Assessment of the Global Intraoperative Radiation Therapy Market 2026-2031, Featuring Profiles of Siemens Healthineers, Elekta, Carl Zeiss Meditec, IntraOp Medical, iCAD and More

Assessment of the Global Intraoperative Radiation Therapy Market 2026-2031, Featuring Profiles of Siemens Healthineers, Elekta, Carl Zeiss Meditec, IntraOp Medical, iCAD and More Dublin, Sept. 07, 2026 (GLOBE NEWSWIRE) -- The "Intraoperative Radiation Therapy - Market Share Analysis, Industry Trends & Statistics, Growth Forecasts (2026-2031)" has been added to ResearchAndMarkets.com's offering.

The global intraoperative radiation therapy market is estimated at USD 132.93 million in 2026, up from USD 123.41 million in 2025. The market is projected to reach USD 192.79 million by 2031, expanding at a compound annual growth rate of 7.72% from 2026 to 2031. Growth is being supported by rising cancer incidence, technological advances in radiation delivery and increasing demand for shorter, targeted treatment courses.

Rising Cancer Burden Accelerates Demand for Intraoperative Radiation Therapy

Global cancer incidence is projected to reach 24 million new cases by 2030, placing additional pressure on radiotherapy infrastructure. Capacity constraints are particularly acute in emerging economies. India, for example, has 521 radiotherapy centers serving more than 1.3 million annual cancer cases, contributing to treatment delays and limited access.

Intraoperative radiation therapy enables radiation to be delivered during surgery, reducing reliance on prolonged post-operative treatment schedules. By consolidating treatment into a single procedure for selected patients, healthcare providers can improve facility throughput and reserve conventional radiotherapy capacity for complex cases. The approach is also gaining attention in ageing populations, where comorbidities and travel requirements can make multi-week treatment courses difficult.

Technology Advances Improve Precision and Clinical Workflows

Innovation in imaging, surgical robotics, treatment planning and radiation delivery is strengthening the clinical potential of intraoperative radiation therapy. New imaging platforms can shorten acquisition times while improving tumor and lesion visualization. Emerging FLASH radiation protocols, which deliver radiation at ultra-high dose rates, are also being evaluated for their potential to limit damage to surrounding healthy tissue and reduce treatment times.

Artificial intelligence is increasingly being applied to surgical margin assessment and treatment planning. Certain AI models have achieved 84% accuracy in predicting positive margins during breast-conserving surgery, potentially lowering the risk of repeat procedures. Miniaturized accelerators, lighter shielding systems and battery-operated technologies may further expand access, particularly in hospitals with limited infrastructure.

Workforce Shortages Remain a Key Market Constraint

Despite favorable market conditions, shortages of trained radiation therapists, medical dosimetrists and multidisciplinary clinical teams continue to restrict adoption. Radiation therapist vacancy rates reached 10.7% in 2022, while medical dosimetrist shortages are expected to persist through 2035.

Intraoperative radiation therapy requires close, real-time coordination among surgeons, radiation oncologists, physicists and therapists. This expertise is often concentrated in major tertiary care centers. Smaller hospitals may also find it difficult to maintain dedicated teams when patient volumes are limited, creating regional disparities in access. Continued investment in specialized education, certification and hands-on clinical training will be essential to support market expansion.

Electron IORT Maintains Market Leadership

Electron IORT accounted for 59.45% of the intraoperative radiation therapy market in 2025, supported by its established use in breast cancer treatment and the availability of mobile accelerator workflows. Existing hospital supply chains for applicators, quality-assurance tools and related equipment also reinforce adoption.

Intraoperative brachytherapy is forecast to grow at an 8.21% CAGR through 2031. High-definition afterloaders and real-time dosimetry software are improving dose conformity in irregular surgical cavities. Photon-based technologies and alpha-particle seed systems remain a smaller segment but are attracting interest for applications including recurrent glioblastoma. Purchasing decisions increasingly reflect procedure duration, shielding requirements, treatment location and staff familiarity.

Services and Integrated Platforms Gain Strategic Importance

Capital equipment generated 66.60% of market revenue in 2025, driven by sales and replacement cycles for accelerators, imaging consoles and treatment systems. Hospitals in mature markets typically refresh equipment every seven to eight years as software, imaging and AI capabilities evolve.

Services are expected to record an 8.29% CAGR through 2031 as providers seek packages combining physics support, remote quality assurance, maintenance and staff certification. Software subscriptions and predictive maintenance analytics now account for an increasing share of recurring revenue. Integrated platforms that connect pathology, imaging and dosimetry data are also helping hospitals reduce fragmented workflows and improve clinical coordination.

Regional Intraoperative Radiation Therapy Market Outlook

North America held 42.10% of the global market in 2025, supported by established reimbursement pathways, bundled-payment programs and investment by integrated healthcare networks. Mobile systems that rotate among hospital campuses are helping providers improve utilization and returns on equipment investments.

Europe continues to demonstrate steady adoption, although reimbursement varies among countries. Clinical guidelines in Germany and Italy support IORT for selected breast cancer patients, while UK pilot studies have reported savings of approximately GBP 2,300 per case, largely through reduced transportation and treatment-related costs. Scandinavian markets also show strong utilization because single-procedure treatment can benefit patients living across widely dispersed regions.

