Form 8-K

8-K — Pluri Inc.

Accession: 0001213900-26-035110

Filed: 2026-03-27

Period: 2026-03-25

CIK: 0001158780

SIC: 2836 (BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES))

Item: Entry into a Material Definitive Agreement

Item: Unregistered Sales of Equity Securities

Item: Financial Statements and Exhibits

Documents

8-K — ea0283653-8k_pluri.htm (Primary)

EX-4.1 — FORM OF WARRANT (ea028365301ex4-1.htm)

EX-10.1 — SECURITIES PURCHASE AGREEMENT (ea028365301ex10-1.htm)

XML — IDEA: XBRL DOCUMENT (R1.htm)

8-K — CURRENT REPORT

8-K (Primary)

Filename: ea0283653-8k_pluri.htm · Sequence: 1

false

0001158780

2026-03-25

iso4217:USD

xbrli:shares

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UNITED

STATES

SECURITIES

AND EXCHANGE COMMISSION

WASHINGTON,

DC 20549

FORM

8-K

CURRENT

REPORT PURSUANT

TO SECTION 13 OR 15(d) OF THE

SECURITIES

EXCHANGE ACT OF 1934

Date

of report (Date of earliest event reported): March 27, 2026 (March 25, 2026)

PLURI

INC.

(Exact

Name of Registrant as Specified in Its Charter)

Nevada

001-31392

98-0351734

(State

or Other Jurisdiction

of Incorporation)

(Commission

File Number)

(IRS

Employer

Identification No.)

MATAM

Advanced Technology Park

Building

No. 5

Haifa,

Israel

3508409

(Address

of Principal Executive Offices)

(Zip

Code)

011

972 74 710 7171

(Registrant’s

telephone number, including area code)

(Former

name or former address, if changed since last report)

Check

the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under

any of the following provisions:

☐

Written communications pursuant to Rule 425 under the

Securities Act (17 CFR 230.425)

☐

Soliciting material pursuant to Rule 14a-12 under the

Exchange Act (17 CFR 240.14a-12)

☐

Pre-commencement communications pursuant to Rule 14d-2(b)

under the Exchange Act (17 CFR 240.14d-2(b))

☐

Pre-commencement communications pursuant to Rule 13e-4(c)

under the Exchange Act (17 CFR 240.13e-4(c))

Securities

registered pursuant to Section 12(b) of the Act:

Title

of each class

Trading

Symbol(s)

Name

of each exchange on which registered

Common Shares, par value

$0.00001 per share

PLUR

The Nasdaq Capital Market

Indicate

by check mark whether the registrant is an emerging growth company as defined in as defined in Rule 405 of the Securities Act of 1933

(§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging

growth company ☐

an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying

with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 1.01

Entry into a Material Definitive Agreement.

March 25, 2026, Pluri Inc. (the “Company”) entered into a Securities Purchase Agreement (the “Securities Purchase Agreement”),

effective as of March 24, 2026, with Chutzpah Holdings LP (the “Purchaser”), a limited partnership beneficially owned by

Mr. Alexandre Weinstein, a non-U.S. investor and an existing shareholder and director of the Company (“Mr. Weinstein”), relating

to a private placement offering (the “Offering”) of: (i) 625,000 common shares, par value $0.00001 per share (the “Common

Shares”) of the Company, and (ii) warrants (the “Common Warrants”) to purchase up to 625,000 Common Shares. The combined

purchase price for each Common Share and Common Warrant is $4.00. The Common Warrants will be exercisable immediately at an exercise

price of $4.25 per share and will be exercisable until the expiration of the eighteen-month anniversary following closing of the Offering.

The Common Warrants contain customary anti-dilution provisions and are subject to a 35% beneficial ownership limitation. The Securities

Purchase Agreement contains customary representations, warranties and indemnification obligations of the parties.

The

gross proceeds to the Company from the Offering are expected to be approximately $2.5 million. The Company intends to use the proceeds

from the Offering for working capital and general corporate purposes. The entirety of the Offering is expected to close on or about the

end of April 2026, subject to the satisfaction of customary closing conditions.

The

securities issued with respect to the Offering are exempt from the registration requirements of the Securities Act of 1933, as amended

(the “Securities Act”), pursuant to Section 4(a)(2) of the Securities Act and/or Rule 903 of Regulation S promulgated thereunder.

The securities have not been registered under the Securities Act and may not be sold in the United States absent registration or an exemption

from registration.

This

Current Report on Form 8-K shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of

these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification

under the securities laws of any such state or jurisdiction.

The

foregoing descriptions of the Securities Purchase Agreement and the Common Warrants are qualified in their entirety by reference to the

full text of the Securities Purchase Agreement and the form of Common Warrants, copies of which are filed as Exhibits 10.1 and 4.1, respectively.

Item

3.02 Unregistered Sales of Equity Securities.

The

response to this item is included in Item 1.01, Entry into a Material Definitive Agreement, and is incorporated herein in its entirety.

Item

9.01 Financial Statements and Exhibits.

(d)

Exhibits

Exhibit

No.

Description

4.1

Form of Warrant

10.1

Securities Purchase Agreement

104

Cover Page Interactive Data File (embedded within the

Inline XBRL document)

Safe Harbor

Statement

This

Current Report on Form 8-K contains express or implied forward-looking statements within the Private Securities Litigation Reform Act

of 1995 and other U.S. Federal securities laws. For example, the Company is using forward-looking statements when it discusses the expected

closing of the Offering, the receipt of the proceeds from the Offering and the intended use of the proceeds from the Offering. These

forward-looking statements and their implications are based on the current expectations of the management of the Company only and are

subject to a number of factors and uncertainties that could cause actual results to differ materially from those described in the forward-looking

statements. The following factors, among others, could cause actual results to differ materially from those described in the forward-looking

statements about the Company: the conditions to the closing of the Offering may not be met; changes in technology and market requirements;

the Company may encounter delays or obstacles in launching and/or successfully completing its clinical trials, if necessary; the Company’s

products may not be approved by regulatory agencies; the Company’s technology may not be validated as it progresses further and

its methods may not be accepted by the scientific community; the Company may be unable to retain or attract key employees whose knowledge

is essential to the development of its products; unforeseen scientific difficulties may develop with the Company’s processes; the

Company’s products may wind up being more expensive than it anticipates; results in the laboratory may not translate to equally

good results in real clinical settings; the Company’s patents may not be sufficient; the Company’s products may harm recipients

or consumers; changes in legislation with an adverse impact; inability to timely develop and introduce new technologies, products and

applications; and loss of market share and pressure on pricing resulting from competition, which could cause the actual results or performance

of the Company to differ materially from those contemplated in such forward-looking statements. Except as otherwise required by law,

the Company undertakes no obligation to publicly release any revisions to these forward-looking statements to reflect events or circumstances

after the date hereof or to reflect the occurrence of unanticipated events. For a more detailed description of the risks and uncertainties

affecting the Company, reference is made to the Company’s reports filed from time to time with the Securities and Exchange Commission.

SIGNATURES

Pursuant

to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by

the undersigned hereunto duly authorized.

PLURI INC.

Date: March 27, 2026

By:

/s/

Liat Zalts

Name:

Liat Zalts

Title:

Chief Financial Officer

EX-4.1 — FORM OF WARRANT

EX-4.1

Filename: ea028365301ex4-1.htm · Sequence: 2

Exhibit 4.1

NEITHER THIS SECURITY NOR THE SECURITIES INTO

WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY

STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”),

AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT

TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE

WITH APPLICABLE STATE SECURITIES LAWS. THIS SECURITY AND THE SECURITIES ISSUABLE UPON EXERCISE OF THIS SECURITY MAY BE PLEDGED IN CONNECTION

WITH A BONA FIDE MARGIN ACCOUNT WITH A REGISTERED BROKER-DEALER OR OTHER LOAN SECURED BY SUCH SECURITIES. THE HOLDER OF THIS COMMON SHARES

PURCHASE WARRANT BY ITS ACCEPTANCE HEREOF, AGREES THAT IT WILL NOT SELL, TRANSFER, ASSIGN, PLEDGE OR HYPOTHECATE THIS PURCHASE WARRANT

EXCEPT AS HEREIN PROVIDED.

COMMON SHARES PURCHASE WARRANT

PLURI INC.

Warrant Shares: 625,000

Issue Date: ___________, 2026

THIS COMMON SHARES

PURCHASE WARRANT (the “Warrant”) certifies that, for value received, Chutzpah Holdings LP, registered

office 337 WINSTON ROAD OAKVILLE Ontario (CA-ON), L6L 4W6 CANADA, or its assigns (the “Holder”) is entitled,

upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after ___________,

2026 (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on the date that is the eighteen

(18) month anniversary of the Initial Exercise Date, but not thereafter (the “Termination Date”), to subscribe

for and purchase from Pluri Inc., a Nevada corporation (the “Company”), up to 625,000 shares (as subject

to adjustment hereunder, the “Warrant Shares”) of Common Shares. The purchase price of one Common Share under this

Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

Section 1. Definitions.

Capitalized terms used and not otherwise defined herein shall have the meanings set forth in that certain Securities Purchase Agreement

(the “Agreement”), dated March 24, 2026, between the Company and the Holder. In addition to the terms

defined elsewhere in this Warrant, the following terms have the meanings indicated in this Section 1:

“Affiliate”

means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control

with a Person, as such terms are used in and construed under Rule 405 under the Securities Act.

“Business Day”

means any day except any Friday, Saturday, any Sunday, any day which is a federal legal holiday in the United States, Israel or any day

on which banking institutions in the State of New York are authorized or required by law or other governmental action to close.

“Commission”

means the United States Securities and Exchange Commission.

“Common Shares Equivalents”

means any securities of the Company or its subsidiaries which would entitle the holder thereof to acquire at any time Common Shares, including,

without limitation, any debt, preferred shares, right, option, warrant or other instrument that is at any time convertible into or exercisable

or exchangeable for, or otherwise entitles the holder thereof to receive, Common Shares.

“Exchange Act”

means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder.

“Person”

means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability company,

joint stock company, government (or an agency or subdivision thereof) or other entity of any kind.

“Securities Act”

means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.

“Trading Day”

means a day on which the Common Shares are traded on a Trading Market.

“Trading Market”

means any of the following markets or exchanges on which the Common Shares are listed or quoted for trading on the date in question: the

NYSE, the NYSE MKT, the Nasdaq Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market, the New York Stock Exchange

or the OTC Bulletin Board (or any successors to any of the foregoing.

“Transfer Agent”

means Equiniti Trust Company, LLC, the current transfer agent of the Company, with a mailing

address of 55 Challenger Road, Floor 2, Ridgefield Park, NJ 07660, and any successor transfer

agent of the Company.

Section 2. Exercise.

a) Exercise

of Warrants. Exercise of the purchase rights represented by this Warrant may be made, in whole or in part, at any time or times on

or after the Initial Exercise Date and on or before the Termination Date by delivery to the Company (or such other office or agency of

the Company as it may designate by notice in writing to the registered Holder at the address of the Holder appearing on the books of

the Company) of a duly executed facsimile copy (or e-mail attachment) of the Notice of Exercise in the form annexed hereto. Within the

earlier of (i) three (3) Trading Days and (ii) the number of Trading Days comprising the Standard Settlement Period (as defined in Section

2(d)(i) herein) following the date of exercise as aforesaid, the Holder shall deliver the aggregate Exercise Price for the shares specified

in the applicable Notice of Exercise by wire transfer drawn on a United States or Israeli bank. No ink-original Notice of Exercise shall

be required, nor shall any medallion guarantee (or other type of guarantee or notarization) of any Notice of Exercise form be required.

Notwithstanding anything herein to the contrary, the Holder shall not be required to physically surrender this Warrant to the Company

until the Holder has purchased all of the Warrant Shares available hereunder and the Warrant has been exercised in full, in which case,

the Holder shall surrender this Warrant to the Company for cancellation within five (5) Trading Days of the date the final Notice of

Exercise is delivered to the Company. Partial exercises of this Warrant resulting in purchases of a portion of the total number of Warrant

Shares available hereunder shall have the effect of lowering the outstanding number of Warrant Shares purchasable hereunder in an amount

equal to the applicable number of Warrant Shares purchased. The Holder and the Company shall maintain records showing the number of Warrant

Shares purchased and the date of such purchases. The Company shall deliver any objection to any Notice of Exercise within one (1) Business

Day of receipt of such notice. The Holder and any assignee, by acceptance of this Warrant, acknowledge and agree that, by reason of the

provisions of this paragraph, following the purchase of a portion of the Warrant Shares hereunder, the number of Warrant Shares available

for purchase hereunder at any given time may be less than the amount stated on the face hereof.

b) Exercise

Price. The exercise price per share of the Common Shares under this Warrant shall be $4.25 per Warrant Share, subject

to adjustment hereunder (the “Exercise Price”).

c) Mechanics

of Exercise.

i. Delivery

of Warrant Shares Upon Exercise. The Company shall cause the Warrant Shares purchased hereunder to be transmitted by the Transfer

Agent to the Holder by crediting the account of the Holder’s or its designee’s balance account with The Depository Trust

Company through its Deposit or Withdrawal at Custodian system (“DWAC”) if the Company is then a participant in such

system and there is an effective registration statement permitting the issuance of the Warrant Shares to or resale of the Warrant Shares

by Holder, and otherwise by physical delivery of a certificate, registered in the Company’s share register in the name of the Holder

or its designee, for the number of Warrant Shares to which the Holder is entitled pursuant to such exercise to the address specified

by the Holder in the Notice of Exercise by the date that is the earlier of (i) one (1) Trading Day and (ii) the number of Trading Days

comprising the Standard Settlement Period after the delivery to the Company of the Notice of Exercise (such date, the “Warrant

Share Delivery Date”). Upon delivery of the Notice of Exercise, the Holder shall be deemed for all corporate purposes to have

become the holder of record of the Warrant Shares with respect to which this Warrant has been exercised, irrespective of the date of

delivery of the Warrant Shares, provided that payment of the aggregate Exercise Price is received within the earlier of (i) three (3)

Trading Days and (ii) the number of Trading Days comprising the Standard Settlement Period following delivery of the Notice of Exercise.

As used herein, “Standard Settlement Period” means the standard settlement period, expressed in a number of Trading Days,

on the Company’s primary Trading Market with respect to the Common Shares as in effect on the date of delivery of the Notice of

Exercise.

ii. Delivery

of New Warrants Upon Exercise. If this Warrant shall have been exercised in part, the Company shall, at the request of a Holder and

upon surrender of this Warrant certificate, at the time of delivery of the Warrant Shares, deliver to the Holder a new Warrant evidencing

the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant, which new Warrant shall in all other respects

be identical with this Warrant.

iii. Rescission

Rights. If the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares pursuant to Section 2(d)(i)

by the Warrant Share Delivery Date, then the Holder will have the right to rescind such exercise in addition to any other action that

the Holder may exercise pursuant to applicable law.

iv. No Fractional

Shares or Scrip. No fractional shares or scrip representing fractional shares shall be issued upon the exercise of this Warrant.

