Form 8-K

8-K — Xenetic Biosciences, Inc.

Accession: 0001683168-26-007340

Filed: 2026-09-23

Period: 2026-09-23

CIK: 0001534525

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Regulation FD Disclosure

Item: Financial Statements and Exhibits

Documents

8-K — xenetic_8k.htm (Primary)

EX-99.1 — INVESTOR PRESENTATION (xenetic_ex9901.htm)

GRAPHIC (image_027.jpg)

GRAPHIC (image_028.jpg)

GRAPHIC (image_029.jpg)

GRAPHIC (image_030.jpg)

GRAPHIC (image_031.jpg)

GRAPHIC (image_032.jpg)

GRAPHIC (image_033.jpg)

GRAPHIC (image_034.jpg)

GRAPHIC (image_035.jpg)

GRAPHIC (image_036.jpg)

GRAPHIC (image_037.jpg)

GRAPHIC (image_038.jpg)

GRAPHIC (image_039.jpg)

GRAPHIC (image_040.jpg)

GRAPHIC (image_041.jpg)

GRAPHIC (image_042.jpg)

GRAPHIC (image_043.jpg)

GRAPHIC (image_044.jpg)

GRAPHIC (image_045.jpg)

GRAPHIC (image_046.jpg)

GRAPHIC (image_047.jpg)

GRAPHIC (image_048.jpg)

GRAPHIC (image_049.jpg)

GRAPHIC (image_050.jpg)

GRAPHIC (image_051.jpg)

GRAPHIC (image_052.jpg)

XML — IDEA: XBRL DOCUMENT (R1.htm)

8-K — CURRENT REPORT

8-K (Primary)

Filename: xenetic_8k.htm · Sequence: 1

Xenetic Biosciences, Inc. 8-K

false

0001534525

2026-09-23

iso4217:USD

xbrli:shares

iso4217:USD

xbrli:shares

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

________________________

FORM 8-K

________________________

CURRENT REPORT

Pursuant to Section 13 or 15(d) of The

Securities Exchange Act of 1934

Date of Report (Date of earliest event

reported): September 23,

2026

________________________

Xenetic Biosciences,

Inc.

(Exact name of registrant as specified in charter)

Nevada

001-37937

45-2952962

(State or other jurisdiction

of incorporation)

(Commission

File Number)

(IRS Employer

Identification No.)

945

Concord Street

Framingham, Massachusetts

01701

(Address of principal executive offices)

(Zip Code)

(781) 778-7720

(Registrant’s telephone number, including

area code)

Not Applicable

(Former name or former address, if changed since

last report)

Check the appropriate box below if the

Form 8-K is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see

General Instruction A.2. below):

☐ Written communications

pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☒ Soliciting material

pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement

communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement

communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b)

of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, $0.001 par value per share

XBIO

The

Nasdaq Stock Market

Indicate by check mark whether the registrant

is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities

Exchange Act of 1934 (17 CFR §240.12b-2).

Emerging growth company ☐

If an emerging growth company, indicate by check

mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting

standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 7.01. Regulation FD Disclosure.

On September 23, 2026, Xenetic Biosciences, Inc.

(“Xenetic”) released an updated investor presentation in connection with its pending share exchange transaction with Santersus

AG (“Santersus”) as previously announced on September 16, 2026. Attached as Exhibit 99.1 is a copy of the updated investor

presentation.

The information in this Item 7.01, including Exhibit

99.1 attached hereto, is being furnished, shall not be deemed “filed” for any purpose, and shall not be deemed incorporated

by reference in any filing under the Securities Act, or the Securities Exchange Act of 1934, as amended, except as expressly set forth

by specific reference in such a filing.

Additional Information and Where to Find It

This communication relates to the proposed acquisition

transaction (the “Acquisition”) involving Xenetic and Santersus and may be deemed to be solicitation material in respect of

the Acquisition. In connection with the Acquisition, Xenetic will file with the Securities and Exchange Commission (“SEC”)

a Proxy Statement on Schedule 14A and Registration Statement on Form S-1. Each party may also file other documents regarding the Acquisition

with the SEC. INVESTORS AND SECURITY HOLDERS ARE URGED TO READ CAREFULLY THE PROXY STATEMENT, REGISTRATION STATEMENT ON FORM S-1, AND

OTHER RELEVANT DOCUMENTS FILED OR WILL BE FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS THERETO AND ANY DOCUMENTS INCORPORATED

BY REFERENCE THEREIN, IN THEIR ENTIRETY IF AND WHEN THEY BECOME AVAILABLE BECAUSE THEY CONTAIN OR WILL CONTAIN IMPORTANT INFORMATION ABOUT

THE ACQUISITION, RELATED MATTERS AND THE PARTIES TO THE ACQUISITION. Investors and security holders may obtain a free copy of the Proxy

Statement, the Registration Statement on Form S-1, and other relevant documents (if and when they become available) that are or will be

filed with the SEC for free at the SEC’s website at www.sec.gov. Copies of the documents (when they become available) filed with

the SEC by Xenetic will be available free of charge on Xenetic’s website at http://xeneticbio.com.

Participants in the Solicitation

Xenetic, and its directors and executive officers,

and Santersus, and its directors and officers, may be deemed to be participants in the solicitation of proxies from the stockholders of

Xenetic in connection with the Acquisition under the rules of the SEC. Information about the interests of these directors and executive

officers and other persons who may be deemed to be participants in the solicitation of stockholders of Xenetic in connection with the

Acquisition and a description of their direct and indirect interests, by security holdings or otherwise, will be included in the Proxy

Statement related to the Acquisition, which will be filed with the SEC. Additional information about Xenetic, the directors and executive

officers of Xenetic and their ownership of Xenetic common stock can also be found in its Annual Report on Form 10-K for the year ended

December 31, 2025, as filed with the SEC on March 12, 2026, and amended on April 24, 2026, and its definitive proxy statement, as filed

with the SEC on October 31, 2025, and other documents subsequently filed by Xenetic with the SEC. Free copies of these documents may be

obtained as described above. To the extent holdings of Xenetic securities by its directors or executive officers have changed since the

amounts set forth in such documents, such changes have been or are expected to be reflected on Initial Statements of Beneficial Ownership

on Form 3 or Statements of Beneficial Ownership on Form 4 filed with the SEC. Additional information regarding the identity of potential

participants, and their direct or indirect interests, by security holdings or otherwise, will be included in the Proxy Statement relating

to the Acquisition when it is filed with the SEC.

No Offer or Solicitation

This Current Report on Form 8-K is for informational

purposes only. This communication shall not constitute an offer to subscribe for, buy or sell or the solicitation of an offer to subscribe

for, buy or sell any securities, or a solicitation of any vote or approval, nor shall there be any sale of, or offer to sell or buy, securities

in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities

laws of any such jurisdiction. This communication is for informational purposes only. No offering of securities shall be made, except

by means of a prospectus meeting the requirements of Section 10 of the U.S. Securities Act, and otherwise in accordance with applicable

law.

