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Form 8-K

sec.gov

8-K — GT Biopharma, Inc.

Accession: 0001493152-26-042672

Filed: 2026-09-15

Period: 2026-09-14

CIK: 0000109657

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Entry into a Material Definitive Agreement

Item: Unregistered Sales of Equity Securities

Item: Material Modifications to Rights of Security Holders

Item: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

Item: Financial Statements and Exhibits

Documents

8-K — form8-k.htm (Primary)

EX-3.1 (ex3-1.htm)

EX-4.1 (ex4-1.htm)

EX-4.2 (ex4-2.htm)

EX-10.1 (ex10-1.htm)

EX-10.2 (ex10-2.htm)

EX-10.3 (ex10-3.htm)

EX-10.4 (ex10-4.htm)

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8-K

8-K (Primary)

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0000109657

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UNITED

STATES

SECURITIES

AND EXCHANGE COMMISSION

Washington,

D.C. 20549

FORM

8-K

CURRENT

REPORT

Pursuant

to Section 13 OR 15(d) of The Securities Exchange Act of 1934

Date

of Report:

(Date

of earliest event reported)

September

14, 2026

GT

Biopharma, Inc.

(Exact

name of registrant as specified in its charter)

Delaware

(State

or other Jurisdiction of Incorporation)

1-40023

94-1620407

(Commission

File Number)

(IRS Employer

Identification No.)

N/A1

(Address

of Principal Executive Offices and zip code)

(415)-919-4040

(Registrant’s

telephone number, including area code)

Check

the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of registrant under any

of the following provisions:

☐

Written

communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐

Soliciting

material pursuant to Rule 14a-12(b) under the Exchange Act (17 CFR 240.14a-12(b))

☐

Pre-commencement

communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐

Pre-commencement

communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities

registered pursuant to Section 12(b) of the Act:

Title

of each Series

Trading

Symbol(s)

Name

of each Exchange on which registered

Common

stock, $0.001 par value

GTBP

The

Nasdaq Stock Market LLC

Indicate

by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405

of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging

growth company ☐

If

an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying

with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

1Effective

as of July 1, 2024, the Company became a fully remote company. We do not maintain a principal executive office. For purposes of compliance

with applicable requirements of the Securities Act of 1933, as amended, and the Securities Exchange Act of 1934, as amended, any stockholder

communication required to be sent to the Company’s principal executive offices may be directed to 505 Montgomery Street, 10th Floor,

San Francisco, California 94111, or by email to auditcommittee@gtbiopharma.com.

Item

1.01 Entry into a Material Definitive Agreement.

Private

Placement of Preferred Stock and Warrants

On

September 14, 2026, GT Biopharma, Inc. (the “Company”) entered into a Securities Purchase Agreement (the “Securities

Purchase Agreement”) with the purchasers identified therein (collectively, the “Purchasers”) providing for the issuance

and sale to the Purchasers of (i) up to 8,277.778 shares of the Company’s Series M 10% Convertible Preferred Stock (the “Preferred

Stock”), (ii) warrants to purchase up to a number of shares of common stock of the Company (the “Common Stock”) equal

to 100% of the shares of the Company’s Common Stock issuable upon conversion of the shares of Preferred Stock (the “Common

Warrants”), and (iii) warrants to purchase up to a number of shares of the Company’s Common Stock equal to the number of

Greenshoe Conversion Shares (as defined in the Securities Purchase Agreement) issuable upon exercise of the Greenshoe Right (as defined

below) (the “Vesting Warrants” and together with the Common Warrants, the “Warrants”), with an aggregate stated

value of $8,277,778, for an aggregate purchase price of $7,450,000 (the “Offering”).

Pursuant

to the Securities Purchase Agreement, each Purchaser may elect to purchase shares of Preferred Stock with an aggregate stated value of

up to $33,333,333 (the “Greenshoe Rights”) for an aggregate purchase price of $30,000,000, subject to adjustments, as further

described in the Securities Purchase Agreement. Each Purchaser is entitled to exercise its respective Greenshoe Rights for an amount

of Preferred Stock equal to the ratio of such Purchaser’s original subscription amount to the original aggregate subscription amount

of all Purchasers.

Pursuant

to the Certificate of Designation of Preferences, Rights and Limitations of Series M 10% Convertible Preferred Stock (the “Certificate

of Designation”), and subject to certain ownership limitations, the Preferred Stock may be converted at any time at the option

of the Purchasers into shares of the Company’s Common Stock at an initial conversion price of $6.10, subject to certain conditions,

as further described in the Certificate of Designation. In addition, the holders of the Preferred Stock are entitled to receive cumulative

dividends at the rate per share (as a percentage of the stated value per share) of 10% per annum until September 13, 2027, increasing

to 12% per annum thereafter, payable quarterly on January 1, April 1, July 1 and October 1, beginning on the first such date after the

date of issuance of the Preferred Stock and on each Conversion Date (as defined in the Certificate of Designation), with respect only

to Preferred Stock being converted, in cash, shares of the Company’s Common Stock (subject to the Company’s satisfaction

of the conditions set forth in the Certificate of Designation), or a combination thereof.

Pursuant

to the Securities Purchase Agreement, each Purchaser will be issued (i) a Common Warrant, each to purchase up to a number of shares of

the Company’s Common Stock equal to 100% of the Conversion Shares underlying the Preferred Shares issued to such Purchaser and

(ii) a Vesting Warrant (the exercisability of which shall vest ratably from time to time in proportion to the Purchaser’s (or its

permitted assigns’) exercise of such Purchaser’s Greenshoe Rights pursuant to Section 2.4 of the Securities Purchase Agreement),

each to purchase up to a number of shares of the Company’s Common Stock equal to the number of Greenshoe Conversion Shares (as

defined in the Securities Purchase Agreement) applicable to such Purchaser, in accordance with the Securities Purchase Agreement. The

Common Warrants have an initial exercise price of $6.10 per share, are exercisable, subject to certain ownership limitations, immediately

upon issuance and have a term of exercise equal to five years. The Vesting Warrants have an initial exercise price of $6.10 per share,

are exercisable, subject to certain vesting and ownership limitations, and have a term of exercise equal to five years from the date

that the applicable warrant shares vest.

The

Preferred Shares and Warrants both have full ratchet price protection and are subject to other adjustments (including for reverse and

forward splits, recapitalizations and similar transactions), as further described in the Certificate of Designation or the Warrants,

as applicable. With respect to adjustments in connection with the exercise of Greenshoe Rights, in the first instance, there will not

be a floor price; provided, however, if the Company receives written notice from The Nasdaq Stock Market that a floor price should be

implemented, a floor price of $1.282 shall be set.

The

securities in the Offering were offered privately pursuant to Rule 506(b) of Regulation D under the Securities Act of 1933, as amended.

Registration

Rights Agreement

The

Company and the Purchasers entered into a registration rights agreement (the “Registration Rights Agreement”) pursuant to

which the Company agreed to file a registration statement with the Securities and Exchange Commission (the “SEC”) covering

the public resale of the shares of Common Stock issuable upon conversion of the Preferred Stock and upon exercise of the Warrants. The

Company has agreed to file a registration statement within thirty (30) days after the initial closing and after each closing of the exercise

of a Greenshoe Right in accordance with the Securities Purchase Agreement, to become effective no later than sixty (60) days after the

Closing Date (as defined in the Securities Purchase Agreement) or each Trigger Date (as defined in the Registration Rights Agreement),

or in the event of a “full review” by the SEC, ninety (90) days after the Closing Date or each Trigger Date. If these deadlines

are not met, the Company will be liable for partial liquidated damages of 1.5% of the subscription amount paid by each Purchaser pursuant

to the Securities Purchase Agreement. Further, if the Company fails to pay such liquidated damages within seven days from the date payable,

the Company will pay interest thereon at the prime rate plus 12% to each holder of the registerable securities.

Voting

Agreement

Pursuant

to the Securities Purchase Agreement, the Company agreed to hold a meeting of its stockholders at the earliest practical date after the

execution of the Securities Purchase Agreement for the purpose of (i) obtaining shareholder approval for the issuance, in the aggregate,

of more than 19.99% of the number of shares of the Company’s Common Stock outstanding on the date of the initial closing (“Shareholder

Approval”) and (ii) obtaining such shareholder approval as may be required to effect any necessary increase in authorized shares

of Common Stock if the number of Underlying Shares (as defined the Securities Purchase Agreement) is greater than the number of authorized

shares of Common Stock. In connection with the required Shareholder Approval, all of the Company’s officers and directors (each

a “Voting Agreement Party”) entered into a voting agreement (the “Voting Agreement”) pursuant to which each Voting

Agreement Party agreed to vote all shares of voting stock over which the Voting Agreement Party has voting control in favor of any proposal

presented to the stockholders of the Company seeking the Shareholder Approval.

Lock-Up

Agreement

Pursuant

to the Securities Purchase Agreement, the Company and its directors and officers entered into lockup agreements (the “Lockup Agreements”),

pursuant to which each officer and director agreed not to sell or transfer any securities of the Company held by them for a period commencing

on the date of the Lockup Agreement until thirty (30) days after the later of (i) the Effective Date (as defined in the Securities Purchase

Agreement) and (ii) the date that Shareholder Approval is obtained and deemed effective, subject to limited exceptions.

The

foregoing descriptions of the terms of the Certificate of Designation, form of Common Warrant, form of Vesting Warrant, Securities Purchase

Agreement, Registration Rights Agreement, Voting Agreement and Lockup Agreement are not intended to be complete and are qualified in

their entirety by reference to such exhibits, which are filed herewith as Exhibits 3.1, 4.1, 4.2, 10.1, 10.2, 10.3 and 10.4, respectively,

to this Current Report on Form 8-K and are incorporated by reference herein. Neither this current report on Form 8-K, nor the exhibits

attached hereto, is an offer to sell or the solicitation of an offer to buy the securities described herein.

Item

3.02 Unregistered Sales of Equity Securities.

The

information set forth in Item 1.01 is incorporated by reference into this Item 3.02 in its entirety.

Item

3.03 Material Modification to Rights of Security Holders.

The

information set forth in Item 1.01 is incorporated by reference into this Item 3.03 in its entirety.

On

September 14, 2026, the Company filed the Certificate of Designation with the Secretary of State of the State of Delaware, in the form

attached as Exhibit 3.1 to this Current Report on Form 8-K. The Certificate of Designation creates and specifies the rights of Series

M 10% Convertible Preferred Stock, including the terms and conditions on which shares of such preferred stock would convert into shares

of our Common Stock, as well as its liquidation preference.

Item

5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.

The

information set forth in Items 1.01 and 3.03 regarding the Certificate of Designation are incorporated by reference into this Item 5.03

in its entirety.

Item

9.01 Financial Statements and Exhibits.

(d)

Exhibits

Exhibit

No.

Description

3.1

Certificate of Designation of Preferences, Rights and Limitations of Series M 10% Convertible Preferred Stock.

4.1

Form of Common Warrant.

4.2

Form of Vesting Warrant.

10.1

Securities Purchase Agreement, dated as of September 14, 2026, between the Company and the purchasers identified therein.

10.2

Registration Rights Agreement, dated as of September 14, 2026, between the Company and the purchasers identified therein.

10.3

Form of Voting Agreement.

10.4

Form of Lock-up Agreement.

104

Cover

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SIGNATURES

Pursuant

to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by

the undersigned hereunto duly authorized.

GT

BIOPHARMA, INC.

Date:

September 15, 2026

By:

/s/

Alan Urban

Alan

Urban

Chief

Financial Officer

EX-3.1

EX-3.1

Filename: ex3-1.htm · Sequence: 2

Exhibit

3.1

gt

biopharma, Inc.

CERTIFICATE

OF DESIGNATION OF PREFERENCES,

RIGHTS

AND LIMITATIONS

OF

Series

M 10% CONVERTIBLE PREFERRED STOCK

PURSUANT

TO SECTION 151 OF THE

Delaware

GENERAL CORPORATION LAW

The

undersigned, Michael Breen and Alan Urban, do hereby certify that:

1.

They are the Chief Executive Officer and Secretary, respectively, of GT Biopharma, Inc., a Delaware corporation (the “Corporation”).

2.

The Corporation is authorized to issue 1,500,000 shares of preferred stock from time to time in one or more series.

3.

The following resolutions were duly adopted by the board of directors of the Corporation (the “Board of Directors”):

WHEREAS,

the certificate of incorporation of the Corporation provides for a class of its authorized stock known as preferred stock, consisting

of 1,500,000 shares, $0.01 par value per share, issuable from time to time in one or more series;

WHEREAS,

the Board of Directors is authorized to fix the dividend rights, dividend rate, voting rights, conversion rights, rights and terms of

redemption and liquidation preferences of any wholly unissued series of preferred stock and the number of shares constituting any series

and the designation thereof, of any of them; and

WHEREAS,

it is the desire of the Board of Directors, pursuant to its authority as aforesaid, to fix the rights, preferences, restrictions and

other matters relating to a series of the preferred stock, which shall consist of, except as otherwise set forth in the Purchase Agreement,

up to 41,778 shares of the preferred stock which the Corporation has the authority to issue, as follows:

NOW,

THEREFORE, BE IT RESOLVED, that the Board of Directors does hereby provide for the issuance of a series of preferred stock for cash or

exchange of other securities, rights or property and does hereby fix and determine the rights, preferences, restrictions and other matters

relating to such series of preferred stock as follows:

1

TERMS

OF PREFERRED STOCK

Section

1. Definitions. For the purposes hereof, the following terms shall have the following meanings:

“Affiliate”

means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control

with a Person, as such terms are used in and construed under Rule 405 of the Securities Act.

“Alternate

Consideration” shall have the meaning set forth in Section 7(e).

“Bankruptcy

Event” means any of the following events: (a) the Corporation or any Significant Subsidiary (as such term is defined in Rule

1-02(w) of Regulation S-X) thereof commences a case or other proceeding under any bankruptcy, reorganization, arrangement, adjustment

of debt, relief of debtors, dissolution, insolvency or liquidation or similar law of any jurisdiction relating to the Corporation or

any Significant Subsidiary thereof, (b) there is commenced against the Corporation or any Significant Subsidiary thereof any such case

or proceeding that is not dismissed within 60 days after commencement, (c) the Corporation or any Significant Subsidiary thereof is adjudicated

insolvent or bankrupt or any order of relief or other order approving any such case or proceeding is entered, (d) the Corporation or

any Significant Subsidiary thereof suffers any appointment of any custodian or the like for it or any substantial part of its property

that is not discharged or stayed within 60 calendar days after such appointment, (e) the Corporation or any Significant Subsidiary thereof

makes a general assignment for the benefit of creditors, (f) the Corporation or any Significant Subsidiary thereof calls a meeting of

its creditors with a view to arranging a composition, adjustment or restructuring of its debts, or (g) the Corporation or any Significant

Subsidiary thereof, by any act or failure to act, expressly indicates its consent to, approval of or acquiescence in any of the foregoing

or takes any corporate or other action for the purpose of effecting any of the foregoing.

“Base

Conversion Price” shall have the meaning set forth in Section 7(b).

“Beneficial

Ownership Limitation” shall have the meaning set forth in Section 6(d).

“Business

Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the United States or any day

on which banking institutions in the State of New York are authorized or required by law or other governmental action to close.

“Buy-In”

shall have the meaning set forth in Section 6(c)(iv).

“Closing”

means the closing of the purchase and sale of the Securities pursuant to Section 2.1 of the Purchase Agreement.

2

“Closing

Date” means the Trading Day on which all of the Transaction Documents have been executed and delivered by the applicable parties

thereto and all conditions precedent to (i) each Holder’s obligations to pay the Subscription Amount and (ii) the Corporation’s

obligations to deliver the Securities have been satisfied or waived.

“Closing

Price” means on any particular date (a) the last reported closing bid price per share of Common Stock on such date on

the Trading Market (as reported by Bloomberg L.P. at 4:15 p.m. (New York City time)), (b) if there is no such price on such date, then

the closing bid price on the Trading Market on the date nearest preceding such date (as reported by Bloomberg L.P. at 4:15 p.m. (New

York City time)), (c)  if the Common Stock is not then listed or quoted on another Trading Market and if prices for the Common Stock

are then reported on the Pink Market, the most recent bid price per share of the Common Stock so reported, or (d) if the shares

of Common Stock are not then publicly traded the fair market value as of such date of a share of Common Stock as determined by an independent

appraiser selected in good faith by the Corporation and reasonably acceptable to the Holders of a majority in interest of the shares

then outstanding, the fees and expenses of which shall be paid by the Corporation.

“Commission”

means the United States Securities and Exchange Commission.

“Common

Stock” means the Corporation’s common stock, par value $0.001 per share, and stock of any other class of securities into

which such securities may hereafter be reclassified or changed.

“Common

Stock Equivalents” means any securities of the Corporation or the Subsidiaries which would entitle the holder thereof to acquire

at any time Common Stock, including, without limitation, any debt, preferred stock, rights, options, warrants or other instrument that

is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock.

“Conversion

Amount” means the sum of the Stated Value at issue.

“Conversion

Date” shall have the meaning set forth in Section 6(a).

“Conversion

Price” shall have the meaning set forth in Section 6(b).

“Conversion

Shares” means, collectively, the shares of Common Stock issuable upon conversion of the shares of Preferred Stock in accordance

with the terms hereof.

“Conversion

Shares Registration Statement” means a registration statement that registers the resale of all or any portion of the Conversion

Shares by the Holders, which shall be named as “selling stockholders” therein, and meets the requirements of the Registration

Rights Agreement.

“Dilutive

Issuance” shall have the meaning set forth in Section 7(b).

3

“Dilutive

Issuance Notice” shall have the meaning set forth in Section 7(b).

“Dividend

Conversion Rate” means the lesser of (a) the Conversion Price or (b) 90% of the lesser of (i) the average of the VWAPs for

the 5 consecutive Trading Days ending on the Trading Day that is immediately prior to the applicable Dividend Payment Date or (ii) the

average of the VWAPs for the 5 consecutive Trading Days ending on the Trading Day that is immediately prior to the date the applicable

Dividend Conversion Shares are issued and delivered if such delivery is after the Dividend Payment Date.

“Dividend

Conversion Shares” shall have the meaning set forth in Section 3(a).

“Dividend

Notice Period” shall have the meaning set forth in Section 3(a).

“Dividend

Payment Date” shall have the meaning set forth in Section 3(a).

“Dividend

Share Amount” shall have the meaning set forth in Section 3(a).

“Effective

Date” means the date that the initial Conversion Shares Registration Statement filed by the Corporation pursuant to the Registration

Rights Agreement is first declared effective by the Commission.

“Equity

Conditions” means, during the period in question, (a) the Corporation shall have duly honored all conversions scheduled to

occur or occurring by virtue of one or more Notices of Conversion of the applicable Holder on or prior to the dates so requested or required,

if any, (b) the Corporation shall have paid all liquidated damages and other amounts owing to the applicable Holder in respect of the

Preferred Stock, (c)(i) there is an effective Conversion Shares Registration Statement pursuant to which the Holders are permitted to

utilize the prospectus thereunder to resell the shares of Common Stock in question registered for resale thereunder (and the Corporation

believes, in good faith, that such effectiveness will continue uninterrupted for the foreseeable future) or (ii) all of the Conversion

Shares issuable pursuant to the Transaction Documents (and shares issuable in lieu of cash payments of dividends) may be resold pursuant

to Rule 144 without volume or manner-of-sale restrictions or current public information requirements as determined by the counsel to

the Corporation as set forth in a written opinion letter to such effect, addressed and acceptable to the Transfer Agent and the affected

Holders, (d) the Common Stock is trading on a Trading Market and all of the shares issuable pursuant to the Transaction Documents are

listed or quoted for trading on such Trading Market (and the Corporation believes, in good faith, that trading of the Common Stock on

a Trading Market will continue uninterrupted for the foreseeable future), (e) there is a sufficient number of authorized, but unissued

and otherwise unreserved, shares of Common Stock for the issuance of all of the shares then issuable pursuant to the Transaction Documents,

(f) the issuance of the shares in question to the applicable Holder would not violate the limitations set forth in Section 6(d), (g)

the Corporation shall have obtained Shareholder Approval and the restrictions set forth in Section 6(e) shall no longer apply, (h) there

has been no public announcement of a pending or proposed Fundamental Transaction that has not been consummated, (i) the applicable Holder

is not in possession of any information provided by the Corporation, any of its Subsidiaries, or any of their officers, directors, employees,

agents or Affiliates, that constitutes, or may constitute, material non-public information and (j) for each Trading Day in a period of

20 consecutive Trading Days prior to the applicable date in question, the daily trading volume for the Common Stock on the principal

Trading Market exceeds $100,000 per Trading Day.

4

“Exchange

Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder.

“Exempt

Issuance” means the issuance of (a) shares of Common Stock or options to employees, officers or directors of the Corporation

pursuant to any stock or option plan duly adopted by a majority of the non-employee members of the Board of Directors of the Corporation

or a majority of the members of a committee of non-employee directors established for such purpose, (b) securities upon the exercise

or exchange of or conversion of any securities issued pursuant to the Purchase Agreement (including the Vesting Warrants (as defined

in Section 1.1 of the Purchase Agreement)) and/or other securities exercisable or exchangeable for or convertible into shares of Common

Stock issued and outstanding on the date of the Purchase Agreement, provided that such securities have not been amended since the date

of the Purchase Agreement to increase the number of such securities or to decrease the exercise price, exchange price or conversion price

of any such securities (other than in connection with stock splits or combinations and other than pursuant to Section 3(b) of the Vesting

Warrants) or to extend the term of such securities or (c) securities issued pursuant to acquisitions or strategic transactions approved

by a majority of the disinterested directors of the Corporation, provided that such securities are issued as “restricted securities”

(as defined in Rule 144) and carry no registration rights that require or permit the filing of any registration statement in connection

therewith during the prohibition period in Section 4.13(a) of the Purchase Agreement, and provided that any such issuance shall only

be to a Person (or to the equityholders of a Person) which is, itself or through its subsidiaries, an operating company or an owner of

an asset in a business synergistic with the business of the Corporation and shall provide to the Corporation additional benefits in addition

to the investment of funds, but shall not include a transaction in which the Corporation is issuing securities primarily for the purpose

of raising capital or to an entity whose primary business is investing in securities. Notwithstanding anything herein to the contrary,

in no event shall the exercise of the Greenshoe Rights pursuant to Section 2.4 of the Purchase Agreement be deemed an Exempt Issuance

hereunder.

“Fundamental

Transaction” shall have the meaning set forth in Section 7(e).

“GAAP”

means United States generally accepted accounting principles.

“Holder”

shall have the meaning given such term in Section 2.

5

“Indebtedness”

means (a) any liabilities for borrowed money or amounts owed in excess of $50,000 (other than trade accounts payable incurred in the

ordinary course of business), (b) all guaranties, endorsements and other contingent obligations in respect of indebtedness of others,

whether or not the same are or should be reflected in the Corporation’s balance sheet (or the notes thereto), except guaranties

by endorsement of negotiable instruments for deposit or collection or similar transactions in the ordinary course of business, and (c)

the present value of any lease payments in excess of $50,000 due under leases required to be capitalized in accordance with GAAP.

“Issuable

Maximum” shall have the meaning set forth in Section 6(e).

“Junior

Securities” means the Common Stock and all other Common Stock Equivalents of the Corporation other than those securities which

are explicitly senior or pari passu to the Preferred Stock in dividend rights or liquidation preference.

“Liens”

means a lien, charge, security interest, encumbrance, right of first refusal, preemptive right or other restriction.

“Liquidation”

shall have the meaning set forth in Section 5.

“New

York Courts” shall have the meaning set forth in Section 9(d).

“Notice

of Conversion” shall have the meaning set forth in Section 6(a).

“Original

Issue Date” means the date of the first issuance of any shares of the Preferred Stock regardless of the number of transfers

of any particular shares of Preferred Stock and regardless of the number of certificates which may be issued to evidence such Preferred

Stock.

“Permitted

Indebtedness” means (a) the Indebtedness existing on the Original Issue Date and (b) lease obligations and purchase money indebtedness

incurred in connection with the acquisition of capital assets and lease obligations with respect to newly acquired or leased assets.

“Permitted

Lien” means the individual and collective reference to the following: (a) Liens for taxes, assessments and other governmental

charges or levies not yet due or Liens for taxes, assessments and other governmental charges or levies being contested in good faith

and by appropriate proceedings for which adequate reserves (in the good faith judgment of the management of the Corporation) have been

established in accordance with GAAP, (b) Liens imposed by law which were incurred in the ordinary course of the Corporation’s business,

such as carriers’, warehousemen’s and mechanics’ Liens, statutory landlords’ Liens, and other similar Liens arising

in the ordinary course of the Corporation’s business, and which (x) do not individually or in the aggregate materially detract

from the value of such property or assets or materially impair the use thereof in the operation of the business of the Corporation and

its consolidated Subsidiaries or (y) are being contested in good faith by appropriate proceedings, which proceedings have the effect

of preventing for the foreseeable future the forfeiture or sale of the property or asset subject to such Lien, (c) Liens incurred in

connection with Permitted Indebtedness under clause (a) thereunder, and (d) Liens incurred in connection with Permitted Indebtedness

under clause (b) thereunder, provided that such Liens are not secured by assets of the Corporation or its Subsidiaries other than the

assets so acquired or leased.

6

“Person”

means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability

company, joint stock company, government (or an agency or subdivision thereof) or other entity of any kind.

“Preferred

Stock” shall have the meaning set forth in Section 2.

“Purchase

Agreement” means the Securities Purchase Agreement, dated as of the Original Issue Date, among the Corporation and the original

Holders, as amended, modified or supplemented from time to time in accordance with its terms.

“Registration

Rights Agreement” means the Registration Rights Agreement, dated as of the date of the Purchase Agreement, among the Corporation

and the original Holders, in the form of Exhibit B attached to the Purchase Agreement.

“Registration

Statement” means a registration statement meeting the requirements set forth in the Registration Rights Agreement and covering

the resale of the Underlying Shares by each Holder as provided for in the Registration Rights Agreement.

“Rule

144” means Rule 144 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended from time to

time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same effect as such Rule.

“Rule

424” means Rule 424 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted

from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose and effect

as such Rule.

“Securities”

means the Preferred Stock, the Warrants, the Warrant Shares and the Underlying Shares.

“Securities

Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.

“Share

Delivery Date” shall have the meaning set forth in Section 6(c).

“Stated

Value” shall have the meaning set forth in Section 2, as the same may be increased pursuant to Section 3.

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“Shareholder

Approval” means such approval as may be required by the applicable rules and regulations of the Nasdaq Stock Market (or any

successor entity) from the shareholders of the Corporation with respect to the transactions contemplated by the Transaction Documents,

including the issuance of all of the Underlying Shares in excess of 19.99% of the issued and outstanding Common Stock on the Closing

Date.

“Subscription

Amount” shall mean, as to each Holder, the aggregate amount to be paid for the Preferred Stock purchased pursuant to the Purchase

Agreement as specified below such Holder’s name on the signature page of the Purchase Agreement and next to the heading “Subscription

Amount,” in United States dollars and in immediately available funds.

“Subsidiary”

means any subsidiary of the Corporation as set forth on Schedule 3.1(a) of the Purchase Agreement and shall, where applicable,

also include any direct or indirect subsidiary of the Corporation formed or acquired after the date of the Purchase Agreement.

“Successor

Entity” shall have the meaning set forth in Section 7(e).

“Trading

Day” means a day on which the principal Trading Market is open for business.

“Trading

Market” means any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date

in question: the NYSE American, the Nasdaq Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market, the New York Stock

Exchange, the Pink Open Market operated by OTC Markets Group, Inc. (“Pink Market”), the OTCQB Venture Market (“OTCQB”)

or the OTCQX Best Market (“OTCQX”), or any successors to any of the foregoing.

“Trading

Price” means on any particular date (a) the lowest reported trading price per share of Common Stock on such date on the

Trading Market (as reported by Bloomberg L.P. at 4:15 p.m. (New York City time)), (b) if there is no such price on such date, then the

lowest trading price on the Trading Market on the date nearest preceding such date (as reported by Bloomberg L.P. at 4:15 p.m. (New York

City time)), (c)  if the Common Stock is not then listed or quoted on a Trading Market and if prices for the Common Stock are then

reported on The Pink Open Market (or a similar organization or agency succeeding to its functions of reporting prices), the lowest trading

price per share of the Common Stock so reported, or (d) if the shares of Common Stock are not then publicly traded the fair market

value as of such date of a share of Common Stock as determined by an independent appraiser selected in good faith by the Corporation

and reasonably acceptable to the Holders of a majority in interest of the shares then outstanding, the fees and expenses of which shall

be paid by the Corporation.

8

“Transaction

Documents” means this Certificate of Designation, the Purchase Agreement, the Warrants, the Registration Rights Agreement,

the Lock-Up Agreements, the Voting Agreement, all exhibits and schedules thereto and hereto and any other documents or agreements executed

in connection with the transactions contemplated pursuant to the Purchase Agreement.

“Underlying

Shares” means the shares of Common Stock issued and issuable upon conversion of the Preferred Stock, upon exercise of the Warrants

and issued and issuable in lieu of the cash payment of dividends on the Preferred Stock in accordance with the terms of this Certificate

of Designation.

“Variable

Rate Transaction” shall have the meaning ascribed to such term in Section 4.13(b) of the Purchase Agreement.

“VWAP”

means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed

or quoted on a Trading Market other than the Pink Market, the OTCQB or the OTCQX, the daily volume weighted average price of the Common

Stock for such date (or the nearest preceding date) on the Trading Market on which the Common Stock is then listed or quoted as reported

by Bloomberg L.P. (based on a Trading Day from 9:30 a.m. (New York City time) to 4:02 p.m. (New York City time)), (b)  if the Common

Stock is then listed or quoted on the OTCQB or the OTCQX, the volume weighted average price of the Common Stock for such date (or the

nearest preceding date) on the OTCQB or the OTCQX as applicable, (c) if the Common Stock is not then listed or quoted for trading on

the OTCQB or the OTCQX and if prices for the Common Stock are then reported in the Pink Market, the most recent bid price per share of

the Common Stock so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent

appraiser selected in good faith by the Purchasers of a majority in interest of the Securities then outstanding and reasonably acceptable

to the Corporation, the fees and expenses of which shall be paid by the Corporation.

“Warrants”

shall have the meaning ascribed to such term in Section 1.1 of the Purchase Agreement.

“Warrant

Shares” means the shares of Common Stock issuable upon exercise of the Warrants.

Section

2. Designation, Amount and Par Value; Ranking. The series of preferred stock shall be designated as its Series M 10% Convertible

Preferred Stock (the “Preferred Stock”) and the number of shares so designated shall be 41,778 (which shall not be

subject to increase without the written consent of the holders of a majority of the then outstanding shares of the Preferred Stock (each,

a “Holder” and collectively, the “Holders”)). Each share of Preferred Stock shall have a par value

of $0.001 per share and a stated value equal to $1,000, subject to increase set forth in Section 3 below (the “Stated Value”).

9

Except

to the extent that holders of at least 75% of the aggregate Stated Value of the then outstanding shares of Preferred Stock (the “Required

Holders”) expressly consent to the creation of additional Parity Stock or Senior Preferred Stock, all shares of capital stock

of the Corporation shall be junior in rank to all Preferred Stock with respect to the preferences as to dividends, distributions and

payments upon the liquidation, dissolution and winding up of the Corporation (such junior stock is referred to herein collectively as

“Junior Stock”). The rights of all such shares of capital stock of the Corporation shall be subject to the rights, powers,

preferences and privileges of the Preferred Stock. Without limiting any other provision of this Certificate of Designations, without

the prior express consent of the Required Holders, voting separately as a single class, the Corporation shall not hereafter authorize

or issue any additional or other shares of capital stock that are (i) of senior rank to the Preferred Stock in respect of the preferences

as to dividends, distributions and payments upon the liquidation, dissolution and winding up of the Corporation (collectively, the “Senior

Preferred Stock”), (ii) of pari passu rank to the Preferred Stock in respect of the preferences as to dividends, distributions

and payments upon the liquidation, dissolution and winding up of the Corporation (collectively, the “Parity Stock”);

provided, that the Corporation’s outstanding Series L 10% Convertible Preferred Stock shall rank pari passu with the Preferred

Stock and shall constitute Parity Stock, or (iii) any Junior Stock having a maturity date or any other date requiring redemption or repayment

of such shares of Junior Stock that is prior to the Maturity Date. In the event of the merger or consolidation of the Corporation with

or into another corporation, the Preferred Stock shall maintain their relative rights, powers, designations, privileges and preferences

provided for herein and no such merger or consolidation shall be consummated if it would result in the Preferred Stock being treated

in any manner inconsistently with the foregoing.

Section

3. Dividends.

a)

Dividends in Cash or in Kind. From and after the first date of issuance of any Preferred Stock, Holders shall be entitled to receive,

and the Corporation shall pay, cumulative dividends at the rate per share (as a percentage of the Stated Value per share) of 10% per

annum until September 13, 2027 and 12% per annum thereafter, payable quarterly on January 1, April 1, July 1 and October 1, beginning

on the first such date after the Original Issue Date and on each Conversion Date (with respect only to Preferred Stock being converted)

(each such date, a “Dividend Payment Date”) (if any Dividend Payment Date is not a Trading Day, the applicable payment

shall be due on the next succeeding Trading Day) in cash, or as set forth in this Section 3(a), in duly authorized, validly issued, fully

paid and non-assessable shares of Common Stock, or a combination thereof (the dollar amount to be paid in shares of Common Stock, the

“Dividend Share Amount”). The form of dividend payments to each Holder shall be determined in the following order

of priority: (i) if funds are legally available for the payment of dividends and the Equity Conditions have not been met during the 10

consecutive Trading Days immediately prior to the applicable Dividend Payment Date (the “Dividend Notice Period”),

in cash only, (ii) if funds are legally available for the payment of dividends and the Equity Conditions have been met during the Dividend

Notice Period, at the sole election of the Corporation, in cash or shares of Common Stock which shall be valued at the Dividend Conversion

Rate, (iii) if funds are not legally available for the payment of dividends and the Equity Conditions have been met during the Dividend

Notice Period, in shares of Common Stock which shall be valued at the Dividend Conversion Rate, (iv) if funds are not legally available

for the payment of dividends and the Equity Condition relating to an effective Conversion Shares Registration Statement has been waived

by such Holder (provided that the other Equity Conditions have been met during the Dividend Notice Period), as to such Holder only, in

unregistered shares of Common Stock which shall be valued at the Dividend Conversion Rate, and (v) if funds are not legally available

for the payment of dividends and the Equity Conditions have not been met during the Dividend Notice Period, then, at the election of

such Holder, such dividends shall accrue to the next Dividend Payment Date or shall be accreted to, and increase, the outstanding Stated

Value. In addition, as a condition to paying dividends in shares of Common Stock, as to such Dividend Payment Date, prior to such Dividend

Notice Period (but not more than five (5) Trading Days prior to the commencement of such Dividend Notice Period), the Corporation shall

have delivered to each Holder’s account with The Depository Trust Company a number of shares of Common Stock to be applied against

such Dividend Share Amount equal to the quotient of (x) the applicable Dividend Share Amount divided by (y) the Dividend Conversion Rate,

assuming for such purposes that the Dividend Payment Date is the Trading Day immediately prior to the commencement of the Dividend Notice

Period (the “Dividend Conversion Shares”); provided that on the Dividend Payment Date the Corporation shall issue

to the Holder any additional Dividend Conversion Shares owing to the Holder as a result of a lower Dividend Conversion Price during the

applicable Dividend Notice Period. The Holders shall have the same rights and remedies with respect to the delivery of any such shares

as if such shares were being issued pursuant to Section 6.

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b)

Corporation’s Ability to Pay Dividends in Cash or Kind. On the Closing Date, the Corporation shall have notified the Holders

whether or not it may legally pay cash dividends as of the Closing Date. The Corporation shall promptly notify the Holders at any time

the Corporation shall become able or unable, as the case may be, to legally pay cash dividends. If at any time the Corporation has the

right to pay dividends in cash or shares of Common Stock, the Corporation must provide the Holders with at least 10 Trading Days’

notice of its election to pay a regularly scheduled dividend in shares of Common Stock (the Corporation may indicate in such notice that

the election contained in such notice shall continue for later periods until revised by a subsequent notice). If at any time the Corporation

delivers a notice to the Holders of its election to pay the dividends in shares of Common Stock, the Corporation shall timely file a

prospectus supplement pursuant to Rule 424 disclosing such election. The aggregate number of shares of Common Stock otherwise issuable

to a Holder on a Dividend Payment Date shall be reduced by the number of shares of Common Stock previously issued to such Holder in connection

with such Dividend Payment Date. If any Dividend Conversion Shares are issued to a Holder in connection with a Dividend Payment Date

and are not applied against a Dividend Share Amount, then such Holder shall promptly return such excess shares to the Corporation.

c) Dividend

Calculations. Dividends on the Preferred Stock shall be calculated on the basis of a 360-day year, consisting of twelve 30

calendar day periods, and shall accrue daily commencing on the Original Issue Date, and shall be deemed to accrue from such date

whether or not earned or declared and whether or not there are profits, surplus or other funds of the Corporation legally available

for the payment of dividends. Payment of dividends in shares of Common Stock shall otherwise occur pursuant to Section 6(c)(i)

herein and, solely for purposes of the payment of dividends in shares, the Dividend Payment Date shall be deemed the Conversion

Date. Dividends shall cease to accrue with respect to any Preferred Stock converted, provided that, the Corporation actually

delivers the Conversion Shares within the time period required by Section 6(c)(i) herein. Except as otherwise provided herein, if at

any time the Corporation pays dividends partially in cash and partially in shares, then such payment shall be distributed ratably

among the Holders based upon the number of shares of Preferred Stock held by each Holder on such Dividend Payment Date.

d)

Late Fees. Any dividends, whether paid in cash or shares of Common Stock, that are not paid within three Trading Days following

a Dividend Payment Date shall continue to accrue and shall entail a late fee, which must be paid in cash, at the rate of 18% per annum

or the lesser rate permitted by applicable law which shall accrue daily from the Dividend Payment Date through and including the date

of actual payment in full.

e) Other

Securities. So long as any Preferred Stock shall remain outstanding, neither the Corporation nor any Subsidiary thereof shall

redeem, purchase or otherwise acquire directly or indirectly any Junior Securities. So long as any Preferred Stock shall remain

outstanding, neither the Corporation nor any Subsidiary thereof shall directly or indirectly pay or declare any dividend or make any

distribution upon (other than a dividend or distribution described in Section 6 or dividends due and paid in the ordinary course on

preferred stock of the Corporation at such times when the Corporation is in compliance with its payment and other obligations

hereunder), nor shall any distribution be made in respect of, any Junior Securities as long as any dividends due on the Preferred

Stock remain unpaid, nor shall any monies be set aside for or applied to the purchase or redemption (through a sinking fund or

otherwise) of any Junior Securities or shares pari passu with the Preferred Stock.

Section

4. Voting Rights. Except as otherwise provided herein or as otherwise required by law, the Preferred Stock shall have

no voting rights. However, as long as any shares of Preferred Stock are outstanding, the Corporation shall not, without the affirmative

vote of the Holders of a majority of the then outstanding shares of the Preferred Stock, (a) alter or change adversely the powers, preferences

or rights given to the Preferred Stock or alter or amend this Certificate of Designation, (b) authorize or create any class of stock

ranking as to dividends, redemption or distribution of assets upon a Liquidation (as defined in Section 5) senior to, or otherwise pari

passu with, the Preferred Stock, (c) amend its certificate of incorporation or other charter documents in any manner that adversely

affects any rights of the Holders, (d) increase the number of authorized shares of Preferred Stock, or (e) enter into any agreement with

respect to any of the foregoing.

11

Section

5. Liquidation. Upon any liquidation, dissolution or winding-up of the Corporation, whether voluntary or involuntary (a

“Liquidation”), the Holders shall be entitled to receive out of the assets, whether capital or surplus, of the

Corporation an amount equal to the Stated Value, plus any accrued and unpaid dividends thereon and any other fees or liquidated

damages then due and owing thereon under this Certificate of Designation, for each share of Preferred Stock before any distribution

or payment shall be made to the holders of any Junior Securities, and if the assets of the Corporation shall be insufficient to pay

in full such amounts, then the entire assets to be distributed to the Holders shall be ratably distributed among the Holders in

accordance with the respective amounts that would be payable on such shares if all amounts payable thereon were paid in full. A

Fundamental Transaction shall not be deemed a Liquidation. The Corporation shall mail written notice of any such Liquidation, not

less than 45 days prior to the payment date stated therein, to each Holder.

Section

6. Conversion.

a) Conversions

at Option of Holder. Each share of Preferred Stock shall be convertible, at any time and from time to time from and after the

Original Issue Date at the option of the Holder thereof, into that number of shares of Common Stock (subject to the limitations set

forth in Section 6(d) and Section 6(e)) determined by dividing the Stated Value of such share of Preferred Stock by the Conversion

Price. Holders shall effect conversions by providing the Corporation with the form of conversion notice attached hereto as Annex

A (a “Notice of Conversion”). Each Notice of Conversion shall specify the number of shares of Preferred Stock

to be converted, the number of shares of Preferred Stock owned prior to the conversion at issue, the number of shares of Preferred

Stock owned subsequent to the conversion at issue and the date on which such conversion is to be effected, which date may not be

prior to the date the applicable Holder delivers by .pdf via email such Notice of Conversion to the Corporation (such date, the

“Conversion Date”). If no Conversion Date is specified in a Notice of Conversion, the Conversion Date shall be

the date that such Notice of Conversion to the Corporation is deemed delivered hereunder. No ink-original Notice of Conversion shall

be required, nor shall any medallion guarantee (or other type of guarantee or notarization) of any Notice of Conversion form be

required. The calculations and entries set forth in the Notice of Conversion shall control in the absence of manifest or

mathematical error. To effect conversions of shares of Preferred Stock, a Holder shall not be required to surrender the

certificate(s) representing the shares of Preferred Stock to the Corporation unless all of the shares of Preferred Stock represented

thereby are so converted, in which case such Holder shall deliver the certificate representing such shares of Preferred Stock

promptly following the Conversion Date at issue. Shares of Preferred Stock converted into Common Stock or redeemed in accordance

with the terms hereof shall be canceled and shall not be reissued.

b) Conversion

Price. The conversion price for the Preferred Stock shall equal $6.10, subject to adjustment herein (the “Conversion

Price”); provided that in connection with each exercise of a Greenshoe Right pursuant to Section 2.4 of the Purchase

Agreement in the event that 90% of the arithmetic average of the five (5) lowest Trading Prices during the 10 Trading Days

immediately prior to such exercise of a Greenshoe Right is less than the then Conversion Price (each such price, the

“Adjusted Price”), the Conversion Price shall thereafter be reduced to equal the Adjusted Price, subject to

further adjustment hereunder, provided further that the reduced Adjusted Price shall not, in the first instance, be subject to a

floor, provided, however, that if the Company receives written notice from Nasdaq that a floor price should be implemented, the

reduced Adjusted Price shall in all events be subject to a floor of $1.282 (the “Floor Price”) (subject to

adjustment for reverse and forward stock splits, recapitalizations and similar transactions following the Original Issue Date and

provided that if (i) the Company has received written notice from Nasdaq that a floor price should be implemented and (ii) the

Adjusted Price is less than the Floor Price, then the Adjusted Price shall equal the Floor Price). The Corporation shall give

written notice to all Holders within one Trading Day of the receipt of each such exercise of a Greenshoe Right along with the

Adjusted Price.

