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Form 8-K

sec.gov

8-K — Outlook Therapeutics, Inc.

Accession: 0001104659-26-062865

Filed: 2026-05-18

Period: 2026-05-15

CIK: 0001649989

SIC: 2836 (BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES))

Item: Results of Operations and Financial Condition

Item: Financial Statements and Exhibits

Documents

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13

OR 15(d) of The Securities Exchange Act of 1934

Date of Report (Date

of earliest event reported): May 15, 2026

Outlook Therapeutics,

Inc.

(Exact name of registrant

as specified in its charter)

Delaware

001-37759

38-3982704

(State or other jurisdiction

of incorporation)

(Commission File Number)

(IRS Employer Identification No.)

111

S. Wood Avenue, Unit

#100

Iselin, New Jersey

08830

(Address of principal executive offices)

(Zip Code)

Registrant's telephone number, including area code:

(609) 619-3990

Check the appropriate box below if the Form 8-K

filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities pursuant to Section 12(b) of the Act:

Title of Each Class

Trading Symbol(s)

Name of Each Exchange

on Which

Registered

Common Stock

OTLK

The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth

company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange

Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ¨

If an emerging growth company, indicate by check mark if the registrant

has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant

to Section 13(a) of the Exchange Act. ¨

Item 2.02     Results

of Operations and Financial Condition

On May 15, 2026, Outlook

Therapeutics, Inc. (the “Company”) issued a press release announcing its financial results for its second fiscal quarter

which ended March 31, 2026. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K.

The information contained in this

Item 2.02 and in the accompanying Exhibit 99.1 shall not be deemed filed for purposes of Section 18 of the Securities Exchange Act of

1934, as amended (the “Exchange Act”), or incorporated by reference in any filing under the Exchange Act or the Securities

Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.

Item 9.01     Financial Statements and Exhibits

(d) Exhibits

Exhibit No.

Description

99.1

Press Release dated May 15, 2026

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities

Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Outlook Therapeutics, Inc.

Date: May 15, 2026

By:

/s/ Lawrence A. Kenyon

Lawrence A. Kenyon

Chief Financial Officer

EX-99.1 — EXHIBIT 99.1

EX-99.1

Filename: tm2614868d1_ex99-1.htm · Sequence: 2

Exhibit 99.1

Outlook Therapeutics

Reports Second Quarter Fiscal Year 2026 Financial Results and Provides Corporate Update

· Completed

Formal Dispute Resolution Meeting with FDA regarding Complete Response Letter (CRL) for ONS-5010; Decision Expected This Month

· Continued

expansion of LYTENAVA™ (bevacizumab gamma) in Europe with Commercial Distribution Agreement with Mediconsult AG in Switzerland

· Launched

Real-World Evidence Study in Germany to Further Strengthen the Overall Value Proposition of LYTENAVA™

ISELIN,

N.J., May 15, 2026 — Outlook Therapeutics, Inc. (Nasdaq: OTLK), a biopharmaceutical company focused on enhancing the

standard of care for bevacizumab for the treatment of retina diseases, today announced financial results for the second quarter of fiscal

year 2026 ended March 31, 2026, and provided a corporate update.

“We

remain committed to working collaboratively with the FDA to establish a clear path forward toward potential U.S. approval. Our

objective is clear: to bring the first FDA-approved ophthalmic formulation of bevacizumab to patients in the United States,” said

Bob Jahr, Chief Executive Officer of Outlook Therapeutics. “In addition, we are encouraged by the continued momentum of our European

commercial launch of LYTENAVA, highlighted by our expansion into new markets, as well as our recently announced partnership in Switzerland

and growing physician adoption in our initial launch countries.”

During the

second quarter of fiscal year 2026, Outlook Therapeutics continued to advance the commercial rollout of LYTENAVA™ (bevacizumab gamma)

in Europe. In anticipation of a potential launch in Switzerland, the Company entered into a Commercial Distribution Agreement with Mediconsult

AG for the sale and distribution of LYTENAVA™ (bevacizumab gamma) in Switzerland. As part of the agreement, Mediconsult AG will

be responsible for regulatory activities in Switzerland, including seeking and maintaining Marketing Authorization. The Company is targeting

a 2027 launch of LYTENAVA™ in Switzerland in 2027, subject to receipt of Marketing Authorization in that country.