Forward-Looking Statements

This Current Report on Form 8-K, including the

investor presentation, contains “forward-looking statements” within the meaning of the “safe harbor” provisions

of the Private Securities Litigation Reform Act of 1995, including but not limited to, express or implied statements regarding the structure,

timing and completion of the Acquisition; the combined company’s listing on Nasdaq after closing of the Acquisition; expectations

regarding the ownership structure of the combined company; estimated transaction value and post-closing ownership; the anticipated timing

of closing; the future operations of the combined company; the nature, strategy and focus of the combined company; the development and

commercial potential and potential benefits of NucleoCapture and Xenetic’s DNase technology; anticipated clinical drug development

activities and related timelines, including the expected timing for data and other clinical results; the competitive landscape of the

combined company; the valuations ascribed to each party in connection with the proposed transaction, including the assumptions underlying

such valuations; Net Cash and related adjustments to the Company Valuation; the Exchange Ratio and pro forma capitalization of the combined

company; the expected board composition of the combined company; and other statements that are not historical fact. All statements other

than statements of historical fact contained in this communication are forward-looking statements. These forward-looking statements are

made as of the date they were first issued, and were based on the then-current expectations, estimates, forecasts, and projections, as

well as the beliefs and assumptions of management. Forward-looking statements are subject to a number of risks and uncertainties, many

of which involve factors or circumstances that are beyond Xenetic, Santersus or the combined company’s control. Actual results could

differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to

(i) the risk that the conditions to the closing of the Acquisition are not satisfied, including the failure to timely obtain stockholder

approval for the transaction, if at all; (ii) uncertainties as to the timing of the consummation of the Acquisition and the ability of

each of Xenetic and Santersus to consummate the Acquisition; (iii) risks related to each parties’ ability to manage its operating

expenses and its expenses associated with the Acquisition pending closing; (iv) risks related to the failure or delay in obtaining required

approvals from any governmental or quasi-governmental entity necessary to consummate the Acquisition; (v) the risk that as a result of

adjustments to the exchange ratio, Xenetic stockholders and Santersus stockholders could own more or less of the combined company than

is currently anticipated; (vi) risks related to the market price of Xenetic common stock relative to the value suggested by the exchange

ratio; (vii) unexpected costs, charges or expenses resulting from the Acquisition; (viii) potential adverse reactions or changes to business

relationships resulting from the announcement or completion of the Acquisition; (ix) the uncertainties associated with Xenetic platform

technologies, as well as risks associated with the clinical development and regulatory approval of product candidates, including potential

delays in the commencement, enrollment and completion of clinical trials; (x) risks related to the inability of the combined company to

obtain sufficient additional capital to continue to advance these product candidates and its clinical programs; (xi) uncertainties in

obtaining successful clinical results for product candidates and unexpected costs that may result therefrom; (xii) risks related to the

failure to realize any value from product candidates being developed and anticipated to be developed in light of inherent risks and difficulties

involved in successfully bringing product candidates to market; (xiii) risks associated with the possible failure to realize certain anticipated

benefits of the Acquisition, including with respect to future financial and operating results; (xiv) risks related to the inability of

the combined company to maintain compliance with Nasdaq listing requirements following closing, and the potential need for the combined

company to effect a reverse stock split of Xenetic common stock in order to satisfy Nasdaq listing requirements; (xv) risks related to

the combined company raising additional working capital and financing its business; and (xvi) the other factors discussed under the heading

“Risk Factors” in Xenetic’s most recent Annual Report on Form 10-K and other filings with the SEC, among others. Actual

results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of these

risks and uncertainties. These and other risks and uncertainties are more fully described in filings that Xenetic makes and will make

with the SEC in connection with the Acquisition, including Xenetic’s Proxy Statement described above under “Additional Information

and Where to Find It.” You should not place undue reliance on these forward-looking statements, which are made only as of the date

hereof or as of the dates indicated in the forward-looking statements. Xenetic, Santersus and the combined company expressly disclaims

any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect

any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are

based.

Item 9.01.

Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.

Description

99.1

Investor Presentation, dated September 2026.

104

Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements

of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto

duly authorized.

XENETIC BIOSCIENCES, INC.

By:

/s/ James Parslow

Date: September 23, 2026

Name:

James Parslow

Title:

Interim Chief Executive Officer and Chief Financial Officer

EX-99.1 — INVESTOR PRESENTATION

EX-99.1

Filename: xenetic_ex9901.htm · Sequence: 2

Exhibit 99.1

Advancing NET - Targeted Therapies for Immune - Driven Diseases and Cancer INVESTOR PRESENTATION SEPTEMBER 2026

