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Epilepsy Market Set to Grow During the Forecast Period (2026-2036) as Novel Antiseizure Therapies Gain Momentum | DelveInsight

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XENE Xenon Pharmaceuticals' drug Azetukalner (XEN1101) is highlighted as a novel, potent, and selective therapy for epilepsy, showing strong potential in clinical development and expected to contribute to market growth. BHVN Biohaven Pharmaceuticals' BHV-7000 is a potent and selective KCNQ2 potassium channel activator in Phase II/III trials for epilepsy, showing potential as a well-tolerated treatment for refractory epilepsy. STOK Stoke Therapeutics is developing Zorevunersen (STK-001), an emerging therapy for epilepsy, contributing to the pipeline of novel treatments expected to drive market growth. NBIX Neurocrine Biosciences is mentioned as a company developing NBI-'355 for epilepsy, contributing to the pipeline of emerging therapies. NVS Novartis is mentioned for its marketed therapy Everolimus (AFINITOR DISPERZ) for epilepsy, indicating its presence in the current treatment landscape. UCB UCB is listed as a key company in the epilepsy market, with mentions in reports for partial and chronic focal epilepsy, indicating its involvement. VRTX Vertex Pharmaceuticals is listed as a key company in the partial epilepsy market, indicating its involvement in the broader epilepsy therapeutic area. GSK GlaxoSmithKline is listed as a key company in the chronic focal epilepsy market, indicating its involvement in the broader epilepsy therapeutic area. SAN Sanofi is listed as a key company in the chronic focal epilepsy market, indicating its involvement in the broader epilepsy therapeutic area. MDT Medtronic is listed as a key company in the chronic focal epilepsy market, indicating its involvement in the broader epilepsy therapeutic area. IBIO IAMA Therapeutics is listed as a key company in the drug-resistant epilepsy market, indicating its involvement in the broader epilepsy therapeutic area. BMB Bright Minds Bio is listed as a key company in the drug-resistant epilepsy market, indicating its involvement in the broader epilepsy therapeutic area. OVID Ovid Therapeutics is listed as a key company in the Dravet syndrome market, indicating its involvement in the broader epilepsy therapeutic area. PTC PTC Therapeutics is listed as a key company in the Dravet syndrome market, indicating its involvement in the broader epilepsy therapeutic area.

Epilepsy Market Set to Grow During the Forecast Period (2026-2036) as Novel Antiseizure Therapies Gain Momentum | DelveInsight The epilepsy market is expected to grow due to an increase in disease prevalence and the expected launch of emerging therapies, including Azetukalner (XEN1101; Xenon Pharmaceuticals), ABS-1230 (Actio Biosciences), BHV-7000 (Biohaven Pharmaceuticals), Relutrigine (PRAX-562; Praxis Precision Medicines), Zorevunersen (STK-001; Stoke Therapeutics), and others during the forecast period.

LAS VEGAS, Oct. 27, 2026 /PRNewswire/ -- Recently published Epilepsy Market Insights report includes a comprehensive understanding of current treatment practices, epilepsy emerging drugs, market share of individual therapies, and current and forecasted market size from 2022 to 2036, segmented into leading markets [the United States, the EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan].

Epilepsy Market Summary

Discover the future of the epilepsy diagnosis & treatment market @ https://www.delveinsight.com/report-store/epilepsy-market

Key Factors Driving the Growth of the Epilepsy Market

Shikha Bhardwaj, Associate Consultant of Forecasting & Analytics at DelveInsight, said that the epilepsy pipeline shows strong potential to address treatment gaps, focusing on Kv7 potassium channel agonists, GABAA receptor agonists, CH24H inhibitors, positive allosteric modulators of GABAA receptors, and other innovative therapies.

Epilepsy Market Analysis

Epilepsy Competitive Landscape

Some of the epilepsy drugs under development include Azetukalner (XEN1101; Xenon Pharmaceuticals), ABS-1230 (Actio Biosciences), BHV-7000 (Biohaven Pharmaceuticals), Relutrigine (PRAX-562; Praxis Precision Medicines), Zorevunersen (STK-001; Stoke Therapeutics), ETX101 (Encoded Therapeutics), Bexicaserin (LP352; Lundbeck), SPN-817 (Supernus Pharmaceuticals), NRTX-1001 (Neurona Therapeutics), NBI-'355 (Neurocrine Biosciences), and others.

