a “Forced Exercise Notice”) requiring
the Holder to exercise all or any portion of this Warrant (a “Forced Exercise”) (i) for cash, if at the time the
Forced Exercise Notice is delivered there is an effective registration statement registering, and the prospectus contained therein is
available for, the issuance or resale of the Warrant Shares, or (ii) otherwise, by cashless exercise pursuant to Section 10,
and certifying that the Equity Conditions have been satisfied on the date the Forced Exercise Notice was delivered to the Holder; provided
that (x) no Forced Exercise will be effected unless the Equity Conditions are satisfied on each Trading Day from the date of
the Forced Exercise Notice until the corresponding Warrant Shares or Pre-Funded Warrants, as applicable, are delivered by the Company,
(y) if the Company receives an Exercise Notice prior to the date the Company delivers a Forced Exercise Notice and any Warrant Shares
or Pre-Funded Warrants, as applicable, due thereunder remain undelivered by the Company, the Forced Exercise may not occur until after
such Warrant Shares or Pre-Funded Warrants, as applicable, are delivered to the Holder and (z) the number of Warrant Shares or Pre-Funded
Warrants, as applicable, subject to any Forced Exercise shall be reduced, on a share-for-share basis, by the number of Warrant Shares
or Pre-Funded Warrants, as applicable, that the Holder exercised pursuant to any voluntary Exercise Notices delivered prior to the Forced
Exercise Date. The Company may not deliver more than one Forced Exercise Notice with respect to this Warrant in any rolling ten (10) Trading
Day period.
(B) The Forced Exercise shall be effective
(i) in the event the Warrant is exercised by cashless exercise, as of the date the Forced Exercise Notice is delivered to the Holder
or (ii) in the event the Warrant is exercised by payment of cash, the date upon the Company’s receipt of such cash payment,
which shall be no later than five (5) Trading Days following the date the Forced Exercise Notice is delivered to the Holder (the
“Forced Exercise Date”), and the Company shall deliver the applicable Warrant Shares or Pre-Funded Warrants, as applicable,
as if the Holder had delivered an Exercise Notice on the Forced Exercise Date using the applicable settlement method.
(C) If the Company delivers a Forced Exercise
Notice to any Holder, the Company shall simultaneously deliver a Forced Exercise Notice to each other holder of Warrants issued pursuant
to that certain Underwriting Agreement, dated as of May [18], 2026, by and among the Company, TD Securities (USA) LLC, and Lake Street
Capital Markets, LLC, requiring each such holder to exercise all or any corresponding portion of its respective warrant on the same terms
and conditions as set forth in this Section 4(c).
5. Delivery of Warrant Shares.
(a) If this Warrant is being exercised for
Warrant Shares, upon exercise of this Warrant, the Company shall, or shall cause the Transfer Agent to, promptly (but in no event later
than the number of Trading Days comprising the Standard Settlement Period following the Exercise Date), upon the request of the Holder,
credit such aggregate number of shares of Common Stock to which the Holder is entitled pursuant to such exercise to the Holder’s
or its designee’s balance account with The Depository Trust Company (“DTC”) through its Deposit Withdrawal Agent
Commission system, or if the Transfer Agent is not participating in the Fast Automated Securities Transfer Program or if the certificates
are required to bear a legend regarding restriction on transferability, issue and dispatch by overnight courier to the address as specified
in the Exercise Notice, a certificate, registered in the Company’s share register in the name of the Holder or its designee, for
the number of shares of Common Stock to which the Holder is entitled pursuant to such exercise. If this Warrant is being exercised for
Pre-Funded Warrants, the Company shall issue and dispatch by overnight courier to the address specified in the Exercise Notice, Pre-Funded
Warrants to purchase a number of shares of Common Stock equal to the number of Warrant Shares with respect to which this Warrant is being
exercised. The Holder, or any natural person or legal entity (each, a “Person”) so designated by the Holder to receive
Warrant Shares or Pre-Funded Warrants, shall be deemed to have become the holder of record of such Warrant Shares or Pre-Funded Warrants
as of the Exercise Date, irrespective of the date such Warrant Shares are credited to the Holder’s DTC account or the date of delivery
of the certificates evidencing such Warrant Shares or Pre-Funded Warrants, as the case may be.
(b) If this Warrant is being exercised for
Warrant Shares, if the Company fails to deliver to the Holder a certificate representing the required number of Warrant Shares in the
manner required pursuant to Section 5(a) or fails to credit, or cause the Transfer Agent to credit, the Holder’s
DTC account for such number of Warrant Shares to which the Holder is entitled within the Standard Settlement Period following the Exercise
Date, and if after such Standard Settlement Period and prior to the receipt of such Warrant Shares, the Holder purchases (in an open market
transaction or otherwise) shares of Common Stock to deliver in satisfaction of a sale by the Holder of the Warrant Shares which the Holder
anticipated receiving upon such exercise (a “Buy-In”), then the Company shall, within one (1) Trading Day after
the Holder’s request promptly honor its obligation to deliver to the Holder a certificate or certificates representing such Warrant
Shares and pay cash to the Holder in an amount equal to the excess (if any) of Holder’s total purchase price (including brokerage
commissions, if any) for the shares of Common Stock so purchased in the Buy-In less the product of (A) the number of shares of Common
Stock purchased in the Buy-In, times (B) the Closing Sale Price of a share of Common Stock on the Exercise Date.
(c) To the extent permitted by law and subject
to Section 5(b), the Company’s obligations to issue and deliver Warrant Shares or Pre-Funded Warrants, as the case may be,
in accordance with and subject to the terms hereof (including the limitations set forth in Section 11 below) are absolute and unconditional,
irrespective of any action or inaction by the Holder to enforce the same, any waiver or consent with respect to any provision hereof,
the recovery of any judgment against any Person or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation
or termination, or any breach or alleged breach by the Holder or any other Person of any obligation to the Company or any violation or
alleged violation of law by the Holder or any other Person, and irrespective of any other circumstance that might otherwise limit such
obligation of the Company to the Holder in connection with the issuance of Warrant Shares or Pre-Funded Warrants. Subject to Section 5(b),
nothing herein shall limit the Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including,
without limitation, a decree of specific performance and/or injunctive relief with respect to the Company’s failure to timely deliver
shares of Common Stock or Pre-Funded Warrants upon exercise of the Warrant as required pursuant to the terms hereof.
6. Charges, Taxes and Expenses. Issuance
and delivery of shares of Common Stock upon exercise of this Warrant shall be made without charge to the Holder for any issue or transfer
tax, transfer agent fee or other incidental tax or expense (excluding any applicable stamp duties) in respect of the issuance of such
shares, all of which taxes and expenses shall be paid by the Company; provided, however, that the Company shall not be required
to pay any tax that may be payable in respect of any transfer involved in the registration of any Warrant Shares or the Warrants in a
name other than that of the Holder or an Affiliate thereof. The Holder shall be responsible for all other tax liability that may arise
as a result of holding or transferring this Warrant or receiving Warrant Shares upon exercise hereof.
7. Replacement of Warrant. If this Warrant
is mutilated, lost, stolen or destroyed, the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation
hereof, or in lieu of and substitution for this Warrant, a New Warrant, but only upon receipt of evidence reasonably satisfactory to the
Company of such loss, theft or destruction (in such case) and, in each case, a customary and reasonable contractual indemnity, if requested
by the Company. Applicants for a New Warrant under such circumstances shall also comply with such other reasonable regulations and procedures
and pay such other reasonable third-party costs as the Company may prescribe. If a New Warrant is requested as a result of a mutilation
of this Warrant, then the Holder shall deliver such mutilated Warrant to the Company as a condition precedent to the Company’s obligation
to issue the New Warrant.
8. Reservation of Warrant Shares. The Company
covenants that it will, at all times while this Warrant is outstanding, reserve and keep available out of the aggregate of its authorized
but unissued and otherwise unreserved Common Stock, solely for the purpose of enabling it to issue Warrant Shares upon exercise of this
Warrant as herein provided, the number of Warrant Shares that are initially issuable and deliverable upon the exercise of this entire
Warrant, free from preemptive rights or any other contingent purchase rights of persons other than the Holder (taking into account the
adjustments and restrictions of Section 9). The Company covenants that all Warrant Shares so issuable and deliverable shall, upon
issuance and the payment of the applicable Exercise Price in accordance with the terms hereof, be duly and validly authorized, issued
and fully paid and non-assessable. The Company will take all such action as may be reasonably necessary to assure that such shares of
Common Stock may be issued as provided herein without violation of any applicable law or regulation, or of any requirements of any securities
exchange or automated quotation system upon which the Common Stock may be listed. The Company further covenants that it will not, without
the prior written consent of the Holder, take any actions to increase the par value of the Common Stock at any time while this Warrant
is outstanding.
9. Certain Adjustments. The Exercise Price
and number of Warrant Shares issuable upon exercise of this Warrant (the “Number of Warrant Shares”) are subject to
adjustment from time to time as set forth in this Section 9.
(a) Stock Dividends and Splits. If
the Company, at any time while this Warrant is outstanding, (i) pays a stock dividend on its Common Stock or otherwise makes a distribution
on any class of capital stock that is payable in shares of Common Stock, (ii) subdivides its outstanding shares of Common Stock into
a larger number of shares of Common Stock, (iii) combines its outstanding shares of Common Stock into a smaller number of shares
of Common Stock or (iv) issues by reclassification of shares of capital stock any additional shares of Common Stock of the Company,
then in each such case the Number of Warrant Shares shall be multiplied by a fraction, the numerator of which shall be the number of shares
of Common Stock outstanding immediately after such event and the denominator of which shall be the number of shares of Common Stock outstanding
immediately before such event. Any adjustment made pursuant to clause (i) of this paragraph shall become effective immediately after
the record date for the determination of stockholders entitled to receive such dividend or distribution, provided, however, that if such
record date shall have been fixed and such dividend is not fully paid on the date fixed therefor, the Number of Warrant Shares shall be
recomputed accordingly as of the close of business on such record date and thereafter the Number of Warrant Shares shall be adjusted pursuant
to this paragraph as of the time of actual payment of such dividends. Any adjustment pursuant to clause (ii), (iii) or (iv) of
this paragraph shall become effective immediately after the effective date of such subdivision, combination or issuance.
(b) Pro Rata Distributions. During
such time as this Warrant is outstanding, if the Company shall declare or make any dividend or other distribution of its assets (or rights
to acquire its assets) to holders of shares of Common Stock, by way of return of capital or otherwise (including, without limitation,
any distribution of cash, stock or other securities, property or options by way of a dividend, spin off, reclassification, corporate rearrangement,
scheme of arrangement or other similar transaction) (a “Distribution”), at any time after the issuance of this Warrant,
then, in each such case, the Holder shall be entitled to participate in such Distribution to the same extent that the Holder would have
participated therein if the Holder had held the number of shares of Common Stock acquirable upon complete exercise of this Warrant (without
regard to any limitations on exercise hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the
date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders of shares
of Common Stock are to be determined for the participation in such Distribution (provided, however, that to the extent that
the Holder’s right to participate in any such Distribution would result in the Holder exceeding the Beneficial Ownership Limitation,
then the Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership of any shares
of Common Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance for the
benefit of the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership
Limitation).
(c) Fundamental Transactions. If,
at any time while this Warrant is outstanding (i) the Company effects any merger or consolidation of the Company with or into another
Person, in which the Company is not the surviving entity or in which the stockholders of the Company immediately prior to such merger
or consolidation do not own, directly or indirectly, at least 50% of the voting power of the surviving entity immediately after such merger
or consolidation, (ii) the Company effects any sale, transfer or disposition to another Person of all or substantially all of its
assets in one transaction or a series of related transactions, (iii) pursuant to any tender offer or exchange offer (whether by the
Company or another Person), holders of capital stock tender shares representing more than 50% of the voting power of the capital stock
of the Company and the Company or such other Person, as applicable, accepts such tender for payment, (iv) the Company consummates
a stock purchase agreement or other business combination (including, without limitation, a reorganization, recapitalization, spin-off
or scheme of arrangement) with another Person whereby such other Person acquires more than the 50% of the voting power of the capital
stock of the Company (except for any such transaction in which the stockholders of the Company immediately prior to such transaction maintain,
in substantially the same proportions, the voting power of such Person immediately after the transaction) or (v) the Company effects
any reclassification of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively converted
into or exchanged for other securities, cash or property (other than as a result of a subdivision or combination of shares of Common Stock
covered by Section 9(a) above) (in any such case, a “Fundamental Transaction”), then following such Fundamental
Transaction the Holder shall have the right to receive, upon exercise of this Warrant, the same amount and kind of securities, cash or
property as it would have been entitled to receive upon the occurrence of such Fundamental Transaction if it had been, immediately prior
to such Fundamental Transaction, the holder of the Number of Warrant Shares without regard to any limitations on exercise contained herein
(in the case of clause (iii) above, assuming it had tendered, and the offeror had accepted, such Warrant Shares) (the “Alternate
Consideration”). The Company shall not effect any Fundamental Transaction in which the Company is not the surviving entity or
the Alternate Consideration includes securities of another Person unless (i) the Alternate Consideration is solely cash and the Company
provides for the simultaneous “cashless exercise” of this Warrant pursuant to Section 10 below or (ii) prior to
or simultaneously with the consummation thereof, any successor to the Company, surviving entity or other Person (including any purchaser
of assets of the Company) shall assume the obligation to deliver to the Holder such Alternate Consideration as, in accordance with the
foregoing provisions, the Holder may be entitled to receive, and the other obligations under this Warrant. The provisions of this paragraph
(c) shall similarly apply to subsequent transactions analogous of a Fundamental Transaction type.
The terms of any agreement pursuant to which a
Fundamental Transaction is effected shall include terms requiring any such successor or surviving entity to comply with the provisions
of this Section 9(c) and insuring that this Warrant (or any such replacement security) will be similarly adjusted upon
any subsequent Fundamental Transaction. The Company shall cause any successor entity in a Fundamental Transaction in which the Company
is not the survivor (the “Successor Entity”) to assume in writing all of the obligations of the Company under this
Warrant in accordance with the provisions of this Section 9(c) pursuant to written agreements in form and substance reasonably
satisfactory to the Holder and approved by the Holder (without unreasonable delay) prior to such Fundamental Transaction and shall, at
the option of the Holder, deliver to the Holder in exchange for this Warrant a security of the Successor Entity evidenced by a written
instrument substantially similar in form and substance to this Warrant which is exercisable for a corresponding number of shares of capital
stock of such Successor Entity (or its parent entity) equivalent to the shares of Common Stock acquirable and receivable upon exercise
of this Warrant (without regard to any limitations on the exercise of this Warrant) prior to such Fundamental Transaction, and with an
exercise price which applies the exercise price hereunder to such shares of capital stock (but taking into account the relative value
of the shares of Common Stock pursuant to such Fundamental Transaction and the value of such shares of capital stock, such adjustments
to the number of shares of capital stock and such exercise price being for the purpose of protecting the economic value of this Warrant
immediately prior to the consummation of such Fundamental Transaction), and which is reasonably satisfactory in form and substance to
the Holder. Upon the occurrence of any such Fundamental Transaction, the Successor Entity shall succeed to, and be substituted for the
Company (so that from and after the date of such Fundamental Transaction, the provisions of this Warrant referring to the “Company”
shall refer instead to the Successor Entity), and may exercise every right and power of the Company and shall assume all of the obligations
of the Company under this Warrant with the same effect as if such Successor Entity had been named as the Company herein. Notwithstanding
the foregoing, and without limiting Section 11 hereof, the Holder may elect, at its sole option, by delivery of written notice
to the Company to waive this Section 9(c) to permit a Fundamental Transaction without the assumption of this Warrant.
(d) Exercise Price. Simultaneously
with any adjustment to the Number of Warrant Shares pursuant to Section 9 the Exercise Price shall be increased or decreased proportionately,
so that after such adjustment the aggregate Exercise Price payable hereunder for the increased or decreased Number of Warrant Shares shall
be the same as the aggregate Exercise Price in effect immediately prior to such adjustment. Notwithstanding the foregoing, in no event
may the Exercise Price be adjusted below the par value of the Common Stock then in effect.
(e) Calculations. All calculations
under this Section 9 shall be made to the nearest one-hundredth of one cent or the nearest whole share, as applicable.
(f) Notice of Adjustments. Upon the
occurrence of each adjustment pursuant to this Section 9, the Company at its expense will promptly compute such adjustment, in good
faith, in accordance with the terms of this Warrant and prepare a certificate setting forth such adjustment, including a statement of
the adjusted Exercise Price and adjusted number or type of Warrant Shares or other securities issuable upon exercise of this Warrant
(as applicable), describing the transactions giving rise to such adjustments and showing in detail the facts upon which such adjustment
is based. Upon written request, the Company will promptly deliver a copy of each such certificate to the Holder and to the Transfer Agent.