As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company shall, at its

election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the Exercise

Price or round up to the next whole share.

v. Charges,

Taxes and Expenses. Issuance of Warrant Shares shall be made without charge to the Holder for any issue or transfer tax or other incidental

expense in respect of the issuance of such Warrant Shares, all of which taxes and expenses shall be paid by the Company, and such Warrant

Shares shall only be issued in the name of the Holder (or, if Written Consent has been obtained pursuant to Section 4(a), in the name

of the approved assignee ); provided, however, that in the event that Warrant Shares are to be issued in a name other than

the name of the Holder, subject to receipt of Written Consent, this Warrant when surrendered for exercise shall be accompanied by the

Assignment Form attached hereto duly executed by the Holder and the Company may require, as a condition thereto, the payment of a sum

sufficient to reimburse it for any transfer tax incidental thereto. The Company shall pay all Transfer Agent fees required for same-day

processing of any Notice of Exercise and all fees to the Depository Trust Company (or another established clearing corporation performing

similar functions) required for same-day electronic delivery of the Warrant Shares.

vi. Closing

of Books. The Company will not close its shareholder books or records in any manner which prevents the timely exercise of this Warrant,

pursuant to the terms hereof, unless otherwise required by law.

d) Holder’s

Exercise Limitations. The Company shall not effect any exercise of this Warrant, and the Holder shall not have the right to exercise

any portion of this Warrant, pursuant to Section 2 or otherwise, to the extent that after giving effect to such issuance after exercise

as set forth on the applicable Notice of Exercise, the Holder (together with (i) the Holder’s Affiliates, (ii) any other Persons

acting as a group together with the Holder or any of the Holder’s Affiliates, and (iii) any other Persons whose beneficial ownership

of Common Shares would or could be aggregated with the Holder’s for the purposes of Section 13(d) (such Persons, “Attribution

Parties”)), would beneficially own in excess of the Beneficial Ownership Limitation (as defined below). For purposes of the foregoing

sentence, the number of Common Shares beneficially owned by the Holder and its Affiliates and Attribution Parties shall include the number

of Warrant Shares issuable upon exercise of this Warrant with respect to which such determination is being made, but shall exclude the

number of Warrant Shares which would be issuable upon (i) exercise of the remaining, nonexercised portion of this Warrant beneficially

owned by the Holder or any of its Affiliates or Attribution Parties and (ii) exercise or conversion of the unexercised or nonconverted

portion of any other securities of the Company (including, without limitation, any other Common Shares Equivalents) subject to a limitation

on conversion or exercise analogous to the limitation contained herein beneficially owned by the Holder or any of its Affiliates or Attribution

Parties. Except as set forth in the preceding sentence, for purposes of this Section 2(d), beneficial ownership shall be calculated in

accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder, it being acknowledged by the Holder

that the Company is not representing to the Holder that such calculation is in compliance with Section 13(d) of the Exchange Act and the

Holder is solely responsible for any schedules required to be filed in accordance therewith. To the extent that the limitation contained

in this Section 2(d) applies, the determination of whether this Warrant is exercisable (in relation to other securities owned by the Holder

together with any Affiliates and Attribution Parties) and of which portion of this Warrant is exercisable shall be in the sole discretion

of the Holder, and the submission of a Notice of Exercise shall be deemed to be the Holder’s determination of whether this Warrant

is exercisable (in relation to other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which

portion of this Warrant is exercisable, in each case subject to the Beneficial Ownership Limitation, and the Company shall have no obligation

to verify or confirm the accuracy of such determination and shall have no liability for exercises of the Warrant that are not in compliance

with the Beneficial Ownership Limitation, except to the extent the Holder relies on the number of outstanding Common Shares that was provided

by the Company. In addition, a determination as to any group status as contemplated above shall be determined in accordance with Section

13(d) of the Exchange Act and the rules and regulations promulgated thereunder, and the Company shall have no obligation to verify or

confirm the accuracy of such determination and shall have no liability for exercises of the Warrant that are not in compliance with the

Beneficial Ownership Limitation. For purposes of this Section 2(d), in determining the number of outstanding Common Shares, a Holder may

rely on the number of outstanding Common Shares as reflected in (A) the Company’s most recent periodic or annual report filed with

the Securities and Exchange Commission (the “Commission”), as the case may be, (B) a more recent public announcement by the

Company or (C) a more recent written notice by the Company or the Transfer Agent setting forth the number of Common Shares outstanding.

Upon the written or oral request of a Holder, the Company shall within one Trading Day confirm orally and in writing to the Holder the

number of Common Shares then outstanding. In any case, the number of outstanding Common Shares shall be determined after giving effect

to the conversion or exercise of securities of the Company, including this Warrant, by the Holder or its Affiliates or Attribution Parties

since the date as of which such number of outstanding Common Shares was reported. The “Beneficial Ownership Limitation” shall

be 35% of the number of Common Shares outstanding immediately after giving effect to the issuance of the Warrant Shares issuable upon

exercise of this Warrant. The Holder, upon notice to the Company, may increase or decrease the Beneficial Ownership Limitation provisions

of this Section 2(d), provided that the Beneficial Ownership Limitation in no event exceeds 35% of the number of Common Shares outstanding

immediately after giving effect to the issuance of Warrant Shares upon exercise of this Warrant held by the Holder and the provisions

of this Section 2(d) shall continue to apply. Any increase in the Beneficial Ownership Limitation will not be effective until the 61st

day after such notice is delivered to the Company. The provisions of this paragraph shall be construed and implemented in a manner otherwise

than in strict conformity with the terms of this Section 2(d) to correct this paragraph (or any portion hereof) which may be defective

or inconsistent with the intended Beneficial Ownership Limitation herein contained or to make changes or supplements necessary or desirable

to properly give effect to such limitation. The limitations contained in this paragraph apply to a successor holder of this Warrant. If

the Warrant is unexercisable solely because of the Holder’s Beneficial Ownership Limitation, no alternate consideration is owing

to the Holder.

Section 3.

Certain Adjustments.

a) Share Dividends

and Splits. If the Company, at any time while this Warrant is outstanding: (i) pays a share dividend or otherwise makes a distribution

or distributions on shares of its Common Shares or any other equity or equity equivalent securities payable in Common Shares (which,

for avoidance of doubt, shall not include Common Shares issued by the Company upon exercise of this Warrant), (ii) subdivides outstanding

Common Shares into a larger number of shares, (iii) combines (including by way of reverse share split) outstanding Common Shares into

a smaller number of shares, or (iv) issues by reclassification of Common Shares, any shares of capital stock of the Company, then in

each case the Exercise Price shall be multiplied by a fraction of which the numerator shall be the number of Common Shares (excluding

treasury shares, if any) outstanding immediately before such event and of which the denominator shall be the number Common Shares outstanding

immediately after such event, and the number of shares issuable upon exercise of this Warrant shall be proportionately adjusted such

that the aggregate Exercise Price of this Warrant shall remain unchanged. Any adjustment made pursuant to this Section 3(a) shall become

effective immediately after the record date for the determination of shareholders entitled to receive such dividend or distribution and

shall become effective immediately after the effective date in the case of a subdivision, combination or re-classification.

b) Subsequent

Rights Offerings. In addition to any adjustments pursuant to Section 3(a) above, if at any time the Company grants, issues or sells

any Common Shares Equivalents or rights to purchase share, warrants, securities or other property pro rata to the record holders of any

class of Common Shares (the “Purchase Rights”), then the Holder will be entitled to acquire, upon the terms applicable

to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had held the number of Common

Shares acquirable upon complete exercise of this Warrant, subject to the Beneficial Ownership Limitation, immediately before the date

on which a record is taken for the grant, issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which

the record holders of Common Shares are to be determined for the grant, issue or sale of such Purchase Rights (provided, however, to

the extent that the Holder’s right to participate in any such Purchase Right would result in the Holder exceeding the Beneficial

Ownership Limitation, then the Holder shall not be entitled to participate in such Purchase Right to such extent (or beneficial ownership

of such Common Shares as a result of such Purchase Right to such extent) and such Purchase Right to such extent shall be held in abeyance

for the Holder until the such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation).

c) Pro

Rata Distributions. During such time as this Warrant is outstanding, if the Company shall declare or make any dividend or other distribution

of its assets (or rights to acquire its assets) to holders of Common Shares, by way of return of capital or otherwise (including, without

limitation, any distribution of cash, shares or other securities, property or options by way of a dividend, spin off, reclassification,

corporate rearrangement, scheme of arrangement or other similar transaction) (a “Distribution”), at any time after

the issuance of this Warrant, then, in each such case, the Holder shall be entitled to participate in such Distribution to the same extent

that the Holder would have participated therein if the Holder had held the number Common Shares acquirable upon complete exercise of this

Warrant (without regard to any limitations on exercise hereof, but subject to the Beneficial Ownership Limitation) immediately before

the date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders of

Common Shares are to be determined for the participation in such Distribution. To the extent that this Warrant has not been partially

or completely exercised at the time of such Distribution, such portion of the Distribution shall be held in abeyance for the benefit of

the Holder until the Holder has exercised this Warrant.

d) Fundamental

Transaction. If, at any time while this Warrant is outstanding, (i) the Company, directly or indirectly, in one or more related transactions

effects any merger or consolidation of the Company with or into another Person, (ii) the Company, directly or indirectly, effects any

sale, lease, license, assignment, transfer, conveyance or other disposition of all or substantially all of its assets in one or a series

of related transactions, (iii) any, direct or indirect, purchase offer, tender offer or exchange offer (whether by the Company or another

Person) is completed pursuant to which holders of Common Shares are permitted to sell, tender or exchange their shares for other securities,

cash or property and has been accepted by the holders of more than 50% of the outstanding Common Shares, (iv) the Company, directly or

indirectly, in one or more related transactions effects any reclassification, reorganization or recapitalization of the Common Shares

or any compulsory share exchange pursuant to which the Common Shares is effectively converted into or exchanged for other securities,

cash or property, or (v) the Company, directly or indirectly, in one or more related transactions consummates a stock or share purchase

agreement or other business combination (including, without limitation, a reorganization, recapitalization, spin-off or scheme of arrangement)

with another Person or group of Persons whereby such other Person or group acquires more than 50% of the outstanding Common Shares (not

including any Common Shares held by the other Person or other Persons making or party to, or associated or affiliated with the other

Persons making or party to, such stock or share purchase agreement or other business combination) (each a “Fundamental Transaction”),

then, upon any subsequent exercise of this Warrant, the Holder shall have the right to receive, for each Warrant Share that would have

been issuable upon such exercise immediately prior to the occurrence of such Fundamental Transaction, at the option of the Holder (without

regard to any limitation in Section 2(d) on the exercise of this Warrant), the number of Common Shares of the successor or acquiring

corporation or of the Company, if it is the surviving corporation, and any additional consideration (the “Alternate Consideration”)

receivable as a result of such Fundamental Transaction by a holder of the number of Common Shares for which this Warrant is exercisable

immediately prior to such Fundamental Transaction (without regard to any limitation in Section 2(d) on the exercise of this Warrant).

For purposes of any such exercise, the determination of the Exercise Price shall be appropriately adjusted to apply to such Alternate

Consideration based on the amount of Alternate Consideration issuable in respect of one Common Share in such Fundamental Transaction,

and the Company shall apportion the Exercise Price among the Alternate Consideration in a reasonable manner reflecting the relative value

of any different components of the Alternate Consideration. If holders of Common Shares are given any choice as to the securities, cash

or property to be received in a Fundamental Transaction, then the Holder shall be given the same choice as to the Alternate Consideration

it receives upon any exercise of this Warrant following such Fundamental Transaction. The Company shall cause any successor entity in

a Fundamental Transaction in which the Company is not the survivor (the “Successor Entity”) to assume in writing all

of the obligations of the Company under this Warrant and the other Transaction Documents in accordance with the provisions of this Section

3(d) pursuant to written agreements in form and substance reasonably satisfactory to the Holder and approved by the Holder (without unreasonable

delay) prior to such Fundamental Transaction and shall, at the option of the Holder, deliver to the Holder in exchange for this Warrant

a security of the Successor Entity evidenced by a written instrument substantially similar in form and substance to this Warrant which

is exercisable for a corresponding number of shares of capital stock of such Successor Entity (or its parent entity) equivalent to the

Common Shares acquirable and receivable upon exercise of this Warrant (without regard to any limitations on the exercise of this Warrant)

prior to such Fundamental Transaction, and with an exercise price which applies the exercise price hereunder to such shares of capital

stock (but taking into account the relative value of the Common Shares pursuant to such Fundamental Transaction and the value of such

shares of capital stock, such number of shares of capital stock and such exercise price being for the purpose of protecting the economic

value of this Warrant immediately prior to the consummation of such Fundamental Transaction), and which is reasonably satisfactory in

form and substance to the Holder. Upon the occurrence of any such Fundamental Transaction, the Successor Entity shall succeed to, and

be substituted for (so that from and after the date of such Fundamental Transaction, the provisions of this Warrant and the other Transaction

Documents referring to the “Company” shall refer instead to the Successor Entity), and may exercise every right and power

of the Company and shall assume all of the obligations of the Company under this Warrant and the other Transaction Documents with the

same effect as if such Successor Entity had been named as the Company herein.

e) Calculations.

All calculations under this Section 3 shall be made to the nearest cent or the nearest 1/100th of a share, as the case may be. For purposes

of this Section 3, the number of Common Shares deemed to be issued and outstanding as of a given date shall be the sum of the number of

Common Shares (excluding treasury shares, if any) issued and outstanding.

f) Notice

to Holder.

i. Adjustment

to Exercise Price. Whenever the Exercise Price is adjusted pursuant to any provision of this Section 3, unless the Company otherwise

publishes any such adjustment via a public announcement, the Company shall promptly deliver to the Holder by facsimile or email a notice

setting forth the Exercise Price after such adjustment and any resulting adjustment to the number of Warrant Shares and setting forth

a brief statement of the facts requiring such adjustment.

ii. Notice

to Allow Exercise by Holder. If (A) the Company shall declare a dividend (or any other distribution in whatever form) on the Common

Shares, (B) the Company shall declare a special nonrecurring cash dividend on or a redemption of Common Shares, (C) the Company shall

authorize the granting to all holders of Common Shares rights or warrants to subscribe for or purchase any shares of capital stock of

any class or of any rights, (D) the approval of any shareholders of the Company shall be required in connection with any reclassification

of Common Shares, any consolidation or merger to which the Company is a party, any sale or transfer of all or substantially all of the

assets of the Company, or any compulsory share exchange whereby the Common Shares are converted into other securities, cash or property,

or (E) the Company shall authorize the voluntary or involuntary dissolution, liquidation or winding up of the affairs of the Company,

then, in each case, the Company shall cause to be delivered by facsimile or email to the Holder at its last facsimile number or email

address as it shall appear upon the Warrant Register of the Company, at least 20 calendar days prior to the applicable record or effective

date hereinafter specified, a notice stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution,

redemption, rights or warrants, or if a record is not to be taken, the date as of which the holders of Common Shares of record to be entitled

to such dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on which such reclassification, consolidation,

merger, sale, transfer or share exchange is expected to become effective or close, and the date as of which it is expected that holders

of Common Shares of record shall be entitled to exchange their Common Shares for securities, cash or other property deliverable upon such

reclassification, consolidation, merger, sale, transfer or share exchange; provided that the failure to deliver such notice or any defect

therein or in the delivery thereof shall not affect the validity of the corporate action required to be specified in such notice. To the

extent that any notice provided in this Warrant constitutes, or contains, material, non-public information regarding the Company or any

of its subsidiaries, the Company shall simultaneously file such notice with the Commission pursuant to a Current Report on Form 8-K. The

Holder shall remain entitled to exercise this Warrant during the period commencing on the date of such notice to the effective date of

the event triggering such notice except as may otherwise be expressly set forth herein.

Section 4.

Transfer of Warrant.

a) Transferability.

The Holder of this Warrant agrees by his, her or its acceptance hereof, that such Holder will not sell, transfer, assign, pledge or hypothecate

this Warrant, in whole or in part, whether voluntarily, involuntarily, by operation of law or otherwise, without the prior written consent

of the Company (the “Written Consent”), which the Company may grant or withhold in its sole discretion. Any attempted transfer,

assigning, pledging or hypothecating in violation of this Section 4(a) shall be null and void ab initio and shall confer no rights on

any purported assignee. Upon the Company’s Written Consent, transfers to others, in whole or in part, may be made subject to compliance

with or exemptions from applicable securities laws. In order to make any permitted assignment, the Holder must deliver to the Company

the assignment form attached hereto duly executed and completed, together with the Purchase Warrant and payment of all transfer taxes,

if any, payable in connection therewith. The Company shall within ten (10) Business Days transfer this Warrant on the books of the Company

and shall execute and deliver a new Warrant or Warrants of like tenor to the appropriate assignee(s) expressly evidencing the right to

purchase the aggregate number of Shares purchasable hereunder or such portion of such number as shall be contemplated by any such assignment.

b) New Warrants.