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c)

Mechanics of Conversion.

i. Delivery

of Conversion Shares Upon Conversion. Not later than the earlier of (i) on (1) Trading Day and (ii) the number of Trading Days

comprising the Standard Settlement Period (as defined below) after each Conversion Date (the “Share Delivery

Date”), the Corporation shall deliver, or cause to be delivered, to the converting Holder (A) the number of Conversion

Shares being acquired upon the conversion of the Preferred Stock (including, if the Corporation has given continuous notice pursuant

to Section 3(b) for payment of dividends in shares of Common Stock at least 10 Trading Days prior to the date on which the Notice of

Conversion is delivered to the Corporation, shares of Common Stock representing the payment of accrued dividends otherwise

determined pursuant to Section 3(a) but assuming that the Dividend Notice Period is the 10 Trading Days-period immediately prior to

the date on which the Notice of Conversion is delivered to the Corporation and excluding for such issuance the condition that the

Corporation deliver the Dividend Share Amount as to such dividend payment prior to the commencement of the Dividend Notice Period)

which, on or after the earlier of (i) the six month anniversary of the Original Issue Date or (ii) the Effective Date (with respect

to the shares of Common Stock registered for resale pursuant to a Conversion Shares Registration Statement), shall be free of

restrictive legends and trading restrictions (other than those which may then be required by the Purchase Agreement), and (B) a bank

check in the amount of accrued and unpaid dividends (if the Corporation has elected or is required to pay accrued dividends in

cash). On or after the earlier of (i) the six month anniversary of the Original Issue Date or (ii) the Effective Date (with respect

to the shares of Common Stock registered for resale pursuant to a Conversion Shares Registration Statement), the Corporation shall

deliver the Conversion Shares required to be delivered by the Corporation under this Section 6 electronically through the Depository

Trust Company or another established clearing corporation performing similar functions. As used herein, “Standard

Settlement Period” means the standard settlement period, expressed in a number of Trading Days, on the Corporation’s

primary Trading Market with respect to the Common Stock as in effect on the date of delivery of the Notice of Conversion.

ii. Failure

to Deliver Conversion Shares. If, in the case of any Notice of Conversion, such Conversion Shares are not delivered to or as

directed by the applicable Holder by the Share Delivery Date, the Holder shall be entitled to elect by written notice to the

Corporation at any time on or before its receipt of such Conversion Shares, to rescind such Conversion, in which event the

Corporation shall promptly return to the Holder any original Preferred Stock certificate delivered to the Corporation and the Holder

shall promptly return to the Corporation the Conversion Shares issued to such Holder pursuant to the rescinded Notice of

Conversion.

iii. Obligation

Absolute; Partial Liquidated Damages. The Corporation’s obligation to issue and deliver the Conversion Shares upon

conversion of Preferred Stock in accordance with the terms hereof are absolute and unconditional, irrespective of any action or

inaction by a Holder to enforce the same, any waiver or consent with respect to any provision hereof, the recovery of any judgment

against any Person or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation or termination, or any

breach or alleged breach by such Holder or any other Person of any obligation to the Corporation or any violation or alleged

violation of law by such Holder or any other person, and irrespective of any other circumstance which might otherwise limit such

obligation of the Corporation to such Holder in connection with the issuance of such Conversion Shares; provided, however,

that such delivery shall not operate as a waiver by the Corporation of any such action that the Corporation may have against such

Holder. In the event a Holder shall elect to convert any or all of the Stated Value of its Preferred Stock, the Corporation may not

refuse conversion based on any claim that such Holder or any one associated or affiliated with such Holder has been engaged in any

violation of law, agreement or for any other reason, unless an injunction from a court, on notice to Holder, restraining and/or

enjoining conversion of all or part of the Preferred Stock of such Holder shall have been sought and obtained, and the Corporation

posts a surety bond for the benefit of such Holder in the amount of 150% of the Stated Value of Preferred Stock which is subject to

the injunction, which bond shall remain in effect until the completion of arbitration/litigation of the underlying dispute and the

proceeds of which shall be payable to such Holder to the extent it obtains judgment. In the absence of such injunction, the

Corporation shall issue Conversion Shares and, if applicable, cash, upon a properly noticed conversion. If the Corporation fails to

deliver to a Holder such Conversion Shares pursuant to Section 6(c)(i) by the Share Delivery Date applicable to such conversion, the

Corporation shall pay to such Holder, in cash, as liquidated damages and not as a penalty, for each $5,000 of Stated Value of

Preferred Stock being converted, $50 per Trading Day (increasing to $100 per Trading Day on the third Trading Day and increasing to

$200 per Trading Day on the sixth Trading Day after the Share Delivery Date) for each Trading Day after the Share Delivery Date

until such Conversion Shares are delivered or Holder rescinds such conversion. Nothing herein shall limit a Holder’s right to

pursue actual damages for the Corporation’s failure to deliver Conversion Shares within the period specified herein and such

Holder shall have the right to pursue all remedies available to it hereunder, at law or in equity including, without limitation, a

decree of specific performance and/or injunctive relief. The exercise of any such rights shall not prohibit a Holder from seeking to

enforce damages pursuant to any other Section hereof or under applicable law.

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iv. Compensation

for Buy-In on Failure to Timely Deliver Conversion Shares Upon Conversion. In addition to any other rights available to the

Holder, if the Corporation fails for any reason to deliver to a Holder the applicable Conversion Shares by the Share Delivery Date

pursuant to Section 6(c)(i), and if after such Share Delivery Date such Holder is required by its brokerage firm to purchase (in an

open market transaction or otherwise), or the Holder’s brokerage firm otherwise purchases, shares of Common Stock to deliver

in satisfaction of a sale by such Holder of the Conversion Shares which such Holder was entitled to receive upon the conversion

relating to such Share Delivery Date (a “Buy-In”), then the Corporation shall (A) pay in cash to such Holder (in

addition to any other remedies available to or elected by such Holder) the amount, if any, by which (x) such Holder’s total

purchase price (including any brokerage commissions) for the Common Stock so purchased exceeds (y) the product of (1) the aggregate

number of shares of Common Stock that such Holder was entitled to receive from the conversion at issue multiplied by (2) the actual

sale price at which the sell order giving rise to such purchase obligation was executed (including any brokerage commissions) and

(B) at the option of such Holder, either reissue (if surrendered) the shares of Preferred Stock equal to the number of shares of

Preferred Stock submitted for conversion (in which case, such conversion shall be deemed rescinded) or deliver to such Holder the

number of shares of Common Stock that would have been issued if the Corporation had timely complied with its delivery requirements

under Section 6(c)(i). For example, if a Holder purchases shares of Common Stock having a total purchase price of $11,000 to cover a

Buy-In with respect to an attempted conversion of shares of Preferred Stock with respect to which the actual sale price of the

Conversion Shares (including any brokerage commissions) giving rise to such purchase obligation was a total of $10,000 under clause

(A) of the immediately preceding sentence, the Corporation shall be required to pay such Holder $1,000. The Holder shall provide the

Corporation written notice indicating the amounts payable to such Holder in respect of the Buy-In and, upon request of the

Corporation, evidence of the amount of such loss. Nothing herein shall limit a Holder’s right to pursue any other remedies

available to it hereunder, at law or in equity including, without limitation, a decree of specific performance and/or injunctive

relief with respect to the Corporation’s failure to timely deliver the Conversion Shares upon conversion of the shares of

Preferred Stock as required pursuant to the terms hereof.

v.

Reservation of Shares Issuable Upon Conversion. The Corporation covenants that it will at all times reserve and keep available

out of its authorized and unissued shares of Common Stock for the sole purpose of issuance upon conversion of the Preferred Stock and

payment of dividends on the Preferred Stock, each as herein provided, free from preemptive rights or any other actual contingent purchase

rights of Persons other than the Holder (and the other holders of the Preferred Stock), not less than the Required Minimum (as defined

in the Purchase Agreement). The Corporation covenants that all shares of Common Stock that shall be so issuable shall, upon issue, be

duly authorized, validly issued, fully paid and nonassessable and, if a Conversion Shares Registration Statement is then effective under

the Securities Act, shall be registered for public resale to the extent covered by and in accordance with such Conversion Shares Registration

Statement (subject to such Holder’s compliance with its obligations under the Registration Rights Agreement).

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vi.

Fractional Shares. No fractional shares or scrip representing fractional shares shall be issued upon the conversion of the Preferred

Stock. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such conversion, the Corporation shall

at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the

Conversion Price or round up to the next whole share. Notwithstanding anything to the contrary contained herein, but consistent with

the provisions of this subsection with respect to fractional Conversion Shares, nothing shall prevent any Holder from converting fractional

shares of Preferred Stock.

vii.

Transfer Taxes and Expenses. The issuance of Conversion Shares on conversion of this Preferred Stock shall be made without charge

to any Holder for any documentary stamp or similar taxes that may be payable in respect of the issue or delivery of such Conversion Shares,

provided that the Corporation shall not be required to pay any tax that may be payable in respect of any transfer involved in the issuance

and delivery of any such Conversion Shares upon conversion in a name other than that of the Holders of such shares of Preferred Stock

and the Corporation shall not be required to issue or deliver such Conversion Shares unless or until the Person or Persons requesting

the issuance thereof shall have paid to the Corporation the amount of such tax or shall have established to the satisfaction of the Corporation

that such tax has been paid. The Corporation shall pay all Transfer Agent fees required for same-day processing of any Notice of Conversion

and all fees to the Depository Trust Company (or another established clearing corporation performing similar functions) required for

same-day electronic delivery of the Conversion Shares.

d) Beneficial

Ownership Limitation. The Corporation shall not effect any conversion of the Preferred Stock, and a Holder shall not have the

right to convert any portion of the Preferred Stock, to the extent that, after giving effect to the conversion set forth on the

applicable Notice of Conversion, such Holder (together with such Holder’s Affiliates, and any Persons acting as a group

together with such Holder or any of such Holder’s Affiliates (such Persons, “Attribution Parties”)) would

beneficially own in excess of the Beneficial Ownership Limitation (as defined below).  For purposes of the foregoing sentence,

the number of shares of Common Stock beneficially owned by such Holder and its Affiliates and Attribution Parties shall include the

number of shares of Common Stock issuable upon conversion of the Preferred Stock with respect to which such determination is being

made, but shall exclude the number of shares of Common Stock which are issuable upon (i) conversion of the remaining, unconverted

Stated Value of Preferred Stock beneficially owned by such Holder or any of its Affiliates or Attribution Parties and (ii) exercise

or conversion of the unexercised or unconverted portion of any other securities of the Corporation subject to a limitation on

conversion or exercise analogous to the limitation contained herein (including, without limitation, the Preferred Stock or the

Warrants) beneficially owned by such Holder or any of its Affiliates or Attribution Parties.  Except as set forth in the

preceding sentence, for purposes of this Section 6(d), beneficial ownership shall be calculated in accordance with Section 13(d) of

the Exchange Act and the rules and regulations promulgated thereunder. To the extent that the limitation contained in this Section

6(d) applies, the determination of whether the Preferred Stock is convertible (in relation to other securities owned by such Holder

together with any Affiliates and Attribution Parties) and of how many shares of Preferred Stock are convertible shall be in the sole

discretion of such Holder, and the submission of a Notice of Conversion shall be deemed to be such Holder’s determination of

whether the shares of Preferred Stock may be converted (in relation to other securities owned by such Holder together with any

Affiliates and Attribution Parties) and how many shares of the Preferred Stock are convertible, in each case subject to the

Beneficial Ownership Limitation. To ensure compliance with this restriction, each Holder will be deemed to represent to the

Corporation each time it delivers a Notice of Conversion that such Notice of Conversion has not violated the restrictions set forth

in this paragraph and the Corporation shall have no obligation to verify or confirm the accuracy of such determination. In addition,

a determination as to any group status as contemplated above shall be determined in accordance with Section 13(d) of the Exchange

Act and the rules and regulations promulgated thereunder. For purposes of this Section 6(d), in determining the number of

outstanding shares of Common Stock, a Holder may rely on the number of outstanding shares of Common Stock as stated in the most

recent of the following: (i) the Corporation’s most recent periodic or annual report filed with the Commission, as the case

may be, (ii) a more recent public announcement by the Corporation or (iii) a more recent written notice by the Corporation or the

Transfer Agent setting forth the number of shares of Common Stock outstanding.  Upon the written or oral request of a Holder,

the Corporation shall within one Trading Day confirm orally and in writing to such Holder the number of shares of Common Stock then

outstanding.  In any case, the number of outstanding shares of Common Stock shall be determined after giving effect to the

conversion or exercise of securities of the Corporation, including the Preferred Stock, by such Holder or its Affiliates or

Attribution Parties since the date as of which such number of outstanding shares of Common Stock was reported. The

“Beneficial Ownership Limitation” shall be 9.99% of the number of shares of the Common Stock outstanding

immediately after giving effect to the issuance of shares of Common Stock issuable upon conversion of Preferred Stock held by the

applicable Holder. A Holder, upon notice to the Corporation, may increase or decrease the Beneficial Ownership Limitation provisions

of this Section 6(d) applicable to its Preferred Stock provided that the Beneficial Ownership Limitation in no event exceeds 9.99%

of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock

upon conversion of this Preferred Stock held by the Holder and the provisions of this Section 6(d) shall continue to apply. Any such

increase in the Beneficial Ownership Limitation will not be effective until the 61st day after such notice is delivered

to the Corporation and shall only apply to such Holder and no other Holder. The provisions of this paragraph shall be construed and

implemented in a manner otherwise than in strict conformity with the terms of this Section 6(d) to correct this paragraph (or any

portion hereof) which may be defective or inconsistent with the intended Beneficial Ownership Limitation contained herein or to make

changes or supplements necessary or desirable to properly give effect to such limitation. The limitations contained in this

paragraph shall apply to a successor holder of Preferred Stock.

15

e) Issuance

Limitations. Notwithstanding anything herein to the contrary, if the Corporation has not obtained Shareholder Approval, then the

Corporation may not issue, upon conversion of the Preferred Stock, a number of shares of Common Stock which, when aggregated with

any shares of Common Stock issued on or after the Original Issue Date and prior to such Conversion Date (i) in connection with any

conversion of Preferred Stock issued pursuant to the Purchase Agreement, (ii) in connection with the exercise of any Warrants issued

pursuant to the Purchase Agreement and (iii) in connection with the exercise of any warrants issued to any registered broker-dealer

as a fee in connection with the issuance of the Securities pursuant to the Purchase Agreement, would exceed 360,695 shares of Common

Stock (subject to adjustment for forward and reverse stock splits, recapitalizations and the like) (such number of shares, the

“Issuable Maximum”). Each Holder shall be entitled to a portion of the Issuable Maximum equal to the quotient

obtained by dividing (x) the original Stated Value of such Holder’s Preferred Stock by (y) the aggregate Stated Value of all

Preferred Stock issued on the Original Issue Date to all Holders. In addition, each Holder may allocate its pro-rata portion of the

Issuable Maximum among Preferred Stock and Warrants held by it in its sole discretion. Such portion shall be adjusted upward ratably

in the event a Holder no longer holds any Preferred Stock or Warrants and the amount of shares issued to such Holder pursuant to

such Holder’s Preferred Stock and Warrants was less than such Holder’s pro-rata share of the Issuable Maximum. For

avoidance of doubt, unless and until any required Shareholder Approval is obtained and effective, warrants issued to any registered

broker-dealer as a fee in connection with the Securities issued pursuant to the Purchase Agreement as described in clause (iii)

above shall provide that such warrants shall not be allocated any portion of the Issuable Maximum and shall be unexercisable unless

and until such Shareholder Approval is obtained and effective.

Section

7. Certain Adjustments.

a)

Stock Dividends and Stock Splits. If the Corporation, at any time while this Preferred Stock is outstanding: (i) pays a stock

dividend or otherwise makes a distribution or distributions payable in shares of Common Stock on shares of Common Stock or any other

Common Stock Equivalents (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Corporation upon

conversion of, or payment of a dividend on, this Preferred Stock), (ii) subdivides outstanding shares of Common Stock into a larger number

of shares, (iii) combines (including by way of a reverse stock split) outstanding shares of Common Stock into a smaller number of shares,

or (iv) issues, in the event of a reclassification of shares of the Common Stock, any shares of capital stock of the Corporation, then

the Conversion Price shall be multiplied by a fraction of which the numerator shall be the number of shares of Common Stock (excluding

any treasury shares of the Corporation) outstanding immediately before such event, and of which the denominator shall be the number of

shares of Common Stock outstanding immediately after such event. Any adjustment made pursuant to this Section 7(a) shall become effective

immediately after the record date for the determination of stockholders entitled to receive such dividend or distribution and shall become

effective immediately after the effective date in the case of a subdivision, combination or re-classification.

b)

Subsequent Equity Sales. If, at any time while this Preferred Stock is outstanding, the Corporation or any Subsidiary, as applicable,

sells or grants any option to purchase or sells or grants any right to reprice, or otherwise disposes of or issues (or announces any

sale, grant or any option to purchase or other disposition), any Common Stock or Common Stock Equivalents entitling any Person to acquire

shares of Common Stock at an effective price per share that is lower than the then Conversion Price (such lower price, the “Base

Conversion Price” and such issuances, collectively, a “Dilutive Issuance”) (if the holder of the Common

Stock or Common Stock Equivalents so issued shall at any time, whether by operation of purchase price adjustments, reset provisions,

floating conversion, exercise or exchange prices or otherwise, or due to warrants, options or rights per share which are issued in connection

with such issuance, be entitled to receive shares of Common Stock at an effective price per share that is lower than the Conversion Price,

such issuance shall be deemed to have occurred for less than the Conversion Price on such date of the Dilutive Issuance), then simultaneously

with the consummation (or, if earlier, the announcement) of each Dilutive Issuance the Conversion Price shall be reduced to equal the

Base Conversion Price. Notwithstanding the foregoing, no adjustment will be made under this Section 7(b) in respect of an Exempt Issuance.

If the Corporation enters into a Variable Rate Transaction, despite the prohibition set forth in the Purchase Agreement, the Corporation

shall be deemed to have issued Common Stock or Common Stock Equivalents at the lowest possible conversion price at which such securities

may be converted or exercised. The Corporation shall notify the Holders in writing, no later than the Trading Day following the issuance

of any Common Stock or Common Stock Equivalents subject to this Section 7(b), indicating therein the applicable issuance price, or applicable

reset price, exchange price, conversion price and other pricing terms (such notice, the “Dilutive Issuance Notice”).

For purposes of clarification, whether or not the Corporation provides a Dilutive Issuance Notice pursuant to this Section 7(b), upon

the occurrence of any Dilutive Issuance, the Holders are entitled to receive a number of Conversion Shares based upon the Base Conversion

Price on or after the date of such Dilutive Issuance, regardless of whether a Holder accurately refers to the Base Conversion Price in

the Notice of Conversion. In addition, notwithstanding anything to the contrary contained herein, whether or not the Corporation provides

a Dilutive Issuance Notice pursuant to this Section 7(b), to the extent a Holder submits a Notice of Conversion on the Trading Day on

which a Dilutive Issuance is triggered, but prior to the time at which such Dilutive Issuance is effected, the Holder shall be entitled

to receive, no later than the Trading Day following the date such Dilutive Issuance is triggered, such additional number of Conversion

Shares equal to the difference between: (i) the Conversion Amount stated in the Notice of Conversion submitted on such Trading Day divided

by the Base Conversion Price and (ii) the number of Conversion Shares the Holder was entitled to receive prior to such Dilutive Issuance

as set forth under “the Number of shares of Common Stock to be Issued” in the applicable Notice of Conversion.

16

c) Subsequent

Rights Offerings. In addition to any adjustments pursuant to Section 7(a) above, if at any time the Corporation grants, issues

or sells any Common Stock Equivalents or rights to purchase stock, warrants, securities or other property pro rata to the record

holders of any class of shares of Common Stock (the “Purchase Rights”), then the Holder will be entitled to

acquire, upon the terms applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if

the Holder had held the number of shares of Common Stock acquirable upon complete conversion of such Holder’s Preferred Stock

(without regard to any limitations on exercise hereof, including without limitation, the Beneficial Ownership Limitation)

immediately before the date on which a record is taken for the grant, issuance or sale of such Purchase Rights, or, if no such

record is taken, the date as of which the record holders of shares of Common Stock are to be determined for the grant, issue or sale

of such Purchase Rights (provided, however, that, to the extent that the Holder’s right to participate in any such Purchase

Right would result in the Holder exceeding the Beneficial Ownership Limitation or the Corporation’s issuance of shares in

excess of the Issuable Maximum, then the Holder shall not be entitled to participate in such Purchase Right to such extent (or

beneficial ownership of such shares of Common Stock as a result of such Purchase Right to such extent) and such Purchase Right to

such extent shall be held in abeyance for the Holder until such time, if ever, as its right thereto would not result in the Holder

exceeding the Beneficial Ownership Limitation or the Corporation’s issuance of shares in excess of the Issuable

Maximum).

d) Pro

Rata Distributions. During such time as this Preferred Stock is outstanding, if the Corporation declares or makes any dividend

or other distribution of its assets (or rights to acquire its assets) to holders of shares of Common Stock, by way of return of

capital or otherwise (including, without limitation, any distribution of cash, stock or other securities, property or options by way

of a dividend, spin off, reclassification, corporate rearrangement, scheme of arrangement or other similar transaction) (a

“Distribution”), at any time after the issuance of this Preferred Stock, then, in each such case, the Holder

shall be entitled to participate in such Distribution to the same extent that the Holder would have participated therein if the

Holder had held the number of shares of Common Stock acquirable upon complete conversion of this Preferred Stock (without regard to

any limitations on conversion hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date

of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the record holders of shares

of Common Stock are to be determined for the participation in such Distribution (provided, however, to the extent that

the Holder’s right to participate in any such Distribution would result in the Holder exceeding the Beneficial Ownership

Limitation or the Corporation’s issuance of shares in excess of the Issuable Maximum, then the Holder shall not be entitled to

participate in such Distribution to such extent (or in the beneficial ownership of any shares of Common Stock as a result of such

Distribution to such extent) and the portion of such Distribution shall be held in abeyance for the benefit of the Holder until such

time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation or the

Corporation’s issuance of shares in excess of the Issuable Maximum).

17

e)

Fundamental Transaction. If, at any time while this Preferred Stock is outstanding, (i) the Corporation, directly or indirectly,

in one or more related transactions effects any merger or consolidation of the Corporation with or into another Person, (ii) the Corporation

(and all of its Subsidiaries, taken as a whole), directly or indirectly, effects any sale, lease, license, assignment, transfer, conveyance

or other disposition of all or substantially all of its assets in one or a series of related transactions, (iii) any, direct or indirect,

purchase offer, tender offer or exchange offer (whether by the Corporation or another Person) is completed pursuant to which holders

of Common Stock are permitted to sell, tender or exchange their shares for other securities, cash or property and has been accepted by

the holders of 50% or more of the outstanding Common Stock, (iv) the Corporation, directly or indirectly, in one or more related transactions

effects any reclassification, reorganization or recapitalization of the Common Stock or any compulsory share exchange pursuant to which

the Common Stock is effectively converted into or exchanged for other securities, cash or property, or (v) the Corporation, directly

or indirectly, in one or more related transactions consummates a stock or share purchase agreement or other business combination (including,

without limitation, a reorganization, recapitalization, spin-off or scheme of arrangement) with another Person whereby such other Person

acquires more than 50% of the outstanding shares of Common Stock (each a “Fundamental Transaction”), then, upon any

subsequent conversion of this Preferred Stock, the Holder shall have the right to receive, for each Conversion Share that would have

been issuable upon such conversion immediately prior to the occurrence of such Fundamental Transaction (without regard to any limitation

in Section 6(d) and Section 6(e) on the conversion of this Preferred Stock), the number of shares of Common Stock of the successor or

acquiring corporation or of the Corporation, if it is the surviving corporation, and any additional consideration (the “Alternate

Consideration”) receivable as a result of such Fundamental Transaction by a holder of the number of shares of Common Stock

for which this Preferred Stock is convertible immediately prior to such Fundamental Transaction (without regard to any limitation in

Section 6(d) and Section 6(e) on the conversion of this Preferred Stock). For purposes of any such conversion, the determination of the

Conversion Price shall be appropriately adjusted to apply to such Alternate Consideration based on the amount of Alternate Consideration

issuable in respect of one share of Common Stock in such Fundamental Transaction, and the Corporation shall apportion the Conversion

Price among the Alternate Consideration in a reasonable manner reflecting the relative value of any different components of the Alternate

Consideration. If holders of Common Stock are given any choice as to the securities, cash or property to be received in a Fundamental

Transaction, then the Holder shall be given the same choice as to the Alternate Consideration it receives upon any conversion of this

Preferred Stock following such Fundamental Transaction. To the extent necessary to effectuate the foregoing provisions, any successor

to the Corporation or surviving entity in such Fundamental Transaction shall file a new Certificate of Designation with the same terms

and conditions and issue to the Holders new preferred stock consistent with the foregoing provisions and evidencing the Holders’

right to convert such preferred stock into Alternate Consideration. The Corporation shall cause any successor entity in a Fundamental

Transaction in which the Corporation is not the survivor (the “Successor Entity”) to assume in writing all of the

obligations of the Corporation under this Certificate of Designation and the other Transaction Documents (as defined in the Purchase

Agreement) in accordance with the provisions of this Section 7(e) pursuant to written agreements in form and substance reasonably satisfactory

to the Holder and approved by the Holder (without unreasonable delay) prior to such Fundamental Transaction and shall, at the option

of the holder of this Preferred Stock, deliver to the Holder in exchange for this Preferred Stock a security of the Successor Entity

evidenced by a written instrument substantially similar in form and substance to this Preferred Stock which is convertible for a corresponding

number of shares of capital stock of such Successor Entity (or its parent entity) equivalent to the shares of Common Stock acquirable

and receivable upon conversion of this Preferred Stock (without regard to any limitations on the conversion of this Preferred Stock)

prior to such Fundamental Transaction, and with a conversion price which applies the conversion price hereunder to such shares of capital

stock (but taking into account the relative value of the shares of Common Stock pursuant to such Fundamental Transaction and the value

of such shares of capital stock, such number of shares of capital stock and such conversion price being for the purpose of protecting

the economic value of this Preferred Stock immediately prior to the consummation of such Fundamental Transaction), and which is reasonably

satisfactory in form and substance to the Holder. Upon the occurrence of any such Fundamental Transaction, the Successor Entity shall

succeed to, and be substituted for (so that from and after the date of such Fundamental Transaction, the provisions of this Certificate

of Designation and the other Transaction Documents referring to the “Corporation” shall refer instead to the Successor Entity),

and may exercise every right and power of the Corporation and shall assume all of the obligations of the Corporation under this Certificate

of Designation and the other Transaction Documents with the same effect as if such Successor Entity had been named as the Corporation

herein.

18

f)

Calculations. All calculations under this Section 7 shall be made to the nearest cent or the nearest 1/100th of a share, as the

case may be. For purposes of this Section 7, the number of shares of Common Stock deemed to be issued and outstanding as of a given date

shall be the sum of the number of shares of Common Stock (excluding any treasury shares of the Corporation) issued and outstanding.

g)

Notice to the Holders.

i.

Adjustment to Conversion Price. Whenever the Conversion Price is adjusted pursuant to any provision of this Section 7, the Corporation

shall promptly deliver to each Holder by email a notice setting forth the Conversion Price after such adjustment and setting forth a

brief statement of the facts requiring such adjustment.

ii. Notice

to Allow Conversion by Holder. If (A) the Corporation shall declare a dividend (or any other distribution in whatever form) on

the Common Stock, (B) the Corporation shall declare a special nonrecurring cash dividend on or a redemption of the Common Stock, (C)

the Corporation shall authorize the granting to all holders of the Common Stock of rights or warrants to subscribe for or purchase

any shares of capital stock of any class or of any rights, (D) the approval of any stockholders of the Corporation shall be required

in connection with any reclassification of the Common Stock, any consolidation or merger to which the Corporation is a party, any

sale or transfer of all or substantially all of the assets of the Corporation (and all of its Subsidiaries, taken as a whole), or

any compulsory share exchange whereby the Common Stock is converted into other securities, cash or property or (E) the Corporation

shall authorize the voluntary or involuntary dissolution, liquidation or winding up of the affairs of the Corporation, then, in each

case, the Corporation shall cause to be filed at each office or agency maintained for the purpose of conversion of this Preferred

Stock, and shall cause to be delivered by email to each Holder at its last email address as it shall appear upon the stock books of

the Corporation, at least twenty (20) calendar days prior to the applicable record or effective date hereinafter specified, a notice

stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution, redemption, rights or

warrants, or if a record is not to be taken, the date as of which the holders of the Common Stock of record to be entitled to such

dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on which such reclassification,

consolidation, merger, sale, transfer or share exchange is expected to become effective or close, and the date as of which it is

expected that holders of the Common Stock of record shall be entitled to exchange their shares of the Common Stock for securities,

cash or other property deliverable upon such reclassification, consolidation, merger, sale, transfer or share exchange, provided

that the failure to deliver such notice or any defect therein or in the delivery thereof shall not affect the validity of the

corporate action required to be specified in such notice. To the extent that any notice provided hereunder constitutes, or contains,

material, non-public information regarding the Corporation or any of the Subsidiaries, the Corporation shall simultaneously file

such notice with the Commission pursuant to a Current Report on Form 8-K. The Holder shall remain entitled to convert the Conversion

Amount of this Preferred Stock (or any part hereof) during the 20-day period commencing on the date of such notice through the

effective date of the event triggering such notice except as may otherwise be expressly set forth herein.

19

Section

8. Negative Covenants. As long as any shares of Preferred Stock are outstanding, unless the Required Holders shall have

otherwise given prior written consent, the Corporation shall not, and shall not permit any of the Subsidiaries to, directly or indirectly:

a)

other than Permitted Indebtedness, enter into, create, incur, assume, guarantee or suffer to exist any Indebtedness;

b)

other than Permitted Liens, enter into, create, incur, assume or suffer to exist any Liens of any kind, on or with respect to any of

its property or assets now owned or hereafter acquired or any interest therein or any income or profits therefrom;

c)

amend its charter documents, including, without limitation, its certificate of incorporation and bylaws, in any manner that

materially and adversely affects any rights of the Holder;

d)

repay, repurchase or offer to repay, repurchase or otherwise acquire more than a de minimis number of shares of its Common

Stock, Common Stock Equivalents or Junior Securities, other than as to (i) the Conversion Shares or Warrant Shares as permitted or

required under the Transaction Documents and (ii) repurchases of Common Stock or Common Stock Equivalents of departing officers and

directors of the Corporation, provided that such repurchases shall not exceed an aggregate of $100,000 for all officers and

directors for so long as the Preferred Stock is outstanding;

e)

pay cash dividends or distributions on Junior Securities of the Corporation;

f)

enter into any transaction with any Affiliate of the Corporation which would be required to be disclosed in any public filing with

the Commission, unless such transaction is made on an arm’s-length basis and expressly approved by a majority of the

disinterested directors of the Corporation (even if less than a quorum otherwise required for board approval);

g)

enter into any factoring agreement, merchant cash advance agreement, revenue-based financing or similar arrangement whereby the

Corporation receives funds from any third party against future product or services sales.

h)

enter into any agreement with respect to any of the foregoing.

Section

9. Miscellaneous.

a)

Notices. Any and all notices or other communications or deliveries to be provided by the Holders hereunder including, without

limitation, any Notice of Conversion, shall be in writing and delivered personally, by e-mail attachment, or sent by a nationally recognized

overnight courier service, addressed to the Corporation, at 505 Montgomery Street, 10th Floor, San Francisco, CA 94111, Attention:

Secretary, e-mail address Alan.Urban@gtbiopharma.com, or such other e-mail address or address as the Corporation may specify for such

purposes by notice to the Holders delivered in accordance with this Section 9. Any and all notices or other communications or deliveries

to be provided by the Corporation hereunder shall be in writing and delivered personally, by e-mail attachment, or sent by a nationally

recognized overnight courier service addressed to each Holder at the e-mail address or address of such Holder appearing on the books

of the Corporation, or if no such e-mail address or address appears on the books of the Corporation, at the principal place of business

of such Holder, as set forth in the Purchase Agreement. Any notice or other communication or deliveries hereunder shall be deemed given

and effective on the earliest of (i) the date of transmission, if such notice or communication is delivered via e-mail attachment at

the e-mail address set forth in this Section prior to 5:30 p.m. (New York City time) on any date, (ii) the next Trading Day after the

date of transmission, if such notice or communication is delivered via e-mail attachment at the e-mail address set forth in this Section

on a day that is not a Trading Day or later than 5:30 p.m. (New York City time) on any Trading Day, (iii) the second Trading Day following

the date of mailing, if sent by U.S. nationally recognized overnight courier service, or (iv) upon actual receipt by the party to whom

such notice is required to be given.

20

b)

Absolute Obligation. Except as expressly provided herein, no provision of this Certificate of Designation shall alter or impair

the obligation of the Corporation, which is absolute and unconditional, to pay liquidated damages, accrued dividends and accrued interest,

as applicable, on the shares of Preferred Stock at the time, place, and rate, and in the coin or currency, herein prescribed.

c)

Lost or Mutilated Preferred Stock Certificate. If a Holder’s Preferred Stock certificate shall be mutilated, lost, stolen

or destroyed, the Corporation shall execute and deliver, in exchange and substitution for and upon cancellation of a mutilated certificate,

or in lieu of or in substitution for a lost, stolen or destroyed certificate, a new certificate for the shares of Preferred Stock so

mutilated, lost, stolen or destroyed, but only upon receipt of evidence of such loss, theft or destruction of such certificate, and of

the ownership hereof reasonably satisfactory to the Corporation.

d)

Governing Law. All questions concerning the construction, validity, enforcement and interpretation of this Certificate of Designation

shall be governed by and construed and enforced in accordance with the internal laws of the State of Delaware, without regard to the

principles of conflict of laws thereof. All legal proceedings concerning the interpretation, enforcement and defense of the transactions

contemplated by any of the Transaction Documents (whether brought against a party hereto or its respective Affiliates, directors, officers,

shareholders, employees or agents) shall be commenced in the state and federal courts sitting in the City of New York, Borough of Manhattan

(the “New York Courts”). The Corporation and each Holder hereby irrevocably submits to the exclusive jurisdiction

of the New York Courts for the adjudication of any dispute hereunder or in connection herewith or with any transaction contemplated hereby

or discussed herein (including with respect to the enforcement of any of the Transaction Documents), and hereby irrevocably waives, and

agrees not to assert in any suit, action or proceeding, any claim that it is not personally subject to the jurisdiction of such New York

Courts, or such New York Courts are improper or inconvenient venue for such proceeding. The Corporation and each Holder hereby irrevocably

waives personal service of process and consents to process being served in any such suit, action or proceeding by mailing a copy thereof

via registered or certified mail or overnight delivery (with evidence of delivery) to such party at the address in effect for notices

to it under this Certificate of Designation and agrees that such service shall constitute good and sufficient service of process and

notice thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process in any other manner permitted

by applicable law. The Corporation and each Holder hereby irrevocably waives, to the fullest extent permitted by applicable law, any

and all right to trial by jury in any legal proceeding arising out of or relating to this Certificate of Designation or the transactions

contemplated hereby. If the Corporation or any Holder shall commence an action or proceeding to enforce any provisions of this Certificate

of Designation, then the prevailing party in such action or proceeding shall be reimbursed by the other party for its attorneys’

fees and other costs and expenses incurred in the investigation, preparation and prosecution of such action or proceeding.

21

e) Waiver.

Any waiver by the Corporation or a Holder of a breach of any provision of this Certificate of Designation shall not operate as or be

construed to be a waiver of any other breach of such provision or of any breach of any other provision of this Certificate of

Designation or a waiver by any other Holders. The failure of the Corporation or a Holder to insist upon strict adherence to any term

of this Certificate of Designation on one or more occasions shall not be considered a waiver or deprive that party (or any other

Holder) of the right thereafter to insist upon strict adherence to that term or any other term of this Certificate of Designation on

any other occasion. Any waiver by the Corporation or a Holder must be in writing.

f) Severability.

If any provision of this Certificate of Designation is invalid, illegal or unenforceable, the balance of this Certificate of

Designation shall remain in effect, and if any provision is inapplicable to any Person or circumstance, it shall nevertheless remain

applicable to all other Persons and circumstances. If it shall be found that any interest or other amount deemed interest due

hereunder violates the applicable law governing usury, the applicable rate of interest due hereunder shall automatically be lowered

to equal the maximum rate of interest permitted under applicable law.

g) Next

Business Day. Whenever any payment or other obligation hereunder shall be due on a day other than a Business Day, such payment

shall be made on the next succeeding Business Day.

h)

Headings. The headings contained herein are for convenience only, do not constitute a part of this Certificate of Designation

and shall not be deemed to limit or affect any of the provisions hereof.

i)

Status of Converted or Redeemed Preferred Stock. Shares of Preferred Stock may only be issued pursuant to the Purchase Agreement.

If any shares of Preferred Stock shall be converted, redeemed or reacquired by the Corporation, such shares shall resume the status of

authorized but unissued shares of preferred stock and shall no longer be designated as its Series M 10% Convertible Preferred Stock.

j) Amendments.

This Certificate of Designations or any provision thereof may be amended by obtaining the written consent of the majority of the

Holders of the Preferred Stock issued and outstanding on such date to the fullest extent permitted by the certificate of

incorporation of the Corporation then in effect and applicable Delaware law.

*********************

22

RESOLVED,

FURTHER, that the Chairman, the president or any vice-president, and the secretary or any assistant secretary, of the Corporation be

and they hereby are authorized and directed to prepare and file this Certificate of Designation of Preferences, Rights and Limitations

in accordance with the foregoing resolution and the provisions of Delaware law.

IN

WITNESS WHEREOF, the undersigned have executed this Certificate this 14th day of September, 2026.

/s/ Michael Breen

/s/ Alan Urban

Name:  Michael Breen

Name:  Alan Urban

Title: Executive Chairman and

Title: Chief Financial Officer

Chief Executive Officer

23

ANNEX

A

NOTICE

OF CONVERSION

(To

be Executed by the Registered Holder in order to Convert Shares of Preferred Stock)

The

undersigned hereby elects to convert the number of shares of Series M 10% Convertible Preferred Stock indicated below into shares of

common stock, par value $0.001 per share (the “Common Stock”), of GT Biopharma, Inc., a Delaware corporation (the

“Corporation”), according to the conditions hereof, as of the date written below. If shares of Common Stock are to

be issued in the name of a Person other than the undersigned, the undersigned will pay all transfer taxes payable with respect thereto

and is delivering herewith such certificates and opinions as may be required by the Corporation in accordance with the Purchase Agreement.

No fee will be charged to the Holders for any conversion, except for any such transfer taxes.

Conversion

calculations:

Date

to Effect Conversion: ________________________________________________________________

Number

of shares of Preferred Stock owned prior to Conversion: ___________________________________

Number

of shares of Preferred Stock to be Converted: ____________________________________________

Stated

Value of shares of Preferred Stock to be Converted: ________________________________________

Number

of shares of Common Stock to be Issued: ______________________________________________

Applicable

Conversion Price:______________________________________________________________

Number

of shares of Preferred Stock subsequent to Conversion: ____________________________________

Address

for Delivery: ______________________

or

DWAC

Instructions:

Broker

no: _________

Account

no: ___________

[HOLDER]

By:

Name:

Title:

24

EX-4.1

EX-4.1

Filename: ex4-1.htm · Sequence: 3

Exhibit

4.1

NEITHER

THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION

OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED

(THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT

UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS

OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS. THIS SECURITY AND THE SECURITIES ISSUABLE UPON EXERCISE

OF THIS SECURITY MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN SECURED BY SUCH SECURITIES.

COMMON

STOCK PURCHASE WARRANT

GT

Biopharma, Inc.

Warrant

No.: _______

Warrant

Shares: _______

Issue

Date: September 14, 2026

THIS

COMMON STOCK PURCHASE WARRANT (this “Warrant”) certifies that, for value received, _____________ or its assigns (the

“Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set

forth, at any time on or after September 14, 2026 (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New

York City time) on September 14, 2031 (the “Termination Date”) but not thereafter, to subscribe for and purchase from

GT Biopharma, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder,

the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be

equal to the Exercise Price, as defined in Section 2(b).

Section

1. Definitions. Capitalized terms used and not otherwise defined herein shall have the meanings set forth in that certain

Securities Purchase Agreement (the “Purchase Agreement”), dated September 14, 2026, among the Company and the purchasers

signatory thereto.

1

Section

2. Exercise.

a)

Exercise of Warrant. Exercise of the purchase rights represented by this Warrant may be made, in whole or in part, at any time

or times on or after the Initial Exercise Date and on or before the Termination Date by delivery to the Company of a duly executed PDF

copy submitted by e-mail (or e-mail attachment) of the Notice of Exercise in the form annexed hereto (the “Notice of Exercise”).

Within the earlier of (i) one (1) Trading Day and (ii) the number of Trading Days comprising the Standard Settlement Period (as defined

in Section 2(d)(i) herein) following the date of exercise as aforesaid, the Holder shall deliver the aggregate Exercise Price for the

shares specified in the applicable Notice of Exercise by wire transfer or cashier’s check drawn on a United States bank unless

the cashless exercise procedure specified in Section 2(c) below is specified in the applicable Notice of Exercise. No ink-original Notice

of Exercise shall be required, nor shall any medallion guarantee (or other type of guarantee or notarization) of any Notice of Exercise

be required. Notwithstanding anything herein to the contrary, the Holder shall not be required to physically surrender this Warrant to

the Company until the Holder has purchased all of the Warrant Shares available hereunder and this Warrant has been exercised in full,

in which case, the Holder shall surrender this Warrant to the Company for cancellation within three (3) Trading Days of the date on which

the final Notice of Exercise is delivered to the Company. Partial exercises of this Warrant resulting in purchases of a portion of the

total number of Warrant Shares available hereunder shall have the effect of lowering the outstanding number of Warrant Shares purchasable

hereunder in an amount equal to the applicable number of Warrant Shares purchased. The Holder and the Company shall maintain records

showing the number of Warrant Shares purchased and the date of such purchases. The Company shall deliver any objection to any Notice

of Exercise within one (1) Trading Day of receipt of such notice. The Holder and any assignee, by acceptance of this Warrant, acknowledge

and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the Warrant Shares hereunder, the

number of Warrant Shares available for purchase hereunder at any given time may be less than the amount stated on the face hereof.

b)

Exercise Price. The exercise price per share of Common Stock under this Warrant shall be $6.10, subject to adjustment hereunder

(the “Exercise Price”).

c)

Cashless Exercise. If at the time of exercise hereof there is no effective registration statement registering, or the prospectus

contained therein is not available for the resale of the Warrant Shares by the Holder, then this Warrant may also be exercised, in whole

or in part, at such time by means of a “cashless exercise” in which the Holder shall be entitled to receive a number of Warrant

Shares equal to the quotient obtained by dividing [(A-B) (X)] by (A), where:

(A) =

as applicable: (i) the VWAP on the Trading Day immediately

preceding the date of the applicable Notice of Exercise if such Notice of Exercise is (1) delivered pursuant to Section 2(a) hereof on

a day that is not a Trading Day or (2) delivered pursuant to Section 2(a) hereof on a Trading Day prior to the opening of “regular

trading hours” (as defined in Rule 600(b) of Regulation NMS promulgated under the federal securities laws) on such Trading Day,

(ii) the highest Bid Price of the Common Stock on the principal Trading Market as reported by Bloomberg L.P. (“Bloomberg”)

within two (2) hours of the time of the Holder’s delivery of the Notice of Exercise pursuant to Section 2(a) hereof if such Notice

of Exercise is delivered during “regular trading hours,” or with two (2) hours after the close of “regular trading

hours,” on a Trading Day or (iii) the VWAP on the date of the applicable Notice of Exercise if the date of such Notice of Exercise

is a Trading Day and such Notice of Exercise is delivered pursuant to Section 2(a) hereof after two (2) hours following the close of

“regular trading hours” on such Trading Day;

2

(B) =

the Exercise Price of this Warrant, as adjusted hereunder;

and

(X)

=

the number of Warrant Shares that would be issuable upon exercise of this Warrant in accordance with the terms of this Warrant if

such exercise were by means of a cash exercise rather than a cashless exercise.

If

Warrant Shares are issued in such a cashless exercise, the parties acknowledge and agree that in accordance with Section 3(a)(9) of the

Securities Act, the holding period of the Warrant Shares being issued may be tacked on to the holding period of this Warrant. The Company

agrees not to take any position contrary to this Section 2(c).

“Bid

Price” means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock

is then listed or quoted on a Trading Market, the bid price of the Common Stock for the time in question (or the nearest preceding date)

on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg (based on a Trading Day from 9:30 a.m.

(New York City time) to 4:02 p.m. (New York City time)), (b) if OTCQB or OTCQX is not a Trading Market, the volume weighted average price

of the Common Stock for such date (or the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then

listed or quoted for trading on OTCQB or OTCQX and if prices for the Common Stock are then reported on The Pink Open Market (or a similar

organization or agency succeeding to its functions of reporting prices), the most recent bid price per share of the Common Stock so reported,

or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser selected in good

faith by the Company and reasonably acceptable to the Purchasers of a majority in interest of the Securities then outstanding, the fees

and expenses of which shall be paid by the Company.

“VWAP”

means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed

or quoted on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date)

on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg (based on a Trading Day from 9:30 a.m.

(New York City time) to 4:02 p.m. (New York City time)), (b) if the OTCQB Venture Market (“OTCQB”) or the OTCQX Best

Market (“OTCQX”) is not a Trading Market, the volume weighted average price of the Common Stock for such date (or

the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then listed or quoted for trading on OTCQB

or OTCQX and if prices for the Common Stock are then reported on the Pink Open Market (“Pink Market”) operated by

the OTC Markets, Inc. (or a similar organization or agency succeeding to its functions of reporting prices), the most recent bid price

per share of the Common Stock so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined

by an independent appraiser selected in good faith by the Company and reasonably acceptable to the Purchasers of a majority in interest

of the Securities then outstanding, the fees and expenses of which shall be paid by the Company.

3

Notwithstanding

anything herein to the contrary, on the Termination Date, this Warrant shall be automatically exercised via cashless exercise pursuant

to this Section 2(c).

Notwithstanding

anything herein to the contrary, in the event that any cashless exercise pursuant to this paragraph would otherwise cause the Holder

to exceed the Beneficial Ownership Limitation, the Company shall only issue such number of Warrant Shares to the Holder that would not

cause the Holder to exceed the maximum number of Warrant Shares permitted pursuant to the Beneficial Ownership Limitation, as directed

by the Holder, with the balance to be held in abeyance until notice from the Holder that the balance (or portion thereof) may be issued

in compliance with such Beneficial Ownership Limitation.

d)

Mechanics of Exercise.

i.

Delivery of Warrant Shares Upon Exercise. The Company shall cause the Warrant Shares purchased hereunder to be transmitted by

the Transfer Agent to the Holder by crediting the account of the Holder’s or its designee’s balance account with The Depository

Trust Company through its Deposit or Withdrawal at Custodian system (“DWAC”) if the Company is then a participant

in such system and either (A) there is an effective registration statement permitting the issuance of the Warrant Shares to or resale

of the Warrant Shares by Holder or (B) the Warrant Shares are eligible for resale by the Holder without volume or manner-of-sale limitations

pursuant to Rule 144 (assuming cashless exercise of this Warrant), and otherwise by physical delivery of a certificate, registered in

the Company’s share register in the name of the Holder or its designee, for the number of Warrant Shares to which the Holder is

entitled pursuant to such exercise to the address specified by the Holder in the Notice of Exercise by the date that is the earlier of

(i) one (1) Trading Day after the delivery to the Company of the Notice of Exercise and (ii) the number of Trading Days comprising the

Standard Settlement Period after the delivery to the Company of the Notice of Exercise (such date, the “Warrant Share Delivery

Date”); provided, however, that the aggregate Exercise Price has been delivered to the Company by the Warrant Share Delivery

Date. Upon delivery of the Notice of Exercise, the Holder shall be deemed for all corporate purposes to have become the holder of record

of the Warrant Shares with respect to which this Warrant has been exercised, irrespective of the date of delivery of the Warrant Shares,

provided that payment of the aggregate Exercise Price (other than in the case of a cashless exercise) is received within the earlier

of (i) one (1) Trading Day and (ii) the number of Trading Days comprising the Standard Settlement Period following delivery of the Notice

of Exercise. If the Holder duly exercises this Warrant pursuant to Section 2(a) hereof and the Company fails for any reason to deliver

to the Holder the Warrant Shares subject to a Notice of Exercise by the Warrant Share Delivery Date, the Company shall pay to the Holder,

in cash, as liquidated damages and not as a penalty, for each $1,000 of Warrant Shares subject to such exercise (based on the VWAP of

the Common Stock on the date of the applicable Notice of Exercise), $10 per Trading Day (increasing to $20 per Trading Day on the third

Trading Day after the Warrant Share Delivery Date) for each Trading Day after such Warrant Share Delivery Date until such Warrant Shares

are delivered or Holder rescinds such exercise. The Company agrees to maintain a transfer agent that is a participant in the FAST program

so long as this Warrant remains outstanding and exercisable. As used herein, “Standard Settlement Period” means the

standard settlement period, expressed in a number of Trading Days, on the Company’s primary Trading Market with respect to the

Common Stock as in effect on the date of delivery of the Notice of Exercise.