(g) Notice of Corporate Events. If,
while this Warrant is outstanding, the Company (i) declares a dividend or any other distribution of cash, securities or other property
in respect of its Common Stock, including, without limitation, any granting of rights or warrants to subscribe for or purchase any capital
stock of the Company or any subsidiary, (ii) authorizes or approves, enters into any agreement contemplating or solicits stockholder
approval for any Fundamental Transaction or (iii) authorizes the voluntary dissolution, liquidation or winding up of the affairs
of the Company, then, except if such notice and the contents thereof shall be deemed to constitute material non-public information, the
Company shall deliver to the Holder a notice of such transaction at least ten (10) days prior to the applicable record or effective
date on which a Person would need to hold Common Stock in order to participate in or vote with respect to such transaction; provided,
however, that the failure to deliver such notice or any defect therein shall not affect the validity of the corporate action required
to be described in such notice. In addition, if while this Warrant is outstanding, the Company authorizes or approves, enters into any
agreement contemplating or solicits stockholder approval for any Fundamental Transaction contemplated by Section 9(c), other than
a Fundamental Transaction under clause (iii) of Section 9(c), then, except if such notice and the contents thereof shall be
deemed to constitute material non-public information, the Company shall deliver to the Holder a notice of such Fundamental Transaction
at least ten (10) days prior to the date such Fundamental Transaction is consummated.
(h) Voluntary Adjustment By Company.
Subject to the rules and regulations of the Principal Trading Market, the Company may at any time during the term of this Warrant,
reduce the then-current Exercise Price to any amount and for any period of time deemed appropriate by the board of directors of the Company.
10. Cashless Exercise. If at any time during
the term of this Warrant the Registration Statement or another registration statement registering the issuance of Warrant Shares is, for
any reason, not effective at the time of exercise of this Warrant, this Warrant may be exercised through a “cashless exercise.”
Upon exercise, the Company shall issue to the Holder the number of Warrant Shares in an exchange of securities effected pursuant to Section 3(a)(9) of
the Securities Act as determined as follows:
X = Y [(A-B)/A]
where:
“X” equals the number of Warrant Shares to be issued to
the Holder;
“Y” equals the total number of Warrant Shares with respect
to which this Warrant is then being exercised;
“A” equals the Closing Sale Price per share of Common Stock
as of the Trading Day on the date immediately preceding the Exercise Date; and
“B” equals the Exercise Price per Warrant Share then in
effect on the Exercise Date.
For purposes of Rule 144 promulgated under
the Securities Act, it is intended, understood and acknowledged that the Warrant Shares issued in such a “cashless exercise”
transaction shall be deemed to have been acquired by the Holder, and the holding period for the Warrant Shares shall be deemed to have
commenced, on the Original Issue Date (provided that the Commission continues to take the position that such treatment is proper at the
time of such exercise). In the event that the Registration Statement or another registration statement registering the issuance of Warrant
Shares is, for any reason, not effective at the time of exercise of this Warrant, then this Warrant may only be exercised through a cashless
exercise, as set forth in this Section 10.
Except as otherwise set forth herein, in no event
will the exercise of this Warrant be settled in cash.
11. Limitations on Exercise.
(a) Notwithstanding anything to the contrary
contained herein, the Company shall not effect any exercise of this Warrant (other than for Pre-Funded Warrants), and the Holder shall
not be entitled to exercise this Warrant (other than for Pre-Funded Warrants) (i) if immediately prior to the exercise, the Holder,
its Affiliates and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes
of Section 13(d) of the Exchange Act, beneficially own an aggregate number of shares of Common Stock greater than [4.5] [4.99]
[9.99] % (the “Maximum Percentage”) of the total number of issued and outstanding shares of Common Stock of the Company
without taking into account any Warrant Shares, or (ii) to the extent that immediately following the exercise, the Holder, its Affiliates
and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of
the Exchange Act, would beneficially own in excess of the Maximum Percentage of the number of shares of Common Stock outstanding immediately
after giving effect to the issuance of such shares of Common Stock. Any portion of an exercise that would result in the issuance of shares
in excess of the Maximum Percentage shall be treated as null and void ab initio. For purposes of this Warrant, in determining the number
of outstanding shares of Common Stock, the Holder may rely on the number of outstanding shares of Common Stock as reflected in (x) the
Company’s most recent Form 10-Q or Form 10-K, as the case may be, filed with the Commission prior to the Exercise Date,
(y) a more recent public announcement by the Company or (z) any other notice by the Company or its Transfer Agent setting forth
the number of shares of Common Stock outstanding. Upon the written request of the Holder, the Company shall within three (3) Trading
Days confirm in writing or by electronic mail to the Holder the number of shares of Common Stock then outstanding. In any case, the number
of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company,
including this Warrant, by the Holder since the date as of which such number of outstanding shares of Common Stock was reported. By written
notice to the Company, the Holder may from time to time increase or decrease the Maximum Percentage to any other percentage specified
not in excess of 19.99% specified in such notice; provided that any such increase will not be effective until the sixty-first (61st) day
after such notice is delivered to the Company. For purposes of this Section 11(a), the aggregate number of shares of Common Stock
or voting securities beneficially owned by the Holder and its Affiliates and any other Persons whose beneficial ownership of Common Stock
would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act shall include the shares of Common
Stock issuable upon the exercise of this Warrant with respect to which such determination is being made, but shall exclude the number
of shares of Common Stock which would be issuable upon (x) exercise of the remaining unexercised and non-cancelled portion of this
Warrant by the Holder and (y) exercise or conversion of the unexercised, non-converted or non-cancelled portion of any other securities
of the Company that do not have voting power (including without limitation any securities of the Company which would entitle the holder
thereof to acquire at any time Common Stock, including without limitation any debt, preferred stock, right, option, warrant or other instrument
that is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock),
is subject to a limitation on conversion or exercise analogous to the limitation contained herein and is beneficially owned by the Holder
or any of its Affiliates and other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for
purposes of Section 13(d) of the Exchange Act. For purposes of clarity, the Warrant Shares issuable pursuant to the terms of
this Warrant in excess of the Maximum Percentage shall not be deemed to be beneficially owned by the Holder for any purpose including
for purposes of Section 13(d) of the Exchange Act or Rule 16a-1(a)(1) promulgated under the Exchange Act.
(b) This Section 11 shall not restrict
the number of shares of Common Stock which a Holder may receive or beneficially own in order to determine the amount of securities or
other consideration that such Holder may receive in the event of a Fundamental Transaction as contemplated in Section 9(c) of
this Warrant.
12. No Fractional Shares or Pre-Funded Warrants.
No fractional Warrant Shares or fractional Pre-Funded Warrants will be issued in connection with any exercise of this Warrant. In lieu
of any fractional shares that would otherwise be issuable, the number of Warrant Shares to be issued shall be rounded down to the next
whole number and the Company shall pay the Holder in cash the fair market value (based on the Closing Sale Price) for any such fractional
shares.
13. Notices. Any and all notices or other
communications or deliveries hereunder (including, without limitation, any Exercise Notice) shall be in writing and shall be deemed given
and effective on the earliest of (i) the date of transmission, if such notice or communication is delivered via confirmed email prior
to 5:30 P.M., New York City time, on a Trading Day, (ii) the next Trading Day after the date of transmission, if such notice or communication
is delivered via confirmed e-mail on a day that is not a Trading Day or later than 5:30 P.M., New York City time, on any Trading Day,
(iii) the Trading Day following the date of mailing, if sent by nationally recognized overnight courier service specifying next business
day delivery, or (iv) upon actual receipt by the Person to whom such notice is required to be given, if by hand delivery. The addresses
and e-mail addresses for such communications shall be:
If to the Company:
Rapid Micro Biosystems, Inc.
25 Hartwell Avenue
Lexington, MA 02421
Attention: Chief Executive Officer
Telephone: (978) 349-3200
Email: [___]
If to the Holder, to its address or e-mail address set forth herein
or on the books and records of the Company.
Or, in each of the above instances, to such other
address or e-mail address as the recipient party has specified by written notice given to each other party at least five (5) days
prior to the effectiveness of such change.
14. Warrant Agent. The Company shall initially
serve as warrant agent under this Warrant. Upon ten (10) days’ notice to the Holder, the Company may appoint a new warrant
agent. Any corporation into which the Company or any new warrant agent may be merged or any corporation resulting from any consolidation
to which the Company or any new warrant agent shall be a party or any corporation to which the Company or any new warrant agent transfers
substantially all of its corporate trust or shareholders services business shall be a successor warrant agent under this Warrant without
any further act. Any such successor warrant agent shall promptly cause notice of its succession as warrant agent to be mailed (by first
class mail, postage prepaid) to the Holder at the Holder’s last address as shown on the Warrant Register.
15. Miscellaneous.
(a) No Rights as a Stockholder. Except
as otherwise set forth in this Warrant, the Holder, solely in such Person’s capacity as a holder of this Warrant, shall not be entitled
to vote or receive dividends or be deemed the holder of share capital of the Company for any purpose, nor shall anything contained in
this Warrant be construed to confer upon the Holder, solely in such Person’s capacity as the Holder of this Warrant, any of the
rights of a stockholder of the Company or any right to vote, give or withhold consent to any corporate action (whether any reorganization,
issue of stock, reclassification of stock, consolidation, merger, amalgamation, conveyance or otherwise), receive notice of meetings,
receive dividends or subscription rights, or otherwise, prior to the issuance to the Holder of the Warrant Shares which such Person is
then entitled to receive upon the due exercise of this Warrant. In addition, nothing contained in this Warrant shall be construed as imposing
any liabilities on the Holder to purchase any securities (upon exercise of this Warrant or otherwise) or as a stockholder of the Company,
whether such liabilities are asserted by the Company or by creditors of the Company.
(b) Authorized Shares; Further Assurances.
Except and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation,
amending its certificate or articles of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution,
issue or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of
this Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as
may be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the
generality of the foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor
upon such exercise immediately prior to such increase in par value, (ii) take all such action as may be necessary or appropriate
in order that the Company may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant,
and (iii) use commercially reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory
body having jurisdiction thereof as may be necessary to enable the Company to perform its obligations under this Warrant. Before taking
any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the Exercise
Price, the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from any public
regulatory body or bodies having jurisdiction thereof.
(c) Successors and Assigns. Subject
to compliance with applicable securities laws, this Warrant may be assigned by the Holder. This Warrant may not be assigned by the Company
without the written consent of the Holder, except to a successor in the event of a Fundamental Transaction. This Warrant shall be binding
on and inure to the benefit of the Company and the Holder and their respective successors and assigns. Subject to the preceding sentence,
nothing in this Warrant shall be construed to give to any Person other than the Company and the Holder any legal or equitable right, remedy
or cause of action under this Warrant. This Warrant may be amended only in writing signed by the Company and the Holder, or their successors
and assigns.
(d) Amendment and Waiver. Except as
otherwise provided herein, this Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company
and the Holder; provided that, Section 11(a) may not be modified or amended.
(e) Acceptance. Receipt of this Warrant
by the Holder shall constitute acceptance of and agreement to all of the terms and conditions contained herein.
(f) Governing Law; Jurisdiction.
ALL QUESTIONS CONCERNING THE CONSTRUCTION, VALIDITY, ENFORCEMENT AND INTERPRETATION OF THIS WARRANT SHALL BE GOVERNED BY AND CONSTRUED
AND ENFORCED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO THE PRINCIPLES OF CONFLICTS OF LAW THEREOF. EACH
OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY SUBMITS TO THE EXCLUSIVE JURISDICTION OF THE STATE AND FEDERAL COURTS SITTING IN THE
CITY OF NEW YORK, BOROUGH OF MANHATTAN, FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION HEREWITH OR WITH ANY TRANSACTION
CONTEMPLATED HEREBY OR DISCUSSED HEREIN (INCLUDING WITH RESPECT TO THE ENFORCEMENT OF ANY OF THE TRANSACTION DOCUMENTS), AND HEREBY IRREVOCABLY
WAIVES, AND AGREES NOT TO ASSERT IN ANY SUIT, ACTION OR PROCEEDING, ANY CLAIM THAT IT IS NOT PERSONALLY SUBJECT TO THE JURISDICTION OF
ANY SUCH COURT. EACH OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY WAIVES PERSONAL SERVICE OF PROCESS AND CONSENTS TO PROCESS BEING
SERVED IN ANY SUCH SUIT, ACTION OR PROCEEDING BY MAILING A COPY THEREOF VIA REGISTERED OR CERTIFIED MAIL OR OVERNIGHT DELIVERY (WITH
EVIDENCE OF DELIVERY) TO SUCH PERSON AT THE ADDRESS IN EFFECT FOR NOTICES TO IT AND AGREES THAT SUCH SERVICE SHALL CONSTITUTE GOOD AND
SUFFICIENT SERVICE OF PROCESS AND NOTICE THEREOF. NOTHING CONTAINED HEREIN SHALL BE DEEMED TO LIMIT IN ANY WAY ANY RIGHT TO SERVE PROCESS
IN ANY MANNER PERMITTED BY LAW. EACH OF THE COMPANY AND THE HOLDER HEREBY WAIVES ALL RIGHTS TO A TRIAL BY JURY.
(g) Headings. The headings herein
are for convenience only, do not constitute a part of this Warrant and shall not be deemed to limit or affect any of the provisions hereof.
(h) Severability. In case any one
or more of the provisions of this Warrant shall be invalid or unenforceable in any respect, the validity and enforceability of the remaining
terms and provisions of this Warrant shall not in any way be affected or impaired thereby, and the Company and the Holder will attempt
in good faith to agree upon a valid and enforceable provision which shall be a commercially reasonable substitute therefor, and upon so
agreeing, shall incorporate such substitute provision in this Warrant.
REMAINDER OF PAGE INTENTIONALLY LEFT BLANK.
IN WITNESS WHEREOF, the Company has caused this Warrant to be duly
executed by its authorized officer as of the date first indicated above.
RAPID MICRO BIOSYSTEMS, INC.
By:
Name:
Robert Spignesi
Title:
President and Chief Executive Officer
SCHEDULE 1
FORM OF EXERCISE NOTICE
[To be executed by the Holder to purchase shares
of Common Stock under the Warrant]
Ladies and Gentlemen: (1) The undersigned is the Holder of Warrant
No. ___ (the “Warrant”) issued by Rapid Micro Biosystems, Inc., a Delaware corporation (the “Company”).
Capitalized terms used herein and not otherwise defined herein have the respective meanings set forth in the Warrant.
(2)
The undersigned hereby exercises its right to purchase ___________ Warrant Shares and ___________ Pre-Funded Warrants pursuant to the Warrant.
(3)
The Holder intends that payment of the Exercise Price shall be made as (check one):
☐
Cash Exercise with respect to Warrant Shares
☐
“Cashless Exercise” under Section 10 of the Warrant with respect to Warrant Shares
☐
Cash Exercise with respect to Pre-Funded Warrants
☐
“Cashless Exercise” under Section 10 of the Warrant with respect to Pre-Funded Warrants
(4)
If the Holder has elected a Cash Exercise, the Holder shall pay the sum of $ _____ in immediately available funds to the Company in accordance with the terms of the Warrant.
(5)
Pursuant to this Exercise Notice, the Company shall deliver to the Holder Warrant Shares or Pre-Funded Warrants determined in accordance with the terms of the Warrant. The Warrant Shares shall be delivered to the following DWAC Account Number:
(6)
By its delivery of this Exercise Notice, the undersigned represents and warrants to the Company that in giving effect to the exercise evidenced hereby the Holder will not beneficially own in excess of the number of shares of Common Stock (as determined in accordance with Section 13(d) of the Securities Exchange Act of 1934, as amended) permitted to be owned under Section 11(a) of the Warrant to which this notice relates.
Dated:
Name of Holder:
By:
Name:
Title:
(Signature must conform in all respects to name of Holder as specified
on the face of the Warrant)
EX-4.3 — EXHIBIT 4.3
EX-4.3
Filename: tm2614922d1_ex4-3.htm · Sequence: 5
Exhibit 4.3
RAPID MICRO BIOSYSTEMS, INC.