This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of the Company, together

with a written notice specifying the names and denominations in which new Warrants are to be issued, signed by the Holder or its agent

or attorney. Subject to compliance with Section 4(a), as to any transfer which may be involved in such division or combination, the Company

shall execute and deliver a new Warrant or Warrants in exchange for the Warrant or Warrants to be divided or combined in accordance with

such notice. All Warrants issued on transfers or exchanges shall be dated the Issue Date of this Warrant and shall be identical with

this Warrant except as to the number of Warrant Shares issuable pursuant thereto.

c) Warrant

“Warrant Register”), in the name of the record Holder hereof from time to time. The Company may deem and treat

the registered Holder of this Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the

Holder, and for all other purposes, absent actual notice to the contrary.

d) Transfer

Restrictions. If, at the time of the surrender of this Warrant in connection with any transfer of this Warrant, this Warrant shall

not be either (i) registered pursuant to an effective registration statement under the Securities Act and under applicable state securities

or blue sky laws or (ii) eligible for resale without volume or manner-of-sale restrictions or current public information requirements

pursuant to Rule 144, the Company may require, as a condition of allowing such transfer, that (i) the Holder of this Warrant shall provide

to the Company an opinion of counsel selected by the Holder and reasonably acceptable to the Company, to the effect that such transfer

does not require registration of this Warrant under the Securities Act, and (ii) the transferee will agree to the imprinting of the legend

on this Warrant (in addition to any legend required by applicable state securities or “blue sky” laws.

e) Representation

by the Holder. The Holder, by the acceptance hereof, represents and warrants that it is acquiring this Warrant and, upon any exercise

hereof, will acquire the Warrant Shares issuable upon such exercise, for its own account and not with a view to or for distributing or

reselling such Warrant Shares or any part thereof in violation of the Securities Act or any applicable state securities law, except pursuant

to sales registered or exempted under the Securities Act.

Section 5.

Miscellaneous.

a) No Rights

as Shareholder Until Exercise. This Warrant does not entitle the Holder to any voting rights, dividends or other rights as a shareholder

of the Company prior to the exercise hereof as set forth in Section 2(d)(i), except as expressly set forth in Section 3.

b) Loss, Theft,

Destruction or Mutilation of Warrant. The Company covenants that upon receipt by the Company of evidence reasonably satisfactory

to it of the loss, theft, destruction or mutilation of this Warrant or any share certificate relating to the Warrant Shares, and in case

of loss, theft or destruction, of indemnity or security reasonably satisfactory to it (which, in the case of the Warrant, shall not include

the posting of any bond), and upon surrender and cancellation of such Warrant or share certificate, if mutilated, the Company will make

and deliver a new Warrant or share certificate of like tenor and dated as of such cancellation, in lieu of such Warrant or share certificate.

c) Fridays,

Saturdays, Sundays, Holidays, etc. If the last or appointed day for the taking of any action or the expiration of any right required

or granted herein shall not be a Business Day, then, such action may be taken or such right may be exercised on the next succeeding Business

Day.

d) Authorized

Shares.

The Company covenants that it has reserved

and will continue to reserve and keep available so long as this Warrant remains outstanding, free of preemptive rights, from its authorized

and unissued Common Shares a sufficient number of shares to provide for the issuance of the Warrant Shares upon the exercise of any purchase

rights under this Warrant. The Company further covenants that its issuance of this Warrant shall constitute full authority to its officers

who are charged with the duty of issuing the necessary Warrant Shares upon the exercise of the purchase rights under this Warrant. The

Company will take all such reasonable action as may be necessary to assure that such Warrant Shares may be issued as provided herein without

violation of any applicable law or regulation, or of any requirements of the Trading Market upon which the Common Shares may be listed

(including the Tel Aviv Stock Exchange). The Company covenants that all Warrant Shares which may be issued upon the exercise of the purchase

rights represented by this Warrant will, upon exercise of the purchase rights represented by this Warrant and payment for such Warrant

Shares in accordance herewith, be duly authorized, validly issued, fully paid and nonassessable and free from all taxes, liens and charges

created by the Company in respect of the issue thereof (other than taxes in respect of any transfer occurring contemporaneously with such

issue).

Except and to the

extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending its certificate

of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of securities or

any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will at all

times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate

to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the generality of the foregoing, the

Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor upon such exercise immediately prior

to such increase in par value, (ii) take all such action as may be necessary or appropriate in order that the Company may validly and

legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant and (iii) use commercially reasonable efforts

to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction thereof, as may be, necessary

to enable the Company to perform its obligations under this Warrant.

Before taking any

action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the Exercise Price,

the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from any public regulatory

body or bodies having jurisdiction thereof.

e) Governing

Law and Jurisdiction. All questions concerning the construction, validity, enforcement and interpretation of this Warrant will be

governed by and construed and enforced in accordance with the internal laws of the State of New York, without regard to the principle

of conflicts of law thereof. The Holder and the Company agree that all legal proceedings concerning the interpretations, enforcement

and defense of this Warrant (whether brought against the Company, the Holder or its respective affiliates, directors, officers, shareholders,

partners, members, employees or agents) shall be commenced exclusively in the state and federal courts sitting in the City of New York.

The Company and the Holder hereby irrevocably submits to the exclusive jurisdiction of the state and federal courts sitting in the City

of New York, Borough of Manhattan for the adjudication of any dispute hereunder or in connection herewith, and hereby irrevocably waives,

and agrees not to assert in any action or proceeding, any claim that it is not personally subject to the jurisdiction of any such court,

that such action or proceeding is improper or is an inconvenient venue for such proceeding. If any party shall commence an action or

proceeding to enforce any provisions of this Warrant, then the prevailing party in such action or proceeding shall be reimbursed by the

non-prevailing party for its reasonable attorneys’ fees and other costs and expenses incurred with the investigation, preparation

and prosecution of such action or proceeding.

f) Restrictions.

The Holder acknowledges that the Warrant Shares acquired upon the exercise of this Warrant, if not registered by the Company, will

have restrictions upon resale imposed by state and federal securities laws.

g) Nonwaiver

and Expenses. No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall operate as

a waiver of such right or otherwise prejudice the Holder’s rights, powers or remedies. Without limiting any other provision of this

Warrant, if the Company willfully and knowingly fails to comply with any provision of this Warrant, which results in any material damages

to the Holder, the Company shall pay to the Holder such amounts as shall be sufficient to cover any costs and expenses including, but

not limited to, reasonable attorneys’ fees, including those of appellate proceedings, incurred by the Holder in collecting any amounts

due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.

h) Notices.

All notices or other communications required or permitted to be given by the Company to the Holder or by the Holder to the Company shall

be delivered in writing in accordance with the notice details set forth below:

If to the Company:

Pluri Inc.

Matam Advanced Technology Park, Building

No. 5

Haifa, Israel 3508409

Attention: Liat Zalts, Chief Financial

Officer

E-mail: liat.zalts@Pluri-biotech.com.

If to the Holder:

Chutzpah Holdings LP

337 WINSTON ROAD OAKVILLE

Ontario (CA-ON), L6L

4W6 CANADA

Attention: Alejandro Weinstein

E-mail: alexandre@bechutzpah.ch

i) Limitation

of Liability. No provision hereof, in the absence of any affirmative action by the Holder to exercise this Warrant to purchase Warrant

Shares, and no enumeration herein of the rights or privileges of the Holder, shall give rise to any liability of the Holder for the purchase

price of Common Shares or as a shareholder of the Company, whether such liability is asserted by the Company or by creditors of the Company.

j) Remedies.

The Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will be entitled to specific

performance of its rights under this Warrant. The Company agrees that monetary damages would not be adequate compensation for any loss

incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive and not to assert the defense in any

action for specific performance that a remedy at law would be adequate.

k) Successors

and Assigns. Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall inure to

the benefit of and be binding upon the successors and permitted assigns (provided that a Written Consent was obtained in accordance

with Section 4(a)) of the Company and the Holder. The provisions of this Warrant are intended to be for the benefit of the Holder,

and in accordance with Section 4(a), for the benefit of any Holder from time to time of this Warrant and shall be enforceable by the

Holder or holder of Warrant Shares.

l) Amendment.

This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company and the Holder.

m) Severability.

Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid under applicable law,

but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall be ineffective to the

extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining provisions of this Warrant.

n) Headings.

The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed a part of this Warrant.

********************

(Signature Page Follows)

IN WITNESS WHEREOF, the Company

has caused this Warrant to be executed by its officer thereunto duly authorized as of the date first above indicated.

PLURI INC.

By:

Name:

Yaky Yanay

Title:

President & Chief Executive Officer

By:

Name:

Liat Zalts

Title:

Chief Financial Officer & Treasurer

EXHIBIT A

NOTICE OF EXERCISE

TO: pluri

inc.

(1) The

undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant (only if exercised

in full), and tenders herewith payment of the exercise price in full, together with all applicable transfer taxes, if any.

(2) Payment

shall take the form of (check applicable box):

☐ in

lawful money of the United States

(3) Please

issue said Warrant Shares in the name of the undersigned or in such other name as is specified below:

_______________________________

The Warrant Shares shall be delivered to the following

DWAC Account Number:

_______________________________

__________________________

[SIGNATURE

OF HOLDER]

Name of Investing Entity:

______________________________________________

Signature of Authorized Signatory of Investing

Entity:

_____________________________________

Name of Authorized Signatory:

_____________________________________

Title of Authorized Signatory:

Date: ________________________________

EXHIBIT B

ASSIGNMENT FORM

(To be completed only

in connection with a transfer approved by the Company in accordance with Section 4(a) of this Warrant. Do not use this form to purchase

shares.)

FOR VALUE RECEIVED, _________

does hereby sell, assign and transfer unto the right to purchase Common Shares of Pluri Inc. (the “Company”), a Nevada company,

evidenced by this Warrant and does hereby authorize the Company to transfer such right on the books of the Company.

Name of Assignee (must be identical to the transferee approved in writing by the Company):

(Please Print)

Address of Assignee:

Phone Number of Assignee:

Email Address of Assignee:

(Please Print)

______________________________________

Tax Identification No. or equivalent, if applicable

The undersigned acknowledges that this transfer

has been expressly approved by the Company pursuant to Section 4(a) of the Warrant, and that any transfer made without such prior written

consent is null and void.

Date: ________________________________

____________________________________

(Signature of Holder)

__________________________________

(Name of Holder - please print)

EX-10.1 — SECURITIES PURCHASE AGREEMENT

EX-10.1

Filename: ea028365301ex10-1.htm · Sequence: 3

Exhibit 10.1

SECURITIES

PURCHASE AGREEMENT

This

Securities Purchase Agreement (this “Agreement”) is dated as of March 24, 2026, between Pluri Inc.,

a Nevada corporation (the “Company”), and the purchaser identified on the signature pages hereto (including its successors

and assigns, the “Purchaser”).

WHEREAS,

subject to the terms and conditions set forth in this Agreement and pursuant to Section 4(a)(2) of the Securities Act of 1933, as amended

(the “Securities Act”) and Rule 506(b) of Regulation D and Rule 903 of Regulation S promulgated thereunder, the Company

desires to issue and sell to the Purchaser, and the Purchaser desires to purchase from the Company, (i) Common Shares, and (ii) Common

Warrants to purchase Common Shares equal to 100% of the sum of the Common Shares purchased by the Purchaser hereunder, as each such term

is defined below and more fully described in this Agreement;

NOW,

THEREFORE, IN CONSIDERATION of the mutual covenants contained in this Agreement, and for other good and valuable consideration the receipt

and adequacy of which are hereby acknowledged, the Company and the Purchaser agree as follows:

ARTICLE

DEFINITIONS

1.1

Definitions. In addition to the terms defined elsewhere in this Agreement, for all purposes of this Agreement, the following terms

have the meanings set forth in this Section 1.1:

“Affiliate”

means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control

with a Person as such terms are used in and construed under Rule 405 under the Securities Act.

“Business

Day” means any day except any Friday, Saturday Sunday, any day which is a federal legal holiday in the United States, a legal

holiday in the State of Israel, or any day on which banking institutions in the State of New York or the State of Israel are authorized

or required by law or other governmental action to close.

“Closing”

means the closing of the purchase and sale of the Shares pursuant to Section 2.1.

“Closing

Date” means the Trading Day on which all of the Transaction Documents have been executed and delivered by the applicable parties

thereto, and all conditions precedent to (i) the Purchaser’s obligations to pay the Subscription Amount and (ii) the Company’s

obligations to deliver the Shares, in each case, have been satisfied or waived.

“Commission”

means the United States Securities and Exchange Commission.

“Common

Shares” means the common shares of the Company, par value $0.00001 per share, and any other class of securities into which

such securities may hereafter be reclassified or changed.

“Common

Warrant” means the Common Shares purchase warrant delivered to the Purchaser at the Closing in accordance with Section 2.2(a)

hereof, in substantially the form of Exhibit A attached hereto.

“Disclosure

Time” means, (i) if this Agreement is signed on a day that is not a Trading Day or after 9:00 a.m. (New York City time) and

before midnight (New York City time) on any Trading Day, 9:01 a.m. (New York City time) on the Trading Day immediately following the

date hereof, and (ii) if this Agreement is signed between midnight (New York City time) and 9:00 a.m. (New York City time) on any Trading

Day, no later than 9:01 a.m. (New York City time) on the date hereof.

“Exchange

Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder.

“Holder”

shall have the meaning ascribed to such term in Section 4.8(a).

“Liens”

means a lien, charge, pledge, security interest, encumbrance, right of first refusal, preemptive right or other restriction.

“Material

Adverse Effect” means (i) a material adverse effect on the legality, validity or enforceability of any Transaction Document,

(ii) a material adverse effect on the results of operations, assets, business, prospects or condition (financial or otherwise) of the

Company and its subsidiaries, taken as a whole, or (iii) a material adverse effect on the Company’s ability to perform in any material

respect on a timely basis its obligations under any Transaction Document.

“Per

Share Purchase Price” means $4.00, subject to adjustment for reverse and forward stock splits, stock dividends,

stock combinations and other similar transactions of shares of Common Stock that occur between the date hereof and the Closing Date.

“Person”

means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability

company, joint stock company, government (or an agency or subdivision thereof) or other entity of any kind.

“Proceeding”

means an action, claim, suit, investigation or proceeding (including, without limitation, an informal investigation or partial proceeding,

such as a deposition) pending or, to the Company’s knowledge, threatened in writing against or affecting the Company, any Subsidiary

or any of their respective properties before or by any court, arbitrator, governmental or administrative agency or regulatory authority

(federal, state, county, local or foreign).

“SEC

Reports” shall have the meaning ascribed to such term in Section 3.1(e). “Securities” means the Shares,

the Warrants and the Warrant Shares.

“Securities

Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.

“Shares”

means the Common Shares issued or issuable to the Purchaser pursuant to this Agreement.

“Short

Sales” means all “short sales” as defined in Rule 200 of Regulation SHO under the Exchange Act (but shall not be

deemed to include locating and/or borrowing Common Shares).

“Subscription

Amount” means, the aggregate amount of $2.5 million to be paid by the Purchaser for Shares and Warrants purchased

hereunder as specified below such Purchaser’s name on the signature page of this Agreement and next to the heading “Subscription

Amount,” in United States dollars and in immediately available funds.

“Trading

Day” means a day on which the principal Trading Market is open for trading.

“Trading

Market” means any of the following markets or exchanges on which the Common Shares are listed or quoted for trading on the

date in question: the Nasdaq Capital Market and the Tel Aviv Stock Exchange (or any successors to any of the foregoing).

“Transaction

Documents” means this Agreement, the Warrants and all exhibits and schedules thereto and hereto and any other documents or

agreements executed in connection with the transactions contemplated hereunder.

“Transfer

Agent” means Equiniti Trust Company, LLC, the current transfer agent of the Company, with a mailing address of 55 Challenger

Road, Floor 2, Ridgefield Park, NJ 07660, and any successor transfer agent of the Company.

“Warrants”

means the Common Warrant.

“Warrant

Shares” means the shares of Common Shares issuable upon exercise of the Warrants.

ARTICLE

II.

PURCHASE

AND SALE

2.1

Closing. On the Closing Date, upon the terms and subject to the

conditions set forth herein, substantially concurrent with the execution and delivery of this Agreement by the parties hereto, the Company

agrees to sell, and the Purchaser agrees to purchase (i) the number of Common Shares set forth under the heading “Number of Shares”

on the Purchaser’s signature page hereto, at the Per Share Purchase Price, and (ii) Common Warrants to purchase up to the amount

of Common Shares set forth under the heading “Common Warrants” on the Purchaser’s signature page hereto, exercisable

for Common Shares as calculated pursuant to Section 2.2(a). Prior to Closing, the Purchaser shall deliver to the Company, via wire transfer

of immediately available funds in cash equal to its Subscription Amount, and as of the Closing (i) the Company shall deliver to the Purchaser

the Shares and the Warrants, and (ii) the Company and the Purchaser shall deliver the other items set forth in Section 2.2 deliverable

at the Closing. Upon satisfaction of the covenants and conditions set forth in Sections 2.2 and 2.3, the Closing shall occur at the offices

of legal counsel to the Company or such other location as the parties shall mutually agree (and such Closing may be undertaken remotely

by electronic exchange of documentation).