4

ii.

Delivery of New Warrants Upon Exercise. If this Warrant shall have been exercised in part, the Company shall, at the request of

a Holder and upon surrender of this Warrant certificate, at the time of delivery of the Warrant Shares, deliver to the Holder a new Warrant

evidencing the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant, which new Warrant shall in

all other respects be identical with this Warrant.

iii.

Rescission Rights. If the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares pursuant to Section

2(d)(i) by the Warrant Share Delivery Date, then the Holder will have the right to rescind such exercise.

iv.

Compensation for Buy-In on Failure to Timely Deliver Warrant Shares Upon Exercise. In addition to any other rights available to

the Holder, if the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares in accordance with the provisions

of Section 2(d)(i) above pursuant to an exercise on or before the Warrant Share Delivery Date, and if after such date the Holder is required

by its broker to purchase (in an open market transaction or otherwise) or the Holder’s brokerage firm otherwise purchases, shares

of Common Stock to deliver in satisfaction of a sale by the Holder of the Warrant Shares which the Holder anticipated receiving upon

such exercise (a “Buy-In”), then the Company shall (A) pay in cash to the Holder the amount, if any, by which (x)

the Holder’s total purchase price (including brokerage commissions, if any) for the shares of Common Stock so purchased exceeds

(y) the amount obtained by multiplying (1) the number of Warrant Shares that the Company was required to deliver to the Holder in connection

with the exercise at issue times (2) the price at which the sell order giving rise to such purchase obligation was executed, and (B)

at the option of the Holder, either reinstate the portion of this Warrant and equivalent number of Warrant Shares for which such exercise

was not honored (in which case such exercise shall be deemed rescinded) or deliver to the Holder the number of shares of Common Stock

that would have been issued had the Company timely complied with its exercise and delivery obligations hereunder. For example, if the

Holder purchases Common Stock having a total purchase price of $11,000 to cover a Buy-In with respect to an attempted exercise of shares

of Common Stock with an aggregate sale price giving rise to such purchase obligation of $10,000, under clause (A) of the immediately

preceding sentence the Company shall be required to pay the Holder $1,000. The Holder shall provide the Company written notice indicating

the amounts payable to the Holder in respect of the Buy-In and, upon request of the Company, evidence of the amount of such loss. Nothing

herein shall limit a Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including, without

limitation, a decree of specific performance and/or injunctive relief with respect to the Company’s failure to timely deliver shares

of Common Stock upon exercise of this Warrant as required pursuant to the terms hereof.

5

v.

No Fractional Shares or Scrip. No fractional shares or scrip representing fractional shares shall be issued upon the exercise

of this Warrant. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company

shall, at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied

by the Exercise Price or round up to the next whole share.

vi.

Charges, Taxes and Expenses. Issuance of Warrant Shares shall be made without charge to the Holder for any issue or transfer tax

or other incidental expense in respect of the issuance of such Warrant Shares, all of which taxes and expenses shall be paid by the Company,

and such Warrant Shares shall be issued in the name of the Holder or in such name or names as may be directed by the Holder; provided,

however, that, in the event that Warrant Shares are to be issued in a name other than the name of the Holder, this Warrant when

surrendered for exercise shall be accompanied by the Assignment Form attached hereto duly executed by the Holder and the Company may

require, as a condition thereto, the payment of a sum sufficient to reimburse it for any transfer tax incidental thereto. The Company

shall pay all Transfer Agent fees required for same-day processing of any Notice of Exercise and all fees to the Depository Trust Company

(or another established clearing corporation performing similar functions) required for same-day electronic delivery of the Warrant Shares.

vii.

Closing of Books. The Company will not close its stockholder books or records in any manner which prevents the timely exercise

of this Warrant, pursuant to the terms hereof.

6

e)

Holder’s Exercise Limitations. The Company shall not effect any exercise of this Warrant, and a Holder shall not have the

right to exercise any portion of this Warrant, pursuant to Section 2 or otherwise, to the extent that after giving effect to such issuance

after exercise as set forth on the applicable Notice of Exercise, the Holder (together with the Holder’s Affiliates, and any other

Persons acting as a group together with the Holder or any of the Holder’s Affiliates (such Persons, “Attribution Parties”)),

would beneficially own in excess of the Beneficial Ownership Limitation (as defined below). For purposes of the foregoing sentence, the

number of shares of Common Stock beneficially owned by the Holder and its Affiliates and Attribution Parties shall include the number

of shares of Common Stock issuable upon exercise of this Warrant with respect to which such determination is being made, but shall exclude

the number of shares of Common Stock which would be issuable upon (i) exercise of the remaining, nonexercised portion of this Warrant

beneficially owned by the Holder or any of its Affiliates or Attribution Parties and (ii) exercise or conversion of the unexercised or

nonconverted portion of any other securities of the Company (including, without limitation, any other Common Stock Equivalents) subject

to a limitation on conversion or exercise analogous to the limitation contained herein beneficially owned by the Holder or any of its

Affiliates or Attribution Parties. Except as set forth in the preceding sentence, for purposes of this Section 2(e), beneficial ownership

shall be calculated in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder, it being

acknowledged by the Holder that the Company is not representing to the Holder that such calculation is in compliance with Section 13(d)

of the Exchange Act and the Holder is solely responsible for any schedules required to be filed in accordance therewith. To the extent

that the limitation contained in this Section 2(e) applies, the determination of whether this Warrant is exercisable (in relation to

other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of this Warrant is exercisable

shall be in the sole discretion of the Holder, and the submission of a Notice of Exercise shall be deemed to be the Holder’s determination

of whether this Warrant is exercisable (in relation to other securities owned by the Holder together with any Affiliates and Attribution

Parties) and of which portion of this Warrant is exercisable, in each case subject to the Beneficial Ownership Limitation. To ensure

compliance with this restriction, Holder will be deemed to represent to the Corporation each time it delivers a Notice of Exercise that

such Notice of Exercise has not violated the restrictions set forth in this paragraph and the Company shall have no obligation to verify

or confirm the accuracy of such determination. In addition, a determination as to any group status as contemplated above shall be determined

in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder. For purposes of this Section

2(e), in determining the number of outstanding shares of Common Stock, a Holder may rely on the number of outstanding shares of Common

Stock as reflected in (A) the Company’s most recent periodic or annual report filed with the Commission, as the case may be, (B)

a more recent public announcement by the Company or (C) a more recent written notice by the Company or the Transfer Agent setting forth

the number of shares of Common Stock outstanding. Upon the written or oral request of a Holder, the Company shall within one Trading

Day confirm orally and in writing to the Holder the number of shares of Common Stock then outstanding. In any case, the number of outstanding

shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company, including

this Warrant, by the Holder or its Affiliates or Attribution Parties since the date as of which such number of outstanding shares of

Common Stock was reported. The “Beneficial Ownership Limitation” shall be [4.99%/9.99%] of the number of shares of

the Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issuable upon exercise of this

Warrant. The Holder, upon notice to the Company, may increase or decrease the Beneficial Ownership Limitation provisions of this Section

2(e), provided that the Beneficial Ownership Limitation in no event exceeds 9.99% of the number of shares of the Common Stock outstanding

immediately after giving effect to the issuance of shares of Common Stock upon exercise of this Warrant held by the Holder and the provisions

of this Section 2(e) shall continue to apply. Any increase in the Beneficial Ownership Limitation will not be effective until the 61st

day after such notice is delivered to the Company. The provisions of this paragraph shall be construed and implemented in a manner otherwise

than in strict conformity with the terms of this Section 2(e) to correct this paragraph (or any portion hereof) which may be defective

or inconsistent with the intended Beneficial Ownership Limitation herein contained or to make changes or supplements necessary or desirable

to properly give effect to such limitation. The limitations contained in this paragraph shall apply to a successor holder of this Warrant.

f)

Issuance Limitations. Notwithstanding anything herein to the contrary, if the Company has not obtained Shareholder Approval, then

the Company may not issue, upon exercise of this Warrant, in whole or in part, a number of shares of Common Stock which, when aggregated

with any shares of Common Stock issued on or after the Issue Date and prior to the exercise of this Warrant, in whole or in part, (i)

in connection with any conversion of Series M 10% Convertible Preferred Stock (the “Preferred Stock”) issued pursuant

to the Purchase Agreement, (ii) in connection with the exercise of any Warrants issued pursuant to the Purchase Agreement and (iii) in

connection with the exercise of any warrants issued to any registered broker-dealer as a fee in connection with the issuance of the Securities

pursuant to the Purchase Agreement, would exceed 360,695 shares of Common Stock (subject to adjustment for forward and reverse stock

splits, recapitalizations and the like) (such number of shares, the “Issuable Maximum”). Holder shall be entitled

to a portion of the Issuable Maximum equal to the quotient obtained by dividing (x) the original Stated Value of Holder’s Preferred

Stock by (y) the aggregate Stated Value of all Preferred Stock issued on the Original Issue Date (as defined in the Certificate of Designation

of Preferences, Rights and Limitations of Preferred Stock of the Company) to all holders of Preferred Stock. In addition, Holder may

allocate its pro-rata portion of the Issuable Maximum among Preferred Stock and Warrants held by it in its sole discretion. Such portion

shall be adjusted upward ratably in the event a Holder no longer holds any Preferred Stock or Warrants and the amount of shares issued

to such Holder pursuant to such Holder’s Preferred Stock and Warrants was less than such Holder’s pro-rata share of the Issuable

Maximum. For avoidance of doubt, unless and until any required Shareholder Approval is obtained and effective, warrants issued to any

registered broker-dealer as a fee in connection with the Securities issued pursuant to the Purchase Agreement as described in clause

(iii) above shall provide that such warrants shall not be allocated any portion of the Issuable Maximum and shall be unexercisable unless

and until such Shareholder Approval is obtained and effective.

7

Section

3. Certain Adjustments.

a)

Stock Dividends and Splits. If the Company, at any time while this Warrant is outstanding: (i) pays a stock dividend or otherwise

makes a distribution or distributions on shares of its Common Stock or any other equity or equity equivalent securities payable in shares

of Common Stock (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Company upon exercise of this

Warrant), (ii) subdivides outstanding shares of Common Stock into a larger number of shares, (iii) combines (including by way of reverse

stock split) outstanding shares of Common Stock into a smaller number of shares, or (iv) issues by reclassification of shares of the

Common Stock any shares of capital stock of the Company, then in each case the Exercise Price shall be multiplied by a fraction of which

the numerator shall be the number of shares of Common Stock (excluding treasury shares, if any) outstanding immediately before such event

and of which the denominator shall be the number of shares of Common Stock outstanding immediately after such event, and the number of

shares issuable upon exercise of this Warrant shall be proportionately adjusted such that the aggregate Exercise Price of this Warrant

shall remain unchanged. Any adjustment made pursuant to this Section 3(a) shall become effective immediately after the record date for

the determination of stockholders entitled to receive such dividend or distribution and shall become effective immediately after the

effective date in the case of a subdivision, combination or re-classification.

b)

Subsequent Equity Sales. If the Company or any Subsidiary thereof, as applicable, at any time while this Warrant is outstanding,

shall sell, enter into an agreement to sell, or grant any option to purchase, or sell or grant any right to reprice, or otherwise dispose

of or issue (or announce any offer, sale, grant or any option to purchase or other disposition), including but not limited, to the exercise

of the Greenshoe Rights pursuant to Section 2.4 of the Purchase Agreement, any Common Stock or Common Stock Equivalents, at an effective

price per share less than the Exercise Price then in effect (such lower price, the “Base Share Price” and such issuances

collectively, a “Dilutive Issuance”) (it being understood and agreed that if the holder of the Common Stock or Common

Stock Equivalents so issued shall at any time, whether by operation of purchase price adjustments, reset provisions, floating conversion,

exercise or exchange prices or otherwise, or due to warrants, options or rights per share which are issued in connection with such issuance,

be entitled to receive shares of Common Stock at an effective price per share that is less than the Exercise Price, such issuance shall

be deemed to have occurred for less than the Exercise Price on such date of the Dilutive Issuance at such effective price), then simultaneously

with the consummation (or, if earlier, the announcement) of each Dilutive Issuance, the Exercise Price shall be reduced and only reduced

to equal the Base Share Price, and the number of Warrant Shares issuable hereunder shall be increased such that the aggregate Exercise

Price payable hereunder, after taking into account the decrease in the Exercise Price, shall be equal to the aggregate Exercise Price

prior to such adjustment. Notwithstanding the foregoing, no adjustments shall be made, paid or issued under this Section 3(b) in respect

of an Exempt Issuance. The Company shall notify the Holder, in writing, no later than the Trading Day following the issuance or deemed

issuance of any Common Stock or Common Stock Equivalents subject to this Section 3(b), indicating therein the applicable issuance price,

or applicable reset price, exchange price, conversion price and other pricing terms (such notice, the “Dilutive Issuance Notice”).

For purposes of clarification, whether or not the Company provides a Dilutive Issuance Notice pursuant to this Section 3(b), upon the

occurrence of any Dilutive Issuance, the Holder is entitled to receive a number of Warrant Shares based upon the Base Share Price regardless

of whether the Holder accurately refers to the Base Share Price in the Notice of Exercise. If the Company enters into a Variable Rate

Transaction, the Company shall be deemed to have issued Common Stock or Common Stock Equivalents at the lowest possible price, conversion

price or exercise price at which such securities may be issued, converted or exercised. If any shares of Common Stock or Common Stock

Equivalents are issued or sold or deemed to have been issued or sold for cash, the consideration received therefor will be deemed to

be the net amount of cash received by the Company therefor. If any shares of Common Stock or Common Stock Equivalents are issued or sold

for consideration other than cash, the amount of such consideration received by the Company will be the fair value of such consideration,

except where such consideration consists of publicly traded securities or Common Stock (including Common Stock transferred from existing

third-party stockholder), in which case the amount of consideration received by the Company will be the volume weighted average price

of such publicly traded securities on the date of receipt of such publicly traded securities. The fair value of any consideration other

than cash or publicly traded securities will be reasonably and in good faith determined jointly by the Company and the Purchasers of

a majority in interest of the Securities then outstanding. If such parties are unable to reach agreement within ten (10) days after the

occurrence of an event requiring valuation (the “Valuation Event”), the fair value of such consideration will be determined

within five (5) Business Days after the tenth (10th) day following the Valuation Event by an independent appraiser selected in good faith

by the Company and reasonably acceptable to the Purchasers of a majority in interest of the Securities then outstanding, the fees and

expenses of which shall be paid by the Company. The determination of such appraiser shall be final and binding upon all parties absent

manifest error.

8

c)

Subsequent Rights Offerings. In addition to any adjustments pursuant to Section 3(a) above, if at any time the Company grants,

issues or sells any Common Stock Equivalents or rights to purchase stock, warrants, securities or other property pro rata to the record

holders of any class of shares of Common Stock (the “Purchase Rights”), then the Holder will be entitled to acquire,

upon the terms applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had

held the number of shares of Common Stock acquirable upon complete exercise of this Warrant (without regard to any limitations on exercise

hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date on which a record is taken for

the grant, issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which the record holders of shares

of Common Stock are to be determined for the grant, issue or sale of such Purchase Rights (provided, however, that, to

the extent that the Holder’s right to participate in any such Purchase Right would result in the Holder exceeding the Beneficial

Ownership Limitation or the Corporation’s issuance of shares in excess of the Issuable Maximum, then the Holder shall not be entitled

to participate in such Purchase Right to such extent (or beneficial ownership of such shares of Common Stock as a result of such Purchase

Right to such extent) and such Purchase Right to such extent shall be held in abeyance for the Holder until such time, if ever, as its

right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation or the Corporation’s issuance of shares

in excess of the Issuable Maximum).

d)

Pro Rata Distributions. During such time as this Warrant is outstanding, if the Company shall declare or make any dividend or

other distribution of its assets (or rights to acquire its assets) to holders of shares of Common Stock, by way of return of capital

or otherwise (including, without limitation, any distribution of cash, stock or other securities, property or options by way of a dividend,

spin off, reclassification, corporate rearrangement, scheme of arrangement or other similar transaction) (a “Distribution”),

at any time after the issuance of this Warrant, then, in each such case, the Holder shall be entitled to participate in such Distribution

to the same extent that the Holder would have participated therein if the Holder had held the number of shares of Common Stock acquirable

upon complete exercise of this Warrant (without regard to any limitations on exercise hereof, including without limitation, the Beneficial

Ownership Limitation) immediately before the date of which a record is taken for such Distribution, or, if no such record is taken, the

date as of which the record holders of shares of Common Stock are to be determined for the participation in such Distribution (provided,

however, that, to the extent that the Holder’s right to participate in any such Distribution would result in the Holder

exceeding the Beneficial Ownership Limitation or the Corporation’s issuance of shares in excess of the Issuable Maximum, then the

Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership of any shares of Common

Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance for the benefit

of the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation

or the Corporation’s issuance of shares in excess of the Issuable Maximum). To the extent that this Warrant has not been partially

or completely exercised at the time of such Distribution, such portion of the Distribution shall be held in abeyance for the benefit

of the Holder until the Holder has exercised this Warrant.

9

e)

Fundamental Transaction. If, at any time while this Warrant is outstanding, (i) the Company, directly or indirectly, in one or

more related transactions effects any merger or consolidation of the Company with or into another Person, (ii) the Company or any Subsidiary,

directly or indirectly, effects any sale, lease, license, assignment, transfer, conveyance or other disposition of all or substantially

all of its assets in one or a series of related transactions, (iii) any, direct or indirect, purchase offer, tender offer or exchange

offer (whether by the Company or another Person) is completed pursuant to which holders of Common Stock are permitted to sell, tender

or exchange their shares for other securities, cash or property and has been accepted by the holders of greater than 50% of the outstanding

Common Stock or greater than 50% of the voting power of the common equity of the Company, (iv) the Company, directly or indirectly, in

one or more related transactions effects any reclassification, reorganization or recapitalization of the Common Stock or any compulsory

share exchange pursuant to which the Common Stock is effectively converted into or exchanged for other securities, cash or property,

or (v) the Company, directly or indirectly, in one or more related transactions consummates a stock or share purchase agreement or other

business combination (including, without limitation, a reorganization, recapitalization, spin-off, merger or scheme of arrangement) with

another Person or group of Persons whereby such other Person or group acquires greater than 50% of the outstanding shares of Common Stock

or greater than 50% of the voting power of the common equity of the Company (each a “Fundamental Transaction”), then,

upon any subsequent exercise of this Warrant, the Holder shall have the right to receive, for each Warrant Share that would have been

issuable upon such exercise immediately prior to the occurrence of such Fundamental Transaction, at the option of the Holder (without

regard to any limitation in Section 2(e) on the exercise of this Warrant), the number of shares of Common Stock of the successor or acquiring

corporation or of the Company, if it is the surviving corporation, and any additional consideration (the “Alternate Consideration”)

receivable as a result of such Fundamental Transaction by a holder of the number of shares of Common Stock for which this Warrant is

exercisable immediately prior to such Fundamental Transaction (without regard to any limitation in Section 2(e) on the exercise of this

Warrant). For purposes of any such exercise, the determination of the Exercise Price shall be appropriately adjusted to apply to such

Alternate Consideration based on the amount of Alternate Consideration issuable in respect of one share of Common Stock in such Fundamental

Transaction, and the Company shall apportion the Exercise Price among the Alternate Consideration in a reasonable manner reflecting the

relative value of any different components of the Alternate Consideration. If holders of Common Stock are given any choice as to the

securities, cash or property to be received in a Fundamental Transaction, then the Holder shall be given the same choice as to the Alternate

Consideration it receives upon any exercise of this Warrant following such Fundamental Transaction. Notwithstanding anything to the contrary,

in the event of a Fundamental Transaction, the Company or any Successor Entity (as defined below) shall, at the Holder’s option,

exercisable at any time concurrently with, or within 30 days after, the consummation of the Fundamental Transaction (or, if later, the

date of the public announcement of the applicable Fundamental Transaction), purchase this Warrant from the Holder by paying to the Holder

an amount of cash equal to the Black Scholes Value (as defined below) of the remaining unexercised portion of this Warrant on the date

of the consummation of such Fundamental Transaction; provided, however, that, if the Fundamental Transaction is not within

the Company’s control, including not approved by the Company’s Board of Directors, the Holder shall only be entitled to receive

from the Company or any Successor Entity the same type or form of consideration (and in the same proportion), at the Black Scholes Value

of the unexercised portion of this Warrant, that is being offered and paid to the holders of Common Stock of the Company in connection

with the Fundamental Transaction, whether that consideration be in the form of cash, stock or any combination thereof, or whether the

holders of Common Stock are given the choice to receive from among alternative forms of consideration in connection with the Fundamental

Transaction; provided, further, that if holders of Common Stock of the Company are not offered or paid any consideration

in such Fundamental Transaction, such holders of Common Stock will be deemed to have received common stock of the Successor Entity (which

Successor Entity may be the Company following such Fundamental Transaction) in such Fundamental Transaction. “Black Scholes

Value” means the value of this Warrant based on the Black-Scholes Option Pricing Model obtained from the “OV” function

on Bloomberg determined as of the day of consummation of the applicable Fundamental Transaction for pricing purposes and reflecting (A)

a risk-free interest rate corresponding to the U.S. Treasury rate for a period equal to the time between the date of the public announcement

of the applicable contemplated Fundamental Transaction and the Termination Date, (B) an expected volatility equal to the 100 day volatility

as obtained from the HVT function on Bloomberg (determined utilizing a 365 day annualization factor) as of the Trading Day immediately

following the public announcement of the applicable contemplated Fundamental Transaction, (C) the underlying price per share used in

such calculation shall be the sum of the price per share being offered in cash, if any, plus the value of any non-cash consideration,

if any, being offered in such Fundamental Transaction, (D) a remaining option time equal to the time between the date of the public announcement

of the applicable contemplated Fundamental Transaction and the Termination Date and (E) a zero cost of borrow. The payment of the Black

Scholes Value will be made by wire transfer of immediately available funds (or such other consideration) within the later of (i) five

Business Days of the Holder’s election and (ii) the date of consummation of the Fundamental Transaction. The Company shall cause

any successor entity in a Fundamental Transaction in which the Company is not the survivor (the “Successor Entity”)

to assume in writing all of the obligations of the Company under this Warrant and the other Transaction Documents in accordance with

the provisions of this Section 3(e) pursuant to written agreements in form and substance reasonably satisfactory to the Holder and approved

by the Holder (without unreasonable delay) prior to such Fundamental Transaction and shall, at the option of the Holder, deliver to the

Holder in exchange for this Warrant a security of the Successor Entity evidenced by a written instrument substantially similar in form

and substance to this Warrant which is exercisable for a corresponding number of shares of capital stock of such Successor Entity (or

its parent entity) equivalent to the shares of Common Stock acquirable and receivable upon exercise of this Warrant (without regard to

any limitations on the exercise of this Warrant) prior to such Fundamental Transaction, and with an exercise price which applies the

exercise price hereunder to such shares of capital stock (but taking into account the relative value of the shares of Common Stock pursuant

to such Fundamental Transaction and the value of such shares of capital stock, such number of shares of capital stock and such exercise

price being for the purpose of protecting the economic value of this Warrant immediately prior to the consummation of such Fundamental

Transaction), and which is reasonably satisfactory in form and substance to the Holder. Upon the occurrence of any such Fundamental Transaction,

the Successor Entity shall be added to the term “Company” under this Warrant (so that from and after the occurrence or consummation

of such Fundamental Transaction, each and every provision of this Warrant and the other Transaction Documents referring to the “Company”

shall refer instead to each of the Company and the Successor Entity or Successor Entities, jointly and severally), and the Successor

Entity or Successor Entities, jointly and severally with the Company, may exercise every right and power of the Company prior thereto

and the Successor Entity or Successor Entities shall assume all of the obligations of the Company prior thereto under this Warrant and

the other Transaction Documents with the same effect as if the Company and such Successor Entity or Successor Entities, jointly and severally,

had been named as the Company herein. For the avoidance of doubt, the Holder shall be entitled to the benefits of the provisions of this

Section 3(e) regardless of (i) whether the Company has sufficient authorized shares of Common Stock for the issuance of Warrant Shares

and/or (ii) whether a Fundamental Transaction occurs prior to the Initial Exercise Date.

10

f)

Calculations. All calculations under this Section 3 shall be made to the nearest cent or the nearest 1/100th of a share, as the

case may be. For purposes of this Section 3, the number of shares of Common Stock deemed to be issued and outstanding as of a given date

shall be the sum of the number of shares of Common Stock (excluding treasury shares, if any) issued and outstanding.

g)

Notice to Holder.

i.

Adjustment to Exercise Price. Whenever the Exercise Price is adjusted pursuant to any provision of this Section 3, the Company

shall promptly deliver to the Holder by email a notice setting forth the Exercise Price after such adjustment and any resulting adjustment

to the number of Warrant Shares and setting forth a brief statement of the facts requiring such adjustment.

ii.

Notice to Allow Exercise by Holder. If (A) the Company shall declare a dividend (or any other distribution in whatever form) on

the Common Stock, (B) the Company shall declare a special nonrecurring cash dividend on or a redemption of the Common Stock, (C) the

Company shall authorize the granting to all holders of the Common Stock rights or warrants to subscribe for or purchase any shares of

capital stock of any class or of any rights, (D) the approval of any stockholders of the Company shall be required in connection with

any reclassification of the Common Stock, any consolidation or merger to which the Company (or any of its Subsidiaries) is a party, any

sale or transfer of all or substantially all of its assets, or any compulsory share exchange whereby the Common Stock is converted into

other securities, cash or property, or (E) the Company shall authorize the voluntary or involuntary dissolution, liquidation or winding

up of the affairs of the Company, then, in each case, the Company shall cause to be delivered by email to the Holder at its last email

address as it shall appear upon the Warrant Register of the Company, at least 20 calendar days prior to the applicable record or effective

date hereinafter specified, a notice stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution,

redemption, rights or warrants, or if a record is not to be taken, the date as of which the holders of the Common Stock of record to

be entitled to such dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on which such reclassification,

consolidation, merger, sale, transfer or share exchange is expected to become effective or close, and the date as of which it is expected

that holders of the Common Stock of record shall be entitled to exchange their shares of the Common Stock for securities, cash or other

property deliverable upon such reclassification, consolidation, merger, sale, transfer or share exchange; provided that the failure to

deliver such notice or any defect therein or in the delivery thereof shall not affect the validity of the corporate action required to

be specified in such notice. To the extent that any notice provided in this Warrant constitutes, or contains, material, non-public information

regarding the Company or any of the Subsidiaries, the Company shall simultaneously file such notice with the Commission pursuant to a

Current Report on Form 8-K. The Holder shall remain entitled to exercise this Warrant during the period commencing on the date of such

notice to the effective date of the event triggering such notice except as may otherwise be expressly set forth herein.

11

Section

4. Transfer of Warrant.

a)

Transferability. Subject to compliance with any applicable securities laws and the conditions set forth in Section 4(d) hereof

and to the provisions of Section 4.1 of the Purchase Agreement, this Warrant and all rights hereunder (including, without limitation,

any registration rights) are transferable, in whole or in part, upon surrender of this Warrant at the principal office of the Company

or its designated agent, together with a written assignment of this Warrant substantially in the form attached hereto duly executed by

the Holder or its agent or attorney and funds sufficient to pay any transfer taxes payable upon the making of such transfer. Upon such

surrender and, if required, such payment, the Company shall execute and deliver a new Warrant or Warrants in the name of the assignee

or assignees, as applicable, and in the denomination or denominations specified in such instrument of assignment, and shall issue to

the assignor a new Warrant evidencing the portion of this Warrant not so assigned, and this Warrant shall promptly be cancelled. Notwithstanding

anything herein to the contrary, the Holder shall not be required to physically surrender this Warrant to the Company unless the Holder

has assigned this Warrant in full, in which case, the Holder shall surrender this Warrant to the Company within three (3) Trading Days

of the date on which the Holder delivers an assignment form to the Company assigning this Warrant in full. This Warrant, if properly

assigned in accordance herewith, may be exercised by a new holder for the purchase of Warrant Shares without having a new Warrant issued.

b)

New Warrants. This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of

the Company, together with a written notice specifying the names and denominations in which new Warrants are to be issued, signed by

the Holder or its agent or attorney. Subject to compliance with Section 4(a), as to any transfer which may be involved in such division

or combination, the Company shall execute and deliver a new Warrant or Warrants in exchange for this Warrant or the Warrants to be divided

or combined in accordance with such notice. All Warrants issued on transfers or exchanges shall be dated the initial issuance date of

this Warrant and shall be identical with this Warrant except as to the number of Warrant Shares issuable pursuant thereto.

c)

Warrant Register. The Company shall register this Warrant, upon records to be maintained by the Company for that purpose (the

“Warrant Register”), in the name of the record Holder hereof from time to time. The Company may deem and treat the

registered Holder of this Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder,

and for all other purposes, absent actual notice to the contrary.

d)

Transfer Restrictions. If, at the time of the surrender of this Warrant in connection with any transfer of this Warrant, the transfer

of this Warrant shall not be either (i) registered pursuant to an effective registration statement under the Securities Act and under

applicable state securities or blue sky laws or (ii) eligible for resale without volume or manner-of-sale restrictions or current public

information requirements pursuant to Rule 144, the Company may require, as a condition of allowing such transfer, that the Holder or

transferee of this Warrant, as the case may be, comply with the provisions of Section 5.7 of the Purchase Agreement.

12

e)

Representation by the Holder. The Holder, by the acceptance hereof, represents and warrants that it is acquiring this Warrant

and, upon any exercise hereof, will acquire the Warrant Shares issuable upon such exercise, for its own account and not with a view to

or for distributing or reselling such Warrant Shares or any part thereof in violation of the Securities Act or any applicable state securities

law, except pursuant to sales registered or exempted under the Securities Act.

Section

5. Miscellaneous.

a)

No Rights as Stockholder Until Exercise; No Settlement in Cash. This Warrant does not entitle the Holder to any voting rights,

dividends or other rights as a stockholder of the Company prior to the exercise hereof as set forth in Section 2(d)(i), except as expressly

set forth in Section 3. Without limiting any rights of a Holder to receive Warrant Shares on a “cashless exercise” pursuant

to Section 2(c) or to receive cash payments pursuant to Section 2(d)(i) and Section 2(d)(iv) herein, in no event shall the Company be

required to net cash settle an exercise of this Warrant.

b)

Loss, Theft, Destruction or Mutilation of Warrant. The Company covenants that upon receipt by the Company of evidence reasonably

satisfactory to it of the loss, theft, destruction or mutilation of this Warrant or any stock certificate relating to the Warrant Shares,

and in case of loss, theft or destruction, of indemnity or security reasonably satisfactory to it (which, in the case of this Warrant,

shall not include the posting of any bond), and upon surrender and cancellation of such Warrant or stock certificate, if mutilated, the

Company will make and deliver a new Warrant or stock certificate of like tenor and dated as of such cancellation, in lieu of such Warrant

or stock certificate.

c)

Saturdays, Sundays, Holidays, etc. If the last or appointed day for the taking of any action or the expiration of any right required

or granted herein shall not be a Business Day, then such action may be taken or such right may be exercised on the next succeeding Business

Day.

d)

Authorized Shares.

The

Company covenants that, during the period this Warrant is outstanding, it will reserve from its authorized and unissued Common Stock

an amount of shares at least equal to the Required Minimum (as defined in the Purchase Agreement). The Company further covenants that

its issuance of this Warrant shall constitute full authority to its officers who are charged with the duty of issuing the necessary Warrant

Shares upon the exercise of the purchase rights under this Warrant. The Company will take all such reasonable action as may be necessary

to assure that such Warrant Shares may be issued as provided herein without violation of any applicable law or regulation, or of any

requirements of the Trading Market upon which the Common Stock may be listed. The Company covenants that all Warrant Shares which may

be issued upon the exercise of the purchase rights represented by this Warrant will, upon exercise of the purchase rights represented

by this Warrant and payment for such Warrant Shares in accordance herewith, be duly authorized, validly issued, fully paid and nonassessable

and free from all taxes, liens and charges created by the Company in respect of the issue thereof (other than taxes in respect of any

transfer occurring contemporaneously with such issue).

13

Except

and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending

its certificate of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale

of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant,

but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary

or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the generality of the

foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor upon such exercise

immediately prior to such increase in par value, (ii) take all such action as may be necessary or appropriate in order that the Company

may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant and (iii) use commercially

reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction thereof,

as may be, necessary to enable the Company to perform its obligations under this Warrant.

Before

taking any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the

Exercise Price, the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from

any public regulatory body or bodies having jurisdiction thereof.

e)

Jurisdiction. All questions concerning the construction, validity, enforcement and interpretation of this Warrant shall be determined

in accordance with the provisions of the Purchase Agreement.

f)

Restrictions. The Holder acknowledges that the Warrant Shares acquired upon the exercise of this Warrant, if not registered, and

the Holder does not utilize cashless exercise, will have restrictions upon resale imposed by state and federal securities laws.

g)

Nonwaiver and Expenses. No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall

operate as a waiver of such right or otherwise prejudice the Holder’s rights, powers or remedies. Without limiting any other provision

of this Warrant or the Purchase Agreement, if the Company willfully and knowingly fails to comply with any provision of this Warrant,

which results in any material damages to the Holder, the Company shall pay to the Holder such amounts as shall be sufficient to cover

any costs and expenses including, but not limited to, reasonable attorneys’ fees, including those of appellate proceedings, incurred

by the Holder in collecting any amounts due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.

14

h)

Notices. Any notice, request or other document required or permitted to be given or delivered to the Holder by the Company shall

be delivered in accordance with the notice provisions of the Purchase Agreement.

i)

Limitation of Liability. No provision hereof, in the absence of any affirmative action by the Holder to exercise this Warrant

to purchase Warrant Shares, and no enumeration herein of the rights or privileges of the Holder, shall give rise to any liability of

the Holder for the purchase price of any Common Stock or as a stockholder of the Company, whether such liability is asserted by the Company

or by creditors of the Company.

j)

Remedies. The Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will

be entitled to specific performance of its rights under this Warrant. The Company agrees that monetary damages would not be adequate

compensation for any loss incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive and not to

assert the defense in any action for specific performance that a remedy at law would be adequate.

k)

Successors and Assigns. Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall

inure to the benefit of and be binding upon the successors and permitted assigns of the Company and the successors and permitted assigns

of Holder. The provisions of this Warrant are intended to be for the benefit of any Holder from time to time of this Warrant and shall

be enforceable by the Holder or holder of Warrant Shares.

l)

Amendment. This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company and

the Holder.

m)

Severability. Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid

under applicable law, but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall

be ineffective to the extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining

provisions of this Warrant.

n)

Headings. The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed

a part of this Warrant.

********************

(Signature

Page Follows)

15

IN

WITNESS WHEREOF, the Company has caused this Warrant to be executed by its officer thereunto duly authorized as of the date first above

indicated.

GT

Biopharma, Inc.

By:

Name:

Alan

Urban

Title:

Chief

Financial Officer

16

NOTICE

OF EXERCISE

To:

GT Biopharma, Inc.

(1)

The undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant (only

if exercised in full), and tenders herewith payment of the exercise price in full, together with all applicable transfer taxes, if any.

(2)

Payment shall take the form of (check applicable box):

[

] in lawful money of the United States; or

[

] if permitted the cancellation of such number of Warrant Shares as is necessary, in accordance with the formula set forth in subsection

2(c), to exercise this Warrant with respect to the maximum number of Warrant Shares purchasable pursuant to the cashless exercise procedure

set forth in subsection 2(c).

(3)

Please issue said Warrant Shares in the name of the undersigned or in such other name as is specified below:

_______________________________

The

Warrant Shares shall be delivered to the following DWAC Account Number:

_______________________________

_______________________________

_______________________________

(4)

Accredited Investor. The undersigned is an “accredited investor” as defined in Regulation D promulgated under the Securities

Act of 1933, as amended.

[SIGNATURE

OF HOLDER]

Name

of Investing Entity: ________________________________________________________________________

Signature

of Authorized Signatory of Investing Entity: _________________________________________________

Name

of Authorized Signatory: ___________________________________________________________________

Title

of Authorized Signatory: ____________________________________________________________________

Date:

________________________________________________________________________________________

EXHIBIT

B

ASSIGNMENT

FORM

(To

assign the foregoing Warrant, execute this form and supply required information. Do not use this form to purchase shares.)

FOR

VALUE RECEIVED, the foregoing Warrant and all rights evidenced thereby are hereby assigned to

Name:

(Please

Print)

Address:

(Please

Print)

Phone

Number:

Email

Address:

Dated:

_______________ __, ______

Holder’s

Signature:___________________

Holder’s

Address:___________________

EX-4.2

EX-4.2

Filename: ex4-2.htm · Sequence: 4

Exhibit

4.2

NEITHER

THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION

OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED

(THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT

UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS

OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS. THIS SECURITY AND THE SECURITIES ISSUABLE UPON EXERCISE

OF THIS SECURITY MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN SECURED BY SUCH SECURITIES.

COMMON

STOCK VESTING WARRANTS

GT

Biopharma, Inc.

Warrant

No.: _______

Warrant Shares: _______

Issue Date: September 14, 2026

THIS

COMMON STOCK VESTING WARRANT (this “Warrant”) certifies that, for value received, _____________ or its assigns (the

“Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set

forth, at any time on or after September 14, 2026 (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New

York City time) on the five-year anniversary of the date that the applicable Warrant Shares vest hereunder (each, a “Termination

Date”) but not thereafter, to subscribe for and purchase from GT Biopharma, Inc., a Delaware corporation (the “Company”),

up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock; provided, however,

the exercisability of this Warrant shall vest ratably from time to time in proportion to the Holder’s (or its permitted assigns)

exercise of such Holder’s Greenshoe Rights pursuant to Section 2.4 of the Purchase Agreement compared with all Greenshoe Securities

issuable to the Holder pursuant to the Greenshoe Right pursuant to Section 2.4 of the Purchase Agreement (“Vesting Schedule”).

By way of example, if the Holder exercises all of its Greenshoe Rights pursuant to Section 2.4 of the Purchase Agreement, all Warrant

Shares hereunder may be exercised by the Holder and if the Holder exercises half of its Greenshoe Rights, only half of the Warrant Shares

hereunder may be exercised by the Holder until such time that the Holder exercises additional Greenshoe Rights pursuant to Section 2.4

of the Purchase Agreement. Notwithstanding anything herein to the contrary, the purchase price of one share of Common Stock under this

Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

Section

1. Definitions. Capitalized terms used and not otherwise defined herein shall have the meanings set forth in that certain

Securities Purchase Agreement (the “Purchase Agreement”), dated September 14, 2026, among the Company and the purchasers

signatory thereto.

1

Section

2. Exercise.

a)

Exercise of Warrant. Exercise of the purchase rights represented by this Warrant may be made, in whole or in part, at any time

or times on or after the Initial Exercise Date in accordance with the Vesting Schedule and on or before the applicable Termination Date

by delivery to the Company of a duly executed PDF copy submitted by e-mail (or e-mail attachment) of the Notice of Exercise in the form

annexed hereto (the “Notice of Exercise”). Within the earlier of (i) one (1) Trading Day and (ii) the number of Trading

Days comprising the Standard Settlement Period (as defined in Section 2(d)(i) herein) following the date of exercise as aforesaid, the

Holder shall deliver the aggregate Exercise Price for the shares specified in the applicable Notice of Exercise by wire transfer or cashier’s

check drawn on a United States bank unless the cashless exercise procedure specified in Section 2(c) below is specified in the applicable

Notice of Exercise. No ink-original Notice of Exercise shall be required, nor shall any medallion guarantee (or other type of guarantee

or notarization) of any Notice of Exercise be required. Notwithstanding anything herein to the contrary, the Holder shall not be required

to physically surrender this Warrant to the Company until the Holder has purchased all of the Warrant Shares available hereunder and

this Warrant has been exercised in full, in which case, the Holder shall surrender this Warrant to the Company for cancellation within

three (3) Trading Days of the date on which the final Notice of Exercise is delivered to the Company. Partial exercises of this Warrant

resulting in purchases of a portion of the total number of Warrant Shares available hereunder shall have the effect of lowering the outstanding

number of Warrant Shares purchasable hereunder in an amount equal to the applicable number of Warrant Shares purchased. The Holder and

the Company shall maintain records showing the number of Warrant Shares purchased and the date of such purchases. The Company shall deliver

any objection to any Notice of Exercise within one (1) Trading Day of receipt of such notice. The Holder and any assignee, by acceptance

of this Warrant, acknowledge and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the

Warrant Shares hereunder, the number of Warrant Shares available for purchase hereunder at any given time may be less than the amount

stated on the face hereof.

b)

Exercise Price. The exercise price per share of Common Stock under this Warrant shall be $6.10, subject to adjustment hereunder

(the “Exercise Price”).

c)

Cashless Exercise. If at the time of exercise hereof there is no effective registration statement registering, or the prospectus

contained therein is not available for the resale of the Warrant Shares by the Holder, then this Warrant may also be exercised, in whole

or in part, at such time by means of a “cashless exercise” in which the Holder shall be entitled to receive a number of Warrant

Shares equal to the quotient obtained by dividing [(A-B) (X)] by (A), where:

(A)

=

as

applicable: (i) the VWAP on the Trading Day immediately preceding the date of the applicable Notice of Exercise if such Notice of Exercise

is (1) delivered pursuant to Section 2(a) hereof on a day that is not a Trading Day or (2) delivered pursuant to Section 2(a) hereof

on a Trading Day prior to the opening of “regular trading hours” (as defined in Rule 600(b) of Regulation NMS promulgated

under the federal securities laws) on such Trading Day, (ii) the highest Bid Price of the Common Stock on the principal Trading Market

as reported by Bloomberg L.P. (“Bloomberg”) within two (2) hours of the time of the Holder’s delivery of the

Notice of Exercise pursuant to Section 2(a) hereof if such Notice of Exercise is delivered during “regular trading hours,”

or with two (2) hours after the close of “regular trading hours,” on a Trading Day or (iii) the VWAP on the date of the applicable

Notice of Exercise if the date of such Notice of Exercise is a Trading Day and such Notice of Exercise is delivered pursuant to Section

2(a) hereof after two (2) hours following the close of “regular trading hours” on such Trading Day;

(B)

=

the

Exercise Price of this Warrant, as adjusted hereunder; and

(X)

=

the

number of Warrant Shares that would be issuable upon exercise of this Warrant in accordance with the terms of this Warrant if such

exercise were by means of a cash exercise rather than a cashless exercise.

2

If

Warrant Shares are issued in such a cashless exercise, the parties acknowledge and agree that in accordance with Section 3(a)(9) of the

Securities Act, the holding period of the Warrant Shares being issued may be tacked on to the holding period of this Warrant. The Company

agrees not to take any position contrary to this Section 2(c).

“Bid

Price” means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock

is then listed or quoted on a Trading Market, the bid price of the Common Stock for the time in question (or the nearest preceding date)

on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg (based on a Trading Day from 9:30 a.m.

(New York City time) to 4:02 p.m. (New York City time)), (b) if OTCQB or OTCQX is not a Trading Market, the volume weighted average price

of the Common Stock for such date (or the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then

listed or quoted for trading on OTCQB or OTCQX and if prices for the Common Stock are then reported on The Pink Open Market (or a similar

organization or agency succeeding to its functions of reporting prices), the most recent bid price per share of the Common Stock so reported,

or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser selected in good

faith by the Company and reasonably acceptable to the Purchasers of a majority in interest of the Securities then outstanding, the fees

and expenses of which shall be paid by the Company.

“VWAP”

means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed

or quoted on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date)

on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg (based on a Trading Day from 9:30 a.m.

(New York City time) to 4:02 p.m. (New York City time)), (b) if the OTCQB Venture Market (“OTCQB”) or the OTCQX Best

Market (“OTCQX”) is not a Trading Market, the volume weighted average price of the Common Stock for such date (or

the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then listed or quoted for trading on OTCQB

or OTCQX and if prices for the Common Stock are then reported on the Pink Open Market (“Pink Market”) operated by

the OTC Markets, Inc. (or a similar organization or agency succeeding to its functions of reporting prices), the most recent bid price

per share of the Common Stock so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined

by an independent appraiser selected in good faith by the Company and reasonably acceptable to the Purchasers of a majority in interest

of the Securities then outstanding, the fees and expenses of which shall be paid by the Company.

Notwithstanding

anything herein to the contrary, on the applicable Termination Date, this Warrant shall be automatically exercised via cashless exercise

pursuant to this Section 2(c).

