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Form 8-K

sec.gov

8-K — ONCOLYTICS BIOTECH INC

Accession: 0001104659-26-081797

Filed: 2026-07-08

Period: 2026-07-06

CIK: 0001129928

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Changes in Registrant's Certifying Accountant

Item: Financial Statements and Exhibits

Documents

8-K — tm2620055d1_8k.htm (Primary)

EX-16.1 — EXHIBIT 16.1 (tm2620055d1_ex16-1.htm)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):

July 6, 2026

Oncolytics

Biotech Inc.

(Exact name of registrant as specified in its charter)

Nevada

001-38512

98-0541667

(State or other

jurisdiction

of incorporation)

(Commission File Number)

(IRS Employer

Identification No.)

4350 Executive Drive, Suite 325

San Diego, CA 92121

92121

(Address of principal executive offices)

(Zip Code)

(403) 670-7377

(Registrant's telephone number, including area code)

N/A

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended

to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title

of each class

Trading

Symbol(s)

Name

of each exchange on which registered

Common stock, par value $0.001 per share

ONCY

The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405

of this chapter) or Rule 12b-2 of the Exchange Act (§240.12b-2 of this chapter).

Emerging growth company ¨

If an emerging growth company, indicate by check

mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting

standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Item 4.01. Changes in Registrant’s Certifying Accountant.

On July 6, 2026, due to the

Company’s corporate restructuring, the Audit Committee of the Board of Directors of Oncolytics Biotech Inc. (the “Company”),

unanimously voted to disengage Ernst & Young LLP (“EY”) as the Company’s independent registered public accounting

firm and to engage Baker Tilly US, LLP (“Baker Tilly”) as the Company’s independent registered public accounting

firm for the 2026 fiscal year, subject to completion of Baker Tilly’s client acceptance procedures.

EY’s reports on the

Company’s financial statements for each of the fiscal years ended December 31, 2025 and December 31, 2024 did not contain an adverse

opinion or a disclaimer of opinion and were not qualified or modified as to uncertainty, audit scope, or accounting principles, except

EY’s reports contained an explanatory paragraph regarding the Company’s ability to continue as a going concern. During the

Company’s fiscal years ended December 31, 2025 and December 31, 2024, and through the date of change, there were no disagreements

with EY on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedure which, if

not resolved to the satisfaction of EY, would have caused EY to make reference to the subject matter of the disagreement in connection

with its report.

During the fiscal years ended

December 31, 2025 and December 31, 2024 and the subsequent period through the date of change, there have been no reportable events within

the meaning of Item 304(a)(1)(v) of Regulation S-K promulgated by the Securities and Exchange Commission (the “SEC”).

During the fiscal years ended

December 31, 2025 and December 31, 2024 and the subsequent period to the date of its engagement, neither the Company nor anyone acting

on its behalf has consulted with Baker Tilly regarding (i) the application of accounting principles to a specific transaction, either

completed or proposed, or the type of audit opinion that might be rendered on the Company’s financial statements, and neither a

written report or oral advice was provided to the Company that Baker Tilly concluded was an important factor considered by the Company

in reaching a decision as to any accounting, auditing, or financial reporting issue; (ii) any matter that was the subject of a disagreement

within the meaning of Item 304(a)(1)(iv) of Regulation S-K; or (iii) any reportable event within the meaning of Item 304(a)(1)(v) of Regulation

S-K.

The Company provided EY with

a copy of this Form 8-K on July 7, 2026, and requested that EY furnish it with a letter addressed to the SEC stating whether it agrees

with the statements made by the Company in this Item 4.01 concerning EY, and, if not, stating the respects in which it does not agree.

The letter of EY addressed to the SEC is attached hereto as Exhibit No. 16.1.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.

Description

16.1

Letter from Ernst & Young LLP, dated July 7, 2026.

104

Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURE

Pursuant to the requirements of the Securities

Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly

authorized.

Date: July 8, 2026

ONCOLYTICS BIOTECH INC.

By:

/s/ Kirk Look

Name:

Kirk Look

Title:

Chief Financial Officer

EX-16.1 — EXHIBIT 16.1

EX-16.1

Filename: tm2620055d1_ex16-1.htm · Sequence: 2

Exhibit 16.1

July 7, 2026

Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Commissioners:

We have read Item 4.01 of Form 8-K dated July 7, 2026, of Oncolytics

Biotech Inc. and are in agreement with the statements contained in the second, third and fifth paragraphs of Item 4.01. We have no basis

to agree or disagree with other statements of the registrant contained therein.

/s/ Ernst & Young LLP

Calgary, Canada

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Entity Central Index Key

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Entity Tax Identification Number

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Entity Incorporation, State or Country Code

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Entity Address, Address Line One

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Entity Address, Address Line Two

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Entity Address, City or Town

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Entity Address, State or Province

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Entity Address, Postal Zip Code

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City Area Code

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Local Phone Number

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