Xenon Pharmaceuticals' Azetukalner (XEN1101) is a novel, potent, and selective orally administered KCNQ2/3 (Kv7.2/7.3) potassium channel opener being developed for the treatment of epilepsy, including focal onset seizures and primary generalized tonic–clonic seizures (PGTCS). As a neuronal Kv7 voltage-gated potassium channel opener, it is designed to stabilize neuronal activity, regulate action potential burst firing, and reduce neuronal hyperexcitability associated with seizures.

Actio Biosciences' ABS-1230 is an anticipated first-in-class, orally administered, selective small-molecule KCNT1 inhibitor being developed for the treatment of KCNT1-related epilepsy. In preclinical studies, ABS-1230 demonstrated inhibitory activity against all tested pathogenic KCNT1 mutations, supporting its potential to address a broad population of patients with KCNT1-related epilepsy. The therapy may also offer the convenience of oral, at-home treatment. The initial Phase Ia study is being conducted under a U.S. FDA Investigational New Drug (IND) application, with Ethics Committee approval for the study in Australia. ABS-1230 has received U.S. FDA Fast Track, Rare Pediatric Disease (RPD), and Orphan Drug (ODD) designations.

Biohaven Pharmaceuticals' BHV-7000 is a potent and selective KCNQ2 potassium channel activator under development for epilepsy and other neurological disorders. By modulating neuronal excitability, it is designed to address the underlying mechanisms contributing to seizure activity. Currently being evaluated in Phase II/III clinical trials, BHV-7000 has demonstrated potential as a well-tolerated treatment option for patients with refractory epilepsy.

The anticipated launch of these emerging therapies are poised to transform the epilepsy market landscape in the coming years. As these cutting-edge therapies continue to mature and gain regulatory approval, they are expected to reshape the epilepsy market landscape, offering new standards of care and unlocking opportunities for medical innovation and economic growth.

Discover more about the new epilepsy drugs 2026 @ Epilepsy Drugs

Recent Developments in the Epilepsy Market

Epilepsy Epidemiology Segmentation

The epilepsy epidemiology section provides insights into the historical and current epilepsy patient pool and forecasted trends for the leading markets. The US had the highest cases of epilepsy, of which nearly 67% of the cases were focal epileptic seizures, 31% were generalized epileptic seizures, while 2% of the cases were other determined or undetermined epileptic seizures.

The epilepsy treatment market report proffers epidemiological analysis for the study period 2022–2036 in the leading markets, segmented into:

Epilepsy Market Report Metrics

Details

Study Period

2022–2036

Coverage

7MM [The United States, the EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan].

Epilepsy Market Size in 2025

USD 10.5 Billion

Key Epilepsy Companies

Xenon Pharmaceuticals, Actio Biosciences, Biohaven Pharmaceuticals, Praxis Precision Medicines, Stoke Therapeutics, Encoded Therapeutics, Lundbeck, Supernus Pharmaceuticals, Neurona Therapeutics, Neurocrine Biosciences, Neurelis, Novartis, UCB, and others

Key Epilepsy Therapies

Azetukalner (XEN1101), ABS-1230, BHV-7000, Relutrigine (PRAX-562), Zorevunersen (STK-001), ETX101, Bexicaserin (LP352), SPN-817, NRTX-1001, NBI-'355, VALTOCO, AFINITOR DISPERZ, BRIVIACT, and others

Scope of the Epilepsy Market Report

Download the report to understand the anti-epilepsy drugs market @ Epilepsy Clinical Trials

Table of Contents

1

Epilepsy Market Key Insights

2

Epilepsy Market Report Introduction

3

Executive Summary of Epilepsy

4

Key Events of Epilepsy

5

Epilepsy Epidemiology and Market Forecast Methodology

6

Epilepsy Market Overview at a Glance

6.1

Clinical Landscape Analysis (by Phase, RoA, and Molecule Type)