Building

on the initial launch momentum, Outlook Therapeutics intends to expand into the Netherlands and Ireland later in 2026 and additional European

markets and beyond in 2027. As Outlook Therapeutics continues to see increasing physician adoption and demand in the initial launch countries,

the Company remains focused on executing its commercialization strategy to pursue additional launches and potential partnerships inside

and outside of Europe and further establishing LYTENAVA as a new treatment option for wet AMD.

The Company

also launched a real-world evidence study in Germany to further evaluate the performance of LYTENAVA™ in routine clinical practice

following its approval in the European Union and the United Kingdom. These data are expected to support reimbursement and market access

efforts in key European markets, inform potential regulatory interactions, and further strengthen the overall value proposition of LYTENAVA™

for physicians, patients, and stakeholders.

ONS-5010

U.S. Regulatory Update

Outlook

Therapeutics continues to advance its regulatory efforts in the United States for ONS-5010/LYTENAVA™ (bevacizumab-vikg). The Company

conducted its formal dispute resolution meeting with the U.S. Food and Drug Administration (FDA) in April 2026 and remains engaged in

the process as it awaits the formal decision from the FDA. The Company has provided a comprehensive package of clinical, functional, pharmacodynamic,

and safety data, including results from the NORSE TWO and NORSE EIGHT studies, which the Company believes support the efficacy and safety

profile of ONS-5010/LYTENAVA™ for the treatment of wet AMD. Outlook Therapeutics remains committed to working collaboratively with

the FDA to establish a clear path forward toward potential U.S. approval.

Outlook

Therapeutics expects a formal decision from the FDA in May 2026.

Financial

Highlights for the Second Fiscal Quarter Ended March 31, 2026

For the second fiscal quarter ended March 31,

2026, Outlook Therapeutics reported net loss attributable to common stockholders of $4.5 million, or $0.05 per basic and diluted share.

This compares with net loss attributable to common stockholders of $46.4 million, or $1.50 per basic and diluted share for the same period

last year.

For the fiscal quarter ended March 31, 2026, Outlook

Therapeutics reported an adjusted net loss attributable to common stockholders of $14.1 million, or $0.16 per basic and diluted share,

as compared to an adjusted net loss attributable to common stockholders of $12.4 million, or $0.40 per basic and diluted share for the

second fiscal quarter of 2025.

Adjusted net loss attributable to common stockholders for the fiscal quarter ended March 31, 2026, excludes $2.5 million of gain from

change in fair value of promissory notes, $0.3 million of gain on extinguishment of debt, and $6.8 million of gain from change in fair

value of warrant liability. Adjusted net loss attributable to common stockholders for the fiscal quarter ended March 31, 2025, excludes

$33.9 million of warrant inducement expenses, $2.1 million of gain from change in fair value of warrant liability, and $2.1 million of

loss from change in fair value of promissory notes.

Net revenue in the fiscal quarter ended March

31, 2026, was offset by recurring fixed distribution costs during the quarter. Overall, unit sales of LYTENAVA in Europe for the second

fiscal quarter of 2026 were down approximately 10% compared to the quarter ended December 31, 2025, but have trended upward early in the

current quarter. Outlook Therapeutics has taken steps to reduce costs in Europe in an effort to improve margins in future quarters.

In

March 2026, Outlook Therapeutics reported that it had restructured its outstanding convertible promissory note to extend the maturity

until December 2026, as well as entered into a non-convertible promissory note that was used to reduce the outstanding balance of the

convertible note. Additionally, the Company completed a public offering of common stock and accompanying warrants in March

2026, for approximately $4.0 million of net proceeds, after deducting placement agent fees and other offering expenses. In April 2026,

the Company completed a registered direct offering of common stock and, in a concurrent private placement, accompanying warrants, for

$4.2 million of net proceeds, after deducting placement agent fees and other offering expenses. As of March 31, 2026, Outlook Therapeutics

had cash and cash equivalents of $7.7 million, which does not include the net proceeds of the April 2026 registered direct offering.