2 This communication contains “forward - looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995 , including but not limited to, express or implied statements regarding the structure, timing and completion of the proposed transaction ; the combined company’s listing on Nasdaq after closing of the proposed transaction ; expectations regarding the ownership structure of the combined company ; the anticipated timing of closing ; each company’s and the combined company’s expected cash position at the closing of the proposed transaction and cash runway of the combined company ; the future operations of the combined company ; the nature, strategy and focus of the combined company ; the development and commercial potential and potential benefits of NucleoCapture and DNase ; anticipated clinical drug development activities and related timelines, including the expected timing for data and other clinical results ; the competitive landscape of the combined company ; the valuations ascribed to each party in connection with the proposed transaction, including the assumptions underlying such valuations ; Net Cash and related adjustments to the Company Valuation ; the Exchange Ratio and pro forma capitalization of the combined company ; and other statements that are not historical fact . All statements other than statements of historical fact contained in this communication are forward - looking statements . These forward - looking statements are made as of the date they were first issued, and were based on the then - current expectations, estimates, forecasts, and projections, as well as the beliefs and assumptions of management . Forward - looking statements are subject to a number of risks and uncertainties, many of which involve factors or circumstances that are beyond Xenetic Biosciences , Santersus or the combined company’s control . Actual results could differ materially from those stated or implied in forward - looking statements due to a number of factors, including but not limited to (i) the risk that the conditions to the closing of the proposed transaction are not satisfied, including the failure to timely obtain shareholder approval for the transaction, if at all ; (ii) uncertainties as to the timing of the consummation of the proposed transaction and the ability of each of Xenetic Biosciences and Santersus to consummate the proposed transaction ; (iii) risks related to each parties’ ability to manage its operating expenses and its expenses associated with the proposed transaction pending closing ; (iv) risks related to the failure or delay in obtaining required approvals from any governmental or quasi - governmental entity necessary to consummate the proposed transaction ; (v) the risk that as a result of adjustments to the exchange ratio, Xenetic Biosciences shareholders and Santersus stockholders could own more or less of the combined company than is currently anticipated ; (vi) risks related to the market price of Xenetic Biosciences common stock relative to the value suggested by the exchange ratio ; (vii) unexpected costs, charges or expenses resulting from the transaction ; (viii) potential adverse reactions or changes to business relationships resulting from the announcement or completion of the proposed transaction ; (ix) the uncertainties associated with Xenetic Biosciences platform technologies, as well as risks associated with the clinical development and regulatory approval of product candidates, including potential delays in the commencement, enrollment and completion of clinical trials ; (x) risks related to the inability of the combined company to obtain sufficient additional capital to continue to advance these product candidates and its clinical programs ; (xi) uncertainties in obtaining successful clinical results for product candidates and unexpected costs that may result therefrom ; (xii) risks related to the failure to realize any value from product candidates being developed and anticipated to be developed in light of inherent risks and difficulties involved in successfully bringing product candidates to market ; (xiii) risks associated with the possible failure to realize certain anticipated benefits of the proposed transaction, including with respect to future financial and operating results ; (xiv) risks related to the inability of the combined company to maintain compliance with Nasdaq listing requirements following the closing of the proposed transaction, and the potential need for the combined company to effect a reverse stock split in order to satisfy Nasdaq listing requirements ; (xv) risks related to the combined company raising additional working capital and financing its business ; and (xvi) the other factors discussed under the heading “Risk Factors” in Xenetic Biosciences’ most recent Annual Report on Form 10 - K and other filings with the U . S . Securities and Exchange Commission (the “SEC”), among others . Actual results and the timing of events could differ materially from those anticipated in such forward - looking statements as a result of these risks and uncertainties . These and other risks and uncertainties are more fully described in filings that Xenetic Biosciences makes and will make with the SEC in connection with the proposed transaction, including the Proxy Statement described below under “Additional Information and Where to Find It . ” You should not place undue reliance on these forward - looking statements, which are made only as of the date hereof or as of the dates indicated in the forward - looking statements . Xenetic Biosciences , Santersus and the combined company expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward - looking statements contained herein to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based . Xenetic Biosciences and Santersus obtained the industry, market and competitive position data used throughout this presentation from its own internal estimates and research, as well as from industry and general publications, and research, surveys and studies conducted by third parties . Internal estimates are derived from publicly available information released by industry analysts and third - party sources, Xenetic Biosciences and Santersus internal research and its industry experience, and are based on assumptions made by Xenetic Biosciences and Santersus based on such data and its knowledge of the industry and market, which it believes to be reasonable . In addition, while Xenetic Biosciences and Santersus believes the industry, market and competitive position data included in this presentation is reliable and based on reasonable assumptions, Xenetic Biosciences and Santersus has not independently verified any third - party information, and all such data involve risks and uncertainties and are subject to change based on various factors . This presentation contains trademarks, services marks, trade names and copyrights of Xenetic Biosciences and Santersus and other companies, which are the property of their respective owners . The use or display of third parties’ trademarks, service marks, trade name or products in this presentation is not intended to, and does not imply, a relationship with Xenetic Biosciences and Santersus , or an endorsement of sponsorship by Xenetic Biosciences and Santersus . Solely for convenience, the trademarks, service marks and trade names referred to in this presentation may appear with the ®, TM or SM symbols, but such references are not intended to indicate, in any way, that the company will not assert, to the fullest extent under applicable law, their rights or the right of the applicable licensor to these trademarks, service marks and trade name . Additional Information and Where to Find It This communication relates to the proposed acquisition transaction involving Xenetic Biosciences and Santersus and may be deemed to be solicitation material in respect of the proposed transaction. In connection with the proposed transac ti on, Xenetic Biosciences will file with the SEC a proxy statement (“Proxy Statement”) and Registration Statement on Form S - 1 (“Registration Statement”). INVESTORS AND SECURITY HOLDERS ARE URGED TO READ CAREFULLY THE PROXY STATEMENT, REGISTRATION STATEMENT, AND OTHER RELEVANT DOCUMENTS FILED OR WILL BE FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS THERETO AND ANY DOCUME NTS INCORPORATED BY REFERENCE THEREIN, IN THEIR ENTIRETY IF AND WHEN THEY BECOME AVAILABLE BECAUSE THEY CONTAIN OR WILL CONTAIN IMPORTANT INFORMATION ABOUT THE PROPOSED TRANSACTION, RELATED MATTERS AND THE PARTIES TO TH E PROPOSED TRANSACTION. Investors and security holders may obtain a free copy of the Proxy Statement, the Registration Statement, and other relevant doc uments (if and when they become available) that are or will be filed with the SEC for free at the SEC’s website at www.sec.go v. Copies of the documents (when they become available) filed with the SEC by Xenetic Biosciences will be available free of charge on Xene tic Biosciences’ website at http://xeneticbio.com. Participants in the Solicitation Xenetic Biosciences and its directors and executive officers and Santersus and its directors and executive officers, may be deemed to be participants in the solicitation of proxies from the stockholde rs of Xenetic Biosciences in connection with the proposed transaction under the rules of the SEC. Information about the interests of the directors and executive officers of Xenetic Biosciences an d o ther persons who may be deemed to be participants in the solicitation of stockholders of Xenetic Biosciences in connection wi th the proposed transaction and a description of their direct and indirect interests, by security holdings or otherwise, will be included in the Proxy Statement related to the proposed transaction, which will be filed with the SEC. Additional information about Xenetic B io sciences, the directors and executive officers of Xenetic Biosciences and their ownership of Xenetic Biosciences common stock can also be f oun d in its Annual Report on Form 10 - K for the year ended December 31, 2025, as filed with the SEC on March 12, 2026, and its defin itive proxy statement, as filed with the SEC on October 31, 2025, and other documents subsequently filed by Xenetic Biosciences wit h t he SEC. Free copies of these documents may be obtained as described above. To the extent holdings of Xenetic Biosciences secu rit ies by its directors or executive officers have changed since the amounts set forth in such documents, such changes have been or are ex pected to be reflected on Initial Statements of Beneficial Ownership on Form 3 or Statements of Beneficial Ownership on Form 4 f iled with the SEC. Additional information regarding the identity of potential participants, and their direct or indirect interests, by sec urity holdings or otherwise, will be included in the Proxy Statement relating to the Proposed Transaction when it is filed wi th the SEC. No Offer or Solicitation This communication does not constitute an offer to sell or the solicitation of an offer to buy any securities nor a solicitat ion of any vote or approval with respect to the proposed transaction or otherwise. No offering of securities shall be made except b y means of a prospectus meeting the requirements of Section 10 of the U S. Securities Act of 1933, as amended, and otherwise in accordance wi th applicable law. Disclaimer