2.2

Deliveries.

(a)

On or prior to the Closing Date, the Company shall deliver or cause to

be delivered to the Purchaser the following:

(i)

this Agreement duly executed by the Company;

(ii)

on the Closing Date, the Company shall cause the Transfer Agent to issue

to the Purchaser in global form through a book-entry account maintained by the Transfer Agent, the number of Common Shares set forth

on such Purchaser’s signature page hereto, registered in the name of such Purchaser;

(iii)

on the Closing Date, an originally singed Common Warrant registered in

the name of the Purchaser to purchase up to the number of Common Shares equal to 100% of Shares, with an exercise price equal to $4.25

per share, subject to adjustment therein;

(iv)

on the Closing Date, the Purchaser shall have received a certificate

signed by each of the Chief Executive Officer and Chief Financial Officer of the Company certifying to the fulfillment of the conditions

set forth in Section 2.3(b); and

(v)

on the Closing Date, the Purchaser shall have received an opinion of

Sullivan & Worcester LLP, counsel for the Company, dated as of the Closing Date in a form reasonably acceptable to the Purchaser.

(b)

On or prior to the Closing Date, the Purchaser shall deliver or cause

to be delivered to the Company the following:

(i)

this Agreement duly executed by the Purchaser;

(ii)

if the Purchaser is an Accredited Investor (as defined herein), an executed

copy of the Accredited Investor Questionnaire set forth on Exhibit B-1;

(iii)

if the Purchaser is a Non-U.S. Person (as defined herein), an executed

copy of the Regulation S Questionnaire set forth on Exhibit B-2; and

(iv)

the Purchaser’s Subscription Amount, which shall be made available

for “Delivery Versus Payment” settlement with the Company or its designees.

2.3

Closing Conditions.

(a)

The obligations of the Company hereunder in connection with the Closing

are subject to the following conditions being met:

(i)

the accuracy in all material respects (or, to the extent representations

or warranties are qualified by materiality or Material Adverse Effect, in all respects) when made and on the Closing Date of the representations

and warranties of the Purchaser contained herein (unless as of a specific date therein in which case they shall be accurate as of such

date);

(ii)

all obligations, covenants and agreements of the Purchaser required to

be performed at or prior to the Closing Date shall have been performed; and

(iii)

the delivery by the Purchaser of the items set forth in Section 2.2(b)

of this Agreement.

(b)

The respective obligations of the Purchaser hereunder in connection with

the Closing are subject to the following conditions being met:

(i)

the accuracy in all material respects (or, to the extent representations

or warranties are qualified by materiality or Material Adverse Effect, in all respects) when made and on the Closing Date of the representations

and warranties of the Company contained herein (unless as of a specific date therein in which case they shall be accurate as of such

date);

(ii)

all obligations, covenants and agreements of the Company required to

be performed at or prior to the Closing Date shall have been performed;

(iii)

the delivery by the Company of the items set forth in Section 2.2(a)

of this Agreement;

(iv)

there shall have been no Material Adverse Effect with respect to the

Company since the date hereof;

(v)

the Company shall have filed additional listing applications and/or notices

of each of the Nasdaq Capital Market and the Tel Aviv Stock Exchange (the “TASE”) for the listing of the Common Shares

and the Warrant Shares issued and issuable to the Purchaser pursuant to the Transaction Documents; and

(vi)

the Company shall have obtained any and all consents, permits, approvals,

registrations and waivers necessary for the consummation of the purchase and sale of the Securities and the consummation of the other

transactions contemplated by this Agreement, including the waiver of any applicable registration rights that could affect the rights

of the Purchaser hereunder, all of which shall be in full force and effect.

ARTICLE

III.

REPRESENTATIONS

AND WARRANTIES

3.1

Representations and Warranties of the Company. The Company hereby

makes the following representations and warranties to the Purchaser:

(a)

Organization and Standing. Each of the Company and each of its

subsidiaries has been (i) duly organized and is validly existing and in good standing (where such concept exists) under the laws of its

jurisdiction of organization, with power and authority (corporate and other) to own its properties and conduct its business as currently

conducted, and (ii) duly qualified as a foreign corporation for the transaction of business and is in good standing (where such concept

exists) under the laws of each other jurisdiction in which it owns or leases properties or conducts any business so as to require such

qualification, except where the failure to be so qualified or in good standing would not, individually or in the aggregate, have a Material

Adverse Effect. The certificate of incorporation, articles of association and by-laws (and other applicable organizational documents)

of the Company and each of its subsidiaries comply with the requirements of applicable law in its jurisdiction of incorporation and are

in full force and effect and except as set forth in the SEC Reports, the Company owns, directly or through subsidiaries, all of the issued

outstanding equity securities of each of its subsidiaries.

(b)

Corporate Power; Authorization. This Agreement and each of the

other Transaction Documents has been duly authorized, executed and delivered by the Company; the Company has all requisite corporate

power and authority to execute, deliver and perform its obligations under this Agreement and each of the other Transaction Documents.

This Agreement and each of the other Transaction Documents is the valid and binding obligation of the Company enforceable against the

Company in accordance with its terms, except (i) as limited by general equitable principles and applicable bankruptcy, insolvency, reorganization,

moratorium and other laws of general application affecting enforcement of creditors’ rights generally, (ii) as limited by laws

relating to the availability of specific performance, injunctive relief or other equitable remedies and (iii) insofar as indemnification

and contribution provisions may be limited by applicable law.

(c)

Issuance and Delivery of the Securities. The Shares have been

duly authorized and, when issued and paid for in compliance with the provisions of this Agreement, will be validly issued, fully paid

and non-assessable, and issued in compliance with all applicable law. The Warrants have been duly authorized by the Company and when

executed and delivered by the Company will be valid and binding agreements of the Company, enforceable against the Company in accordance

with their terms. The issuance and delivery of the Shares or Warrants is not subject to preemptive, co-sale, right of first refusal or

any other similar rights of the shareholders of the Company or any other Person or any liens or encumbrances. The Warrant Shares have

been duly authorized and reserved for issuance and, when issued and delivered upon valid exercise of the Warrants in accordance therewith,

will be validly issued, fully paid and nonassessable and issued in compliance with all applicable law, and not subject to preemptive,

co-sale, right of first refusal or any other similar rights of the shareholders of the Company or any other Person or any liens or encumbrances.

(d)

Registration Exemption. The offer and issuance by the Company

of the Securities is exempt from registration under the Securities Act.

(e)

SEC Reports. The Company is subject to the reporting requirements

of the Exchange Act, and has filed or will file in a timely manner all reports, schedules, forms, statements and other documents that

the Company was or is required to file with the Commission under either the Securities Act or the Exchange Act, since becoming subject

to the requirements of the Exchange Act (the foregoing documents (together with any documents filed by the Company under the Securities

Act or Exchange Act, whether or not required), and in each case including all exhibits and schedules thereto and documents incorporated

by reference therein and including all registration statements and prospectuses filed with the Commission, but excluding any information

for which the Company has received confidential treatment from the Commission, being collectively referred to herein as the “SEC

Reports”), all of which are available on the Commission’s EDGAR system. As of their respective filing or furnishing dates

(or, if amended prior to the date of this Agreement, when amended), all SEC Reports (including any audited or unaudited financial statements

and any notes thereto or schedules included therein) complied in all material respects with the requirements of the Securities Act or

the Exchange Act, as the case may be, and the rules and regulations of the Commission promulgated thereunder. None of the SEC Reports

as of their respective filing or furnishing dates contained any untrue statement of material fact or omitted to state a material fact

required to be stated therein or necessary to make the statements made therein, in light of the circumstances under which they were made,

not misleading. There are no material outstanding or unresolved comments in comment letters from the staff of the Division of Corporation

Finance of the Commission with respect to any SEC Reports.

(f)

Tel Aviv Stock Exchange Reporting. All statements, reports, schedules,

forms and other documents (and all exhibits, supplements and amendments) required to have been published and/or filed by the Company

pursuant to applicable law with the Israel Securities Authority and the TASE have been so published and/or filed and/or furnished, as

applicable, on a timely basis (the “TASE Reporting Document”). As of the time it was published and/or filed and/or

furnished, as applicable, other than as corrected in a subsequent TASE Reporting Document: (i) each of the TASE Reporting Documents complied

in all material respects with applicable laws as in effect on the date such TASE Reporting Document was filed; and (ii) none of the TASE

Reporting Documents contained any untrue statement of a material fact or omitted to state a material fact required to be stated therein

or necessary in order to make the statements therein, in the light of the circumstances under which they were made, not misleading.

(g)

No General Solicitation. Neither the Company, nor any of its Affiliates,

nor any Person acting on its or their behalf, has engaged in any form of general solicitation or general advertising (within the meaning

of Regulation D promulgated under the Securities Act) in connection with the offer or sale of the Securities.

(h)

No “Bad Actor” Disqualification. No “bad actor”

disqualifying event described in Rule 506(d)(1)(i)-(viii) of the Securities Act (a “Disqualification Event”) is applicable

to the Company or, to the Company’s knowledge, any Company Covered Person (as defined below), except for a Disqualification Event

to which Rule 506(d)(2)(ii-iv) or (d)(3) is applicable. “Company Covered Person” means, with respect to the Company

as an “issuer” for purposes of Rule 506 promulgated under the Securities Act, any person listed in the first paragraph of

Rule 506(d)(1).

(i)

No Material Adverse Effect. Except as otherwise disclosed in the

SEC Reports, subsequent to the respective dates as of which information is given in the SEC Reports: (i) there has been no change which

has had or would reasonably be expected to result in a Material Adverse Effect; (ii) the Company and its subsidiaries, considered as

one entity, have not incurred any material liability or obligation, indirect, direct or contingent, not in the ordinary course of business

nor entered into any material transaction or agreement not in the ordinary course of business; (iii) there has been no dividend or distribution

of any kind declared, paid or made by the Company; (iv) no executive officer or director of the Company has resigned from any position

with the Company; and (v) there has not been any Material Adverse Effect in the Company’s long-term or short-term debt.

(j)

Independent Accountants. To the knowledge of the Company, Kesselman

& Kesselman, whose report is filed with the Commission and included or incorporated by reference in the SEC Reports, is an independent

registered public accounting firm as required by the Securities Act and the Public Company Accounting Oversight Board and a member firm

of PricewaterhouseCoopers International Limited. Kesselman & Kesselman has not, during the periods covered by the financial statements

included or incorporated by reference in the SEC Reports, provided to the Company any non-audit services, as such term is used in Section

10A(g) of the Exchange Act.

(k)

Financial Statements. The financial statements filed with the

Commission and included in the SEC Reports, together with the related notes and schedules, present fairly, in all material respects,

the consolidated financial position of the Company and its subsidiaries as of and at the dates indicated and the results of their operations

and cash flows for the periods therein specified. Such financial statements and supporting schedules have been prepared in conformity

with U.S. generally accepted accounting principles (“GAAP”) applied on a consistent basis throughout the periods involved,

except as may be expressly stated in the related notes thereto, provided, that, unaudited interim financial statements are subject to

year-end audit adjustments that are not expected to be material in the aggregate and do not contain all footnotes required by GAAP. No

other financial statements or supporting schedules are required to be included in or incorporated by reference in the SEC Reports.

(l)

[Reserved].

(m)

Statistical and Marketing-Related Data. The statistical and market-related

data included or incorporated by reference in SEC Reports are based on or derived from sources that the Company reasonably and in good

faith believes are reliable and accurate or represent the Company’s good faith estimates that are made on the basis of data derived

from such sources.

(n)

XBRL. The interactive data in eXtensible Business Reporting Language

included or incorporated by reference in the SEC Reports fairly presents the information called for in all material respects and has

been prepared in accordance with the Commission’s rules and guidelines applicable thereto.

(o)

Capitalization. The authorized share capital of the Company is

as set forth on Schedule 3.1(o). As set forth in the SEC Reports as of the date set forth therein, all of the issued and outstanding

Common Shares of the Company have been duly and validly authorized and issued and are fully paid and non-assessable, have been issued

in compliance with all applicable law, and conform to the description of the Common Shares contained in the SEC Reports; and all of the

issued shares of each subsidiary of the Company have been duly and validly authorized and issued, are fully paid and non-assessable are

owned directly or indirectly by the Company, free and clear of all liens, encumbrances, equities or claims, except for such liens or

encumbrances described in the SEC Reports, there are no options, warrants, agreements, contracts or other rights in existence to purchase

or acquire from the Company any shares of the share capital of the Company; the Common Shares to be issued and sold by the Company to

the Purchaser hereunder have been duly and validly authorized and, when issued and delivered against payment therefor as provided herein,

will be duly and validly issued and fully paid and non-assessable and will conform to the description of the ordinary shares contained

in the SEC Reports; the issuance of the Shares is not subject to any preemptive or similar rights; the description of the Company’s

share option, RSUs, share bonus and other share plans or arrangements (the “Company Share Plans”), and the options

and other equity incentive awards or other rights granted thereunder (collectively, the “Options”), set forth in the

SEC Reports accurately and fairly presents the information required to be shown with respect to such plans, arrangements, options and

rights; each grant of an Option (A) was duly authorized no later than the date on which the grant of such Option was by its terms to

be effective by all necessary corporate action, including, as applicable, approval by the board of directors of the Company (or a duly

constituted and authorized committee thereof) and any required shareholder approval by the necessary number of votes or written consents,

and the award agreement governing such grant (if any) was duly executed and delivered by each party thereto, (B) that was intended to

qualify for either the “capital gains track” or the “employment income track” of Section 102 of the Israeli Income

Tax Ordinance (New Version), 5721-1961, and the rules and regulations promulgated thereunder, so qualifies as was indicated with respect

to each such Option at the date that such Option was granted, and (C) was made in accordance with the terms of the applicable Company

Share Plan and applicable laws and regulatory rules or requirements, including all applicable federal and Israeli securities laws.

(p)

Non-Contravention of Existing Instruments; No Further Authorizations

or Approvals Required. The Company’s execution, delivery and performance of this Agreement and consummation of the transactions

contemplated hereby or by the Transaction Documents (including the issuance and sale of the Securities and the use of the proceeds from

the sale of the Securities will not (A) result in a material breach or violation of any of the terms and provisions of, or constitute

a default under, any law, order, rule or regulation to which the Company or any subsidiary is subject (including, without limitation,

those promulgated by the Food and Drug Administration of the U.S. Department of Health and Human Services (the “FDA”)

or by any foreign, federal, state or local regulatory authority performing functions similar to those performed by the FDA), or by which

any property or asset of the Company or any subsidiary is bound or affected, (B) conflict with, result in any violation or breach of,

or constitute a default (or an event that with notice or lapse of time or both would become a default) under, or give to others any right

of termination, amendment, acceleration or cancellation (with or without notice, lapse of time or both) (a “Default Acceleration

Event”) of, any agreement, lease, credit facility, debt, note, bond, mortgage, indenture or other instrument (“Contract”)

or obligation or other understanding to which the Company or any subsidiary is a party or by which any property or asset of the Company

or any subsidiary is bound or affected or any instrument of approval granted to it by the Israel Innovation Authority of the Israeli

Ministry of Economy and Industry or any instrument of approval granted to any of them by the Authority for Investment and Development

of Industry and the Economy of the Israeli Ministry of Economy and Industry, except to the extent that such conflict, default, or Default

Acceleration Event is not reasonably likely to result in a Material Adverse Effect, or (C) result in a breach or violation of any of

the terms and provisions of, or constitute a default under, the Company’s articles of incorporation (as the same may be amended

or restated from time to time) or bylaws (as the same may be amended or restated from time to time). Except as set forth in the SEC Reports,

neither the Company nor any of its subsidiaries is in violation, breach or default under its articles of incorporation (as the same may

be amended or restated from time to time), bylaws (as the same may be amended or restated from time to time) or other equivalent organizational

or governing documents. The Company nor, to its knowledge, any other party is in violation, breach or default of any Contract that has

resulted in or could reasonably be expected to result in a Material Adverse Effect. Each approval, consent, order, authorization, designation,

declaration or filing by or with any regulatory, administrative or other governmental body necessary in connection with the execution

and delivery by the Company of this Agreement and the performance of the Company of the transactions herein contemplated has been obtained

or made and is in full force and effect.