Notwithstanding

anything herein to the contrary, in the event that any cashless exercise pursuant to this paragraph would otherwise cause the Holder

to exceed the Beneficial Ownership Limitation, the Company shall only issue such number of Warrant Shares to the Holder that would not

cause the Holder to exceed the maximum number of Warrant Shares permitted pursuant to the Beneficial Ownership Limitation, as directed

by the Holder, with the balance to be held in abeyance until notice from the Holder that the balance (or portion thereof) may be issued

in compliance with such Beneficial Ownership Limitation.

3

d)

Mechanics of Exercise.

i.

Delivery of Warrant Shares Upon Exercise. The Company shall cause the Warrant Shares purchased hereunder to be transmitted by

the Transfer Agent to the Holder by crediting the account of the Holder’s or its designee’s balance account with The Depository

Trust Company through its Deposit or Withdrawal at Custodian system (“DWAC”) if the Company is then a participant

in such system and either (A) there is an effective registration statement permitting the issuance of the Warrant Shares to or resale

of the Warrant Shares by Holder or (B) the Warrant Shares are eligible for resale by the Holder without volume or manner-of-sale limitations

pursuant to Rule 144 (assuming cashless exercise of this Warrant), and otherwise by physical delivery of a certificate, registered in

the Company’s share register in the name of the Holder or its designee, for the number of Warrant Shares to which the Holder is

entitled pursuant to such exercise to the address specified by the Holder in the Notice of Exercise by the date that is the earlier of

(i) one (1) Trading Day after the delivery to the Company of the Notice of Exercise and (ii) the number of Trading Days comprising the

Standard Settlement Period after the delivery to the Company of the Notice of Exercise (such date, the “Warrant Share Delivery

Date”); provided, however, that the aggregate Exercise Price has been delivered to the Company by the Warrant Share Delivery

Date. Upon delivery of the Notice of Exercise, the Holder shall be deemed for all corporate purposes to have become the holder of record

of the Warrant Shares with respect to which this Warrant has been exercised, irrespective of the date of delivery of the Warrant Shares,

provided that payment of the aggregate Exercise Price (other than in the case of a cashless exercise) is received within the earlier

of (i) one (1) Trading Day and (ii) the number of Trading Days comprising the Standard Settlement Period following delivery of the Notice

of Exercise. If the Holder duly exercises this Warrant pursuant to Section 2(a) hereof and the Company fails for any reason to deliver

to the Holder the Warrant Shares subject to a Notice of Exercise by the Warrant Share Delivery Date, the Company shall pay to the Holder,

in cash, as liquidated damages and not as a penalty, for each $1,000 of Warrant Shares subject to such exercise (based on the VWAP of

the Common Stock on the date of the applicable Notice of Exercise), $10 per Trading Day (increasing to $20 per Trading Day on the third

Trading Day after the Warrant Share Delivery Date) for each Trading Day after such Warrant Share Delivery Date until such Warrant Shares

are delivered or Holder rescinds such exercise. The Company agrees to maintain a transfer agent that is a participant in the FAST program

so long as this Warrant remains outstanding and exercisable. As used herein, “Standard Settlement Period” means the

standard settlement period, expressed in a number of Trading Days, on the Company’s primary Trading Market with respect to the

Common Stock as in effect on the date of delivery of the Notice of Exercise.

ii.

Delivery of New Warrants Upon Exercise. If this Warrant shall have been exercised in part, the Company shall, at the request of

a Holder and upon surrender of this Warrant certificate, at the time of delivery of the Warrant Shares, deliver to the Holder a new Warrant

evidencing the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant, which new Warrant shall in

all other respects be identical with this Warrant.

iii.

Rescission Rights. If the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares pursuant to Section

2(d)(i) by the Warrant Share Delivery Date, then the Holder will have the right to rescind such exercise.

4

iv.

Compensation for Buy-In on Failure to Timely Deliver Warrant Shares Upon Exercise. In addition to any other rights available to

the Holder, if the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares in accordance with the provisions

of Section 2(d)(i) above pursuant to an exercise on or before the Warrant Share Delivery Date, and if after such date the Holder is required

by its broker to purchase (in an open market transaction or otherwise) or the Holder’s brokerage firm otherwise purchases, shares

of Common Stock to deliver in satisfaction of a sale by the Holder of the Warrant Shares which the Holder anticipated receiving upon

such exercise (a “Buy-In”), then the Company shall (A) pay in cash to the Holder the amount, if any, by which (x)

the Holder’s total purchase price (including brokerage commissions, if any) for the shares of Common Stock so purchased exceeds

(y) the amount obtained by multiplying (1) the number of Warrant Shares that the Company was required to deliver to the Holder in connection

with the exercise at issue times (2) the price at which the sell order giving rise to such purchase obligation was executed, and (B)

at the option of the Holder, either reinstate the portion of this Warrant and equivalent number of Warrant Shares for which such exercise

was not honored (in which case such exercise shall be deemed rescinded) or deliver to the Holder the number of shares of Common Stock

that would have been issued had the Company timely complied with its exercise and delivery obligations hereunder. For example, if the

Holder purchases Common Stock having a total purchase price of $11,000 to cover a Buy-In with respect to an attempted exercise of shares

of Common Stock with an aggregate sale price giving rise to such purchase obligation of $10,000, under clause (A) of the immediately

preceding sentence the Company shall be required to pay the Holder $1,000. The Holder shall provide the Company written notice indicating

the amounts payable to the Holder in respect of the Buy-In and, upon request of the Company, evidence of the amount of such loss. Nothing

herein shall limit a Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including, without

limitation, a decree of specific performance and/or injunctive relief with respect to the Company’s failure to timely deliver shares

of Common Stock upon exercise of this Warrant as required pursuant to the terms hereof.

v.

No Fractional Shares or Scrip. No fractional shares or scrip representing fractional shares shall be issued upon the exercise

of this Warrant. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company

shall, at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied

by the Exercise Price or round up to the next whole share.

vi.

Charges, Taxes and Expenses. Issuance of Warrant Shares shall be made without charge to the Holder for any issue or transfer tax

or other incidental expense in respect of the issuance of such Warrant Shares, all of which taxes and expenses shall be paid by the Company,

and such Warrant Shares shall be issued in the name of the Holder or in such name or names as may be directed by the Holder; provided,

however, that, in the event that Warrant Shares are to be issued in a name other than the name of the Holder, this Warrant when

surrendered for exercise shall be accompanied by the Assignment Form attached hereto duly executed by the Holder and the Company may

require, as a condition thereto, the payment of a sum sufficient to reimburse it for any transfer tax incidental thereto. The Company

shall pay all Transfer Agent fees required for same-day processing of any Notice of Exercise and all fees to the Depository Trust Company

(or another established clearing corporation performing similar functions) required for same-day electronic delivery of the Warrant Shares.

vii.

Closing of Books. The Company will not close its stockholder books or records in any manner which prevents the timely exercise

of this Warrant, pursuant to the terms hereof.

5

e)

Holder’s Exercise Limitations. The Company shall not effect any exercise of this Warrant, and a Holder shall not have the

right to exercise any portion of this Warrant, pursuant to Section 2 or otherwise, to the extent that after giving effect to such issuance

after exercise as set forth on the applicable Notice of Exercise, the Holder (together with the Holder’s Affiliates, and any other

Persons acting as a group together with the Holder or any of the Holder’s Affiliates (such Persons, “Attribution Parties”)),

would beneficially own in excess of the Beneficial Ownership Limitation (as defined below). For purposes of the foregoing sentence, the

number of shares of Common Stock beneficially owned by the Holder and its Affiliates and Attribution Parties shall include the number

of shares of Common Stock issuable upon exercise of this Warrant with respect to which such determination is being made, but shall exclude

the number of shares of Common Stock which would be issuable upon (i) exercise of the remaining, nonexercised portion of this Warrant

beneficially owned by the Holder or any of its Affiliates or Attribution Parties and (ii) exercise or conversion of the unexercised or

nonconverted portion of any other securities of the Company (including, without limitation, any other Common Stock Equivalents) subject

to a limitation on conversion or exercise analogous to the limitation contained herein beneficially owned by the Holder or any of its

Affiliates or Attribution Parties. Except as set forth in the preceding sentence, for purposes of this Section 2(e), beneficial ownership

shall be calculated in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder, it being

acknowledged by the Holder that the Company is not representing to the Holder that such calculation is in compliance with Section 13(d)

of the Exchange Act and the Holder is solely responsible for any schedules required to be filed in accordance therewith. To the extent

that the limitation contained in this Section 2(e) applies, the determination of whether this Warrant is exercisable (in relation to

other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of this Warrant is exercisable

shall be in the sole discretion of the Holder, and the submission of a Notice of Exercise shall be deemed to be the Holder’s determination

of whether this Warrant is exercisable (in relation to other securities owned by the Holder together with any Affiliates and Attribution

Parties) and of which portion of this Warrant is exercisable, in each case subject to the Beneficial Ownership Limitation. To ensure

compliance with this restriction, Holder will be deemed to represent to the Corporation each time it delivers a Notice of Exercise that

such Notice of Exercise has not violated the restrictions set forth in this paragraph and the Company shall have no obligation to verify

or confirm the accuracy of such determination. In addition, a determination as to any group status as contemplated above shall be determined

in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder. For purposes of this Section

2(e), in determining the number of outstanding shares of Common Stock, a Holder may rely on the number of outstanding shares of Common

Stock as reflected in (A) the Company’s most recent periodic or annual report filed with the Commission, as the case may be, (B)

a more recent public announcement by the Company or (C) a more recent written notice by the Company or the Transfer Agent setting forth

the number of shares of Common Stock outstanding. Upon the written or oral request of a Holder, the Company shall within one Trading

Day confirm orally and in writing to the Holder the number of shares of Common Stock then outstanding. In any case, the number of outstanding

shares of Common Stock shall be determined after giving effect to the conversion or exercise of securities of the Company, including

this Warrant, by the Holder or its Affiliates or Attribution Parties since the date as of which such number of outstanding shares of

Common Stock was reported. The “Beneficial Ownership Limitation” shall be [4.99%/9.99%] of the number of shares of

the Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issuable upon exercise of this

Warrant. The Holder, upon notice to the Company, may increase or decrease the Beneficial Ownership Limitation provisions of this Section

2(e), provided that the Beneficial Ownership Limitation in no event exceeds 9.99% of the number of shares of the Common Stock outstanding

immediately after giving effect to the issuance of shares of Common Stock upon exercise of this Warrant held by the Holder and the provisions

of this Section 2(e) shall continue to apply. Any increase in the Beneficial Ownership Limitation will not be effective until the 61st

day after such notice is delivered to the Company. The provisions of this paragraph shall be construed and implemented in a manner otherwise

than in strict conformity with the terms of this Section 2(e) to correct this paragraph (or any portion hereof) which may be defective

or inconsistent with the intended Beneficial Ownership Limitation herein contained or to make changes or supplements necessary or desirable

to properly give effect to such limitation. The limitations contained in this paragraph shall apply to a successor holder of this Warrant.

f)

Issuance Limitations. Notwithstanding anything herein to the contrary, if the Company has not obtained Shareholder Approval, then

the Company may not issue, upon exercise of this Warrant, in whole or in part, a number of shares of Common Stock which, when aggregated

with any shares of Common Stock issued on or after the Issue Date and prior to the exercise of this Warrant, in whole or in part, (i)

in connection with any conversion of Series L 10% Convertible Preferred Stock (the “Preferred Stock”) issued pursuant

to the Purchase Agreement, (ii) in connection with the exercise of any Warrants issued pursuant to the Purchase Agreement and (iii) in

connection with the exercise of any warrants issued to any registered broker-dealer as a fee in connection with the issuance of the Securities

pursuant to the Purchase Agreement, would exceed 360,695 shares of Common Stock (subject to adjustment for forward and reverse stock

splits, recapitalizations and the like) (such number of shares, the “Issuable Maximum”). Holder shall be entitled

to a portion of the Issuable Maximum equal to the quotient obtained by dividing (x) the original Stated Value of Holder’s Preferred

Stock by (y) the aggregate Stated Value of all Preferred Stock issued on the Original Issue Date (as defined in the Certificate of Designation

of Preferences, Rights and Limitations of Preferred Stock of the Company) to all holders of Preferred Stock. In addition, Holder may

allocate its pro-rata portion of the Issuable Maximum among Preferred Stock and Warrants held by it in its sole discretion. Such portion

shall be adjusted upward ratably in the event a Holder no longer holds any Preferred Stock or Warrants and the amount of shares issued

to such Holder pursuant to such Holder’s Preferred Stock and Warrants was less than such Holder’s pro-rata share of the Issuable

Maximum. For avoidance of doubt, unless and until any required Shareholder Approval is obtained and effective, warrants issued to any

registered broker-dealer as a fee in connection with the Securities issued pursuant to the Purchase Agreement as described in clause

(iii) above shall provide that such warrants shall not be allocated any portion of the Issuable Maximum and shall be unexercisable unless

and until such Shareholder Approval is obtained and effective.

6

Section

3. Certain Adjustments.

a)

Stock Dividends and Splits. If the Company, at any time while this Warrant is outstanding: (i) pays a stock dividend or otherwise

makes a distribution or distributions on shares of its Common Stock or any other equity or equity equivalent securities payable in shares

of Common Stock (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Company upon exercise of this

Warrant), (ii) subdivides outstanding shares of Common Stock into a larger number of shares, (iii) combines (including by way of reverse

stock split) outstanding shares of Common Stock into a smaller number of shares, or (iv) issues by reclassification of shares of the

Common Stock any shares of capital stock of the Company, then in each case the Exercise Price shall be multiplied by a fraction of which

the numerator shall be the number of shares of Common Stock (excluding treasury shares, if any) outstanding immediately before such event

and of which the denominator shall be the number of shares of Common Stock outstanding immediately after such event, and the number of

shares issuable upon exercise of this Warrant shall be proportionately adjusted such that the aggregate Exercise Price of this Warrant

shall remain unchanged. Any adjustment made pursuant to this Section 3(a) shall become effective immediately after the record date for

the determination of stockholders entitled to receive such dividend or distribution and shall become effective immediately after the

effective date in the case of a subdivision, combination or re-classification.

b)

Subsequent Equity Sales. If the Company or any Subsidiary thereof, as applicable, at any time while this Warrant is outstanding,

shall sell, enter into an agreement to sell, or grant any option to purchase, or sell or grant any right to reprice, or otherwise dispose

of or issue (or announce any offer, sale, grant or any option to purchase or other disposition) including but not limited, to the exercise

of the Greenshoe Rights pursuant to Section 2.4 of the Purchase Agreement, any Common Stock or Common Stock Equivalents, at an effective

price per share less than the Exercise Price then in effect (such lower price, the “Base Share Price” and such issuances

collectively, a “Dilutive Issuance”) (it being understood and agreed that if the holder of the Common Stock or Common

Stock Equivalents so issued shall at any time, whether by operation of purchase price adjustments, reset provisions, floating conversion,

exercise or exchange prices or otherwise, or due to warrants, options or rights per share which are issued in connection with such issuance,

be entitled to receive shares of Common Stock at an effective price per share that is less than the Exercise Price, such issuance shall

be deemed to have occurred for less than the Exercise Price on such date of the Dilutive Issuance at such effective price), then simultaneously

with the consummation (or, if earlier, the announcement) of each Dilutive Issuance, the Exercise Price shall be reduced and only reduced

to equal the Base Share Price and the number of Warrant Shares issuable hereunder shall be increased such that the aggregate Exercise

Price payable hereunder, after taking into account the decrease in the Exercise Price, shall be equal to the aggregate Exercise Price

prior to such adjustment. Notwithstanding the foregoing, no adjustments shall be made, paid or issued under this Section 3(b) in respect

of an Exempt Issuance. The Company shall notify the Holder, in writing, no later than the Trading Day following the issuance or deemed

issuance of any Common Stock or Common Stock Equivalents subject to this Section 3(b), indicating therein the applicable issuance price,

or applicable reset price, exchange price, conversion price and other pricing terms (such notice, the “Dilutive Issuance Notice”).

For purposes of clarification, whether or not the Company provides a Dilutive Issuance Notice pursuant to this Section 3(b), upon the

occurrence of any Dilutive Issuance, the Holder is entitled to receive a number of Warrant Shares based upon the Base Share Price regardless

of whether the Holder accurately refers to the Base Share Price in the Notice of Exercise. If the Company enters into a Variable Rate

Transaction, the Company shall be deemed to have issued Common Stock or Common Stock Equivalents at the lowest possible price, conversion

price or exercise price at which such securities may be issued, converted or exercised. If any shares of Common Stock or Common Stock

Equivalents are issued or sold or deemed to have been issued or sold for cash, the consideration received therefor will be deemed to

be the net amount of cash received by the Company therefor. If any shares of Common Stock or Common Stock Equivalents are issued or sold

for consideration other than cash, the amount of such consideration received by the Company will be the fair value of such consideration,

except where such consideration consists of publicly traded securities or Common Stock (including Common Stock transferred from existing

third-party stockholder), in which case the amount of consideration received by the Company will be the volume weighted average price

of such publicly traded securities on the date of receipt of such publicly traded securities. The fair value of any consideration other

than cash or publicly traded securities will be reasonably and in good faith determined jointly by the Company and the Purchasers of

a majority in interest of the Securities then outstanding. If such parties are unable to reach agreement within ten (10) days after the

occurrence of an event requiring valuation (the “Valuation Event”), the fair value of such consideration will be determined

within five (5) Business Days after the tenth (10th) day following the Valuation Event by an independent appraiser selected in good faith

by the Company and reasonably acceptable to the Purchasers of a majority in interest of the Securities then outstanding, the fees and

expenses of which shall be paid by the Company. The determination of such appraiser shall be final and binding upon all parties absent

manifest error.

7

c)

Subsequent Rights Offerings. In addition to any adjustments pursuant to Section 3(a) above, if at any time the Company grants,

issues or sells any Common Stock Equivalents or rights to purchase stock, warrants, securities or other property pro rata to the record

holders of any class of shares of Common Stock (the “Purchase Rights”), then the Holder will be entitled to acquire,

upon the terms applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had

held the number of shares of Common Stock acquirable upon complete exercise of this Warrant (without regard to any limitations on exercise

hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date on which a record is taken for

the grant, issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which the record holders of shares

of Common Stock are to be determined for the grant, issue or sale of such Purchase Rights (provided, however, that, to

the extent that the Holder’s right to participate in any such Purchase Right would result in the Holder exceeding the Beneficial

Ownership Limitation or the Corporation’s issuance of shares in excess of the Issuable Maximum, then the Holder shall not be entitled

to participate in such Purchase Right to such extent (or beneficial ownership of such shares of Common Stock as a result of such Purchase

Right to such extent) and such Purchase Right to such extent shall be held in abeyance for the Holder until such time, if ever, as its

right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation or the Corporation’s issuance of shares

in excess of the Issuable Maximum).

d)

Pro Rata Distributions. During such time as this Warrant is outstanding, if the Company shall declare or make any dividend or

other distribution of its assets (or rights to acquire its assets) to holders of shares of Common Stock, by way of return of capital

or otherwise (including, without limitation, any distribution of cash, stock or other securities, property or options by way of a dividend,

spin off, reclassification, corporate rearrangement, scheme of arrangement or other similar transaction) (a “Distribution”),

at any time after the issuance of this Warrant, then, in each such case, the Holder shall be entitled to participate in such Distribution

to the same extent that the Holder would have participated therein if the Holder had held the number of shares of Common Stock acquirable

upon complete exercise of this Warrant (without regard to any limitations on exercise hereof, including without limitation, the Beneficial

Ownership Limitation) immediately before the date of which a record is taken for such Distribution, or, if no such record is taken, the

date as of which the record holders of shares of Common Stock are to be determined for the participation in such Distribution (provided,

however, that, to the extent that the Holder’s right to participate in any such Distribution would result in the Holder

exceeding the Beneficial Ownership Limitation or the Corporation’s issuance of shares in excess of the Issuable Maximum, then the

Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership of any shares of Common

Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance for the benefit

of the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation

or the Corporation’s issuance of shares in excess of the Issuable Maximum). To the extent that this Warrant has not been partially

or completely exercised at the time of such Distribution, such portion of the Distribution shall be held in abeyance for the benefit

of the Holder until the Holder has exercised this Warrant.

8

e)

Fundamental Transaction. If, at any time while this Warrant is outstanding, (i) the Company, directly or indirectly, in one or

more related transactions effects any merger or consolidation of the Company with or into another Person, (ii) the Company or any Subsidiary,

directly or indirectly, effects any sale, lease, license, assignment, transfer, conveyance or other disposition of all or substantially

all of its assets in one or a series of related transactions, (iii) any, direct or indirect, purchase offer, tender offer or exchange

offer (whether by the Company or another Person) is completed pursuant to which holders of Common Stock are permitted to sell, tender

or exchange their shares for other securities, cash or property and has been accepted by the holders of greater than 50% of the outstanding

Common Stock or greater than 50% of the voting power of the common equity of the Company, (iv) the Company, directly or indirectly, in

one or more related transactions effects any reclassification, reorganization or recapitalization of the Common Stock or any compulsory

share exchange pursuant to which the Common Stock is effectively converted into or exchanged for other securities, cash or property,

or (v) the Company, directly or indirectly, in one or more related transactions consummates a stock or share purchase agreement or other

business combination (including, without limitation, a reorganization, recapitalization, spin-off, merger or scheme of arrangement) with

another Person or group of Persons whereby such other Person or group acquires greater than 50% of the outstanding shares of Common Stock

or greater than 50% of the voting power of the common equity of the Company (each a “Fundamental Transaction”), then,

upon any subsequent exercise of this Warrant, the Holder shall have the right to receive, for each Warrant Share that would have been

issuable upon such exercise immediately prior to the occurrence of such Fundamental Transaction, at the option of the Holder (without

regard to any limitation in Section 2(e) on the exercise of this Warrant), the number of shares of Common Stock of the successor or acquiring

corporation or of the Company, if it is the surviving corporation, and any additional consideration (the “Alternate Consideration”)

receivable as a result of such Fundamental Transaction by a holder of the number of shares of Common Stock for which this Warrant is

exercisable immediately prior to such Fundamental Transaction (without regard to any limitation in Section 2(e) on the exercise of this

Warrant). For purposes of any such exercise, the determination of the Exercise Price shall be appropriately adjusted to apply to such

Alternate Consideration based on the amount of Alternate Consideration issuable in respect of one share of Common Stock in such Fundamental

Transaction, and the Company shall apportion the Exercise Price among the Alternate Consideration in a reasonable manner reflecting the

relative value of any different components of the Alternate Consideration. If holders of Common Stock are given any choice as to the

securities, cash or property to be received in a Fundamental Transaction, then the Holder shall be given the same choice as to the Alternate

Consideration it receives upon any exercise of this Warrant following such Fundamental Transaction. Notwithstanding anything to the contrary,

in the event of a Fundamental Transaction, the Company or any Successor Entity (as defined below) shall, at the Holder’s option,

exercisable at any time concurrently with, or within 30 days after, the consummation of the Fundamental Transaction (or, if later, the

date of the public announcement of the applicable Fundamental Transaction), purchase this Warrant from the Holder by paying to the Holder

an amount of cash equal to the Black Scholes Value (as defined below) of the remaining unexercised portion of this Warrant on the date

of the consummation of such Fundamental Transaction; provided, however, that, if the Fundamental Transaction is not within

the Company’s control, including not approved by the Company’s Board of Directors, the Holder shall only be entitled to receive

from the Company or any Successor Entity the same type or form of consideration (and in the same proportion), at the Black Scholes Value

of the unexercised portion of this Warrant, that is being offered and paid to the holders of Common Stock of the Company in connection

with the Fundamental Transaction, whether that consideration be in the form of cash, stock or any combination thereof, or whether the

holders of Common Stock are given the choice to receive from among alternative forms of consideration in connection with the Fundamental

Transaction; provided, further, that if holders of Common Stock of the Company are not offered or paid any consideration

in such Fundamental Transaction, such holders of Common Stock will be deemed to have received common stock of the Successor Entity (which

Successor Entity may be the Company following such Fundamental Transaction) in such Fundamental Transaction. “Black Scholes

Value” means the value of this Warrant based on the Black-Scholes Option Pricing Model obtained from the “OV” function

on Bloomberg determined as of the day of consummation of the applicable Fundamental Transaction for pricing purposes and reflecting (A)

a risk-free interest rate corresponding to the U.S. Treasury rate for a period equal to the time between the date of the public announcement

of the applicable contemplated Fundamental Transaction and the applicable Termination Date, (B) an expected volatility equal to the 100

day volatility as obtained from the HVT function on Bloomberg (determined utilizing a 365 day annualization factor) as of the Trading

Day immediately following the public announcement of the applicable contemplated Fundamental Transaction, (C) the underlying price per

share used in such calculation shall be the sum of the price per share being offered in cash, if any, plus the value of any non-cash

consideration, if any, being offered in such Fundamental Transaction, (D) a remaining option time equal to the time between the date

of the public announcement of the applicable contemplated Fundamental Transaction and the applicable Termination Date and (E) a zero

cost of borrow. The payment of the Black Scholes Value will be made by wire transfer of immediately available funds (or such other consideration)

within the later of (i) five Business Days of the Holder’s election and (ii) the date of consummation of the Fundamental Transaction.

The Company shall cause any successor entity in a Fundamental Transaction in which the Company is not the survivor (the “Successor

Entity”) to assume in writing all of the obligations of the Company under this Warrant and the other Transaction Documents

in accordance with the provisions of this Section 3(e) pursuant to written agreements in form and substance reasonably satisfactory to

the Holder and approved by the Holder (without unreasonable delay) prior to such Fundamental Transaction and shall, at the option of

the Holder, deliver to the Holder in exchange for this Warrant a security of the Successor Entity evidenced by a written instrument substantially

similar in form and substance to this Warrant which is exercisable for a corresponding number of shares of capital stock of such Successor

Entity (or its parent entity) equivalent to the shares of Common Stock acquirable and receivable upon exercise of this Warrant (without

regard to any limitations on the exercise of this Warrant) prior to such Fundamental Transaction, and with an exercise price which applies

the exercise price hereunder to such shares of capital stock (but taking into account the relative value of the shares of Common Stock

pursuant to such Fundamental Transaction and the value of such shares of capital stock, such number of shares of capital stock and such

exercise price being for the purpose of protecting the economic value of this Warrant immediately prior to the consummation of such Fundamental

Transaction), and which is reasonably satisfactory in form and substance to the Holder. Upon the occurrence of any such Fundamental Transaction,

the Successor Entity shall be added to the term “Company” under this Warrant (so that from and after the occurrence or consummation

of such Fundamental Transaction, each and every provision of this Warrant and the other Transaction Documents referring to the “Company”

shall refer instead to each of the Company and the Successor Entity or Successor Entities, jointly and severally), and the Successor

Entity or Successor Entities, jointly and severally with the Company, may exercise every right and power of the Company prior thereto

and the Successor Entity or Successor Entities shall assume all of the obligations of the Company prior thereto under this Warrant and

the other Transaction Documents with the same effect as if the Company and such Successor Entity or Successor Entities, jointly and severally,

had been named as the Company herein. For the avoidance of doubt, the Holder shall be entitled to the benefits of the provisions of this

Section 3(e) regardless of (i) whether the Company has sufficient authorized shares of Common Stock for the issuance of Warrant Shares

and/or (ii) whether a Fundamental Transaction occurs prior to the Initial Exercise Date.

9

f)

Calculations. All calculations under this Section 3 shall be made to the nearest cent or the nearest 1/100th of a share, as the

case may be. For purposes of this Section 3, the number of shares of Common Stock deemed to be issued and outstanding as of a given date

shall be the sum of the number of shares of Common Stock (excluding treasury shares, if any) issued and outstanding.

g)

Notice to Holder.

i.

Adjustment to Exercise Price. Whenever the Exercise Price is adjusted pursuant to any provision of this Section 3, the Company

shall promptly deliver to the Holder by email a notice setting forth the Exercise Price after such adjustment and any resulting adjustment

to the number of Warrant Shares and setting forth a brief statement of the facts requiring such adjustment.

ii.

Notice to Allow Exercise by Holder. If (A) the Company shall declare a dividend (or any other distribution in whatever form) on

the Common Stock, (B) the Company shall declare a special nonrecurring cash dividend on or a redemption of the Common Stock, (C) the

Company shall authorize the granting to all holders of the Common Stock rights or warrants to subscribe for or purchase any shares of

capital stock of any class or of any rights, (D) the approval of any stockholders of the Company shall be required in connection with

any reclassification of the Common Stock, any consolidation or merger to which the Company (or any of its Subsidiaries) is a party, any

sale or transfer of all or substantially all of its assets, or any compulsory share exchange whereby the Common Stock is converted into

other securities, cash or property, or (E) the Company shall authorize the voluntary or involuntary dissolution, liquidation or winding

up of the affairs of the Company, then, in each case, the Company shall cause to be delivered by email to the Holder at its last email

address as it shall appear upon the Warrant Register of the Company, at least 20 calendar days prior to the applicable record or effective

date hereinafter specified, a notice stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution,

redemption, rights or warrants, or if a record is not to be taken, the date as of which the holders of the Common Stock of record to

be entitled to such dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on which such reclassification,

consolidation, merger, sale, transfer or share exchange is expected to become effective or close, and the date as of which it is expected

that holders of the Common Stock of record shall be entitled to exchange their shares of the Common Stock for securities, cash or other

property deliverable upon such reclassification, consolidation, merger, sale, transfer or share exchange; provided that the failure to

deliver such notice or any defect therein or in the delivery thereof shall not affect the validity of the corporate action required to

be specified in such notice. To the extent that any notice provided in this Warrant constitutes, or contains, material, non-public information

regarding the Company or any of the Subsidiaries, the Company shall simultaneously file such notice with the Commission pursuant to a

Current Report on Form 8-K. The Holder shall remain entitled to exercise this Warrant during the period commencing on the date of such

notice to the effective date of the event triggering such notice except as may otherwise be expressly set forth herein.

Section

4. Transfer of Warrant.

a)

Transferability. Subject to compliance with any applicable securities laws and the conditions set forth in Section 4(d) hereof

and to the provisions of Section 4.1 of the Purchase Agreement, this Warrant and all rights hereunder (including, without limitation,

any registration rights) are transferable, in whole or in part, upon surrender of this Warrant at the principal office of the Company

or its designated agent, together with a written assignment of this Warrant substantially in the form attached hereto duly executed by

the Holder or its agent or attorney and funds sufficient to pay any transfer taxes payable upon the making of such transfer. Upon such

surrender and, if required, such payment, the Company shall execute and deliver a new Warrant or Warrants in the name of the assignee

or assignees, as applicable, and in the denomination or denominations specified in such instrument of assignment, and shall issue to

the assignor a new Warrant evidencing the portion of this Warrant not so assigned, and this Warrant shall promptly be cancelled. Notwithstanding

anything herein to the contrary, the Holder shall not be required to physically surrender this Warrant to the Company unless the Holder

has assigned this Warrant in full, in which case, the Holder shall surrender this Warrant to the Company within three (3) Trading Days

of the date on which the Holder delivers an assignment form to the Company assigning this Warrant in full. This Warrant, if properly

assigned in accordance herewith, may be exercised by a new holder for the purchase of Warrant Shares without having a new Warrant issued.

10

b)

New Warrants. This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of

the Company, together with a written notice specifying the names and denominations in which new Warrants are to be issued, signed by

the Holder or its agent or attorney. Subject to compliance with Section 4(a), as to any transfer which may be involved in such division

or combination, the Company shall execute and deliver a new Warrant or Warrants in exchange for this Warrant or the Warrants to be divided

or combined in accordance with such notice. All Warrants issued on transfers or exchanges shall be dated the initial issuance date of

this Warrant and shall be identical with this Warrant except as to the number of Warrant Shares issuable pursuant thereto.

c)

Warrant Register. The Company shall register this Warrant, upon records to be maintained by the Company for that purpose (the

“Warrant Register”), in the name of the record Holder hereof from time to time. The Company may deem and treat the

registered Holder of this Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder,

and for all other purposes, absent actual notice to the contrary.

d)

Transfer Restrictions. If, at the time of the surrender of this Warrant in connection with any transfer of this Warrant, the transfer

of this Warrant shall not be either (i) registered pursuant to an effective registration statement under the Securities Act and under

applicable state securities or blue sky laws or (ii) eligible for resale without volume or manner-of-sale restrictions or current public

information requirements pursuant to Rule 144, the Company may require, as a condition of allowing such transfer, that the Holder or

transferee of this Warrant, as the case may be, comply with the provisions of Section 5.7 of the Purchase Agreement.

e)

Representation by the Holder. The Holder, by the acceptance hereof, represents and warrants that it is acquiring this Warrant

and, upon any exercise hereof, will acquire the Warrant Shares issuable upon such exercise, for its own account and not with a view to

or for distributing or reselling such Warrant Shares or any part thereof in violation of the Securities Act or any applicable state securities

law, except pursuant to sales registered or exempted under the Securities Act.

Section

5. Miscellaneous.

a)

No Rights as Stockholder Until Exercise; No Settlement in Cash. This Warrant does not entitle the Holder to any voting rights,

dividends or other rights as a stockholder of the Company prior to the exercise hereof as set forth in Section 2(d)(i), except as expressly

set forth in Section 3. Without limiting any rights of a Holder to receive Warrant Shares on a “cashless exercise” pursuant

to Section 2(c) or to receive cash payments pursuant to Section 2(d)(i) and Section 2(d)(iv) herein, in no event shall the Company be

required to net cash settle an exercise of this Warrant.

b)

Loss, Theft, Destruction or Mutilation of Warrant. The Company covenants that upon receipt by the Company of evidence reasonably

satisfactory to it of the loss, theft, destruction or mutilation of this Warrant or any stock certificate relating to the Warrant Shares,

and in case of loss, theft or destruction, of indemnity or security reasonably satisfactory to it (which, in the case of this Warrant,

shall not include the posting of any bond), and upon surrender and cancellation of such Warrant or stock certificate, if mutilated, the

Company will make and deliver a new Warrant or stock certificate of like tenor and dated as of such cancellation, in lieu of such Warrant

or stock certificate.

c)

Saturdays, Sundays, Holidays, etc. If the last or appointed day for the taking of any action or the expiration of any right required

or granted herein shall not be a Business Day, then such action may be taken or such right may be exercised on the next succeeding Business

Day.

d)

Authorized Shares.

The

Company covenants that, during the period this Warrant is outstanding, it will reserve from its authorized and unissued Common Stock

an amount of shares at least equal to the Required Minimum (as defined in the Purchase Agreement). The Company further covenants that

its issuance of this Warrant shall constitute full authority to its officers who are charged with the duty of issuing the necessary Warrant

Shares upon the exercise of the purchase rights under this Warrant. The Company will take all such reasonable action as may be necessary

to assure that such Warrant Shares may be issued as provided herein without violation of any applicable law or regulation, or of any

requirements of the Trading Market upon which the Common Stock may be listed. The Company covenants that all Warrant Shares which may

be issued upon the exercise of the purchase rights represented by this Warrant will, upon exercise of the purchase rights represented

by this Warrant and payment for such Warrant Shares in accordance herewith, be duly authorized, validly issued, fully paid and nonassessable

and free from all taxes, liens and charges created by the Company in respect of the issue thereof (other than taxes in respect of any

transfer occurring contemporaneously with such issue).

11

Except

and to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending

its certificate of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale

of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant,

but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary

or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the generality of the

foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable therefor upon such exercise

immediately prior to such increase in par value, (ii) take all such action as may be necessary or appropriate in order that the Company

may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant and (iii) use commercially

reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction thereof,

as may be, necessary to enable the Company to perform its obligations under this Warrant.

Before

taking any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the

Exercise Price, the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from

any public regulatory body or bodies having jurisdiction thereof.

e)

Jurisdiction. All questions concerning the construction, validity, enforcement and interpretation of this Warrant shall be determined

in accordance with the provisions of the Purchase Agreement.

f)

Restrictions. The Holder acknowledges that the Warrant Shares acquired upon the exercise of this Warrant, if not registered, and

the Holder does not utilize cashless exercise, will have restrictions upon resale imposed by state and federal securities laws.

g)

Nonwaiver and Expenses. No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall

operate as a waiver of such right or otherwise prejudice the Holder’s rights, powers or remedies. Without limiting any other provision

of this Warrant or the Purchase Agreement, if the Company willfully and knowingly fails to comply with any provision of this Warrant,

which results in any material damages to the Holder, the Company shall pay to the Holder such amounts as shall be sufficient to cover

any costs and expenses including, but not limited to, reasonable attorneys’ fees, including those of appellate proceedings, incurred

by the Holder in collecting any amounts due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.

h)

Notices. Any notice, request or other document required or permitted to be given or delivered to the Holder by the Company shall

be delivered in accordance with the notice provisions of the Purchase Agreement.

i)

Limitation of Liability. No provision hereof, in the absence of any affirmative action by the Holder to exercise this Warrant

to purchase Warrant Shares, and no enumeration herein of the rights or privileges of the Holder, shall give rise to any liability of

the Holder for the purchase price of any Common Stock or as a stockholder of the Company, whether such liability is asserted by the Company

or by creditors of the Company.

j)

Remedies. The Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will

be entitled to specific performance of its rights under this Warrant. The Company agrees that monetary damages would not be adequate

compensation for any loss incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive and not to

assert the defense in any action for specific performance that a remedy at law would be adequate.

k)

Successors and Assigns. Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall

inure to the benefit of and be binding upon the successors and permitted assigns of the Company and the successors and permitted assigns

of Holder. The provisions of this Warrant are intended to be for the benefit of any Holder from time to time of this Warrant and shall

be enforceable by the Holder or holder of Warrant Shares.

l)

Amendment. This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company and

the Holder.

m)

Severability. Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid

under applicable law, but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall

be ineffective to the extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining

provisions of this Warrant.

n)

Headings. The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed

a part of this Warrant.

********************

(Signature

Page Follows)

12

IN

WITNESS WHEREOF, the Company has caused this Warrant to be executed by its officer thereunto duly authorized as of the date first above

indicated.

GT Biopharma,

Inc.

By:

Name:

Alan Urban

Title:

Chief Financial Officer

13

NOTICE

OF EXERCISE

To:

GT Biopharma, Inc.

(1)

The undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant (only

if exercised in full), and tenders herewith payment of the exercise price in full, together with all applicable transfer taxes, if any.

(2)

Payment shall take the form of (check applicable box):

[  ] in lawful money of the United States; or

[  ] if permitted the cancellation of such number of Warrant Shares as is necessary, in accordance with the formula set forth in subsection

2(c), to exercise this Warrant with respect to the maximum number of Warrant Shares purchasable pursuant to the cashless exercise procedure

set forth in subsection 2(c).

(3)

Please issue said Warrant Shares in the name of the undersigned or in such other name as is specified below:

The

Warrant Shares shall be delivered to the following DWAC Account Number:

(4)

Accredited Investor. The undersigned is an “accredited investor” as defined in Regulation D promulgated under the Securities

Act of 1933, as amended.

[SIGNATURE

OF HOLDER]

Name

of Investing Entity: ________________________________________________________________________

Signature

of Authorized Signatory of Investing Entity: __________________________________________________

Name

of Authorized Signatory: ____________________________________________________________________

Title

of Authorized Signatory: _____________________________________________________________________

Date:

________________________________________________________________________________________

EXHIBIT

B

ASSIGNMENT

FORM

(To

assign the foregoing Warrant, execute this form and supply required information. Do not use this form to purchase shares.)

FOR

VALUE RECEIVED, the foregoing Warrant and all rights evidenced thereby are hereby assigned to

Name:

(Please

Print)

Address:

(Please

Print)

Phone

Number:

Email

Address:

Dated:

_______________ __, ______

Holder’s

Signature:________________________________

Holder’s

Address:_________________________________

EX-10.1

EX-10.1

Filename: ex10-1.htm · Sequence: 5

Exhibit

10.1

SECURITIES

PURCHASE AGREEMENT

This

Securities Purchase Agreement (this “Agreement”) is dated as of September 14, 2026, between GT Biopharma, Inc., a

Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including

its successors and assigns, a “Purchaser” and collectively, the “Purchasers”).

WHEREAS,

subject to the terms and conditions set forth in this Agreement and pursuant to Section 4(a)(2) of the Securities Act (as defined below),

and Rule 506 promulgated thereunder, the Company desires to issue and sell to each Purchaser, and each Purchaser, severally and not jointly,

desires to purchase from the Company, securities of the Company as more fully described in this Agreement.

NOW,

THEREFORE, IN CONSIDERATION of the mutual covenants contained in this Agreement, and for other good and valuable consideration the receipt

and adequacy of which are hereby acknowledged, the Company and each Purchaser agree as follows:

ARTICLE

I.

DEFINITIONS

1.1

Definitions. In addition to the terms defined elsewhere in this Agreement: (a) capitalized terms that are not otherwise defined

herein have the meanings given to such terms in the Certificate of Designation (as defined herein), and (b) the following terms have

the meanings set forth in this Section 1.1:

“Acquiring

Person” shall have the meaning ascribed to such term in Section 4.7.

“Action”

shall have the meaning ascribed to such term in Section 3.1(j).

“Affiliate”

means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control

with a Person, as such terms are used in and construed under Rule 405 under the Securities Act.

“Board

of Directors” means the board of directors of the Company.

“Business

Day” means any day other than Saturday, Sunday or other day on which commercial banks in The City of New York are authorized

or required by law to remain closed; provided, however, for clarification, commercial banks shall not be deemed to be authorized

or required by law to remain closed due to “stay at home”, “shelter-in-place”, “non-essential employee”

or any other similar orders or restrictions or the closure of any physical branch locations at the direction of any governmental authority

so long as the electronic funds transfer systems (including for wire transfers) of commercial banks in The City of New York are generally

open for use by customers on such day.

“Certificate

of Designation” means the Certificate of Designation to be filed prior to the Closing by the Company with the Secretary of

State of Delaware, in the form of Exhibit A attached hereto.

“Closing”

means the closing of the purchase and sale of the Securities pursuant to Section 2.1.

“Closing

Date” means the Trading Day on which all of the Transaction Documents have been executed and delivered by the applicable parties

thereto, and all conditions precedent to (i) the Purchasers’ obligations to pay the Subscription Amount and (ii) the Company’s

obligations to deliver the Securities, in each case, have been satisfied or waived.

“Commission”

means the United States Securities and Exchange Commission.

“Common

Stock” means the common stock of the Company, par value $0.001 per share, and any other class of securities into which such

securities may hereafter be reclassified or changed.

“Common

Stock Equivalents” means any securities of the Company or the Subsidiaries which would entitle the holder thereof to acquire

at any time Common Stock, including, without limitation, any debt, preferred stock, right, option, warrant or other instrument that is

at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock.

“Common

Stock Warrants” means the Common Stock Warrants delivered to the Purchasers at the Closing in accordance with Section 2.2(a)

hereof, which Common Stock Warrants shall be exercisable immediately and have a term of exercise equal to five (5) years, in the form

of Exhibit C attached hereto and with an exercise price equal to $6.10, subject to adjustment therein.

“Common

Stock Warrant Shares” means the shares of Common Stock issuable upon exercise of the Common Stock Warrants.

“Company

Counsel” means Baker & Hostetler, LLP, with offices located at 1900 Avenue of the Stars, Suite 2700, Los Angeles, CA 90067.

“Conversion

Price” shall have the meaning ascribed to such term in the Certificate of Designation.

“Conversion

Shares” shall have the meaning ascribed to such term in the Certificate of Designation.

“Disclosure

Schedules” shall have the meaning ascribed to such term in Section 3.1.

“Disclosure

Time” means, (i) if this Agreement is signed on a day that is not a Trading Day or after 9:00 a.m. (New York City time) and

before midnight (New York City time) on any Trading Day, 9:01 a.m. (New York City time) on the Trading Day immediately following the

date hereof, and (ii) if this Agreement is signed between midnight (New York City time) and 9:00 a.m. (New York City time) on any Trading

Day, no later than 9:01 a.m. (New York City time) on the date hereof.

“Effective

Date” means the earliest of the date that (a) the initial Registration Statement has been declared effective by the Commission,

(b) all of the Underlying Shares have been sold pursuant to Rule 144 or may be sold pursuant to Rule 144 without the requirement for

the Company to be in compliance with the current public information required under Rule 144 and without volume or manner-of-sale restrictions,

(c) immediately follows the one year anniversary of the Closing Date provided that a holder of Underlying Shares is not an Affiliate

of the Company, or (d) all of the Underlying Shares may be sold pursuant to an exemption from registration under Section 4(a)(1) of the

Securities Act without volume or manner-of-sale restrictions and Company Counsel has delivered to such holders a standing written unqualified

opinion that resales may then be made by such holders of the Underlying Shares pursuant to such exemption which opinion shall be in form

and substance reasonably acceptable to such holders.

“Evaluation

Date” shall have the meaning ascribed to such term in Section 3.1(s).

“Exchange

Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder.

2

“Exempt

Issuance” means the issuance of (a) shares of Common Stock or options to employees, officers or directors of the Company pursuant

to any stock or option plan duly adopted for such purpose, by a majority of the non-employee members of the Board of Directors or a majority

of the members of a committee of non-employee directors established for such purpose for services rendered to the Company, (b) securities

upon the exercise or exchange of or conversion of any Securities issued hereunder and/or other securities exercisable or exchangeable

for or convertible into shares of Common Stock issued and outstanding on the date of this Agreement, provided that such securities have

not been amended since the date of this Agreement to increase the number of such securities or to decrease the exercise price, exchange

price or conversion price of such securities (other than in connection with stock splits or combinations) or to extend the term of such

securities or (c) securities issued pursuant to acquisitions or strategic transactions approved by a majority of the disinterested directors

of the Company, provided that such securities are issued as “restricted securities” (as defined in Rule 144) and carry no

registration rights that require or permit the filing of any registration statement in connection therewith during the prohibition period

in Section 4.13(a) herein, and provided that any such issuance shall only be to a Person (or to the equityholders of a Person) which

is, itself or through its subsidiaries, an operating company or an owner of an asset in a business synergistic with the business of the

Company and shall provide to the Company additional benefits in addition to the investment of funds, but shall not include a transaction

in which the Company is issuing securities primarily for the purpose of raising capital or to an entity whose primary business is investing

in securities. Notwithstanding anything herein to the contrary, in no event shall the exercise of the Greenshoe Rights pursuant to Section

2.4 be deemed an Exempt Issuance hereunder.