3 Transaction Valuation and Pro Forma Capitalization Transaction Valuation (4) Ownership in Pro - Forma Company Shares Outstanding / Issued $21 million (3) ~15.0% 2,546,699 (1) Shares outstanding (fully diluted, restricted stock and shares underlying options) Xenetic Biosciences $120 million ~85.0% ≈14,552,566 (2) New Xenetic shares issued at closing (Acquisition Consideration; preferred converts, options assumed at the Exchange Ratio Santersus AG $141 million 100% ≈17,099,265 (2) Total Estimated post - closing ownership per the Share Exchange Agreement dated September 14, 2026, on a fully diluted basis (1) Based upon 2,343,181 shares of common stock outstanding as of July 31, 2026 (2) Illustrative issuance implied by the 85%/15% split; actual number determined by the Exchange Ratio at closing (3) Assumes $0 Net Cash; subject to adjustment pursuant to the Share Exchange Agreement (4) Negotiated valuation agreed by the parties pursuant to the Share Exchange Agreement

4 Transaction Highlights Proposed Transaction is Expected to Close in the Fourth Quarter of 2026 1 Santersus will become a wholly owned subsidiary of Xenetic and will continue as the operating business of the combined company . Combined company is expected to trade on Nasdaq under the ticker symbol “SNTS . ” Combined Company 1. Subject to approval by the stockholders of Xenetic At closing, each outstanding Santersus share will be exchanged for shares of Xenetic common stock . Outstanding unexercised Santersus options will be assumed by Xenetic and converted into options to purchase Xenetic common stock . Definitive Share Exchange Agreement Pre - transaction Santersus shareholders are expected to own approximately 85 % of the combined company and pre - merger Xenetic stockholders are expected to own approximately 15 % of the combined company, subject to adjustment . Ownership

5 Pioneering Breakthrough NET - Targeted Therapies to Transform the Treatment Paradigm of Immune - Driven Diseases and Cancer Positive clinical outcomes with no adverse events across 80+ compassionate use cases in patients with sepsis, autoimmune disease and cancer treated with NucleoCapture® and DNase Extensive IP portfolio through 2038 and potential to extend 20 years with each indication World - leading medical device company invested in Series A NET - Targeting Platforms • Two FDA Breakthrough Device Designations • Lead program targeting potential EU market launch in Q2 2028 • Extracorporeal device pathway offers faster and more capital - efficient route to approval NucleoCapture ® Blood purification device designed to selectively remove circulating NETs DNase Systemic DNase enzyme platform designed to degrade NETs in tissues and blood 1. Grand View Research, “Sepsis Therapeutics Market Size, Share & Trends Analysis Report, 2025 – 2030,” accessed September 1, 2026 ; 2. Mordor Intelligence, Systemic Lupus Erythematosus: Market Share Analysis, Industry Trends & Statistics, Growth Forecasts, 2026 – 2031, May 2026; 3. Grand View Research, Lymphoma Treatment Market Size, Share & Trends Analysis Report, 2025 – 2030 , updated July 2026; 4. Persistence Market Research, Liver Transplantation Market Size, Share, and Growth Forecast, 2026 – 2033 , June 2026. 4 Clinical Stage Programs Targeting Multibillion - Dollar Markets: Investigator - initiated study in Israel in combination with CAR T cells for large B - cell lymphoma initiated by Tel - Aviv Sourasky team, with initial efficacy data expected in Q2 2027 Large B - Cell Lymphoma Liver Transplantation Systemic Lupus Erythematosus Sepsis ~$8.7 Billion 4 ~$1.6 Billion 3 ~$3.4 Billion 2 ~$5.6 Billion 1

6 DNase Blood Purification Device for Circulating NETs Removes NETs directly from circulation via extracorporeal blood purification Targeting high levels of circulating NETs in the blood Pharmacological / Enzymatic for Tissue Based NETs Degrades NETs within solid tissue via enzymatic digestion of the NET DNA backbone Targets NETs embedded in tissue and the tumor microenvironment NucleoCapture ® Definitive Share Exchange Agreement to Create Global Leader in NET - Targeting Therapeutics • Target pathogenic NETs as the common upstream driver of disease • Complementary, not redundant: together addressing NET burden across both circulating and tissue - resident compartments A Shared Mechanistic Basis Two Complementary Technologies. One Target. Neutrophil Extracellular Traps (NETs) Advancing a Pipeline of Multiple Billion - Dollar Opportunities

7 Excessive and Persistent NETs Are Convergent Upstream Driver of Inflammation, Tissue Injury, Immune Dysregulation and Treatment Resistance Neutrophil extracellular traps (NETs) are web - like structures composed of DNA, histones and antimicrobial proteins released by activated neutrophils to trap and neutralize pathogens. Unchecked NET accumulation in blood and tissues triggers a destructiv e c ascade that damages tissue, dysregulates immunity, and accelerates disease progression • Breach endothelial barriers and destroy surrounding tissue • Perpetuate chronic inflammation and drive immune dysregulation • Expose autoantigens and fuel autoimmune attack • Drive immunothrombosis, microvascular obstruction and organ failure • Shield tumor cells from T cell and NK - cell attack • Inactivate cytotoxic T cells and CAR T cells • Capture circulating tumor cells and support metastatic seeding • Reprogram the tumor microenvironment and reactivate dormant tumor cells • Drive resistance to chemotherapy, checkpoint inhibitors and radiotherapy A Validated Driver Across Multiple Serious Disease Areas Critical Illness Autoimmune Disease Transplantation Cancer Cardiovascular Disease Neurodegeneration Kidney Disease Lung Disease Oncology Immune and Inflammatory Disease

8 NucleoCapture® Sepsis in Combination with SoC Systemic Lupus Erythematosus (SLE) in Combination with SoC Liver Graft Perfusion in Combination with OrganOx Metra Device Large B - Cell Lymphoma in Combination with anti - CD - 19 CAR T cells DNase THERAPEUTIC BLOOD PURIFICATION DEVICE PIPELINE SYSTEMIC BIOLOGIC THERAPEUTIC PIPELINE PROGRAM INDICATIONS INITIAL CLINICAL STAGE PIVOTAL CLINICAL TRIAL Advancing Two NET - Targeted Platforms Across Immune - Driven Diseases and Cancer PROGRAM INDICATIONS PRECLINICAL PHASE 1 PHASE 2/3 KEY HIGHLIGHTS • Recruitment in progress • Interim analysis and CE Mark submission: Q4 2027 • EU market launch: Q2 2028 • Start of pivotal study: Q4 2026 • Interim analysis: Q4 2027 • sPMA submission: Q3 2027 • US market launch: Q3 2028 KEY HIGHLIGHTS • Investigator - initiated study in advanced LBCL with CD19 CAR T 1 • Recruitment in progress • Proof - of - concept data: Q2 2027 APPROVAL IND ENABLING 1. Investigator - initiated study being conducted at the Tel Aviv Sourasky University Medical Center in Israel Note: Actual milestones and timeline may vary, as they are based on current expectations, estimates and projections regarding fu ture events. There can be no assurance that the milestones will be achieved within the timeframes indicated, or at all.