Asia-Pacific is projected to grow at an 8.71% CAGR through 2031, making it one of the fastest-growing regional markets. Government-backed radiotherapy programs, ageing populations and investment in oncology infrastructure are supporting adoption in China, Japan, Taiwan and India. Mobile electron systems used in Indian rural outreach programs have reduced average patient travel distances by 53% compared with city-based treatment facilities. However, shortages of trained oncology professionals remain a significant barrier across the region.

South America, the Middle East and Africa represent emerging opportunities as governments and private providers invest in hybrid operating rooms and oncology modernization. Public-private partnerships, equipment leasing and refurbished systems are lowering some entry barriers, although currency volatility, import tariffs and workforce limitations continue to affect near-term adoption. Over the forecast period, unmet cancer-treatment needs and demographic change are expected to support long-term growth across these developing markets.

Key Topics Covered

1 Introduction

1.1 Study Assumptions & Market Definition

1.2 Scope of the Study

2 Research Methodology

3 Executive Summary

4 Market Landscape

4.1 Market Overview

4.2 Market Drivers

4.2.1 Growing global prevalence of cancer

4.2.2 Advancements in cancer-therapy technologies

4.2.3 Advantages of IORT over prolonged external-beam courses

4.2.4 Outpatient-bundled payment models incentivising single-dose IORT

4.2.5 Miniaturisation of mobile electron accelerators for low-resource ORs

4.2.6 AI-guided intra-op imaging improving margin assessment & uptake

4.3 Market Restraints

4.3.1 Shortage of trained multidisciplinary IORT teams

4.3.2 Clinical preference for conventional fractionated radiotherapy

4.3.3 Limited long-term outcome data beyond breast indications

4.3.4 High shielding / OR-retro-fit capex for mobile CT-compatible units

4.4 Value / Supply-Chain Analysis

4.5 Regulatory Landscape

4.6 Technological Outlook

4.7 Porter's Five Forces Analysis

4.7.1 Threat of New Entrants

4.7.2 Bargaining Power of Buyers

4.7.3 Bargaining Power of Suppliers

4.7.4 Threat of Substitutes

4.7.5 Intensity of Competitive Rivalry

5 Market Size & Growth Forecasts (Value, USD)

5.1 By Method

5.1.1 Electron IORT

5.1.2 Intraoperative Brachytherapy

5.1.3 Other Methods

5.2 By Products and Services

5.2.1 Products

5.2.1.1 Systems and Accelerators

5.2.1.2 Applicators & Afterloaders

5.2.1.3 Treatment Planning Systems

5.2.1.4 Accessories

5.2.2 Services

5.3 By Application

5.3.1 Breast Cancer

5.3.2 Brain Tumor

5.3.3 Gastro-intestinal Cancer

5.3.4 Head and Neck Cancer

5.3.5 Other Applications

5.4 By End User

5.4.1 Hospitals

5.4.2 Specilaty Clinics

5.4.3 Others

5.5 By Geography

5.5.1 North America

5.5.1.1 United States

5.5.1.2 Canada

5.5.1.3 Mexico

5.5.2 Europe

5.5.2.1 Germany

5.5.2.2 United Kingdom

5.5.2.3 France

5.5.2.4 Italy

5.5.2.5 Spain

5.5.2.6 Rest of Europe

5.5.3 Asia-Pacific

5.5.3.1 China

5.5.3.2 Japan

5.5.3.3 India

5.5.3.4 Australia

5.5.3.5 South Korea

5.5.3.6 Rest of Asia-Pacific

5.5.4 Middle East and Africa

5.5.4.1 GCC

5.5.4.2 South Africa

5.5.4.3 Rest of Middle East and Africa

5.5.5 South America

5.5.5.1 Brazil

5.5.5.2 Argentina

5.5.5.3 Rest of South America

6 Competitive Landscape

6.1 Market Concentration

6.2 Market Share Analysis

6.3 Company Profiles (includes Global level Overview, Market level overview, Core Segments, Financials as available, Strategic Information, Market Rank/Share for key companies, Products & Services, and Recent Developments)

6.3.1 Siemens Healthineers (Varian Medical Systems)

6.3.2 Elekta AB

6.3.3 Carl Zeiss Meditec AG

6.3.4 IntraOp Medical Corporation

6.3.5 iCAD Inc.

6.3.6 Ariane Medical Systems Ltd

6.3.7 Eckert & Ziegler

6.3.8 GMV Innovating Solutions

6.3.9 Sensus Healthcare Inc.

6.3.10 Sordina IORT Technologies

6.3.11 Isoray Inc.

6.3.12 Accuray Incorporated

6.3.13 Ion Beam Applications S.A. (IBA)

6.3.14 Brainlab AG

6.3.15 Zap Surgical Systems Inc.

6.3.16 medPhoton GmbH

6.3.17 Surgiceye GmbH

6.3.18 ViewRay Inc.

7 Market Opportunities & Future Outlook

7.1 White-space & Unmet-need Assessment

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