WARRANT TO PURCHASE COMMON STOCK OR PRE-FUNDED
WARRANTS
Number of Shares: [_________] (subject to adjustment)
Warrant No. CW-[___]
Original Issue Date: May [___], 2026
Rapid Micro Biosystems, Inc., a Delaware
corporation (the “Company”), hereby certifies that, for good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, [___________] or its registered assigns (the “Holder”) is entitled, subject to the
terms set forth below, to purchase from the Company up to a total of [______] shares of Class A common stock, $0.01 par value per
share (the “Common Stock”), of the Company (each such share, a “Warrant Share” and all such shares,
the “Warrant Shares”) at an exercise price per share equal to $2.34 (the “Exercise Price”), in each
case as adjusted from time to time as provided in Section 9, upon surrender of this Warrant to Purchase Common Stock or Pre-Funded
Warrants (including any Warrants to Purchase Common Stock issued in exchange, transfer or replacement hereof, the “Warrant”)
at any time and from time to time on or after [_], 20261 (the “Initial Exercise Date”) and on or prior
to 5:00 p.m. (New York City time) on May [__], 2031 (the “Termination Date”) but not thereafter, subject
to the following terms and conditions:
1. Definitions. For purposes of this Warrant,
the following terms shall have the following meanings:
(a) “Affiliate”
means any Person directly or indirectly controlled by, controlling or under common control with, a Holder, as such terms are used in and
construed under Rule 405 under the Securities Act, but only for so long as such control shall continue.
(b) “Commission”
means the United States Securities and Exchange Commission.
(c) “Common
Stock Equivalents” means any securities of the Company which would entitle the holder thereof to acquire at any time Common
Stock, including any warrant that is at any time exercisable for, or otherwise entitles the holder thereof to receive, Common Stock; but
shall not include any other debt, preferred stock, right, or other instrument.
(d) “Closing
Sale Price” means, for any security as of any date, the last trade price for such security on the Principal Trading Market for
such security, as reported by Bloomberg L.P., or, if such Principal Trading Market begins to operate on an extended hours basis and does
not designate the last trade price, then the last trade price of such security prior to 4:00 P.M., New York City time, as reported by
Bloomberg L.P., or if the security is not listed for trading on a national securities exchange or other trading market on the relevant
date, the last quoted bid price for the security in the over-the-counter market on the relevant date as reported by OTC Markets Group
Inc. (or a similar organization or agency succeeding to its functions of reporting prices). If the Closing Sale Price cannot be calculated
for a security on a particular date on any of the foregoing bases, the Closing Sale Price of such security on such date shall be the fair
market value as mutually determined by the Company and the Holder. If the Company and the Holder are unable to agree upon the fair market
value of such security, then the Board of Directors of the Company shall use its good faith judgment to determine the fair market value.
The Board of Directors’ determination shall be binding upon all parties absent demonstrable error. All such determinations shall
be appropriately adjusted for any stock dividend, stock split, stock combination or other similar transaction during the applicable calculation
period.
(e) “Exempt
Issuance” means the issuance of (a) shares of Common Stock, options, restricted stock units, warrants and/or convertible
securities to employees, consultants, advisors, officers or directors of the Company pursuant to any stock or option plan, agreement or
arrangement duly adopted for such purpose, by a majority of the non-employee members of the Board of Directors or a majority
of the members of a committee of non-employee directors established for such purpose for services rendered to the Company, (b) (i) securities
upon the exercise or exchange of or conversion of any securities issued pursuant to the Registration Statement, and/or (ii) other
securities exercisable or exchangeable for or convertible into shares of Common Stock issued and outstanding on the date hereof, provided
in each case that such securities have not been amended since the date hereof to increase the number of such securities or to decrease
the exercise price, exchange price or conversion price of such securities, (c) securities issued in an underwritten registered offering
not involving a “roadshow,” an offer commonly known as a “block trade”, (d) securities issued pursuant to
acquisitions or strategic transactions approved by the board of directors of the Company, (e) securities issued in connection with
sponsored research, collaboration, technology license, development, distribution, marketing or other similar agreements or strategic partnerships
approved by a majority of the disinterested directors of the Company, and (f) securities issued to banks, equipment lessors or other
financial institutions, or to real property lessors, pursuant to a debt financing, equipment leasing or real property leasing transaction.
1
NTD: Six months from Original Issue Date.
(f) “Participation
Maximum” means an amount equal to 25% of the Subsequent Financing.
(g) “Principal
Trading Market” means the national securities exchange or other trading market on which the Common Stock is primarily listed
on and quoted for trading, which, as of the Original Issue Date, shall be the Nasdaq Capital Market.
(h) “Pro
Rata Portion” means the ratio of (x) the aggregate amount to be paid for securities purchased by the Holder pursuant to
the [_] and (y) the sum of the aggregate amount of securities purchased on [_] pursuant to the [_].
(i) “Registration
Statement” means the Company’s Registration Statement on Form S-3 (File No 333- 276081), as filed with the Commission
on December 15, 2023 and declared effective on December 26, 2023.
(j) “Securities
Act” means the Securities Act of 1933, as amended.
(k) “Standard
Settlement Period” means the standard settlement period, expressed in a number of Trading Days, for the Company’s primary
trading market or quotation system with respect to the Common Stock that is in effect on the d“T+1”.
(l) “Trading
Day” means any weekday on which the Principal Trading Market is open for trading. If the Common Stock is not listed or admitted
for trading, “Trading Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the
United States or any day on which banking institutions in New York City are authorized or required by law or other governmental action
to close.
(m) “Trading
Market” means any of the following ate of delivery of an applicable Exercise Notice, which as of the Original Issue Date is
markets or exchanges on which the Common Stock is listed or quoted for trading on the date in question: the NYSE American, the Nasdaq
Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market or the New York Stock Exchange (or any successors to any of
the foregoing).
(n) “Transfer
Agent” means Computershare Trust Company, N.A., the Company’s transfer agent and registrar for the Common Stock, and any
successor appointed in such capacity.
(o) “VWAP”
means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed
or quoted on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date)
on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg (based on a Trading Day from 9:30 a.m. (New
York City time) to 4:02 p.m. (New York City time)), (b) if the OTCQB Venture Market (“OTCQB”) or the OTCQX Best
Market (“OTCQX”) is not a Trading Market, the volume weighted average price of the Common Stock for such date (or the nearest
preceding date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then listed or quoted for trading on OTCQB or OTCQX
and if prices for the Common Stock are then reported on The Pink Open Market (or a similar organization or agency succeeding to its functions
of reporting prices), the most recent bid price per share of the Common Stock so reported, or (d) in all other cases, the fair market
value of a share of Common Stock as determined by an independent appraiser selected in good faith by the holders of a majority in interest
of the Warrants then outstanding and reasonably acceptable to the Company, the fees and expenses of which shall be paid by the Company.
2. Issuance of Securities; Registration of
Warrants. The Warrant, as initially issued by the Company, is offered and sold pursuant to the Registration Statement. As of the Original
Issue Date, the Warrant Shares are issuable under the Registration Statement. Accordingly, the Warrant and, assuming issuance pursuant
to the Registration Statement or an exchange meeting the requirements of Section 3(a)(9) of the Securities Act as in effect
on the Original Issue Date, the Warrant Shares, are not “restricted securities” under Rule 144 promulgated under the
Securities Act. The Company shall register ownership of this Warrant, upon records to be maintained by the Company for that purpose (the
“Warrant Register”), in the name of the record Holder (which shall include the initial Holder or, as the case may be,
any assignee to which this Warrant is assigned hereunder) from time to time. The Company may deem and treat the registered Holder of this
Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder, and for all other purposes,
absent actual notice to the contrary.
3. Registration of Transfers. Subject to
compliance with all applicable securities laws, the Company shall, or will cause its Transfer Agent to, register the transfer of all or
any portion of this Warrant in the Warrant Register, upon surrender of this Warrant, and payment for all applicable transfer taxes (if
any). Upon any such registration or transfer, a new warrant to purchase Common Stock in substantially the form of this Warrant (any such
new warrant, a “New Warrant”) evidencing the portion of this Warrant so transferred shall be issued to the transferee,
and a New Warrant evidencing the remaining portion of this Warrant not so transferred, if any, shall be issued to the transferring Holder.
The acceptance of the New Warrant by the transferee thereof shall be deemed the acceptance by such transferee of all of the rights and
obligations in respect of the New Warrant that the Holder has in respect of this Warrant. The Company shall, or will cause its Transfer
Agent to, prepare, issue and deliver at the Company’s own expense any New Warrant under this Section 3. Until due presentment
for registration of transfer, the Company may treat the registered Holder hereof as the owner and holder for all purposes, and the Company
shall not be affected by any notice to the contrary.
4. Exercise and Duration of Warrants.
(a) All or any part of this Warrant shall
be exercisable by the registered Holder in any manner permitted by this Warrant (including Section 11) at any time and from time
to time on or after the Initial Exercise Date and on or before the Termination Date.
(b) The Holder may exercise this Warrant
by delivering to the Company (i) an exercise notice, in the form attached as Schedule 1 hereto (the “Exercise Notice”),
completed and duly signed, of the Holder’s election to exercise this Warrant for, at the Holder’s sole discretion, either
(A) Warrant Shares or (B) Pre-Funded Warrants to purchase a number of shares of Common Stock equal to the number of Warrant
Shares as to which this Warrant is being exercised in substantially the same form of Pre-Funded Warrant included in the Company’s
Current Report on Form 8-K filed with the Securities and Exchange Commission on May [18], 2026 (“Pre-Funded Warrants”)
with an exercise price of $0.01 per share of Common Stock and (ii) payment of the Exercise Price for the number of Warrant Shares
as to which this Warrant is being exercised (which may take the form of a “cashless exercise” if permitted by Section 10
below and so indicated in the Exercise Notice pursuant to Section 10 below), or, if this Warrant is being exercised for Pre-Funded
Warrants, the aggregate Exercise Price, less $0.01, multiplied by the number of Warrant Shares as to which this Warrant is being exercised.
The date on which Exercise Notice is delivered to the Company (as determined in accordance with the notice provisions hereof) is an “Exercise
Date.” The Holder shall not be required to deliver the original Warrant in order to effect an exercise hereunder. Execution
and delivery of the Exercise Notice shall have the same effect as cancellation of the original Warrant and issuance of a New Warrant evidencing
the right to purchase the remaining number of Warrant Shares, if any. The Holder and any assignee, by acceptance of this Warrant, acknowledge
and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the Warrant Shares and Pre-Funded
Warrants hereunder, the number of Warrant Shares and Pre-Funded Warrants available for purchase hereunder at any given time may be less
than the amount stated on the face hereof.
5. Delivery of Warrant Shares.
(a) If this Warrant is being exercised for
Warrant Shares, upon exercise of this Warrant, the Company shall, or shall cause the Transfer Agent to, promptly (but in no event later
than the number of Trading Days comprising the Standard Settlement Period following the Exercise Date), upon the request of the Holder,
credit such aggregate number of shares of Common Stock to which the Holder is entitled pursuant to such exercise to the Holder’s
or its designee’s balance account with The Depository Trust Company (“DTC”) through its Deposit Withdrawal Agent
Commission system, or if the Transfer Agent is not participating in the Fast Automated Securities Transfer Program or if the certificates
are required to bear a legend regarding restriction on transferability, issue and dispatch by overnight courier to the address as specified
in the Exercise Notice, a certificate, registered in the Company’s share register in the name of the Holder or its designee, for
the number of shares of Common Stock to which the Holder is entitled pursuant to such exercise. If this Warrant is being exercised for
Pre-Funded Warrants, the Company shall issue and dispatch by overnight courier to the address specified in the Exercise Notice, Pre-Funded
Warrants to purchase a number of shares of Common Stock equal to the number of Warrant Shares with respect to which this Warrant is being
exercised. The Holder, or any natural person or legal entity (each, a “Person”) so designated by the Holder to receive
Warrant Shares or Pre-Funded Warrants, shall be deemed to have become the holder of record of such Warrant Shares or Pre-Funded Warrants
as of the Exercise Date, irrespective of the date such Warrant Shares are credited to the Holder’s DTC account or the date of delivery
of the certificates evidencing such Warrant Shares or Pre-Funded Warrants, as the case may be.
(b) If this Warrant is being exercised for
Warrant Shares, if the Company fails to deliver to the Holder a certificate representing the required number of Warrant Shares in the
manner required pursuant to Section 5(a) or fails to credit, or cause the Transfer Agent to credit, the Holder’s
DTC account for such number of Warrant Shares to which the Holder is entitled within the Standard Settlement Period following the Exercise
Date, and if after such Standard Settlement Period and prior to the receipt of such Warrant Shares, the Holder purchases (in an open market
transaction or otherwise) shares of Common Stock to deliver in satisfaction of a sale by the Holder of the Warrant Shares which the Holder
anticipated receiving upon such exercise (a “Buy-In”), then the Company shall, within one (1) Trading Day after
the Holder’s request promptly honor its obligation to deliver to the Holder a certificate or certificates representing such Warrant
Shares and pay cash to the Holder in an amount equal to the excess (if any) of Holder’s total purchase price (including brokerage
commissions, if any) for the shares of Common Stock so purchased in the Buy-In less the product of (A) the number of shares of Common
Stock purchased in the Buy-In, times (B) the Closing Sale Price of a share of Common Stock on the Exercise Date.
(c) To the extent permitted by law and subject
to Section 5(b), the Company’s obligations to issue and deliver Warrant Shares or Pre-Funded Warrants, as the case may be,
in accordance with and subject to the terms hereof (including the limitations set forth in Section 11 below) are absolute and unconditional,
irrespective of any action or inaction by the Holder to enforce the same, any waiver or consent with respect to any provision hereof,
the recovery of any judgment against any Person or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation
or termination, or any breach or alleged breach by the Holder or any other Person of any obligation to the Company or any violation or
alleged violation of law by the Holder or any other Person, and irrespective of any other circumstance that might otherwise limit such
obligation of the Company to the Holder in connection with the issuance of Warrant Shares or Pre-Funded Warrants. Subject to Section 5(b),
nothing herein shall limit the Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including,
without limitation, a decree of specific performance and/or injunctive relief with respect to the Company’s failure to timely deliver
shares of Common Stock or Pre-Funded Warrants upon exercise of the Warrant as required pursuant to the terms hereof.
6. Charges, Taxes and Expenses. Issuance
and delivery of shares of Common Stock upon exercise of this Warrant shall be made without charge to the Holder for any issue or transfer
tax, transfer agent fee or other incidental tax or expense (excluding any applicable stamp duties) in respect of the issuance of such
shares, all of which taxes and expenses shall be paid by the Company; provided, however, that the Company shall not be required
to pay any tax that may be payable in respect of any transfer involved in the registration of any Warrant Shares or the Warrants in a
name other than that of the Holder or an Affiliate thereof. The Holder shall be responsible for all other tax liability that may arise
as a result of holding or transferring this Warrant or receiving Warrant Shares upon exercise hereof.
7. Replacement of Warrant. If this Warrant
is mutilated, lost, stolen or destroyed, the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation
hereof, or in lieu of and substitution for this Warrant, a New Warrant, but only upon receipt of evidence reasonably satisfactory to the
Company of such loss, theft or destruction (in such case) and, in each case, a customary and reasonable contractual indemnity, if requested
by the Company. Applicants for a New Warrant under such circumstances shall also comply with such other reasonable regulations and procedures
and pay such other reasonable third-party costs as the Company may prescribe. If a New Warrant is requested as a result of a mutilation
of this Warrant, then the Holder shall deliver such mutilated Warrant to the Company as a condition precedent to the Company’s obligation
to issue the New Warrant.
8. Reservation of Warrant Shares. The Company
covenants that it will, at all times while this Warrant is outstanding, reserve and keep available out of the aggregate of its authorized
but unissued and otherwise unreserved Common Stock, solely for the purpose of enabling it to issue Warrant Shares upon exercise of this
Warrant as herein provided, the number of Warrant Shares that are initially issuable and deliverable upon the exercise of this entire
Warrant, free from preemptive rights or any other contingent purchase rights of persons other than the Holder (taking into account the
adjustments and restrictions of Section 9). The Company covenants that all Warrant Shares so issuable and deliverable shall, upon
issuance and the payment of the applicable Exercise Price in accordance with the terms hereof, be duly and validly authorized, issued
and fully paid and non-assessable. The Company will take all such action as may be reasonably necessary to assure that such shares of
Common Stock may be issued as provided herein without violation of any applicable law or regulation, or of any requirements of any securities
exchange or automated quotation system upon which the Common Stock may be listed. The Company further covenants that it will not, without
the prior written consent of the Holder, take any actions to increase the par value of the Common Stock at any time while this Warrant
is outstanding.
9. Certain Adjustments. The Exercise Price
and number of Warrant Shares issuable upon exercise of this Warrant (the “Number of Warrant Shares”) are subject to
adjustment from time to time as set forth in this Section 9.