9 NucleoCapture ®: FDA - Designated Breakthrough Treatment for Sepsis Proprietary therapeutic blood purification device that physically bind to and remove NETs from blood circulation without affecting neutrophils defensive functions Ongoing pivotal multicenter study, up to 350 patients with sepsis and respiratory failure in EU and US Independent studies in over 3,000 sepsis ICU patients show elevated NET level are associated with increased risk of mortality, septic shock, organ failure and ARDS Designed for rapid deployment in acute and critical - care settings Integrates with standard plasma - separation equipment with no additional hospital capital expenditure Breakthrough Designation from US FDA for Sepsis

10 Demonstrated 100% 7 - Day Survival with Rapid, Repeated Reductions in Circulating NET Levels in Sepsis Patients Reduction in Key Biomarkers Before After Before After Before After Before After Circulating NET Level, ng/mL n=10 Treatment Treatment Treatment Reduction in Circulating Net Levels Circulating NET levels declined after each treatment session and remained below the initial pretreatment level across the treatment course. x 32 NucleoCapture ® treatment sessions in 10 extremely sick sepsis patients x Demonstrated to be safe and well tolerated with no adverse events x Consistently reduced inflammation, organ damage and vasopressor dependence

11 Ongoing Pivotal Multicenter Study for Treatment of Sepsis and Respiratory Failure Study Design Number of Subjects: up to 350 Randomized: 1:1 Treatment: SoC or SoC + NucleoCapture ® Primary Effectiveness Endpoint: Composite outcome evaluated using win ratio methodology: • All - cause mortality through Day 28 / Organ Support - Free Days (OSFD) through Day 28 First time ever FDA agrees on primary composite endpoint of 28 - day mortality and OSFD Anticipated Development Path to Potential Commercialization in US and EU Q4 2027 Q4 2027 EU Regulatory Submission Distribution Agreement Executed Q4 2027 First Interim Analysis (100 Patients) Q2 2028 CE Certificate and EU Market Launch Q2 2029 Enrollment Completed Q2 2029 PMA Submission Q4 2029 PMA Approval and US Market Launch Mortality benefit is the sepsis graveyard Probability of success for the composite endpoint is much higher Concurrent Medicare Coverage via RAPID

12 After the Course of Procedures Before Improvement in Key Indicator Lupus Disease Activity 1 8.0 [4; 12] 17.5 [10; 25] SLEDAI, Me [25th; 75th percentiles] Lupus QoL 76.6 [51.6; 92.2] 57.8 [42.2; 67.2] Physical Health ( ↑ = Improvement) 87.5 [66.7; 91.7] 58.3 [41.7; 70.8] Pain ( ↑ = Improvement) 75.0 [52.1; 85.4] 60.4 [25; 77.1] Emotional health ( ↑ = Improvement) 65.6 [25.0; 78.1] 53.1 [15.6; 71.9] Fatigue Improvement ( ↑ = Improvement) HADS 4 [3; 13] 9 [6; 15] HADS — anxiety 6 [1; 8] 7 [3.5; 10] HADS — depression FACIT - Fatigue 37.5 [20.5; 46.5] 24.5 [14.5; 37] Total FACIT - Fatigue score x No add on immunosuppression x Quick onset of action x Potential to control Type II symptoms NucleoCapture ®: FDA - Designated Breakthrough Treatment for SLE In a retrospective analysis of compassionate use cases (n= 10 ), three treatments were associated with immediate powerful reduction of disease activity, clinical manifestations and broad quality - of - life improvements 54 % Reduction in Disease Activity 1 Median SLEDAI - 2K decreased from 17.5 to 8.0 after three treatments p=0.009 Resolution of Key Clinical Manifestations Vasculitis resolved in 5 of 5 patients Polyarthritis resolved in 3 of 5 patients Fever resolved without additional NSAIDs or steroids Significant Attenuation of Autoimmune and Inflammatory Response Significant reductions in anti - dsDNA, anti - ssDNA and HMGB1 Significant Decrease in Anxiety Trends towards improvement of physical health, pain, emotional health and fatigue Standard of Care Treatment Typically Takes 6 Months to Achieve Comparable Reductions of Disease Activity 1 1. Aringer M, et al. Lupus Sci Med. 2025;12(1):e001336. doi:10.1136/lupus - 2024 - 001336

13 NucleoCapture ®: Restoring Viability in Donor Organs During Ex Vivo Machine Perfusion Liver Revitalization Before After 6 hour Perfusion ~84% Reduction in Circulating NETs 13.54 ± 8.53 to 2.21 ± 0.69 µg/mL From hour 1 to hour 12 of NMP ~67% Reduction in Lactate 5.30 ± 3.56 to 1.75 ± 0.86 mmol/L From hour 1 to hour 12 of NMP , a strategic investor in , acquired for $1.5 billion in 2025 Targeting a 15 - month FDA regulatory pathway through a supplement to the existing OrganOx metra ® PMA Improved viability - associated parameters in 8 discarded human liver grafts meeting ex vivo transplantation criteria Significantly improved graft function and metabolic recovery and reduced inflammation on modelling of transplantation

14 DNase for LBCL: Overcoming Tumor Immune Evasion EGFR CAR T EGFR CAR T plus DNase Metastatic melanoma node; Green and yellow = NETosis area DNase driven survival benefit in mouse model of human lymphoma ( NSG/Raji) Removal of barrier to CAR T cells Deoxyribonuclease I (DNase) is a human endonuclease enzyme responsible for degrading NETs in tissues and blood via enzymatic cleavage of NETs DNA backbone • Investigator - initiated study in 12 patients with LBCL in combination with CAR T ongoing • Designed to be universal CAR T adjunct platform for hematologic and solid tumors acting by reversing tumor induced immunosuppression • Encouraging preclinical data and clinical compassionate use data suggesting clinical efficacy of combination of DNase with CAR T cells • Potential to reduce tumor induced immunosuppression

15 Leadership and Development Team James Ladtkow BSME, MBA Chief Executive Officer Andrew Aswani, MD PhD MRCP FRCA EDIC FFICM Chief Medical Officer and SAB Chairman Elisabeth Barabash, BS, MS Chief Clinical Operations Alexey Stepanov, II, MS, PhD Head of Immunooncology Paul Rowden, BS, MS Head of Quality Marianna Lupi, BS,MS PRRC Dmitry Genkin, MD Chief Scientific Officer Aleksander Zaporoztsev Chief Financial Officer 35+ years in medical device development. Led clinical development and approval of the Spectra Optia therapeutic apheresis system Consultant in Intensive Care Medicine and Anaesthesia . PhD research on circulating cfDNA in shock states 13+ years in clinical operations. Prior industry experience at Pfizer and AstraZeneca Dr. Stepanov develops advanced immuno - oncology therapies, specializing in CAR T cell engineering and solid tumors 27+ years as regulatory partner for medical devices and IVD manufacturers in 30+ countries. 600+ first time approval across FDA 510(k), CE, UKCA, ISO 13485, MDSAP and CMDR International regulatory and clinical affairs executive with extensive Class II and III medical device expertise Founder of the Santersus. inventor of 20+ patents in NETosis and cell - free DNA therapeutics Over 20 years of financial experience, 10 of those years of financial and management expertise in the biopharmaceutical industry