(q)

No Material Actions or Proceedings. There is no action, suit,

proceeding, inquiry, arbitration, investigation, litigation or governmental proceeding pending or, to the Company’s knowledge,

threatened against, or involving the Company or, to the Company’s knowledge, any executive officer or director of the Company including

any proceeding before the FDA or comparable federal, state, local or foreign governmental bodies (it being understood that the interaction

between the Company and the FDA and such comparable governmental bodies relating to the clinical development and product approval process

shall not be deemed proceedings for purposes of this representation), which is required to be disclosed and has not been disclosed in

the SEC Reports, except as would not, individually or in the aggregate, reasonably be expected to have a Material Adverse Effect.

(r)

Labor Disputes. Except as set forth in the SEC Reports, there

is not pending or, to the knowledge of the Company, threatened, any action, suit or proceeding to which the Company or any of its subsidiaries

is a party or of which any property or assets of the Company or any of its subsidiaries is the subject before or by any court or governmental

agency, authority or body, or any arbitrator or mediator, except as would not, individually or in the aggregate, reasonably be expected

to have a Material Adverse Effect.

(s)

Compliance with Certain Applicable Laws. The Company: (A) is and

at all times has been in compliance with all statutes, rules, or regulations applicable to the ownership, testing, development, manufacture,

packaging, processing, use, distribution, marketing, labeling, promotion, sale, offer for sale, storage, import, export or disposal of

any product manufactured or distributed by the Company (“Applicable Laws”), except as could not, individually or in

the aggregate, reasonably be expected to have a Material Adverse Effect; (B) has not received any warning letter, untitled letter or

other correspondence or notice from any governmental authority alleging or asserting noncompliance with any Applicable Laws or any licenses,

certificates, approvals, clearances, authorizations, permits and supplements or amendments thereto required by any such Applicable Laws

(“Authorizations”) the receipt of which could, individually or in the aggregate, reasonably be expected to have a

Material Adverse Effect; (C) possesses all material Authorizations and such Authorizations are valid and in full force and effect and

are not in material violation of any term of any such Authorizations; (D) has not received notice of any claim, action, suit, proceeding,

hearing, enforcement, investigation, arbitration or other action from any governmental authority or third party alleging that any product

operation or activity is in violation of any Applicable Laws or Authorizations and has no knowledge that any such governmental authority

or third party is considering any such claim, litigation, arbitration, action, suit, investigation or proceeding, the receipt of which

could, individually or in the aggregate, reasonably be expected to have a Material Adverse Effect; (E) has not received notice that any

governmental authority has taken, is taking or intends to take action to limit, suspend, modify or revoke any Authorizations and has

no knowledge that any such governmental authority is considering such action; and (F) has filed, obtained, maintained or submitted all

material reports, documents, forms, notices, applications, records, claims, submissions and supplements or amendments as required by

any Applicable Laws or Authorizations and that all such reports, documents, forms, notices, applications, records, claims, submissions

and supplements or amendments were complete and correct on the date filed (or were corrected or supplemented by a subsequent submission).

(t)

Tax Law Compliance. Other than as disclosed in the SEC Reports,

except for matters that would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect

each of the Company and its subsidiaries has (a) filed all material foreign, federal, state and local tax returns (as hereinafter defined)

required to be filed with taxing authorities prior to the date hereof or has duly obtained extensions of time for the filing thereof

and (b) paid all taxes (as hereinafter defined) shown as due and payable on such returns that were filed and has paid all taxes imposed

on or assessed against the Company or such respective subsidiary. The provisions for taxes payable, if any, shown on the financial statements

included or incorporated by reference in the SEC Reports are sufficient for all accrued and unpaid taxes, whether or not disputed, and

for all periods to and including the dates of such consolidated financial statements. Other than as disclosed in the SEC Reports, no

material issues have been raised (and are currently pending) by any taxing authority in connection with any of the returns or taxes asserted

as due from the Company or its subsidiaries, and no waivers of statutes of limitation with respect to the returns or collection of taxes

have been given by or requested from the Company or its subsidiaries. There are no tax liens against the assets, properties or business

of the Company or any of its subsidiaries. The term “taxes” mean all federal, state, local, foreign, and other net income,

gross income, gross receipts, sales, use, ad valorem, transfer, franchise, profits, license, lease, service, service use, withholding,

payroll, employment, excise, severance, stamp, occupation, premium, property, windfall profits, customs, duties or other taxes, fees,

assessments, or charges of any kind whatever, together with any interest and any penalties, additions to tax, or additional amounts with

respect thereto. The term “returns” means all returns, declarations, reports, statements, and other documents required to

be filed in respect to taxes.

(u)

Company Not an “Investment Company”. The Company is

not, and will not be, either after receipt of payment for the Securities or after the application of the proceeds therefrom to register

as an “investment company” under the Investment Company Act of 1940, as amended (the “Investment Company Act”).

(v)

Insurance. The Company and each of its subsidiaries carries, or

is entitled to the benefits of insurance in such amounts and covering such risks, which the Company believes are adequate for the conduct

of its business and the value of its properties and as is customary for companies engaged in similar businesses in similar industries,

and all such insurance is in full force and effect. Neither the Company nor any of its subsidiaries has reason to believe that it will

not be able (i) to renew its existing insurance coverage as and when such policies expire or (ii) to obtain comparable coverage from

similar institutions as may be necessary or appropriate to conduct its business as now conducted and at a cost that would not result

in a Material Adverse Effect.

(w)

No Price Stabilization or Manipulation. The Company has not taken,

directly or indirectly, any action designed to or that might cause or result in stabilization or manipulation of the price of the Common

Shares or of any “reference security” (as defined in Rule 100 of Regulation M under the Exchange Act (“Regulation M”))

with respect to the Common Shares, whether to facilitate the sale or resale of the Securities or otherwise, and has taken no action which

would directly or indirectly violate Regulation M.

(x)

Related Party Transactions. There are no business relationships

or related party transactions involving the Company or any other person required to be described in the SEC Reports that have not been

described as required pursuant to the Securities Act.

(y)

Compliance with Environmental Laws. The Company and its subsidiaries

are in compliance with all foreign, federal, state and local rules, laws and regulations relating to the use, treatment, storage and

disposal of hazardous or toxic substances or waste and protection of health and safety or the environment which are applicable to their

businesses (“Environmental Laws”), except where the failure to comply has not had and would not reasonably be expected

to result in, singularly or in the aggregate, a Material Adverse Effect. There has been no storage, generation, transportation, handling,

treatment, disposal, discharge, emission, or other release of any kind of toxic or other wastes or other hazardous substances by, due

to, or caused by the Company or any of its subsidiaries (or, to the Company’s knowledge, any other entity for whose acts or omissions

the Company or any of its subsidiaries is or may otherwise be liable) upon any of the property now or previously owned or leased by the

Company or any of its subsidiaries, or upon any other property, in violation of any law, statute, ordinance, rule, regulation, order,

judgment, decree or permit or which would, under any law, statute, ordinance, rule (including rule of common law), regulation, order,

judgment, decree or permit, give rise to any liability, except for any violation or liability which has not had and would not reasonably

be expected to have, singularly or in the aggregate with all such violations and liabilities, a Material Adverse Effect; and there has

been no disposal, discharge, emission or other release of any kind onto such property or into the environment surrounding such property

of any toxic or other wastes or other hazardous substances with respect to which the Company or any of its subsidiaries has knowledge,

except for any such disposal, discharge, emission, or other release of any kind which would not have, singularly or in the aggregate

with all such discharges and other releases, a Material Adverse Effect.

(z)

Intellectual Property. The Company and each of its subsidiaries

own or possess or have valid rights to use all patents, patent applications, trademarks, service marks, trade names, trademark registrations,

service mark registrations, copyrights, licenses, inventions, trade secrets and similar rights (“Intellectual Property Rights”)

necessary for the conduct of the business of the Company and its subsidiaries as currently carried on and as described in the SEC Reports,

except as would not be reasonably likely to result in a Material Adverse Effect. To the knowledge of the Company, no action or use by

the Company or any of its subsidiaries necessary for the conduct of their business as currently carried on and as described in the SEC

Reports will involve or give rise to any infringement of, or license or similar fees for, any Intellectual Property Rights of others,

except where such action, use, license or fee is not reasonably likely to result in a Material Adverse Effect. Neither the Company nor

any of its subsidiaries have received any notice alleging any such infringement, fee or conflict with asserted Intellectual Property

Rights of others. Except as would not reasonably be expected to result, individually or in the aggregate, in a Material Adverse Effect

(A) to the knowledge of the Company, there is no infringement, misappropriation or violation by third parties of any of the Intellectual

Property Rights owned by the Company or any of its subsidiaries; (B) there is no pending or, to the knowledge of the Company, threatened

action, suit, proceeding or claim by others challenging the rights of the Company or any of its subsidiaries in or to any such Intellectual

Property Rights, and the Company is unaware of any facts which would form a reasonable basis for any such claim, that would, individually

or in the aggregate, together with any other claims in this Section 3.1(t), reasonably be expected to result in a Material Adverse Effect;

(C) the Intellectual Property Rights owned by the Company or any of its subsidiaries and, to the knowledge of the Company, the Intellectual

Property Rights licensed to the Company have not been adjudged by a court of competent jurisdiction invalid or unenforceable, in whole

or in part, and there is no pending or, to the Company’s knowledge, threatened action, suit, proceeding or claim by others challenging

the validity or scope of any such Intellectual Property Rights, and the Company is unaware of any facts which would form a reasonable

basis for any such claim that would, individually or in the aggregate, together with any other claims in this Section 3.1(t), reasonably

be expected to result in a Material Adverse Effect; (D) there is no pending or, to the Company’s knowledge, threatened action,

suit, proceeding or claim by others that the Company or any of its subsidiaries infringes, misappropriates or otherwise violates any

Intellectual Property Rights or other proprietary rights of others, neither the Company nor any of its subsidiaries has received any

written notice of such claim and the Company is unaware of any other facts which would form a reasonable basis for any such claim that

would, individually or in the aggregate, together with any other claims in this Section 3.1(t), reasonably be expected to result in a

Material Adverse Effect; and (E) except as disclosed in the SEC Reports, to the Company’s knowledge, no employee of the Company

or any of its subsidiaries is in or has ever been in violation in any material respect of any term of any employment contract, patent

disclosure agreement, invention assignment agreement, non-competition agreement, non-solicitation agreement, nondisclosure agreement

or any restrictive covenant to or with a former employer where the basis of such violation relates to such employee’s employment

with the Company or any of its subsidiaries, or actions undertaken by the employee while employed with the Company or any of its subsidiaries

and could reasonably be expected to result, individually or in the aggregate, in a Material Adverse Effect. To the Company’s knowledge,

all material technical information developed by and belonging to the Company or any of its subsidiaries which has not been patented has

been kept confidential. Neither the Company nor any of its subsidiaries is a party to or bound by any options, licenses or agreements

with respect to the Intellectual Property Rights of any other person or entity that are required to be set forth in the SEC Reports and

are not described therein. The SEC Reports contain in all material respects the same description of the matters set forth in the preceding

sentence. None of the technology employed by the Company or its subsidiaries has been obtained or is being used by the Company or any

of its subsidiaries in violation of any contractual obligation binding on the Company or any such subsidiary or, to the Company’s

knowledge, any of its or its subsidiaries’ officers, directors or employees, or otherwise in violation of the rights of any persons,

except for violations that would not result in a Material Adverse Effect.

(aa)

Brokers. Neither the Company nor any of its subsidiaries is a party to any contract, agreement or understanding with any person

(other than as contemplated by this Agreement) that would give rise to a valid claim against the Company or any of its subsidiaries or

the Purchaser for a brokerage commission, finder’s fee or like payment in connection with the offering and sale of the Securities

under this Agreement.

(bb)

No Outstanding Loans or Other Indebtedness. There are no outstanding loans, advances (except normal advances for business expenses

in the ordinary course of business) or guarantees or indebtedness by the Company or any of its subsidiaries to or for the benefit of

any of the officers or directors of the Company or executive officers of any of its subsidiaries to the extent such executive officers

may be deemed executive officers of the Company, or any of their respective family members, except as disclosed in the SEC Reports. The

Company has not directly or indirectly extended or maintained credit, arranged for the extension of credit, or renewed an extension of

credit, in the form of a personal loan to or for any director or executive officer of the Company.

(cc)

Broker-Dealer Status. Neither the Company nor any of its related entities (i) is required to register as a “broker”

or “dealer” in accordance with the provisions of the Exchange Act or (ii) directly or indirectly through one or more intermediaries,

controls or is a “person associated with a member” or “associated person of a member” (within the meaning of

Article I of the NASD Manual administered by FINRA). To the Company’s knowledge, there are no affiliations or associations between

any member of FINRA and any of the Company’s officers, directors or 5% or greater security holders, except as set forth in the

SEC Reports.

(dd)

Form S-3 Eligibility. The Company meets the applicable requirements for use of Form S-3 under the Securities Act, including compliance

with General Instruction I.B.1 or General Instruction I.B.6 of Form S-3, if and for so long as applicable. The Company is not a shell

company (as defined in Rule 405 under the Securities Act) and has not been a shell company for at least 12 calendar months previously

and if it has been a shell company at any time previously, has filed current Form 10 information (as defined in General Instruction I.B.6

of Form S-3) with the Commission at least 12 calendar months previously reflecting its status as an entity that is not a shell company.

(ee)

Compliance with Orders. Neither the Company nor any of its subsidiaries is in violation of any material judgment, decree, or order

of any court, arbitrator or other governmental authority.

(ff)

Sarbanes-Oxley Act. There is and has been no failure on the part of the Company or any of the Company’s directors or officers,

in their capacities as such, to comply in all material respects with any applicable provision of the Sarbanes-Oxley Act of 2002 and the

rules and regulations promulgated in connection therewith (the “Sarbanes-Oxley Act”), including Section 402 related

to loans and Sections 302 and 906 related to certifications.

(gg)

Disclosure Controls and Procedures. Except as set forth in the SEC Reports, the Company and its subsidiaries maintain systems

of “internal control over financial reporting” (as defined under Rules 13a-15 and 15d-15 under the Exchange Act) that comply

with the requirements of the Exchange Act and have been designed by, or under the supervision of, their respective principal executive

and principal financial officers, or persons performing similar functions, to provide reasonable assurance regarding the reliability

of financial reporting and the preparation of financial statements for external purposes in accordance with GAAP, including, but not

limited to, internal accounting controls sufficient to provide reasonable assurance that (i) transactions are executed in accordance

with management’s general or specific authorizations; (ii) transactions are recorded as necessary to permit preparation of financial

statements in conformity with GAAP and to maintain asset accountability; (iii) access to assets is permitted only in accordance with

management’s general or specific authorization; (iv) the recorded accountability for assets is compared with the existing assets

at reasonable intervals and appropriate action is taken with respect to any differences; and (v) the interactive data in eXtensible Business

Reporting Language included or incorporated by reference in the SEC Reports fairly present the information called for in all material

respects and are prepared in accordance with the Commission’s rules and guidelines applicable thereto. Since the date of the latest

audited financial statements included in the SEC Reports, there has been no change in the Company’s internal control over financial

reporting that has materially affected, or is reasonably likely to materially affect, the Company’s internal control over financial

reporting.

(hh)

ERISA. The Company, its subsidiaries and any “employee benefit plan” (as defined under the Employee Retirement Income

Security Act of 1974, as amended, and the regulations and published interpretations thereunder (collectively, “ERISA”)) established

or maintained by the Company, its subsidiaries or any of their “ERISA Affiliates” (as defined below) are in compliance in

all material respects with ERISA. “ERISA Affiliate” means, with respect to the Company and each of its subsidiaries, any

member of any group of organizations described in Sections 414(b),(c),(m) or (o) of the Internal Revenue Code of 1986, as amended, and

the regulations and published interpretations thereunder (the “Code”) of which the Company or any of its subsidiaries is

a member. No “reportable event” (as defined under ERISA) has occurred or is reasonably expected to occur with respect to

any “employee benefit plan” established or maintained by the Company, or any of its subsidiaries or any of their ERISA Affiliates.