(a) Stock Dividends and Splits. If
the Company, at any time while this Warrant is outstanding, (i) pays a stock dividend on its Common Stock or otherwise makes a distribution
on any class of capital stock that is payable in shares of Common Stock, (ii) subdivides its outstanding shares of Common Stock into
a larger number of shares of Common Stock, (iii) combines its outstanding shares of Common Stock into a smaller number of shares
of Common Stock or (iv) issues by reclassification of shares of capital stock any additional shares of Common Stock of the Company,
then in each such case the Number of Warrant Shares shall be multiplied by a fraction, the numerator of which shall be the number of shares
of Common Stock outstanding immediately after such event and the denominator of which shall be the number of shares of Common Stock outstanding
immediately before such event. Any adjustment made pursuant to clause (i) of this paragraph shall become effective immediately after
the record date for the determination of stockholders entitled to receive such dividend or distribution, provided, however, that if such
record date shall have been fixed and such dividend is not fully paid on the date fixed therefor, the Number of Warrant Shares shall be
recomputed accordingly as of the close of business on such record date and thereafter the Number of Warrant Shares shall be adjusted pursuant
to this paragraph as of the time of actual payment of such dividends. Any adjustment pursuant to clause (ii), (iii) or (iv) of
this paragraph shall become effective immediately after the effective date of such subdivision, combination or issuance.
(b) Pro Rata Distributions. During
such time as this Warrant is outstanding, if the Company shall declare or make any dividend or other distribution of its assets (or rights
to acquire its assets) to holders of shares of Common Stock, by way of return of capital or otherwise (including, without limitation,
any distribution of cash, stock or other securities, property or options by way of a dividend, spin off, reclassification, corporate rearrangement,
scheme of arrangement or other similar transaction) (a “Distribution”), at any time after the issuance of this
Warrant, then, in each such case, the Holder shall be entitled to participate in such Distribution to the same extent that the Holder
would have participated therein if the Holder had held the number of shares of Common Stock acquirable upon complete exercise of this
Warrant (without regard to any limitations on exercise hereof, including without limitation, the Beneficial Ownership Limitation) immediately
before the date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders
of shares of Common Stock are to be determined for the participation in such Distribution (provided, however, that to the
extent that the Holder’s right to participate in any such Distribution would result in the Holder exceeding the Beneficial Ownership
Limitation, then the Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership of
any shares of Common Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance
for the benefit of the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership
Limitation).
(c) Fundamental Transactions. If,
at any time while this Warrant is outstanding (i) the Company effects any merger or consolidation of the Company with or into another
Person, in which the Company is not the surviving entity or in which the stockholders of the Company immediately prior to such merger
or consolidation do not own, directly or indirectly, at least 50% of the voting power of the surviving entity immediately after such merger
or consolidation, (ii) the Company effects any sale, transfer or disposition to another Person of all or substantially all of its
assets in one transaction or a series of related transactions, (iii) pursuant to any tender offer or exchange offer (whether by the
Company or another Person), holders of capital stock tender shares representing more than 50% of the voting power of the capital stock
of the Company and the Company or such other Person, as applicable, accepts such tender for payment, (iv) the Company consummates
a stock purchase agreement or other business combination (including, without limitation, a reorganization, recapitalization, spin-off
or scheme of arrangement) with another Person whereby such other Person acquires more than the 50% of the voting power of the capital
stock of the Company (except for any such transaction in which the stockholders of the Company immediately prior to such transaction maintain,
in substantially the same proportions, the voting power of such Person immediately after the transaction) or (v) the Company effects
any reclassification of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively converted
into or exchanged for other securities, cash or property (other than as a result of a subdivision or combination of shares of Common Stock
covered by Section 9(a) above) (in any such case, a “Fundamental Transaction”), then following such Fundamental
Transaction the Holder shall have the right to receive, upon exercise of this Warrant, the same amount and kind of securities, cash or
property as it would have been entitled to receive upon the occurrence of such Fundamental Transaction if it had been, immediately prior
to such Fundamental Transaction, the holder of the Number of Warrant Shares without regard to any limitations on exercise contained herein
(in the case of clause (iii) above, assuming it had tendered, and the offeror had accepted, such Warrant Shares) (the “Alternate
Consideration”). The Company shall not effect any Fundamental Transaction in which the Company is not the surviving entity or
the Alternate Consideration includes securities of another Person unless (i) the Alternate Consideration is solely cash and the Company
provides for the simultaneous “cashless exercise” of this Warrant pursuant to Section 10 below or (ii) prior to
or simultaneously with the consummation thereof, any successor to the Company, surviving entity or other Person (including any purchaser
of assets of the Company) shall assume the obligation to deliver to the Holder such Alternate Consideration as, in accordance with the
foregoing provisions, the Holder may be entitled to receive, and the other obligations under this Warrant. The provisions of this paragraph
(c) shall similarly apply to subsequent transactions analogous of a Fundamental Transaction type. Notwithstanding anything to the
contrary, in the event of a Fundamental Transaction (other than (x) any stock split or reverse stock split, (y) any transaction
effected solely for the purpose of changing the jurisdiction of incorporation of the Company, or (z) any holding company reorganization
or parent-subsidiary merger not requiring stockholder approval pursuant to Sections 251(g) or 253 of the General Corporation Law
of the State of Delaware (or any successor provisions thereof)), the Company or any Successor Entity (as defined below) shall, at the
Holder’s option, exercisable at any time concurrently with, or within 30 days after, the consummation of the Fundamental Transaction
(or, if later, the date of the public announcement of the applicable Fundamental Transaction), purchase this Warrant from the Holder by
paying to the Holder an amount of cash equal to the Black Scholes Value (as defined below) of the remaining unexercised portion of this
Warrant on the date of the consummation of such Fundamental Transaction; provided, however, that, if the Fundamental Transaction is not
within the Company’s control, including not approved by the Company’s Board of Directors, the Holder shall only be entitled
to receive from the Company or any Successor Entity as of the date of the consummation of such Fundamental Transaction the same type or
form of consideration (and in the same proportion), valued at the Black Scholes Value of the unexercised portion of this Warrant, that
is being offered and paid to the holders of Common Stock of the Company in connection with the Fundamental Transaction, whether that consideration
be in the form of cash, stock or any combination thereof, or whether the holders of Common Stock are given the choice to receive from
among alternative forms of consideration in connection with the Fundamental Transaction; provided, further, that if holders of Common
Stock of the Company are not offered or paid any consideration in such Fundamental Transaction, such cash payment right shall not apply.
“Black Scholes Value” means the value of this Warrant based on the Black-Scholes Option Pricing Model obtained from the “OV”
function on Bloomberg determined as of the day of consummation of the applicable Fundamental Transaction for pricing purposes and reflecting
(A) a risk-free interest rate corresponding to the U.S. Treasury rate for a period equal to the time between the date of the public
announcement of the applicable contemplated Fundamental Transaction and the Termination Date, (B) an expected volatility equal to
the lesser of 100% and the 100 day volatility as obtained from the HVT function on Bloomberg (determined utilizing a 365-day annualization
factor) as of the Trading Day immediately following the public announcement of the applicable contemplated Fundamental Transaction, (C) the
underlying price per share used in such calculation shall be the greater of (i) the sum of the price per share being offered in cash,
if any, plus the value of any non-cash consideration, if any, being offered in such Fundamental Transaction and (ii) the VWAP immediately
preceding the public announcement of the applicable contemplated Fundamental Transaction (or the consummation of the applicable Fundamental
Transaction, if earlier), (D) a remaining option time equal to the time between the date of the public announcement of the applicable
contemplated Fundamental Transaction and the Termination Date, and (E) a zero cost of borrow. The payment of the Black Scholes Value
will be made by wire transfer of immediately available funds (or such other consideration) within the later of (i) five Business
Days of the Holder’s election and (ii) the date of consummation of the Fundamental Transaction. The Company shall cause any
successor entity in a Fundamental Transaction in which the Company is not the survivor (the “Successor Entity”) to
assume in writing all of the obligations of the Company under this Warrant in accordance with the provisions of this Section 9(c) pursuant
to written agreements in form and substance reasonably satisfactory to the Holder and approved by the Holder (without unreasonable delay)
prior to such Fundamental Transaction and shall, at the option of the Holder, deliver to the Holder in exchange for this Warrant a security
of the Successor Entity evidenced by a written instrument substantially similar in form and substance to this Warrant which is exercisable
for a corresponding number of shares of capital stock of such Successor Entity (or its parent entity) equivalent to the shares of Common
Stock acquirable and receivable upon exercise of this Warrant (without regard to any limitations on the exercise of this Warrant) prior
to such Fundamental Transaction, and with an exercise price which applies the exercise price hereunder to such shares of capital stock
(but taking into account the relative value of the shares of Common Stock pursuant to such Fundamental Transaction and the value of such
shares of capital stock, such adjustments to the number of shares of capital stock and such exercise price being for the purpose of protecting
the economic value of this Warrant immediately prior to the consummation of such Fundamental Transaction), and which is reasonably satisfactory
in form and substance to the Holder. Upon the occurrence of any such Fundamental Transaction, the Successor Entity shall succeed to, and
be substituted for the Company (so that from and after the date of such Fundamental Transaction, the provisions of this Warrant referring
to the “Company” shall refer instead to the Successor Entity), and may exercise every right and power of the Company and shall
assume all of the obligations of the Company under this Warrant with the same effect as if such Successor Entity had been named as the
Company herein. Notwithstanding the foregoing, and without limiting Section 11 hereof, the Holder may elect, at its sole option,
by delivery of written notice to the Company to waive this Section 9(c) to permit a Fundamental Transaction without the
assumption of this Warrant.
(d) Exercise Price. Simultaneously
with any adjustment to the Number of Warrant Shares pursuant to Section 9 the Exercise Price shall be increased or decreased proportionately,
so that after such adjustment the aggregate Exercise Price payable hereunder for the increased or decreased Number of Warrant Shares shall
be the same as the aggregate Exercise Price in effect immediately prior to such adjustment. Notwithstanding the foregoing, in no event
may the Exercise Price be adjusted below the par value of the Common Stock then in effect.
(e) Calculations. All calculations
under this Section 9 shall be made to the nearest one-hundredth of one cent or the nearest whole share, as applicable.
(f) Notice of Adjustments. Upon
the occurrence of each adjustment pursuant to this Section 9, the Company at its expense will promptly compute such adjustment,
in good faith, in accordance with the terms of this Warrant and prepare a certificate setting forth such adjustment, including a statement
of the adjusted Exercise Price and adjusted number or type of Warrant Shares or other securities issuable upon exercise of this Warrant
(as applicable), describing the transactions giving rise to such adjustments and showing in detail the facts upon which such adjustment
is based. Upon written request, the Company will promptly deliver a copy of each such certificate to the Holder and to the Transfer Agent.
(g) Notice of Corporate Events. If,
while this Warrant is outstanding, the Company (i) declares a dividend or any other distribution of cash, securities or other property
in respect of its Common Stock, including, without limitation, any granting of rights or warrants to subscribe for or purchase any capital
stock of the Company or any subsidiary, (ii) authorizes or approves, enters into any agreement contemplating or solicits stockholder
approval for any Fundamental Transaction or (iii) authorizes the voluntary dissolution, liquidation or winding up of the affairs
of the Company, then, except if such notice and the contents thereof shall be deemed to constitute material non-public information, the
Company shall deliver to the Holder a notice of such transaction at least ten (10) days prior to the applicable record or effective
date on which a Person would need to hold Common Stock in order to participate in or vote with respect to such transaction; provided,
however, that the failure to deliver such notice or any defect therein shall not affect the validity of the corporate action required
to be described in such notice. In addition, if while this Warrant is outstanding, the Company authorizes or approves, enters into any
agreement contemplating or solicits stockholder approval for any Fundamental Transaction contemplated by Section 9(c), other than
a Fundamental Transaction under clause (iii) of Section 9(c), then, except if such notice and the contents thereof shall be
deemed to constitute material non-public information, the Company shall deliver to the Holder a notice of such Fundamental Transaction
at least ten (10) days prior to the date such Fundamental Transaction is consummated.
(h) Voluntary Adjustment By Company.
Subject to the rules and regulations of the Principal Trading Market, the Company may at any time during the term of this Warrant,
reduce the then-current Exercise Price to any amount and for any period of time deemed appropriate by the board of directors of the Company.
10. Cashless Exercise. If at any time during
the term of this Warrant the Registration Statement or another registration statement registering the issuance of Warrant Shares is, for
any reason, not effective at the time of exercise of this Warrant, this Warrant may be exercised through a “cashless exercise.”
Upon exercise, the Company shall issue to the Holder the number of Warrant Shares in an exchange of securities effected pursuant to Section 3(a)(9) of
the Securities Act as determined as follows:
X = Y [(A-B)/A]
where:
“X” equals the number of Warrant Shares to be issued to
the Holder;
“Y” equals the total number of Warrant Shares with respect
to which this Warrant is then being exercised;
“A” equals the Closing Sale Price per share of Common Stock
as of the Trading Day on the date immediately preceding the Exercise Date; and
“B” equals the Exercise Price per Warrant Share then in
effect on the Exercise Date.
For purposes of Rule 144 promulgated under
the Securities Act, it is intended, understood and acknowledged that the Warrant Shares issued in such a “cashless exercise”
transaction shall be deemed to have been acquired by the Holder, and the holding period for the Warrant Shares shall be deemed to have
commenced, on the Original Issue Date (provided that the Commission continues to take the position that such treatment is proper at the
time of such exercise). In the event that the Registration Statement or another registration statement registering the issuance of Warrant
Shares is, for any reason, not effective at the time of exercise of this Warrant, then this Warrant may only be exercised through a cashless
exercise, as set forth in this Section 10.
Except as otherwise set forth herein, in no event
will the exercise of this Warrant be settled in cash.
11. Limitations on Exercise.
(a) Notwithstanding anything to the contrary
contained herein, the Company shall not effect any exercise of this Warrant (other than for Pre-Funded Warrants), and the Holder shall
not be entitled to exercise this Warrant (other than for Pre-Funded Warrants) (i) if immediately prior to the exercise, the Holder,
its Affiliates and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes
of Section 13(d) of the Exchange Act, beneficially own an aggregate number of shares of Common Stock greater than [4.5] [4.99]
[9.99] % (the “Maximum Percentage”) of the total number of issued and outstanding shares of Common Stock of the Company
without taking into account any Warrant Shares, or (ii) to the extent that immediately following the exercise, the Holder, its Affiliates
and any other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for purposes of Section 13(d) of
the Exchange Act, would beneficially own in excess of the Maximum Percentage of the number of shares of Common Stock outstanding immediately
after giving effect to the issuance of such shares of Common Stock. Any portion of an exercise that would result in the issuance of shares
in excess of the Maximum Percentage shall be treated as null and void ab initio. For purposes of this Warrant, in determining the number
of outstanding shares of Common Stock, the Holder may rely on the number of outstanding shares of Common Stock as reflected in (x) the
Company’s most recent Form 10-Q or Form 10-K, as the case may be, filed with the Commission prior to the Exercise Date,
(y) a more recent public announcement by the Company or (z) any other notice by the Company or its Transfer Agent setting forth
the number of shares of Common Stock outstanding. Upon the written request of the Holder, the Company shall within three (3) Trading
Days confirm in writing or by electronic mail to the Holder the number of shares of Common Stock then outstanding. In any case, the number
of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company,
including this Warrant, by the Holder since the date as of which such number of outstanding shares of Common Stock was reported. By written
notice to the Company, the Holder may from time to time increase or decrease the Maximum Percentage to any other percentage specified
not in excess of 19.99% specified in such notice; provided that any such increase will not be effective until the sixty-first (61st) day
after such notice is delivered to the Company. For purposes of this Section 11(a), the aggregate number of shares of Common Stock
or voting securities beneficially owned by the Holder and its Affiliates and any other Persons whose beneficial ownership of Common Stock
would be aggregated with the Holder’s for purposes of Section 13(d) of the Exchange Act shall include the shares of Common
Stock issuable upon the exercise of this Warrant with respect to which such determination is being made, but shall exclude the number
of shares of Common Stock which would be issuable upon (x) exercise of the remaining unexercised and non-cancelled portion of this
Warrant by the Holder and (y) exercise or conversion of the unexercised, non-converted or non-cancelled portion of any other securities
of the Company that do not have voting power (including without limitation any securities of the Company which would entitle the holder
thereof to acquire at any time Common Stock, including without limitation any debt, preferred stock, right, option, warrant or other instrument
that is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock),
is subject to a limitation on conversion or exercise analogous to the limitation contained herein and is beneficially owned by the Holder
or any of its Affiliates and other Persons whose beneficial ownership of Common Stock would be aggregated with the Holder’s for
purposes of Section 13(d) of the Exchange Act. For purposes of clarity, the Warrant Shares issuable pursuant to the terms of
this Warrant in excess of the Maximum Percentage shall not be deemed to be beneficially owned by the Holder for any purpose including
for purposes of Section 13(d) of the Exchange Act or Rule 16a-1(a)(1) promulgated under the Exchange Act.