“FCPA”

means the Foreign Corrupt Practices Act of 1977, as amended.

“FDA”

shall have the meaning ascribed to such term in Section 3.1(ll).

“FDCA”

shall have the meaning ascribed to such term in Section 3.1(ll).

“Five

Narrow Lane Counsel” means Haynes and Boone, LLP, with offices located at 30 Rockefeller Plaza; 22nd Floor; New York, NY 10112,

representing Five Narrow Lane, L.P. and no other Purchasers.

“Floor

Price” shall have the meaning set forth in Section 6(b) of the Certificate of Designation.

“GAAP”

shall have the meaning ascribed to such term in Section 3.1(h).

“Indebtedness”

shall have the meaning ascribed to such term in Section 3.1(bb).

“Intellectual

Property Rights” shall have the meaning ascribed to such term in Section 3.1(p).

“Legend

Removal Date” shall have the meaning ascribed to such term in Section 4.1(c).

“Liens”

means a lien, charge, pledge, security interest, encumbrance, right of first refusal, preemptive right or other restriction.

3

“Lock-Up

Agreement” means the Lock-Up Agreement, dated as of the date hereof, by and among the Company and the directors, officers,

and 10% and greater stockholders of the Company, in the form of Exhibit E attached hereto.

“Material

Adverse Effect” shall have the meaning assigned to such term in Section 3.1(b).

“Material

Permits” shall have the meaning ascribed to such term in Section 3.1(n).

“Maximum

Rate” shall have the meaning ascribed to such term in Section 5.17.

“Participation

Maximum” shall have the meaning ascribed to such term in Section 4.12(a).

“Person”

means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability

company, joint stock company, government (or an agency or subdivision thereof) or other entity of any kind.

“Pharmaceutical

Product” shall have the meaning ascribed to such term in Section 3.1(ll).

“Preferred

Stock” means the up to 41,777.778 shares of the Company’s Series M 10% Convertible Preferred Stock issued hereunder having

the rights, preferences and privileges set forth in the Certificate of Designation, in the form of Exhibit A hereto and with a

conversion price equal to $6.10 per share, subject to adjustment therein.

“Pro

Rata Portion” shall have the meaning ascribed to such term in Section 4.12(e).

“Proceeding”

means an action, claim, suit, investigation or proceeding (including, without limitation, an informal investigation or partial proceeding,

such as a deposition), whether commenced or threatened.

“Public

Information Failure” shall have the meaning ascribed to such term in Section 4.3(b).

“Public

Information Failure Payments” shall have the meaning ascribed to such term in Section 4.3(b).

“Purchaser

Party” shall have the meaning ascribed to such term in Section 4.10.

4

“Registration

Rights Agreement” means the Registration Rights Agreement, dated on or about the date hereof, among the Company and the Purchasers,

in the form of Exhibit B attached hereto.

“Registration

Statement” means a registration statement meeting the requirements set forth in the Registration Rights Agreement and covering

the resale of the Underlying Shares by each Purchaser as provided for in the Registration Rights Agreement.

“Required

Approvals” shall have the meaning ascribed to such term in Section 3.1(e).

“Required

Minimum” means, as of any date, the maximum aggregate number of shares of Common Stock then issued or potentially issuable

in the future pursuant to the Transaction Documents, including any Underlying Shares issuable upon exercise in full of all Warrants or

conversion in full of all shares of Preferred Stock, ignoring any conversion or exercise limits set forth therein and assuming a Conversion

Price and Exercise Price, as applicable, equal to the Floor Price; provided, however, that until Shareholder Approval is obtained, the

Required Minimum shall in no event exceed 19.99% of the issued and outstanding Common Stock on the Closing Date.

“Rule

144” means Rule 144 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted

from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose and effect

as such Rule.

“Rule

424” means Rule 424 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted

from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose and effect

as such Rule.

“SEC

Reports” shall have the meaning ascribed to such term in Section 3.1(h).

“Securities”

means the Preferred Stock, the Warrants, the Warrant Shares and the Underlying Shares.

“Securities

Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.

“Shareholder

Approval” means (i) such approval as may be required by the applicable rules and regulations of the Nasdaq Stock Market (or

any successor entity) from the shareholders of the Company with respect to the transactions contemplated by the Transaction Documents,

including the issuance of all of the Underlying Shares and the Dividend Conversion Shares (as defined in the Certificate of Designation)

in excess of 19.99% of the issued and outstanding Common Stock on the Closing Date, and (ii) such approval as may be required to effect

any necessary increase in authorized shares of Common Stock if the number of Underlying Shares is greater than the number of authorized

shares of Common Stock.

5

“Short

Sales” means all “short sales” as defined in Rule 200 of Regulation SHO under the Exchange Act (but shall not be

deemed to include locating and/or borrowing shares of Common Stock).

“Stated

Value” means $1,000 per share of Preferred Stock.

“Subscription

Amount” means, as to each Purchaser, the aggregate amount to be paid for the Preferred Stock purchased hereunder as of the

Closing Date as specified below such Purchaser’s name on the signature page of this Agreement and next to the heading “Subscription

Amount,” in United States dollars and in immediately available funds.

“Subsequent

Financing” shall have the meaning ascribed to such term in Section 4.12(a).

“Subsequent

Financing Notice” shall have the meaning ascribed to such term in Section 4.12(b).

“Subsidiary”

means any subsidiary of the Company as set forth on Schedule 3.1(a) and shall, where applicable, also include any direct or indirect

subsidiary of the Company formed or acquired after the date hereof.

“Trading

Day” means a day on which the principal Trading Market is open for trading.

“Trading

Market” means any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date

in question: the NYSE American, the Nasdaq Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market, the New York Stock

Exchange, the Pink Open Market, OTCQB or the OTCQX (or any successors to any of the foregoing).

“Trading

Price” means on any particular date (a) the lowest reported trading price per share of Common Stock on such date on the Trading

Market (as reported by Bloomberg L.P. at 4:15 p.m. (New York City time)), (b) if there is no such price on such date, then the lowest

trading price on the Trading Market on the date nearest preceding such date (as reported by Bloomberg L.P. at 4:15 p.m. (New York City

time)), (c) if the Common Stock is not then listed or quoted on a Trading Market and if prices for the Common Stock are then reported

on The Pink Open Market (or a similar organization or agency succeeding to its functions of reporting prices), the lowest trading price

per share of the Common Stock so reported, or (d) if the shares of Common Stock are not then publicly traded the fair market value as

of such date of a share of Common Stock as determined by an independent appraiser selected in good faith by the Purchasers of a majority

in interest of the shares then outstanding and reasonably acceptable to the Company, the fees and expenses of which shall be paid by

the Company.

6

“Transaction

Documents” means this Agreement, the Certificate of Designation, the Warrants, the Registration Rights Agreement, the Lock-Up

Agreement, the Voting Agreement, all exhibits and schedules thereto and hereto and any other documents or agreements executed in connection

with the transactions contemplated hereunder.

“Transfer

Agent” means Computershare Trust Company, N.A., the current transfer agent of the Company, and any successor transfer agent

of the Company.

“Underlying

Shares” means the Conversion Shares and the Warrant Shares.

“Variable

Rate Transaction” shall have the meaning ascribed to such term in Section 4.13(b).

“Vesting

Warrants” means, collectively, the Common Stock Vesting Warrants delivered to the Purchasers at the Closing in accordance with

Section 2.2(a) hereof, which Vesting Warrants shall vest pursuant to the terms therein and have a term of exercise that expires five

(5) years from the date on which the applicable Purchaser elects to purchase the applicable Greenshoe Securities, in the form of Exhibit

D attached hereto.

“Vesting

Warrant Shares” means the shares of Common Stock issuable upon exercise of the Vesting Warrants.

“Voting

Agreement” means the written agreement, in the form of Exhibit F attached hereto, of all of the officers and directors,

and the stockholders party thereto holding more than 10% of the issued and outstanding shares of Common Stock on the date hereof, to

vote all Common Stock over which such Persons have voting control as of the record date for the meeting of stockholders of the Company

referenced therein.

“VWAP”

means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed

or quoted on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date)

on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg L.P. (based on a Trading Day from 9:30

a.m. (New York City time) to 4:02 p.m. (New York City time)), (b) if OTCQB Venture Market (“OTCQB”) or OTCQX Best Market

(“OTCQX”) is not a Trading Market, the volume weighted average price of the Common Stock for such date (or the nearest preceding

date) on OTCQB or OTCQX as applicable, (c) if the Common Stock is not then listed or quoted for trading on OTCQB or OTCQX and if prices

for the Common Stock are then reported on the Pink Open Market (“Pink Market”) operated by OTC Markets Group, Inc. (or a

similar organization or agency succeeding to its functions of reporting prices), the most recent bid price per share of the Common Stock

so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser selected

in good faith by the Company and reasonably acceptable to the Purchasers of a majority in interest of the Securities then outstanding,

the fees and expenses of which shall be paid by the Company.

“Warrants”

means, collectively, the Common Stock Warrants and the Vesting Warrants.

“Warrant

Shares” means, collectively, the Common Stock Warrant Shares and the Vesting Warrant Shares.

7

ARTICLE

II.

PURCHASE

AND SALE

2.1

Closing. On the Closing Date, upon the terms and subject to the conditions set forth herein, substantially concurrent with the

execution and delivery of this Agreement by the parties hereto, the Company agrees to sell, and the Purchasers, severally and not jointly,

agree to purchase, up to an aggregate of $8,277,778 of shares of Preferred Stock for an aggregate purchase price equal to $7,450,000.

The aggregate number of shares of Preferred Stock sold hereunder on the Closing Date shall be up to 8,277.778. Each Purchaser shall deliver

to the Company, via wire transfer, immediately available funds equal to such Purchasers Subscription Amount and the Company shall deliver

to each Purchaser its respective shares of Preferred Stock and Warrants as determined pursuant to Section 2.2(a), and the Company and

each Purchaser shall deliver the other items set forth in Section 2.2 deliverable at the Closing. Upon satisfaction of the covenants

and conditions set forth in Sections 2.2 and 2.3, the Closing shall occur at the offices of Five Narrow Lane Counsel or such other location

as the parties shall mutually agree and take place remotely by electronic transfer of the Closing documentation.

2.2 Deliveries.

(a)

On or prior to the Closing Date, the Company shall deliver or cause to be delivered to each Purchaser the following:

(i)

this Agreement duly executed by the Company;

(ii)

a legal opinion of Company Counsel, substantially in the form of Exhibit D attached hereto;

(iii)

confirmation of book-entry or a certificate evidencing the applicable number of shares of Preferred Stock registered in the name of such

Purchaser and evidence of the filing and acceptance of the Certificate of Designation from the Secretary of State of Delaware;

(iv)

a Warrant registered in the name of such Purchaser to purchase up to a number of shares of Common Stock equal to 100% of such Purchaser’s

Conversion Shares;

(v)

a Vesting Warrant to purchase up to an additional number of shares of Common stock equal to the number of Greenshoe Conversion Shares

(as defined herein) issuable hereunder in full, registered in the name of such Purchaser.

(vi)

the Company shall have provided each Purchaser with the Company’s wire instructions, on Company letterhead and executed by the

Chief Executive Officer or Chief Financial Officer;

(vii)

the Voting Agreement duly executed by the Company, each officer and director of the Company, and the stockholders party thereto holding

more than 10% of the issued and outstanding shares of Common Stock on the date hereof;

(viii)

the Lock-Up Agreements; and

(ix)

the Registration Rights Agreement duly executed by the Company.

(b)

On or prior to the Closing Date, each Purchaser shall deliver or cause to be delivered to the Company, the following:

(i)

this Agreement duly executed by such Purchaser;

(ii)

such Purchaser’s Subscription Amount by wire transfer to the account specified in writing by the Company; and

8

(iii)

the Registration Rights Agreement duly executed by such Purchaser.

2.3

Closing Conditions.

(a)

The obligations of the Company hereunder in connection with the Closing are subject to the following conditions being met:

(i)

the accuracy in all material respects (or, to the extent representations or warranties are qualified by materiality, in all respects)

on the Closing Date of the representations and warranties of the Purchasers contained herein (unless as of a specific date therein in

which case they shall be accurate in all material respects (or, to the extent representations or warranties are qualified by materiality,

in all respects) as of such date);

(ii)

all obligations, covenants and agreements of each Purchaser required to be performed at or prior to the Closing Date shall have been

performed; and

(iii)

the delivery by each Purchaser of the items set forth in Section 2.2(b) of this Agreement.

(b)

The respective obligations of the Purchasers hereunder in connection with the Closing are subject to the following conditions being met:

(i)

the accuracy in all material respects (or, to the extent representations or warranties are qualified by materiality or Material Adverse

Effect, in all respects) on the Closing Date of the representations and warranties of the Company contained herein (unless as of a specific

date therein in which case they shall be accurate in all material respects or, to the extent representations or warranties are qualified

by materiality or Material Adverse Effect, in all respects) as of such date);

(ii)

all obligations, covenants and agreements of the Company required to be performed at or prior to the Closing Date shall have been performed;

(iii)

the delivery by the Company of the items set forth in Section 2.2(a) of this Agreement;

(iv)

there shall have been no Material Adverse Effect with respect to the Company since the date hereof; and

(v)

from the date hereof to the Closing Date, trading in the Common Stock shall not have been suspended by the Commission or the Company’s

principal Trading Market and, at any time prior to the Closing Date, trading in securities generally as reported by Bloomberg L.P. shall

not have been suspended or limited, or minimum prices shall not have been established on securities whose trades are reported by such

service, or on any Trading Market, nor shall a banking moratorium have been declared either by the United States or New York State authorities

nor shall there have occurred any material outbreak or escalation of hostilities or other national or international calamity of such

magnitude in its effect on, or any material adverse change in, any financial market which, in each case, in the reasonable judgment of

such Purchaser, makes it impracticable or inadvisable to purchase the Securities at the Closing.

9

2.4

Greenshoe Rights.

(a)

From the date hereof until the date that no Greenshoe Securities (as defined herein) remain available for purchase, each Purchaser may,

in its sole determination, elect to purchase, severally and not jointly with the other Purchasers and, subject to the proviso below,

in one or more closings, shares of Preferred Stock with an aggregate Stated Value thereof of up to $33,333,333.33 (such securities, the

“Greenshoe Securities” and such shares of Common Stock issuable upon conversion of such Greenshoe Securities (the

“Greenshoe Conversion Shares”) and such right to receive the Greenshoe Securities pursuant to this Section 2.4, the

“Greenshoe Rights”), for an aggregate purchase price equal to $30,000,000, provided the conversion price of the Preferred

Stock and Exercise Price of the Vesting Warrants shall be equal to the Conversion Price (as set forth in Section 6(b) of the Certificate

of Designation) and the Warrants shall be adjusted pursuant to the adjustment provisions thereunder. Each Purchaser is hereby entitled

to exercise its respective Greenshoe Rights for an amount of Greenshoe Securities equal to the ratio of such Purchaser’s original

Subscription Amount to the original aggregate Subscription Amount of all Purchasers, provided that, in connection with the exercise of

Greenshoe Rights, such Purchaser shall purchase Greenshoe Securities having a Stated Value at least equal to the lesser of (i) $100,000

and (ii) the balance of the Greenshoe Rights attributable to such Purchaser hereunder.

(b)

Any Greenshoe Right exercised by a Purchaser shall close within 3 Trading Days of a duly delivered exercise notice by the exercising

party (each such closing date, a “Greenshoe Closing”); provided, however, within one (1) Trading Day of receipt of

an exercise notice hereunder, the Company shall notify all Purchasers hereunder of such exercise, the time of such exercise and of the

new Adjusted Price (if applicable and as defined Section 6(b) of the Certificate of Designation), which Adjusted Price shall be deemed

the new Conversion Price of the Preferred Stock effective as of the delivery of such notice. Any additional investment in the Greenshoe

Securities shall be on terms identical to those set forth in the Transaction Documents, mutatis mutandis. In order to effectuate

a purchase and sale of the Greenshoe Securities, the Company and the Purchasers shall enter into a Securities Purchase Agreement identical

to this Agreement, mutatis mutandis and shall include updated disclosure schedules but shall exclude the issuance of additional

Vesting Warrants or the delivery of Voting Agreements, Lock-Ups and a Registration Rights Agreement.

ARTICLE

III.

REPRESENTATIONS

AND WARRANTIES

3.1

Representations and Warranties of the Company. Except as set forth in the Disclosure Schedules provided with this Agreement (the

“Disclosure Schedules”), which shall be deemed a part hereof and shall qualify any representation or otherwise made

herein to the extent of the disclosure contained in the corresponding section of the Disclosure Schedules, the Company hereby makes the

following representations and warranties to each Purchaser as of the date hereof and as of the Closing Date:

(a)

Subsidiaries. All of the direct and indirect subsidiaries of the Company are set forth on Schedule 3.1(a). The Company

owns, directly or indirectly, all of the capital stock or other equity interests of each Subsidiary free and clear of any Liens, and

all of the issued and outstanding shares of capital stock of each Subsidiary are validly issued and are fully paid, non-assessable and

free of preemptive and similar rights to subscribe for or purchase securities. If the Company has no subsidiaries, all other references

to the Subsidiaries or any of them in the Transaction Documents shall be disregarded.

(b)

Organization and Qualification. The Company and each of the Subsidiaries is an entity duly incorporated or otherwise organized,

validly existing and in good standing under the laws of the jurisdiction of its incorporation or organization, with the requisite power

and authority to own and use its properties and assets and to carry on its business as currently conducted. Neither the Company nor any

Subsidiary is in violation nor default of any of the provisions of its respective certificate or articles of incorporation, bylaws or

other organizational or charter documents. Each of the Company and the Subsidiaries is duly qualified to conduct business and is in good

standing as a foreign corporation or other entity in each jurisdiction in which the nature of the business conducted or property owned

by it makes such qualification necessary, except where the failure to be so qualified or in good standing, as the case may be, could

not have or reasonably be expected to result in: (i) a material adverse effect on the legality, validity or enforceability of any Transaction

Document, (ii) a material adverse effect on the results of operations, assets, business or condition (financial or otherwise) of the

Company and the Subsidiaries, taken as a whole, or (iii) a material adverse effect on the Company’s ability to perform in any material

respect on a timely basis its obligations under any Transaction Document (any of (i), (ii) or (iii), a “Material Adverse Effect”)

and no Proceeding has been instituted in any such jurisdiction revoking, limiting or curtailing or seeking to revoke, limit or curtail

such power and authority or qualification.

10

(c)

Authorization; Enforcement. The Company has the requisite corporate power and authority to enter into and to consummate the transactions

contemplated by this Agreement and each of the other Transaction Documents and otherwise to carry out its obligations hereunder and thereunder.

The execution and delivery of this Agreement and each of the other Transaction Documents by the Company and the consummation by it of

the transactions contemplated hereby and thereby have been duly authorized by all necessary action on the part of the Company and no

further action is required by the Company, the Board of Directors or the Company’s stockholders in connection herewith or therewith

other than in connection with the Required Approvals. This Agreement and each other Transaction Document to which it is a party has been

(or upon delivery will have been) duly executed by the Company and, when delivered in accordance with the terms hereof and thereof, will

constitute the valid and binding obligation of the Company enforceable against the Company in accordance with its terms, except (i) as

limited by general equitable principles and applicable bankruptcy, insolvency, reorganization, moratorium and other laws of general application

affecting enforcement of creditors’ rights generally, (ii) as limited by laws relating to the availability of specific performance,

injunctive relief or other equitable remedies and (iii) insofar as indemnification and contribution provisions may be limited by applicable

law.

(d)

No Conflicts. The execution, delivery and performance by the Company of this Agreement and the other Transaction Documents to

which it is a party, the issuance and sale of the Securities and the consummation by it of the transactions contemplated hereby and thereby

do not and will not (i) conflict with or violate any provision of the Company’s or any Subsidiary’s certificate or articles

of incorporation, bylaws or other organizational or charter documents, or (ii) conflict with, or constitute a default (or an event that

with notice or lapse of time or both would become a default) under, result in the creation of any Lien upon any of the properties or

assets of the Company or any Subsidiary, or give to others any rights of termination, amendment, anti-dilution or similar adjustments,

acceleration or cancellation (with or without notice, lapse of time or both) of, any agreement, credit facility, debt or other instrument

(evidencing a Company or Subsidiary debt or otherwise) or other understanding to which the Company or any Subsidiary is a party or by

which any property or asset of the Company or any Subsidiary is bound or affected, or (iii) subject to the Required Approvals, conflict

with or result in a violation of any law, rule, regulation, order, judgment, injunction, decree or other restriction of any court or

governmental authority to which the Company or a Subsidiary is subject (including federal and state securities laws and regulations),

or by which any property or asset of the Company or a Subsidiary is bound or affected; except in the case of each of clauses (ii) and

(iii), such as could not have or reasonably be expected to result in a Material Adverse Effect.

(e)

Filings, Consents and Approvals. Except as set forth on Schedule 3.1(e), the Company is not required to obtain any consent, waiver,

authorization or order of, give any notice to, or make any filing or registration with, any court or other federal, state, local or other

governmental authority or other Person in connection with the execution, delivery and performance by the Company of the Transaction Documents,

other than: (i) the filings required pursuant to Section 4.6 of this Agreement, (ii) the filing with the Commission pursuant to the Registration

Rights Agreement, (iii) the notice and/or application(s) to each applicable Trading Market for the issuance and sale of the Securities

and the listing of the Underlying Shares for trading thereon in the time and manner required thereby, (iv) the filing of Form D with

the Commission and such filings as are required to be made under applicable state securities laws and (v) Shareholder Approval (collectively,

the “Required Approvals”).

(f)

Issuance of the Securities. The Securities are duly authorized and, when issued and paid for in accordance with the applicable

Transaction Documents, will be duly and validly issued, fully paid and nonassessable, free and clear of all Liens imposed by the Company

other than restrictions on transfer provided for in the Transaction Documents. The Underlying Shares, when issued in accordance with

the terms of the Transaction Documents, will be validly issued, fully paid and nonassessable, free and clear of all Liens imposed by

the Company other than restrictions on transfer provided for in the Transaction Documents. The Company has reserved from its duly authorized

capital stock a number of shares of Common Stock for issuance of the Underlying Shares at least equal to the Required Minimum on the

date hereof.

11

(g)

Capitalization. The capitalization of the Company as of the date hereof is as set forth on Schedule 3.1(g), which Schedule

3.1(g) shall also include the number of shares of Common Stock owned beneficially, and of record, by Affiliates of the Company as

of the date hereof. Except as set forth on Schedule 3.1(g), the Company has not issued any capital stock since its most recently

filed periodic report under the Exchange Act, other than pursuant to the exercise of employee stock incentives under the Company’s

stock incentive plans, the issuance of shares of Common Stock to employees pursuant to the Company’s employee stock purchase plans

and pursuant to the conversion and/or exercise of Common Stock Equivalents outstanding as of the date of the most recently filed periodic

report under the Exchange Act. No Person has any right of first refusal, preemptive right, right of participation, or any similar right

to participate in the transactions contemplated by the Transaction Documents. Except as set forth on Schedule 3.1(g), there are

no outstanding options, warrants, scrip rights to subscribe to, calls or commitments of any character whatsoever relating to, or securities,

rights or obligations convertible into or exercisable or exchangeable for, or giving any Person any right to subscribe for or acquire,

any shares of Common Stock or the capital stock of any Subsidiary, or contracts, commitments, understandings or arrangements by which

the Company or any Subsidiary is or may become bound to issue additional shares of Common Stock or Common Stock Equivalents or capital

stock of any Subsidiary. The issuance and sale of the Securities will not obligate the Company or any Subsidiary to issue shares of Common

Stock or other securities to any Person (other than the Purchasers). There are no outstanding securities or instruments of the Company

or any Subsidiary with any provision that adjusts the exercise, conversion, exchange or reset price of such security or instrument upon

an issuance of securities by the Company or any Subsidiary. There are no outstanding securities or instruments of the Company or any

Subsidiary that contain any redemption or similar provisions, and there are no contracts, commitments, understandings or arrangements

by which the Company or any Subsidiary is or may become bound to redeem a security of the Company or such Subsidiary. Except as set forth

on Schedule 3.1(g), the Company does not have any stock appreciation rights or “phantom stock” plans or agreements

or any similar plan or agreement. All of the outstanding shares of capital stock of the Company are duly authorized, validly issued,

fully paid and nonassessable, have been issued in compliance with all federal and state securities laws, and none of such outstanding

shares was issued in violation of any preemptive rights or similar rights to subscribe for or purchase securities. Except for the Required

Approvals, no further approval or authorization of any stockholder, the Board of Directors or others is required for the issuance and

sale of the Securities. Other than the Voting Agreement, there are no stockholders agreements, voting agreements or other similar agreements

with respect to the Company’s capital stock to which the Company is a party or, to the knowledge of the Company, between or among

any of the Company’s stockholders.

(h)

SEC Reports; Financial Statements. The Company has filed all reports, schedules, forms, statements and other documents required

to be filed by the Company under the Securities Act and the Exchange Act, including pursuant to Section 13(a) or 15(d) thereof, for the

two years preceding the date hereof (or such shorter period as the Company was required by law or regulation to file such material) (the

foregoing materials, including the exhibits thereto and documents incorporated by reference therein, being collectively referred to herein

as the “SEC Reports”) on a timely basis or has received a valid extension of such time of filing and has filed any

such SEC Reports prior to the expiration of any such extension. As of their respective dates, the SEC Reports complied in all material

respects with the requirements of the Securities Act and the Exchange Act, as applicable, and none of the SEC Reports, when filed, contained

any untrue statement of a material fact or omitted to state a material fact required to be stated therein or necessary in order to make

the statements therein, in the light of the circumstances under which they were made, not misleading. The Company has never been an issuer

subject to Rule 144(i) under the Securities Act. The financial statements of the Company included in the SEC Reports comply in all material

respects with applicable accounting requirements and the rules and regulations of the Commission with respect thereto as in effect at

the time of filing. Such financial statements have been prepared in accordance with United States generally accepted accounting principles

applied on a consistent basis during the periods involved (“GAAP”), except as may be otherwise specified in such financial

statements or the notes thereto and except that unaudited financial statements may not contain all footnotes required by GAAP, and fairly

present in all material respects the financial position of the Company and its consolidated Subsidiaries as of and for the dates thereof

and the results of operations and cash flows for the periods then ended, subject, in the case of unaudited statements, to normal, immaterial,

year-end audit adjustments.

12

(i)

Material Changes; Undisclosed Events, Liabilities or Developments. Since the date of the latest audited financial statements included

within the SEC Reports, except as set forth on Schedule 3.1(i), (i) there has been no event, occurrence or development that has

had or that could reasonably be expected to result in a Material Adverse Effect, (ii) the Company has not incurred any liabilities (contingent

or otherwise) other than (A) trade payables and accrued expenses incurred in the ordinary course of business consistent with past practice

and (B) liabilities not required to be reflected in the Company’s financial statements pursuant to GAAP or disclosed in filings

made with the Commission, (iii) the Company has not altered its method of accounting, (iv) the Company has not declared or made any dividend

or distribution of cash or other property to its stockholders or purchased, redeemed or made any agreements to purchase or redeem any

shares of its capital stock and (v) the Company has not issued any equity securities to any officer, director or Affiliate, except pursuant

to existing Company stock incentive plans. The Company does not have pending before the Commission any request for confidential treatment

of information. Except for the issuance of the Securities contemplated by this Agreement or as set forth on Schedule 3.1(i), no

event, liability, fact, circumstance, occurrence or development has occurred or exists or is reasonably expected to occur or exist with

respect to the Company or its Subsidiaries or their respective businesses, properties, operations, assets or financial condition, that

would be required to be disclosed by the Company under applicable securities laws at the time this representation is made or deemed made

that has not been publicly disclosed at least 1 Trading Day prior to the date that this representation is made.

(j)

Litigation. Except as set forth on Schedule 3.1(j), there is no action, suit, inquiry, notice of violation, proceeding

or investigation pending or, to the knowledge of the Company, threatened against or affecting the Company, any Subsidiary or any of their

respective properties before or by any court, arbitrator, governmental or administrative agency or regulatory authority (federal, state,

county, local or foreign) (collectively, an “Action”). None of the Actions set forth on Schedule 3.1(j), (i)

adversely affects or challenges the legality, validity or enforceability of any of the Transaction Documents or the Securities or (ii)

could, if there were an unfavorable decision, have or reasonably be expected to result in a Material Adverse Effect. Neither the Company

nor any Subsidiary, nor any director or officer thereof, is or has been the subject of any Action involving a claim of violation of or

liability under federal or state securities laws or a claim of breach of fiduciary duty. There has not been, and to the knowledge of

the Company, there is not pending or contemplated, any investigation by the Commission involving the Company or any current or former

director or officer of the Company. The Commission has not issued any stop order or other order suspending the effectiveness of any registration

statement filed by the Company or any Subsidiary under the Exchange Act or the Securities Act.

(k)

Labor Relations. No labor dispute exists or, to the knowledge of the Company, is imminent with respect to any of the employees

of the Company, which could reasonably be expected to result in a Material Adverse Effect. None of the Company’s or its Subsidiaries’

employees is a member of a union that relates to such employee’s relationship with the Company or such Subsidiary, and neither

the Company nor any of its Subsidiaries is a party to a collective bargaining agreement, and the Company and its Subsidiaries believe

that their relationships with their employees are good. To the knowledge of the Company, no executive officer of the Company or any Subsidiary,

is, or is now expected to be, in violation of any material term of any employment contract, confidentiality, disclosure or proprietary

information agreement or non-competition agreement, or any other contract or agreement or any restrictive covenant in favor of any third

party, and the continued employment of each such executive officer does not subject the Company or any of its Subsidiaries to any liability

with respect to any of the foregoing matters. The Company and its Subsidiaries are in compliance with all U.S. federal, state, local

and foreign laws and regulations relating to employment and employment practices, terms and conditions of employment and wages and hours,

except where the failure to be in compliance could not, individually or in the aggregate, reasonably be expected to have a Material Adverse

Effect.

13

(l)

Compliance. Neither the Company nor any Subsidiary: (i) is in default under or in violation of (and no event has occurred that

has not been waived that, with notice or lapse of time or both, would result in a default by the Company or any Subsidiary under), nor

has the Company or any Subsidiary received notice of a claim that it is in default under or that it is in violation of, any indenture,

loan or credit agreement or any other agreement or instrument to which it is a party or by which it or any of its properties is bound

(whether or not such default or violation has been waived), (ii) is in violation of any judgment, decree or order of any court, arbitrator

or other governmental authority or (iii) is or has been in violation of any statute, rule, ordinance or regulation of any governmental

authority, including without limitation all foreign, federal, state and local laws relating to taxes, environmental protection, occupational

health and safety, product quality and safety and employment and labor matters, except in each case as could not have or reasonably be

expected to result in a Material Adverse Effect.

(m)

Environmental Laws. The Company and its Subsidiaries (i) are in compliance with all federal, state, local and foreign laws relating

to pollution or protection of human health or the environment (including ambient air, surface water, groundwater, land surface or subsurface

strata), including laws relating to emissions, discharges, releases or threatened releases of chemicals, pollutants, contaminants, or

toxic or hazardous substances or wastes (collectively, “Hazardous Materials”) into the environment, or otherwise relating

to the manufacture, processing, distribution, use, treatment, storage, disposal, transport or handling of Hazardous Materials, as well

as all authorizations, codes, decrees, demands, or demand letters, injunctions, judgments, licenses, notices or notice letters, orders,

permits, plans or regulations, issued, entered, promulgated or approved thereunder (“Environmental Laws”); (ii) have

received all permits licenses or other approvals required of them under applicable Environmental Laws to conduct their respective businesses;

and (iii) are in compliance with all terms and conditions of any such permit, license or approval where in each clause (i), (ii) and

(iii), the failure to so comply could be reasonably expected to have, individually or in the aggregate, a Material Adverse Effect.

(n)

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate

federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as described in the SEC Reports,

except where the failure to possess such permits could not reasonably be expected to result in a Material Adverse Effect (“Material

Permits”), and neither the Company nor any Subsidiary has received any notice of proceedings relating to the revocation or

modification of any Material Permit.

(o)

Title to Assets. The Company and the Subsidiaries have good and marketable title in fee simple to all real property owned by them

and good and marketable title in all personal property owned by them that is material to the business of the Company and the Subsidiaries,

in each case free and clear of all Liens, except for (i) Liens as do not materially affect the value of such property and do not materially

interfere with the use made and proposed to be made of such property by the Company and the Subsidiaries and (ii) Liens for the payment

of federal, state or other taxes, for which appropriate reserves have been made therefor in accordance with GAAP and, the payment of

which is neither delinquent nor subject to penalties. Any real property and facilities held under lease by the Company and the Subsidiaries

are held by them under valid, subsisting and enforceable leases with which the Company and the Subsidiaries are in compliance.

(p)

Intellectual Property. The Company and the Subsidiaries have, or have rights to use, all patents, patent applications, trademarks,

trademark applications, service marks, trade names, trade secrets, inventions, copyrights, licenses and other intellectual property rights

and similar rights necessary or required for use in connection with their respective businesses as described in the SEC Reports and which

the failure to so have could have a Material Adverse Effect (collectively, the “Intellectual Property Rights”). None

of, and neither the Company nor any Subsidiary has received a notice (written or otherwise) that any of, the Intellectual Property Rights

has expired, terminated or been abandoned, or is expected to expire or terminate or be abandoned, within two (2) years from the date

of this Agreement. Neither the Company nor any Subsidiary has received, since the date of the latest audited financial statements included

within the SEC Reports, a written notice of a claim or otherwise has any knowledge that the Intellectual Property Rights violate or infringe

upon the rights of any Person, except as could not have or reasonably be expected to not have a Material Adverse Effect. To the knowledge

of the Company, all such Intellectual Property Rights are enforceable and there is no existing infringement by another Person of any

of the Intellectual Property Rights. The Company and its Subsidiaries have taken reasonable security measures to protect the secrecy,

confidentiality and value of all of their intellectual properties, except where failure to do so could not, individually or in the aggregate,

reasonably be expected to have a Material Adverse Effect.

14

(q)

Insurance. The Company and the Subsidiaries are insured by insurers of recognized financial responsibility against such losses

and risks and in such amounts as are prudent and customary in the businesses in which the Company and the Subsidiaries are engaged. Neither

the Company nor any Subsidiary has any reason to believe that it will not be able to renew its existing insurance coverage as and when

such coverage expires or to obtain similar coverage from similar insurers as may be necessary to continue its business without a significant

increase in cost.

(r)

Transactions with Affiliates and Employees. Except as set forth on Schedule 3.1(r), none of the officers or directors of

the Company or any Subsidiary and, to the knowledge of the Company, none of the employees of the Company or any Subsidiary is presently

a party to any transaction with the Company or any Subsidiary (other than for services as employees, officers and directors), including

any contract, agreement or other arrangement providing for the furnishing of services to or by, providing for rental of real or personal

property to or from, providing for the borrowing of money from or lending of money to or otherwise requiring payments to or from any

officer, director or such employee or, to the knowledge of the Company, any entity in which any officer, director, or any such employee

has a substantial interest or is an officer, director, trustee, stockholder, member or partner, in each case in excess of $120,000 other

than for (i) payment of salary or consulting fees for services rendered, (ii) reimbursement for expenses incurred on behalf of the Company

and (iii) other employee benefits, including stock option agreements under any stock incentive plan of the Company.

(s)

Sarbanes-Oxley; Internal Accounting Controls. The Company and the Subsidiaries are in compliance with any and all applicable requirements

of the Sarbanes-Oxley Act of 2002, as amended that are effective as of the date hereof, and any and all applicable rules and regulations

promulgated by the Commission thereunder that are effective as of the date hereof and as of the Closing Date. The Company and the Subsidiaries

maintain a system of internal accounting controls sufficient to provide reasonable assurance that: (i) transactions are executed in accordance

with management’s general or specific authorizations, (ii) transactions are recorded as necessary to permit preparation of financial

statements in conformity with GAAP and to maintain asset accountability, (iii) access to assets is permitted only in accordance with

management’s general or specific authorization, and (iv) the recorded accountability for assets is compared with the existing assets

at reasonable intervals and appropriate action is taken with respect to any differences. The Company and the Subsidiaries have established

disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the Company and the Subsidiaries and

designed such disclosure controls and procedures to ensure that information required to be disclosed by the Company in the reports it

files or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the Commission’s

rules and forms. The Company’s certifying officers have evaluated the effectiveness of the disclosure controls and procedures of

the Company and the Subsidiaries as of the end of the period covered by the most recently filed periodic report under the Exchange Act

(such date, the “Evaluation Date”). The Company presented in its most recently filed periodic report under the Exchange

Act the conclusions of the certifying officers about the effectiveness of the disclosure controls and procedures based on their evaluations

as of the Evaluation Date. Since the Evaluation Date, there have been no changes in the internal control over financial reporting (as

such term is defined in the Exchange Act) of the Company and its Subsidiaries that have materially affected, or is reasonably likely

to materially affect, the internal control over financial reporting of the Company and its Subsidiaries.

15

(t)

Certain Fees. Except for fees payable by the Company as set forth on Schedule 3.1(t), no brokerage or finder’s fees

or commissions are or will be payable by the Company or any Subsidiary to any broker, financial advisor or consultant, finder, placement

agent, investment banker, bank or other Person with respect to the transactions contemplated by the Transaction Documents. The Purchasers

shall have no obligation with respect to any fees or with respect to any claims made by or on behalf of other Persons for fees of a type

contemplated in this Section that may be due in connection with the transactions contemplated by the Transaction Documents.

(u)

Private Placement. Assuming the accuracy of the Purchasers’ representations and warranties set forth in Section 3.2, no

registration under the Securities Act is required for the offer and sale of the Securities by the Company to the Purchasers as contemplated

hereby. The issuance and sale of the Securities hereunder does not contravene the rules and regulations of the Trading Market.

(v)

Investment Company. The Company is not, and is not an Affiliate of, and immediately after receipt of payment for the Securities,

will not be or be an Affiliate of, an “investment company” within the meaning of the Investment Company Act of 1940, as amended.

The Company shall conduct its business in a manner so that it will not become an “investment company” subject to registration

under the Investment Company Act of 1940, as amended.

(w)

Registration Rights. Other than the rights of the Purchasers set forth in the Registration Rights Agreement and the Registration

Rights Agreement, dated as of May 12, 2025, between the Company and the holders party thereto, no Person has any right to cause the Company

or any Subsidiary to effect the registration under the Securities Act of any securities of the Company or any Subsidiary.

(x)

Listing and Maintenance Requirements. The Common Stock is registered pursuant to Section 12(b) or 12(g) of the Exchange Act, and

the Company has taken no action designed to, or which to its knowledge is likely to have the effect of, terminating the registration

of the Common Stock under the Exchange Act nor has the Company received any notification that the Commission is contemplating terminating

such registration. Except as set forth on Schedule 3.1(x), the Company has not, in the 12 months preceding the date hereof, received

notice from any Trading Market on which the Common Stock is or has been listed or quoted to the effect that the Company is not in compliance

with the listing or maintenance requirements of such Trading Market. Except as set forth on Schedule 3.1(x), Company is, and has

no reason to believe that it will not in the foreseeable future continue to be, in compliance with all such listing and maintenance requirements.

The Common Stock is currently eligible for electronic transfer through the Depository Trust Company or another established clearing corporation

and the Company is current in payment of the fees to the Depository Trust Company (or such other established clearing corporation) in

connection with such electronic transfer.

(y)

Application of Takeover Protections. The Company and the Board of Directors have taken all necessary action, if any, in order

to render inapplicable any control share acquisition, business combination, poison pill (including any distribution under a rights agreement)

or other similar anti-takeover provision under the Company’s certificate of incorporation (or similar charter documents) or the

laws of its state of incorporation that is or could become applicable to the Purchasers as a result of the Purchasers and the Company

fulfilling their obligations or exercising their rights under the Transaction Documents, including without limitation as a result of

the Company’s issuance of the Securities and the Purchasers’ ownership of the Securities.

(z)

Disclosure. Except with respect to the material terms and conditions of the transactions contemplated by the Transaction Documents,

the Company confirms that neither it nor any other Person acting on its behalf has provided any of the Purchasers or their agents or

counsel with any information that it believes constitutes or might constitute material, non-public information. The Company understands

and confirms that the Purchasers will rely on the foregoing representation in effecting transactions in securities of the Company. All

of the disclosure furnished by or on behalf of the Company to the Purchasers regarding the Company and its Subsidiaries, their respective

businesses and the transactions contemplated hereby, including the Disclosure Schedules to this Agreement, is true and correct and does

not contain any untrue statement of a material fact or omit to state any material fact necessary in order to make the statements made

therein, in the light of the circumstances under which they were made, not misleading. The press releases disseminated by the Company

during the twelve months preceding the date of this Agreement taken as a whole do not contain any untrue statement of a material fact

or omit to state a material fact required to be stated therein or necessary in order to make the statements therein, in the light of

the circumstances under which they were made and when made, not misleading. The Company acknowledges and agrees that no Purchaser makes

or has made any representations or warranties with respect to the transactions contemplated hereby other than those specifically set

forth in Section 3.2 hereof.

16

(aa)

No Integrated Offering. Assuming the accuracy of the Purchasers’ representations and warranties set forth in Section 3.2,

neither the Company, nor any of its Affiliates, nor any Person acting on its or their behalf has, directly or indirectly, made any offers

or sales of any security or solicited any offers to buy any security, under circumstances that would cause this offering of the Securities

to be integrated with prior offerings by the Company for purposes of (i) the Securities Act which would require the registration of any

such securities under the Securities Act, or (ii) any applicable shareholder approval provisions of any Trading Market on which any of

the securities of the Company are listed or designated.

(bb)

Solvency. Based on the consolidated financial condition of the Company as of the Closing Date, after giving effect to the receipt

by the Company of the proceeds from the sale of the Securities hereunder (i) the fair saleable value of the Company’s assets exceeds

the amount that will be required to be paid on or in respect of the Company’s existing debts and other liabilities (including known

contingent liabilities) as they mature, (ii) the Company’s assets do not constitute unreasonably small capital to carry on its

business as now conducted and as proposed to be conducted including its capital needs taking into account the particular capital requirements

of the business conducted by the Company, consolidated and projected capital requirements and capital availability thereof, and (iii)

the current cash flow of the Company, together with the proceeds the Company would receive, were it to liquidate all of its assets, after

taking into account all anticipated uses of the cash, would be sufficient to pay all amounts on or in respect of its liabilities when

such amounts are required to be paid. The Company does not intend to incur debts beyond its ability to pay such debts as they mature

(taking into account the timing and amounts of cash to be payable on or in respect of its debt). The Company has no knowledge of any

facts or circumstances which lead it to believe that it will file for reorganization or liquidation under the bankruptcy or reorganization

laws of any jurisdiction within one year from the Closing Date. Schedule 3.1(bb) sets forth as of the date hereof all outstanding

secured and unsecured Indebtedness of the Company or any Subsidiary, or for which the Company or any Subsidiary has commitments. For

the purposes of this Agreement, “Indebtedness” means (x) any liabilities for borrowed money in excess of $50,000 (other

than trade accounts payable incurred in the ordinary course of business), (y) all guaranties, endorsements and other contingent obligations

in respect of indebtedness of others, whether or not the same are or should be reflected in the Company’s consolidated balance

sheet (or the notes thereto), except guaranties by endorsement of negotiable instruments for deposit or collection or similar transactions

in the ordinary course of business; and (z) the present value of any lease payments in excess of $50,000 due under leases required to

be capitalized in accordance with GAAP. Neither the Company nor any Subsidiary is in default with respect to any Indebtedness.

(cc)

Tax Status. Except for matters that would not, individually or in the aggregate, have or reasonably be expected to result in a

Material Adverse Effect, the Company and its Subsidiaries each (i) has made or filed all United States federal, state and local income

and all foreign income and franchise tax returns, reports and declarations required by any jurisdiction to which it is subject, (ii)

has paid all taxes and other governmental assessments and charges that are material in amount, shown or determined to be due on such

returns, reports and declarations and (iii) has set aside on its books provision reasonably adequate for the payment of all material

taxes for periods subsequent to the periods to which such returns, reports or declarations apply. There are no unpaid taxes in any material

amount claimed to be due by the taxing authority of any jurisdiction, and the officers of the Company or of any Subsidiary know of no

basis for any such claim.

17

(dd)

No General Solicitation. Neither the Company nor any Person acting on behalf of the Company has offered or sold any of the Securities

by any form of general solicitation or general advertising. The Company has offered the Securities for sale only to the Purchasers and

certain other “accredited investors” within the meaning of Rule 501 under the Securities Act.

(ee)

Foreign Corrupt Practices. Neither the Company nor any Subsidiary, nor to the knowledge of the Company or any Subsidiary, any

agent or other person acting on behalf of the Company or any Subsidiary, has (i) directly or indirectly, used any funds for unlawful

contributions, gifts, entertainment or other unlawful expenses related to foreign or domestic political activity, (ii) made any unlawful

payment to foreign or domestic government officials or employees or to any foreign or domestic political parties or campaigns from corporate

funds, (iii) failed to disclose fully any contribution made by the Company or any Subsidiary (or made by any person acting on its behalf

of which the Company is aware) which is in violation of law or (iv) violated in any material respect any provision of FCPA.

(ff)

Accountants. The Company’s accounting firm is set forth on Schedule 3.1(ff) of the Disclosure Schedules. To the knowledge

and belief of the Company, such accounting firm (i) is a registered public accounting firm as required by the Exchange Act and (ii) shall

express its opinion with respect to the financial statements to be included in the Company’s Annual Report for the fiscal year

end.