No “employee benefit plan” established or maintained by the Company, any of its subsidiaries or any of their ERISA Affiliates,

if such “employee benefit plan” were terminated, would have any “amount of unfunded benefit liabilities” (as

defined under ERISA). Neither the Company nor any of its subsidiaries nor any of their ERISA Affiliates has incurred or reasonably expects

to incur any material liability under (i) Title IV of ERISA with respect to termination of, or withdrawal from, any “employee benefit

plan” or (ii) Sections 412, 4971, 4975 or 4980B of the Code. Each “employee benefit plan” established or maintained

by the Company, any of its subsidiaries or any of their ERISA Affiliates that is intended to be qualified under Section 401(a) of the

Code is so qualified and, to the knowledge of the Company, nothing has occurred, whether by action or failure to act, which would cause

the loss of such qualification.

(ii)

Contracts and Agreements. The agreements and documents described in the SEC Reports conform in all material respects to the descriptions

thereof contained therein and there are no agreements or other documents required by the Securities Act and the Exchange Act to be described

in the SEC Reports or to be filed with the Commission as exhibits to the SEC Reports, that have not been so described or filed. Each

agreement or other instrument (however characterized or described) to which the Company or any of its subsidiaries is a party or by which

it is or may be bound or affected and (i) that is referred to in the SEC Reports, or (ii) is material to the Company’s or its subsidiaries’

business, has been duly authorized and validly executed by the Company, is in full force and effect in all material respects and is enforceable

against the Company or any of its subsidiaries and, to the Company’s knowledge, the other parties thereto, in accordance with its

terms, except (x) as such enforceability may be limited by bankruptcy, insolvency, reorganization or similar laws affecting creditors’

rights generally, (y) as enforceability of any indemnification or contribution provision may be limited under the federal and state securities

laws, and (z) that the remedy of specific performance and injunctive and other forms of equitable relief may be subject to the equitable

defenses and to the discretion of the court before which any proceeding therefor may be brought. Except as disclosed in the SEC Reports,

none of such agreements or instruments has been assigned by the Company or its subsidiaries, and neither the Company, its subsidiaries

nor, to the Company’s knowledge, any other party is in default thereunder and, to the Company’s knowledge, no event has occurred

that, with the lapse of time or the giving of notice, or both, would constitute a default thereunder. To the Company’s knowledge,

performance by the Company or any of its subsidiaries of the material provisions of such agreements or instruments will not result in

a violation of any existing applicable law, rule, regulation, judgment, order or decree of any governmental agency or court, domestic

or foreign, having jurisdiction over the Company, its subsidiaries or any of their assets or businesses (each, a “Governmental

Entity”), including, without limitation, those relating to environmental laws and regulations.

(jj)

Title to Properties. Except as set forth in the SEC Reports, the Company and each of its subsidiaries have good and marketable

title in fee simple to, or have valid rights to lease or otherwise use, all items of real or personal property which are material to

the business of the Company, in each case free and clear of all liens, encumbrances, security interests, claims and defects that do not,

singly or in the aggregate, materially affect the value of such property and do not interfere with the use made and proposed to be made

of such property by the Company or any of its subsidiaries; and all of the leases and subleases material to the business of the Company,

and under which the Company or any of its subsidiaries hold properties described in the SEC Reports, are in full force and effect, and

neither the Company nor any of its subsidiaries has received any notice of any material claim of any sort that has been asserted by anyone

adverse to the rights of the Company or any of its subsidiaries under any of the leases or subleases mentioned above, or affecting or

questioning the rights of the Company or any of its subsidiaries to the continued possession of the leased or subleased premises under

any such lease or sublease, which would result in a Material Adverse Effect.

(kk)

No Unlawful Contributions or Other Payments. No payments or inducements have been made or given, directly or indirectly, to any

federal or local official or candidate for, any federal or state office in the United States or foreign offices by the Company, any of

its subsidiaries or any of their officers or directors, or, to the knowledge of the Company, by any of its employees or agents or any

other person in connection with any opportunity, contract, permit, certificate, consent, order, approval, waiver or other authorization

relating to the business of the Company or any of its subsidiaries, except for such payments or inducements as were lawful under applicable

laws, rules and regulations. Neither the Company, any of its subsidiaries, nor, to the knowledge of the Company, any director, officer,

agent, employee or other person associated with or acting on behalf of the Company or any of its subsidiaries, (i) has used any corporate

funds for any unlawful contribution, gift, entertainment or other unlawful expense relating to political activity; (ii) made any direct

or indirect unlawful payment to any government official or employee from corporate funds; or (iii) made any bribe, unlawful rebate, payoff,

influence payment, kickback or other unlawful payment in connection with the business of the Company.

(ll)

Foreign Corrupt Practices Act. None of the Company, any of its subsidiaries or, to the knowledge of the Company, any director,

officer, agent, employee, affiliate or other person acting on behalf of the Company or any of its subsidiaries, is aware of or has taken

any action, directly or indirectly, that would result in a violation by such persons of the Foreign Corrupt Practices Act of 1977, as

amended, and the rules and regulations thereunder (collectively, the “FCPA”), including, without limitation, making

use of the mails or any means or instrumentality of interstate commerce corruptly in furtherance of an offer, payment, promise to pay

or authorization of the payment of any money, or other property, gift, promise to give, or authorization of the giving of anything of

value to any “foreign official” (as such term is defined in the FCPA) or any foreign political party or official thereof

or any candidate for foreign political office, in contravention of the FCPA. The Company and its subsidiaries have conducted their respective

businesses in compliance with the FCPA and have instituted and maintains policies and procedures designed to ensure, and which are reasonably

expected to continue to ensure, continued compliance therewith. The foregoing representation and warranty shall also be deemed given

regarding laws of applicable non-U.S. jurisdictions similar to the FCPA, including, without limitation, Sections 291 and 291A of the

Israel Penal Law, 5737-1977 and the rules and regulations thereunder.

(mm)

Money Laundering Laws. The operations of the Company and its subsidiaries are and have been conducted at all times in compliance

with applicable financial recordkeeping and reporting requirements of the Currency and Foreign Transactions Reporting Act of 1970, as

amended, the money laundering statutes of all jurisdictions, the rules and regulations thereunder and any related or similar rules, regulations

or guidelines, issued, administered or enforced by any governmental agency (collectively, the “Money Laundering Laws”) and

no action, suit or proceeding by or before any court or governmental agency, authority or body or any arbitrator involving the Company

or any of its subsidiaries with respect to the Money Laundering Laws is pending or, to the knowledge of the Company, threatened.

(nn)

OFAC. None of the Company, any of its subsidiaries or, to the knowledge of the Company, any director, officer, agent, employee,

affiliate or person acting on behalf of the Company or any of its subsidiaries is currently subject to any U.S. sanctions administered

by the Office of Foreign Assets Control of the U.S. Treasury Department (“OFAC”); and the Company will not directly

or indirectly use the proceeds of the offering, or lend, contribute or otherwise make available such proceeds to any subsidiary, joint

venture partner or other person or entity, for the purpose of financing the activities of any person currently subject to any U.S. sanctions

administered by OFAC.

(oo)

Exchange Listing. The Common Shares are registered pursuant to Section 12(b) of the Exchange Act and are currently listed on the

Trading Market under the trading symbol “PLUR”. Except as disclosed in the SEC Reports, there is no action pending by the

Company or, to the Company’s knowledge, the Trading Market to delist the Common Shares from the Trading Market, nor has the Company

received any notification that the Trading Market is currently contemplating terminating such listing, except as otherwise disclosed

in the SEC Reports. The Company has no intention to delist the Common Shares from the Trading Market or to deregister the Common Shares

under the Exchange Act. The Company shall file, to the extent required, (i) with the Nasdaq a Supplemental Listing Application for the

listing of the Common Shares and the Warrant shares as contemplated in this Agreement, and (ii) with the Tel Aviv Stock Exchange an application

for the listing of the Common Shares and the Warrant Shares as contemplated in this Agreement. The issuance and sale of the Securities

under this Agreement does not contravene the rules and regulations of the Trading Market.

(pp)

Margin Rules. The Company owns no “margin securities” as that term is defined in Regulation U of the Board of Governors

of the Federal Reserve System (the “Federal Reserve Board”), and none of the proceeds from the issuance, sale and

delivery of the Securities as contemplated by this Agreement and as described in the SEC Reports will be used, directly or indirectly,

for the purpose of purchasing or carrying any margin security, for the purpose of reducing or retiring any indebtedness which was originally

incurred to purchase or carry any margin security or for any other purpose which might cause any of the Common Shares to be considered

a “purpose credit” within the meanings of Regulation T, U or X of the Federal Reserve Board.

(qq)

Board of Directors. The qualifications of the persons serving as board members of the Company and the overall composition of the

Company’s Board of Directors comply with the applicable requirements of the Exchange Act and the Sarbanes-Oxley Act and the listing

rules of the Exchange applicable to the Company. At least one member of the Audit Committee of the Board of Directors of the Company

qualifies as an “audit committee financial expert,” as such term is defined under Regulation S-K and the listing rules of

the Exchange. In addition, at least a majority of the persons serving on the Board of Directors of the Company qualify as “independent,”

as defined under the listing rules of the Exchange.

(rr)

No Integration. Neither the Company, nor any of its affiliates, nor any person acting on its or their behalf has, directly or

indirectly, made any offers or sales of any security or solicited any offers to buy any security, under circumstances that would cause

the offer and sale of the Securities hereunder to be integrated with prior offerings by the Company for purposes of the Securities Act

that would require the registration of the Securities or any such other securities under the Securities Act.

(ss)

No Material Defaults. Neither the Company nor any of its subsidiaries has defaulted on any installment on indebtedness for borrowed

money or on any rental on one or more long-term leases, which defaults, individually or in the aggregate, could reasonably be expected

to result in a Material Adverse Effect. The Company has not filed a report pursuant to Section 13(a) or 15(d) of the Exchange Act since

the filing of its last Annual Report on Form 10-K, indicating that it (i) has failed to pay any dividend or sinking fund installment

on preferred shares or (ii) has defaulted on any installment on indebtedness for borrowed money or on any rental on one or more long-term

leases, which defaults, individually or in the aggregate, could reasonably be expected to result in a Material Adverse Effect.

(tt)

Books and Records. The minute books of the Company and each of its subsidiaries (i) contain a substantially complete summary of

all meetings and material actions of the board of directors (including each board committee) and shareholders of the Company (or analogous

governing bodies and interest holders, as applicable) and each of its subsidiaries since the time of its respective incorporation or

organization through the date of the latest meeting and action, and (ii) accurately reflects in all material respects all transactions

referred to in such minutes.

(uu)

Regulations. The disclosures in the SEC Reports concerning the effects of federal, state, local and all foreign regulation on

the Company’s business in the past and as currently contemplated are correct in all material respects and no other such regulations

are required to be disclosed in the SEC Reports which are not so disclosed.

(vv)

Regulatory Matters; Compliance. The material terms of all preclinical and other nonclinical studies and clinical trials conducted

by or on behalf of the Company that are material to the Company have been adequately described in the SEC Reports, in all material respects.

The clinical trials and nonclinical studies conducted by or on behalf of the Company that are described in the SEC Reports or the results

of such trials and studies which are referred to in the SEC Reports were and, if still ongoing, are being conducted in material compliance

with all laws and regulations applicable thereto in the jurisdictions in which they are being conducted. The descriptions in the SEC

Reports of the results of such trials and studies are accurate and complete in all material respects and fairly present the data derived

from such trials and studies, and the Company has no knowledge of any clinical trials the aggregate results of which are inconsistent

with or otherwise call into question the results of any clinical trial conducted by or on behalf of the Company that are described in

the SEC Reports or the results of which are referred to in the SEC Reports. Except as disclosed in the SEC Reports, the Company has not

received any written notices or other communications from the FDA, the European Medicines Agency (“EMA”) or any other

governmental agency or authority imposing, requiring, requesting or suggesting a clinical hold, termination, suspension or material modification

of any clinical trial that is described in the SEC Reports or the results of which are referred to in the SEC Reports. Except as disclosed

in the SEC Reports, the Company has not received any written notices or other communications from the FDA, the EMA or any other governmental

agency, and otherwise has no knowledge of, or reason to believe that, (i) any investigational new drug application for a potential product

of the Company is or has been rejected or determined to be non-approvable or conditionally approvable; and (ii) any license, approval,

permit or authorization to conduct any clinical trial of any potential product of the Company has been, will be or may be suspended,

revoked, modified or limited.

(ww)

Information Technology. The Company’s information technology assets and equipment, computers, systems, networks, hardware,

software, websites, applications, and databases (collectively, “IT Systems”) are adequate for, and operate and perform

in all material respects as required in connection with, the operation of the business of the Company as currently conducted, except

where such failure to operate and perform would not reasonably be expected to result in a Material Adverse Effect, and to the knowledge

of the Company are free and clear of all material bugs, errors, defects, Trojan horses, time bombs, malware and other corruptants. The

Company has implemented and maintained commercially reasonable controls, policies, procedures, and safeguards to maintain and protect

their material confidential information and the integrity, continuous operation, redundancy and security of all IT Systems and data (including

all personal, personally identifiable, sensitive, confidential or regulated data (“Personal Data”)) used in connection

with their businesses, and except as would not, individually or in the aggregate, result in a Material Adverse Effect, there have been

no breaches, violations, outages or unauthorized uses of or accesses to same, except for those that have been remedied without material

cost or liability or the duty to notify any other person, nor any incidents under internal review or investigations relating to the same.

The Company is presently in compliance in all material respects with all applicable laws or statutes and all applicable judgments, orders,

rules and regulations of any court or arbitrator or governmental or regulatory authority, internal policies and contractual obligations

relating to the privacy and security of IT Systems and Personal Data and to the protection of such IT Systems and Personal Data from

unauthorized use, access, misappropriation or modification, except for any such noncompliance that would not result in a Material Adverse

Effect. The disclosures in the SEC Reports concerning the effects of federal, state, local and all foreign regulation on the Company’s

business in the past and as currently contemplated are correct in all material respects and no other such regulations are required to

be disclosed in the SEC Reports which are not so disclosed. The Company has taken all reasonably necessary actions to comply materially

with the European Union General Data Protection Regulation and all other applicable laws and regulations with respect to Personal Data

that have been announced as of the date hereof as becoming effective within 12 months after the date hereof, and for which any non-compliance

with same would be reasonably likely to create a material liability.

(xx)

Confidentiality and Non-Competition. To the Company’s knowledge, no director, officer, key employee or consultant of the

Company is subject to any confidentiality, non-disclosure, non-competition agreement or non-solicitation agreement with any employer

or prior employer that could reasonably be expected to materially affect his ability to be and act in his respective capacity of the

Company or be expected to result in a Material Adverse Effect.

(yy)

All Necessary Permits, etc. The Company and each of its subsidiaries holds, and is in compliance with, all franchises, grants,

authorizations, licenses, permits, easements, consents, certificates and orders (“Permits”) of any governmental or

self-regulatory agency, authority or body required for the conduct of its business, and all such Permits are in full force and effect.

3.2

Representations and Warranties of the Purchaser. The Purchaser

hereby represents and warrants as of the date hereof and as of the Closing Date to the Company as follows (unless as of a specific date

therein, in which case they shall be accurate as of such date):

(a)

Organization; Authority. The Purchaser is either an individual

or an entity duly incorporated or formed, validly existing and in good standing under the laws of the jurisdiction of its incorporation

or formation with full right, corporate, partnership, limited liability company or similar power and authority to enter into and to consummate

the transactions contemplated by the Transaction Documents and otherwise to carry out its obligations hereunder and thereunder. The execution

and delivery of the Transaction Documents and performance by the Purchaser of the transactions contemplated by the Transaction Documents

have been duly authorized by all necessary corporate, partnership, limited liability company or similar action, as applicable, on the

part of the Purchaser. Each Transaction Document to which it is a party has been duly executed by the Purchaser, and when delivered by

the Purchaser in accordance with the terms hereof, will constitute the valid and legally binding obligation of the Purchaser, enforceable

against it in accordance with its terms, except: (i) as limited by general equitable principles and applicable bankruptcy, insolvency,

reorganization, moratorium and other laws of general application affecting enforcement of creditors’ rights generally, (ii) as

limited by laws relating to the availability of specific performance, injunctive relief or other equitable remedies and (iii) insofar

as indemnification and contribution provisions may be limited by applicable law.