About ONS-5010 / LYTENAVA™ (bevacizumab-vikg, bevacizumab

gamma)

ONS-5010/LYTENAVA™ is an ophthalmic formulation

of bevacizumab produced in the United States for the treatment of wet AMD. LYTENAVA™ (bevacizumab gamma) is the subject of a centralized

Marketing Authorization granted by the European Commission in the EU and a Marketing Authorization granted by the Medicines and Healthcare

products Regulatory Agency (MHRA) in the UK for the treatment of wet AMD.

In the United States, ONS-5010/LYTENAVA ™

(bevacizumab-vikg) is investigational. In certain European Union Member States, ONS-5010/LYTENAVA™ must receive pricing and reimbursement

approval before it can be sold.

Bevacizumab-vikg (bevacizumab gamma in the EU

and UK) is a recombinant humanized monoclonal antibody (mAb) that selectively binds with high affinity to all isoforms of human vascular

endothelial growth factor (VEGF) and neutralizes VEGF’s biologic activity through a steric blocking of the binding of VEGF to its

receptors Flt-1 (VEGFR-1) and KDR (VEGFR-2) on the surface of endothelial cells. Following intravitreal injection, the binding of bevacizumab

to VEGF prevents the interaction of VEGF with its receptors on the surface of endothelial cells, reducing endothelial cell proliferation,

vascular leakage, and new blood vessel formation in the retina.

About Outlook Therapeutics, Inc.

Outlook Therapeutics is a biopharmaceutical company

focused on the development and commercialization of ONS-5010/LYTENAVA™ (bevacizumab-vikg, bevacizumab gamma) to enhance the standard

of care for bevacizumab for the treatment of retinal diseases. LYTENAVA™ (bevacizumab gamma) is the first ophthalmic formulation

of bevacizumab to receive European Commission and MHRA Marketing Authorization for the treatment of wet AMD. Outlook Therapeutics commenced

commercial launch of LYTENAVA™ (bevacizumab gamma) in Germany and the UK as a treatment for wet AMD.

In the United States, ONS-5010/LYTENAVA™

(bevacizumab-vikg) is investigational. If approved in the United States, ONS-5010/LYTENAVA™ would be the first approved ophthalmic

formulation of bevacizumab for use in retinal indications, including wet AMD.

Non-GAAP Financial Measures

Outlook Therapeutics prepares its consolidated

financial statements in conformity with accounting principles generally accepted in the United States of America (U.S. GAAP) and pursuant

to accounting requirements of the Securities and Exchange Commission (SEC). In an effort to provide investors with additional information

regarding the results and to provide a meaningful period-over-period comparison of Outlook Therapeutics’ financial performance,

Outlook Therapeutics sometimes uses non-U.S. GAAP financial measures (NGFM) as defined by the SEC. In this press release, Outlook Therapeutics

uses “adjusted net loss attributable to common stockholders,” which is defined as net loss attributable to common stockholders

excluding warrant inducement expenses, gain on extinguishment of debt and changes in fair value of warrants and convertible promissory

notes, as well as “adjusted net loss attributable to common stockholders per share of common stock – basic and diluted,”

which is defined as net loss attributable to common stockholders per share of common stock – basic and diluted, excluding warrant

inducement expenses, gain on extinguishment of debt and changes in fair value of warrants and convertible promissory notes. Management

uses these NGFMs because they adjust for certain non-cash items that impact financial results but not cash flows, and that management

believes are not related to its core business. Management uses these NGFMs to evaluate Outlook Therapeutics’ financial performance

against internal budgets and targets. Management believes that these NGFMs are useful for evaluating Outlook Therapeutics’ core

operating results and facilitating comparison across reporting periods. Outlook Therapeutics believes these NGFMs should be considered

in addition to, and not in lieu of, GAAP financial measures. Outlook Therapeutics’ NGFMs may be different from the same NGFMs used

by other companies. Reconciliations to the closest U.S. GAAP financial measures are provided in the tables below.