(gg)

Seniority. As of the Closing Date, no Indebtedness or other claim against the Company is senior to the Preferred Stock in right

of payment, whether with respect to interest or upon liquidation or dissolution, or otherwise, other than indebtedness secured by purchase

money security interests (which is senior only as to underlying assets covered thereby) and capital lease obligations (which is senior

only as to the property covered thereby). Notwithstanding the foregoing, the Company’s Series L 10% Convertible Preferred Stock

shall rank pari passu with the Preferred Stock in right of payment and with respect to interest or upon liquidation, dissolution and

winding up the Company.

(hh)

No Disagreements with Accountants and Lawyers. There are no disagreements of any kind presently existing, or reasonably anticipated

by the Company to arise, between the Company and the accountants and lawyers formerly or presently employed by the Company and the Company

is current with respect to any fees owed to its accountants and lawyers which could affect the Company’s ability to perform any

of its obligations under any of the Transaction Documents.

(ii)

Acknowledgment Regarding Purchasers’ Purchase of Securities. The Company acknowledges and agrees that each of the Purchasers

is acting solely in the capacity of an arm’s length purchaser with respect to the Transaction Documents and the transactions contemplated

thereby. The Company further acknowledges that no Purchaser is acting as a financial advisor or fiduciary of the Company (or in any similar

capacity) with respect to the Transaction Documents and the transactions contemplated thereby and any advice given by any Purchaser or

any of their respective representatives or agents in connection with the Transaction Documents and the transactions contemplated thereby

is merely incidental to the Purchasers’ purchase of the Securities. The Company further represents to each Purchaser that the Company’s

decision to enter into this Agreement and the other Transaction Documents has been based solely on the independent evaluation of the

transactions contemplated hereby by the Company and its representatives.

(jj)

Acknowledgment Regarding Purchaser’s Trading Activity. Anything in this Agreement or elsewhere herein to the contrary notwithstanding

(except for Sections 3.2(g) and 4.15 hereof), it is understood and acknowledged by the Company that: (i) none of the Purchasers has been

asked by the Company to agree, nor has any Purchaser agreed, to desist from purchasing or selling, long and/or short, securities of the

Company, or “derivative” securities based on securities issued by the Company or to hold the Securities for any specified

term, (ii) past or future open market or other transactions by any Purchaser, specifically including, without limitation, Short Sales

or “derivative” transactions, before or after the closing of this or future private placement transactions, may negatively

impact the market price of the Company’s publicly-traded securities, (iii) any Purchaser, and counter-parties in “derivative”

transactions to which any such Purchaser is a party, directly or indirectly, may presently have a “short” position in the

Common Stock and (iv) each Purchaser shall not be deemed to have any affiliation with or control over any arm’s length counter-party

in any “derivative” transaction. The Company further understands and acknowledges that (y) one or more Purchasers may engage

in hedging activities at various times during the period that the Securities are outstanding, including, without limitation, during the

periods that the value of the Underlying Shares deliverable with respect to Securities are being determined, and (z) such hedging activities

(if any) could reduce the value of the existing stockholders’ equity interests in the Company at and after the time that the hedging

activities are being conducted. The Company acknowledges that such aforementioned hedging activities do not constitute a breach of any

of the Transaction Documents.

18

(kk)

Regulation M Compliance. The Company has not, and to its knowledge no one acting on its behalf has, (i) taken, directly or indirectly,

any action designed to cause or to result in the stabilization or manipulation of the price of any security of the Company to facilitate

the sale or resale of any of the Securities, (ii) sold, bid for, purchased, or paid any compensation for soliciting purchases of, any

of the Securities, or (iii) paid or agreed to pay to any Person any compensation for soliciting another to purchase any other securities

of the Company, other than, in the case of clauses (ii) and (iii), compensation paid to any agent in connection with the placement of

the Securities.

(ll)

FDA. As to each product subject to the jurisdiction of the U.S. Food and Drug Administration (“FDA”) under

the Federal Food, Drug and Cosmetic Act, as amended, and the regulations thereunder (“FDCA”) that is manufactured,

packaged, labeled, tested, distributed, sold, and/or marketed by the Company or any of its Subsidiaries (each such product, a “Pharmaceutical

Product”), such Pharmaceutical Product is being manufactured, packaged, labeled, tested, distributed, sold and/or marketed

by the Company in compliance with all applicable requirements under FDCA and similar laws, rules and regulations relating to registration,

investigational use, premarket clearance, licensure, or application approval, good manufacturing practices, good laboratory practices,

good clinical practices, product listing, quotas, labeling, advertising, record keeping and filing of reports, except where the failure

to be in compliance would not have a Material Adverse Effect. There is no pending, completed or, to the Company’s knowledge, threatened,

action (including any lawsuit, arbitration, or legal or administrative or regulatory proceeding, charge, complaint, or investigation)

against the Company or any of its Subsidiaries, and none of the Company or any of its Subsidiaries has received any notice, warning letter

or other communication from the FDA or any other governmental entity, which (i) contests the premarket clearance, licensure, registration,

or approval of, the uses of, the distribution of, the manufacturing or packaging of, the testing of, the sale of, or the labeling and

promotion of any Pharmaceutical Product, (ii) withdraws its approval of, requests the recall, suspension, or seizure of, or withdraws

or orders the withdrawal of advertising or sales promotional materials relating to, any Pharmaceutical Product, (iii) imposes a clinical

hold on any clinical investigation by the Company or any of its Subsidiaries, (iv) enjoins production at any facility of the Company

or any of its Subsidiaries, (v) enters or proposes to enter into a consent decree of permanent injunction with the Company or any of

its Subsidiaries, or (vi) otherwise alleges any violation of any laws, rules or regulations by the Company or any of its Subsidiaries,

and which, either individually or in the aggregate, would have a Material Adverse Effect. The properties, business and operations of

the Company have been and are being conducted in all material respects in accordance with all applicable laws, rules and regulations

of the FDA. The Company has not been informed by the FDA that the FDA will prohibit the marketing, sale, license or use in the United

States of any product proposed to be developed, produced or marketed by the Company nor has the FDA expressed any concern as to approving

or clearing for marketing any product being developed or proposed to be developed by the Company.

(mm)

Stock Incentive Plans. Each stock incentive granted by the Company under any of the Company’s stock incentive plans was

granted (i) in accordance with the terms of the applicable stock incentive plan and (ii) with an exercise price at least equal to the

fair market value of the Common Stock on the date such stock incentive would be considered granted under GAAP and applicable law. No

stock option granted under any of the Company’s stock incentive plans has been backdated. The Company has not knowingly granted,

and there is no and has been no Company policy or practice to knowingly grant, stock options prior to, or otherwise knowingly coordinate

the grant of stock options with, the release or other public announcement of material information regarding the Company or its Subsidiaries

or their financial results or prospects.

19

(nn)

Cybersecurity. (i)(x) There has been no security breach or other compromise of or relating to any of the Company’s or any

Subsidiary’s information technology and computer systems, networks, hardware, software, data (including the data of its respective

customers, employees, suppliers, vendors and any third party data maintained by or on behalf of it), equipment or technology (collectively,

“IT Systems and Data”) and (y) the Company and the Subsidiaries have not been notified of, and have no knowledge of

any event or condition that would reasonably be expected to result in, any security breach or other compromise to their IT Systems and

Data; (ii) the Company and the Subsidiaries are presently in compliance with all applicable laws or statutes and all judgments, orders,

rules and regulations of any court or arbitrator or governmental or regulatory authority, internal policies and contractual obligations

relating to the privacy and security of IT Systems and Data and to the protection of such IT Systems and Data from unauthorized use,

access, misappropriation or modification, except as would not, individually or in the aggregate, have a Material Adverse Effect; (iii)

the Company and the Subsidiaries have implemented and maintained commercially reasonable safeguards to maintain and protect their material

confidential information and the integrity, continuous operation, redundancy and security of all IT Systems and Data; and (iv) the Company

and the Subsidiaries have implemented backup and disaster recovery technology consistent with industry standards and practices.

(oo)

Compliance with Data Privacy Laws. (i) The Company and the Subsidiaries are, and at all times during the last three (3) years

were, in compliance with all applicable state, federal and foreign data privacy and security laws and regulations, including, without

limitation, the European Union General Data Protection Regulation (“GDPR”) (EU 2016/679) (collectively, “Privacy

Laws”); (ii) the Company and the Subsidiaries have in place, comply with, and take appropriate steps reasonably designed to

ensure compliance with their policies and procedures relating to data privacy and security and the collection, storage, use, disclosure,

handling and analysis of Personal Data (as defined below) (the “Policies”); (iii) the Company provides accurate notice

of its applicable Policies to its customers, employees, third party vendors and representatives as required by the Privacy Laws; and

(iv) applicable Policies provide accurate and sufficient notice of the Company’s then-current privacy practices relating to its

subject matter, and do not contain any material omissions of the Company’s then-current privacy practices, as required by Privacy

Laws. “Personal Data” means (i) a natural person’s name, street address, telephone number, email address, photograph,

social security number, bank information, or customer or account number; (ii) any information which would qualify as “personally

identifying information” under the Federal Trade Commission Act, as amended; (iii) “personal data” as defined by GDPR;

and (iv) any other piece of information that allows the identification of such natural person, or his or her family, or permits the collection

or analysis of any identifiable data related to an identified person’s health or sexual orientation. (i) None of such disclosures

made or contained in any of the Policies have been inaccurate, misleading, or deceptive in violation of any Privacy Laws and (ii) the

execution, delivery and performance of the Transaction Documents will not result in a breach of any Privacy Laws or Policies. Neither

the Company nor the Subsidiaries (A) to the knowledge of the Company, has received written notice of any actual or potential liability

of the Company or the Subsidiaries under, or actual or potential violation by the Company or the Subsidiaries of, any of the Privacy

Laws; (B) is currently conducting or paying for, in whole or in part, any investigation, remediation or other corrective action pursuant

to any regulatory request or demand pursuant to any Privacy Law; or (C) is a party to any order, decree, or agreement by or with any

court or arbitrator or governmental or regulatory authority that imposed any obligation or liability under any Privacy Law.

(pp)

Office of Foreign Assets Control. Neither the Company nor any Subsidiary nor, to the Company’s knowledge, any director,

officer, agent, employee or affiliate of the Company or any Subsidiary is currently subject to any U.S. sanctions administered by the

Office of Foreign Assets Control of the U.S. Treasury Department (“OFAC”).

(qq)

U.S. Real Property Holding Corporation. The Company is not and has never been a U.S. real property holding corporation within

the meaning of Section 897 of the Internal Revenue Code of 1986, as amended, and the Company shall so certify upon Purchaser’s

request.

20

(rr)

Bank Holding Company Act. Neither the Company nor any of its Subsidiaries or Affiliates is subject to the Bank Holding Company

Act of 1956, as amended (the “BHCA”) and to regulation by the Board of Governors of the Federal Reserve System (the

“Federal Reserve”). Neither the Company nor any of its Subsidiaries or Affiliates owns or controls, directly or indirectly,

five percent (5%) or more of the outstanding shares of any class of voting securities or twenty-five percent or more of the total equity

of a bank or any entity that is subject to the BHCA and to regulation by the Federal Reserve. Neither the Company nor any of its Subsidiaries

or Affiliates exercises a controlling influence over the management or policies of a bank or any entity that is subject to the BHCA and

to regulation by the Federal Reserve.

(ss)

Money Laundering. The operations of the Company and its Subsidiaries are and have been conducted at all times in compliance with

applicable financial record-keeping and reporting requirements of the Currency and Foreign Transactions Reporting Act of 1970, as amended,

applicable money laundering statutes and applicable rules and regulations thereunder (collectively, the “Money Laundering Laws”),

and no Action or Proceeding by or before any court or governmental agency, authority or body or any arbitrator involving the Company

or any Subsidiary with respect to the Money Laundering Laws is pending or, to the knowledge of the Company or any Subsidiary, threatened.

(tt)

No Disqualification Events. With respect to the Securities to be offered and sold hereunder in reliance on Rule 506 under the

Securities Act, none of the Company, any of its predecessors, any affiliated issuer, any director, executive officer, other officer of

the Company participating in the offering hereunder, any beneficial owner of 20% or more of the Company’s outstanding voting equity

securities, calculated on the basis of voting power, nor any promoter (as that term is defined in Rule 405 under the Securities Act)

connected with the Company in any capacity at the time of sale (each, an “Issuer Covered Person” and, together, “Issuer

Covered Persons”) is subject to any of the “Bad Actor” disqualifications described in Rule 506(d)(1)(i) to (viii)

under the Securities Act (a “Disqualification Event”), except for a Disqualification Event covered by Rule 506(d)(2)

or (d)(3). The Company has exercised reasonable care to determine whether any Issuer Covered Person is subject to a Disqualification

Event. The Company has complied, to the extent applicable, with its disclosure obligations under Rule 506(e), and has furnished to the

Purchasers a copy of any disclosures provided thereunder.

(uu)

Other Covered Persons. The Company is not aware of any person (other than any Issuer Covered Person) that has been or will be

paid (directly or indirectly) remuneration for solicitation of purchasers in connection with the sale of any Securities.

(vv)

Notice of Disqualification Events. The Company will notify the Purchasers in writing, prior to the Closing Date of (i) any Disqualification

Event relating to any Issuer Covered Person and (ii) any event that would, with the passage of time, become a Disqualification Event

relating to any Issuer Covered Person.

3.2

Representations and Warranties of the Purchasers. Each Purchaser, for itself and for no other Purchaser, hereby represents and

warrants as of the date hereof and as of the Closing Date to the Company as follows (unless as of a specific date therein, in which case

they shall be accurate as of such date):

(a)

Organization; Authority. Such Purchaser is either an individual or an entity duly incorporated or formed, validly existing and

in good standing under the laws of the jurisdiction of its incorporation or formation with full right, corporate, partnership, limited

liability company or similar power and authority to enter into and to consummate the transactions contemplated by the Transaction Documents

and otherwise to carry out its obligations hereunder and thereunder. The execution and delivery of the Transaction Documents and performance

by such Purchaser of the transactions contemplated by the Transaction Documents have been duly authorized by all necessary corporate,

partnership, limited liability company or similar action, as applicable, on the part of such Purchaser. Each Transaction Document to

which it is a party has been duly executed by such Purchaser, and when delivered by such Purchaser in accordance with the terms hereof,

will constitute the valid and legally binding obligation of such Purchaser, enforceable against it in accordance with its terms, except

(i) as limited by general equitable principles and applicable bankruptcy, insolvency, reorganization, moratorium and other laws of general

application affecting enforcement of creditors’ rights generally, (ii) as limited by laws relating to the availability of specific

performance, injunctive relief or other equitable remedies and (iii) insofar as indemnification and contribution provisions may be limited

by applicable law.

21

(b)

Own Account. Such Purchaser understands that the Securities are “restricted securities” and have not been registered

under the Securities Act or any applicable state securities law and is acquiring the Securities as principal for its own account and

not with a view to or for distributing or reselling such Securities or any part thereof in violation of the Securities Act or any applicable

state securities law, has no present intention of distributing any of such Securities in violation of the Securities Act or any applicable

state securities law and has no direct or indirect arrangement or understandings with any other persons to distribute or regarding the

distribution of such Securities in violation of the Securities Act or any applicable state securities law (this representation and warranty

not limiting such Purchaser’s right to sell the Securities pursuant to the Registration Statement or otherwise in compliance with

applicable federal and state securities laws). Such Purchaser is acquiring the Securities hereunder in the ordinary course of its business.

(c)

Purchaser Status. At the time such Purchaser was offered the Securities, it was, and as of the date hereof it is, and on each

date on which it exercises any Warrants or converts any shares of Preferred Stock, it will be an “accredited investor” as

defined in Rule 501(a)(1), (a)(2), (a)(3), (a)(7), (a)(8), (a)(9), (a)(12), or (a)(13) under the Securities Act. The information set

forth on the signature page hereto regarding such Purchaser is true and complete in all respects.

(d)

Experience of Such Purchaser. Such Purchaser, either alone or together with its representatives, has such knowledge, sophistication

and experience in business and financial matters so as to be capable of evaluating the merits and risks of the prospective investment

in the Securities, and has so evaluated the merits and risks of such investment. Such Purchaser is able to bear the economic risk of

an investment in the Securities and, at the present time, is able to afford a complete loss of such investment.

(e)

General Solicitation. Such Purchaser is not, to such Purchaser’s knowledge, purchasing the Securities as a result of any

advertisement, article, notice or other communication regarding the Securities published in any newspaper, magazine or similar media

or broadcast over television or radio or presented at any seminar or, to the knowledge of such Purchaser, any other general solicitation

or general advertisement.

(f)

Access to Information. Such Purchaser acknowledges that it has had the opportunity to review the Transaction Documents (including

all exhibits and schedules thereto) and the SEC Reports and has been afforded (i) the opportunity to ask such questions as it has deemed

necessary of, and to receive answers from, representatives of the Company concerning the terms and conditions of the offering of the

Securities and the merits and risks of investing in the Securities; (ii) access to information about the Company and its financial condition,

results of operations, business, properties, management and prospects sufficient to enable it to evaluate its investment; and (iii) the

opportunity to obtain such additional information that the Company possesses or can acquire without unreasonable effort or expense that

is necessary to make an informed investment decision with respect to the investment.

(g)

Certain Transactions and Confidentiality. Other than consummating the transactions contemplated hereunder, such Purchaser has

not, nor has any Person acting on behalf of or pursuant to any understanding with such Purchaser, directly or indirectly executed any

purchases or sales, including Short Sales, of the securities of the Company during the period commencing as of the time that such Purchaser

first received a term sheet (written or oral) from the Company or any other Person representing the Company setting forth the material

terms of the transactions contemplated hereunder and ending immediately prior to the execution hereof. Notwithstanding the foregoing,

in the case of a Purchaser that is a multi-managed investment vehicle whereby separate portfolio managers manage separate portions of

such Purchaser’s assets and the portfolio managers have no direct knowledge of the investment decisions made by the portfolio managers

managing other portions of such Purchaser’s assets, the representation set forth above shall only apply with respect to the portion

of assets managed by the portfolio manager that made the investment decision to purchase the Securities covered by this Agreement. Other

than to other Persons party to this Agreement or to such Purchaser’s representatives, including, without limitation, its officers,

directors, partners, legal and other advisors, employees, agents and Affiliates, such Purchaser has maintained the confidentiality of

all disclosures made to it in connection with this transaction (including the existence and terms of this transaction). Notwithstanding

the foregoing, for the avoidance of doubt, nothing contained herein shall constitute a representation or warranty, or preclude any actions,

with respect to locating or borrowing shares in order to effect Short Sales or similar transactions in the future.

22

The

Company acknowledges and agrees that the representations contained in this Section 3.2 shall not modify, amend or affect such Purchaser’s

right to rely on the Company’s representations and warranties contained in this Agreement or any representations and warranties

contained in any other Transaction Document or any other document or instrument executed and/or delivered in connection with this Agreement

or the consummation of the transactions contemplated hereby. Notwithstanding the foregoing, for the avoidance of doubt, nothing contained

herein shall constitute a representation or warranty, or preclude any actions, with respect to locating or borrowing shares in order

to effect Short Sales or similar transactions in the future.

ARTICLE

IV.

OTHER

AGREEMENTS OF THE PARTIES

4.1

Transfer Restrictions.

(a)

The Securities may only be disposed of in compliance with state and federal securities laws. In connection with any transfer of Securities

other than pursuant to an effective registration statement or Rule 144, to the Company or to an Affiliate of a Purchaser or in connection

with a pledge as contemplated in Section 4.1(b), the Company may require the transferor thereof to provide to the Company an opinion

of counsel selected by the transferor and reasonably acceptable to the Company, the form and substance of which opinion shall be reasonably

satisfactory to the Company, to the effect that such transfer does not require registration of such transferred Securities under the

Securities Act. As a condition of transfer, any such transferee shall agree in writing to be bound by the terms of this Agreement and

the Registration Rights Agreement and shall have the rights and obligations of a Purchaser under this Agreement and the Registration

Rights Agreement.

(b)

The Purchasers agree to the imprinting, so long as is required by this Section 4.1, of a legend on any of the Securities in the following

form:

[NEITHER]

THIS SECURITY [NOR THE SECURITIES INTO WHICH THIS SECURITY IS [EXERCISABLE] [CONVERTIBLE]] HAS [NOT] BEEN REGISTERED WITH THE SECURITIES

AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES

ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION

REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS. THIS SECURITY [AND THE SECURITIES ISSUABLE

UPON [EXERCISE] [CONVERSION] OF THIS SECURITY] MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT WITH A REGISTERED BROKER-DEALER

OR OTHER LOAN WITH A FINANCIAL INSTITUTION THAT IS AN “ACCREDITED INVESTOR” AS DEFINED IN RULE 501(a) UNDER THE SECURITIES

ACT OR OTHER LOAN SECURED BY SUCH SECURITIES.

23

The

Company acknowledges and agrees that a Purchaser may from time to time pledge pursuant to a bona fide margin agreement with a registered

broker-dealer or grant a security interest in some or all of the Securities to a financial institution that is an “accredited investor”

as defined in Rule 501(a) under the Securities Act and, if required under the terms of such arrangement, such Purchaser may transfer

pledged or secured Securities to the pledgees or secured parties. Such a pledge or transfer would not be subject to approval of the Company

and no legal opinion of legal counsel of the pledgee, secured party or pledgor shall be required in connection therewith. Further, no

notice shall be required of such pledge. At the appropriate Purchaser’s expense, the Company will execute and deliver such reasonable

documentation as a pledgee or secured party of Securities may reasonably request in connection with a pledge or transfer of the Securities,

including, if the Securities are subject to registration pursuant to the Registration Rights Agreement, the preparation and filing of

any required prospectus supplement under Rule 424(b)(3) under the Securities Act or other applicable provision of the Securities Act

to appropriately amend the list of Selling Stockholders (as defined in the Registration Rights Agreement) thereunder.

(c)

Certificates evidencing the Underlying Shares shall not contain any legend (including the legend set forth in Section 4.1(b) hereof):

(i) while a registration statement (including the Registration Statement) covering the resale of such security is effective under the

Securities Act, (ii) following any sale of such Underlying Shares pursuant to Rule 144 (assuming cashless exercise of the Warrants),

(iii) if such Underlying Shares are eligible for sale under Rule 144 (assuming cashless exercise of the Warrants), without the requirement

for the Company to be in compliance with the current public information required under Rule 144 as to such Underlying Shares and without

volume or manner-of-sale restrictions or (iv) if such legend is not required under applicable requirements of the Securities Act (including

judicial interpretations and pronouncements issued by the staff of the Commission). The Company shall cause its counsel to issue a legal

opinion to the Transfer Agent or the Purchaser promptly after the Effective Date if required by the Transfer Agent to effect the removal

of the legend hereunder, or if requested by a Purchaser, respectively. If all or any shares of Preferred Stock are converted or any portion

of a Warrant is exercised at a time when there is an effective registration statement to cover the resale of the Underlying Shares, or

if such Underlying Shares may be sold under Rule 144 and the Company is then in compliance with the current public information required

under Rule 144, or if the Underlying Shares may be sold under Rule 144 (assuming cashless exercise of the Warrants) without the requirement

for the Company to be in compliance with the current public information required under Rule 144 as to such Underlying Shares and without

volume or manner-of-sale restrictions or if such legend is not otherwise required under applicable requirements of the Securities Act

(including judicial interpretations and pronouncements issued by the staff of the Commission) then such Underlying Shares shall be issued

free of all legends. The Company agrees that following the Effective Date or at such time as such legend is no longer required under

this Section 4.1(c), it will, no later than the earlier of (i) two (2) Trading Days and (ii) the number of Trading Days comprising the

Standard Settlement Period (as defined below) following the delivery by a Purchaser to the Company or the Transfer Agent of a certificate

representing Underlying Shares, as applicable, issued with a restrictive legend (such date, the “Legend Removal Date”),

deliver or cause to be delivered to such Purchaser a certificate representing such shares that is free from all restrictive and other

legends. The Company may not make any notation on its records or give instructions to the Transfer Agent that enlarge the restrictions

on transfer set forth in this Section 4. Certificates for Underlying Shares subject to legend removal hereunder shall be transmitted

by the Transfer Agent to the Purchaser by crediting the account of the Purchaser’s prime broker with the Depository Trust Company

System as directed by such Purchaser. As used herein, “Standard Settlement Period” means the standard settlement period,

expressed in a number of Trading Days, on the Company’s primary Trading Market with respect to the Common Stock as in effect on

the date of delivery of a certificate representing Underlying Shares, as applicable, issued with a restrictive legend.

(d)

In addition to such Purchaser’s other available remedies, the Company shall pay to a Purchaser, in cash, (i) as partial liquidated

damages and not as a penalty, for each $1,000 of Underlying Shares (based on the VWAP of the Common Stock on the date such Securities

are submitted to the Transfer Agent) delivered for removal of the restrictive legend and subject to Section 4.1(c), $10 per Trading Day

(increasing to $20 per Trading Day five (5) Trading Days after the Legend Removal Date) for each Trading Day after the Legend Removal

Date until such certificate is delivered without a legend and (ii) if the Company fails to (a) issue and deliver (or cause to be delivered)

to a Purchaser by the Legend Removal Date a certificate representing the Securities so delivered to the Company by such Purchaser that

is free from all restrictive and other legends and (b) if after the Legend Removal Date such Purchaser purchases (in an open market transaction

or otherwise) shares of Common Stock to deliver in satisfaction of a sale by such Purchaser of all or any portion of the number of shares

of Common Stock, or a sale of a number of shares of Common Stock equal to all or any portion of the number of shares of Common Stock

that such Purchaser anticipated receiving from the Company without any restrictive legend, then, an amount equal to the excess of such

Purchaser’s total purchase price (including brokerage commissions and other out-of-pocket expenses, if any) for the shares of Common

Stock so purchased (including brokerage commissions and other out-of-pocket expenses, if any) (the “Buy-In Price”)

over the product of (x) such number of Underlying Shares that the Company was required to deliver to such Purchaser by the Legend Removal

Date multiplied by (y) the lowest closing sale price of the Common Stock on any Trading Day during the period commencing on the date

of the delivery by such Purchaser to the Company of the applicable Underlying Shares (as the case may be) and ending on the date of such

delivery and payment under this clause (ii).

24

(e)

Each Purchaser, severally and not jointly with the other Purchasers, agrees with the Company that such Purchaser will sell any Securities

pursuant to either the registration requirements of the Securities Act, including any applicable prospectus delivery requirements, or

an exemption therefrom, and that if Securities are sold pursuant to a Registration Statement, they will be sold in compliance with the

plan of distribution set forth therein, and acknowledges that the removal of the restrictive legend from certificates representing Securities

as set forth in this Section 4.1 is predicated upon the Company’s reliance upon this understanding.

4.2

Acknowledgment of Dilution. The Company acknowledges that the issuance of the Securities may result in dilution of the outstanding

shares of Common Stock, which dilution may be substantial under certain market conditions. The Company further acknowledges that its

obligations under the Transaction Documents, including, without limitation, its obligation to issue the Underlying Shares pursuant to

the Transaction Documents, are unconditional and absolute and not subject to any right of set off, counterclaim, delay or reduction,

regardless of the effect of any such dilution or any claim the Company may have against any Purchaser and regardless of the dilutive

effect that such issuance may have on the ownership of the other stockholders of the Company.

4.3

Furnishing of Information; Public Information.

(a)

Until the earlier of the time that (i) no Purchaser owns Securities or (ii) the Warrants have expired, the Company covenants to maintain

the registration of the Common Stock under Section 12(b) or 12(g) of the Exchange Act and to timely file (or obtain extensions in respect

thereof and file within the applicable grace period) all reports required to be filed by the Company after the date hereof pursuant to

the Exchange Act even if the Company is not then subject to the reporting requirements of the Exchange Act.

(b)

At any time during the period commencing from the six (6) month anniversary of the date hereof and ending at such time that all of the

Securities may be sold without the requirement for the Company to be in compliance with Rule 144(c)(1) and otherwise without restriction

or limitation pursuant to Rule 144, if the Company (i) shall fail for any reason to satisfy the current public information requirement

under Rule 144(c) or (ii) has ever been an issuer described in Rule 144(i)(1)(i) or becomes an issuer in the future, and the Company

shall fail to satisfy any condition set forth in Rule 144(i)(2) (a “Public Information Failure”) then, in addition

to such Purchaser’s other available remedies, the Company shall pay to a Purchaser, in cash, as partial liquidated damages and

not as a penalty, by reason of any such delay in or reduction of its ability to sell the Securities, an amount in cash equal to one percent

(1.0%) of the aggregate Subscription Amount of such Purchaser’s Securities on the day of a Public Information Failure and on every

thirtieth (30th) day (pro rated for periods totaling less than thirty days) thereafter until the earlier of (a) the date such

Public Information Failure is cured and (b) such time that such public information is no longer required for the Purchasers to transfer

the Underlying Shares pursuant to Rule 144. The payments to which a Purchaser shall be entitled pursuant to this Section 4.3(b) are referred

to herein as “Public Information Failure Payments.” Public Information Failure Payments shall be paid on the earlier

of (i) the last day of the calendar month during which such Public Information Failure Payments are incurred and (ii) the third (3rd)

Business Day after the event or failure giving rise to the Public Information Failure Payments is cured. In the event the Company fails

to make Public Information Failure Payments in a timely manner, such Public Information Failure Payments shall bear interest at the rate

of 1.5% per month (prorated for partial months) until paid in full. Nothing herein shall limit such Purchaser’s right to pursue

actual damages for the Public Information Failure, and such Purchaser shall have the right to pursue all remedies available to it at

law or in equity including, without limitation, a decree of specific performance and/or injunctive relief.

25

4.4

Integration. The Company shall not sell, offer for sale or solicit offers to buy or otherwise negotiate in respect of any security

(as defined in Section 2 of the Securities Act) that would be integrated with the offer or sale of the Securities in a manner that would

require the registration under the Securities Act of the sale of the Securities or that would be integrated with the offer or sale of

the Securities for purposes of the rules and regulations of any Trading Market such that it would require shareholder approval prior

to the closing of such other transaction unless shareholder approval is obtained before the closing of such subsequent transaction.

4.5

Conversion and Exercise Procedures. Each of the form of Notice of Exercise included in the Warrants and the form of Notice of

Conversion included in the Certificate of Designation set forth the totality of the procedures required of the Purchasers in order to

exercise the Warrants or convert the Preferred Stock. Without limiting the preceding sentences, no ink-original Notice of Exercise or

Notice of Conversion shall be required, nor shall any medallion guarantee (or other type of guarantee or notarization) of any Notice

of Exercise or Notice of Conversion form be required in order to exercise the Warrants or convert the Preferred Stock. No additional

legal opinion, other information or instructions shall be required of the Purchasers to exercise their Warrants or convert their Preferred

Stock. The Company shall honor exercises of the Warrants and conversions of the Preferred Stock and shall deliver Underlying Shares in

accordance with the terms, conditions and time periods set forth in the Transaction Documents.

4.6

Securities Laws Disclosure; Publicity. The Company shall by each of (a) the Disclosure Time and (b) the exercise of any Greenshoe

Right pursuant to Section 2.4, file a Current Report on Form 8-K (or, in the case of Greenshoe Rights, a press release), including the

Transaction Documents as exhibits thereto, with the Commission disclosing the material terms of the transactions contemplated hereby.

From and after the filing of each such Current Report on Form 8-K (or, as applicable, press release), the Company represents to the Purchasers

that it shall have publicly disclosed all material, non-public information delivered to any of the Purchasers by the Company or any of

its Subsidiaries, or any of their respective officers, directors, employees, Affiliates or agents, in connection with the transactions

contemplated by the Transaction Documents. In addition, effective upon the filing of each such Current Report on Form 8-K (or, as applicable,

a press release), the Company acknowledges and agrees that any and all confidentiality or similar obligations under any agreement, whether

written or oral, between the Company, any of its Subsidiaries or any of their respective officers, directors, agents, employees, Affiliates

or agents, on the one hand, and any of the Purchasers or any of their Affiliates on the other hand, shall terminate and be of no further

force or effect. The Company understands and confirms that each Purchaser shall be relying on the foregoing covenant in effecting transactions

in securities of the Company. The Company and each Purchaser shall consult with each other in issuing any press releases with respect

to the transactions contemplated hereby, and neither the Company nor any Purchaser shall issue any such press release nor otherwise make

any such public statement without the prior consent of the Company, with respect to any press release of any Purchaser, or without the

prior consent of each Purchaser, with respect to any press release of the Company, which consent shall not unreasonably be withheld or

delayed, except if such disclosure is required by law, in which case the disclosing party shall promptly provide the other party with

prior notice of such public statement or communication. Notwithstanding the foregoing, the Company shall not publicly disclose the name

of any Purchaser, or include the name of any Purchaser in any filing with the Commission or any regulatory agency or Trading Market,

without the prior written consent of such Purchaser, except (a) as required by federal securities law in connection with (i) any registration

statement contemplated by the Registration Rights Agreement and (ii) the filing of final Transaction Documents with the Commission and

(b) to the extent such disclosure is required by law or Trading Market regulations, in which case the Company shall provide the Purchasers

with prior notice of such disclosure permitted under this clause (b) and reasonably cooperate with such Purchaser regarding such disclosure.

26

4.7

Shareholder Rights Plan. No claim will be made or enforced by the Company or, with the consent of the Company, any other Person,

that any Purchaser is an “Acquiring Person” under any control share acquisition, business combination, poison pill

(including any distribution under a rights agreement) or similar anti-takeover plan or arrangement in effect or hereafter adopted by

the Company, or that any Purchaser could be deemed to trigger the provisions of any such plan or arrangement, by virtue of receiving

Securities under the Transaction Documents or under any other agreement between the Company and the Purchasers.

4.8

Non-Public Information. Except with respect to the material terms and conditions of the transactions contemplated by the Transaction

Documents, which shall be disclosed pursuant to Section 4.6, the Company covenants and agrees that neither it, nor any other Person acting

on its behalf will provide any Purchaser or its agents or counsel with any information that constitutes, or the Company reasonably believes

constitutes, material non-public information, unless prior thereto such Purchaser shall have consented in writing to the receipt of such

information and agreed in writing with the Company to keep such information confidential. The Company understands and confirms that each

Purchaser shall be relying on the foregoing covenant in effecting transactions in securities of the Company. To the extent that the Company,

any of its Subsidiaries, or any of their respective officers, directors, agents, employees or Affiliates delivers any material, non-public

information to a Purchaser without such Purchaser’s consent, the Company hereby covenants and agrees that such Purchaser shall

not have any duty of confidentiality to the Company, any of its Subsidiaries, or any of their respective officers, directors, employees,

Affiliates or agents, or a duty to the Company, any of its Subsidiaries or any of their respective officers, directors, employees, Affiliates

or agents, not to trade on the basis of, such material, non-public information, provided that the Purchaser shall remain subject to applicable

law. To the extent that any notice provided pursuant to any Transaction Document constitutes, or contains, material, non-public information

regarding the Company or any Subsidiaries, the Company shall simultaneously with the delivery of such notice file such notice with the

Commission pursuant to a Current Report on Form 8-K. The Company understands and confirms that each Purchaser shall be relying on the

foregoing covenant in effecting transactions in securities of the Company.

4.9

Use of Proceeds. The Company shall use the net proceeds from the sale of the Securities hereunder for working capital purposes

and shall not use such proceeds: (a) for the satisfaction of any portion of the Company’s debt (other than payment of trade payables

in the ordinary course of the Company’s business and prior practices), (b) for the redemption of any Common Stock or Common Stock

Equivalents, (c) for the settlement of any outstanding litigation or (d) in violation of FCPA or OFAC regulations.

4.10

Indemnification of Purchasers. Subject to the provisions of this Section 4.10, the Company will indemnify and hold each Purchaser

and its directors, officers, shareholders, members, partners, employees and agents (and any other Persons with a functionally equivalent

role of a Person holding such titles notwithstanding a lack of such title or any other title), each Person who controls such Purchaser

(within the meaning of Section 15 of the Securities Act and Section 20 of the Exchange Act), and the directors, officers, shareholders,

agents, members, partners or employees (and any other Persons with a functionally equivalent role of a Person holding such titles notwithstanding

a lack of such title or any other title) of such controlling persons (each, a “Purchaser Party”) harmless from any

and all losses, liabilities, obligations, claims, contingencies, damages, costs and reasonable expenses, including all judgments, amounts

paid in settlements, court costs and reasonable attorneys’ fees and costs of investigation that any such Purchaser Party may suffer

or incur as a result of or relating to (a) any breach of any of the representations, warranties, covenants or agreements made by the

Company in this Agreement or in the other Transaction Documents or (b) any action instituted against the Purchaser Parties in any capacity,

or any of them or their respective Affiliates, by any stockholder of the Company who is not an Affiliate of such Purchaser Party, with

respect to any of the transactions contemplated by the Transaction Documents (unless such action is solely based upon a material breach

of such Purchaser Party’s representations, warranties or covenants under the Transaction Documents or any agreements or understandings

such Purchaser Party may have with any such stockholder or any violations by such Purchaser Party of state or federal securities laws

or any conduct by such Purchaser Party which is finally judicially determined to constitute fraud, gross negligence or willful misconduct.

If any action shall be brought against any Purchaser Party in respect of which indemnity may be sought pursuant to this Agreement, such

Purchaser Party shall promptly notify the Company in writing, and, the Company shall have the right to assume the defense thereof with

counsel of its own choosing reasonably acceptable to the Purchaser Party. Any Purchaser Party shall have the right to employ separate

counsel in any such action and participate in the defense thereof, but the fees and expenses of such counsel shall be at the expense

of such Purchaser Party except to the extent that (i) the employment thereof has been specifically authorized by the Company in writing,

(ii) the Company has failed after a reasonable period of time to assume such defense and to employ counsel or (iii) in such action there

is, in the reasonable opinion of counsel a material conflict on any material issue between the position of the Company and the position

of such Purchaser Party, in which case the Company shall be responsible for the reasonable fees and expenses of no more than one such

separate counsel. The Company will not be liable to any Purchaser Party under this Agreement (y) for any settlement by a Purchaser Party

effected without the Company’s prior written consent, which shall not be unreasonably withheld or delayed; or (z) to the extent,

but only to the extent that a loss, claim, damage or liability is attributable to any Purchaser Party’s breach of any of the representations,

warranties, covenants or agreements made by such Purchaser Party in the Transaction Documents. The indemnification required by this Section

4.10 shall be made by periodic payments of the amount thereof during the course of the investigation or defense, as and when bills are

received or are incurred. The indemnity agreements contained herein shall be in addition to any cause of action or similar right of any

Purchaser Party against the Company or others and any liabilities the Company may be subject to pursuant to law.

27

4.11

Reservation and Listing of Securities.

(a)

The Company shall maintain a reserve of the Required Minimum from its duly authorized shares of Common Stock for issuance pursuant to

the Transaction Documents in such amount as may then be required to fulfill its obligations in full under the Transaction Documents.

(b)

If, on any date, the number of authorized but unissued (and otherwise unreserved) shares of Common Stock is less than (i) the Required

Minimum on such date, minus (ii) the number of shares of Common Stock previously issued pursuant to the Transaction Documents, then the

Board of Directors shall use commercially reasonable efforts to amend the Company’s certificate of incorporation to increase the

number of authorized but unissued shares of Common Stock to at least the Required Minimum at such time (minus the number of shares of

Common Stock previously issued pursuant to the Transaction Documents), as soon as possible and in any event not later than the 75th

day after such date, provided that the Company will not be required at any time to authorize a number of shares of Common Stock greater

than the maximum remaining number of shares of Common Stock that could possibly be issued after such time pursuant to the Transaction

Documents.

(c)

The Company shall, if applicable: (i) in the time and manner required by the principal Trading Market, prepare and file with such Trading

Market an additional shares listing application covering a number of shares of Common Stock at least equal to the Required Minimum on

the date of such application, (ii) take all steps necessary to cause such shares of Common Stock to be approved for listing or quotation

on such Trading Market as soon as possible thereafter, (iii) provide to the Purchasers evidence of such listing or quotation and (iv)

maintain the listing or quotation of such Common Stock on any date at least equal to the Required Minimum on such date on such Trading

Market or another Trading Market. The Company agrees to maintain the eligibility of the Common Stock for electronic transfer through

the Depository Trust Company or another established clearing corporation, including, without limitation, by timely payment of fees to

the Depository Trust Company or such other established clearing corporation in connection with such electronic transfer.

(d)

In addition, the Company shall hold a special meeting of shareholders (which may also be at the annual meeting of shareholders) at the

earliest practical date after the date hereof for the purpose of obtaining Shareholder Approval, with the recommendation of the Company’s

Board of Directors that such proposal or proposals be approved, and the Company shall solicit proxies from its shareholders in connection

therewith in the same manner as all other management proposals in such proxy statement and all management-appointed proxyholders shall

vote their proxies in favor of such proposal or proposals. The Company shall use commercially reasonable efforts to obtain such Shareholder

Approval. If the Company does not obtain Shareholder Approval at the first meeting, the Company shall call a meeting every four months

thereafter to seek Shareholder Approval until the earlier of the date Shareholder Approval is obtained or the Preferred Stock is no longer

outstanding.

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4.12

Participation in Future Financing.

(a)

From the date hereof until the date that is the 18-month anniversary of the Effective Date, upon any issuance by the Company or any of

its Subsidiaries of Common Stock or Common Stock Equivalents for cash consideration, Indebtedness or a combination of units thereof (a

“Subsequent Financing”), each Purchaser shall have the right to participate in up to an amount of the Subsequent Financing

equal to 100% of the Subsequent Financing (the “Participation Maximum”) on the same terms, conditions and price provided

for in the Subsequent Financing.

(b)

At least five (5) Trading Days prior to the closing of the Subsequent Financing, the Company shall deliver to each Purchaser a written

notice of its intention to effect a Subsequent Financing (“Pre-Notice”), which Pre-Notice shall ask such Purchaser

if it wants to review the details of such financing (such additional notice, a “Subsequent Financing Notice”). Upon

the request of a Purchaser, and only upon a request by such Purchaser, for a Subsequent Financing Notice, the Company shall promptly,

but no later than one (1) Trading Day after such request, deliver a Subsequent Financing Notice to such Purchaser. The Subsequent Financing

Notice shall describe in reasonable detail the proposed terms of such Subsequent Financing, the amount of proceeds intended to be raised

thereunder and the Person or Persons through or with whom such Subsequent Financing is proposed to be effected and shall include a term

sheet or similar document relating thereto as an attachment.

(c)

Any Purchaser desiring to participate in such Subsequent Financing must provide written notice to the Company by not later than 5:30

p.m. (New York City time) on the fifth (5th) Trading Day after all of the Purchasers have received the Pre-Notice that such

Purchaser is willing to participate in the Subsequent Financing, the amount of such Purchaser’s participation, and representing

and warranting that such Purchaser has such funds ready, willing, and available for investment on the terms set forth in the Subsequent

Financing Notice. If the Company receives no such notice from a Purchaser as of such fifth (5th) Trading Day, such Purchaser

shall be deemed to have notified the Company that it does not elect to participate.

(d)

If by 5:30 p.m. (New York City time) on the fifth (5th) Trading Day after all of the Purchasers have received the Pre-Notice,

notifications by the Purchasers of their willingness to participate in the Subsequent Financing (or to cause their designees to participate)

is, in the aggregate, less than the total amount of the Subsequent Financing, then the Company may effect the remaining portion of such

Subsequent Financing on the terms and with the Persons set forth in the Subsequent Financing Notice.

(e)

If by 5:30 p.m. (New York City time) on the fifth (5th) Trading Day after all of the Purchasers have received the Pre-Notice,

the Company receives responses to a Subsequent Financing Notice from Purchasers seeking to purchase more than the aggregate amount of

the Participation Maximum, each such Purchaser shall have the right to purchase its Pro Rata Portion (as defined below) of the Participation

Maximum. “Pro Rata Portion” means the ratio of (x) the Subscription Amount of Securities purchased on the Closing

Date by a Purchaser participating under this Section 4.12 and (y) the sum of the aggregate Subscription Amounts of Securities purchased

on the Closing Date by all Purchasers participating under this Section 4.12 plus the aggregate subscription amounts of investors party

to securities purchase agreement(s) contemplated by clause (d) in the definition of Exempt Issuance that are participating in such Subsequent

Financing pursuant to participation rights granted to such investors under such agreements that are substantially similar to this Section

4.12.

29

(f)

The Company must provide the Purchasers with a second Subsequent Financing Notice, and the Purchasers will again have the right of participation

set forth above in this Section 4.12, if the Subsequent Financing subject to the initial Subsequent Financing Notice is not consummated

for any reason on the terms set forth in such Subsequent Financing Notice within thirty (30) Trading Days after the date of the initial

Subsequent Financing Notice.

(g)

The Company and each Purchaser agree that if any Purchaser elects to participate in the Subsequent Financing, the transaction documents

related to the Subsequent Financing shall not include any term or provision that, directly or indirectly, will, or is intended to, exclude

one or more of the Purchasers from participating in a Subsequent Financing, including, but not limited to, provisions whereby such Purchaser

shall be required to agree to any restrictions on trading as to any securities of the Company or be required to consent to any amendment

to or termination of, or grant any waiver, release or the like under or in connection with, this Agreement, without the prior written

consent of such Purchaser.

(h)

Notwithstanding anything to the contrary in this Section 4.12 and unless otherwise agreed to by such Purchaser, the Company shall either

confirm in writing to such Purchaser that the transaction with respect to the Subsequent Financing has been abandoned or shall publicly

disclose its intention to issue the securities in the Subsequent Financing, in either case in such a manner such that such Purchaser

will not be in possession of any material, non-public information, by the tenth (10th) Business Day following delivery of the Subsequent

Financing Notice. If by such tenth (10th) Business Day, no public disclosure regarding a transaction with respect to the Subsequent Financing

has been made, and no notice regarding the abandonment of such transaction has been received by such Purchaser, such transaction shall

be deemed to have been abandoned and such Purchaser shall not be deemed to be in possession of any material, non-public information with

respect to the Company or any of its Subsidiaries.