(b)

Understandings or Arrangements. The Purchaser understands that

the Securities are “restricted securities” and have not been registered under the Securities Act or any applicable state

securities law and is acquiring the Securities as principal for its own account and not with a view to or for distributing or reselling

such Securities or any part thereof in violation of the Securities Act or any applicable state securities law, has no present intention

of distributing any of such Securities in violation of the Securities Act or any applicable state securities law and has no direct or

indirect arrangement or understandings with any other persons to distribute or regarding the distribution of such Securities in violation

of the Securities Act or any applicable state securities law (this representation and warranty not limiting the Purchaser’s right

to sell the Securities in compliance with applicable federal and state securities laws). The Purchaser is acquiring the Securities hereunder

in the ordinary course of its business.

(c)

Experience of the Purchaser. The Purchaser, either alone or together

with its representatives, has such knowledge, sophistication and experience in business and financial matters so as to be capable of

evaluating the merits and risks of the prospective investment in the Securities, and has so evaluated the merits and risks of such investment.

The Purchaser is able to bear the economic risk of an investment in the Securities and, at the present time, is able to afford a complete

loss of such investment.

(d)

Access to Information. The Purchaser acknowledges that it has

had the opportunity to review the Transaction Documents (including all exhibits and schedules thereto) and the SEC Reports and has been

afforded, (i) the opportunity to ask such questions as it has deemed necessary of, and to receive answers from, representatives of the

Company concerning the terms and conditions of the offering of the Securities and the merits and risks of investing in the Securities;

(ii) access to information about the Company and its financial condition, results of operations, business, properties, management and

prospects sufficient to enable it to evaluate its investment; and (iii) the opportunity to obtain such additional information that the

Company possesses or can acquire without unreasonable effort or expense that is necessary to make an informed investment decision with

respect to the investment

(e)

Certain Transactions and Confidentiality. Other than consummating

the transactions contemplated hereunder, the Purchaser has not, nor has any Person acting on behalf of or pursuant to any understanding

with the Purchaser, directly or indirectly executed any purchases or sales, including Short Sales, of the securities of the Company during

the period commencing as of the time that the Purchaser first received a term sheet (written or oral) from the Company or any other Person

representing the Company setting forth the material terms of the transactions contemplated hereunder and ending immediately prior to

the execution hereof.

(f)

Non-Interference with Company’s Business. The Purchaser

has reviewed the SEC Reports, is familiar with the Company’s business, has no intention to act to change the Company’s business

and will not be acting to change the Company’s business without the consent of the Company’s board of directors.

(g)

Purchaser Status. At the time the Purchaser was offered the Securities,

it was, and as of the date hereof it is, and on each date on which it exercises any Warrants, it will be a “non-US person”

as defined in Regulation S (“Regulation S”) as promulgated under the Securities Act and/or an “accredited investor”

as defined in Rule 501(a)(1), (a)(2), (a)(3), (a)(7) or (a)(8) under the Securities Act.

(h)

General Solicitation. The Purchaser is not purchasing the Securities

as a result of any advertisement, article, notice or other communication regarding the Securities published in any newspaper, magazine

or similar media or broadcast over television or radio or presented at any seminar or, to the knowledge of the Purchaser, any other general

solicitation or general advertisement.

(i)

Purchaser reporting obligations. Purchaser acknowledges that as

a result of the purchase of the Shares, Purchaser may be subject to the reporting obligations of Section 13 and Section 16 of the Exchange

Act, and Purchaser agrees to comply with all such reporting obligations in a timely manner.

The

Company acknowledges and agrees that the representations contained in this Section 3.2 shall not modify, amend or affect the Purchaser’s

right to rely on the Company’s representations and warranties contained in this Agreement or any representations and warranties

contained in any other Transaction Document or any other document or instrument executed and/or delivered in connection with this Agreement

or the consummation of the transactions contemplated hereby. Notwithstanding the foregoing, for the avoidance of doubt, nothing contained

herein shall constitute a representation or warranty, or preclude any actions.

ARTICLE

IV.

OTHER

AGREEMENTS OF THE PARTIES

4.1

Transfer Restrictions.

(a)

The Securities may only be disposed of in compliance with U.S. state and U.S. federal securities laws. In connection with any transfer

of Securities other than pursuant to an effective Registration Statement (as contemplated by Section 4.10 or otherwise) or Rule 144,

to the Company or to an Affiliate of a Purchaser or in connection with a pledge as contemplated in Section 4.1(b), the Company may require

the transferor thereof to provide to the Company an opinion of counsel selected by the transferor and reasonably acceptable to the Company,

the form and substance of which opinion shall be reasonably satisfactory to the Company, to the effect that such transfer does not require

registration of such transferred Securities under the Securities Act. As a condition of transfer, any such transferee shall agree in

writing to be bound by the terms of this Agreement and shall have the rights and obligations of a Purchaser under this Agreement.

(b)

The Purchaser agrees to the imprinting, so long as required by this Section 4.1, of a legend on the Securities substantially in the following

form (in addition to any legend required by applicable state securities or “blue sky” laws):

“[NEITHER]

THIS SECURITY [NOR THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE] HAS [NOT] BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933,

AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAWS AND MAY NOT BE SOLD, TRANSFERRED OR OTHERWISE DISPOSED

OF UNLESS REGISTERED UNDER THE SECURITIES ACT AND UNDER APPLICABLE STATE SECURITIES LAWS OR THE COMPANY SHALL HAVE RECEIVED AN OPINION

OF COUNSEL THAT REGISTRATION OF SUCH SECURITIES [AND THE SECURITIES ISSUABLE UPON EXERCISE OF THIS SECURITY] UNDER THE SECURITIES ACT

AND UNDER THE PROVISIONS OF APPLICABLE STATE SECURITIES LAWS IS NOT REQUIRED.”

Each

certificate representing the Securities, if such securities are being offered to the Purchaser in reliance upon Regulation S, shall be

stamped or otherwise imprinted with a legend substantially in the following form (in addition to any legend required by applicable state

securities or “blue sky” laws):

“[NEITHER]

THIS SECURITY [NOR THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE] HAS [NOT] BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933,

AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAWS AND NEITHER SUCH SECURITIES [AND THE SECURITIES ISSUABLE

UPON EXERCISE OF THIS SECURITY] NOR ANY INTEREST THEREIN MAY BE OFFERED, SOLD, PLEDGED, ASSIGNED OR OTHERWISE TRANSFERRED EXCEPT (1)

IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S PROMULGATED UNDER THE SECURITIES ACT, AND BASED ON AN OPINION OF COUNSEL, WHICH COUNSEL

AND OPINION ARE REASONABLY SATISFACTORY TO THE COMPANY, THAT THE PROVISIONS OF REGULATION S HAVE BEEN SATISFIED, (2) PURSUANT TO AN EFFECTIVE

REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS OR (3) PURSUANT TO AN AVAILABLE EXEMPTION FROM THE

REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS, IN WHICH CASE THE HOLDER MUST, PRIOR TO SUCH TRANSFER,

FURNISH TO THE COMPANY AN OPINION OF COUNSEL, WHICH COUNSEL AND OPINION ARE REASONABLY SATISFACTORY TO THE COMPANY, THAT SUCH SECURITIES

[OR THE SECURITIES ISSUABLE UPON EXERCISE OF THIS SECURITY] MAY BE OFFERED, SOLD, PLEDGED, ASSIGNED OR OTHERWISE TRANSFERRED IN THE MANNER

CONTEMPLATED PURSUANT TO AN AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND APPLICABLE STATE SECURITIES

LAWS. HEDGING TRANSACTIONS INVOLVING THE SECURITIES REPRESENTED BY THIS CERTIFICATE MAY NOT BE CONDUCTED UNLESS IN COMPLIANCE WITH THE

SECURITIES ACT.”

4.2

Securities Laws Disclosure; Publicity. The Company (a) shall,

by the Disclosure Time issue a press release disclosing the material terms of the transactions contemplated hereby, and (b) shall file

a Current Report on Form 8-K, including the Transaction Documents as exhibits thereto, with the Commission within the time required by

the Exchange Act. Purchaser shall be afforded the right to review and comment on the draft press release and Form 8-K sufficiently in

advance of the Disclosure Time, and, subject to applicable law, the Company shall favorably consider including all comments provided

by Purchaser. From and after the issuance of such press release, the Company represents to the Purchaser that it shall have publicly

disclosed all material, non-public information delivered to the Purchaser by the Company or any of its Subsidiaries, or any of their

respective officers, directors, employees or agents in connection with the transactions contemplated by the Transaction Documents. In

addition, effective upon the issuance of such press release, the Company acknowledges and agrees that any and all confidentiality or

similar obligations under any agreement, whether written or oral, between the Company, any of its Subsidiaries or any of their respective

officers, directors, agents, employees or Affiliates on the one hand, and the Purchaser or any of its Affiliates on the other hand, shall

terminate. The Company and the Purchaser shall consult with each other in issuing any other press releases with respect to the transactions

contemplated hereby, and neither the Company nor the Purchaser shall issue any such press release nor otherwise make any such public

statement without the prior consent of the Company, with respect to any press release of the Purchaser, or without the prior consent

of the Purchaser, with respect to any press release of the Company, which consent shall not unreasonably be withheld or delayed, except

if such disclosure is required by law, in which case the disclosing party shall promptly provide the other party with prior notice of

such public statement or communication. Notwithstanding the foregoing, the Company shall not publicly disclose the name of the Purchaser,

or include the name of the Purchaser in any filing with the Commission or any regulatory agency or Trading Market, without the prior

written consent of the Purchaser, except (a) as required by federal securities law in connection with the filing of final Transaction

Documents with the Commission and (b) to the extent such disclosure is required by law or Trading Market regulations, in which case the

Company shall provide the Purchaser with prior notice of such disclosure permitted under this clause (b).

4.3

Certain Transactions and Confidentiality. The Purchaser covenants

that neither it nor any Affiliate acting on its behalf or pursuant to any understanding with it will execute any purchases or sales,

including Short Sales of any of the Company’s securities during the period commencing with the execution of this Agreement and

ending at such time that the transactions contemplated by this Agreement are first publicly announced pursuant to the initial press release

as described in Section 4.2. The Purchaser covenants that until such time as the transactions contemplated by this Agreement are publicly

disclosed by the Company pursuant to the initial press release as described in Section 4.2, the Purchaser will maintain the confidentiality

of the existence and terms of such transactions.

4.4

Form D; Blue Sky Filings. The Company agrees to timely file a

Form D, if required by applicable law, with respect to the Securities as may be required under Regulation D and to provide a copy thereof,

promptly upon request of the Purchaser. The Company shall take such action as the Company shall reasonably determine is necessary in

order to obtain an exemption for, or to qualify the Shares for sale to the Purchaser at the Closing under applicable securities or “Blue

Sky” laws of the states of the United States, if necessary, and shall provide evidence of such actions promptly upon request of

the Purchaser.

4.5

[Reserved].

4.6

Transfer Taxes. On the Closing Date, all stock transfer, stamp

or other taxes (other than income taxes) that are required to be paid in connection with the issuance, sale and delivery of the Securities

to the Purchaser hereunder will be fully paid or provided for by the Company and all laws imposing such taxes will have been fully complied

with and the Purchasers and their respective Affiliates shall have no obligation therefor.

4.7

Reservation of Common Shares. As of the date hereof, the Company

has reserved and the Company shall continue to reserve and keep available at all times, free of preemptive rights, a sufficient number

of Common Shares for the purpose of enabling the Company to issue the Warrant Shares that are issuable upon the exercise of the Warrants.

4.8

[Reserved].

4.9

Adjustments in Share Numbers and Prices. In the event of any share

split, subdivision, dividend or distribution payable in Common Shares (or other securities or rights convertible into, or entitling the

holder thereof to receive directly or indirectly Common Shares), combination or other similar recapitalization or event occurring after

the date hereof and prior to the Closing, each reference this Agreement to a number of shares or a price per share shall be deemed to

be amended to appropriately account for such event.

4.10

Rule 144 Information. The Company shall use its reasonable best

efforts to timely file all reports required under the Exchange Act so as to enable the Purchaser to sell the Shares and Warrant Shares

pursuant to Rule 144, if applicable. .

ARTICLE

MISCELLANEOUS

5.1

Termination. This Agreement may be terminated by the Company or

the Purchaser by written notice to the other party, if the Closing has not been consummated on or before December 24, 2025; provided,

however, that no such termination will affect the right of any party to sue for any breach by any other party (or parties).

5.2

Fees and Expenses. The Company shall pay all Transfer Agent fees

(including, without limitation, any fees required for same-day processing of any instruction letter delivered by the Company and any

exercise notice delivered by a Purchaser), fees and expenses in connection with the TASE and Nasdaq listing, stamp taxes and other taxes

and duties levied in connection with the delivery of any Securities to the Purchaser.

5.3

Entire Agreement. The Transaction Documents, together with the

exhibits and schedules thereto, contain the entire understanding of the parties with respect to the subject matter hereof and thereof

and supersede all prior agreements and understandings, oral or written, with respect to such matters, which the parties acknowledge have

been merged into such documents, exhibits and schedules.

5.4

Notices. Any and all notices or other communications or deliveries

required or permitted to be provided hereunder shall be in writing and shall be deemed given and effective on the earliest of: (a) the

time of transmission, if such notice or communication is delivered via email attachment at the email address as set forth on the signature

pages attached hereto at or prior to 5:30 p.m. (New York City time) on a Trading Day, (b) the next Trading Day after the time of transmission,

if such notice or communication is delivered via facsimile at the facsimile number or email attachment at the email address as set forth

on the signature pages attached hereto on a day that is not a Trading Day or later than 5:30 p.m. (New York City time) on any Trading

Day, (c) the second (2nd) Trading Day following the date of mailing, if sent by U.S. nationally recognized overnight courier

service or (d) upon actual receipt by the party to whom such notice is required to be given. The address for such notices and communications

shall be as set forth on the signature pages attached hereto. To the extent that any notice provided pursuant to any Transaction Document

constitutes, or contains, material, non-public information regarding the Company or any Subsidiaries, the Company shall simultaneously

file such notice with the Commission pursuant to a Current Report on Form 8-K.

5.5

Amendments; Waivers. No provision of this Agreement may be waived,

modified, supplemented or amended except in a written instrument signed, in the case of an amendment, by the Company and the Purchaser.

No waiver of any default with respect to any provision, condition or requirement of this Agreement shall be deemed to be a continuing

waiver in the future or a waiver of any subsequent default or a waiver of any other provision, condition or requirement hereof, nor shall

any delay or omission of any party to exercise any right hereunder in any manner impair the exercise of any such right. Any amendment

effected in accordance with this Section 5.5 shall be binding upon the Purchaser and holder of Securities and the Company.

5.6

Headings. The headings herein are for convenience only, do not

constitute a part of this Agreement and shall not be deemed to limit or affect any of the provisions hereof.

5.7

Successors and Assigns. This Agreement shall be binding upon and

inure to the benefit of the parties and their successors and permitted assigns. The Company may not assign this Agreement or any rights

or obligations hereunder without the prior written consent of the Purchaser (other than by merger). The Purchaser may assign any or all

of its rights under this Agreement to any Person to whom the Purchaser assigns or transfers any Securities, provided that such transferee

agrees in writing to be bound, with respect to the transferred Securities, by the provisions of the Transaction Documents that apply

to the Purchaser.

5.8

No Third-Party Beneficiaries. This Agreement is intended for the

benefit of the parties hereto and their respective successors and permitted assigns and is not for the benefit of, nor may any provision

hereof be enforced by, any other Person, except as otherwise set forth in this Section 5.8.

5.9

Governing Law. All questions concerning the construction, validity,

enforcement and interpretation of the Transaction Documents shall be governed by and construed and enforced in accordance with the internal

laws of the State of New York, without regard to the principles of conflicts of law thereof. Each party agrees that all legal proceedings

concerning the interpretations, enforcement and defense of the transactions contemplated by this Agreement and any other Transaction

Documents (whether brought against a party hereto or its respective affiliates, directors, officers, shareholders, partners, members,

employees or agents) shall be commenced exclusively in the state and federal courts sitting in the City of New York. Each party hereby

irrevocably submits to the exclusive jurisdiction of the state and federal courts sitting in the City of New York, Borough of Manhattan

for the adjudication of any dispute hereunder or in connection herewith or with any transaction contemplated hereby or discussed herein

(including with respect to the enforcement of any of the Transaction Documents), and hereby irrevocably waives, and agrees not to assert

in any action or proceeding, any claim that it is not personally subject to the jurisdiction of any such court, that such action or proceeding

is improper or is an inconvenient venue for such proceeding. Each party hereby irrevocably waives personal service of process and consents

to process being served in any such action or proceeding by mailing a copy thereof via registered or certified mail or overnight delivery

(with evidence of delivery) to such party at the address in effect for notices to it under this Agreement and agrees that such service

shall constitute good and sufficient service of process and notice thereof. Nothing contained herein shall be deemed to limit in any

way any right to serve process in any other manner permitted by law. If any party shall commence an action or proceeding to enforce any

provisions of the Transaction Documents, then the prevailing party in such action or proceeding shall be reimbursed by the non-prevailing

party for its reasonable attorneys’ fees and other costs and expenses incurred with the investigation, preparation and prosecution

of such action or proceeding.