6.2

Market Share (%) Distribution of Epilepsy by Therapies in 2025

6.3

Market Share (%) Distribution of Epilepsy by Therapies in 2036

7

Disease Background and Overview of Epilepsy

7.1

Introduction

7.2

Signs and Symptoms

7.3

Causes

7.4

Diagnosis

8

Treatment and Management

9

Epidemiology and Patient Population of Epilepsy in the 7MM

9.1

Key Findings

9.2

Assumptions and Rationale

9.3

Total Diagnosed Prevalent Cases of Epilepsy in the 7MM

9.4

The United States

9.4.1

Total Diagnosed Prevalent Cases of Epilepsy in the US

9.4.2

Gender-specific Diagnosed Prevalent Cases of Epilepsy in the US

9.4.3

Diagnosed Prevalent Cases of Epilepsy Based on Seizure Type in the US

9.4.4

Diagnosed Cases of Other Types of Epilepsies and Associated Diseases in the US

9.5

EU4 and the UK

9.6

Japan

10

Patient Journey of Epilepsy

11

Marketed Therapies of Epilepsy

11.1

Marketed Competitive Landscape of Epilepsy

11.2

VALTOCO: Neurelis

11.2.1

Product Description

11.2.2

Regulatory Milestones

11.2.3

Other Developmental Activities

11.2.4

Summary of Pivotal Trials

11.2.5

Clinical Development

11.2.5.1

Clinical Trials Information

11.2.6

Safety and Efficacy

11.2.7

Analyst Views

11.3

Everolimus (AFINITOR DISPERZ): Novartis

List to be continued in the report…

12

Emerging Therapies of Epilepsy

12.1

Emerging Competitive Landscape of Epilepsy

12.2

Azetukalner (XEN1101): Xenon Pharmaceuticals

12.2.1

Product Description

12.2.2

Other Developmental Activities

12.2.3

Clinical Development

12.2.3.1

Clinical Trials Information

12.2.4

Safety and Efficacy

12.2.5

Analyst Views

12.3

ABS-1230: Actio Biosciences

12.4

BHV-7000: Biohaven Pharmaceuticals

List to be continued in the report…

13

Epilepsy Market: 7MM Analysis

13.1

Key Findings

13.2

Key Epilepsy Market Forecast Assumptions

13.3

Epilepsy Market Outlook

13.4

Conjoint Analysis

13.5

Total Market Size of Epilepsy in the 7MM

13.6

Total Market Size of Epilepsy by Therapies in the 7MM

13.7

The United States Epilepsy Market Size

13.7.1

Total Market Size of Epilepsy in the United States

13.7.2

Market Size of Epilepsy by Therapies in the United States

13.8

EU4 and the UK Epilepsy Market Size

13.9

Japan Epilepsy Market Size

14

KOL Views of Epilepsy

15

SWOT Analysis of Epilepsy

16

Unmet Needs of Epilepsy

17

Market Access and Reimbursement of Epilepsy

17.1

The United States

17.2

In EU4 and the UK

17.3

Japan

17.4

Summary and Comparison of Market Access and Pricing Policy Developments in 2025

17.5

Market Access and Reimbursement of Epilepsy

18

Bibliography

19

Epilepsy Market Report Methodology

Types of Epilepsy

DelveInsight possesses extensive expertise in the neurological disorders market, supported by a dedicated and experienced team specializing in this therapeutic area. The company has recently published a series of epidemiology-based market reports covering various forms of epilepsy, including Partial Epilepsy, Chronic Focal Epilepsy, Drug-Resistant Epilepsy, Dravet Syndrome, and others. These reports provide an in-depth assessment of the current treatment landscape, emerging therapies, individual treatment market shares, and historical and forecasted market sizes from 2022 to 2036 across the 7MM, comprising the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan.

Partial Epilepsy Market

Partial Epilepsy Market Insights, Epidemiology, and Market Forecast – 2036 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key partial epilepsy companies including Vertex Pharmaceuticals, Supernus Pharmaceuticals, Xenon Pharmaceuticals, UCB Pharmaceuticals, and others.

Chronic Focal Epilepsy Market

Chronic Focal Epilepsy Market Insights, Epidemiology, and Market Forecast – 2036 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key chronic focal epilepsy companies, including GlaxoSmithKline, Sanofi, UCB Pharma, Eisai, Medtronic, and others.

Drug-Resistant Epilepsy Market

Drug-resistant Epilepsy Market Insights, Epidemiology, and Market Forecast – 2036 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key drug-resistant epilepsy companies, including Neurona Therapeutics, IAMA Therapeutics, Bright Minds Bio, and others.

Dravet Syndrome Market

Dravet Syndrome Market Insights, Epidemiology, and Market Forecast – 2036 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key Dravet syndrome companies, including Biocodex, GW Pharmaceuticals, Zogenix, Ovid Therapeutics, PTC Therapeutics, and others.

About DelveInsight

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SOURCE DelveInsight Business Research, LLP