16 Upcoming Value Driving Milestones NucleoCapture ® SLE Program NucleoCapture ® Liver Transplantation Program DNase Large B - Cell Lymphoma Program Q4 2027 Q4 2027 Q4 2027 Q2 2028 First Interim Analysis (100 patients) Exclusive Distribution Agreement EU Regulatory Submission CE Certification and EU Market Launch Q2 2029 Q2 2029 Q4 2029 PMA Submission Enrollment Completed PMA Approval and US Market Launch NucleoCapture ® Sepsis Q1 2027 Q4 2027 Q4 2027 Q4 2028 Q4 2028 Q2 2029 Q4 2029 First Patient In Interim Analysis Exclusive Distribution Agreement Enrollment Completed EU Regulatory Submission CE Certification and EU Market Launch Initiate US Pivotal Study with Potential Partner Q1 2027 Q3 2027 Q3 2028 Exclusive License and Supply Agreement sPMA Submission sPMA Approval and US Market Launch Q2 2027 Q2 2027 Q2 2028 Q3 2028 Enrollment Completed (12 patients) Primary Efficacy Readouts Secondary Efficacy Readouts Initiate US Phase 2 Study with Potential Partner Note: Actual milestones and timeline may vary, as they are based on current expectations, estimates and projections regarding fu ture events. There can be no assurance that the milestones will be achieved within the timeframes indicated, or at all.

17 Positioned to Lead the Emerging Field of NET - Targeted Therapeutics Building an integrated therapeutic portfolio around NETs, an increasingly recognized driver of disease progression across immune - driven diseases and cancer Four prioritized programs spanning sepsis, SLE, liver transplantation and large B - cell lymphoma Lead NucleoCapture ® programs targeting regulatory submissions beginning in 2027 and a potential first EU market launch in 2028 Diversified Pipeline Clear Path Toward Potential Commercialization Two complementary platforms designed to address the issues of excessive or persistent NETs Growing clinical and regulatory momentum Targeting multi - billion - dollar indications with significant unmet needs Multiple key value - driving milestones expected over the next 12 - 24 months

Advancing NET - Targeted Therapies for Immune - Driven Diseases and Cancer Thank you!

Appendix

20 NucleoCapture ® is designed to selectively remove circulating NETs, potentially reducing the autoantigen and inflammatory burden without suppressing immune cells. NucleoCapture ®: Breakthrough Treatment for SLE Excessive NET formation and impaired clearance expose autoantigens, amplify type I interferon signaling and contribute to tissue injury. Rapid, clinically meaningful improvement in disease activity, including a 54% reduction in median SLEDAI - 2K after three treatments. Broad quality - of - life improvements including physical health, pain, fatigue and emotional well - being, with a significant reduction in anxiety. Demonstrated clinical responses without escalation of immunosuppression , including no increase in other immunosuppressive therapies or steroids. Compelling compassionate - use responses across severe autoimmune diseases , including disease control, dialysis independence and improved cardiac function. Self - Reinforcing NET Cycle and Disease Amplification Ⓡ

21 SLE: Significant Reduction in SLE Disease Activity in Retrospective Analysis After 3 NucleoCapture® Treatments Before Indicator 8.0 [4; 12] 17.5 [10; 25] SLEDAI, Me [ 25th; 75th percentiles] 5.2 [3.8 – 5.5] 3.95 [2.4; 5.1] Leukocytes, × 10 9 /µL, Me [25th; 75th percentiles] 16 [12; 18] 25 [18; 40] ESR, mm/h, Me [25th; 75th percentiles] 10.225 [7.3; 15.95] 12.9 [9; 17.5] IgG, g/L, Me [25th; 75th percentiles] 342.2 [54.1; 684] 592.5 [42; 784] Anti - dsDNA, IU/mL, Me [25th; 75th percentiles] 249.4 [123; 422.8] 392 [297.1; 584.1] Anti - ssDNA, IU/mL, Me [25th; 75th percentiles] 0.465 [0.195; 3.47] 5.59 [0.89; 10.5] HMGB1, ng/mL, Me [25th; 75th percentiles] Standard of Care Treatment Typically Takes 6 Months to Achieve Comparable Reductions of Disease Activity 1 54% Reduction in Disease Activity • Median SLEDAI - 2K decreased from 17.5 to 8.0 after three treatments p=0.009 Resolution of Key Clinical Manifestations • Vasculitis resolved in 5 of 5 patients Polyarthritis resolved in 3 of 5 patients • Fever resolved without additional NSAIDs or steroids Significant Autoimmune and Inflammatory Response • Significant reductions in anti - dsDNA, anti - ssDNA and HMGB1 Leukocyte Levels Trended Toward Normalization • Median leukocyte count increased from 3.95 to 5.2 × 10⁹/ Lp =0.078 1. Aringer M, et al. Lupus Sci Med. 2025;12(1):e001336. doi:10.1136/lupus - 2024 - 001336

22 SLE: Quality - of - Life Improvements in Patients with SLE Flares After The Course of Procedures Before Improvement in Key Indicator Lupus QoL 76.6 [51.6; 92.2] 57.8 [42.2; 67.2] Physical Health ( ↑ = Improvement) 87.5 [66.7; 91.7] 58.3 [41.7; 70.8] Pain ( ↑ = Improvement) 54.2 [16.7; 83.3] 58.3 [25; 79.2] Planning ( ↓ = Improvement) 56.3 [25; 75] 65.5 [25; 93.8] Intimate Relationships ( ↓ = Improvement) 62.5 [37.5; 79.2] 54.2 [20.8; 75] Burden to Others ( ↑ = Improvement) 75.0 [52.1; 85.4] 60.4 [25; 77.1] Emotional Health ( ↑ = Improvement) 62.5 [54.2; 85] 75.8 [56.7; 91.3] Body Image ( ↓ = Improvement) 65.6 [25.0; 78.1] 53.1 [15.6; 71.9] Fatigue Improvement ( ↑ = Improvement) HADS 4 [3; 13] 9 [6; 15] HADS — Anxiety 6 [1; 8] 7 [3.5; 10] HADS — Depression FACIT - Fatigue 37.5 [20.5; 46.5] 24.5 [14.5; 37] Total FACIT - Fatigue Score In a retrospective analysis, patients (n=10) reported broad quality - of - life improvements, with a statistically significant reduction in anxiety. Positive clinical outcomes in 20+ compassionate use cases in patients with neurolupus, ANCA vasculitis, antiphospholipid syndrome, juvenile polyarteritis nodosa.