5.10

Survival. The representations and warranties of the Purchaser

and the agreements and covenants contained herein shall survive the Closing and the delivery of the Shares for a period of two (2) years

from the Closing. The agreements and covenants contained herein shall survive for the applicable statute of limitations.

5.11

Execution. This Agreement may be executed in two or more counterparts,

all of which when taken together shall be considered one and the same agreement and shall become effective when counterparts have been

signed by each party and delivered to each other party, it being understood that the parties need not sign the same counterpart. In the

event that any signature is delivered by facsimile transmission or by e-mail delivery of a “.pdf” format data file, such

signature shall create a valid and binding obligation of the party executing (or on whose behalf such signature is executed) with the

same force and effect as if such facsimile or “.pdf” signature page were an original thereof.

5.12

Severability. If any term, provision, covenant or restriction

of this Agreement is held by a court of competent jurisdiction to be invalid, illegal, void or unenforceable, the remainder of the terms,

provisions, covenants and restrictions set forth herein shall remain in full force and effect and shall in no way be affected, impaired

or invalidated, and the parties hereto shall use their commercially reasonable efforts to find and employ an alternative means to achieve

the same or substantially the same result as that contemplated by such term, provision, covenant or restriction. It is hereby stipulated

and declared to be the intention of the parties that they would have executed the remaining terms, provisions, covenants and restrictions

without including any of such that may be hereafter declared invalid, illegal, void or unenforceable.

5.13

Independent Nature of Purchaser’s Obligations and Rights.

Nothing contained herein or in any other Transaction Document, and no action taken by the Purchaser pursuant hereto or thereto, shall

be deemed to constitute the Purchaser as a partnership, an association, a joint venture or any other kind of entity, or create a presumption

that the Purchaser is in any way acting in concert or as a group with respect to such obligations or the transactions contemplated by

the Transaction Documents. The Purchaser shall be entitled to independently protect and enforce its rights including, without limitation,

the rights arising out of this Agreement or out of the other Transaction Documents. The Purchaser has been represented by its own separate

legal counsel in its review and negotiation of the Transaction Documents.

5.14

Fridays, Satrudays, Sundays, Holidays, etc. If the last or appointed

day for the taking of any action or the expiration of any right required or granted herein shall not be a Business Day, then such action

may be taken or such right may be exercised on the next succeeding Business Day.

5.15

Construction. The parties agree that each of them and/or their

respective counsel have reviewed and had an opportunity to revise the Transaction Documents and, therefore, the normal rule of construction

to the effect that any ambiguities are to be resolved against the drafting party shall not be employed in the interpretation of the Transaction

Documents or any amendments thereto. In addition, each and every reference to share prices and Common Shares in any Transaction Document

shall be subject to adjustment for reverse and forward share splits, share dividends, share combinations and other similar transactions

of the Common Shares that occur after the date of this Agreement.

5.16

WAIVER OF JURY TRIAL. IN ANY ACTION, SUIT, OR PROCEEDING IN ANY JURISDICTION BROUGHT BY ANY PARTY AGAINST

ANY OTHER PARTY, THE PARTIES EACH KNOWINGLY AND INTENTIONALLY, TO THE GREATEST EXTENT PERMITTED BY APPLICABLE LAW, HEREBY ABSOLUTELY,

UNCONDITIONALLY, IRREVOCABLY AND EXPRESSLY WAIVES FOREVER TRIAL BY JURY.

(Signature

Pages Follow)

WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized

signatories as of the date first indicated above.

PLURI INC.

Address for Notice:

MATAM Advanced Technology

Park Building No. 5

Haifa, Israel 3508409

By:

/s/Yaky Yanay

E-mail:

Name:

Yaky Yanay

Title:

Chief Executive Officer

By:

/s/ Liat Zalts

E-mail:

Name:

Liat Zalts

Title:

Chief Financial Officer

[REMAINDER

OF PAGE INTENTIONALLY LEFT BLANK

SIGNATURE PAGE FOR PURCHASER FOLLOWS]

[PURCHASER

SIGNATURE PAGES TO SECURITIES PURCHASE AGREEMENT]

WITNESS WHEREOF, the undersigned have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories

as of the date first indicated above.

U.S.

Domestic Purchaser (please check): ☐

Non-U.S.

Purchaser (please check): ☒

Name of Purchaser: Chutzpah Holdings LP

Signature of Authorized Signatory of Purchaser:

/s/ Alexandre Weinstein

Name of Authorized Signatory:

Alexandre Weinstein

Title of Authorized Signatory:

Email Address of Authorized Signatory:

Address for Notice to Purchaser:

337 WINSTON ROAD OAKVILLE

Ontario (CA-ON), L6L

4W6 CANADA

Subscription Amount:

$2,500,000

Number of Shares:

625,000

Common Warrant:

625,000

EIN Number (for U.S. Domestic Purchaser):____________________

Exhibit

FORM

OF WARRANT

Exhibit

B-1

Accredited

Investor Questionnaire (U.S. investor only)

The

undersigned understands that the representations contained below are made for the purpose of qualifying him or her as an “accredited

investor” as that term is defined in Regulation D of the General Rules and Regulations promulgated under the Securities Act of

1933, as amended (the “Act”), and for the purpose of inducing a sale of the securities to him or her. The undersigned hereby

represents that the statement or statements initialed below are true and correct in all respects. The undersigned understands that a

false representation may constitute a violation of law, and that any person who suffers damage as a result of a false representation

may have a claim against the undersigned for damages.

(a) Accredited

individual investors must initial at least one of the following statements:

(1) I

certify that I am an accredited investor because I had individual income in excess of $200,000

in each of the two most recent years or joint income with my spouse or spousal equivalent

in excess of $300,000 in each of those years and have a reasonable expectation of reaching

the same income level in the current year;

(2) I

certify that I am an accredited investor because I have an my individual net worth, or joint

net worth with my spouse and I have an individual net worth or spousal equivalent, in excess

of exceeds $1,000,000. For purposes of calculating net worth under this paragraph my primary

residence is not included as an asset; indebtedness that is secured by my primary residence,

up to the estimated fair market value of the primary residence at the time of the sale of

securities, is not be included as a liability (except that if the amount of such indebtedness

outstanding at the time of sale of securities exceeds the amount outstanding 60 days before

such time, other than as a result of the acquisition of the primary residence, the amount

of such excess is included as a liability); and indebtedness that is secured by my primary

residence in excess of the estimated fair market value of the primary residence at the time

of the sale of securities is included as a liability.

(3) I

certify that I am an accredited investor because I am a director or executive officer of

Pluri Inc.

(4) I

hold one of the following licenses in good standing: General Securities Representative license

(Series 7), the Private Securities Offerings Representative license (Series 82), or the Investment

Adviser Representative license (Series 65).

(b) Accredited

partnerships, corporations or other entities must initial one or more of the following statements:

(1) The

undersigned hereby certifies that all of the beneficial equity owners of the undersigned

qualify as accredited individual investors under items (a)(1) to (a)(4) above or (b)(2) to

(b)(11) below;

(2) The

undersigned is a bank as defined in section 3(a)(2) of the Act, or any savings and loan association

or other institution as defined in section 3(a)(5)(A) of the Act whether acting in its individual

or fiduciary capacity;

(3) The

undersigned is a broker or dealer registered pursuant to section 15 of the Securities Exchange

Act of 1934, as amended;

(4) The

undersigned is an investment adviser registered pursuant to section 203 of the Investment

Advisers Act of 1940, as amended, or registered pursuant to the laws of a state;

(5) The

undersigned is an investment adviser relying on the exemption from registering with the Securities

and Exchange Commission under section 203(l) or (m) of the Investment Advisers Act of 1940,

as amended;

(6) The

undersigned is an insurance company as defined in section 2(a)(13) of the Act;

(7) The

undersigned is an investment company registered under the Investment Company Act of 1940,

as amended or a business development company as defined in section 2(a)(48) of that Act;

(8) The

undersigned is a Small Business Investment Company licensed by the U.S. Small Business Administration

under section 301(c) or (d) of the Small Business Investment Act of 1958, as amended;

(9) The

undersigned is a Rural Business Investment Company as defined in section 384A of the Consolidated

Farm and Rural Development Act;

(10) The

undersigned is a plan established and maintained by a state, its political subdivisions,

or any agency or instrumentality of a state or its political subdivisions, for the benefit

of its employees, if such plan has total assets in excess of $5,000,000;

(11) The

undersigned is an employee benefit plan within the meaning of Title I of the Employee Retirement

Income Security Act of 1974 and either (check one or more, as applicable):

(a) the

investment decision is made by a plan fiduciary, as defined therein, in Section 3(21), which

is either a bank, savings and loan association, insurance company, or registered investment

adviser; or

(b) the

employee benefit plan has total assets in excess of $5,000,000; or

plan is a self-directed plan with investment decisions made solely by persons who are “accredited

investors” as defined therein.

(12) The

undersigned is a private business development company as defined in Section 202(a)(22) of

the Investment Advisers Act of 1940, as amended.

(13) The

undersigned has total assets in excess of $5,000,000, was not formed for the specific purpose

of acquiring the securities offered and is one or more of the following (check one or more,

as appropriate):

(a) an

organization described in Section 501(c)(3) of the Internal Revenue Code of 1986, as amended;

(b) a corporation,

partnership or limited liability company;

Massachusetts or similar business trust, or

(d) a

limited liability company.

(14) The

undersigned is a trust with total assets exceeding $5,000,000, which was not formed for the

specific purpose of acquiring the securities offered and whose purchase is directed by a

person who has such knowledge and experience in financial and business matters that he or

she is capable of evaluating the merits and risks of the investment in the securities offered.

(15) The

undersigned is an entity, of a type not listed in paragraphs (b)(1) to (b)(14), not formed

for the specific purpose of acquiring the securities offered, owning investments in excess

of $5,000,000.

(16) The

undersigned is a “family office,” as defined in rule 202(a)(11)(G)-1 under the

Investment Advisers Act of 1940 (17 CFR 275.202(a)(11)(G)-1): (i) with assets under management

in excess of $5,000,000, (ii) that is not formed for the specific purpose of acquiring the

securities offered, and (iii) whose prospective investment is directed by a person who has

such knowledge and experience in financial and business matters that such family office is

capable of evaluating the merits and risks of the prospective investment.

(17) The

undersigned is a “family client,” as defined in rule 202(a)(11)(G)-1 under the

Investment Advisers Act of 1940 (17 CFR 275.202(a)(11)(G)-1)), of a family office meeting

the requirements in paragraph (b)(15) above and whose prospective investment in the issuer

is directed by such family

[Signature

page follows]

Date:____________,

2026

SIGNATURE FOR INDIVIDUAL:

SIGNATURE FOR PARTNERSHIP,

CORPORATION, TRUST OR OTHER ENTITY:

(signature)

(Print Name)

(Signature of Authorized Signatory)

(Signature of any joint tenant or co-holder of any security issued by

Pluri Inc)

(Name of Authorized Signatory)

(Print Name)

(Title)

Exhibit

B-2

Regulation

S Questionnaire (Non-U.S. investor only)

The

information contained herein is being furnished to the Company in order for the Pluri Inc. (the “Company”) to determine whether

the undersigned’s subscription for Securities may be accepted pursuant to Rule 903 of Regulation S promulgated under the Securities

Act of 1933, as amended (the “Securities Act”). The undersigned understands that (i) the Company will rely upon the following

information for purposes of complying with Federal and applicable state securities laws, (ii) the Securities will not be registered under

the Securities Act in reliance upon the exemption from registration provided by Rule 903 of Regulation S of the Securities Act, and (iii)

this representation letter is not an offer to sell nor the solicitation of an offer to buy any Securities, or any other securities, to

the undersigned.

1. At

the time of (a) the offer by the Company and (b) the acceptance of the offer by such person or entity, of the Securities, such person

or entity was outside the United States.

2. Such

person or entity is acquiring the Securities for such Purchaser’s own account, for investment and not for distribution or resale

to others and is not purchasing the Securities for the account or benefit of any U.S. person, or with a view towards distribution to

any U.S. person, in violation of the registration requirements of the Securities Act.

3. Such

person or entity will make all subsequent offers and sales of the Securities either (x) outside of the United States in compliance with

Regulation S; (y) pursuant to a registration under the Securities Act; or (z) pursuant to an available exemption from registration under

the Securities Act. Specifically, such person or entity will not resell the Securities to any U.S. person or within the United States

prior to the expiration of a period commencing on the Closing Date and ending on the date that is one year thereafter (the “Distribution

Compliance Period”), except pursuant to registration under the Securities Act or an exemption from registration under the Securities

Act.

4. Such

person or entity has no present plan or intention to sell the Securities in the United States or to a U.S. person at any predetermined

time, has made no predetermined arrangements to sell the Securities and is not acting as a distributor of such securities.

5. Neither

such person or entity, its affiliates nor any person acting on behalf of such person or entity, has entered into, has the intention of

entering into, or will enter into any put option, short position or other similar instrument or position in the U.S. with respect to

the Securities at any time after the Closing Date through the Distribution Compliance Period except in compliance with the Securities

Act.

6. Such

person or entity consents to the placement of a restrictive legend on any certificate or other document evidencing the Securities, relating

to the fact that the Securities are not registered under the Securities Act.

7. Such

person or entity is not acquiring the Securities in a transaction (or an element of a series of transactions) that is part of any plan

or scheme to evade the registration provisions of the Securities Act.

8. Such

person or entity has sufficient knowledge and experience in finance, securities, investments and other business matters to be able to

protect such person’s or entity’s interests in connection with the transactions contemplated by this Agreement.

9. Such

person or entity has consulted, to the extent that it has deemed necessary, with its tax, legal, accounting and financial advisors concerning

its investment in the Securities.

10. Such

person or entity understands the various risks of an investment in the Securities and can afford to bear such risks for an indefinite

period of time, including, without limitation, the risk of losing its entire investment in the Securities.

11. Such

person or entity has had access to the Company’s publicly filed reports with the Securities and Exchange Commission and has been

furnished with all other public information regarding the Company that such person or entity has requested and all such public information

is sufficient for such person or entity to evaluate the risks of investing in the Securities.

12. Such

person or entity has been afforded the opportunity to ask questions of and receive answers concerning the Company and the terms and conditions

of the issuance of the Securities.

13. Such

person or entity is not relying on any representations and warranties concerning the Company made by the Company or any officer, employee

or agent of the Company, other than those contained in this Agreement.

14. Such

person or entity will not sell or otherwise transfer the Securities unless either (A) the transfer of such securities is registered under

the Securities Act or (B) an exemption from registration of such securities is available.

15. Such

person or entity understands and acknowledges that the Securities have not been recommended by any federal or state securities commission

or regulatory authority, that the foregoing authorities have not confirmed the accuracy or determined the adequacy of any information

concerning the Company that has been supplied to such person or entity and that any representation to the contrary is a criminal offense.

[signature

page follows]

Date: March 24, 2026

SIGNATURE FOR INDIVIDUAL:

SIGNATURE FOR PARTNERSHIP, CORPORATION, TRUST OR OTHER ENTITY:

Chutzpah Holdings LP

(Signature)

(Print Name)

/s/ Alexandre Weinstein

(Print Name)

(Signature of Authorized Signatory)

Alexandre Weinstein

(Signature of any joint tenant or co-holder of any security issued by Pluri Inc.)

(Name of Authorized Signatory)

(Print Name)

(Title)

Schedule

3.1(o)

Company Capitalization

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Reference 1: http://www.xbrl.org/2003/role/presentationRef

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Local phone number for entity.

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Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef

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Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef

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Title of a 12(b) registered security.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef

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Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.

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Trading symbol of an instrument as listed on an exchange.

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Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.

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