(b) This Section 11 shall not restrict
the number of shares of Common Stock which a Holder may receive or beneficially own in order to determine the amount of securities or
other consideration that such Holder may receive in the event of a Fundamental Transaction as contemplated in Section 9(c) of
this Warrant.
12. No Fractional Shares or Pre-Funded Warrants.
No fractional Warrant Shares or fractional Pre-Funded Warrants will be issued in connection with any exercise of this Warrant. In lieu
of any fractional shares that would otherwise be issuable, the number of Warrant Shares to be issued shall be rounded down to the next
whole number and the Company shall pay the Holder in cash the fair market value (based on the Closing Sale Price) for any such fractional
shares.
13. Notices. Any and all notices or other
communications or deliveries hereunder (including, without limitation, any Exercise Notice) shall be in writing and shall be deemed given
and effective on the earliest of (i) the date of transmission, if such notice or communication is delivered via confirmed email prior
to 5:30 P.M., New York City time, on a Trading Day, (ii) the next Trading Day after the date of transmission, if such notice or communication
is delivered via confirmed e-mail on a day that is not a Trading Day or later than 5:30 P.M., New York City time, on any Trading Day,
(iii) the Trading Day following the date of mailing, if sent by nationally recognized overnight courier service specifying next business
day delivery, or (iv) upon actual receipt by the Person to whom such notice is required to be given, if by hand delivery. The addresses
and e-mail addresses for such communications shall be:
If to the Company:
Rapid Micro Biosystems, Inc.
25 Hartwell Avenue
Lexington, MA 02421
Attention: Chief Executive Officer
Telephone: (978) 349-3200
Email: [___]
If to the Holder, to its address or e-mail address set forth herein
or on the books and records of the Company.
Or, in each of the above instances, to such other
address or e-mail address as the recipient party has specified by written notice given to each other party at least five (5) days
prior to the effectiveness of such change.
14. Warrant Agent. The Company shall initially
serve as warrant agent under this Warrant. Upon ten (10) days’ notice to the Holder, the Company may appoint a new warrant
agent. Any corporation into which the Company or any new warrant agent may be merged or any corporation resulting from any consolidation
to which the Company or any new warrant agent shall be a party or any corporation to which the Company or any new warrant agent transfers
substantially all of its corporate trust or shareholders services business shall be a successor warrant agent under this Warrant without
any further act. Any such successor warrant agent shall promptly cause notice of its succession as warrant agent to be mailed (by first
class mail, postage prepaid) to the Holder at the Holder’s last address as shown on the Warrant Register.
15. Participation in Future Financing.
(a) From the date hereof until the date that
is the twelve (12) month anniversary of the Original Issue Date, upon any issuance by the Company of Common Stock or Common Stock
Equivalents for cash consideration (a “Subsequent Financing”), the Holder shall have the right to participate up to
an amount equal to its Pro Rata Portion of the Participation Maximum on the same terms, conditions and price provided for in the Subsequent
Financing.
(b) Between the time period of 4:00 pm (New
York City time) and 6:00 pm (New York City time) on the Trading Day immediately prior to the Trading Day of the expected announcement
of the Subsequent Financing (or, if the Trading Day of the expected announcement of the Subsequent Financing is the first Trading Day
following a holiday or a weekend (including a holiday weekend), between the time period of 4:00 pm (New York City time) on the Trading
Day immediately prior to such holiday or weekend and 2:00 pm (New York City time) on the day immediately prior to the Trading Day of the
expected announcement of the Subsequent Financing), the Company shall deliver to the Holder a written notice of the Company’s intention
to effect a Subsequent Financing (a “Subsequent Financing Notice”), which notice shall describe in reasonable detail
the proposed terms of such Subsequent Financing, the amount of proceeds intended to be raised thereunder and the Person or Persons through
or with whom such Subsequent Financing is proposed to be effected and shall include a term sheet and transaction documents relating thereto
as an attachment.
(c) If the Holder desires to participate
in such Subsequent Financing, the Holder must provide written notice to the Company by 6:30 am (New York City time) on the Trading Day
following the date on which the Subsequent Financing Notice is delivered to the Holder (the “Notice Termination Time”)
that the Holder is willing to participate in the Subsequent Financing, the amount of the Holder’s participation, and representing
and warranting that the Holder has such funds ready, willing, and available for investment on the terms set forth in the Subsequent Financing
Notice. If the Company receives no such notice from the Holder as of such Notice Termination Time, the Holder shall be deemed to have
notified the Company that it does not elect to participate in such Subsequent Financing.
(d) If, by the Notice Termination Time, notifications
by the Holder of their willingness to participate in the Subsequent Financing (or to cause their designees to participate) is, in the
aggregate, less than the total amount of the Participation Maximum, then the Company may effect the remaining portion of such Participation
Maximum on the terms and with the Persons set forth in the Subsequent Financing Notice.
(e) Notwithstanding anything to the contrary
pursuant to the Holder’s rights to its Pro Rata Portion pursuant to this Section 15, if the number of shares of Common Stock
issuable to the Holder pursuant to any proposed Subsequent Financing, when aggregated with all other shares of Common Stock beneficially
owned by the Holder (and its Affiliates) at such time of such Subsequent Financing, would result in the Holder (and its Affiliates) beneficially
owning the Maximum Percentage then in lieu of receiving shares of Common Stock in a Subsequent Financing that would result in the Holder
(and its Affiliates) exceeding the Maximum Percentage, the Holder shall receive Common Stock Equivalents (such as pre-funded Common
Stock purchase warrants) with a beneficial ownership blocker in the form of Section 11 hereof, in order for the Holder (and its Affiliates)
to maintain a beneficial ownership at or below the Maximum Percentage
(f) Notwithstanding the foregoing, this Section 15
shall not apply in respect of (i) an Exempt Issuance and (ii) entry into and/or issuance of shares of Common Stock in an “at
the market” offering.
(g) The rights of the Holder pursuant to
this Section 15 are personal to the original Holder and shall not be transferable or assignable to any transferee or assignee of
this Warrant or otherwise, without the prior written consent of the Company. Any purported transfer or assignment of such rights in violation
of this Section 15 shall be null and void ab initio.
(h) The Holder agrees that any Subsequent
Financing Notice and any Subsequent Financing Information (as defined below) received by the Holder may constitute material non-public
information of the Company and the Holder shall treat any Subsequent Financing Notice and any information contained therein or otherwise
received by the Holder in connection with a Subsequent Financing (collectively, “Subsequent Financing Information”)
as confidential information of the Company and as potential material non-public information and shall not disclose any Subsequent Financing
Information to any person other than the Holder's officers, directors, employees, advisors and representatives who have a need to know
such information in connection with the Holder's evaluation of its participation in such Subsequent Financing and who are bound by obligations
of confidentiality no less restrictive than those set forth herein and who have been informed of the potential material non-public information
status of such Subsequent Financing Information; provided, however, that the foregoing confidentiality obligations shall not apply to
any Subsequent Financing Information that (i) is or becomes publicly available other than as a result of a disclosure by the Holder
in breach of this Section 15(h), (ii) was known to the Holder on a non-confidential basis prior to its receipt from the Company,
or (iii) becomes available to the Holder on a non-confidential basis from a source other than the Company that is not, to the Holder's
knowledge, subject to any obligation of confidentiality with respect thereto. The Holder agrees that (i) applicable securities laws
prohibit any person who has material, non-public information concerning the Company or any of its Affiliates from trading in the securities
of the Company while in possession of such information, or from communicating such information to any other person or entity under circumstances
in which it is reasonably foreseeable that such person is likely to trade such securities.
16. Miscellaneous.
(a) No Rights as a Stockholder. Except
as otherwise set forth in this Warrant, the Holder, solely in such Person’s capacity as a holder of this Warrant, shall not be entitled
to vote or receive dividends or be deemed the holder of share capital of the Company for any purpose, nor shall anything contained in
this Warrant be construed to confer upon the Holder, solely in such Person’s capacity as the Holder of this Warrant, any of the
rights of a stockholder of the Company or any right to vote, give or withhold consent to any corporate action (whether any reorganization,
issue of stock, reclassification of stock, consolidation, merger, amalgamation, conveyance or otherwise), receive notice of meetings,
receive dividends or subscription rights, or otherwise, prior to the issuance to the Holder of the Warrant Shares which such Person is
then entitled to receive upon the due exercise of this Warrant. In addition, nothing contained in this Warrant shall be construed as imposing
any liabilities on the Holder to purchase any securities (upon exercise of this Warrant or otherwise) or as a stockholder of the Company,
whether such liabilities are asserted by the Company or by creditors of the Company.
(b) Authorized Shares; Further Assurances.
Except and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation,
amending its certificate or articles of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution,
issue or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of
this Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as
may be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the
generality of the foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor
upon such exercise immediately prior to such increase in par value, (ii) take all such action as may be necessary or appropriate
in order that the Company may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant,
and (iii) use commercially reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory
body having jurisdiction thereof as may be necessary to enable the Company to perform its obligations under this Warrant. Before taking
any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the Exercise
Price, the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from any public
regulatory body or bodies having jurisdiction thereof.
(c) Successors and Assigns. Subject
to compliance with applicable securities laws, this Warrant may be assigned by the Holder; provided that the participation right under
Section 15 hereof may not be transferred to more than one transferee. This Warrant may not be assigned by the Company without the
written consent of the Holder, except to a successor in the event of a Fundamental Transaction. This Warrant shall be binding on and inure
to the benefit of the Company and the Holder and their respective successors and assigns. Subject to the preceding sentence, nothing in
this Warrant shall be construed to give to any Person other than the Company and the Holder any legal or equitable right, remedy or cause
of action under this Warrant. This Warrant may be amended only in writing signed by the Company and the Holder, or their successors and
assigns.
(d) Amendment and Waiver. Except as
otherwise provided herein, this Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company
and the Holder; provided that, Section 11(a) may not be modified or amended.
(e) Acceptance. Receipt of this Warrant
by the Holder shall constitute acceptance of and agreement to all of the terms and conditions contained herein.
(f) Governing Law; Jurisdiction.
ALL QUESTIONS CONCERNING THE CONSTRUCTION, VALIDITY, ENFORCEMENT AND INTERPRETATION OF THIS WARRANT SHALL BE GOVERNED BY AND CONSTRUED
AND ENFORCED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK WITHOUT REGARD TO THE PRINCIPLES OF CONFLICTS OF LAW THEREOF. EACH
OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY SUBMITS TO THE EXCLUSIVE JURISDICTION OF THE STATE AND FEDERAL COURTS SITTING IN THE
CITY OF NEW YORK, BOROUGH OF MANHATTAN, FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION HEREWITH OR WITH ANY TRANSACTION
CONTEMPLATED HEREBY OR DISCUSSED HEREIN (INCLUDING WITH RESPECT TO THE ENFORCEMENT OF ANY OF THE TRANSACTION DOCUMENTS), AND HEREBY IRREVOCABLY
WAIVES, AND AGREES NOT TO ASSERT IN ANY SUIT, ACTION OR PROCEEDING, ANY CLAIM THAT IT IS NOT PERSONALLY SUBJECT TO THE JURISDICTION OF
ANY SUCH COURT. EACH OF THE COMPANY AND THE HOLDER HEREBY IRREVOCABLY WAIVES PERSONAL SERVICE OF PROCESS AND CONSENTS TO PROCESS BEING
SERVED IN ANY SUCH SUIT, ACTION OR PROCEEDING BY MAILING A COPY THEREOF VIA REGISTERED OR CERTIFIED MAIL OR OVERNIGHT DELIVERY (WITH
EVIDENCE OF DELIVERY) TO SUCH PERSON AT THE ADDRESS IN EFFECT FOR NOTICES TO IT AND AGREES THAT SUCH SERVICE SHALL CONSTITUTE GOOD AND
SUFFICIENT SERVICE OF PROCESS AND NOTICE THEREOF. NOTHING CONTAINED HEREIN SHALL BE DEEMED TO LIMIT IN ANY WAY ANY RIGHT TO SERVE PROCESS
IN ANY MANNER PERMITTED BY LAW. EACH OF THE COMPANY AND THE HOLDER HEREBY WAIVES ALL RIGHTS TO A TRIAL BY JURY.
(g) Headings. The headings herein
are for convenience only, do not constitute a part of this Warrant and shall not be deemed to limit or affect any of the provisions hereof.
(h) Severability. In case any one
or more of the provisions of this Warrant shall be invalid or unenforceable in any respect, the validity and enforceability of the remaining
terms and provisions of this Warrant shall not in any way be affected or impaired thereby, and the Company and the Holder will attempt
in good faith to agree upon a valid and enforceable provision which shall be a commercially reasonable substitute therefor, and upon so
agreeing, shall incorporate such substitute provision in this Warrant.
REMAINDER OF PAGE INTENTIONALLY LEFT BLANK.
IN WITNESS WHEREOF, the Company has caused this Warrant to be duly
executed by its authorized officer as of the date first indicated above.
RAPID MICRO BIOSYSTEMS, INC.
By:
Name:
Robert Spignesi
Title:
President and Chief Executive Officer
SCHEDULE 1
FORM OF EXERCISE NOTICE
[To be executed by the Holder to purchase shares
of Common Stock under the Warrant]
Ladies and Gentlemen: (1) The undersigned is the Holder of Warrant
No. ___ (the “Warrant”) issued by Rapid Micro Biosystems, Inc., a Delaware corporation (the “Company”).
Capitalized terms used herein and not otherwise defined herein have the respective meanings set forth in the Warrant.
(2)
The undersigned hereby exercises its right to purchase ___________ Warrant Shares and ___________ Pre-Funded Warrants pursuant to the Warrant.
(3)
The Holder intends that payment of the Exercise Price shall be made as (check one):
☐
Cash Exercise with respect to Warrant Shares
☐
“Cashless Exercise” under Section 10 of the Warrant with respect to Warrant Shares
☐
Cash Exercise with respect to Pre-Funded Warrants
☐
“Cashless Exercise” under Section 10 of the Warrant with respect to Pre-Funded Warrants
(4)
If the Holder has elected a Cash Exercise, the Holder shall pay the sum of $ _____ in immediately available funds to the Company in accordance with the terms of the Warrant.
(5)
Pursuant to this Exercise Notice, the Company shall deliver to the Holder Warrant Shares or Pre-Funded Warrants determined in accordance with the terms of the Warrant. The Warrant Shares shall be delivered to the following DWAC Account Number:
(6)
By its delivery of this Exercise Notice, the undersigned represents and warrants to the Company that in giving effect to the exercise evidenced hereby the Holder will not beneficially own in excess of the number of shares of Common Stock (as determined in accordance with Section 13(d) of the Securities Exchange Act of 1934, as amended) permitted to be owned under Section 11(a) of the Warrant to which this notice relates.
Dated:
Name of Holder:
By:
Name:
Title:
(Signature must conform in all respects to name of Holder as specified
on the face of the Warrant)
EX-5.1 — EXHIBIT 5.1
EX-5.1
Filename: tm2614922d1_ex5-1.htm · Sequence: 6
Exhibit 5.1
Goodwin LLP
100 Northern Avenue
Boston, MA 02210
goodwinlaw.com
+1 617 570 1000
May 19, 2026
Rapid Micro Biosystems, Inc.
25 Hartwell Avenue
Lexington, MA 02421
Re: Securities
Registered under Registration Statement on Form S-3
We have acted as counsel to you in connection with your filing of a
Registration Statement on Form S-3 (File No. 333-276081) (as amended or supplemented, the “Registration Statement”)
filed on December 15, 2023 with the Securities and Exchange Commission (the “Commission”) pursuant to the Securities
Act of 1933, as amended (the “Securities Act”), relating to the registration of the offer by Rapid Micro Biosystems, Inc.,
a Delaware corporation (the “Company”), of up to $200,000,000 of any combination of securities of the types specified therein.