(i)

Notwithstanding the foregoing, this Section 4.12 shall not apply in respect of (i) an Exempt Issuance and (ii) shares of Common Stock

or non-debt Common Stock Equivalents issued and/or issuable to Cytovance Biologics, Inc. in connection with that certain Settlement and

Investment Agreement dated August 24, 2022 (as amended), between the Company and Cytovance Biologics, Inc., with the aggregate value

of such shares or non-debt Common Stock Equivalents not to exceed more than $1,000,000 in unregistered issuances in a single twelve-month

period, and (iii) shares of Common Stock or non-debt Common Stock Equivalents issued and/or issuable pursuant to the settlement and release

of claim agreements currently being negotiated by the Company with Cody Riddle Silberfein (“Silberfein”), Justin DiPietro

(“DiPietro”) and the Werthman Trust, and with respect to Silberfein and DiPietro, the related exchange agreement, with the

aggregate value of such shares or non-debt Common Stock Equivalents not to exceed more than $300,000, provided that the effective Common

Stock per share price is not less than the Nasdaq Official Closing Price on the date used to calculate the quantity of shares due under

the applicable Settlement Agreement, and provided further that no amendment or modification to either such agreement shall be made without

first obtaining the prior written consent of the two largest Purchasers hereunder (based on initial Subscription Amounts).

30

4.13

Subsequent Equity Sales.

(a)

From the date hereof until 30 days after the later of (i) the Effective Date and (ii) the date that Shareholder Approval is obtained

and deemed effective, neither the Company nor any Subsidiary shall issue, enter into any agreement to issue or announce the issuance

or proposed issuance of any shares of Common Stock or Common Stock Equivalents or (ii) file any registration statement or any amendment

or supplement thereto, in each case other than as contemplated pursuant to the Registration Rights Agreement.

(b)

From the date hereof until such time as no Purchaser holds any of the Preferred Stock or Warrants, the Company shall be prohibited from

effecting or entering into an agreement to effect any issuance by the Company or any of its Subsidiaries of Common Stock or Common Stock

Equivalents (or a combination of units thereof) involving a Variable Rate Transaction. “Variable Rate Transaction”

means a transaction in which the Company (i) issues or sells any debt or equity securities that are convertible into, exchangeable or

exercisable for, or include the right to receive, additional shares of Common Stock either (A) at a conversion price, exercise price

or exchange rate or other price that is based upon, and/or varies with, the trading prices of or quotations for the shares of Common

Stock at any time after the initial issuance of such debt or equity securities or (B) with a conversion, exercise or exchange price that

is subject to being reset at some future date after the initial issuance of such debt or equity security or upon the occurrence of specified

or contingent events directly or indirectly related to the business of the Company or the market for the Common Stock or (ii) enters

into, or effects a transaction under, any agreement, including, but not limited to, an equity line of credit or an “at-the-market

offering”, whereby the Company may issue securities at a future determined price regardless of whether shares pursuant to such

agreement have actually been issued and regardless of whether such agreement is subsequently canceled; provided, however,

that, from the date hereof and until the two-year anniversary of the Closing Date, the Company shall be permitted to undertake an equity

line of credit facility with Hailstone Peak Funding LLC without the consent of the other Purchasers in the amount not to exceed $20,000,000.

(c)

Notwithstanding the foregoing, this Section 4.13 shall not apply in respect of (i) an Exempt Issuance, except that no Variable Rate Transaction

shall be an Exempt Issuance and (ii) shares of Common Stock or non-debt Common Stock Equivalents issued and/or issuable to Cytovance

Biologics, Inc. in connection with that certain Settlement and Investment Agreement dated August 24, 2022 (as amended), between the Company

and Cytovance Biologics, Inc., with the aggregate value of such shares or non-debt Common Stock Equivalents not to exceed more than $1,000,000

in unregistered issuances in a single twelve-month period, and (iii) shares of Common Stock or non-debt Common Stock Equivalents issued

and/or issuable pursuant to the settlement and release of claim agreements currently being negotiated by the Company with Silberfein,

DiPietro and the Werthman Trust, and with respect to Silberfein and DiPietro, the related exchange agreement, with the aggregate value

of such shares or non-debt Common Stock Equivalents not to exceed more than $300,000, provided that the effective Common Stock per share

price is not less than the Nasdaq Official Closing Price on the date used to calculate the quantity of shares due under the applicable

Settlement Agreement, and provided further that no amendment or modification to either such agreement shall be made without first obtaining

the prior written consent of the two largest Purchasers hereunder (based on initial Subscription Amounts).

31

4.14

Equal Treatment of Purchasers. No consideration (including any modification of any Transaction Document) shall be offered or paid

to any Person to amend or consent to a waiver or modification of any provision of the Transaction Documents unless the same consideration

is also offered to all of the parties to the Transaction Documents. For clarification purposes, this provision constitutes a separate

right granted to each Purchaser by the Company and negotiated separately by each Purchaser, and is intended for the Company to treat

the Purchasers as a class and shall not in any way be construed as the Purchasers acting in concert or as a group with respect to the

purchase, disposition or voting of Securities or otherwise.

4.15

Certain Transactions and Confidentiality. Each Purchaser, severally and not jointly with the other Purchasers, covenants that

neither it, nor any Affiliate acting on its behalf or pursuant to any understanding with it will execute any purchases or sales, including

Short Sales, of any of the Company’s securities during the period commencing with the execution of this Agreement and ending at

such time that the transactions contemplated by this Agreement are first publicly announced pursuant to the initial press release as

described in Section 4.6. Each Purchaser, severally and not jointly with the other Purchasers, covenants that until such time as the

transactions contemplated by this Agreement are publicly disclosed by the Company pursuant to the initial press release as described

in Section 4.6, such Purchaser will maintain the confidentiality of the existence and terms of this transaction and the information included

in the Disclosure Schedules (other than as disclosed to its legal and other representatives). Notwithstanding the foregoing, and notwithstanding

anything contained in this Agreement to the contrary, the Company expressly acknowledges and agrees that (i) no Purchaser makes any representation,

warranty or covenant hereby that it will not engage in effecting transactions in any securities of the Company after the time that the

transactions contemplated by this Agreement are first publicly announced pursuant to the initial press release as described in Section

4.6, (ii) no Purchaser shall be restricted or prohibited from effecting any transactions in any securities of the Company in accordance

with applicable securities laws from and after the time that the transactions contemplated by this Agreement are first publicly announced

pursuant to the initial press release as described in Section 4.6 and (iii) no Purchaser shall have any duty of confidentiality or duty

not to trade in the securities of the Company to the Company, any of its Subsidiaries, or any of their respective officers, directors,

employees, Affiliates or agent, including, after the issuance of the initial press release as described in Section 4.6. Notwithstanding

the foregoing, in the case of a Purchaser that is a multi-managed investment vehicle whereby separate portfolio managers manage separate

portions of such Purchaser’s assets and the portfolio managers have no direct knowledge of the investment decisions made by the

portfolio managers managing other portions of such Purchaser’s assets, the covenant set forth above shall only apply with respect

to the portion of assets managed by the portfolio manager that made the investment decision to purchase the Securities covered by this

Agreement.

4.16

Form D; Blue Sky Filings. The Company agrees to timely file a Form D with respect to the Securities as required under Regulation

D and to provide a copy thereof, promptly upon request of any Purchaser. The Company shall take such action as the Company shall reasonably

determine is necessary in order to obtain an exemption for, or to qualify the Securities for, sale to the Purchasers at the Closing under

applicable securities or “Blue Sky” laws of the states of the United States, and shall provide evidence of such actions promptly

upon request of any Purchaser.

4.17

Capital Changes. Until the one year anniversary of the later of (a) the Effective Date and (b) the date that Shareholder Approval

is obtained and deemed effective, the Company shall not undertake a reverse or forward stock split or reclassification of the Common

Stock without the prior written consent of the Purchasers holding a majority in interest of the shares of Preferred Stock.

4.18

Lock-Up Agreements. The Company shall not amend, modify, waive or terminate any provision of any of the Lock-Up Agreements except

to extend the term of the lock-up period and shall enforce the provisions of each Lock-Up Agreement in accordance with its terms. If

any party to a Lock-Up Agreement breaches any provision of a Lock-Up Agreement, the Company shall promptly use commercially reasonable

efforts to seek specific performance of the terms of such Lock-Up Agreement.

4.19

No Broker-Dealer. The Company acknowledges and agrees that the Purchasers are not acting as a broker, dealer, underwriter or agent

of the Company or any of its Subsidiaries. The Company and its Subsidiaries shall not, and the Company shall direct its agents, affiliates

and representatives not to, take the position that the Purchasers are acting in any manner as a broker, dealer or agent of the Company

or any of its Subsidiaries in any respect (whether pursuant to the transactions contemplated hereby or otherwise).

32

ARTICLE

V.

MISCELLANEOUS

5.1

Termination. This Agreement may be terminated by any Purchaser, as to such Purchaser’s obligations hereunder only and without

any effect whatsoever on the obligations between the Company and the other Purchasers, by written notice to the other parties, if the

Closing has not been consummated on or before the fifth (5th) Trading Day following the date hereof; provided, however,

that no such termination will affect the right of any party to sue for any breach by any other party (or parties).

5.2

Fees and Expenses. At the Closing, the Company has agreed to reimburse the two largest Purchasers hereunder (based on Subscription

Amounts) for their reasonable legal fees and expenses. Except as expressly set forth in the Transaction Documents to the contrary, each

party shall pay the fees and expenses of its advisers, counsel, accountants and other experts, if any, and all other expenses incurred

by such party incident to the negotiation, preparation, execution, delivery and performance of this Agreement. The Company shall pay

all Transfer Agent fees (including, without limitation, any fees required for same-day processing of any instruction letter delivered

by the Company and any conversion or exercise notice delivered by a Purchaser), stamp taxes and other taxes and duties levied in connection

with the delivery of any Securities to the Purchasers.

5.3

Entire Agreement. The Transaction Documents, together with the exhibits and schedules thereto, contain the entire understanding

of the parties with respect to the subject matter hereof and thereof and supersede all prior agreements and understandings, oral or written,

with respect to such matters, which the parties acknowledge have been merged into such documents, exhibits and schedules.

5.4

Notices. Any and all notices or other communications or deliveries required or permitted to be provided hereunder shall be in

writing and shall be deemed given and effective on the earliest of: (a) the time of transmission, if such notice or communication is

delivered via email attachment at the e-mail address as set forth on the signature pages attached hereto at or prior to 5:30 p.m. (New

York City time) on a Trading Day, (b) the next Trading Day after the time of transmission, if such notice or communication is delivered

via email attachment at the e-mail address as set forth on the signature pages attached hereto on a day that is not a Trading Day or

later than 5:30 p.m. (New York City time) on any Trading Day, (c) the second (2nd) Trading Day following the date of mailing,

if sent by U.S. nationally recognized overnight courier service or (d) upon actual receipt by the party to whom such notice is required

to be given. The address for such notices and communications shall be as set forth on the signature pages attached hereto.

5.5

Amendments; Waivers. No provision of this Agreement may be waived, modified, supplemented or amended except in a written instrument

signed, in the case of an amendment, by the Company and Purchasers which purchased at least 50.1% in interest of the Preferred Stock

based on the initial Subscription Amounts hereunder (or, prior to the Closing, the Company and each Purchaser) or, in the case of a waiver,

by the party against whom enforcement of any such waived provision is sought, provided that if any amendment, modification or waiver

disproportionately and adversely impacts a Purchaser (or group of Purchasers), the consent of such disproportionately impacted Purchaser

(or group of Purchasers) shall also be required. No waiver of any default with respect to any provision, condition or requirement of

this Agreement shall be deemed to be a continuing waiver in the future or a waiver of any subsequent default or a waiver of any other

provision, condition or requirement hereof, nor shall any delay or omission of any party to exercise any right hereunder in any manner

impair the exercise of any such right. Any proposed amendment or waiver that disproportionately, materially and adversely affects the

rights and obligations of any Purchaser relative to the comparable rights and obligations of the other Purchasers shall require the prior

written consent of such adversely affected Purchaser. Any amendment effected in accordance with this Section 5.5 shall be binding upon

each Purchaser and holder of Securities and the Company.

5.6

Headings. The headings herein are for convenience only, do not constitute a part of this Agreement and shall not be deemed to

limit or affect any of the provisions hereof.

33

5.7

Successors and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their successors and

permitted assigns. The Company may not assign this Agreement or any rights or obligations hereunder without the prior written consent

of each Purchaser (other than by merger). Any Purchaser may assign any or all of its rights under this Agreement to any Person to whom

such Purchaser assigns or transfers any Securities, provided that such transferee agrees in writing to be bound, with respect to the

transferred Securities, by the provisions of the Transaction Documents that apply to the “Purchasers.”

5.8

No Third-Party Beneficiaries. This Agreement is intended for the benefit of the parties hereto and their respective successors

and permitted assigns and is not for the benefit of, nor may any provision hereof be enforced by, any other Person, except as otherwise

set forth in Section 4.10 and this Section 5.8.

5.9

Governing Law. All questions concerning the construction, validity, enforcement and interpretation of the Transaction Documents

shall be governed by and construed and enforced in accordance with the internal laws of the State of New York, without regard to the

principles of conflicts of law thereof. Each party agrees that all legal Proceedings concerning the interpretations, enforcement and

defense of the transactions contemplated by this Agreement and any other Transaction Documents (whether brought against a party hereto

or its respective affiliates, directors, officers, shareholders, partners, members, employees or agents) shall be commenced exclusively

in the state and federal courts sitting in the City of New York. Each party hereby irrevocably submits to the exclusive jurisdiction

of the state and federal courts sitting in the City of New York, Borough of Manhattan for the adjudication of any dispute hereunder or

in connection herewith or with any transaction contemplated hereby or discussed herein (including with respect to the enforcement of

any of the Transaction Documents), and hereby irrevocably waives, and agrees not to assert in any Action or Proceeding, any claim that

it is not personally subject to the jurisdiction of any such court, that such Action or Proceeding is improper or is an inconvenient

venue for such Proceeding. Each party hereby irrevocably waives personal service of process and consents to process being served in any

such Action or Proceeding by mailing a copy thereof via registered or certified mail or overnight delivery (with evidence of delivery)

to such party at the address in effect for notices to it under this Agreement and agrees that such service shall constitute good and

sufficient service of process and notice thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process

in any other manner permitted by law. If any party shall commence an Action or Proceeding to enforce any provisions of the Transaction

Documents, then, in addition to the obligations of the Company under Section 4.10, the prevailing party in such Action or Proceeding

shall be reimbursed by the non-prevailing party for its reasonable attorneys’ fees and other costs and expenses incurred with the

investigation, preparation and prosecution of such Action or Proceeding.

5.10

Survival. The representations and warranties contained herein shall survive the Closing and the delivery of the Securities.

5.11

Execution. This Agreement may be executed in two or more counterparts, all of which when taken together shall be considered one

and the same agreement and shall become effective when counterparts have been signed by each party and delivered to each other party,

it being understood that the parties need not sign the same counterpart. In the event that any signature is delivered by e-mail delivery

of a “.pdf” format data file, such signature shall create a valid and binding obligation of the party executing (or on whose

behalf such signature is executed) with the same force and effect as if such “.pdf” signature page were an original thereof.

5.12

Severability. If any term, provision, covenant or restriction of this Agreement is held by a court of competent jurisdiction to

be invalid, illegal, void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein shall

remain in full force and effect and shall in no way be affected, impaired or invalidated, and the parties hereto shall use their commercially

reasonable efforts to find and employ an alternative means to achieve the same or substantially the same result as that contemplated

by such term, provision, covenant or restriction. It is hereby stipulated and declared to be the intention of the parties that they would

have executed the remaining terms, provisions, covenants and restrictions without including any of such that may be hereafter declared

invalid, illegal, void or unenforceable.

34

5.13

Rescission and Withdrawal Right. Notwithstanding anything to the contrary contained in (and without limiting any similar provisions

of) any of the other Transaction Documents, whenever any Purchaser exercises a right, election, demand or option under a Transaction

Document and the Company does not timely perform its related obligations within the periods therein provided, then such Purchaser may

rescind or withdraw, in its sole discretion from time to time upon written notice to the Company, any relevant notice, demand or election

in whole or in part without prejudice to its future actions and rights; provided, however, that, in the case of a rescission

of a conversion of the Preferred Stock or exercise of a Warrant, the applicable Purchaser shall be required to return any shares of Common

Stock subject to any such rescinded conversion or exercise notice concurrently with the return to such Purchaser of the aggregate exercise

price paid to the Company for such shares and the restoration of such Purchaser’s right to acquire such shares pursuant to such

Purchaser’s Warrant (including, issuance of a replacement warrant certificate evidencing such restored right).

5.14

Replacement of Securities. If any certificate or instrument evidencing any Securities is mutilated, lost, stolen or destroyed,

the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation thereof (in the case of mutilation),

or in lieu of and substitution therefor, a new certificate or instrument, but only upon receipt of evidence reasonably satisfactory to

the Company of such loss, theft or destruction. The applicant for a new certificate or instrument under such circumstances shall also

pay any reasonable third-party costs (including customary indemnity) associated with the issuance of such replacement Securities.

5.15

Remedies. In addition to being entitled to exercise all rights provided herein or granted by law, including recovery of damages,

each of the Purchasers and the Company will be entitled to specific performance under the Transaction Documents. The parties agree that

monetary damages may not be adequate compensation for any loss incurred by reason of any breach of obligations contained in the Transaction

Documents and hereby agree to waive and not to assert in any Action for specific performance of any such obligation the defense that

a remedy at law would be adequate.

5.16

Payment Set Aside. To the extent that the Company makes a payment or payments to any Purchaser pursuant to any Transaction Document

or a Purchaser enforces or exercises its rights thereunder, and such payment or payments or the proceeds of such enforcement or exercise

or any part thereof are subsequently invalidated, declared to be fraudulent or preferential, set aside, recovered from, disgorged by

or are required to be refunded, repaid or otherwise restored to the Company, a trustee, receiver or any other Person under any law (including,

without limitation, any bankruptcy law, state or federal law, common law or equitable cause of action), then to the extent of any such

restoration the obligation or part thereof originally intended to be satisfied shall be revived and continued in full force and effect

as if such payment had not been made or such enforcement or setoff had not occurred.

5.17

Usury. To the extent it may lawfully do so, the Company hereby agrees not to insist upon or plead or in any manner whatsoever

claim, and will resist any and all efforts to be compelled to take the benefit or advantage of, usury laws wherever enacted, now or at

any time hereafter in force, in connection with any Action or Proceeding that may be brought by any Purchaser in order to enforce any

right or remedy under any Transaction Document. Notwithstanding any provision to the contrary contained in any Transaction Document,

it is expressly agreed and provided that the total liability of the Company under the Transaction Documents for payments in the nature

of interest shall not exceed the maximum lawful rate authorized under applicable law (the “Maximum Rate”), and, without

limiting the foregoing, in no event shall any rate of interest or default interest, or both of them, when aggregated with any other sums

in the nature of interest that the Company may be obligated to pay under the Transaction Documents exceed such Maximum Rate. It is agreed

that if the maximum contract rate of interest allowed by law and applicable to the Transaction Documents is increased or decreased by

statute or any official governmental action subsequent to the date hereof, the new maximum contract rate of interest allowed by law will

be the Maximum Rate applicable to the Transaction Documents from the effective date thereof forward, unless such application is precluded

by applicable law. If under any circumstances whatsoever, interest in excess of the Maximum Rate is paid by the Company to any Purchaser

with respect to indebtedness evidenced by the Transaction Documents, such excess shall be applied by such Purchaser to the unpaid principal

balance of any such indebtedness or be refunded to the Company, the manner of handling such excess to be at such Purchaser’s election.

35

5.18

Independent Nature of Purchasers’ Obligations and Rights. The obligations of each Purchaser under any Transaction Document

are several and not joint with the obligations of any other Purchaser, and no Purchaser shall be responsible in any way for the performance

or non-performance of the obligations of any other Purchaser under any Transaction Document. Nothing contained herein or in any other

Transaction Document, and no action taken by any Purchaser pursuant hereto or thereto, shall be deemed to constitute the Purchasers as

a partnership, an association, a joint venture or any other kind of entity, or create a presumption that the Purchasers are in any way

acting in concert or as a group with respect to such obligations or the transactions contemplated by the Transaction Documents. Each

Purchaser shall be entitled to independently protect and enforce its rights, including, without limitation, the rights arising out of

this Agreement or out of the other Transaction Documents, and it shall not be necessary for any other Purchaser to be joined as an additional

party in any Proceeding for such purpose. Each Purchaser has been represented by its own separate legal counsel in its review and negotiation

of the Transaction Documents. Five Narrow Lane Counsel does not represent any of the Purchasers and only represents Five Narrow Lane,

L.P. The Company has elected to provide all Purchasers with the same terms and Transaction Documents for the convenience of the Company

and not because it was required or requested to do so by any of the Purchasers. It is expressly understood and agreed that each provision

contained in this Agreement and in each other Transaction Document is between the Company and a Purchaser, solely, and not between the

Company and the Purchasers collectively and not between and among the Purchasers.

5.19

Liquidated Damages. The Company’s obligations to pay any partial liquidated damages or other amounts owing under the Transaction

Documents is a continuing obligation of the Company and shall not terminate until all unpaid partial liquidated damages and other amounts

have been paid notwithstanding the fact that the instrument or security pursuant to which such partial liquidated damages or other amounts

are due and payable shall have been canceled.

5.20

Saturdays, Sundays, Holidays, etc. If the last or appointed day for the taking of any action or the expiration of any right required

or granted herein shall not be a Business Day, then such action may be taken or such right may be exercised on the next succeeding Business

Day.

5.21

Construction. The parties agree that each of them and/or their respective counsel have reviewed and had an opportunity to revise

the Transaction Documents and, therefore, the normal rule of construction to the effect that any ambiguities are to be resolved against

the drafting party shall not be employed in the interpretation of the Transaction Documents or any amendments thereto. In addition, each

and every reference to share prices and shares of Common Stock in any Transaction Document shall be subject to adjustment for reverse

and forward stock splits, stock dividends, stock combinations and other similar transactions of the Common Stock that occur after the

date of this Agreement.

5.22

WAIVER OF JURY TRIAL. IN ANY ACTION, SUIT, OR PROCEEDING IN ANY JURISDICTION BROUGHT BY ANY PARTY AGAINST ANY OTHER PARTY,

THE PARTIES EACH KNOWINGLY AND INTENTIONALLY, TO THE GREATEST EXTENT PERMITTED BY APPLICABLE LAW, HEREBY ABSOLUTELY, UNCONDITIONALLY,

IRREVOCABLY AND EXPRESSLY WAIVES FOREVER TRIAL BY JURY.

(Signature

Pages Follow)

36

IN

WITNESS WHEREOF, the parties hereto have caused this Securities Purchase Agreement to be duly executed by their respective authorized

signatories as of the date first indicated above.

gt biophARMA, INC.

Address

for Notice:

505

Montgomery Street, 10th Floor

San

Francisco, CA 94111

E-Mail:

mb@gtbiopharma.com

By:

Michael Breen

Title:

Executive Chairman &

Chief Executive Officer

With

a copy to (which shall not constitute notice):

Baker

& Hostetler, LLP

1900 Avenue of the Stars, Suite 2700   Los Angeles, CA 90067

Attention: JR Lanis

Email: jrlanis@bakerlaw.com

[REMAINDER

OF PAGE INTENTIONALLY LEFT BLANK

SIGNATURE

PAGE FOR PURCHASER FOLLOWS]

37

[PURCHASER

SIGNATURE PAGES TO GTBP SECURITIES PURCHASE AGREEMENT]

IN

WITNESS WHEREOF, the undersigned have caused this Securities Purchase Agreement to be duly executed by their respective authorized signatories

as of the date first indicated above.

Name

of Purchaser: ____________________________________________________

Signature

of Authorized Signatory of Purchaser: __________________________

Name

of Authorized Signatory: ____________________________________

Title

of Authorized Signatory: _____________________________________

Email

Address of Authorized Signatory: ___________________________________________

Address

for Notice to Purchaser:

Address

for Delivery of Securities to Purchaser (if not same as address for notice):

Subscription

Amount (amount of investment): $____________

Preferred

Stock Stated Value (Subscription Amount divided by 90%): ____________

Shares

of Preferred Stock (Preferred Stock Stated Value divided by 1,000): ____________

Warrant

Shares: ________________ Beneficial Ownership Blocker ☐4.99%/☐ 9.99%

EIN

Number: _______________________

[SIGNATURE

PAGES CONTINUE]

38

EXHIBIT

A

CERTIFICATE

OF DESIGNATION

EXHIBIT

B

REGISTRATION

RIGHTS AGREEMENT

EXHIBIT

C

COMMON

STOCK WARRANTS

EXHIBIT

D

VESTING

WARRANTS

EXHIBIT

E

LOCK-UP

AGREEMENT

EXHIBIT

F

VOTING

AGREEMENT

EX-10.2

EX-10.2

Filename: ex10-2.htm · Sequence: 6

Exhibit 10.2

REGISTRATION

RIGHTS AGREEMENT

This

Registration Rights Agreement (this “Agreement”) is made and entered into as of September 14, 2026, between GT Biopharma,

Inc., a Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser,

a “Purchaser” and, collectively, the “Purchasers”).

This

Agreement is made pursuant to the Securities Purchase Agreement, dated as of the date hereof, between the Company and each Purchaser

(the “Purchase Agreement”).

NOW

THEREFORE, in consideration of the mutual covenants contained in this Agreement, and for other good and valuable consideration, the receipt

and adequacy of which are hereby acknowledged, the Company and each Purchaser hereby agrees as follows:

1.

Definitions.

Capitalized

terms used and not otherwise defined herein that are defined in the Purchase Agreement shall have the meanings given such terms in the

Purchase Agreement. As used in this Agreement, the following terms shall have the following meanings:

“Advice”

shall have the meaning set forth in Section 6(c).

“Effectiveness

Date” means the 60th calendar day following the Closing Date and each Trigger Date, as applicable (or, in the event

of a “full review” by the Commission, the 90th calendar day following the Closing Date and each Trigger Date,

as applicable) and with respect to any additional Registration Statements which may be required pursuant to Section 2(c) or Section 3(c),

the 60th calendar day following the date on which an additional Registration Statement is required to be filed hereunder (or,

in the event of a “full review” by the Commission, the 90th calendar day following the date such additional Registration

Statement is required to be filed hereunder); provided, however, that in the event the Company is notified by the Commission

that one or more of the above Registration Statements will not be reviewed or is no longer subject to further review and comments, the

Effectiveness Date as to such Registration Statement shall be the fifth Trading Day following the date on which the Company is so notified

if such date precedes the dates otherwise required above, provided, further, if such Effectiveness Date falls on a day that is not a

Trading Day, then the Effectiveness Date shall be the next succeeding Trading Day.

“Effectiveness

Period” shall have the meaning set forth in Section 2(a).

“Event”

shall have the meaning set forth in Section 2(d).

“Event

Date” shall have the meaning set forth in Section 2(d).

“Filing

Date” means the 30th calendar day following the Closing Date and each Trigger Date, as applicable, and, with respect

to any additional Registration Statements which may be required pursuant to Section 2(c) or Section 3(c), the earliest practical date

on which the Company is permitted by SEC Guidance to file such additional Registration Statement related to the Registrable Securities,

provided, further, if such Filing Date falls on a day that is not a Trading Day, then the Filing Date shall be the next succeeding Trading

Day.

“Holder”

or “Holders” means the holder or holders, as the case may be, from time to time of Registrable Securities.

“Indemnified

Party” shall have the meaning set forth in Section 5(c).

“Indemnifying

Party” shall have the meaning set forth in Section 5(c).

“Losses”

shall have the meaning set forth in Section 5(a).

“Plan

of Distribution” shall have the meaning set forth in Section 2(a).

“Prime

Rate” means the rate last quoted by The Wall Street Journal as the “Prime Rate” in the United States or, if The

Wall Street Journal ceases to quote such rate, the highest per annum interest rate published by the Federal Reserve Board in Federal

Reserve Statistical Release H.15 (519) (Selected Interest Rates) as the “bank prime loan” rate or, if such rate is no longer

quoted therein, any similar rate quoted therein or any similar release by the Federal Reserve Board.

“Prospectus”

means the prospectus included in a Registration Statement (including, without limitation, a prospectus that includes any information

previously omitted from a prospectus filed as part of an effective registration statement in reliance upon Rule 430A promulgated by the

Commission pursuant to the Securities Act), as amended or supplemented by any prospectus supplement, with respect to the terms of the

offering of any portion of the Registrable Securities covered by a Registration Statement, and all other amendments and supplements to

the Prospectus, including post-effective amendments, and all material incorporated by reference or deemed to be incorporated by reference

in such Prospectus.

2

“Registrable

Securities” means, as of any date of determination and provided that the Holder has completed and delivered to the Company

a Selling Stockholder Questionnaire, (a) all Conversion Shares issued and issuable pursuant to then outstanding Preferred Stock (assuming

on such date the Preferred Stock is converted in full without regard to any conversion limitations therein and the Conversion Price equals

the Floor Price), (b) all Warrant Shares issued and issuable upon exercise of the Warrants (assuming on such date the Warrants are exercised

in full without regard to any exercise limitations therein and assuming the Exercise Price equals the Floor Price) and (c) any securities

issued or then issuable upon any stock split, dividend or other distribution, recapitalization or similar event with respect to the foregoing;

provided, however, that until Shareholder Approval (as defined in the Purchase Agreement) is obtained, the Registrable

Securities shall not include the Greenshoe Conversion Shares (as defined in the Purchase Agreement) or the Vesting Warrant Shares (as

defined in the Purchase Agreement); provided, further however, that any such Registrable Securities shall cease to be Registrable

Securities (and the Company shall not be required to maintain the effectiveness of any, or file another, Registration Statement hereunder

with respect thereto) for so long as (a) a Registration Statement with respect to the sale of such Registrable Securities is declared

effective by the Commission under the Securities Act and such Registrable Securities have been disposed of by the Holder in accordance

with such effective Registration Statement, (b) such Registrable Securities have been previously sold in accordance with Rule 144, or

(c) such securities become eligible for resale without volume or manner-of-sale restrictions and without current public information pursuant

to Rule 144 as set forth in a written opinion letter to such effect, addressed, delivered and acceptable to the Transfer Agent and the

affected Holders (assuming that such securities and any securities issuable upon exercise, conversion or exchange of which, or as a dividend

upon which, such securities were issued or are issuable, were at no time held by any Affiliate of the Company, as reasonably determined

by the Company, upon the advice of counsel to the Company).

“Registration

Statement” means any registration statement required to be filed hereunder pursuant to Section 2(a) and any additional registration

statements contemplated by Section 2(c) or Section 3(c), including (in each case) the Prospectus, amendments and supplements to any such

registration statement or Prospectus, including pre- and post-effective amendments, all exhibits thereto, and all material incorporated

by reference or deemed to be incorporated by reference in any such registration statement.

“Rule

415” means Rule 415 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted

from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose and effect

as such Rule.

“Rule

424” means Rule 424 promulgated by the Commission pursuant to the Securities Act, as such Rule may be amended or interpreted

from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same purpose and effect

as such Rule.

“SEC

Guidance” means (i) any publicly-available written or oral guidance of the Commission staff, or any comments, requirements

or requests of the Commission staff and (ii) the Securities Act.

3

“Selling

Stockholder Questionnaire” shall have the meaning set forth in Section 3(a).

“Trigger

Date” means the 45th calendar day following each Greenshoe Closing prior to the Shareholder Approval and the 30th

calendar day following each Greenshoe Closing after the Shareholder Approval.

2.

Shelf Registration.

(a)

On or prior to each Filing Date, the Company shall prepare and file with the Commission a Registration Statement covering the resale

of all of the Registrable Securities that are not then registered on an effective Registration Statement for an offering to be made on

a continuous basis pursuant to Rule 415. Each Registration Statement filed hereunder shall be on Form S-3 (except if the Company is not

then eligible to register for resale the Registrable Securities on Form S-3, in which case such registration shall be on another appropriate

form in accordance herewith, subject to the provisions of Section 2(e)) and shall contain (unless otherwise directed by at least 85%

in interest of the Holders) substantially the “Plan of Distribution” attached hereto as Annex A and substantially

the “Selling Stockholder” section attached hereto as Annex B; provided, however, that no Holder

or affiliate of a Holder shall be required to be named as, and in no event shall the Company be permitted to name any Holder or affiliate

of a Holder as, an “underwriter” without such Holder’s express prior written consent. Subject to the terms of this

Agreement, the Company shall use commercially reasonable efforts to cause a Registration Statement filed under this Agreement (including,

without limitation, under Section 3(c)) to be declared effective under the Securities Act as promptly as possible after the filing thereof,

but in any event no later than the applicable Effectiveness Date, and shall use commercially reasonable efforts to keep such Registration

Statement continuously effective under the Securities Act until the date that all Registrable Securities covered by such Registration

Statement (i) have been sold, thereunder or pursuant to Rule 144, or (ii) may be sold without volume or manner-of-sale restrictions pursuant

to Rule 144 and without the requirement for the Company to be in compliance with the current public information requirement under Rule

144, as determined by counsel to the Company pursuant to a written opinion letter to such effect, addressed and acceptable to the Transfer

Agent and the affected Holders (the “Effectiveness Period”). The Company shall telephonically request effectiveness

of a Registration Statement as of 5:00 p.m. (New York City time) on a Trading Day. Notwithstanding anything herein to the contrary, as

to the initial Registration Statement, the Company shall submit a Registration Statement including all of the Registrable Securities

represented by Underlying Shares issuable pursuant to the Securities issued at the Closing. The Company shall immediately notify the

Holders via e-mail of the effectiveness of a Registration Statement on the same Trading Day that the Company telephonically confirms

effectiveness with the Commission, which shall be the date requested for effectiveness of such Registration Statement. The Company shall,

by 9:30 a.m. (New York City time) on the Trading Day after the effective date of such Registration Statement, file a final Prospectus

with the Commission as required by Rule 424. Failure to so notify the Holder within one (1) Trading Day of such notification of effectiveness

or failure to file a final Prospectus as foresaid shall be deemed an Event under Section 2(d).

4

(b)

Notwithstanding the registration obligations set forth in Section 2(a), if the Commission informs the Company that all of the Registrable

Securities cannot, as a result of the application of Rule 415, be registered for resale as a secondary offering on a single registration

statement, the Company agrees to promptly inform each of the Holders thereof and use its commercially reasonable efforts to file amendments

to each Registration Statement as required by the Commission, covering the maximum number of Registrable Securities permitted to be registered

by the Commission, on Form S-3 or such other form available to register for resale the Registrable Securities as a secondary offering,

subject to the provisions of Section 2(e) with respect to filing on Form S-3 or other appropriate form, and subject to the provisions

of Section 2(d) with respect to the payment of liquidated damages; provided, however, that prior to filing such amendment,

the Company shall be obligated to use commercially reasonable efforts to advocate with the Commission for the registration of all of

the Registrable Securities in accordance with the SEC Guidance, including without limitation, Corporation Finance Interpretation 612.09.

(c)

Notwithstanding any other provision of this Agreement and subject to the payment of liquidated damages pursuant to Section 2(d), if the

Commission or any SEC Guidance sets forth a limitation on the number of Registrable Securities permitted to be registered on a particular

Registration Statement as a secondary offering (and notwithstanding that the Company used commercially reasonable efforts to advocate

with the Commission for the registration of all or a greater portion of Registrable Securities), unless otherwise directed in writing

by a Holder as to its Registrable Securities, the number of Registrable Securities to be registered on such Registration Statement will

be reduced as follows:

a.

First, the Company shall reduce or eliminate any securities

to be included other than the Registrable Securities;

b.

Second, the Company shall reduce the Registrable Securities

represented by the Conversion Shares underlying the Preferred Stock issuable pursuant to the Greenshoe Rights and Vesting Warrant Shares

(applied, in the case that some of such Registrable Securities may be registered but not all, to the Holders on a pro rata basis based

on each Holder’s Subscription Amount at the Closing, and within such pro rata amounts one (1) Conversion Share to one (1) Vesting

Warrant Share);

c.

Third, the Company shall reduce Registrable Securities represented

by Common Stock Warrant Shares (applied, in the case that some of such Common Stock Warrant Shares may be registered but not all, to

the Holders on a pro rata basis based on each Holder’s Subscription Amount at the Closing); and

d.

Fourth, the Company shall reduce Registrable Securities represented

by the Conversion Shares underlying the Preferred Stock issued at the Closing (applied, in the case that some of such Conversions Shares

may be registered but not all, to the Holders on a pro rata basis based on each Holder’s Subscription Amount at the Closing).

In

the event of a cutback hereunder, the Company shall give the Holder at least three (3) Trading Days prior written notice along with the

calculations as to such Holder’s allotment. In the event the Company amends a Registration Statement in accordance with the foregoing,

the Company will use commercially reasonable efforts to file with the Commission, as promptly as allowed by Commission or SEC Guidance

provided to the Company or to registrants of securities in general, one or more registration statements on Form S-3 or such other form

available to register for resale those Registrable Securities that were not registered for resale on each Registration Statement, as

amended.

5

(d)

If: (i) a Registration Statement is not filed on or prior to its respective Filing Date (if the Company files a Registration Statement

without affording the Holders the opportunity to review and comment on the same as required by Section 3(a) herein or the Company subsequently

withdraws the filing of a Registration Statement, the Company shall be deemed to have not satisfied this clause (i) as of the respective

Filing Date), or (ii) the Company fails to file with the Commission a request for acceleration of effectiveness of a Registration Statement

in accordance with Rule 461 promulgated by the Commission pursuant to the Securities Act, within five Trading Days of the date that the

Company is notified (orally or in writing, whichever is earlier) by the Commission that such Registration Statement will not be “reviewed”

or will not be subject to further review, or (iii) prior to the effective date of a Registration Statement, the Company fails to file

a pre-effective amendment and otherwise respond in writing to comments made by the Commission in respect of such Registration Statement

within ten (10) calendar days after the receipt of comments by or notice from the Commission that such amendment is required in order

for such Registration Statement to be declared effective, or (iv) a Registration Statement registering for resale all of the Registrable

Securities required by the terms of this Agreement to be registered for resale is not declared effective by the Commission by the respective

Effectiveness Date of each Registration Statement (provided that, if a Registration Statement does not allow for the resale of Registrable

Securities at prevailing market prices (i.e., only allows for fixed price sales), the Company shall have been deemed to have not satisfied

this clause) or (v) after the effective date of a Registration Statement, such Registration Statement ceases for any reason to remain

continuously effective as to all Registrable Securities included in such Registration Statement, or the Holders are otherwise not permitted

to utilize the Prospectus therein to resell such Registrable Securities, for more than ten (10) consecutive calendar days or more than

an aggregate of fifteen (15) calendar days (which need not be consecutive calendar days) during any 12-month period (any such failure

or breach being referred to as an “Event”, and for purposes of clauses (i) and (iv), the date on which such Event

occurs, and for purpose of clause (ii) the date on which such five (5) Trading Day period is exceeded, and for purpose of clause (iii)

the date which such ten (10) calendar day period is exceeded, and for purpose of clause (v) the date on which such ten (10) or fifteen

(15) calendar day period, as applicable, is exceeded being referred to as “Event Date”), then, in addition to any

other rights the Holders may have hereunder or under applicable law, on each such Event Date and on each monthly anniversary of each

such Event Date (if the applicable Event shall not have been cured by such date) until the applicable Event is cured, the Company shall

pay to each Holder an amount in cash, as partial liquidated damages and not as a penalty, equal to the product of 1.5% multiplied by

the aggregate Subscription Amount paid by such Holder pursuant to the Purchase Agreement (provided, as to the Subscription Amount payable

pursuant to the Greenshoe Rights, liquidated damages payable hereunder shall only accrue after the exercise thereof and after the applicable

Event Date with respect to such Greenshoe Rights has elapsed). If the Company fails to pay any partial liquidated damages pursuant to

this Section in full within seven days after the date payable, the Company will pay interest thereon at the Prime Rate plus 12% (or such

lesser maximum amount that is permitted to be paid by applicable law) to the Holder, accruing daily from the date such partial liquidated

damages are due until such amounts, plus all such interest thereon, are paid in full. The partial liquidated damages pursuant to the

terms hereof shall apply on a daily pro rata basis for any portion of a month prior to the cure of an Event.

(e)

If Form S-3 is not available for the registration of the resale of Registrable Securities hereunder, the Company shall (i) register the

resale of the Registrable Securities on another appropriate form and (ii) undertake to register the Registrable Securities on Form S-3

as soon as such form is available, provided that the Company shall maintain the effectiveness of a Registration Statement then in effect

until such time as a Registration Statement on Form S-3 covering the Registrable Securities has been declared effective by the Commission.

(f)

Notwithstanding anything to the contrary contained herein, in no event shall the Company be permitted to name any Holder or affiliate

of a Holder as any “underwriter” without the prior written consent of such Holder.

6

3.

Registration Procedures.

In

connection with the Company’s registration obligations hereunder, the Company shall:

(a)

Not less than five (5) Trading Days prior to the filing of each Registration Statement and not less than one (1) Trading Day prior to

the filing of any related Prospectus or any amendment or supplement thereto (including any document that would be incorporated or deemed

to be incorporated therein by reference other than Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q, Current Reports on Form

8-K and any similar or successor reports), the Company shall (i) furnish to each Holder copies of all such documents proposed to be filed,

which documents (other than those incorporated or deemed to be incorporated by reference) will be subject to the review of such Holders,

and (ii) cause its officers and directors, counsel and independent registered public accountants to respond to such inquiries as shall

be necessary, in the reasonable opinion of respective counsel to each Holder, to conduct a reasonable investigation within the meaning

of the Securities Act. The Company shall not file a Registration Statement or any such Prospectus or any amendments or supplements thereto

to which the Holders of a majority of the Registrable Securities shall reasonably object in good faith, provided that, the Company is

notified of such objection in writing no later than five (5) Trading Days after the Holders have been so furnished copies of a Registration

Statement or one (1) Trading Day after the Holders have been so furnished copies of any related Prospectus or amendments or supplements

thereto. Each Holder agrees to furnish to the Company a completed questionnaire in the form attached to this Agreement as Annex C

(a “Selling Stockholder Questionnaire”) on a date that is not less than two (2) Trading Days prior to the Filing Date

or by the end of the fourth (4th) Trading Day following the date on which such Holder receives draft materials in accordance

with this Section 3(a). Each Holder further agrees that it shall not be entitled to be named as a selling securityholder in any Registration

Statement or use the Prospectus for offers and resales of Registrable Securities at any time, unless such Holder has timely furnished

to the Company a completed and signed Selling Stockholder Questionnaire as described in the previous sentence.

(b)

(i) Prepare and file with the Commission such amendments, including post-effective amendments, to a Registration Statement and the Prospectus

used in connection therewith as may be necessary to keep a Registration Statement continuously effective as to the applicable Registrable

Securities for the Effectiveness Period and prepare and file with the Commission such additional Registration Statements in order to

register for resale under the Securities Act all of the Registrable Securities, (ii) cause the related Prospectus to be amended or supplemented

by any required Prospectus supplement (subject to the terms of this Agreement), and, as so supplemented or amended, to be filed pursuant

to Rule 424, (iii) respond as promptly as reasonably possible to any comments received from the Commission with respect to a Registration

Statement or any amendment thereto and provide as promptly as reasonably possible to the Holders true and complete copies of all correspondence

from and to the Commission relating to a Registration Statement (provided that, the Company shall excise any information contained therein

which would constitute material non-public information regarding the Company or any of its Subsidiaries), and (iv) comply in all material

respects with the applicable provisions of the Securities Act and the Exchange Act with respect to the disposition of all Registrable

Securities covered by a Registration Statement during the applicable period (subject to the terms of this Agreement) in accordance with

the intended methods of disposition by the Holders thereof set forth in such Registration Statement as so amended or in such Prospectus

as so supplemented; provided, however, that each Purchaser shall be responsible for the delivery of the Prospectus to the

Persons to whom such Purchaser sells any of the Shares or the Warrant Shares (including in accordance with Rule 172 under the Securities

Act), and each Purchaser agrees to dispose of Registrable Securities in compliance with the plan of distribution described in each Registration

Statement and otherwise in compliance with applicable federal and state securities laws.

7

(c)

If during the Effectiveness Period, the number of Registrable Securities at any time exceeds 100% of the number of shares of Common Stock

then registered in a Registration Statement, then the Company shall file as soon as reasonably practicable, but in any case prior to

the applicable Filing Date, an additional Registration Statement covering the resale by the Holders of not less than the number of such

Registrable Securities.

(d)

Notify the Holders of Registrable Securities to be sold (which notice shall, pursuant to clauses (iii) through (v) hereof, be accompanied

by an instruction to suspend the use of the Prospectus until the requisite changes have been made) as promptly as reasonably possible

(and, in the case of (i)(A) below, not less than one (1) Trading Day prior to such filing) and (if requested by any such Person) confirm

such notice in writing no later than one (1) Trading Day following the day (i)(A) when a Prospectus or any Prospectus supplement or post-effective

amendment to a Registration Statement is proposed to be filed, (B) when the Commission notifies the Company whether there will be a “review”

of such Registration Statement and whenever the Commission comments in writing on such Registration Statement, and (C) with respect to

a Registration Statement or any post-effective amendment, when the same has become effective, (ii) of any request by the Commission or

any other federal or state governmental authority for amendments or supplements to a Registration Statement or Prospectus or for additional

information, (iii) of the issuance by the Commission or any other federal or state governmental authority of any stop order suspending

the effectiveness of a Registration Statement covering any or all of the Registrable Securities or the initiation of any Proceedings

for that purpose, (iv) of the receipt by the Company of any notification with respect to the suspension of the qualification or exemption

from qualification of any of the Registrable Securities for sale in any jurisdiction, or the initiation or threatening of any Proceeding

for such purpose, and (v) of the occurrence of any event or passage of time that makes the financial statements included in a Registration

Statement ineligible for inclusion therein or any statement made in a Registration Statement or Prospectus or any document incorporated

or deemed to be incorporated therein by reference untrue in any material respect or that requires any revisions to a Registration Statement,

Prospectus or other documents so that, in the case of a Registration Statement or the Prospectus, as the case may be, it will not contain

any untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary to make the statements

therein, in light of the circumstances under which they were made, not misleading.