23 Upcoming Pivotal Multicenter Study in EU and Hong Kong for Treatment of SLE Study Design Number of Subjects: up to 110 with active SLE, SLEDAI - 2K score ≥ 8 Randomized: 1:1 Treatment: SoC or SoC + NucleoCapture ® Primary Effectiveness Endpoint: Proportion of participants achieving a SLE Responder Index 4 (SRI - 4) response at D30 Secondary Effectiveness Endpoint: • Control of Type II symptoms • Reduction of corticosteroid usage Anticipated Development Path to Potential Commercialization in US and EU Q4 2028 Q4 2029 Q1 2027 First Patient In Q4 2027 Q4 2027 Q4 2028 Q3 2029 Interim Analysis Distribution Agreement Executed Enrollment Completed EU Regulatory Submission CE Certification and EU Market Launch Initiate US Pivotal Study with Potential Partner Anticipated Development Path to Potential Commercialization in US and EU

24 Demonstrated Sustained cfDNA Reduction and Metabolic Recovery in Discarded Human Livers Eight discarded extended - criteria donor human livers underwent 12 hours of OrganOx metra ® NMP with NucleoCapture , followed by six hours of whole - blood reperfusion modeling ~84% Reduction in Circulating NETs 13.54 ± 8.53 to 2.21 ± 0.69 µg/mL From hour 1 to hour 12 of NMP ~67% Reduction in Lactate 5.30 ± 3.56 to 1.75 ± 0.86 mmol/L Significant lactate clearance during NMP, p=0.011 Significant reduction in circulating neutrophils during the first 60 minutes of whole - blood reperfusion During NMP, NucleoCapture ® is designed to remove NETs, helping prevent microcirculatory collapse and inflammation in the graft. Path to Potential FDA Approved Integration with OrganOx Metra Q3 2027 Q3 2028 sPMA Submission sPMA Approval and US Market Launch Q1 2027 Exclusive License and Supply Agreement

25 DNase Improves In Vivo Efficacy of CAR T Cells Mice treated by CAR19 T cells in combination with DNase demonstrate improved survival and primary tumor clearance in leukemia and lymphoma models with improved CAR19 T cells expansion and persistence DNase survival benefit in mouse model of human lymphoma ( NSG/Raji) Enhanced CAR19 T cells Expansion and Persistence In vivo tracking of CAR19 T cells in mouse model of human lymphoma ( NSG/Raji)

26 Investigator - Initiated Study in Large B - Cell Lymphoma Anticipated Development Path Q2 2027 Q2 2028 Q3 2028 Primary Efficacy Readouts Secondary Efficacy Readouts Initiate US Phase 2 Study with Potential Partner Q2 2027 Completion of Enrollment Study Design CRR (complete response rate) at 1 month post CAR T infusion • ORR at 1 and 3 months after CART • PFS at 12 months post CAR T cells • Duration of response (DOR) • Overall survival (OS) at 12 months post CAR T cells • Frequency and severity of CAR T related adverse events (CRS ICANS, TLS) Primary Effectiveness Endpoint Secondary Effectiveness Endpoint Number of Subjects Treatment 12 subjects with stable/progressive LBCL prior to lymphodepletion CAR T cells ( tisagenlecleucel , axicabtagene ciloleucel or lisocabtagene maraleucel ) in combination with DNase

GRAPHIC

Filename: image_027.jpg · Sequence: 6

Binary file (227930 bytes)

Download image_027.jpg

GRAPHIC

Filename: image_028.jpg · Sequence: 7

Binary file (465013 bytes)

Download image_028.jpg

GRAPHIC

Filename: image_029.jpg · Sequence: 8

Binary file (113493 bytes)

Download image_029.jpg

GRAPHIC

Filename: image_030.jpg · Sequence: 9

Binary file (156397 bytes)

Download image_030.jpg

GRAPHIC

Filename: image_031.jpg · Sequence: 10

Binary file (233964 bytes)

Download image_031.jpg

GRAPHIC

Filename: image_032.jpg · Sequence: 11

Binary file (172505 bytes)

Download image_032.jpg

GRAPHIC

Filename: image_033.jpg · Sequence: 12

Binary file (213941 bytes)

Download image_033.jpg

GRAPHIC

Filename: image_034.jpg · Sequence: 13

Binary file (158341 bytes)

Download image_034.jpg

GRAPHIC

Filename: image_035.jpg · Sequence: 14

Binary file (158046 bytes)

Download image_035.jpg

GRAPHIC

Filename: image_036.jpg · Sequence: 15

Binary file (161648 bytes)

Download image_036.jpg

GRAPHIC

Filename: image_037.jpg · Sequence: 16

Binary file (146157 bytes)

Download image_037.jpg

GRAPHIC

Filename: image_038.jpg · Sequence: 17

Binary file (212266 bytes)

Download image_038.jpg

GRAPHIC

Filename: image_039.jpg · Sequence: 18

Binary file (177555 bytes)

Download image_039.jpg

GRAPHIC

Filename: image_040.jpg · Sequence: 19

Binary file (171298 bytes)

Download image_040.jpg

GRAPHIC

Filename: image_041.jpg · Sequence: 20

Binary file (192789 bytes)

Download image_041.jpg

GRAPHIC

Filename: image_042.jpg · Sequence: 21

Binary file (178579 bytes)

Download image_042.jpg

GRAPHIC

Filename: image_043.jpg · Sequence: 22

Binary file (156662 bytes)

Download image_043.jpg

GRAPHIC

Filename: image_044.jpg · Sequence: 23

Binary file (225319 bytes)

Download image_044.jpg

GRAPHIC

Filename: image_045.jpg · Sequence: 24

Binary file (64012 bytes)

Download image_045.jpg

GRAPHIC

Filename: image_046.jpg · Sequence: 25

Binary file (190430 bytes)

Download image_046.jpg

GRAPHIC

Filename: image_047.jpg · Sequence: 26

Binary file (192820 bytes)

Download image_047.jpg

GRAPHIC

Filename: image_048.jpg · Sequence: 27

Binary file (159578 bytes)

Download image_048.jpg

GRAPHIC

Filename: image_049.jpg · Sequence: 28

Binary file (156686 bytes)

Download image_049.jpg

GRAPHIC

Filename: image_050.jpg · Sequence: 29

Binary file (177785 bytes)

Download image_050.jpg

GRAPHIC

Filename: image_051.jpg · Sequence: 30

Binary file (168902 bytes)

Download image_051.jpg

GRAPHIC

Filename: image_052.jpg · Sequence: 31

Binary file (147104 bytes)

Download image_052.jpg

XML — IDEA: XBRL DOCUMENT

XML

Filename: R1.htm · Sequence: 33

v3.26.3

Cover

Sep. 23, 2026

Cover [Abstract]

Document Type

8-K

Amendment Flag

false

Document Period End Date

Sep. 23, 2026

Entity File Number

001-37937

Entity Registrant Name

Xenetic Biosciences,

Inc.