Forward-Looking Statements

This press release contains statements that are, or may be deemed to be “forward-looking statements”. All statements other

than statements of historical facts are “forward-looking statements,” including those relating to future events. In some cases,

you can identify forward-looking statements by terminology such as “anticipate,” “are,” “believe,”

“can,” “continue,” “expect,” “may,” “on track,” “plan,” “potential,”

“target,” “will,” or “would” the negative of terms like these or other comparable terminology, and

other words or terms of similar meaning. These include, among others, expectations concerning Outlook Therapeutics’ ability to remediate

or otherwise resolve deficiencies identified in the CRL issued by the FDA, expectations concerning decisions of regulatory bodies and

the timing thereof, including market exclusivity, the potential to receive approval from the FDA and the timing thereof, statements about

Outlook Therapeutics’ commercialization strategy, including plans for commercial launch of LYTENAVA™ in additional markets

and the timing thereof and potential partnerships in those countries, expectations regarding receipt of Marketing Authorization for LYTENAVA™

in Switzerland, expectations concerning Outlook Therapeutics’ partnership with Mediconsult AG in Switzerland, the potential of ONS-5010/LYTENAVA™

as a treatment for wet AMD, the market opportunity for LYTENAVA™ in Europe and the United States, expectations concerning Outlook’s

financial performance and condition, and other statements that are not historical fact. Although Outlook Therapeutics believes that it

has a reasonable basis for the forward-looking statements contained herein, they are based on current expectations about future events

affecting Outlook Therapeutics and are subject to risks, uncertainties, and factors relating to its operations and business environment,

all of which are difficult to predict and many of which are beyond its control. These risk factors include those risks associated with

developing and commercializing pharmaceutical product candidates, risks of conducting clinical trials and risks in obtaining necessary

regulatory approvals, the content and timing of decisions by regulatory bodies, the sufficiency of Outlook Therapeutics’ resources,

as well as those risks detailed in Outlook Therapeutics’ filings with the Securities and Exchange Commission (the SEC), including

the Annual Report on Form 10-K for the fiscal year ended September 30, 2025, filed with the SEC on December 19, 2025, as supplemented

by future reports Outlook Therapeutics files with the SEC, which include uncertainty of market conditions and future impacts related to

macroeconomic factors, including as a result of global geopolitical conflict, tariffs and trade tensions, fluctuations in interest rates

and inflation and potential future bank failures on the global business environment. These risks may cause actual results to differ materially

from those expressed or implied by forward-looking statements in this press release. All forward-looking statements included in this press

release are expressly qualified in their entirety by the foregoing cautionary statements. You are cautioned not to place undue reliance

on these forward-looking statements, which speak only as of the date hereof. Outlook Therapeutics does not undertake any obligation to

update, amend or clarify these forward-looking statements whether as a result of new information, future events or otherwise, except as

may be required under applicable securities law.

Investor Inquiries:

Jenene Thomas

Chief Executive Officer

JTC Team, LLC

T: 908.824.0775

OTLK@jtcir.com

Outlook Therapeutics, Inc.

Consolidated Statements of Operations

(Amounts in thousands, except per share data)

Three months ended March 31,

Six months ended March 31,

2026

2025

2026

2025

Revenues, net

$ 128

$ —

$ (1,080 )

$ —

Cost of revenues

150

179

Gross profit

(22 )

(1,259 )

Operating expenses:

Research and development

$ 4,500

$ 4,407

8,135

14,067

Selling, general and administrative

9,505

7,984

18,117

19,931

Loss from operations

(14,027 )

(12,391 )

(27,511 )

(33,998 )

Loss on equity method investment

45

36

83

70

Interest expense (income)

19

(30 )

(Gain) loss from change in fair value of promissory notes

(2,495 )

2,111

4,249

3,415

Warrant inducement expenses

33,857

33,857

Gain from change in fair value of warrant liability

(6,838 )

(2,060 )

(4,046 )

(42,333 )

Gain on extinguishment of debt

(286 )

(286 )

Net loss before income tax

$ (4,453 )

$ (46,354 )

$ (27,511 )

$ (28,977 )

Income tax expense

3

3

Net loss

(4,453 )

(46,357 )

(27,511 )

(28,980 )

Per share information:

Net loss per share of common stock, basic and diluted

$ (0.05 )

$ (1.50 )

$ (0.39 )

$ (1.05 )