The Registration Statement was declared effective by the Commission on December 26, 2023. Reference is made to our opinion letter
dated December 15, 2023 and included as Exhibit 5.1 to the Registration Statement. We are delivering this supplemental opinion
letter in connection with the prospectus supplement (the “Prospectus Supplement”) filed on May 19, 2026 by the Company
with the Commission pursuant to Rule 424 under the Securities Act. The Prospectus Supplement relates to the offering by the Company
of up to (i) 3,581,000 shares of the Company’s Class A common stock, par value $0.01 per share (the “Common Stock”),
(ii) pre-funded warrants (“Pre-Funded Warrants”) to purchase up to an aggregate of 1,463,000 shares of Common Stock (the
“Pre-Funded Warrant Shares”), (iii) warrants (the “Series A Common Warrants”) to purchase up to an aggregate
of 5,044,000 shares of Common Stock (the “Series A Common Warrant Shares”) or pre-funded warrants (the “Series A
Pre-Funded Warrants”) and (iv) warrants (the “Series B Common Warrants” and together with the Series A
Common Warrants, the “Common Warrants”, and, together with the Pre-Funded Warrants, the “Warrants”) to purchase
up to an aggregate of 5,044,000 shares of Common Stock (the “Series B Warrant Shares”) or pre-funded warrants (the “Series B
Pre-Funded Warrants” and together with the Series A Pre-Funded Warrants, the “Underlying Pre-Funded Warrants”).
The shares of Common Stock issuable from time to time upon exercise of the Pre-Funded Warrants, the Series A Common Warrants, the
Series B Common Warrants and the Underlying Pre-Funded Warrants are herein referred to collectively as the “Warrant Shares”
and together with the Common Stock, the “Shares”), covered by the Registration Statement. The Shares and Warrant Shares are
being sold to the several underwriters named in, and pursuant to, an underwriting agreement among the Company and such underwriters (the
“Underwriting Agreement”).
We have reviewed such documents and made such examination of law as
we have deemed appropriate to give the opinions set forth below. We have relied, without independent verification, on certificates of
public officials and, as to matters of fact material to the opinion set forth below, on certificates of officers of the Company. For purposes
of the opinion set forth in paragraph 3 below, we have assumed that before the Warrant Shares are issued, the Company does not issue shares
of Common Stock or reduce the total number of shares of Common Stock the Company is authorized to issue under its certificate of incorporation
such that the number of unissued shares of Common Stock authorized under the Company’s certificate of incorporation is less than
the number of Warrant Shares.
Rapid Micro Biosystems, Inc.
May 19, 2026
Page 2
The opinions set forth below are limited to the Delaware General Corporation
Law, and with respect to the opinion in paragraph 2, the law of the State of New York.
Based on the foregoing, we are of the opinion that:
1. The Shares have been duly authorized and, when delivered and paid for in accordance with the terms of the Underwriting Agreement will
be validly issued, fully paid and non-assessable.
2. The Warrants have been duly authorized and executed by the Company and, when delivered and paid for in accordance with the terms of
the Underwriting Agreement, will be valid and binding obligations of the Company enforceable against the Company in accordance with their
terms..
3. The Underlying Pre-Funded Warrants have been duly authorized by the Company for issuance upon exercise of the Series A
Common Warrants or the Series B Common Warrants, as applicable, in accordance with their terms, and, if issued today by the Company
and assuming due execution and delivery, against payment therefor upon exercise of the Series A Common Warrants of the Series B
Common Warrants, as applicable, would be valid and binding obligations of the Company, enforceable against the Company in accordance with
their terms.
4. Assuming sufficient authorized but unissued shares of Common Stock are available for issuance when the Warrants are exercised, the
Warrant Shares, when issued upon exercise of the Pre-Funded Warrants and/or Common Warrants in accordance with the terms of the Pre-Funded
Warrants and/or Common Warrants, will be validly issued, fully paid and non-assessable.
The opinions expressed above are subject to bankruptcy, insolvency,
fraudulent transfer, reorganization, moratorium and other similar laws of general application affecting the rights and remedies of creditors
and to general principles of equity.
This opinion letter and the opinions it contains shall be interpreted
in accordance with the Core Opinion Principles as published in 74 Business Lawyer 815 (Summer 2019).
We hereby consent to the inclusion of this opinion as Exhibit 5.1
to the Current Report on Form 8-K and to the references to our firm under the caption “Legal Matters” in the Registration
Statement. In giving our consent, we do not admit that we are in the category of persons whose consent is required under Section 7
of the Securities Act or the rules and regulations thereunder.
Very truly yours,
/s/ Goodwin Procter LLP
GOODWIN PROCTER LLP
EX-5.2 — EXHIBIT 5.2
EX-5.2
Filename: tm2614922d1_ex5-2.htm · Sequence: 7
Exhibit 5.2
Goodwin LLP
100 Northern Avenue
Boston, MA 02210
goodwinlaw.com
+1 617 570 1000
May 19, 2026
Rapid Micro Biosystems, Inc.
25 Hartwell Avenue
Lexington, MA 02421
Re: Securities Registered under Registration Statement on Form S-3
We have acted as counsel to you in connection with your filing of a
Registration Statement on Form S-3 (File No. 333-276081) (as amended or supplemented, the “Registration Statement”)
filed on December 15, 2023 with the Securities and Exchange Commission (the “Commission”) pursuant to the Securities
Act of 1933, as amended (the “Securities Act”), relating to the registration of the offer by Rapid Micro Biosystems, Inc.,
a Delaware corporation (the “Company”), of up to $200,000,000 of any combination of securities of the types specified therein.
The Registration Statement was declared effective by the Commission on December 26, 2023. Reference is made to our opinion letter
dated December 15, 2023 and included as Exhibit 5.1 to the Registration Statement.
We are delivering this supplemental opinion letter in connection with
the prospectus supplement (the “Prospectus Supplement”) filed on May 19, 2026 by the Company with the Commission pursuant
to Rule 424 under the Securities Act. The Prospectus Supplement relates to the offering by the Company of up to (i) 71,607 shares
(the “Common Shares”) of the Company’s Class A common stock, par value $0.01 per share (the “Common Stock”),
(ii) warrants (the “Series A Warrants”) to purchase up to an aggregate of 71,607 shares of Common Stock (the “Series A
Common Warrant Shares”) or pre-funded warrants (the “Series A Pre-Funded Warrants”) and (iii) warrants (the
“Series B Warrants” and together with the Series A Warrants, the “Warrants”) to purchase up to an aggregate
of 71,607 shares of Common Stock or pre-funded warrants (the “Series B Pre-Funded Warrants” and together with the Series A
Pre-Funded Warrants, the “Underlying Pre-Funded Warrants”). The shares of Common Stock issuable from time to time upon exercise
of the Series A Warrants, the Series B Warrants and the Underlying Pre-Funded Warrants are herein referred to collectively as
the “Warrant Shares” and together with the Common Shares, the “Shares”). The Common Shares and Warrants are being
sold directly to certain directors and officers of the Company, pursuant to a securities purchase agreement, dated May 18, 2026,
by and between the Company and certain directors and officers (the “Purchase Agreement”).
We have reviewed such documents and made such examination of law as
we have deemed appropriate to give the opinions set forth below. We have relied, without independent verification, on certificates of
public officials and, as to matters of fact material to the opinion set forth below, on certificates of officers of the Company. For purposes
of the opinion set forth in paragraph 3 below, we have assumed that before the Warrant Shares are issued, the Company does not issue shares
of Common Stock or reduce the total number of shares of Common Stock the Company is authorized to issue under its certificate of incorporation
such that the number of unissued shares of Common Stock authorized under the Company’s certificate of incorporation is less than
the number of Warrant Shares.
Rapid Micro Biosystems, Inc.
May 19, 2026
Page 2
The opinions set forth below are limited to the Delaware General Corporation
Law, and with respect to the opinion in paragraph 2, the law of the State of New York.
Based on the foregoing, we are of the opinion that:
1. The Common Shares have been duly authorized and, when delivered and paid for in accordance with the terms of the Purchase Agreement,
will be validly issued, fully paid and non-assessable.
2. The Warrants have been duly authorized and executed by the Company and, when delivered and paid for in accordance with the terms of
the Purchase Agreement, will be valid and binding obligations of the Company enforceable against the Company in accordance with their
terms.
3. The Underlying Pre-Funded Warrants have been duly authorized by the Company for issuance upon exercise of the Series A
Warrants or the Series B Warrants, as applicable, in accordance with their terms, and, if issued today by the Company and assuming
due execution and delivery, against payment therefor upon exercise of the Series A Warrants or the Series B Warrants, as applicable,
would be valid and binding obligations of the Company, enforceable against the Company in accordance with their terms.
4. Assuming sufficient authorized but unissued shares of Common Stock are available for issuance when the Warrants or Underlying Pre-Funded
Warrants, as applicable, are exercised, the Warrant Shares, when issued upon exercise of the Warrants or Underlying Pre-Funded Warrants,
as applicable, in accordance with the terms of the Warrants or Underlying Pre-Funded Warrants, as applicable, will be validly issued,
fully paid and non-assessable.
The opinions expressed above are subject to bankruptcy, insolvency,
fraudulent transfer, reorganization, moratorium and other similar laws of general application affecting the rights and remedies of creditors
and to general principles of equity.
This opinion letter and the opinions it contains shall be interpreted
in accordance with the Core Opinion Principles as published in 74 Business Lawyer 815 (Summer 2019).
We hereby consent to the inclusion of this opinion as Exhibit 5.2
to the Current Report on Form 8-K and to the references to our firm under the caption “Legal Matters” in the Registration
Statement. In giving our consent, we do not admit that we are in the category of persons whose consent is required under Section 7
of the Securities Act or the rules and regulations thereunder.
Very truly yours,
/s/ Goodwin Procter LLP
GOODWIN PROCTER LLP
EX-10.1 — EXHIBIT 10.1
EX-10.1
Filename: tm2614922d1_ex10-1.htm · Sequence: 8
Exhibit 10.1
SECURITIES
PURCHASE AGREEMENT
This Securities Purchase Agreement
(this “Agreement”) is dated as of May 18, 2026, between Rapid Micro Biosystems, Inc., a Delaware corporation
(the “Company”), and the purchasers whose names and addresses are set forth on the signature pages hereof (each
a “Purchaser” and collectively, the “Purchasers”)
WHEREAS, subject to the terms
and conditions set forth in this Agreement and pursuant to an effective registration statement under the Securities Act of 1933, as amended
(the “Securities Act”), the Purchasers desire to purchase, severally and not jointly, and the Company has agreed to
sell, 71,607 shares (the “Common Shares’) of the Company’s Class A common stock, par value $0.01 per share
(the “Common Stock”) at a purchase price of $1.955 per share and accompanying Series A warrants (the “Series A
Common Warrants”) to purchase an aggregate of 71,607 shares of Common Stock (or pre-funded warrants in lieu thereof) with an
exercise price of $1.955 per share and Series B warrants (the “Series B Common Warrants”) to purchase an aggregate
of 71,607 shares of Common Stock (or pre-funded warrants in lieu thereof) with an exercise price of $2.34 per share in the forms attached
hereto as Exhibit A and Exhibit B, respectively.
NOW, THEREFORE, IN CONSIDERATION
of the mutual covenants contained in this Agreement, and for other good and valuable consideration the receipt and adequacy of which are
hereby acknowledged, the Company and the Purchasers agree, severally and not jointly, as follows:
ARTICLE I.
DEFINITIONS
1.1 Definitions.
In addition to the terms defined elsewhere in this Agreement, for all purposes of this Agreement, the following terms have the meanings
set forth in this Section 1.1:
“Action”
shall have the meaning ascribed to such term in Section 3.1(k).
“Affiliate”
means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control
with a Person as such terms are used in and construed under Rule 405 under the Securities Act.
“Base Prospectus”
means the final base prospectus included in the Registration Statement at the time of effectiveness.
“Board
of Directors” means the board of directors of the Company.
“Business
Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the United States or any day
on which the Trading Market and banking institutions in the State of New York are authorized or required by law or other governmental
action to close.
“Closing”
means the closing of the purchase and sale of Purchased Securities pursuant to Section 2.1.
“Closing
Date” means the Trading Day agreed to between the parties; provided all conditions precedent to (i) the Purchaser’s
obligations to pay the Subscription Amount and (ii) the Company’s obligations to deliver the Purchased Securities, in each
case, have been satisfied or waived.
“Commission”
means the United States Securities and Exchange Commission.
“Disclosure
Time” means, (i) if this Agreement is signed on a day that is not a Trading Day or after 9:00 a.m. (New York City
time) and before midnight (New York City time) on any Trading Day, 9:01 a.m. (New York City time) on the Trading Day immediately
following the date hereof, and (ii) if this Agreement is signed between midnight (New York City time) and 9:00 a.m. (New York
City time) on any Trading Day, no later than 9:01 a.m. (New York City time) on the date hereof.
“Exchange
Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder.
“FINRA”
shall have the meaning ascribed to such term in Section 3.1(e)
“GAAP”
means U.S. generally accepted accounting principles applied on a consistent basis during the periods
involved.
“Intellectual
Property” shall have the meaning ascribed to such term in Section 3.1(b).
“Liens”
means a lien, charge, pledge, security interest, encumbrance, right of first refusal, preemptive right or other restriction.
“Material
Adverse Effect” shall have the meaning assigned to such term in Section 3.1(b).
“Person”
means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability company,
joint stock company, government (or an agency or subdivision thereof) or other entity of any kind.
“Pre-Funded
Warrant” means the pre-funded warrant in the form attached hereto as Exhibit C.
“Proceeding”
means an action, claim, suit, investigation or proceeding (including, without limitation, an informal investigation or partial proceeding,
such as a deposition), whether commenced or threatened.
“Prospectus
Supplement” means the supplement to the Base Prospectus complying with Rule 424(b) of the Securities Act that is filed
with the Commission and delivered by the Company to the Purchaser on or prior to Closing, relating to the offer and sale of the Purchased
Securities to the Purchaser.
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“Purchase
Price” equals $1.955, subject to adjustment for reverse and forward stock splits, stock dividends, stock combinations and other
similar transactions of the Common Stock that occur after the date of this Agreement and prior to Closing.
“Purchased
Securities” means 71,607 shares of Common Stock, and the accompanying Series A Common Warrant and Series B Common
Warrant, issuable to the Purchasers pursuant to this Agreement.
“Registration
Statement” means the effective registration statement on Form S-3 filed with the Commission (File No. 333-276081)
pursuant to the Securities Act on December 15, 2023, which became effective on December 26, 2023, relating to the offer and
sale from time to time of the Company’s securities, including the Purchased Securities, including amendments, exhibits, schedules
and documents incorporated or deemed to be incorporated by reference therein and the documents otherwise deemed to a part thereof pursuant
to Rule 430A or 430B under the Securities Act.
“Required
Approvals” shall have the meaning ascribed to such term in Section 3.1(e).
“Rule 424”
means Rule 424 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted from
time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose and effect
as such Rule.
“SEC Reports”
shall have the meaning ascribed to such term in Section 3.1(h).
“Securities
Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.
“Shares”
means the Common Shares and Warrant Shares.
“Subscription
Amount" means the aggregate amount to be paid by a Purchaser to the Company for the Purchased Securities pursuant to the terms
and conditions of this Agreement calculated by multiplying the number of Common Shares purchased by a Purchaser by the Purchase Price.
“Subsidiaries”
means the subsidiaries of the Company.
“Trading
Day” means a day on which the principal Trading Market is open for trading.
“Trading
Market” means The Nasdaq Capital Market (or any successors thereto).
“Transfer
Agent” means Computershare Trust Company, N.A., and any successor transfer agent of the Company.
“Warrants”
means the Series A Common Warrants, Series B Common Warrants and the Pre-Funded Warrants.
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“Warrant
Shares” means the shares of Common Stock issuable upon exercise of the Series A Common Warrants and Series B Common
Warrants.
ARTICLE II.
PURCHASE AND SALE
2.1 Closing.
On the Closing Date, upon the terms and subject to the conditions set forth herein, the Company agrees to sell, and each Purchaser agrees,
severally and not jointly, to purchase, the number of Purchased Securities at the Purchase Price set forth opposite such Purchaser’s
name on Schedule A. The Subscription Amount shall be made available for “Delivery Versus Payment” settlement with the Company
or its designee. The Company and each Purchaser shall deliver the items set forth in Section 2.2 deliverable at the Closing.
Upon satisfaction of the covenants and conditions set forth in Section 2.2 and Section 2.3, the Closing shall
occur remotely as the parties shall mutually agree. Payment of the Subscription Amount for the Purchased Securities shall be made by each
Purchaser to the Company by wire transfer of immediately available funds to a bank account designated by the Company against delivery
to such Purchaser of the Purchased Shares registered in the Purchaser’s name and address or as otherwise directed to be registered
by the Purchaser, including but not limited to delivery through the facilities of The Depository Trust Company Deposit or Withdrawal at
Custodian system.