Entity Central Index Key

0001534525

Entity Tax Identification Number

45-2952962

Entity Incorporation, State or Country Code

Entity Address, Address Line One

945

Concord Street

Entity Address, City or Town

Framingham

Entity Address, State or Province

Entity Address, Postal Zip Code

01701

City Area Code

(781)

Local Phone Number

778-7720

Written Communications

false

Soliciting Material

true

Pre-commencement Tender Offer

false

Pre-commencement Issuer Tender Offer

false

Title of 12(b) Security

Common Stock, $0.001 par value per share

Trading Symbol

XBIO

Security Exchange Name

NASDAQ

Entity Emerging Growth Company

false

- Definition

Boolean flag that is true when the XBRL content amends previously-filed or accepted submission.

+ References

No definition available.

+ Details

Name:

dei_AmendmentFlag

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

Period Type:

duration

- Definition

Area code of city

+ References

No definition available.

+ Details

Name:

dei_CityAreaCode

Namespace Prefix:

dei_

Data Type:

xbrli:normalizedStringItemType

Balance Type:

Period Type:

duration

- Definition

Cover page.

+ References

No definition available.

+ Details

Name:

dei_CoverAbstract

Namespace Prefix:

dei_

Data Type:

xbrli:stringItemType

Balance Type:

Period Type:

duration

- Definition

For the EDGAR submission types of Form 8-K: the date of the report, the date of the earliest event reported; for the EDGAR submission types of Form N-1A: the filing date; for all other submission types: the end of the reporting or transition period. The format of the date is YYYY-MM-DD.

+ References

No definition available.

+ Details

Name:

dei_DocumentPeriodEndDate

Namespace Prefix:

dei_

Data Type:

xbrli:dateItemType

Balance Type:

Period Type:

duration

- Definition

The type of document being provided (such as 10-K, 10-Q, 485BPOS, etc). The document type is limited to the same value as the supporting SEC submission type, or the word 'Other'.

+ References

No definition available.

+ Details

Name:

dei_DocumentType

Namespace Prefix:

dei_

Data Type:

dei:submissionTypeItemType

Balance Type:

Period Type:

duration

- Definition

Address Line 1 such as Attn, Building Name, Street Name

+ References

No definition available.

+ Details

Name:

dei_EntityAddressAddressLine1

Namespace Prefix:

dei_

Data Type:

xbrli:normalizedStringItemType

Balance Type:

Period Type:

duration

- Definition

Name of the City or Town

+ References

No definition available.

+ Details

Name:

dei_EntityAddressCityOrTown

Namespace Prefix:

dei_

Data Type:

xbrli:normalizedStringItemType

Balance Type:

Period Type:

duration

- Definition

Code for the postal or zip code

+ References

No definition available.

+ Details

Name:

dei_EntityAddressPostalZipCode

Namespace Prefix:

dei_

Data Type:

xbrli:normalizedStringItemType

Balance Type:

Period Type:

duration

- Definition

Name of the state or province.

+ References

No definition available.

+ Details

Name:

dei_EntityAddressStateOrProvince

Namespace Prefix:

dei_

Data Type:

dei:stateOrProvinceItemType

Balance Type:

Period Type:

duration

- Definition

A unique 10-digit SEC-issued value to identify entities that have filed disclosures with the SEC. It is commonly abbreviated as CIK.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection b-2

+ Details

Name:

dei_EntityCentralIndexKey

Namespace Prefix:

dei_

Data Type:

dei:centralIndexKeyItemType

Balance Type:

Period Type:

duration

- Definition

Indicate if registrant meets the emerging growth company criteria.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection b-2

+ Details

Name:

dei_EntityEmergingGrowthCompany

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

Period Type:

duration

- Definition

Commission file number. The field allows up to 17 characters. The prefix may contain 1-3 digits, the sequence number may contain 1-8 digits, the optional suffix may contain 1-4 characters, and the fields are separated with a hyphen.

+ References

No definition available.

+ Details

Name:

dei_EntityFileNumber

Namespace Prefix:

dei_

Data Type:

dei:fileNumberItemType

Balance Type:

Period Type:

duration

- Definition

Two-character EDGAR code representing the state or country of incorporation.

+ References

No definition available.

+ Details

Name:

dei_EntityIncorporationStateCountryCode

Namespace Prefix:

dei_

Data Type:

dei:edgarStateCountryItemType

Balance Type:

Period Type:

duration

- Definition

The exact name of the entity filing the report as specified in its charter, which is required by forms filed with the SEC.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection b-2

+ Details

Name:

dei_EntityRegistrantName

Namespace Prefix:

dei_

Data Type:

xbrli:normalizedStringItemType

Balance Type:

Period Type:

duration

- Definition

The Tax Identification Number (TIN), also known as an Employer Identification Number (EIN), is a unique 9-digit value assigned by the IRS.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection b-2

+ Details

Name:

dei_EntityTaxIdentificationNumber

Namespace Prefix:

dei_

Data Type:

dei:employerIdItemType

Balance Type:

Period Type:

duration

- Definition

Local phone number for entity.

+ References

No definition available.

+ Details

Name:

dei_LocalPhoneNumber

Namespace Prefix:

dei_

Data Type:

xbrli:normalizedStringItemType

Balance Type:

Period Type:

duration

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 13e

-Subsection 4c

+ Details

Name:

dei_PreCommencementIssuerTenderOffer

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

Period Type:

duration

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 14d

-Subsection 2b

+ Details

Name:

dei_PreCommencementTenderOffer

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

Period Type:

duration

- Definition

Title of a 12(b) registered security.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection b

+ Details

Name:

dei_Security12bTitle

Namespace Prefix:

dei_

Data Type:

dei:securityTitleItemType

Balance Type:

Period Type:

duration

- Definition

Name of the Exchange on which a security is registered.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection d1-1

+ Details

Name:

dei_SecurityExchangeName

Namespace Prefix:

dei_

Data Type:

dei:edgarExchangeCodeItemType

Balance Type:

Period Type:

duration

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 14a

-Subsection 12

+ Details

Name:

dei_SolicitingMaterial

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

Period Type:

duration

- Definition

Trading symbol of an instrument as listed on an exchange.

+ References

No definition available.

+ Details

Name:

dei_TradingSymbol

Namespace Prefix:

dei_

Data Type:

dei:tradingSymbolItemType

Balance Type:

Period Type:

duration

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Securities Act

-Number 230

-Section 425

+ Details

Name:

dei_WrittenCommunications

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

Period Type:

duration