Weighted average shares outstanding, basic and diluted

81,836

30,874

70,902

27,518

Condensed Consolidated Balance Sheet Data

(Amounts in thousands)

March 31, 2026

September 30, 2025

Cash and cash equivalents

$ 7,748

$ 8,083

Total assets

$ 21,892

$ 18,584

Current liabilities

$ 38,884

$ 45,815

Total stockholders' deficit

$ (28,995 )

$ (32,188 )

Reconciliation Between Reported Net Loss (GAAP) and Adjusted Net Loss (Non-GAAP), in each case

Attributable to Common Stockholders

(Amounts in thousands, except per share data)

Three months ended March 31,

Six months ended December 31,

2026

2025

2026

2025

Net loss attributable to common stockholders, as reported (GAAP)

$ (4,453 )

$ (46,357 )

$ (27,511 )

$ (28,980 )

Adjustments for reconciled items:

(Gain) loss from change in fair value of promissory notes

(2,495 )

2,111

4,249

3,415

Warrant inducement expenses

33,857

33,857

Gain from change in fair value of warrant liability

(6,838 )

(2,060 )

(4,046 )

(42,333 )

Gain on extinguishment of debt

(286 )

(286 )

Adjusted net loss attributable to common stockholders (non-GAAP)

$ (14,072 )

$ (12,449 )

$ (27,594 )

$ (34,041 )

Net loss attributable to common stockholders per share of

common stock - basic as reported (GAAP)

$ (0.05 )

$ (1.50 )

$ (0.39 )

$ (1.05 )

Adjustments for reconciled items:

(Gain) loss from change in fair value of promissory notes

(0.03 )

0.07

0.06

0.12

Warrant inducement expenses

1.10

1.23

Gain from change in fair value of warrant liability

(0.08 )

(0.07 )

(0.06 )

(1.54 )

Gain on extinguishment of debt

-

-

-

-

Adjusted net loss attributable to common stockholders

per share of common stock - basic (non-GAAP)

$ (0.16 )

$ (0.40 )

$ (0.39 )

$ (1.24 )

Weighted average shares outstanding, basic

81,835,900

30,874,396

70,901,617

27,517,692

Weighted average shares - diluted

81,835,900

# 30,874,396

70,901,617

27,517,692

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Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 13e

-Subsection 4c

+ Details

Name:

dei_PreCommencementIssuerTenderOffer

Namespace Prefix:

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Data Type:

xbrli:booleanItemType

Balance Type:

na

Period Type:

duration

X

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 14d

-Subsection 2b

+ Details

Name:

dei_PreCommencementTenderOffer

Namespace Prefix:

dei_

Data Type:

xbrli:booleanItemType

Balance Type:

na

Period Type:

duration

X

- Definition

Title of a 12(b) registered security.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection b

+ Details

Name:

dei_Security12bTitle

Namespace Prefix:

dei_

Data Type:

dei:securityTitleItemType

Balance Type:

na

Period Type:

duration

X

- Definition

Name of the Exchange on which a security is registered.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 12

-Subsection d1-1

+ Details

Name:

dei_SecurityExchangeName

Namespace Prefix:

dei_

Data Type:

dei:edgarExchangeCodeItemType

Balance Type:

na

Period Type:

duration

X

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as soliciting material pursuant to Rule 14a-12 under the Exchange Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Exchange Act

-Number 240

-Section 14a

-Subsection 12

+ Details

Name:

dei_SolicitingMaterial

Namespace Prefix:

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Data Type:

xbrli:booleanItemType

Balance Type:

na

Period Type:

duration

X

- Definition

Trading symbol of an instrument as listed on an exchange.

+ References

No definition available.

+ Details

Name:

dei_TradingSymbol

Namespace Prefix:

dei_

Data Type:

dei:tradingSymbolItemType

Balance Type:

na

Period Type:

duration

X

- Definition

Boolean flag that is true when the Form 8-K filing is intended to satisfy the filing obligation of the registrant as written communications pursuant to Rule 425 under the Securities Act.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Securities Act

-Number 230

-Section 425

+ Details

Name:

dei_WrittenCommunications

Namespace Prefix:

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Data Type:

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Balance Type:

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Period Type:

duration