2.2 Deliveries.
(a) On
or prior to the Closing Date, the Company shall deliver or cause to be delivered to each Purchaser the following:
(i) this
Agreement duly executed by the Company;
(ii) the
Prospectus Supplement;
(iii) a
copy of the executed treasury direction to the Transfer Agent instructing the Transfer Agent to deliver the Common Shares, registered
in the name of such Purchaser or such other registration information as directed by such Purchaser;
(iv) the
Company’s wire instructions, on Company letterhead and signed by the Chief Executive Officer or Chief Financial Officer of the Company;
(v) a
certificate of good standing of the Company, dated within one (1) Business Day of the Closing Date, in form and substance reasonably
satisfactory to the Purchaser;
(vi) the
Purchased Securities (subject to receipt of the Subscription Amount).
(b) On
or prior to the Closing Date, each Purchaser shall deliver or cause to be delivered to the Company, the following:
(i) this
Agreement duly executed by such Purchaser; and
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(ii) the
Subscription Amount, with respect to the Purchased Securities purchased by such Purchaser, which shall be made available for “Delivery
Versus Payment” settlement with the Company or its designee.
2.3 Closing
Conditions.
(a) The
obligations of the Company hereunder in connection with the Closing are subject to the following conditions being met:
(i) the
accuracy in all material respects (or, to the extent representations or warranties are qualified by materiality or Material Adverse Effect,
in all respects) on the Closing Date of the representations and warranties of such Purchaser contained herein (unless as of a specific
date therein in which case they shall be accurate as of such date);
(ii) all
obligations, covenants and agreements of such Purchaser required to be performed at or prior to the Closing Date shall have been performed;
(iii) the
delivery by such Purchaser of the items set forth in Section 2.2(b) of this Agreement; and
(iv) the
closing of the underwritten offering pursuant to the underwriting agreement, dated as of the date hereof, by and among the Company, TD
Securities (USA) LLC and Lake Street Capital Markets LLC, as representatives of the several underwriters named therein (the “Offering”).
(b) The
obligations of each Purchaser hereunder in connection with the Closing are subject to the following conditions being met:
(i) the
accuracy in all material respects (or, to the extent representations or warranties are qualified by materiality or Material Adverse Effect,
in all respects) when made and on the Closing Date of the representations and warranties of the Company contained herein (unless as of
a specific date therein in which case they shall be accurate as of such date);
(ii) all
obligations, covenants and agreements of the Company required to be performed at or prior to the Closing Date shall have been performed;
(iii) the
delivery by the Company of the items set forth in Section 2.2(a) of this Agreement;
(iv) there
shall have been no Material Adverse Effect with respect to the Company since the date hereof;
(v) no
stop order or cease trade order suspending the effectiveness of the Registration Statement or any part thereof, preventing or suspending
the use of the Base Prospectus or the Prospectus Supplement or any part thereof shall have been issued, and no proceedings for that purpose
shall have been initiated or threatened; and
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(vi) the
closing of the Offering.
ARTICLE III.
REPRESENTATIONS AND WARRANTIES
3.1 Representations
and Warranties of the Company. The Company hereby represents and warrants as of the date hereof and as of the Closing Date to the
Purchaser as follows (unless as of a specific date therein, in which case they shall be accurate as of such date):
(a) Subsidiaries.
The Company does not own or control, directly or indirectly, any corporation, association or other entity other than the subsidiaries
listed in Exhibit 21 to the Company’s Annual Report on Form 10-K for the year ended December 31, 2025.
(b) Organization
and Qualification. The Company and each of its Subsidiaries have been duly organized and are validly existing and in good standing
under the laws of their respective jurisdictions of organization, are duly qualified to do business and are in good standing in each jurisdiction
in which their respective ownership or lease of property or the conduct of their respective businesses requires such qualification, and
have all power and authority necessary to own or hold their respective properties and to conduct the businesses in which they are engaged,
except where the failure to be so qualified or in good standing or have such power or authority would not, individually or in the aggregate,
have a material adverse effect on the business, properties, management, financial position, stockholders’ equity, results of operations
or prospects of the Company and its subsidiaries taken as a whole or on the performance by the Company of its obligations under this Agreement
(a “Material Adverse Effect”).
(c) Authorization;
Enforcement. The Company has the requisite corporate power and authority to enter into and to consummate the transactions contemplated
by this Agreement and otherwise to carry out its obligations hereunder. The execution and delivery of this Agreement by the Company and
the consummation by it of the transactions contemplated hereby have been duly authorized by all necessary action on the part of the Company
and no further action is required by the Company, the Board of Directors or the Company’s stockholders in connection herewith other
than in connection with the Required Approvals. This Agreement has been (or upon delivery will have been) duly executed by the Company
and, when delivered in accordance with the terms hereof and thereof, will constitute the valid and binding obligation of the Company enforceable
against the Company in accordance with its terms, except (i) as limited by general equitable principles and applicable bankruptcy,
insolvency, reorganization, moratorium and other laws of general application affecting enforcement of creditors’ rights generally,
(ii) as limited by laws relating to the availability of specific performance, injunctive relief or other equitable remedies and (iii) insofar
as indemnification and contribution provisions may be limited by applicable law.
6
(d) No
Conflicts. The execution, delivery and performance by the Company of this Agreement, the issuance and sale of the Purchased Securities
and the consummation by it of the transactions contemplated hereby do not and will not (i) conflict with or violate any provision
of the Company’s certificate of incorporation, bylaws or other organizational or charter documents, or (ii) contravene or constitute
a default (or an event that with notice or lapse of time or both would become a default) under any agreement or other instrument binding
upon the Company or its Subsidiary that is material to the Company and its Subsidiary, taken as a whole, or result in the creation of
any Lien upon any of the properties or assets of the Company or give to others any rights of termination, amendment, anti-dilution or
similar adjustments, acceleration or cancellation (with or without notice, lapse of time or both), or (iii) subject to the Required
Approvals, conflict with or result in a violation of any applicable law, rule, regulation, order, judgment, injunction, decree or other
restriction of any court or governmental authority to which the Company or its Subsidiary is subject (including federal, and state securities
laws and regulations), or by which any property or asset of the Company or its Subsidiary is bound or affected; except in the case of
each of clauses (ii) and (iii), such as could not have or reasonably be expected to result in a Material Adverse Effect.
(e) Filings,
Consents and Approvals. The Company is not required to obtain any consent, waiver, authorization or order of, give any notice to,
or make any filing or registration with, any court or other federal, state, local or other governmental authority, or the Financial Industry
Regulatory Authority (“FINRA”), or other Person in connection with the execution, delivery and performance by the Company
of this Agreement, other than: (i) the filing with the Commission of the Prospectus Supplement, and (ii) such filings as are
required to be made under applicable state securities laws (collectively, the “Required Approvals”).
(a) Issuance
of the Purchased Securities; Registration. The Common Shares are duly authorized and, when issued and paid for in accordance with
this Agreement, will be duly and validly issued, fully paid and non-assessable, free and clear of all Liens. The Company has prepared
and filed the Registration Statement in conformity with the requirements of the Securities Act, including the Base Prospectus, and such
amendments and supplements thereto as may have been required to the date of this Agreement. The Registration Statement is effective under
the Securities Act and no stop order preventing or suspending the effectiveness of the Registration Statement or suspending or preventing
the use of the Prospectus Supplement has been issued by the Commission and no proceedings for that purpose or pursuant to Section 8A
under the Securities Act have been instituted or, to the knowledge of the Company, are threatened by the Commission. Promptly after execution
and delivery of this Agreement, the Company shall file the Prospectus Supplement with the Commission pursuant to Rule 424(b) within
the time period required under Rule 424(b), and in no event later than the Closing Date. At the time the Registration Statement and
any amendments thereto became effective, at the date of this Agreement and at the Closing Date, the Registration Statement and any amendments
thereto conformed and will conform in all material respects to the requirements of the Securities Act and did not and will not contain
any untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary to make the statements
therein not misleading; and the Prospectus Supplement and any amendments or supplements thereto, as of the date of the Prospectus Supplement
or any amendment or supplement thereto and at the Closing Date, conformed and will conform in all material respects to the requirements
of the Securities Act and the applicable rules and regulations of the Commission thereunder and did not and will not contain an untrue
statement of a material fact or omit to state a material fact necessary in order to make the statements therein, in the light of the circumstances
under which they were made, not misleading. The Series A Common Warrants and Series B Common Warrants have been duly and validly
authorized by the Company, and when executed and delivered by the Company, will be valid and binding agreements of the Company, enforceable
against the Company in accordance with their terms, except as the enforcement thereof may be limited by bankruptcy, insolvency, reorganization,
moratorium or other similar laws relating to or affecting the rights and remedies of creditors or by general equitable principles. The
Warrant Shares have been duly and validly authorized and reserved for issuance upon exercise of the Warrants, respectively, in a number
sufficient to meet the current exercise requirements. The Warrant Shares, when issued and delivered upon exercise of the Warrants and
in accordance therewith, will be duly and validly issued, fully paid and non-assessable.
7
(f) Listing.
The Company has filed a Listing of Additional Shares Notification with the Nasdaq Capital Market with respect to the Shares.
(g) Capitalization.
The capitalization of the Company is as set forth in the SEC Reports. All the outstanding shares of capital stock of the Company have
been duly and validly authorized and issued and are fully paid and non-assessable and are not subject to any pre-emptive or similar rights
that have not been duly waived or satisfied; except as described in or expressly contemplated by the Registration Statement, and the Prospectus,
there are no outstanding rights (including, without limitation, pre-emptive rights that have not been duly waived or satisfied), warrants
or options to acquire, or instruments convertible into or exchangeable for, any shares of capital stock or other equity interest in the
Company or any of its subsidiaries, or any contract, commitment, agreement, understanding or arrangement of any kind relating to the issuance
of any capital stock of the Company or any such subsidiary, any such convertible or exchangeable securities or any such rights, warrants
or options; all outstanding shares of capital stock of the Company conform, and the Purchased Securities, when they have been delivered
and paid for in accordance with this Agreement, will conform, in all material respects to the description thereof contained in the Registration
Statement and the Prospectus; and all the outstanding shares of capital stock or other equity interests of each subsidiary owned, directly
or indirectly, by the Company have been duly and validly authorized and issued, are fully paid and non-assessable and are owned directly
or indirectly by the Company, free and clear of any lien, charge, encumbrance, security interest, restriction on voting or transfer or
any other claim of any third party.
(h) SEC
Reports; Financial Statements. The Company has filed all reports, schedules, forms, statements and other documents required to be
filed by the Company under the Securities Act and the Exchange Act, including pursuant to Section 13(a) or 15(d) thereof,
for the two years preceding the date hereof (the foregoing materials, including the exhibits thereto and documents incorporated by reference
therein, being collectively referred to herein as the “SEC Reports”) on a timely basis or has received a valid extension
of such time of filing and has filed any such SEC Reports prior to the expiration of any such extension. As of their respective dates,
the SEC Reports complied in all material respects with the requirements of the Securities Act and the Exchange Act, as applicable, and
none of the SEC Reports, when filed, contained any untrue statement of a material fact or omitted to state a material fact required to
be stated therein or necessary in order to make the statements therein, in the light of the circumstances under which they were made,
not misleading. The financial statements of the Company (or any predecessor entity thereof) included in the SEC Reports comply in all
material respects with applicable accounting requirements and the rules and regulations of the Commission with respect thereto as
in effect at the time of filing. Such financial statements have been prepared in accordance with GAAP, except as may be otherwise specified
in such financial statements or the notes thereto and except that unaudited financial statements may not contain all footnotes required
by GAAP, and fairly present in all material respects the financial position of the Company and its Subsidiary as of and for the dates
thereof and the results of operations and cash flows for the periods then ended, subject, in the case of unaudited statements, to normal,
immaterial, year-end audit adjustments.
8
(i) Company
Not Ineligible Issuer. At the time of filing the Registration Statement and any post-effective amendment thereto, at the earliest
time thereafter that the Company or another offering participant made a bona fide offer (within the meaning of Rule 164(h)(2) of
the Securities Act) of the Purchased Securities and at the date hereof, the Company was not and is not an “ineligible issuer,”
as defined in Rules 164, 405, and 433 under the Securities Act (without taking account of any determination by the Commission pursuant
to Rule 405 that it is not necessary that the Company be considered an ineligible issuer). Any free writing prospectus that the Company
is required to file pursuant to Rule 433(d) under the Securities Act has been, or will be, filed with the Commission in accordance
with the requirements of the Securities Act and the applicable rules and regulations of the Commission thereunder. Each free writing
prospectus that the Company has filed, or is required to file, pursuant to Rule 433(d) under the Securities Act or that was
prepared by or on behalf of or used or referred to by the Company complies or will comply, as of the date of such filing, in all material
respects with the applicable requirements of the Securities Act and the applicable rules and regulations of the Commission thereunder.
(j) Material
Changes; Undisclosed Events, Liabilities or Developments. Since the date of the latest audited financial statements included within
the SEC Reports, (i) there has been no event, occurrence or development that has had or that could reasonably be expected to result
in a Material Adverse Effect, (ii) the Company has not incurred any material liabilities (contingent or otherwise) other than (A) trade
payables and accrued expenses incurred in the ordinary course of business consistent with past practice and (B) liabilities not required
to be reflected in the Company’s financial statements pursuant to GAAP or disclosed in filings made with the Commission, (iii) the
Company has not altered its method of accounting, and (iv) the Company has not declared or made any dividend or distribution of cash
or other property to its stockholders or purchased, redeemed or made any agreements to purchase or redeem any shares of its capital stock.
(k) Litigation.
There is no action, suit, inquiry, notice of violation, proceeding or investigation pending or, to the knowledge of the Company, threatened
against or affecting the Company, any Subsidiary or any of their respective properties before or by any court, arbitrator, governmental
or administrative agency or regulatory authority (federal, state, county, local or foreign) (collectively, an “Action”)
which (i) adversely affects or challenges the legality, validity or enforceability of this Agreement or the issuance and sale of
the Purchased Securities or (ii) could, if there were an unfavorable decision, have or reasonably be expected to result in a Material
Adverse Effect. Neither the Company nor any Subsidiary, nor any director or officer thereof, is or has been the subject of any Action
involving a claim of violation of or liability under federal or state securities laws or a claim of breach of fiduciary duty. There has
not been, and to the knowledge of the Company, there is not pending or contemplated, any investigation by the Commission involving the
Company or any current or former director or officer of the Company.
9
(l) Compliance.
Upon the execution and delivery by the Company of, and the performance by the Company of its obligations under, this Agreement, neither
the Company nor any Subsidiary will be: (i) in default under or in violation of (and no event has occurred that has not been waived
that, with notice or lapse of time or both, would result in a default by the Company or a Subsidiary under) any indenture, loan or credit
agreement or any other agreement or instrument to which it is a party or by which it or any of its properties is bound (whether or not
such default or violation has been waived), (ii) in violation of any judgment, decree or order of any court, arbitrator or other
governmental authority or (iii) in violation of any statute, rule, ordinance, regulation or guidance of any governmental authority,
including without limitation all foreign, federal, state and local laws relating to taxes, environmental protection, occupational health
and safety, product quality and safety and employment and labor matters, except in each case as could not have or reasonably be expected
to result in a Material Adverse Effect.
(b) Title
to Intellectual Property. (i) The Company and its Subsidiaries own, or have obtained valid and enforceable licenses for, all
inventions (including any “subject inventions” developed with government funding as described in clause (ii) below),
patents, patent applications, trademarks, service marks, trade names, trademark registrations, service mark registrations, domain names
and other source indicators, copyrights and copyrightable works, know-how, trade secrets, systems, procedures, proprietary or confidential
information and all other worldwide intellectual property, industrial property and proprietary rights (collectively, “Intellectual
Property”) used or proposed to be used in the current and proposed conduct of their respective businesses; (ii) as contemplated
under the Bayh Dole Act and its implementing regulations, the Company has timely submitted notices of election to retain title to any
material subject invention the Company developed using government funding; (iii) to the knowledge of the Company, the Company’s
and its subsidiaries’ conduct of their respective businesses does not infringe, misappropriate or otherwise violate any intellectual
property of any person except those that would not reasonably be expected, individually or in the aggregate, to have a Material Adverse
Effect; (iv) the Company and its subsidiaries have not received any written notice of any claim relating to Intellectual Property
and, to the knowledge of the Company, no such claims have been threatened, except any such notice of claim or threatened claim that would
not reasonably be expected, individually or in the aggregate, to have a Material Adverse Effect; (v) to the knowledge of the Company,
the Intellectual Property of the Company and its subsidiaries is valid and enforceable and is not being infringed, misappropriated or
otherwise violated by any person in any respect that would reasonably be expected, individually or in the aggregate, to have a Material
Adverse Effect; (vi) the Company and its subsidiaries have complied in all material respects with the terms of each agreement pursuant
to which Intellectual Property has been licensed to the Company or any subsidiary, and all such agreements are in full force and effect;
and (vii) the Company and its subsidiaries have taken commercially reasonable steps to protect, maintain and safeguard the Intellectual
Property owned by them, including the execution of appropriate nondisclosure, confidentiality agreements and invention assignment agreements
by their employees and contractors, and, to the Company’s knowledge, no employee or contractor of the Company is in or has been
in violation in a material respect of any term of any employment contract, patent disclosure agreement, invention assignment agreement,
non-competition agreement, non-solicitation agreement, nondisclosure agreement, or any restrictive covenant to or with a former employer
where the basis of such violation relates to such employee’s employment with the Company.