8

(e)

Use commercially reasonable efforts to avoid the issuance of, or, if issued, obtain the withdrawal of (i) any order stopping or suspending

the effectiveness of a Registration Statement, or (ii) any suspension of the qualification (or exemption from qualification) of any of

the Registrable Securities for sale in any jurisdiction, at the earliest practicable moment.

(f)

Furnish to each Holder, without charge, at least one conformed copy of each such Registration Statement and each amendment thereto, including

financial statements and schedules, all documents incorporated or deemed to be incorporated therein by reference to the extent requested

by such Person, and all exhibits to the extent requested by such Person (including those previously furnished or incorporated by reference)

promptly after the filing of such documents with the Commission, provided that any such item which is available on the EDGAR system (or

successor thereto) need not be furnished in physical form.

(g)

Subject to the terms of this Agreement, the Company hereby consents to the use of such Prospectus and each amendment or supplement thereto

by each of the selling Holders in connection with the offering and sale of the Registrable Securities covered by such Prospectus and

any amendment or supplement thereto, except after the giving of any notice pursuant to Section 3(d).

(h)

Prior to any resale of Registrable Securities by a Holder, use its commercially reasonable efforts to register or qualify or cooperate

with the selling Holders in connection with the registration or qualification (or exemption from the registration or qualification) of

such Registrable Securities for the resale by the Holder under the securities or Blue Sky laws of such jurisdictions within the United

States as any Holder reasonably requests in writing, to keep each registration or qualification (or exemption therefrom) effective during

the Effectiveness Period and to do any and all other acts or things reasonably necessary to enable the disposition in such jurisdictions

of the Registrable Securities covered by each Registration Statement, provided that the Company shall not be required to qualify generally

to do business in any jurisdiction where it is not then so qualified, subject the Company to any material tax in any such jurisdiction

where it is not then so subject or file a general consent to service of process in any such jurisdiction.

(i)

If requested by a Holder, cooperate with such Holder to facilitate the timely preparation and delivery of certificates representing Registrable

Securities to be delivered to a transferee pursuant to a Registration Statement, which certificates shall be free, to the extent permitted

by the Purchase Agreement and applicable law, of all restrictive legends, and to enable such Registrable Securities to be in such denominations

and registered in such names as any such Holder may request.

9

(j)

Upon the occurrence of any event contemplated by Section 3(d), as promptly as reasonably possible under the circumstances taking into

account the Company’s good faith assessment of any adverse consequences to the Company and its stockholders of the premature disclosure

of such event, prepare a supplement or amendment, including a post-effective amendment, to the affected Registration Statements or a

supplement to any related Prospectus or any document incorporated or deemed to be incorporated therein by reference, and file any other

required document so that, as thereafter delivered, neither a Registration Statement nor such Prospectus will contain an untrue statement

of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein, in light

of the circumstances under which they were made, not misleading. If the Company notifies

the Holders in accordance with clauses (iii) through (v) of Section 3(d) above to suspend the use of any Prospectus until the requisite

changes to such Prospectus have been made, then the Holders shall suspend use of such Prospectus. The Company will use commercially reasonable

efforts to ensure that the use of the Prospectus may be resumed as promptly as is practicable. The Company shall be entitled to exercise

its right under this Section 3(j) to suspend the availability of a Registration Statement and Prospectus, subject to the payment of partial

liquidated damages otherwise required pursuant to Section 2(d), for a period not to exceed 60 calendar days (which need not be consecutive

days) in any 12-month period.

(k)

Otherwise use commercially reasonable efforts to comply with all applicable rules and regulations of the Commission under the Securities

Act and the Exchange Act, including, without limitation, Rule 172 under the Securities Act, file any final Prospectus, including any

supplement or amendment thereof, with the Commission pursuant to Rule 424 under the Securities Act, promptly inform the Holders in writing

if, at any time during the Effectiveness Period, the Company does not satisfy the conditions specified in Rule 172 and, as a result thereof,

the Holders are required to deliver a Prospectus in connection with any disposition of Registrable Securities and take such other actions

as may be reasonably necessary to facilitate the registration of the Registrable Securities hereunder.

(l)

The Company shall use commercially reasonable efforts to maintain eligibility for use of Form S-3 (or any successor form thereto) for

the registration of the resale of Registrable Securities.

(m)

The Company may require each selling Holder to furnish to the Company a certified statement as to the number of shares of Common Stock

beneficially owned by such Holder and, if required by the Commission, the natural persons thereof that have voting and dispositive control

over the shares. During any periods that the Company is unable to meet its obligations hereunder with respect to the registration of

the Registrable Securities solely because any Holder fails to furnish such information within three Trading Days of the Company’s

request, any liquidated damages that are accruing at such time as to such Holder only shall be tolled and any Event that may otherwise

occur solely because of such delay shall be suspended as to such Holder only, until such information is delivered to the Company.

10

4.

Registration Expenses. All fees and expenses incident to the performance of or compliance with, this Agreement by the Company

shall be borne by the Company whether or not any Registrable Securities are sold pursuant to a Registration Statement. The fees and expenses

referred to in the foregoing sentence shall include, without limitation, (i) all registration and filing fees (including, without limitation,

fees and expenses) (A) with respect to filings made with the Commission, (B) with respect to filings required to be made with any Trading

Market on which the Common Stock is then listed for trading, and (C) in compliance with applicable state securities or Blue Sky laws

reasonably agreed to by the Company in writing (including, without limitation, fees and disbursements of counsel for the Company in connection

with Blue Sky qualifications or exemptions of the Registrable Securities), (ii) printing expenses (including, without limitation, expenses

of printing certificates for Registrable Securities), (iii) messenger, telephone and delivery expenses, (iv) fees and disbursements of

counsel and independent registered public accountants for the Company, (v) Securities Act liability insurance, if the Company so desires

such insurance, and (vi) fees and expenses of all other Persons retained by the Company in connection with the consummation of the transactions

contemplated by this Agreement. In addition, the Company shall be responsible for all of its internal expenses incurred in connection

with the consummation of the transactions contemplated by this Agreement (including, without limitation, all salaries and expenses of

its officers and employees performing legal or accounting duties), the expense of any annual audit and the fees and expenses incurred

in connection with the listing of the Registrable Securities on any securities exchange as required hereunder. In no event shall the

Company be responsible for any broker or similar commissions of any Holder or, except to the extent provided for in the Transaction Documents,

any legal fees or other costs of the Holders.

5.

Indemnification.

(a)

Indemnification by the Company. The Company shall, notwithstanding any termination of this Agreement, indemnify and hold harmless

each Holder, the officers, directors, members, partners, agents, brokers (including brokers who offer and sell Registrable Securities

as principal as a result of a pledge or any failure to perform under a margin call of Common Stock), investment advisors and employees

(and any other Persons with a functionally equivalent role of a Person holding such titles, notwithstanding a lack of such title or any

other title) of each of them, each Person who controls any such Holder (within the meaning of Section 15 of the Securities Act or Section

20 of the Exchange Act) and the officers, directors, members, stockholders, partners, agents and employees (and any other Persons with

a functionally equivalent role of a Person holding such titles, notwithstanding a lack of such title or any other title) of each such

controlling Person, to the fullest extent permitted by applicable law, from and against any and all losses, claims, damages, liabilities,

costs (including, without limitation, reasonable attorneys’ fees) and expenses (collectively, “Losses”), as

incurred, arising out of or relating to (1) any untrue or alleged untrue statement of a material fact contained in a Registration Statement,

any Prospectus or any form of prospectus or in any amendment or supplement thereto or in any preliminary prospectus, or arising out of

or relating to any omission or alleged omission of a material fact required to be stated therein or necessary to make the statements

therein (in the case of any Prospectus or supplement thereto, in light of the circumstances under which they were made) not misleading

or (2) any violation or alleged violation by the Company of the Securities Act, the Exchange Act or any state securities law, or any

rule or regulation thereunder, in connection with the performance of its obligations under this Agreement, except to the extent, but

only to the extent, that (i) such untrue statements or omissions are based solely upon information regarding such Holder furnished in

writing to the Company by such Holder expressly for use therein, or to the extent that such information relates to such Holder or such

Holder’s proposed method of distribution of Registrable Securities and was reviewed and expressly approved in writing by such Holder

expressly for use in a Registration Statement, such Prospectus or in any amendment or supplement thereto (it being understood that the

Holder has approved Annex A hereto for this purpose) or (ii) in the case of an occurrence of an event of the type specified in Section

3(d)(iii)-(v), the use by such Holder of an outdated, defective or otherwise unavailable Prospectus after the Company has notified such

Holder in writing that the Prospectus is outdated, defective or otherwise unavailable for use by such Holder and prior to the receipt

by such Holder of the Advice contemplated in Section 6(c). The Company shall notify the Holders promptly of the institution, threat or

assertion of any Proceeding arising from or in connection with the transactions contemplated by this Agreement of which the Company is

aware. Such indemnity shall remain in full force and effect regardless of any investigation made by or on behalf of such indemnified

person and shall survive the transfer of any Registrable Securities by any of the Holders in accordance with Section 6(f).

11

(b)

Indemnification by Holders. Each Holder shall, severally and not jointly, indemnify and hold harmless the Company, its directors,

officers, agents and employees, each Person who controls the Company (within the meaning of Section 15 of the Securities Act and Section

20 of the Exchange Act), and the directors, officers, agents or employees of such controlling Persons, to the fullest extent permitted

by applicable law, from and against all Losses, as incurred, to the extent arising out of or based solely upon: any untrue or alleged

untrue statement of a material fact contained in any Registration Statement, any Prospectus, or in any amendment or supplement thereto

or in any preliminary prospectus, or arising out of or relating to any omission or alleged omission of a material fact required to be

stated therein or necessary to make the statements therein (in the case of any Prospectus or supplement thereto, in light of the circumstances

under which they were made) not misleading (i) to the extent, but only to the extent, that such untrue statement or omission is contained

in any information so furnished in writing by such Holder to the Company expressly for inclusion in such Registration Statement or such

Prospectus, (ii) to the extent, but only to the extent, that such information relates to such Holder’s information provided in

the Selling Stockholder Questionnaire or the proposed method of distribution of Registrable Securities and was reviewed and expressly

approved in writing by such Holder expressly for use in a Registration Statement (it being understood that the Holder has approved Annex

A hereto for this purpose), such Prospectus or in any amendment or supplement thereto or (iii) in the case of an occurrence of an event

of the type specified in Section 3(d)(iii)-(v), to the extent, but only to the extent, related to the use by such Holder of an outdated,

defective or otherwise unavailable Prospectus after the Company has notified such Holder in writing that the Prospectus is outdated,

defective or otherwise unavailable and prior to the receipt by such Holder of the Advice contemplated in Section 6(c). In no event shall

the liability of a selling Holder be greater in amount than the dollar amount of the net proceeds received by such Holder upon the sale

of the Registrable Securities giving rise to such indemnification obligation.

(c)

Conduct of Indemnification Proceedings. If any Proceeding shall be brought or asserted against any Person entitled to indemnity

hereunder (an “Indemnified Party”), such Indemnified Party shall promptly notify the Person from whom indemnity is

sought (the “Indemnifying Party”) in writing, and the Indemnifying Party shall have the right to assume the defense

thereof, including the employment of counsel reasonably satisfactory to the Indemnified Party and the payment of all reasonable fees

and expenses incurred in connection with defense thereof, provided that the failure of any Indemnified Party to give such notice shall

not relieve the Indemnifying Party of its obligations or liabilities pursuant to this Agreement, except (and only) to the extent that

it shall be finally determined by a court of competent jurisdiction (which determination is not subject to appeal or further review)

that such failure shall have materially and adversely prejudiced the Indemnifying Party.

12

An

Indemnified Party shall have the right to employ separate counsel in any such Proceeding and to participate in the defense thereof, but

the fees and expenses of such counsel shall be at the expense of such Indemnified Party or Parties unless: (1) the Indemnifying Party

has agreed in writing to pay such fees and expenses, (2) the Indemnifying Party shall have failed promptly to assume the defense of such

Proceeding and to employ counsel reasonably satisfactory to such Indemnified Party in any such Proceeding, or (3) the named parties to

any such Proceeding (including any impleaded parties) include both such Indemnified Party and the Indemnifying Party, and counsel to

the Indemnified Party shall reasonably believe that a material conflict of interest is likely to exist if the same counsel were to represent

such Indemnified Party and the Indemnifying Party (in which case, if such Indemnified Party notifies the Indemnifying Party in writing

that it elects to employ separate counsel at the expense of the Indemnifying Party, the Indemnifying Party shall not have the right to

assume the defense thereof and the reasonable fees and expenses of no more than one separate counsel shall be at the expense of the Indemnifying

Party). The Indemnifying Party shall not be liable for any settlement of any such Proceeding effected without its written consent, which

consent shall not be unreasonably withheld or delayed. No Indemnifying Party shall, without the prior written consent of the Indemnified

Party, effect any settlement of any pending Proceeding in respect of which any Indemnified Party is a party, unless such settlement includes

an unconditional release of such Indemnified Party from all liability on claims that are the subject matter of such Proceeding.

Subject

to the terms of this Agreement, all reasonable fees and expenses of the Indemnified Party (including reasonable fees and expenses to

the extent incurred in connection with investigating or preparing to defend such Proceeding in a manner not inconsistent with this Section)

shall be paid to the Indemnified Party, as incurred, within ten Trading Days of written notice thereof to the Indemnifying Party, provided

that the Indemnified Party shall promptly reimburse the Indemnifying Party for that portion of such fees and expenses applicable to such

actions for which such Indemnified Party is finally determined by a court of competent jurisdiction (which determination is not subject

to appeal or further review) not to be entitled to indemnification hereunder.

(d)

Contribution. If the indemnification under Section 5(a) or 5(b) is unavailable to an Indemnified Party or insufficient to hold

an Indemnified Party harmless for any Losses, then each Indemnifying Party shall contribute to the amount paid or payable by such Indemnified

Party, in such proportion as is appropriate to reflect the relative fault of the Indemnifying Party and Indemnified Party in connection

with the actions, statements or omissions that resulted in such Losses as well as any other relevant equitable considerations. The relative

fault of such Indemnifying Party and Indemnified Party shall be determined by reference to, among other things, whether any action in

question, including any untrue or alleged untrue statement of a material fact or omission or alleged omission of a material fact, has

been taken or made by, or relates to information supplied by, such Indemnifying Party or Indemnified Party, and the parties’ relative

intent, knowledge, access to information and opportunity to correct or prevent such action, statement or omission. The amount paid or

payable by a party as a result of any Losses shall be deemed to include, subject to the limitations set forth in this Agreement, any

reasonable attorneys’ or other fees or expenses incurred by such party in connection with any Proceeding to the extent such party

would have been indemnified for such fees or expenses if the indemnification provided for in this Section was available to such party

in accordance with its terms.

13

The

parties hereto agree that it would not be just and equitable if contribution pursuant to this Section 5(d) were determined by pro rata

allocation or by any other method of allocation that does not take into account the equitable considerations referred to in the immediately

preceding paragraph. In no event shall the contribution obligation of a Holder of Registrable Securities be greater in amount than the

dollar amount of the net proceeds received by such Holder from the sale of Registrable Securities subject to the Proceeding exceeds the

amount of any damages such Holder has otherwise been required to pay by reason of such untrue or alleged untrue statement or omission

or alleged omission).

The

indemnity and contribution agreements contained in this Section 5 are in addition to any liability that the Indemnifying Parties may

have to the Indemnified Parties.

6.

Miscellaneous.

(a)

Remedies. In the event of a breach by the Company or by a Holder of any of their respective obligations under this Agreement,

each Holder or the Company, as the case may be, in addition to being entitled to exercise all rights granted by law and under this Agreement,

including recovery of damages, shall be entitled to specific performance of its rights under this Agreement. Each of the Company and

each Holder agrees that monetary damages would not provide adequate compensation for any losses incurred by reason of a breach by it

of any of the provisions of this Agreement and hereby further agrees that, in the event of any action for specific performance in respect

of such breach, it shall not assert or shall waive the defense that a remedy at law would be adequate.

(b)

No Piggyback on Registrations; Prohibition on Filing Other Registration Statements. Except as set forth on Schedule 6(b)

attached hereto, and the shares of Common Stock issuable upon exercise of the warrants issued to the Placement Agent in the transactions

contemplated by the Purchase Agreement, neither the Company nor any of its security holders (other than the Holders in such capacity

pursuant hereto) may include securities of the Company in any Registration Statements other than the Registrable Securities. The Company

shall not file any other registration statements other than a Registration Statement during the prohibition period set forth in Section

4.11(a) of the Purchase Agreement.

(c)

Discontinued Disposition. By its acquisition of Registrable Securities, each Holder agrees that, upon receipt of a notice from

the Company of the occurrence of any event of the kind described in Section 3(d)(iii) through (vi), such Holder will forthwith discontinue

disposition of such Registrable Securities under a Registration Statement until it is advised in writing (the “Advice”)

by the Company that the use of the applicable Prospectus (as it may have been supplemented or amended) may be resumed. The Company will

use commercially reasonable efforts to ensure that the use of the Prospectus may be resumed as promptly as is practicable. The Company

agrees and acknowledges that any periods during which the Holder is required to discontinue the disposition of the Registrable Securities

hereunder shall be subject to the provisions of Section 2(d).

14

(d)

Amendments and Waivers. The provisions of this Agreement, including the provisions of this sentence, may not be amended, modified

or supplemented, and waivers or consents to departures from the provisions hereof may not be given, unless the same shall be in writing

and signed by the Company and the Holders of 50.1% or more of the then outstanding Registrable Securities (for purposes of clarification,

this includes any Registrable Securities issuable upon exercise or conversion of any Security), provided that, if any amendment, modification

or waiver disproportionately and adversely impacts a Holder (or group of Holders), the consent of such disproportionately impacted Holder

(or group of Holders) shall be required. If a Registration Statement does not register all of the Registrable Securities pursuant to

a waiver or amendment done in compliance with the previous sentence, then the number of Registrable Securities to be registered for each

Holder shall be reduced pro rata among all Holders and each Holder shall have the right to designate which of its Registrable Securities

shall be omitted from such Registration Statement. Notwithstanding the foregoing, a waiver or consent to depart from the provisions hereof

with respect to a matter that relates exclusively to the rights of a Holder or some Holders and that does not directly or indirectly

affect the rights of other Holders may be given only by such Holder or Holders of all of the Registrable Securities to which such waiver

or consent relates; provided, however, that the provisions of this sentence may not be amended, modified, or supplemented

except in accordance with the provisions of the first sentence of this Section 6(d). No consideration shall be offered or paid to any

Person to amend or consent to a waiver or modification of any provision of this Agreement unless the same consideration also is offered

to all of the parties to this Agreement.

(e)

Notices. Any and all notices or other communications or deliveries required or permitted to be provided hereunder shall be delivered

as set forth in the Purchase Agreement.

(f)

Successors and Assigns. This Agreement shall inure to the benefit of and be binding upon the successors and permitted assigns

of each of the parties and shall inure to the benefit of each Holder. The Company may not assign (except by merger) its rights or obligations

hereunder without the prior written consent of all of the Holders of the then outstanding Registrable Securities. Each Holder may assign

their respective rights hereunder in the manner and to the Persons as permitted under Section 5.7 of the Purchase Agreement.

(g)

No Inconsistent Agreements. Neither the Company nor any of its Subsidiaries has entered, as of the date hereof, nor shall the

Company or any of its Subsidiaries, on or after the date of this Agreement, enter into any agreement with respect to its securities,

that would have the effect of impairing the rights granted to the Holders in this Agreement or otherwise conflicts with the provisions

hereof. Except as set forth on Schedule 6(g), neither the Company nor any of its Subsidiaries has previously entered into any

agreement granting any registration rights with respect to any of its securities to any Person that have not been satisfied in full.

15

(h)

Execution and Counterparts. This Agreement may be executed in two or more counterparts, all of which when taken together shall

be considered one and the same agreement and shall become effective when counterparts have been signed by each party and delivered to

the other party, it being understood that both parties need not sign the same counterpart. In the event that any signature is delivered

by e-mail delivery of a “.pdf” format data file or any electronic signature complying with the U.S. federal ESIGN Act of

2000 (e.g., www.docusign.com), such signature shall create a valid and binding obligation of the party executing (or on whose behalf

such signature is executed) with the same force and effect as if such “.pdf” signature page were an original thereof.

(i)

Governing Law. All questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be

determined in accordance with the provisions of the Purchase Agreement.

(j)

Cumulative Remedies. The remedies provided herein are cumulative and not exclusive of any other remedies provided by law.

(k)

Severability. If any term, provision, covenant or restriction of this Agreement is held by a court of competent jurisdiction to

be invalid, illegal, void or unenforceable, the remainder of the terms, provisions, covenants and restrictions set forth herein shall

remain in full force and effect and shall in no way be affected, impaired or invalidated, and the parties hereto shall use their commercially

reasonable efforts to find and employ an alternative means to achieve the same or substantially the same result as that contemplated

by such term, provision, covenant or restriction. It is hereby stipulated and declared to be the intention of the parties that they would

have executed the remaining terms, provisions, covenants and restrictions without including any of such that may be hereafter declared

invalid, illegal, void or unenforceable.

(l)

Headings. The headings in this Agreement are for convenience only, do not constitute a part of the Agreement and shall not be

deemed to limit or affect any of the provisions hereof.

(m)

Independent Nature of Holders’ Obligations and Rights. The obligations of each Holder hereunder are several and not joint

with the obligations of any other Holder hereunder, and no Holder shall be responsible in any way for the performance of the obligations

of any other Holder hereunder. Nothing contained herein or in any other agreement or document delivered at any closing, and no action

taken by any Holder pursuant hereto or thereto, shall be deemed to constitute the Holders as a partnership, an association, a joint venture

or any other kind of group or entity, or create a presumption that the Holders are in any way acting in concert or as a group or entity

with respect to such obligations or the transactions contemplated by this Agreement or any other matters, and the Company acknowledges

that the Holders are not acting in concert or as a group, and the Company shall not assert any such claim, with respect to such obligations

or transactions. Each Holder shall be entitled to protect and enforce its rights, including without limitation the rights arising out

of this Agreement, and it shall not be necessary for any other Holder to be joined as an additional party in any proceeding for such

purpose. The use of a single agreement with respect to the obligations of the Company contained was solely in the control of the Company,

not the action or decision of any Holder, and was done solely for the convenience of the Company and not because it was required or requested

to do so by any Holder. It is expressly understood and agreed that each provision contained in this Agreement is between the Company

and a Holder, solely, and not between the Company and the Holders collectively and not between and among Holders.

********************

(Signature

Pages Follow)

16

IN

WITNESS WHEREOF, the parties have executed this Registration Rights Agreement as of the date first written above.

gt

biopharma, inc.

By:

Name:

Title:

[SIGNATURE

PAGE OF HOLDERS FOLLOWS]

[SIGNATURE

PAGE OF HOLDERS TO gtbp RRA]

Name

of Holder: __________________________

Signature

of Authorized Signatory of Holder: __________________________

Name

of Authorized Signatory: _________________________

Title

of Authorized Signatory: __________________________

[SIGNATURE

PAGES CONTINUE]

Annex

A

Plan

of Distribution

Each

Selling Stockholder (the “Selling Stockholders”) of the securities and any of their pledgees, assignees and successors-in-interest

may, from time to time, sell any or all of their securities covered hereby on the Nasdaq Capital Market or any other stock exchange,

market or trading facility on which the securities are traded or in private transactions. These sales may be at fixed or negotiated prices.

A Selling Stockholder may use any one or more of the following methods when selling securities:

●

ordinary brokerage transactions and transactions in which the

broker-dealer solicits purchasers;

●

block trades in which the broker-dealer will attempt to sell

the securities as agent but may position and resell a portion of the block as principal to facilitate the transaction;

●

purchases by a broker-dealer as principal and resale by the

broker-dealer for its account;

●

an exchange distribution in accordance with the rules of the

applicable exchange;

●

privately negotiated transactions;

●

settlement of short sales effected after the effective date

of the registration statement of which this prospectus is a part;

●

in transactions through broker-dealers that agree with the

Selling Stockholders to sell a specified number of such securities at a stipulated price per security;

●

through the writing or settlement of options or other hedging

transactions, whether through an options exchange or otherwise;

●

a combination of any such methods of sale; or

●

any other method permitted pursuant to applicable law.

The

Selling Stockholders may also sell securities under Rule 144 or any other exemption from registration under the Securities Act of 1933,

as amended (the “Securities Act”), if available, rather than under this prospectus.

Broker-dealers

engaged by the Selling Stockholders may arrange for other brokers-dealers to participate in sales. Broker-dealers may receive commissions

or discounts from the Selling Stockholders (or, if any broker-dealer acts as agent for the purchaser of securities, from the purchaser)

in amounts to be negotiated, but, except as set forth in a supplement to this Prospectus, in the case of an agency transaction not in

excess of a customary brokerage commission in compliance with FINRA Rule 2121; and in the case of a principal transaction a markup or

markdown in compliance with FINRA Rule 2121.

In

connection with the sale of the securities or interests therein, the Selling Stockholders may enter into hedging transactions with broker-dealers

or other financial institutions, which may in turn engage in short sales of the securities in the course of hedging the positions they

assume. The Selling Stockholders may also sell securities short and deliver these securities to close out their short positions, or loan

or pledge the securities to broker-dealers that in turn may sell these securities. The Selling Stockholders may also enter into option

or other transactions with broker-dealers or other financial institutions or create one or more derivative securities which require the

delivery to such broker-dealer or other financial institution of securities offered by this prospectus, which securities such broker-dealer

or other financial institution may resell pursuant to this prospectus (as supplemented or amended to reflect such transaction).

The

Selling Stockholders and any broker-dealers or agents that are involved in selling the securities may be deemed to be “underwriters”

within the meaning of the Securities Act in connection with such sales. In such event, any commissions received by such broker-dealers

or agents and any profit on the resale of the securities purchased by them may be deemed to be underwriting commissions or discounts

under the Securities Act. Each Selling Stockholder has informed the Company that it does not have any written or oral agreement or understanding,

directly or indirectly, with any person to distribute the securities.

The

Company is required to pay certain fees and expenses incurred by the Company incident to the registration of the securities. The Company

has agreed to indemnify the Selling Stockholders against certain losses, claims, damages and liabilities, including liabilities under

the Securities Act.

We

agreed to keep this prospectus effective until the earlier of (i) the date on which the securities may be resold by the Selling Stockholders

without registration and without regard to any volume or manner-of-sale limitations by reason of Rule 144, without the requirement for

the Company to be in compliance with the current public information under Rule 144 under the Securities Act or any other rule of similar

effect or (ii) all of the securities have been sold pursuant to this prospectus or Rule 144 under the Securities Act or any other rule

of similar effect. The resale securities will be sold only through registered or licensed brokers or dealers if required under applicable

state securities laws. In addition, in certain states, the resale securities covered hereby may not be sold unless they have been registered

or qualified for sale in the applicable state or an exemption from the registration or qualification requirement is available and is

complied with.

Under

applicable rules and regulations under the Exchange Act, any person engaged in the distribution of the resale securities may not simultaneously

engage in market making activities with respect to the common stock for the applicable restricted period, as defined in Regulation M,

prior to the commencement of the distribution. In addition, the Selling Stockholders will be subject to applicable provisions of the

Exchange Act and the rules and regulations thereunder, including Regulation M, which may limit the timing of purchases and sales of the

common stock by the Selling Stockholders or any other person. We will make copies of this prospectus available to the Selling Stockholders

and have informed them of the need to deliver a copy of this prospectus to each purchaser at or prior to the time of the sale (including

by compliance with Rule 172 under the Securities Act).

2

Annex

B

SELLING

STOCKHOLDERS

The

common stock being offered by the selling stockholders are those previously issued to the selling stockholders, and those issuable to

the selling stockholders, upon conversion of shares of preferred stock and exercise of the warrants. For additional information regarding

the issuances of those shares of preferred stock and warrants, see “Private Placement of Shares of Preferred Stock and Warrants”

above. We are registering the shares of common stock in order to permit the selling stockholders to offer the shares for resale from

time to time. Except for the ownership of the shares of capital stock and warrants, the selling stockholders have not had any material

relationship with us within the past three years.

The

table below lists the selling stockholders and other information regarding the beneficial ownership of the shares of common stock by

each of the selling stockholders. The second column lists the number of shares of common stock beneficially owned by each selling stockholder,

based on its ownership of the shares of capital stock and warrants, as of ________, 2026, assuming conversion of the shares of preferred

stock and exercise of the warrants held by the selling stockholders on that date, without regard to any limitations on conversion or

exercise.

The

third column lists the shares of common stock being offered by this prospectus by the selling stockholders.

In

accordance with the terms of a registration rights agreement with the selling stockholders, this prospectus generally covers the resale

of the sum of (i) the number of shares of common stock underlying the shares of preferred stock issued to the selling stockholders in

the “Private Placement of Shares of Preferred Stock and Warrants” described above, determined as if the outstanding shares

of preferred stock were converted in full, and (ii) the maximum number of shares of common stock issuable upon exercise of the related

warrants, determined as if the outstanding warrants were exercised in full, each determined as of the trading day immediately preceding

the applicable date of determination and all subject to adjustment as provided in the registration right agreement, without regard to

any limitations on the conversion of the shares of preferred stock or exercise of the warrants. The fourth column assumes the sale of

all of the shares offered by the selling stockholders pursuant to this prospectus.

Under

the terms of the shares of preferred stock and the warrants, a selling stockholder may not convert or exercise any such security, as

applicable, to the extent such conversion or exercise would cause such selling stockholder, together with its affiliates and attribution

parties, to beneficially own a number of shares of common stock which would exceed [4.99% or] 9.99%[, as applicable,] of our then outstanding

common stock following such conversion or exercise, excluding for purposes of such determination shares of common stock issuable upon

conversion of such shares of preferred stock which have not been converted, and exercise of such warrants which have not been exercised.

The number of shares in the second and fourth columns do not reflect this limitation. The selling stockholders may sell all, some or

none of their shares in this offering. See "Plan of Distribution."

Name of Selling Stockholder

Number

of shares of Common Stock Owned Prior to Offering

Maximum

Number of shares of Common Stock to be Sold Pursuant to this Prospectus

Number

of shares of Common Stock Owned After Offering

3

Annex

C

gt

biopharma, inc.

Selling

Stockholder Notice and Questionnaire

The

undersigned beneficial owner of common stock (the “Registrable Securities”) of GT Biopharma, Inc., a Delaware corporation

(the “Company”), understands that the Company has filed or intends to file with the Securities and Exchange Commission

(the “Commission”) a registration statement (the “Registration Statement”) for the registration

and resale under Rule 415 of the Securities Act of 1933, as amended (the “Securities Act”), of the Registrable Securities,

in accordance with the terms of the Registration Rights Agreement (the “Registration Rights Agreement”) to which this

document is annexed. A copy of the Registration Rights Agreement is available from the Company upon request at the address set forth

below. All capitalized terms not otherwise defined herein shall have the meanings ascribed thereto in the Registration Rights Agreement.

In

order to sell or otherwise dispose of any Registrable Securities pursuant to the Registration Statement, a holder of Registrable Securities

generally will be required to be named as a selling stockholder in the related prospectus or a supplement thereto (as so supplemented,

the “Prospectus”), deliver the Prospectus to purchasers of Registrable Securities (including pursuant to Rule 172

under the Securities Act) and be bound by the provisions of the Registration Rights Agreement (including certain indemnification provisions,

as described therein). Holders must complete and deliver this Notice and Questionnaire in order to be named as selling stockholders in

the Prospectus.

Certain

legal consequences arise from being named as a selling stockholder in the Registration Statement and the related prospectus. Accordingly,

holders and beneficial owners of Registrable Securities are advised to consult their own securities law counsel regarding the consequences

of being named or not being named as a selling stockholder in the Registration Statement and the related prospectus.

NOTICE

The

undersigned beneficial owner (the “Selling Stockholder”) of Registrable Securities hereby elects to include the Registrable

Securities owned by it in the Registration Statement.

1

The

undersigned hereby provides the following information to the Company and represents and warrants that such information is accurate:

QUESTIONNAIRE

1.

Name.

(a)

Full Legal Name of Selling

Stockholder

(b)

Full Legal Name of Registered Holder (if not

the same as (a) above) through which Registrable Securities are held:

(c)

Full Legal Name of Natural Control Person

(which means a natural person who directly or indirectly alone or with others has power to vote or dispose of the securities covered

by this Questionnaire):

2.

Address for Notices to Selling Stockholder:

Telephone:

E-Mail:

Contact Person:

3.

Broker-Dealer Status:

(a)

Are you a broker-dealer?

Yes ☐

No ☐

(b)

If “yes” to Section

3(a), did you receive your Registrable Securities as compensation for investment banking services to the Company?

Yes ☐

No ☐

Note:

If “no” to Section

3(b), the Commission’s staff has indicated that you should be identified as an underwriter in the Registration Statement.

2

(c)

Are you an affiliate of a broker-dealer?

Yes ☐

No ☐

(d)

If you are an affiliate of a broker-dealer,

do you certify that you purchased the Registrable Securities in the ordinary course of business, and at the time of the purchase of

the Registrable Securities to be resold, you had no agreements or understandings, directly or indirectly, with any person to distribute

the Registrable Securities?

Yes ☐

No ☐

Note:

If “no” to Section

3(d), the Commission’s staff has indicated that you should be identified as an underwriter in the Registration Statement.

4.

Beneficial Ownership of Securities of the Company

Owned by the Selling Stockholder.

Except

as set forth below in this Item 4, the undersigned is not the beneficial or registered owner of any securities of the Company other than

the securities issuable pursuant to the Purchase Agreement.

(a)

Type and Amount of other

securities beneficially owned by the Selling Stockholder:

5.

Relationships with the Company:

Except

as set forth below, neither the undersigned nor any of its affiliates, officers, directors or principal equity holders (owners of 5%

of more of the equity securities of the undersigned) has held any position or office or has had any other material relationship with

the Company (or its predecessors or affiliates) during the past three years.

State any exceptions

here:

3

6.

Plan of Distribution.

The

undersigned has reviewed the form of Plan of Distribution attached as Annex A to the Registration Rights Agreement, and hereby confirms

that, except as set forth below, the information contained therein regarding the undersigned and its plan of distribution is correct

and complete.

State any exceptions

here:

The

undersigned agrees to promptly notify the Company of any material inaccuracies or changes in the information provided herein that may

occur subsequent to the date hereof at any time while the Registration Statement remains effective; provided, that the undersigned shall

not be required to notify the Company of any changes to the number of securities held or owned by the undersigned or its affiliates.

By

signing below, the undersigned consents to the disclosure of the information contained herein in its answers to Items 1 through 6 and

the inclusion of such information in the Registration Statement and the related prospectus and any amendments or supplements thereto.

The undersigned understands that such information will be relied upon by the Company in connection with the preparation or amendment

of the Registration Statement and the related prospectus and any amendments or supplements thereto.

By

signing below, the undersigned acknowledges that it understands its obligation to comply, and agrees that it will comply, with the provisions

of the Exchange Act and the rules and regulations thereunder, particularly Regulation M in connection with any offering of Registrable

Securities pursuant to the Registration Statement. The undersigned also acknowledges that it understands that the answers to this Questionnaire

are furnished for use in connection with Registration Statements filed pursuant to the Registration Rights Agreement and any amendments

or supplements thereto filed with the Commission pursuant to the Securities Act.

The

undersigned hereby acknowledges and is advised of the following Interpretation A.65 of the July 1997 SEC Manual of Publicly Available

Telephone Interpretations regarding short selling:

“An

Issuer filed a Form S-3 registration statement for a secondary offering of common stock which is not yet effective. One of the selling

stockholders wanted to do a short sale of common stock “against the box” and cover the short sale with registered shares

after the effective date. The issuer was advised that the short sale could not be made before the registration statement become effective,

because the shares underlying the short sale are deemed to be sold at the time such sale is made. There would, therefore, be a violation

of Section 5 if the shares were effectively sold prior to the effective date.”

By

returning this Questionnaire, the undersigned will be deemed to be aware of the foregoing interpretation.

I

confirm that, to the best of my knowledge and belief, the foregoing statements (including without limitation the answers to this Questionnaire)

are correct.

4

IN

WITNESS WHEREOF the undersigned, by authority duly given, has caused this Notice and Questionnaire to be executed and delivered either

in person or by its duly authorized agent.

Date:

Beneficial Owner:

By:

Name:

Title:

PLEASE

EMAIL A .PDF COPY OF THE COMPLETED AND EXECUTED NOTICE AND QUESTIONNAIRE TO:

GT

Biopharma, Inc.

505 Montgomery Street, 10th Floor

San Francisco, CA 94111

Attention: Chief Executive Officer

E-Mail: mb@gtbiopharma.com

With

a copy to (which shall not constitute notice):

Baker

& Hostetler, LLP

1900 Avenue of the Stars, Suite 2700

Los

Angeles, CA 90067

Attention: JR Lanis

E-Mail:

jrlanis@bakerlaw.com

5

EX-10.3

EX-10.3

Filename: ex10-3.htm · Sequence: 7

Exhibit

10.3

TO:

The Purchasers of GT Biopharma, Inc., Series M 10% Convertible

Preferred Stock and Warrants

To

Whom It May Concern:

This

letter will confirm my agreement to vote all shares of GT Biopharma, Inc. (“GTBP”) voting stock over which I have

voting control in favor of any resolution presented to the shareholders of GTBP to approve the issuance, in the aggregate, of more than

19.99% of the number of shares of common stock of GTBP outstanding on the date of closing pursuant to that certain Securities Purchase

Agreement, dated September 14, 2026, among GTBP and the purchasers signatory thereto (the “Purchase Agreement”) and

the other agreements entered into in connection therewith or as otherwise may be required by the applicable rules and regulations of

the Nasdaq Stock Market LLC (or any successor entity). This agreement is given in consideration of, and as a condition to enter into

such Purchase Agreement and is not revocable by me.

This

letter is intended for the benefit of the parties hereto and their respective successors and permitted assigns and is not for the benefit

of, nor may any provision hereof be enforced by, any other Person.

By:

Name

of Shareholder:

Number

of voting shares over which I have voting control: _________________

EX-10.4

EX-10.4

Filename: ex10-4.htm · Sequence: 8

Exhibit

10.4

LOCK-UP

AGREEMENT

September

14, 2026

GT

Biopharma, Inc.

Re: Securities

Purchase Agreement, dated as of September 14, 2026 (the “Purchase Agreement”),

between GT Biopharma, Inc. (the “Company”) and the purchasers signatory thereto

(each, a “Purchaser” and, collectively, the “Purchasers”)

Ladies

and Gentlemen:

Defined

terms not otherwise defined in this letter agreement (the “Letter Agreement”) shall have the meanings set forth in

the Purchase Agreement. Pursuant to Section 2.2(a) of the Purchase Agreement and in satisfaction of a condition of the Company’s

obligations under the Purchase Agreement, the undersigned irrevocably agrees with the Company that, from the date hereof until thirty

(30) days after the later of (i) the Effective Date and (ii) the date that Shareholder Approval is obtained and deemed effective (such

period, the “Restriction Period”), the undersigned will not offer, sell, contract to sell, hypothecate, pledge or

otherwise dispose of (or enter into any transaction which is designed to, or might reasonably be expected to, result in the disposition

(whether by actual disposition or effective economic disposition due to cash settlement or otherwise) by the undersigned or any Affiliate

of the undersigned or any person in privity with the undersigned or any Affiliate of the undersigned), directly or indirectly, or establish

or increase a put equivalent position or liquidate or decrease a call equivalent position within the meaning of Section 16 of the Securities

Exchange Act of 1934, as amended (the “Exchange Act”), with respect to, any shares of Common Stock of the Company

or securities convertible, exchangeable or exercisable into, shares of Common Stock of the Company beneficially owned, held or hereafter

acquired by the undersigned (the “Securities”). Beneficial ownership shall be calculated in accordance with Section

13(d) of the Exchange Act. In order to enforce this covenant, the Company shall impose irrevocable stop-transfer instructions preventing

the transfer agent of the Company from effecting any actions in violation of this Letter Agreement.

Notwithstanding

the foregoing, and subject to the conditions below, the undersigned may transfer the Securities provided that (1) the Company receives

a signed lock-up letter agreement (in the form of this Letter Agreement) for the balance of the Restriction Period from each donee, trustee,

distributee, or transferee, as the case may be, prior to such transfer, (2) any such transfer shall not involve a disposition for value,

(3) such transfer is not required to be reported with the Securities and Exchange Commission in accordance with the Exchange Act and

no report of such transfer shall be made voluntarily, and (4) neither the undersigned nor any donee, trustee, distributee or transferee,

as the case may be, otherwise voluntarily effects any public filing or report regarding such transfers, with respect to transfer:

i)

as

a bona fide gift or gifts;

ii)

to

any immediate family member or to any trust for the direct or indirect benefit of the undersigned or the immediate family of the

undersigned (for purposes of this Letter Agreement, “immediate family” shall mean any relationship by blood, marriage

or adoption, not more remote than first cousin);

iii)

to

any corporation, partnership, limited liability company, or other business entity all of the equity holders of which consist of the

undersigned and/or the immediate family of the undersigned;

iv)

if

the undersigned is a corporation, partnership, limited liability company, trust or other business entity (a) to another corporation,

partnership, limited liability company, trust or other business entity that is an Affiliate of the undersigned or (b) in the form

of a distribution to limited partners, limited liability company members or stockholders of the undersigned;

v)

if

the undersigned is a trust, to the beneficiary of such trust;

vi)

by

will, other testamentary document or intestate succession to the legal representative, heir, beneficiary or a member of the immediate

family of the undersigned; or

vii)

of

securities purchased in open market transactions after the Closing Date.

In

addition, notwithstanding the foregoing, this Letter Agreement shall not restrict the delivery of shares of Common Stock to the undersigned

upon (i) exercise any options granted under any employee benefit plan of the Company; provided that any shares of Common Stock or Securities

acquired in connection with any such exercise will be subject to the restrictions set forth in this Letter Agreement, or (ii) the exercise

of warrants; provided that such shares of Common Stock delivered to the undersigned in connection with such exercise are subject to the

restrictions set forth in this Letter Agreement.

Furthermore,

the undersigned may enter into any new plan established in compliance with Rule 10b5-1 of the Exchange Act; provided that (i) such plan

may only be established if no public announcement or filing with the Securities and Exchange Commission, or other applicable regulatory

authority, is made in connection with the establishment of such plan during the Restriction Period and (ii) no sale of shares of Common

Stock are made pursuant to such plan during the Restriction Period.

The

undersigned acknowledges that the execution, delivery and performance of this Letter Agreement is a material inducement to the Company

to complete the transactions contemplated by the Purchase Agreement and the Company shall be entitled to specific performance of the

undersigned’s obligations hereunder. The undersigned hereby represents that the undersigned has the power and authority to execute,

deliver and perform this Letter Agreement, that the undersigned has received adequate consideration therefor and that the undersigned

will indirectly benefit from the closing of the transactions contemplated by the Purchase Agreement.

2

This

Letter Agreement may not be amended or otherwise modified in any respect without the written consent of each of the Company and the undersigned.

This Letter Agreement shall be construed and enforced in accordance with the laws of the State of New York without regard to the principles

of conflict of laws. The undersigned hereby irrevocably submits to the exclusive jurisdiction of the United States District Court sitting

in the Southern District of New York and the courts of the State of New York located in Manhattan, for the purposes of any suit, action

or proceeding arising out of or relating to this Letter Agreement, and hereby waives, and agrees not to assert in any such suit, action

or proceeding, any claim that (i) it is not personally subject to the jurisdiction of such court, (ii) the suit, action or proceeding

is brought in an inconvenient forum, or (iii) the venue of the suit, action or proceeding is improper. The undersigned hereby irrevocably

waives personal service of process and consents to process being served in any such suit, action or proceeding by receiving a copy thereof

sent to the Company at the address in effect for notices to it under the Purchase Agreement and agrees that such service shall constitute

good and sufficient service of process and notice thereof. The undersigned hereby waives any right to a trial by jury. Nothing contained

herein shall be deemed to limit in any way any right to serve process in any manner permitted by law. The undersigned agrees and understands

that this Letter Agreement does not intend to create any relationship between the undersigned and any Purchaser and that no Purchaser

is entitled to cast any votes on the matters herein contemplated and that no issuance or sale of the Securities is created or intended

by virtue of this Letter Agreement.

This

Letter Agreement shall be binding on successors and assigns of the undersigned with respect to the Securities and any such successor

or assign shall enter into a similar agreement for the benefit of the Company. This Letter Agreement is intended for the benefit of the

parties hereto and their respective successors and permitted assigns and is not for the benefit of, nor may any provision hereof be enforced

by, any other Person.

***

SIGNATURE PAGE FOLLOWS***

3

This

Letter Agreement may be executed in two or more counterparts, all of which when taken together may be considered one and the same agreement.

Signature

Print

Name

Position

in Company, if any

Address

for Notice:

_____________________________

_____________________________

_____________________________

Number

of shares of Common Stock

Number

of shares of Common Stock underlying subject to warrants, options, debentures or other convertible securities

By

signing below, the Company agrees to enforce the restrictions on transfer set forth in this Letter Agreement.

GT BIOPHARMA, INC.

By:

Name:

Alan

Urban

Title:

Chief

Financial Officer

4

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