10
(m) No
Undisclosed Relationships. No relationship, direct or indirect, exists between or among the Company or its Subsidiary, on the one
hand, and the directors, officers, stockholders, customers, suppliers or other affiliates of the Company or its Subsidiary, on the other,
that is required by the Securities Act to be described in the SEC Reports and that is not so described in such filings.
(n) Licenses
and Permits. The Company and its Subsidiaries possess all licenses, sub-licenses, certificates, certifications, permits and other
authorizations issued by, and have made all declarations and filings with, the appropriate federal, state, local or foreign governmental
or regulatory authorities or national standards bodies that are necessary for the ownership or lease of their respective properties or
the conduct of their respective businesses as described in each of the Registration Statement and the Prospectus, except where the failure
to possess or make the same would not, whether individually or in the aggregate, reasonably be expected to have a Material Adverse Effect;
and except as described in each of the Registration Statement and the Prospectus, neither the Company nor any of its subsidiaries has
received notice of any revocation or modification of any such license, sub-license, certificate, certification, permit or authorization
or has any reason to believe that any such license, sub-license, certificate, permit or authorization will not be renewed in the ordinary
course except where such revocation or modifications would not, whether individually or in the aggregate, reasonably be expected to have
a Material Adverse Effect.
(o) Sarbanes-Oxley;
Internal Accounting Controls. There is and, since the effectiveness of the Registration Statement, there has been no failure on the
part of the Company or, to the knowledge of the Company, any of the Company’s directors or officers, in their capacities as such,
to comply in all material respects with any provision of the Sarbanes-Oxley Act of 2002, as amended and the rules and regulations
promulgated in connection therewith, including Section 402 related to loans.
(p) Investment
Company. The Company is not, and is not an Affiliate of, and immediately after receipt of payment for the Common Shares, will not
be or be an Affiliate of, an “investment company” within the meaning of the Investment Company Act of 1940, as amended.
11
(q) Listing
and Maintenance Requirements. The Company is subject to and in compliance in all material respects with the reporting requirements
of Section 13 or Section 15(d) of the Exchange Act. The Common Stock is registered pursuant to Section 12(b) or
Section 12(g) of the Exchange Act and is listed on Nasdaq, and the Company has taken no action designed to, or reasonably likely
to have the effect of, terminating the registration of the Common Stock under the Exchange Act or delisting the Common Stock from Nasdaq,
nor has the Company received any notification that the Commission or Nasdaq is contemplating terminating such registration or listing.
(r) Disclosure.
Except with respect to the material terms and conditions of the transactions contemplated by this Agreement, the Company confirms that
neither it nor any other Person acting on its behalf has provided each Purchaser or its agents or counsel with any information that it
believes constitutes or might constitute material, non-public information that is not otherwise disclosed in the Prospectus Supplement
or the SEC Reports. The Company understands and confirms that the Purchasers will rely on the foregoing representation in effecting transactions
in securities of the Company. All of the disclosure furnished by or on behalf of the Company to the Purchasers regarding the Company and
its Subsidiary, their respective businesses and the transactions contemplated hereby, is true and correct and does not contain any untrue
statement of a material fact or omit to state any material fact necessary in order to make the statements made therein, in the light of
the circumstances under which they were made, not misleading. The Company acknowledges and agrees that each Purchaser makes or has made
no representations or warranties with respect to the transactions contemplated hereby other than those specifically set forth in Section 3.2
hereof.
(s) Accountants.
PricewaterhouseCoopers LLP, who has certified certain financial statements of the Company and its subsidiaries, is an independent registered
public accounting firm with respect to the Company and its subsidiaries within the applicable rules and regulations adopted by the
Commission and the Public Company Accounting Oversight Board (United States) and as required by the Securities Act.
(t) Acknowledgment
Regarding Purchaser’s Purchase of Securities. The Company acknowledges and agrees that each Purchaser is acting solely in the
capacity of an arm’s length purchaser with respect to this Agreement and the transactions contemplated hereby. The Company further
acknowledges that each Purchaser is not acting as a financial advisor or fiduciary of the Company (or in any similar capacity) with respect
to this Agreement and the transactions contemplated hereby and any advice given by such Purchaser or any of their respective representatives
or agents in connection with this Agreement and the transactions contemplated hereby is merely incidental to the Purchaser’s purchase
of the Purchased Securities. The Company further represents to each Purchaser that the Company’s decision to enter into this Agreement
has been based solely on the independent evaluation of the transactions contemplated hereby by the Company and its representatives.
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(u) Statements.
Neither the Company, its Subsidiaries, nor to the Company’s knowledge, any of their respective officers, employees or agents has
made any untrue statement of a material fact or fraudulent statement to any governmental authority or failed to disclose a material fact
required to be disclosed to such governmental authority. All material reports, documents, claims and notices required or requested to
be filed, maintained or furnished under any Applicable Regulatory Law by Company or its Subsidiaries, have been so filed, maintained or
furnished and were complete and correct in all material respects.
3.2 Representations
and Warranties of the Purchasers. Each Purchaser, severally and not jointly, hereby represents and warrants as of the date
hereof and as of the Closing Date to the Company as follows (unless as of a specific date therein, in which case they shall be accurate
as of such date):
(a) Authority.
The execution and delivery of this Agreement and performance by such Purchaser of the transactions contemplated by this Agreement have
been duly authorized by all necessary action on the part of the Purchaser. This Agreement has been duly executed by such Purchaser, and
when delivered by such Purchaser in accordance with the terms hereof, will constitute the valid and legally binding obligation of such
Purchaser, enforceable against it in accordance with its terms, except: (i) as limited by general equitable principles and applicable
bankruptcy, insolvency, reorganization, moratorium and other laws of general application affecting enforcement of creditors’ rights
generally, (ii) as limited by laws relating to the availability of specific performance, injunctive relief or other equitable remedies
and (iii) insofar as indemnification and contribution provisions may be limited by applicable law.
(b) Understandings
or Arrangements. Such Purchaser is acquiring the Purchased Securities as principal for its own account and has no direct or indirect
arrangement or understandings with any other persons to distribute or regarding the distribution of such Purchased Securities (this representation
and warranty not limiting such Purchaser’s right to sell the Purchased Securities in compliance with applicable federal and state
securities laws).
(c) Experience
of the Purchaser. Such Purchaser, either alone or together with its representatives, has such knowledge, sophistication and experience
in business and financial matters so as to be capable of evaluating the merits and risks of the prospective investment in the Purchased
Securities, and has so evaluated the merits and risks of such investment. The Purchaser is able to bear the economic risk of an investment
in the Purchased Securities and, at the present time, is able to afford a complete loss of such investment.
(d) Access
to Information. The Purchaser acknowledges that it has had the opportunity to review this Agreement (including all exhibits and schedules
thereto) and the SEC Reports and has been afforded, (i) the opportunity to ask such questions as it has deemed necessary of, and
to receive answers from, representatives of the Company concerning the terms and conditions of the offering of the Purchased Securities
and the merits and risks of investing in the Purchased Securities; (ii) access to information about the Company and its financial
condition, results of operations, business, properties, management and prospects sufficient to enable it to evaluate its investment; and
(iii) the opportunity to obtain such additional information that the Company possesses or can acquire without unreasonable effort
or expense that is necessary to make an informed investment decision with respect to the investment.
13
The Company acknowledges and agrees that the representations
contained in this Section 3.2 shall not modify, amend or affect such Purchaser’s right to rely on the Company’s
representations and warranties contained in this Agreement or any other document or instrument executed and/or delivered in connection
with this Agreement or the consummation of the transactions contemplated hereby.
ARTICLE IV.
OTHER AGREEMENTS OF THE PARTIES
4.1 Use
of Proceeds. The Company will use the net proceeds as described in the Prospectus Supplement under the section entitled “Use
of Proceeds.”
ARTICLE V.
MISCELLANEOUS
5.1 Entire
Agreement. This Agreement contains the entire understanding of the parties with respect to the subject matter hereof and supersedes
all prior agreements and understandings, oral or written, with respect to such matters, which the parties acknowledge have been merged
into this Agreement.
5.2 Notices.
Any and all notices or other communications or deliveries required or permitted to be provided hereunder shall be in writing and shall
be deemed given and effective on the earliest of: (a) the time of transmission, if such notice or communication is delivered via
facsimile at the facsimile number or email attachment at the email address as set forth on the signature pages attached hereto at
or prior to 5:30 p.m. (New York City time) on a Trading Day, (b) the next Trading Day after the time of transmission, if such
notice or communication is delivered via facsimile at the facsimile number or email attachment at the email address as set forth on the
signature pages attached hereto on a day that is not a Trading Day or later than 5:30 p.m. (New York City time) on any Trading
Day, (c) the second (2nd) Trading Day following the date of mailing, if sent by U.S. nationally recognized overnight courier
service or (d) upon actual receipt by the party to whom such notice is required to be given. The address for such notices and communications
shall be as set forth on the signature pages attached hereto. To the extent that any notice provided pursuant to this Agreement constitutes,
or contains, material, non-public information regarding the Company or its Subsidiaries, the Company shall simultaneously file such notice
with the Commission pursuant to a Current Report on Form 8-K.
5.3 Amendments;
Waivers. No provision of this Agreement may be waived, modified, supplemented or amended except in a written instrument signed, in
the case of an amendment, by the Company and the Purchasers holding at least a majority of the Purchased Securities then held by Purchasers;
provided that if any amendment or waiver disproportionately and adversely affects a Purchaser (or group of Purchasers) in any material
respect, the consent of such disproportionately affected Purchaser (or group of Purchasers) shall also be required. No waiver of any default
with respect to any provision, condition or requirement of this Agreement shall be deemed to be a continuing waiver in the future or a
waiver of any subsequent default or a waiver of any other provision, condition or requirement hereof, nor shall any delay or omission
of any party to exercise any right hereunder in any manner impair the exercise of any such right. Any amendment effected in accordance
with this Section 5.3 shall be binding upon the Purchasers and the Company.
14
5.4 Headings.
The headings herein are for convenience only, do not constitute a part of this Agreement and shall not be deemed to limit or affect any
of the provisions hereof.
5.5 Successors
and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their successors and permitted assigns.
Neither party may assign this Agreement or any rights or obligations hereunder without the prior written consent of the other party (other
than by merger).
5.6 No
Third-Party Beneficiaries. This Agreement is intended for the benefit of the parties hereto and their respective successors and permitted
assigns and is not for the benefit of, nor may any provision hereof be enforced by, any other Person.
5.7 Governing
Law. All questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by and
construed and enforced in accordance with the laws of the State of Delaware, without regard to the principles of conflicts of law thereof.
Each party agrees that all legal Proceedings concerning the interpretations, enforcement and defense of the transactions contemplated
by this Agreement (whether brought against a party hereto or its respective Affiliates, directors, officers, shareholders, partners, members,
employees or agents) shall be commenced exclusively in the state and federal courts sitting in Delaware. Each party hereby irrevocably
submits to the exclusive jurisdiction of the state and federal courts sitting in Delaware, for the adjudication of any dispute hereunder
or in connection herewith or with any transaction contemplated hereby or discussed herein (including with respect to the enforcement of
this Agreement), and hereby irrevocably waives, and agrees not to assert in any Action or Proceeding, any claim that it is not personally
subject to the jurisdiction of any such court, that such Action or Proceeding is improper or is an inconvenient venue for such Proceeding.
Each party hereby irrevocably waives personal service of process and consents to process being served in any such Action or Proceeding
by mailing a copy thereof via registered or certified mail or overnight delivery (with evidence of delivery) to such party at the address
in effect for notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process
and notice thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process in any other manner permitted
by law. If any party shall commence an Action or Proceeding to enforce any provisions of this Agreement, then the prevailing party in
such Action or Proceeding shall be reimbursed by the non-prevailing party for its reasonable attorneys’ fees and other costs and
expenses incurred with the investigation, preparation and prosecution of such Action or Proceeding.
5.8 Execution.
This Agreement may be executed in two or more counterparts, all of which when taken together shall be considered one and the same agreement
and shall become effective when counterparts have been signed by each party and delivered to each other party, it being understood that
the parties need not sign the same counterpart. In the event that any signature is delivered by facsimile transmission or by e-mail delivery
of a “.pdf” format data file, such signature shall create a valid and binding obligation of the party executing (or on whose
behalf such signature is executed) with the same force and effect as if such facsimile or “.pdf” signature page were
an original thereof.
15
5.9 Severability.
If any term, provision, covenant or restriction of this Agreement is held by a court of competent jurisdiction to be invalid, illegal,
void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein shall remain in full force
and effect and shall in no way be affected, impaired or invalidated, and the parties hereto shall use their commercially reasonable efforts
to find and employ an alternative means to achieve the same or substantially the same result as that contemplated by such term, provision,
covenant or restriction. It is hereby stipulated and declared to be the intention of the parties that they would have executed the remaining
terms, provisions, covenants and restrictions without including any of such that may be hereafter declared invalid, illegal, void or unenforceable.
5.10 Remedies.
In addition to being entitled to exercise all rights provided herein or granted by law, including recovery of damages, the Purchaser and
the Company will be entitled to specific performance under this Agreement. The parties agree that monetary damages may not be adequate
compensation for any loss incurred by reason of any breach of obligations contained in this Agreement and hereby agree to waive and not
to assert in any Action for specific performance of any such obligation the defense that a remedy at law would be adequate.
5.11 Saturdays,
Sundays, Holidays, etc. If the last or appointed day for
the taking of any action or the expiration of any right required or granted herein shall not be a Business Day, then such action may be
taken or such right may be exercised on the next succeeding Business Day.
5.12 Construction.
The parties agree that each of them and/or their respective counsel have reviewed and had an opportunity to revise this Agreement and,
therefore, the normal rule of construction to the effect that any ambiguities are to be resolved against the drafting party shall
not be employed in the interpretation of this Agreement or any amendments thereto. In addition, each and every reference to share prices
and shares of common stock in this Agreement shall be subject to adjustment for reverse and forward stock splits, stock dividends, stock
combinations and other similar transactions of the common stock that occur after the date of this Agreement.
5.13 WAIVER
OF JURY TRIAL. IN ANY ACTION, SUIT, OR PROCEEDING IN ANY JURISDICTION BROUGHT BY ANY PARTY AGAINST ANY OTHER PARTY, THE PARTIES
EACH KNOWINGLY AND INTENTIONALLY, TO THE GREATEST EXTENT PERMITTED BY APPLICABLE LAW, HEREBY ABSOLUTELY, UNCONDITIONALLY, IRREVOCABLY
AND EXPRESSLY WAIVES FOREVER TRIAL BY JURY.
(Signature Pages Follow)
16
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
RAPID MICRO BIOSYSTEMS, INC.
Address for Notices:
By:
/s/ Richard Kollender
1001 Pawtucket
Boulevard West,
Name: Richard Kollender
Title: Director
Suite 280, Lowell, MA 01854,
With a copy to:
Goodwin Procter LLP
100 Northern Avenue
Boston, MA 02210
Attention: John Egan and Katie Hand
Email: JEgan@goodwinlaw.com;
Khand@goodwinlaw.com
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Kirk Malloy
Kirk Malloy
18
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Inese Lowenstein
Inese Lowenstein
19
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Melinda Litherland
Melinda Litherland
20
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Robert Spignesi
Robert Spignesi
21
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Sean Wirtjes
Sean Wirtjes
22
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Todd Ballantyne
Todd Ballantyne
23
IN WITNESS WHEREOF, the parties
hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories as of the date first
indicated above.
PURCHASER:
By:
/s/ Julie Jarvie
Julie Jarvie
24
SCHEDULE A
PURCHASERS
Exhibit A
Form of Series A Warrant
Exhibit B
Form of Series B Warrant
26
Exhibit C
Form of Pre-Funded Warrant
27
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May 18, 2026
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